Customer Publications (A total of 2600 papers published)
Calenduloside E suppresses calcium overload by promoting the interaction between L-type calcium channels and Bcl2-associated athanogene 3 to alleviate myocardial ischemia–reperfusion injury
Journal of Advanced Research (Elsevier) China, 31 October 2020
Cardiology
Key words: Calenduloside E, Myocardial Ischemia-Reperfusion Injury, L-Type Calcium Channelscalcium Overload, Bcl2-Associated Athanogene 3 [more]
Organism: Rat
Tissue: Heart
Pathological State: Myocardial Ischemia
B Cell Activating Factor (BAFF) Is Required for the Development of Intra-Renal Tertiary Lymphoid Organs in Experimental Kidney Transplantation in Rats
International Journal of Molecular Sciences (MDPI) Germany, 28 October 2020
Nephrology
Key words: Tertiary Lymphoid Organs, Kidney Transplantation, B Cells, BAFF [more]
Organism: Rat
Tissue: Kidney
Pathological State: Organ Transplantation
Proteomics of regenerated tissue in response to a titanium implant with a bioactive surface in a rat tibial defect model
Scientific Reports (Nature) Romania, 28 October 2020
Osteology
Key words: Bioinformatics, Biological Models, Fracture Repair, Immunological Techniques, Mass Spectrometry, Microscopy, Proteomic Analysis [more]
Organism: Human
Cell Line: Human mesenchymal stem cells (hMSCs)
Characterization of Negative Allosteric Modulators of the Calcium-Sensing Receptor for Repurposing as a Treatment of Asthma
The Journal of Pharmacology and Experimental Therapeutics (ASPET) UK, Austria, Australia, 28 October 2020
Pharmacology
Organism: Mouse
Tissue: Lung
Striosomes Mediate Value-Based Learning Vulnerable in Age and a Huntington's Disease Model
CELL (Cell Press) USA, 27 October 2020
Neuroscience
Key words: Corticostriatal, Approach-Avoidance, Cost-Benefit, Decision-Making, Utility, Subjective Value, Motivation, Parvalbumin Interneurons, VGluT1, Excitation-Inhibition Balance [more]
Organism: Mouse
Tissue: Brain
Pathological State: Huntington's Disease
The Immune Phenotype of Isolated Lymphoid Structures in Non-Tumorous Colon Mucosa Encrypts the Information on Pathobiology of Metastatic Colorectal Cancer
Cancers (MDPI) Austria, Switzerland, 25 October 2020
Oncology
Key words: Lymphoid Structures, Colonic Mucosa, Metastatic Colorectal Cancer, Immuno-Oncology, B Lymphocytes, Germinal Center, Tissue Image Cytometry, B-Cell Clonality, Compendium-Wide Analysis, Patient Stratification Strategy [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Cross‐section modified and highly elastic sutures reduce tissue incision and show comparable biocompatibility: in‐vitro and in‐vivo evaluation of novel thermoplastic urethane surgical threads
Journal of Biomedical Materials Research: Part B (Wiley) Germany, 24 October 2020
Tissue Engineering
Key words: Animal Trials, Biocompatibility, Elastic Sutures, Surface Modified Surgical Threads, Thermoplastic Polyurethane, Tissue Incision [more]
Organism: Rat
Tissue: Stomach
Direct signaling of TL1A-DR3 on fibroblasts induces intestinal fibrosis in vivo
Scientific Reports (Nature) USA, 23 October 2020
Immunology, Gastroenterology
Key words: Cytokines, Gastroenterology, Immunology, Inflammation, Inflammatory Bowel Disease [more]
Organism: Mouse
Cell Line: Mouse primary colonic fibroblasts
Increased Radiation-Associated T-Cell Infiltration in Recurrent IDH-Mutant Glioma
International Journal of Molecular Sciences (MDPI) Germany, 21 October 2020
Neuroscience
Key words: Lower-Grade Glioma, T-Cell Infiltration, TissueFAXS, Primary Tumors, Recurrent Tumors, Radiotherapy [more]
Organism: Human
Tissue: Brain
Pathological State: Cancer
Impaired autophagy increases susceptibility to endotoxin-induced chronic pancreatitis
Cell Death & Disease (Nature) Germany, 21 October 2020
Gastroenterology
Key words: Acute Pancreatitis, Chronic Pancreatitis [more]
Organism: Mouse
Tissue: Pancreas
Pathological State: Pancreatitis
Tissue remodeling macrophages morphologically dominate at the interface of polypropylene surgical meshes in the human abdomen
Hernia (Springer) Germany, UK, 18 October 2020
Tissue Engineering
Key words: Foreign Body Reaction, Macrophage, Collagen, Mesh, Fluorescence Microscopy [more]
Organism: Mouse
Tissue: Stomach
CDK5 Inhibition Abrogates TNBC Stem‐Cell Property and Enhances Anti‐PD‐1 Therapy
Advanced Science (Wiley) China, 15 October 2020
Oncology
Key words: Cancer Stem Cells, CD44 Variants, CDK5, Immune Checkpoint Blockade, PPARγ Phosphorylation, Triple‐Negative Breast Cancer, Tumor Microenvironment [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
Poly (ADP-ribose) polymerase inhibitor treatment as a novel therapy attenuating renal ischemia-reperfusion injury
Frontiers in Immunology (Frontiers Media S.A.) South Korea, Italy, France, 14 October 2020
Immunology
Key words: Acute Kidney Injury, Ischemia-Reperfusion Injury, Poly(ADP-Ribose) Polymerase (PARP) Inhibitor, Parthanatos, Inflammation, Translational Immunology [more]
Organism: Mouse
Tissue: Kidney
Pathological State: Acute Kidney Injury
Two Polyurethane Adhesives for PVDF Fixation Show Superior Biocompatibility in a Rat Model
Journal of Investigative Surgery (Taylor & Francis) Germany, The Netherlands, 14 October 2020
Tissue Engineering
Key words: Mesh Fixation, Polyurethane Adhesive, Incisional Hernia [more]
Organism: Rat
Tissue: Stomach
FATS regulates polyamine biosynthesis by promoting ODC degradation in an ERβ-dependent manner in non-small-cell lung cancer
Cell Death & Disease (Nature) China, 09 October 2020
Oncology
Key words: Apoptosis, Macroautophagy [more]
Organism: Human
Cell Line: Human NSCLC cell lines (A549, H520, H358, H460, H1299 and U87)
Immune contexture analysis in immuno‐oncology: applications and challenges of multiplex fluorescent immunohistochemistry
Clinical & Translational Immunology (Wiley) Australia, 07 October 2020
Immunology
Key words: FCS Express Image Cytometry, Immune Profiling, Multiplexed Fluorescent Immunohistochemistry, Quantitative Digital Pathology, Tumor Microenvironment, Vectra
Prenatal smoke exposure dysregulates lung epithelial cell differentiation in mouse offspring: role for AREG-induced EGFR signaling
APSselect (American Physiological Society) The Netherlands, Mongolia, Germany, China, 06 October 2020
Pulmonology
Key words: Amphiregulin, Epithelial Cell Differentiation, Lung Organoids, Prenatal Smoke Exposure [more]
Organism: Mouse
Tissue: Lung
Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during clinical latency
Nature Communications (Nature) Germany, Switzerland, 05 October 2020
Oncology
Key words: Breast Cancer, Cancer [more]
Organism: Mouse
Tissue: Breast
Pathological State: Cancer
Innovations present in the primate interneuron repertoire
Nature (Nature) USA, 30 September 2020
Neuroscience
Key words: Evolutionary Biology, Genetics of The Nervous System, Transcriptomics [more]
Organism: Marmoset
Tissue: Brain
Peptide-Based TNF-α-Binding Decoy Therapy Mitigates Lipopolysaccharide-Induced Liver Injury in Mice
Pharmaceuticals (MDPI) Taiwan, 29 September 2020
Hepathology
Key words: TNF-α, Necroptosis, Pyroptosis, Apoptosis, Autophagy, Mitochondrial Injury [more]
Organism: Mouse
Tissue: Liver
Prothymosin α activates type I collagen to develop a fibrotic placenta in gestational diabetes
Clinical Science (Portland Press) Taiwan, UK, 25 September 2020
Endocrinology
Key words: Fibrosis, Gestational Diabetes, Placenta, Prothymosin α, Trophoblast [more]
Pathological State: Gestational Diabetes
A Systemic Prime–Intrarectal Pull Strategy Raises Rectum-Resident CD8+ T Cells for Effective Protection in a Murine Model of LM-OVA Infection
Frontiers in Immunology (Frontiers Media S.A.) China, 24 September 2020
Immunology
Key words: Mucosal Immune Response, Rectum TRM, Prime–Pull Vaccination Strategy, HIV, Listeria Monocytogenes [more]
Organism: Mouse
Tissue: Lung
Discoidin Domain Receptors 1 Inhibition Alleviates Osteoarthritis via Enhancing Autophagy
International Journal of Molecular Sciences (MDPI) Taiwan, 23 September 2020
Rheumatology
Key words: Discoidin Domain Receptors 1 (Ddr1), Osteoarthritis (OA), Autophagy, Apoptosis, Terminal Differentiation [more]
Organism: Mouse
Tissue: Bone
Pathological State: Osteoarthritis
Mechanical stress regulates autophagic flux to affect apoptosis after spinal cord injury
Journal of Cellular and Molecular Medicine (Wiley) China, 17 September 2020
Neuroscience
Key words: Apoptosis, Autophagic Flux, Decompression, Mechanical Stress, mTOR, Spinal Cord Injury [more]
Organism: Rabbit
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Two common polymorphic variants of OATP4A1 as potential risk factors for colorectal cancer
Oncology Letters (Spandidos Publications) Austria, Hungary, 17 September 2020
Oncology
Organism: Human
Tissue: Colon
Pathological State: Cancer
Placental Alkaline Phosphatase Promotes Zika Virus Replication by Stabilizing Viral Proteins through BIP
mBio (American Society for Microbiolgy) China, 15 September 2020
Virology
Key words: BIP, Placental Alkaline Phosphatase, Zika Virus, Placental Trophoblast Cells [more]
Organism: Human
Cell Line: U-251 MG, JEG-3, and HK2 cells
IL-20 antagonist suppresses PD-L1 expression and prolongs survival in pancreatic cancer models
Nature Communications (Nature) Taiwan, 14 September 2020
Oncology
Key words: Interleukins, Pancreatic Cancer [more]
Organism: Human
Tissue: Pancreas
Pathological State: Cancer
In vitro function and in situ localization of Multidrug Resistance-associated Protein (MRP) 1 (ABCC1) suggest a protective role against methyl mercury-induced oxidative stress in the human placenta
Archives of Toxicology (Springer) Austria, Czech Republic, 11 September 2020
Toxicology
Key words: Multidrug Resistance-Associated Protein 1, Methyl Mercury, HTR-8/Svneo, MDCKII, Oxidative Stress, Human Placenta [more]
Organism: Human
Tissue: Placenta
The Metalloproteinase ADAMTS5 Is Expressed by Interstitial Inflammatory Cells in IgA Nephropathy and Is Proteolytically Active on the Kidney Matrix
The Journal of Immunology (American Association of Immnologists) UK, 11 September 2020
Immunology
Organism: Human
Tissue: Kidney
Iminostilbene, a novel small-molecule modulator of PKM2, suppresses macrophage inflammation in myocardial ischemia-reperfusion injury
Journal of Advanced Research (Elsevier) China, 09 September 2020
Cardiology
Key words: Myocardial Ischemia-Reperfusion, Macrophage, Iminostilbene, Pyruvate Kinase M2 [more]
Organism: Rat
Tissue: Heart
Pathological State: Myocardial Ischemia
Progranulin Administration Attenuates β-Amyloid Deposition in the Hippocampus of 5xFAD Mice Through Modulating BACE1 Expression and Microglial Phagocytosis
Frontiers in Cellular Neuroscience (Frontiers Media S.A.) China, 03 September 2020
Neuroscience
Key words: Alzheimer's Disease, Progranulin, Aβ, BACE1, Microglia [more]
Organism: Mouse
Tissue: Brain
Pathological State: Alzheimer's Disease
Integrin VLA-4 as a PET imaging biomarker of hyper-adhesion in transgenic sickle mice
Blood Advances (ASH Publications) USA, 03 September 2020
Cardiology
Key words: Adhesions, Biological Markers, Diagnostic Imaging, Integrins, Mice, Monoclonal Antibodies, Positron-Emission Tomography, Selectins, Flow Cytometry, Femur [more]
Organism: Mouse
Tissue: Bone, Spleen
Assessment of a long-term in vitro model to characterize the mechanical behavior and macrophage-mediated degradation of a novel, degradable, electrospun poly-urethane vascular graft
Journal of the Mechanical Behavior of Biomedical Materials (Elsevier) Austria, 03 September 2020
Tissue Engineering
Key words: Biodegradation, Mechanical Stability, Macrophages, Thermoplastic Polyurethane, Cell Culture, Rat Model [more]
Organism: Rat
Assessment of a long-term in vitro model to characterize the mechanical behavior and macrophage-mediated degradation of a novel, degradable, electrospun poly-urethane vascular graft
Journal of the Mechanical Behavior of Biomedical Materials (Elsevier) Austria, 03 September 2020
Biological Materials
Key words: Biodegradation, Mechanical Stability, Macrophages, Thermoplastic Polyurethane, Cell Culture, Rat Model
Murine induced pluripotent stem cell‐derived neuroimmune cell culture models emphasize opposite immune‐effector functions of interleukin 13‐primed microglia and macrophages in terms of neuroimmune toxicity
GLIA (Wiley) Belgium, Germany, Spain, The Netherlands, 31 August 2020
Neuroscience
Key words: Bioluminescence Imaging, Interleukin 13, iPSC, Macrophages, Microglia, Neurotoxicity, Transcriptome [more]
Organism: Human
Cell Line: iPSC‐macrophages
The Secretome of Stressed Peripheral Blood Mononuclear Cells Increases Tissue Survival in a Rodent Epigastric Flap Model
Bioengineering & Translational Medicine (Wiley) Austria, 30 August 2020
Tissue Engineering
Key words: Secretome, Angiogenesis, Flap Surgery, Necrosis Reconstructive Surgery, Tissue Regeneration [more]
Organism: Rat
Tissue: Skin
Alum triggers infiltration of human neutrophils ex vivo and causes lysosomal destabilization and mitochondrial membrane potential‐dependent NET‐formation
The FASEB Journal (Wiley) Austria, 29 August 2020
Cardiology
Key words: Aluminium Hydroxide, Vaccine, Adjuvant, Innate Response, Neutrophils, NET [more]
Organism: Human
Tissue: Skin
Radix Polygalae extract exerts antidepressant effects in behavioral despair mice and chronic restraint stress-induced rats probably by promoting autophagy and inhibiting neuroinflammation
Journal of Ethnopharmacology (Elsevier) China, 28 August 2020
Neuroscience
Key words: Depression, Radix Polygalae, Chronic Restraint Stress, Autophagy, Neuroinflammation [more]
Organism: Mouse
Tissue: Brain
Topography-Mediated Myotube and Endothelial Alignment, Differentiation, and Extracellular Matrix Organization for Skeletal Muscle Engineering
Polymers (MDPI) The Netherlands, 28 August 2020
Tissue Engineering
Key words: Myoblasts, Topography, Vascularization, Endothelial Cells, Skeletal Muscle, Extracellular Matrix [more]
Organism: Human
Tissue: Muscle
Effects of pharmacological calcimimetics on colorectal cancer cells over-expressing the human calcium-sensing receptor
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (Elsevier) Austria, 27 August 2020
Oncology
Key words: Calcium-Sensing Receptor, Calcimimetic, Colorectal Cancer, Inflammation, Intestine [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
The Effects of Skin Lesion Segmentation on the Performance of Dermatoscopic Image Classification
Computer Methods and Programs in Biomedicine (Elsevier) Austria, 26 August 2020
Medical Image Analysis
Key words: Skin Cancer, Dermatoscopy, Medical Image Analysis, Deep Learning, Effect of Segmentation on Classification
Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma
Genome Biology (BMC) South Korea, Italy, China, USA, 26 August 2020
Oncology
Organism: Human
Tissue: Brain
Pathological State: Cancer
Hindbrain Double-Negative Feedback Mediates Palatability-Guided Food and Water Consumption
CELL (Cell Press) USA, 24 August 2020
Neuroscience
Key words: Hunger, Thirst, Palatability, Locus Coeruleus, Locus Ceruleus, periLC, Ingestive Behavior, Appetite, In Vivo Calcium Imaging, GRIN Lens [more]
Organism: Mouse
Interruption of vascular endothelial growth factor receptor 2 signaling induces a proliferative pulmonary vasculopathy and pulmonary hypertension
Basic Research in Cardiology (Springer) Austria, Germany, 23 August 2020
Pulmonology
Key words: Pulmonary Hypertension, VEGFR-2, FLK, Kdr, Murine Model [more]
Organism: Mouse
Tissue: Lung
Loss of Bcl-6-expressing T follicular helper cells and germinal centers in COVID-19
CELL (Cell Press) USA, Canada, 19 August 2020
SARS-CoV-2
Key words: SARS-CoV-2, COVID-19, T Follicular Helper Cells, Germinal Centers, Double-Negative B Cells, Extra-Follicular B Cells, Plasmablasts, Humoral Immunity, TNF-α, Cytokine Dysregulation [more]
Organism: Human
Tissue: Lymphoid Tissue, Spleen
Pathological State: Covid-19
Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer
Nature Communications (Nature) USA, 19 August 2020
Oncology
Key words: Epigenomics, Prostate Cancer, Targeted Therapies [more]
Organism: Human
Tissue: Prostate
Pathological State: Cancer
Short-course radiotherapy promotes pro-inflammatory macrophages via extracellular vesicles in human rectal cancer
Journal for ImmunoTherapy of Cancer (BMJ Journals) Austria, 18 August 2020
Oncology
Key words: Macrophages, Radiotherapy, Tumor Microenvironment [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Epithelial cell–specific loss of function of Miz1 causes a spontaneous COPD-like phenotype and up-regulates Ace2 expression in mice
Science Advances (AAAS) USA, China, 14 August 2020
Immunology
Organism: Human
Tissue: Lung
Pathological State: Chronic Obstructive Pulmonary Disease
Prenatal smoke exposure dysregulates lung epithelial cell differentiation in mouse offspring-Role for AREG-induced EGFR signaling.
American Journal of Physiology (APS Journals) The Netherlands, China, 12 August 2020
Pulmonology
Key words: Prenatal Smoke Exposure, Epithelial Cell Differentiation, Amphiregulin, Lung Organoids [more]
Organism: Mouse
Tissue: Lung
Dysregulated Kras/YY1/ZNF322A/Shh transcriptional axis enhances neo-angiogenesis to promote lung cancer progression
Theranostics (Ivyspring International Publisher) Taiwan, 08 August 2020
Oncology
Key words: Lung Cancer, Kras, Shh, Transcription, Angiogenesis [more]
Organism: Human
Tissue: Lung
Pathological State: Cancer
The effects of CYP24A1 on clinicopathological features and the prognosis of pancreatic ductal adenocarcinoma
Translational Cancer Research (AME Publishing Company) China, 08 August 2020
Oncology
Key words: CYP24A1, Pancreatic Cancer, Prognosis [more]
Organism: Human
Tissue: Pancreas
Pathological State: Cancer
Human FBXL8 Is a Novel E3 Ligase Which Promotes BRCA Metastasis by Stimulating Pro-Tumorigenic Cytokines and Inhibiting Tumor Suppressors
Cancers (MDPI) Taiwan, Singapore, 07 August 2020
Oncology
Key words: FBXL8 SCF E3 Ubiquitin Ligase, CCND2, IRF5, Breast Cancer (BRCA) And Metastasis, Pro-Tumorigenic Microenvironment [more]
Organism: Human
Cell Line: MCF7 and MDA-MB231 cells
Pyramidal shaped ceria nano-biointerfaces for studying the early bone cell response
Applied Surface Science (Elsevier) Romania, 06 August 2020
Biological Materials
Key words: Pyramidal Shaped Ceria Nano-Biointerfaces, PLD, Cells Response [more]
Organism: Human
Cell Line: Human osteosarcoma cells (SaOs-2)
Sodium Cholate Bile Acid-Stabilized Ferumoxytol-Doxorubicin-Lipiodol Emulsion for Transcatheter Arterial Chemoembolization of Hepatocellular Carcinoma
Journal of Vascular and Interventional Radiology (Elsevier) USA, 06 August 2020
Oncology
Organism: Rat
Tissue: Liver
Pathological State: Cancer
Light‐emitting diode irradiation induces AKT/mTOR‐mediated apoptosis in human pancreatic cancer cells and xenograft mouse model
Journal of Cellular Physiology (Wiley Online Library) South Korea, 04 August 2020
Oncology
Key words: AKT/mTOR Pathway, Apoptosis, LED Irradiation, Pancreatic Cancer, Tumor Growth [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor
Nature Communications (Nature) USA, China, 04 August 2020
Virology
Key words: Chemical Tools, Proteomics, Virus–Host Interactions [more]
Organism: Human
Cell Line: HEK293T cells
Preclinical investigation of ovatodiolide as a potential inhibitor of colon cancer stem cells via downregulating sphere-derived exosomal β-catenin/STAT3/miR-1246 cargoes
American Journal of Cancer Research (e-Century Publishing Corporation) Taiwan, China, 01 August 2020
Oncology
Key words: Colon Cancer Stem Cells, Tumor Microenvironment, 5-FU Resistance, Tumorsphere Derived Exosomes, Β-Catenin/STAT3/MiR-1246 Signaling, Ovatodiolide [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Endocrine-disrupting chemicals rapidly affect intercellular signaling in Leydig cells
Toxicology and Applied Pharmacology (Elsevier) Czech Republic, Slovakia, 31 July 2020
Endocrinology
Key words: Connexins, Endocrine-Disrupting Chemicals, Gap Junctional Intercellular Communication, Leydig Cells, Reproductive Toxicants, Steroidogenesis [more]
Organism: Mouse
Cell Line: Leydig TM3 cells
A Curcumin Analog Exhibits Multiple Biologic Effects on the Pathogenesis of Alzheimer's Disease and Improves Behavior, Inflammation, and β-Amyloid Accumulation in a Mouse Model
International Journal of Molecular Sciences (MDPI) Taiwan, 30 July 2020
Neuroscience
Key words: Alzheimer's Disease Therapy, Curcumin Analog, TML-6, Aging, Bioavailability [more]
Organism: Mouse
Tissue: Brain
Pathological State: Alzheimer's Disease
Expression of Melatonin Receptor 1 in Rat Mesenteric Artery and Perivascular Adipose Tissue and Vasoactive Action of Melatonin
Cellular and Molecular Neurobiology (Springer) Slovakia, Austria, 30 July 2020
Cardiology
Key words: Rat Melatonin Receptor MT1, Melatonin, Mesenteric Artery (MA), Perivascular Fat Tissue (PVAT), Neurogenic Contraction [more]
Organism: Rat
Tissue: Eye, Brain
Hydroxysafflor Yellow A Protects Against Myocardial Ischemia/Reperfusion Injury via Suppressing NLRP3 Inflammasome and Activating Autophagy
Frontiers in Pharmacology (Frontiers Media S.A.) China, 30 July 2020
Cardiology
Key words: Myocardial Ischemia Reperfusion Injury, Hydroxysafflor Yellow A, NLRP3, Autophagy, AMPK [more]
Organism: Rat
Tissue: Heart
Pathological State: Myocardial Ischemia
NHF-derived carbon dots: prevalidation approach in breast cancer treatment
Scientific Reports (Nature) Romania, 29 July 2020
Oncology
Key words: Cancer, Drug Development, Medical Research, Oncology, Preclinical Research, Translational Research [more]
Organism: Human
Cell Line: HUVECs and PASMCs
BMI1-Mediated Pemetrexed Resistance in Non-Small Cell Lung Cancer Cells Is Associated with Increased SP1 Activation and Cancer Stemness
Cancers (MDPI) Taiwan, 27 July 2020
Oncology
Key words: BMI1, SP1, Pemetrexed Resistance, Non Small Cell Lung Cancer, Cancer Stem Cells, Epithelial–Mesenchymal Transition [more]
Organism: Mouse
Tissue: Lung
Pathological State: Cancer
A general method to optimize and functionalize red-shifted rhodamine dyes
Nature Methods (Nature) USA, 27 July 2020
Biological Methods
Key words: Chemical Biology, Chemical Tools, Fluorescence Imaging, Imaging [more]
Organism: Mouse
Tissue: Brain
Ready to go 3D? A semi-automated protocol for microwell spheroid arrays to increase scalability and throughput of 3D cell culture testing
Toxicology Mechanisms and Methods (Taylor & Francis) Czech Republic, USA, 26 July 2020
Biological Methods
Organism: Human
Cell Line: HL1-hT1 cells and HepG2 cells
Imaging of metabolic activity adaptations to UV stress, drugs and differentiation at cellular resolution in skin and skin equivalents–Implications for oxidative UV damage
Redox Biology (Elsevier) Austria, Italy, USA, 19 July 2020
Dermatology
Organism: Human
Tissue: Skin
Enterocyte-Based Bioassay via Quantitative Combination of Proinflammatory Sentinels Specific to 8-keto-trichothecenes
Frontiers in Immunology (Frontiers Media S.A.) South Korea, 16 July 2020
Immunology
Key words: 8-Keto-Trichothecene, Ribotoxic Stress, Inflammation, Epithelium, Reporter Biomonitoring [more]
Organism: Mouse
Tissue: Small Intestine
Neutrophil Extracellular Trap Degradation by Differently Polarized Macrophage Subsets
Arteriosclerosis, Thrombosis and Vascular Biology (American Heart Association) Austria, 16 July 2020
Cardiology
Key words: Aortic Aneurysm, Extracellular Traps, Humans, Macrophages, Thrombosis [more]
Organism: Mouse
Cell Line: Blood
Pre-and post-irradiation mild hyperthermia enabled by NIR-II for sensitizing radiotherapy
Biomaterials (Elsevier) China, 14 July 2020
Biological Materials
Key words: Au Nanobipyramids, Second Near-Infrared Window, Mild Hyperthermia, Radiotherapy [more]
Organism: Mouse
Tissue: Allograft Tumor
Pathological State: Cancer
Antidiabetic activity in vitro and in vivo of BDB, protein tyrosine phosphatase 1B selective inhibitor from Rhodonela conferviodes
British Journal of Pharmacology (Wiley) China, 14 July 2020
Pharmacology
Key words: Bromophenol, PTP1B Inhibitor, Selectivity, Cell Permeability, Oral Bioavailability [more]
Organism: Mouse
Tissue: Pancreas
Pathological State: Diabetes
Multivalent Clustering of Adhesion Ligands in Nanofiber-Nanoparticle Composites
Acta Biomaterialia (SSRN) France, USA, 13 July 2020
Biological Materials
Key words: Peptide Amphiphile, Silica Particles, Nanobiocomposites, Hybrid Biomaterials, Clustering [more]
Organism: Mouse
Cell Line: NIH 3T3 fibroblasts
Lycopene Inhibit IMQ-Induced Psoriasis-Like Inflammation by Inhibiting ICAM-1 Production in Mice
Polymers (MDPI) Taiwan, 09 July 2020
Dermatology
Key words: Lycopene, Psoriasis [more]
Organism: Mouse
Tissue: Skin
Pathological State: Psoriasis
Using Cytometry for Investigation of Purinergic Signaling in Tumor‐Associated Macrophages
Cytometry Part A (Wiley) Brazil, 07 July 2020
Oncology
Key words: Macrophage, TAM, Cancer Stem Cells, Purines, ATP, Purinergic System, EMT, Image Cytometry [more]
Organism: Human
Pathological State: Cancer
Cell Line: Macrophages
Multimodal single‐cell analysis reveals distinct radioresistant stem‐like and progenitor cell populations in murine glioma
GLIA (Wiley) USA, Italy, Sweden, 04 July 2020
Neuroscience
Key words: Glioma, Glioma Stem Cells, Myeloid Cells, Radiation Response, Radioresistance, Single‐Cell RNA Sequencing, SP Analysis [more]
Organism: Mouse
Tissue: Brain
Pathological State: Cancer
Catching Common Cold Virus with a Net: Pyridostatin Forms Filaments in Tris Buffer That Trap Viruses—A Novel Antiviral Strategy?
Viruses (MDPI) Austria, Sweden, 04 July 2020
Virology
Key words: Enterovirus, Rhinovirus, Pyridostatin, Filament, Extracellular Traps [more]
Organism: Human
Cell Line: HeLa Cells
Fewer tumour-specific PD-1+ CD8+ TILs in high-risk “Infiltrating” HPV− HNSCC
British Journal of Cancer (Nature) China, 03 July 2020
Oncology
Key words: Head and Neck Cancer, Tumour Immunology [more]
Organism: Human
Tissue: Head and Neck
Pathological State: Cancer
Slug Is A Surrogate Marker of Epithelial to Mesenchymal Transition (EMT) in Head and Neck Cancer
Journal of Clinical Medicine (MDPI) Austria, 30 June 2020
Oncology
Key words: Image Cytometry, p16, p53, Cancer Stem Cells, E-Cadherin, β -Catenin, EMT, Head and Neck Cancer [more]
Organism: Human
Tissue: Head and Neck
Pathological State: Cancer
Functional characterization of the basal amygdala-dorsal BNST pathway during contextual fear conditioning
eNeuro (Society for Neuroscience) USA, 29 June 2020
Neuroscience
Key words: Contextual Fear, Fear Memorybasal Amygdala, Bed Nucleus of The Stria Terminalis, Neural Circuits, Encoding, Fear Engram [more]
Organism: Mouse
Tissue: Brain
Tissues derived from reprogrammed Wharton's jelly stem cells of the umbilical cord as a platform to study gestational diabetes mellitus
Stem Cell Research (Elsevier) Singapore, 26 June 2020
Stem Cell Research
Key words: Gestational Diabetes Mellitus, Induced Pluripotent Stem Cells, Reprogramming, Wharton's Jelly Stem Cells, Pancreatic Cells [more]
Organism: Human
Pathological State: Gestational Diabetes
Cell Line: iPSCs
Comparison between paramagnetic and CD71 magnetic activated cell sorting of fetal nucleated red blood cells from the maternal blood
Journal of Clinical Laboratory Analysis (Wiley) Romania, 25 June 2020
Biological Methods
Key words: CD71, Fluorescent in Situ Hybridization, Magnetic‐Activated Cell Sorting, Nucleated Red Blood Cells, Prenatal Diagnosis [more]
Organism: Human
Cell Line: Blood
BMI1-KLF4 axis deficiency improves responses to neoadjuvant concurrent chemoradiotherapy in patients with rectal cancer
Radiotherapy and Oncology (Elsevier) Taiwan, 24 June 2020
Radiotherapy, Oncology
Key words: BMI1, CCRT, Rectal Cancers, Radioresistance [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
The chemokine lymphotactin and its recombinant variants in oral cancer cell regulation
Oral Diseases (Wiley) UK, 19 June 2020
Oncology
Key words: Cancer‐Associated Fibroblast, Lymphotactin, Oral Squamous Cell Carcinoma, Tumour Microenvironment, XCR1 [more]
Organism: Human
Tissue: Lymphoid Tissue
Pathological State: Cancer
p16 in highly malignant esophageal carcinomas: the correlation with clinicopathological factors and human papillomavirus infection
Virchows Archiv (Springer) Japan, Australia, Germany, 16 June 2020
Oncology
Key words: Esophagus, Small-Cell Carcinoma, Poorly Differentiated Squamous Cell Carcinoma, Basaloid Squamous Cell Carcinoma, P16, Human Papillomavirus [more]
Organism: Human
Tissue: Esophagus
Pathological State: Cancer
Reciprocal Regulation Between Indoleamine 2, 3-Dioxigenase 1 and Notch1 Involved in Radiation Response of Cervical Cancer Stem Cells
Cancers (MDPI) Taiwan, 12 June 2020
Oncology, Stem Cell Research
Key words: IDO1, Notch1, Radiation, Cervical Cancer, Cancer Stem Cells [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Tumor Microenvironment Targeting Nano–Bio Emulsion for Synergistic Combinational X‐Ray PDT with Oncolytic Bacteria Therapy
Advanced Healthcare Materials (Wiley) South Korea, USA, 11 June 2020
Oncology, Nanomedicine
Key words: Bacteriolytic Therapy, Nano–Bio Emulsions, Scintillating Nanoparticles, Tumor Microenvironments, X‐Ray Photodynamic Therapy (PDT) [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Regulatory T cells promote adipocyte beiging in subcutaneous adipose tissue
The FASEB Journal (Wiley) USA, China, 08 June 2020
Immunology
Key words: Epididymal White Adipose Tissue, Gonadal White Adipose Tissue, Macrophage Polarization, Regulatory T Cell, Subcutaneous Adipose Tissue, Uncoupling Protein‐1
Yttrium-90 Radioembolization and Tumor Hypoxia: Gas-challenge BOLD Imaging in the VX2 Rabbit Model of Hepatocellular Carcinoma
Academic Radiology (Elsevier) USA, 07 June 2020
Radiotherapy, Oncology
Key words: Oxygenation, Hepatic Radioembolization, Magnetic Resonance Imaging, Yttrium-90 [more]
Organism: Rabbit
Tissue: Kidney
Pathological State: Cancer
A prominent environmental endocrine disruptor, 4-nonylphenol, promotes endometriosis development via plasmacytoid dendritic cells
Molecular Human Reproduction (Oxford Academic) Taiwan, 04 June 2020
Reproductive Medicine
Key words: CD36, Endometriosis, Environmental Endocrine Disruptor, Estrous Cycle, IL-10, 4-Nonylphenol, Plasmacytoid Dendritic Cell [more]
Organism: Mouse
Tissue: Uterus
Pathological State: Endometriosis
A missense mutation of ErbB2 produces a novel mouse model of stillbirth associated with a cardiac abnormality but lacking abnormalities of placental structure
PLoS One (PLOS) UK, 03 June 2020
Reproductive Medicine
Key words: Mouse Models, Stillbirths, Embryos, Placenta, Fetal Death, Myocardium, Heart, Giant Cells [more]
Organism: Mouse
Tissue: Placenta
GPRC5A reduction contributes to pollutant benzo [a] pyrene injury via aggravating murine fibrosis, leading to poor prognosis of IIP patients
Science of The Total Environment (Elsevier) China, 03 June 2020
Toxicology
Key words: Pulmonary Fibrosis, GPRC5A, Benzo[A]Pyrene Pollution, Epithelium, Prognosis [more]
Organism: Human
Tissue: Lung
Pathological State: Pneumonia
AB0154 MERTK AND THE RESOLUTION OF INFLAMMATION IN IGG4-RELATED DISEASE
Annals of the Rheumatic Diseases (BMJ Journals) Italy, Japan, USA, 02 June 2020
Immunology
Organism: Human
Tissue: Tonsil
Oct4 promotes M2 macrophage polarization through upregulation of macrophage colony-stimulating factor in lung cancer
Journal of Hematology & Oncology (Springer) Taiwan, 01 June 2020
Oncology
Key words: Lung Cancer, Oct4, M2 Macrophage, Tumor-Associated Macrophage, M-CSF [more]
Organism: Human, Mouse
Tissue: Lung
Pathological State: Cancer
CD68+ macrophages as crucial components of the foreign body reaction demonstrate an unconventional pattern of functional markers quantified by analysis with double fluorescence staining
Journal of Biomedical Materials Research: Part B (Wiley) Germany, UK, 30 May 2020
Biological Materials
Key words: Fluorescence Microscopy, Foreign Body Reaction, Lymphocyte, Macrophage, Mesh [more]
Organism: Human
Tissue: Stomach
Pathological State: Abdominal Wall Hernia
CD4+ and CD8+ cytotoxic T lymphocytes may induce mesenchymal cell apoptosis in IgG4-related disease
Journal of Allergy and Clinical Immunology (Mosby) USA, Japan, The Netherlands, Canada, China, Italy, 29 May 2020
Immunology
Key words: IgG4-RD, CD4+CTL, CD8+CTL, Apoptosis, CD28lo, CD28(Null) [more]
Organism: Human
Tissue: Salivary Gland
Pathological State: Sjögren's Syndrome
Caveolar communication with xenobiotic-stalled ribosomes compromises gut barrier integrity
Communications Biology (Nature) South Korea, 27 May 2020
Gastroenterology
Key words: Biomarkers, Cell Biology, Chemokines, Inflammation, Signal Transduction [more]
Organism: Mouse
Tissue: Small Intestine
Interaction of different cell types with magnesium modified by plasma electrolytic oxidation
Colloids and Surfaces B: Biointerfaces (Elsevier) Colombia, The Netherlands, 26 May 2020
Biological Materials
Key words: Magnesium, PEO, Adipose-Derived Stromal, ASC, Differentiation, Cytotoxicity [more]
Organism: Human
Cell Line: HUVECs, ACSs
Absence of α-calcitonin gene-related peptide modulates bone remodeling properties of murine osteoblasts and osteoclasts in an age-dependent way
Mechanisms of Ageing and Development (Elsevier) Germany, 22 May 2020
Osteology
Key words: Bone, Osteoblast, Osteoclast, α -Calcitonin Gene-Related Peptide (α -CGRP), Osteopenia [more]
Organism: Mouse
Tissue: Bone
KRAB-Induced Heterochromatin Effectively Silences PLOD2 Gene Expression in Somatic Cells and is Resilient to TGFβ1 Activation
International Journal of Molecular Sciences (MDPI) The Netherlands, Hungary, 21 May 2020
Oncology
Key words: Pigenetic Editing, KRAB, Gene Repression, PLOD2, Fibrosis, Cancer [more]
Organism: Human
Cell Line: Human skin fibroblasts
Synergistic effect of cell-derived extracellular matrix and topography on osteogenesis of mesenchymal stem cells
ACS Applied Materials & Interfaces (ACS Publications) The Netherlands, 18 May 2020
Tissue Engineering
Key words: Extracellular Matrix, Topography, Mesenchymal Stem Cells, Osteogenic Differentiation, Mechanotransduction [more]
Organism: Human
Cell Line: hBM-MSCs
Biomimetic Multiscale Hierarchical Topography Enhances Osteogenic Differentiation of Human Mesenchymal Stem Cells
Advanced Materials Interfaces (Wiley) The Netherlands, China, 13 May 2020
Stem Cell Research
Key words: Collagen, Extracellular Matrix, Hierarchical Topography, Human Mesenchymal Stem Cells, Mechanotransduction, Osteogenic Differentiation [more]
Organism: Human
Cell Line: hBM‐MSCs
Deep immune profiling of ovarian tumors identifies minimal MHC-I expression after neoadjuvant chemotherapy as negatively associated with T-cell-dependent outcome
OncoImmunology (Taylor & Francis) The Netherlands, France, Canada, 13 May 2020
Oncology, Immunology
Key words: Epithelial Ovarian Cancer, Chemotherapy, Tumor Microenvironment, Cancer Immunology, MHC-I [more]
Organism: Human
Tissue: Ovaries, Lymphoid Tissue
Pathological State: Cancer
Progesteron receptor expression in insulin producing cells of neuroendocrine neoplasms
The Journal of Steroid Biochemistry and Molecular Biology (Elsevier) Japan, Germany, 11 May 2020
Endocrinology
Key words: Neuroendocrine Neoplasm, Insulinoma, Progesteron Receptor [more]
Organism: Human
Tissue: Pancreas
Pathological State: Cancer
Immune landscape in Burkitt lymphoma reveals M2-macrophage polarization and correlation between PD-L1 expression and non-canonical EBV latency program
Infectious Agents and Cancer (BMC) Italy, Germany, UK, Kenya, Egypt,, 06 May 2020
Oncology, Virology
Key words: Burkitt Lymphoma, Tumour Microenvironment, EBV, PD-L1, Immunotherapy, Immune Checkpoint [more]
Organism: Human
Tissue: Lymphoid Tissue
Pathological State: Cancer
Decoupling the Amplitude and Wavelength of Anisotropic Topography and the Influence on Osteogenic Differentiation of Mesenchymal Stem Cells Using a High-Throughput Screening Approach
ACS Applied Bio Materials (ACS Publications) The Netherlands, China, 06 May 2020
Stem Cell Research
Organism: Human
Cell Line: hBM-MSCs
High‐Throughput Screening and Hierarchical Topography‐Mediated Neural Differentiation of Mesenchymal Stem Cells
Advanced Healthcare Materials (Wiley Online Library) The Netherlands, 04 May 2020
Stem Cell Research
Key words: Anisotropic Topography, Hierarchical Structures, High‐Throughput Screening, Human Mesenchymal Stem Cells, Neural Differentiation [more]
Organism: Human
Cell Line: hMSCs
The Prognostic and Predictive Value of SOX2+ Cell Densities in Patients Treated for Colorectal Cancer
Cancers (MDPI) Australia, 29 April 2020
Oncology
Key words: SOX2, Colorectal Cancer, Chemotherapy, Prognosis, Oxaliplatin, 5-Fluorouracil, Cancer Stem Cell [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
ATP and spontaneous calcium oscillations control neural stem cell fate determination in Huntington's disease: a novel approach for cell clock research
Molecular Psychiatry (Nature) Japan, Brazil, USA, Poland, 29 April 2020
Cell Biology, Neuroscience
Key words: Cell Biology, Diseases, Molecular Biology, Neuroscience [more]
Organism: Mouse
Cell Line: E14Tg2A cells
Acute Effects of Pulmonary Exposure to Zinc Oxide Nanoparticles on Brain in Vivo 2
Aerosol and Air Quality Research (AAQR) Taiwan, 25 April 2020
Nanomedicine
Key words: Autophagy, Central Nervous System, Elevated Plus Maze, Morris Water Maze, Nanoparticle, Ubiquitin. [more]
Organism: Rat
Tissue: Brain
A characteristic expression pattern of core circadian genes in the diurnal tree shrew
Neuroscience (Elsevier) China, 25 April 2020
Neuroscience
Key words: Tree Shrew, Diurnal Animal, Circadian Gene, Brain Rhythm, Peripheral Rhythm [more]
Organism: Tree Shrew
Tissue: Brain
In vitro and in vivo biocompatibility study of surface modified TiN deposited on Ti6Al4V using high-power impulse magnetron sputtering technique
Surface and Coatings Technology (Elsevier) Taiwan, 21 April 2020
Biological Materials
Key words: HiPIMS, TiN, Acrylamide Crosslinking, BMP2 Attachment, In Vitro And In Vivo Studies [more]
Organism: Mouse
Tissue: Skin
Characterization of CD103+ CD8+ tissue‑resident T cells in esophageal squamous cell carcinoma: may be tumor reactive and resurrected by anti‑PD‑1 blockade
Cancer Immunology, Immunotherpay (Springer) China, 20 April 2020
Oncology, Immunology
Key words: CD103, Tissue-Resident T Cells, Tumor-Infiltrating Lymphocytes, Esophageal Squamous Cell Carcinoma [more]
Organism: Mouse
Tissue: Skin
Pathological State: Cancer
The Effect of the Chorion on Size-Dependent Acute Toxicity and Underlying Mechanisms of Amine-Modified Silver Nanoparticles in Zebrafish Embryos
International Journal of Molecular Sciences (MDPI) Taiwan, 20 April 2020
Nanomedicine
Key words: Zebrafish Embryos, Acute Toxicity, Silver Nanoparticles, Chorion Pore Size, Lysosomal Activity, Apoptosis [more]
Organism: Zebrafish
Tissue: Whole Organism
Macrophages and Fibroblasts Differentially Contribute to Tattoo Stability
Dermatology (Karger) France, Germany, 19 April 2020
Dermatology
Key words: Tattoo, Macrophage, Fibroblast, Tattoo Maintenance [more]
Organism: Human
Tissue: Skin
Dynamic Malignant Wave of Ribosome-insulted Gut Niche via the Wnt-CTGF/CCN2 Circuit
iScience (Cell Press) South Korea, 18 April 2020
Cell Biology
Key words: CTGF/CCN2, Wnt, Ribosomal Insult, Colorectal Cancer, Tumor Niche [more]
Organism: Human
Cell Line: HCT8 and HCT116 cells
Antibody targeting of B7-H4 enhances the immune response in urothelial carcinoma
OncoImmunology (Taylor & Francis) USA, 16 April 2020
Oncology, Immunology
Key words: Immunotherapy, Bladder Cancer, Macrophage, T Cell, Checkpoint Inhibitor [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Functional diversity between HSP70 paralogs due to variable interactions with specific co-chaperones.
Journal of Biological Chemistry (ASBMB) The Netherlands, Germany, 13 April 2020
Cell Biology
Key words: Hsp110, HSPA4, HSPH2, Protein Folding, Superoxide Dismutase (SOD), 70 Kilodalton Heat Shock Protein (Hsp70), Proteostasis Amyotrophic Lateral Sclerosis (ALS) (Lou Gehrig Disease), Heat Shock Protein (HSP) [more]
Organism: Human
Cell Line: HEK293 Cells
IFN-κ suppresses the replication of influenza A viruses through the IFNAR-MAPK-Fos-CHD6 axis
Science Signaling (AAAS) China, 07 April 2020
Immunology
Organism: Mouse
Tissue: Lung
EMI2 expression as a poor prognostic factor in patients with breast cancer
Kaohsiung Journal of Medical Sciences (Wiley) Taiwan, Japan, 06 April 2020
Oncology
Key words: Breast Cancer, EMI2 (FBXO43), Metastasis
Topography induced stiffness alteration of stem cells influences osteogenic differentiation
Biomaterials Science (Royal Society of Chemistry) The Netherlands, China, 05 April 2020
Stem Cell Research
Organism: Human
Cell Line: hBM-MSCs
Loss of S6K1 But Not S6K2 in the Tumor Microenvironment Suppresses Tumor Growth by Attenuating Tumor Angiogenesis
Translational Oncology (Elsevier) South Korea, 03 April 2020
Oncology
Organism: Human
Cell Line: Endothelial Cells
Anti-apoptotic molecule BCL2 is a therapeutic target in steroid-refractory graft-versus-host disease
Journal of Investigative Dermatology (Elsevier) Austria, 02 April 2020
Dermatology
Organism: Human
Tissue: Skin
Thyrotropin receptor signaling deficiency impairs spatial learning and memory in mice
Journal of Endocrinology (Society for Endocrinology) China, 01 April 2020
Endocrinology
Distinct galectin profile in inflammation-mediated cartilage damage
Osteoarthritis and Cartilage (OARSI Journal) Austria, 01 April 2020
Osteology
Organism: Mouse
Tissue: Joint Tissue, Bone
Pathological State: Arthritis
Anti-VEGF Treatment Enhances CD8+ T-Cell Antitumor Activity by Amplifying Hypoxia
Cancer Immunology Research (AACR Publications) USA, 27 March 2020
Oncology
Key words: VEGF, CD8+ T Cells, Hypoxia, Angiogenesis, Hypoxia-Inducible Factor-1a [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Elevation of CD109 promotes metastasis and drug resistance in lung cancer via activation of EGFR‐AKT‐mTOR signaling
Cancer Science (Japanese Cancer Association) Taiwan, 25 March 2020
Oncology
Key words: CD109, EGFR, Lung Cancer, Metastasis, mTOR [more]
Organism: Mouse
Tissue: Lung
Pathological State: Cancer
Functionalized graphene oxide thin films for anti-tumor drug delivery to melanoma cells
Frontiers in Chemistry (Frontiers Media S.A.) Romania, 25 March 2020
Nanomedicine
Organism: Human
Cell Line: HDF cells, NHEM cells
Advancements in developing an effective and preventive dengue vaccine
Future Virology (Future Medicine) Pakistan, 24 March 2020
Virology
Key words: Aedes Mosquito, Chimeric Vaccine, Dengue Fever, Dengue Virus, Endemic, Pandemic, Public Health, Subtropical, Tropical, Vaccines
Soluble Alpha-Klotho Alleviates Cardiac Fibrosis without Altering Cardiomyocytes Renewal
International Journal of Molecular Sciences (MDPI) Taiwan, 22 March 2020
Cardiology
Key words: Klotho, FGF-23, Cardiac Fibrosis, Genetic Fate Mapping [more]
Organism: Mouse
Tissue: Heart
Iron and advanced glycation end products: Emerging role of iron in androgen deficiency in obesity
Antioxidants (MDPI) Taiwan, 22 March 2020
Endocrinology
Key words: Obesity, Iron, Fat, Advanced Glycation End Products, Testis, Testosterone [more]
Organism: Rat
Tissue: Liver, Testis
Pathological State: Obesity
Upregulation of protein synthesis and proteasome degradation confers sensitivity to proteasome inhibitor bortezomib in myc-atypical teratoid/rhabdoid tumors
Cancers (MDPI) Taiwan, Vietnam, 22 March 2020
Oncology
Key words: Myc- ATRTs, Protein Synthesis, Proteasome Degradation, Bortezomib, p53 [more]
Organism: Human, Mouse
Tissue: Brain, Xenograft Tumor
Role of HMGB1 in an Animal Model of Vascular Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion
International Journal of Molecular Sciences (MDPI) Taiwan, 21 March 2020
Neuroscience
Key words: Vascular Cognitive Impairment, Chronic Cerebral Hypoperfusion, Modified Bilateral Common Carotid Artery Occlusion, HMGB1 [more]
Organism: Mouse
Tissue: Brain
Analysis of sensitivity and specificity: precise recognition of neutrophils during regeneration of contused skeletal muscle in rats
Forensic Sciences Research (Taylor & Francis) China, 19 March 2020
Neuroscience
Key words: Forensic Sciences, Forensic Pathology, Immunohistochemistry, TissueFaxs 200 Digital Pathological Analysis System, Parameter Optimization, Cut-Off Value Of Staining Area, Neutrophil Staining Area [more]
Organism: Rat
Tissue: Muscle
Autophagy attenuates high glucose-induced oxidative injury to lens epithelial cells
Bioscience Reports (Portland Press) China, 18 March 2020
Endocrinology
Key words: Diabetic Cataract, High Glucose, Autophagy, Oxidative Stress, Lens [more]
Organism: Mouse
Tissue: Eye
MeCP2 mediates transgenerational transmission of chronic pain
Progress in Neurobiology (Elsevier) China, USA, 18 March 2020
Neuroscience
Key words: Chronic Pain, MeCP2, Primary Somatosensory Cortex, Glutamatergic Neuron, Transgenerational Transmission [more]
Organism: Mouse
Tissue: Brain
Jdp2-deficient granule cell progenitors in the cerebellum are resistant to ROS-mediated apoptosis through xCT/Slc7a11 activation
Scientific Reports (Nature) Taiwan, Japan, 18 March 2020
Neuroscience
Key words: Apoptosis, Molecular Neuroscience [more]
Organism: Mouse
Tissue: Brain
Regulatory T cells specifically suppress conventional CD8αβ T cells in intestinal tumors of APC Min/+ mice
Cancer Immunology, Immunotherpay (Springer) Sweden, 17 March 2020
Immunology
Key words: Regulatory T Cells, APCmin/+, Colon Cancer, Tumor-Infiltrating Lymphocytes, Anti-Tumor Immunity [more]
Organism: Mouse
Tissue: Small Intestine
Pathological State: Cancer
Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis
Nature Metabolism (Nature) China, 16 March 2020
Oncology
Key words: Cancer, Cancer Metabolism, Cell Growth [more]
Organism: Human
Tissue: Lymphoid Tissue
Pathological State: Cancer
Long-Term Deleterious Effects of Short-term Hyperoxia on Cancer Progression—Is Brain-Derived Neurotrophic Factor an Important Mediator? An Experimental Study
Cancers (MDPI) Romania, 14 March 2020
Oncology
Key words: Cancer Progression, Breast Cancer, Hyperoxia, Perioperative, Metastasis, BDNF, Vimentin, E-Cadherin, Epithelial Mesenchymal Transition, Angiogenesis [more]
Cell Line: human MDA-MB-231 and murine 4T1 TNBC cell lines
Proteomic profiling of hepatic stellate cells in alcohol liver fibrosis reveals proteins involved in collagen production
Alcohol (Elsevier) China, 12 March 2020
Hepathology
Key words: Ethanol, Liver, HSC, Proteomics, Collagen, Ndufv2 [more]
Organism: Rat
Tissue: Liver
Pathological State: Liver Fibrosis
Commercial 4-dimensional echocardiography for murine heart volumetric evaluation after myocardial infarction
Cardiovascular Ultrasound (BMC) USA, 12 March 2020
Cardiology
Organism: Mouse
Tissue: Heart
Pathological State: Myocardial Infarction
Placental Morphology and Cellular Characteristics in Stillbirths in Women With Diabetes and Unexplained Stillbirths
Archives of Pathology & Laboratory Medicine (College of American Pathologists) UK, 09 March 2020
Reproductive Medicine
Organism: Human
Tissue: Placenta
Pathological State: Diabetes
PTH hypersecretion triggered by a GABA B1 and Ca 2+-sensing receptor heterocomplex in hyperparathyroidism
Nature Metabolism (Nature) USA, 09 March 2020
Endocrinology
Key words: Calcium and Vitamin D, Homeostasis, Mechanisms Of Disease, Parathyroid Diseases [more]
Organism: Mouse
Tissue: Thyroid
Low-frequency dual-frequency ultrasound-mediated microbubble cavitation for transdermal minoxidil delivery and hair growth enhancement
Scientific Reports (Nature) Taiwan, 09 March 2020
Tissue Engineering
Key words: Biophysics, Medical Research [more]
Organism: Mouse
Tissue: Skin
Surface functionalization of pegylated gold nanoparticles with antioxidants suppresses nanoparticle-induced oxidative stress and neurotoxicity
Chemical Research in Toxicology (ACS Publications) China, 05 March 2020
Toxicology
Key words: Pegylation, Gold Nanoparticle, Neurotoxicity, Drug Delivery [more]
Organism: Mouse
Tissue: Brain
Topography Mediated Fibroblast Cell Migration is Influenced by Direction, Wavelength, and Amplitude
ACS Applied Bio Materials (ACS Publications) , 04 March 2020
Biological Materials
Key words: Topography, Gradient, Cell Migration, Biointerface, Wound Healing [more]
Organism: Human
Cell Line: Fibroblasts
Elevation of CD109 promotes metastasis and drug resistance in lung cancer via activation of EGFR-AKT-mTOR signaling
Cancer Science (Wiley) Taiwan, 04 March 2020
Oncology
Key words: CD109, EGFR, Lung Cancer, Metastasis, mTOR [more]
Organism: Mouse
Tissue: Lung
Pathological State: Cancer
A potent peptide-steroid conjugate accumulates in cartilage and reverses arthritis without evidence of systemic corticosteroid exposure
Science Translational Medicine (AAAS) USA, 04 March 2020
Endocrinology
Organism: Human
Tissue: Joint Tissue
Targeting alveolar macrophages shows better treatment response than deletion of interstitial macrophages in EGFR mutant lung adenocarcinoma
Immunity, Inflammation and Disease (Wiley) Germany, 03 March 2020
Immunology, Oncology
Key words: Alveolar Macrophages, Clodronate Liposomes, EGFR Mutation, Interstitial Macrophages, Lung Cancer [more]
Organism: Mouse
Tissue: Lung
Pathological State: Cancer
Artificial intelligence as the next step towards precision pathology
Journal of Internal Medicine (Wiley) Sweden, 03 March 2020
Medical Imaging
Key words: Artificial Intelligence, Deep Learning, Digital Image Analysis, Digital Pathology, Machine Learning, Pathology
Discoidin domain receptor 1 regulates endochondral ossification through terminal differentiation of chondrocytes
The FASEB Journal (FASEB) Taiwan, 03 March 2020
Osteology
Key words: Chondrocytes, DDR1, Discoidin Domain Receptor 1, Endochondral Ossification, Skeletal Development [more]
Organism: Mouse
Tissue: Bone
Cytotoxic T Cells and their Activation Status are Independent Prognostic Markers in Meningiomas
Clinical Cancer Research (AACR Publications) Germany, 02 March 2020
Oncology
Key words: Clinically Aggressive Meningioma, T-Cell Infiltration, Primary and Recurrent Tumors TILs, PD-1 [more]
Organism: Human
Tissue: Brain
Pathological State: Cancer
Transcranial direct current stimulation alleviates seizure severity in kainic acid-induced status epilepticus rats
Experimental Neurology (Elsevier) Taiwan, USA, 29 February 2020
Neuroscience
Key words: Status Epilepticus, Seizure, Electroencephalography, Mossy Fiber Sproutin, gBrain -Derived Neurotrophic Factor, Transcranial Direct Current Stimulation [more]
Organism: Rat
Tissue: Brain
Pathological State: Seizures
The Determination of Immunomodulation and Its Impact on Survival of Rectal Cancer Patients Depends on the Area Comprising a Tissue Microarray
Cancers (MDPI) Austria, 29 February 2020
Oncology
Key words: Irradiated Rectal Cancer, Immunoscore, Virtual Microscopy, Digital Pathology, Tissue Microarray (TMA) [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Dermal fillers do not induce upregulation of NLRP3 inflammasomes or expression of inflammatory cytokines in granulomas
Journal of Cosmetic Dermatology (Wiley) Germany, Japan, 28 February 2020
Dermatology
Key words: Caspase, Fillers, Granulomas, Inflammasome, Interleukins [more]
Organism: Human
Tissue: Skin
A transcriptionally distinct CXCL13+ CD103+ CD8+ T-cell population is associated with B-cell recruitment and neoantigen load in human cancer
Cancer Immunology Research (AACR Publications) The Netherlands, UK, Canada, 27 February 2020
Oncology
Key words: CXCL13, TGFβ1, Tertiary Lymphoid Structures, CD103+ T Cell, Immune Checkpoint Inhibitors [more]
Organism: Human
Pathological State: Cancer
Ultrasound-responsive neurotrophic factor-loaded microbubble-liposome complex: Preclinical investigation for Parkinson's disease treatment
Journal of Controlled Release (Elsevier) Taiwan, 27 February 2020
Neuroscience
Key words: Ultrasound (US)-Targeted Microbubble Destruction (UTMD), Gene Therapy, Blood-Brain Barrier Opening, GDNF, BDNF [more]
Organism: Mouse
Tissue: Brain
Pathological State: Parkinson's Disease
cPLA2α reversibly regulates different subsets of cancer stem cells transformation in cervical cancer
Stem Cells (Wiley) China, 26 February 2020
Oncology
Key words: Cancer Stem Cells, CD133, CD24, CD44, cPLA2α, Epithelial‐Mesenchymal Transition [more]
Organism: Human
Tissue: Uterus
Pathological State: Cancer
Indoprofen prevents muscle wasting in aged mice through activation of PDK1/AKT pathway
Journal of Cachexia, Sarcopenia and Muscle (Wiley) South Korea, 25 February 2020
Neuroscience
Key words: Exercise Mimetic, Hypertrophic Response, Indoprofen, Muscle Wasting, Muscle Weakness, PDK1 [more]
Organism: Mouse
Tissue: Muscle
Prefrontal Cortex Corticotropin-Releasing Factor Neurons Control Behavioral Style Selection under Challenging Situations
Neuron (Cell Press) China, 25 February 2020
Neuroscience
Key words: Corticotropin-Releasing Factor Neurons, Prefrontal Cortex, Behavioral Style Selection, Social Defeat Stress [more]
Organism: Mouse
Tissue: Brain
Sox2 induces tumorigenesis and angiogenesis of early-stage esophageal squamous cell carcinoma through secretion of Suprabasin
Carcinogenesis (Oxford University Press) Japan, 14 February 2020
Oncology
Key words: Sox2, Esophageal Cancer, Suprabasin, Carcinogenesis, Angiogenesis [more]
Organism: Human
Tissue: Esophagus
Pathological State: Cancer
The Accumulation and Effects of Liposomal Doxorubicin in Tissues Treated by Radiofrequency Ablation and Irreversible Electroporation in Liver: In Vivo Experimental Study on Porcine Models
CardioVascular and Interventional Radiology (Springer) Czech Republic, Israel, 13 February 2020
Cardiology
Key words: Liposomal Doxorubicin, Radiofrequency Ablation, Irreversible Electroporation [more]
Organism: Pig
Tissue: Liver
The Impact of Cand1 in Prostate Cancer
Cancers (MDPI) Austria, Germany, 12 February 2020
Oncology
Key words: Prostate Cancer, Cand1, Cancer Aggressiveness, Survival, Tumor Recurrence, Mutation, Enzalutamide Resistance [more]
Organism: Human
Tissue: Prostate
Pathological State: Cancer
Epithelial to Mesenchymal Transition: A Mechanism that Fuels Cancer Radio/Chemoresistance
Cells (MDPI) Austria, Hungary, 12 February 2020
Oncology
Key words: Silibinin, MRX34, PD-L1, NRF2, Krüppel-Like Factors (KLFs), Neurotrophin [more]
Organism: Human
Tissue: Mucosa
Pathological State: Cancer
MRI radiomics for early prediction of response to vaccine therapy in a transgenic mouse model of pancreatic ductal adenocarcinoma
Journal of Translational Medicine (BMC) USA, China, 10 February 2020
Gastroenterology
Key words: Dendritic Cell Vaccine, Machine Learning, Magnetic Resonance Imaging, Pancreatic Ductal Adenocarcinoma, Radiomics [more]
Organism: Mouse
Tissue: Xenograft Tumor, Pancreas
Pathological State: Cancer
Single cell approaches to address adipose tissue stromal cell heterogeneity
Biochemical Journal (Portland Press) USA, 06 February 2020
Endocrinology
Key words: Plasticity, Single Cell RNA-Seq, Stromal Cells, White Adipose Tissue
Acquisition of chromosome instability is a mechanism to evade oncogene addiction
EMBO Molecular Medicine (EMBO press) Germany, 06 February 2020
Oncology
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Chondroitin sulfate synthase 1 enhances proliferation of glioblastoma by modulating PDGFRA stability
Oncogenesis (Nature) Taiwan, 04 February 2020
Oncology
Key words: CNS Cancer, Growth Factor Signalling [more]
Organism: Human
Tissue: Brain
Pathological State: Cancer
Araloside C attenuates atherosclerosis by modulating macrophage polarization via Sirt1-mediated autophagy
Aging (Impact Journals) China, 31 January 2020
Cardiology
Key words: Atherosclerosis, Macrophage Polarization, Autophagy, Sirt1, Araloside C [more]
Organism: Mouse
Tissue: Heart
Pathological State: Atherosclerosis
The RNA-Binding Ubiquitin Ligase MEX3A Affects Glioblastoma Tumorigenesis by Inducing Ubiquitylation and Degradation of RIG-I
Cancers (MDPI) Italy, 30 January 2020
Oncology
Key words: Glioblastoma Multiforme (GB), Ubiquitylation, E3-Ligase, MEX3A, RIG-I [more]
Organism: Human
Pathological State: Cancer
Cell Line: glioblastoma A-172 cells
Unidirectional rotating molecular motors dynamically interact with adsorbed proteins to direct the fate of mesenchymal stem cells
Science Advances (AAAS) China, The Netherlands, 29 January 2020
Biological Materials
Organism: Human
Cell Line: hBM-MSCs Cells
Circular RNA MAPK4 (circ-MAPK4) inhibits cell apoptosis via MAPK signaling pathway by sponging miR-125a-3p in gliomas
Molecular Cancer (BMC) China, USA, 28 January 2020
Oncology
Key words: Circ-MAPK4, P38/MAPK Signaling Pathway, MiR-125a-3p, Gliomas, Apoptosis [more]
Organism: Mouse
Tissue: Xenograft Tumor, Brain
Pathological State: Cancer
Cytotoxic CD4+ T lymphocytes may induce epithelial cell apoptosis in systemic sclerosis
The Journal of Clinical Investigation (American Society of Clinical Investigation) USA, Japan, The Netherlands, Canada, China, 28 January 2020
Immunology
Organism: Human
Tissue: Skin
The Establishment of Esophageal Precancerous Lesion Model by Using p53 Conditional Knockout Mouse in Esophageal Epithelium
BioMed Research International (Hindawi Publishing Corporation) China, 25 January 2020
Oncology
Organism: Mouse
Tissue: Esophagus
Effects of exosome-mediated delivery of myostatin propeptide on functional recovery of mdx mice
Biomaterials (Elsevier) China, 25 January 2020
Biological Materials
Key words: Exosome, Duchenne Muscular Dystrophy, Myostatin, Propeptide [more]
Organism: Rat
Tissue: Muscle, Liver, Kidney
Surfactant expression defines an inflamed subtype of lung adenocarcinoma brain metastases that correlates with prolonged survival
Clinical Cancer Research (AACR Publications) Germany, 17 January 2020
Oncology
Organism: Human
Tissue: Lung
Pathological State: Cancer
Cordyceps militaris induces apoptosis in ovarian cancer cells through TNF-α/TNFR1-mediated inhibition of NF-κB phosphorylation
BMC Complementary Medicine and Therapies (BMC) South Korea, 13 January 2020
Oncology
Key words: Apoptosis, TNF-α, TNFR1, NF-κB, C. Militaris [more]
Organism: Human
Cell Line: SKOV-3 Cells
High Extra-tumoral Mast Cell Counts are Associated with a Higher Risk of Adverse Prostate Cancer Outcomes
Cancer Epidemiology, Biomarkers & Prevention (AACR Publications) USA, 13 January 2020
Oncology
Novel titanium-apatite hybrid scaffolds with spongy bone-like micro architecture intended for spinal application: In vitro and in vivo study
Materials Science and Engineering: C (Elsevier) Romania, Spain, 11 January 2020
Biological Materials
Key words: Titanium-Apatite Hybrid Scaffolds, Osteogenic Biomimetic Porous Scaffolds, Hydroxyapatite Bioactive Matrix, Bone Restoration, Spinal Fusion, Additive Manufacturing [more]
Organism: Human
Cell Line: Osteoblasts
Fecal Microbiota Transplantation Prevents Intestinal Injury, Upregulation of Toll-Like Receptors, and 5-Fluorouracil/Oxaliplatin-Induced Toxicity in Colorectal Cancer
International Journal of Molecular Sciences (MDPI) Taiwan, 08 January 2020
Oncology, Microbiology
Key words: FOLFOX, Fecal Microbiota Transplant, Intestinal Mucositis, Apoptosis, Gut Microbiota [more]
Organism: Mouse
Tissue: Small Intestine
Pathological State: Cancer
Impact of the Sensory and Sympathetic Nervous System on Fracture Healing in Ovariectomized Mice
International Journal of Molecular Sciences (MDPI) Germany, 08 January 2020
Neuroscience
Key words: Fracture, Substance P, Alpha-CGRP, Sympathectomy, Sympathetic Nerve Fibers, Ovariectomy, Sensory Nervous System, Bone Repair, Bone Remodeling [more]
Organism: Mouse
Tissue: Bone
Sensory neuropeptides are required for bone and cartilage homeostasis in a murine destabilization-induced osteoarthritis model
Bone (Elsevier) Germany, 08 January 2020
Osteology
Key words: Osteoarthritis, Destabilization of The Medial Meniscus, Substance P, Alpha- Calcitonin Gene-Related Peptide, Bone, Cartilage [more]
Organism: Mouse
Tissue: Bone
Racial difference in prostate cancer cell telomere lengths in men with higher-grade prostate cancer: a clue to the racial disparity in prostate cancer outcomes
Cancer Epidemiology, Biomarkers & Prevention (AACR Publications) USA, 08 January 2020
Oncology
Efficient Labeling Of Mesenchymal Stem Cells For High Sensitivity Long-Term MRI Monitoring In Live Mice Brains
International Journal of Nanomedicine (Dove Press) Taiwan, 08 January 2020
Nanomedicine
Key words: Iron Oxide Nanoparticles, FGF21, Regenerative Medicine, Tracking of Cells, Non-Invasive Imaging Modality [more]
Organism: Human
Cell Line: Mesenchymal Stem Cells
Protective Effects of Chlorogenic Acid on Cerebral Ischemia/Reperfusion Injury Rats by Regulating Oxidative Stress-Related Nrf2 Pathway
Drug Design, Development and Therapy (Dove Press) China, 07 January 2020
Neuroscience
Key words: Cerebral Ischemia/Reperfusion Injury, Chlorogenic Acid, Oxidative Stress, Neuroprotection, NF-E2-Related Factor 2 Pathway [more]
Organism: Rat
Tissue: Brain
Pathological State: Cerebral Ischemia
The MyoD family inhibitor domain-containing protein enhances the chemoresistance of cancer stem cells in the epithelial state by increasing β-catenin activity
Oncogene (Nature) Taiwan, 07 January 2020
Oncology
Key words: Non-Small Lung Cancer, Prognostic [more]
Organism: Human
Tissue: Lung
Pathological State: Cancer
TIAM2S as a novel regulator for serotonin level enhances brain plasticity and locomotion behavior
The FASEB Journal (Wiley) Taiwan, 07 January 2020
Neuroscience
Key words: Guanine Nucleotide Exchange Factor (GEF), Hyperlocomotion, Neuroplasticity, Serotonergic Fiber, Serotonin (5‐HT), TIAM2 [more]
Organism: Mouse
Tissue: Brain
Microvascular Disease in Chronic Thromboembolic Pulmonary Hypertension: Hemodynamic Phenotyping and Histomorphometric Assessment
Circulation (American Heart Association) Austria, Germany, France, Hungary, 03 January 2020
Cardiology
Key words: Chronic Thromboembolic Pulmonary Hypertension, Upstream Resistance, Pulmonary Vascular Resistance, Pulmonary Arterial Compliance, Microvascular Disease [more]
Organism: Human
Tissue: Lung
Anti-BAFF treatment interferes with humoral responses in a model of renal transplantation in rats
Transplantation (Wolters Kluwer) Germany, 01 January 2020
Transplantation Medicine
Organism: Rat
Tissue: Kidney
Effects of neoadjuvant FOLFIRONOX and gemcitabine-based chemotherapy on cancer cell survival and death in patients with pancreatic ductal adenocarcinoma
Oncotarget (Impact Journals) Germany, 31 December 2019
Oncology
Key words: autophagy, cell death, stroma, neoadjuvant therapy, prognosis [more]
Organism: Human
Tissue: Pancreas
Pathological State: Cancer
Protein Kinase B Inactivation Is Associated with Magnolol-Enhanced Therapeutic Efficacy of Sorafenib in Hepatocellular Carcinoma In Vitro and In Vivo
Cancers (MDPI) Taiwan, 30 December 2019
Oncology
Key words: Magnolol, Sorafenib, AKT, Hepatocellular carcinoma [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
High Fat Diet Suppresses Peroxisome Proliferator-Activated Receptors and Reduces Dopaminergic Neurons in the Substantia Nigra
International Journal of Molecular Sciences (MDPI) Taiwan, 27 December 2019
Neuroscience
Key words: high-fat diet (HFD), dopamine (DA), Parkinson disease (PD), peroxisome proliferator-activated receptor (PPAR) [more]
Organism: Mouse
Tissue: Brain
Nanoplatforms with Remarkably Enhanced Absorption in the Second Biological Window for Effective Tumor Thermo-Radiotherapy
ACS Applied Materials & Interfaces (ACS Publications) China, 25 December 2019
Nanomedicine
Key words: Copper sulfide, Gold, Second near-infrared window, Thermo-radiotherapy, Synergistic effect [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Dendritic cells treated with a prostaglandin I2 analog, iloprost, promote antigen-specific regulatory T cell differentiation in mice
International Immunopharmacology (Elsevier) Taiwan, 23 December 2019
Immunology
Key words: Allergic inflammation, Prostaglandin I2, mPEG-PLGA hydrogel, Regulatory T-cell, Tolerogenic dendritic cell, PD-L1 [more]
Organism: Mouse
Tissue: Lung
Heat-killed Mycobacterium paragordonae therapy exerts an anti-cancer immune response via enhanced immune cell mediated oncolytic activity in xenograft mice model
Cancer Letters (Elsevier) South Korea, 23 December 2019
Oncology
Key words: Cancer immnotherapy, Natural killer cells, Dendritic cells, Interleukin-12 [more]
Organism: Mouse
Tissue: Colon
Pathological State: Cancer
Switching to a Healthy Diet Prevents the Detrimental Effects of Western Diet in a Colitis-Associated Colorectal Cancer Model
Nutrients (MDPI) Austria, Germany, 23 December 2019
Oncology, Gastroenterology
Key words: inflammatory bowel disease, colitis-associated cancer, microbiome, western diet, vitamin D, non-alcoholic fatty liver disease, CYP24A1, Wnt pathway, aberrant crypt foci, mucosal regeneration [more]
Organism: Mouse
Tissue: Colon
Pathological State: Cancer
Visfatin Mediates Malignant Behaviors through Adipose-Derived Stem Cells Intermediary in Breast Cancer
Cancers (MDPI) Taiwan, 20 December 2019
Oncology
Key words: Breast cancer, Visfatin, Adipose-derived stem cells (ADSCs), GDF15 [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
Modulating Macrophage Phenotype by Sustained MicroRNA Delivery Improves Host‐Implant Integration
Advanced Healthcare Materials (Wiley) Singapore, USA, The Netherlands, 18 December 2019
Tissue Engineering
Key words: Electrospinning, Fibrous capsule formation, Gene silencing, RNA interference, Tissue engineering [more]
Organism: Mouse
Rhubarb-evoke Mucus Secretion through Aggregation and Degranulation of Mast cell in the colon of Rat: in vivo and ex vivo studies
Scientific Reports (Nature) China, 18 December 2019
Gastroenterology
Key words: Gastroenterology, Physiology
Assembly of vascular smooth muscle cells in 3D aggregates provokes cellular quiescence
Experimental Cell Research (Elsevier) Germany, 16 December 2019
Tissue Engineering
Key words: TGF, Vascular smooth muscle cells, Differentiation, 3D culture [more]
Organism: Human
Cell Line: HUASMCs
Effects of Circadian Rhythm Disorder on the Hippocampus of SHR and WKY Rats
Neurobiology of Learning and Memory (Elsevier) China, 16 December 2019
Neuroscience
Key words: Circadian rhythm disorder, Hypertension, Cognition, Hippocampus [more]
Organism: Rat
Tissue: Brain
Pathological State: Circadian Rhythm Disorder