Customer Publications (A total of 2312 papers published)
miR-103/107 prolong Wnt/β-catenin signaling and colorectal cancer stemness by targeting Axin2
Scientific Reports (Nature) Taiwan, 04 July 2019
Oncology
Key words: Colon cancer, Metastasis [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Entrapment of N-Hydroxyphthalimide Carbon Dots in Different Topical Gel Formulations: New Composites with Anticancer Activity
Pharmaceutics (MDPI) Romania, 01 July 2019
Oncology
Key words: composite, N-hydroxyphthalimide, carbon dots, polymer gels, antitumoral activity [more]
Organism: Human
Cell Line: MDA-MB-231 cells
Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons
EBioMedicine (THE LANCET) Japan, 29 June 2019
Neuroscience
Key words: Amyotrophic lateral sclerosis (ALS), Fused in sarcoma (FUS), Axon branching, Fos-B, Nerve organoid, Human-induced pluripotent stem cell (hiPSC)-derived motor neuron [more]
Organism: Human
Tissue: Spinal Cord
Pathological State: Amyotrophic Lateral Sclerosis
Fbxw7 increases CCL2/7 in CX3CR1hi macrophages to promote intestinal inflammation
The Journal of Clinical Investigation (American Society for Clinical Investigation) China, 27 June 2019
Immunology
Organism: Mouse
Tissue: Colon
Pathological State: Colitis
Amelioration of Experimentally Induced Arthritis by Reducing Reactive Oxygen Species Production through the Intra-Articular Injection of Water-Soluble Fullerenol
Nanomaterials (MDPI) China, Taiwan, 23 June 2019
Nanomedicine
Key words: experimental arthritis, intra-articular injection, reactive oxygen species, rheumatoid arthritis, water-soluble fullerenol [more]
Organism: Rat
Tissue: Bone, Connective Tissue
Pathological State: Rheumatoid Arthritis
Cytotoxic T-cells and their activation status are independent prognostic markers in meningiomas
Clinical Cancer Research (AACR Publications) Germany, 21 June 2019
Immunology, Oncology
Key words: Clinically aggressive meningioma, T-cell infiltration, primary and recurrent tumors TILs, PD-1 [more]
Organism: Human
Tissue: Brain
Pathological State: Cancer
Differential expression of Plg-RKT and its effects on migration of proinflammatory monocyte and macrophage subsets
Blood (American Society of Hematology) Austria, USA, 20 June 2019
Cardiology
Organism: Human
Tissue: Adipose Tissue
Specific inhibition of the classical complement pathway prevents C3 deposition along the dermal-epidermal junction in bullous pemphigoid
Journal of Investigative Dermatology (Elsevier) Austria, USA, 20 June 2019
Dermatology
Gasdermin D protects against noninfectious liver injury by regulating apoptosis and necroptosis
Cell Death & Disease (Nature) USA, China, 17 June 2019
Hepathology
Key words: Cell death and immune response, Innate immunity [more]
Organism: Mouse
Tissue: Liver
Pathological State: Liver Injury
C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice
Nature Communications Biology (Nature) The Netherlands, Germany, 14 June 2019
Oncology
Key words: Cancer metabolism, Cell growth [more]
Organism: Mouse
Tissue: Bone Marrow
Fc glycan-mediated regulation of placental antibody transfer
CELL (Cell Press) USA, Belgium, 13 June 2019
Reproductive Medicine, Immunology
Key words: antibody functionality, antibody glycosylation, trans-placental transfer, maternal vaccination, ADCC, neonatal immunology [more]
Organism: Human
Tissue: Placenta
The PPARγ Agonist Rosiglitazone Suppresses Syngeneic Mouse SCC (Squamous Cell Carcinoma) Tumor Growth through an Immune-Mediated Mechanism
Molecules (MDPI) USA, 11 June 2019
Oncology, Immunology
Key words: peroxisome proliferator activated receptor gamma, rosiglitazone, T-cells, myeloid cells, anti-tumor immunity [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Optimisation of multiplex immunofluorescence for a non-spectral fluorescence scanning system
Journal of Immunological Methods (Elsevier) Australia, 08 June 2019
Medical Imaging
Key words: Fluorescence microscopy, Imaging, Immunohistochemistry, T cells, Colorectal [more]
Organism: Human
Tissue: Colon
Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis
Nature (Nature) South Africa, USA, Kenya, Mexico, UK, Denmark, 05 June 2019
Immunology
Key words: Innate lymphoid cells, Tuberculosis [more]
Organism: Human
Tissue: Lung
Pathological State: Tuberculosis
Role of the PI3K‑mTOR autophagy pathway in nerve damage in rats with intermittent hypoxia‑aggravated whole brain ischemia
Molecular Medicine Reports (Spandidos Publications) China, 04 June 2019
Neuroscience
Organism: Rat
Tissue: Brain
Pathological State: Cerebral Ischemia
Heat-killed Mycobacterium tuberculosis prime-boost vaccination induces myeloid-derived suppressor cells with spleen dendritic cell-killing capability
The Journal of Clinical Investigation (American Society for Clinical Investigation) Germany, South Africa, 04 June 2019
Immunology
Organism: Mouse
Cell Line: BM-MDSCs and BM-DCs cell
Abnormal expression of b10 cell frequencies: possible relation to pathogenesis and disease severity of aplastic anemia
Revista da Associação Médica Brasileira (SciELO Brasil) China, 03 June 2019
Hematology
Key words: Anemia, Aplastic, B-Lymphocytes, Regulatory, Interleukin-10 [more]
Organism: Human
Cell Line: Bone marrow-derived mononuclear cells
Lysine 68 acetylation directs MnSOD as a tetrameric detoxification complex versus a monomeric tumor promoter
Nature Communications (Nature) USA, South Korea, 03 June 2019
Oncology
Key words: Breast cancer, Cancer, Enzyme mechanisms [more]
Organism: Mouse
Tissue: Breast
Pathological State: Cancer
Micro RNA‐133 Suppresses ZFHX 3‐dependent Atrial Remodeling and Arrhythmia
Acta Physiologica (Wiley) Taiwan, 01 June 2019
Cardiology
Key words: atrial ectopy, cardiac remodelling, connexin43, MicroRNA‐133, Wnt/calcium signalling, ZFHX3 [more]
Organism: Mouse
Tissue: Heart
Pathological State: Arrhythmia
AIF-regulated oxidative phosphorylation supports lung cancer development
Cell Research (Nature) China, Austria, France, Germany, Canada, Belgium, Sweden, 27 May 2019
Oncology
Key words: Mechanisms of disease, Non-small-cell lung cancer [more]
Organism: Mouse
Tissue: Lung
Pathological State: Cancer
Cancer Stem-Cell Marker CD44v9-Positive Cells Arise From Helicobacter pylori–Infected CAPZA1-Overexpressing Cells
Cellular and Molecular Gastroenterology and Hepatology (Elsevier) Japan, 27 May 2019
Oncology, Microbiology
Key words: Autophagy, CagA, Cancer Stem Cells, CD44v9, Eradication Therapy [more]
Organism: Human
Tissue: Stomach
Pathological State: Cancer
LINGO-1 deficiency promotes nerve regeneration through reduction of cell apoptosis, inflammation, and glial scar after spinal cord injury in mice
Experimental Neurology (Elsevier) China, 25 May 2019
Neuroscience
Key words: LINGO-1 knockout, Spinal cord injury, Cell apoptosis, Inflammation, Glial scar, Nerve regeneration [more]
Organism: Mouse
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer’s Disease Patients
Cell Stem Cell (Cell Press) USA, 23 May 2019
Neuroscience
Key words: human neurogenesis, adult neurogenesis, neural stem cells, neurogenesis in aging, cognitive dysfunction, aging, Alzheimer’s disease [more]
Organism: Human
Tissue: Brain
Pathological State: Alzheimer's Disease
Near-Infrared Fluorescent Endoscopic Image-guided Photothermal Ablation Therapy of Colorectal Cancer using Dual-modal Gold Nanorods Targeting Tumor Infiltrating Innate Immune Cells in Transgenic TS4 CRE/APCloxΔ468 Mouse Model
ACS Applied Materials & Interfaces (ACS Publications) USA, 22 May 2019
Oncology
Key words: colon cancer, endoscopic image-guided therapy, nanomedicine, interventional oncology, photothermal therapy [more]
Organism: Mouse
Tissue: Colon
Pathological State: Polyps
High Activation Of STAT5A Drives Peripheral T-Cell Lymphoma And Leukemia
Haematologica (The Ferrata Sorti Foundation) Austria, Czech Republic, Germany, Canada, 21 May 2019
Oncology
Key words: Hematopoiesis, Lymphocytes, Lymphoproliferative Disorders, PTCLSTAT5 [more]
Organism: Mouse
Tissue: Lymphoid Tissue
Pathological State: Cancer
The effect of 808 nm and 905 nm wavelength light on recovery after spinal cord injury
Scientific Reports (Nature) Czech Republic, USA, 21 May 2019
Regenerative Medicine
Key words: Spinal cord diseases, Spinal cord injury [more]
Organism: Rat
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Growth and cellular patterning during fetal human inner ear development studied by a correlative imaging approach
BMC Developmental Biology (Springer) Austria, 20 May 2019
Developmental Biology
Organism: Human
Tissue: Bone
Nano-formulated Curcumin (LipodisqTM) modulates the local inflammatory response, reduces glial scar and preserves the white matter after spinal cord injury in rats
Neuropharmacology (Elsevier) Czech Republic, 17 May 2019
Nanomedicine
Key words: Spinal cord injury, Nanocurcumin, Inflammatory response, Neuroregeneration, Astrogliosis, Axonal growth [more]
Organism: Mouse
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Amentoflavone Effectively Blocked the Tumor Progression of Glioblastoma via Suppression of ERK/NF-B Signaling Pathway
The American Journal of Chinese Medicine (World Scientific) Taiwan, 17 May 2019
Oncology
Key words: Amentoflavone, Glioblastoma, Anticancer, ERK, NF-κB [more]
Organism: Mouse
Tissue: Xenograft Tumor, Liver
Pathological State: Cancer
Potential Effects of CXCL9 and CCL20 on Cardiac Fibrosis in Patients with Myocardial Infarction and Isoproterenol-Treated Rats
Journal of Clinical Medicine (MDPI) Taiwan, 11 May 2019
Cardiology
Key words: myocardial infarction, cardiac fibrosis, CXCL9, CCL20, isoproterenol [more]
Organism: Rat
Tissue: Heart
Pathological State: Cardiac Fibrosis
In vitro biological response of cancer and normal tissue cells to proton irradiation not affected by an added magnetic field
Radiotherapy and Oncology (Elsevier) The Netherlands, 11 May 2019
Oncology
Key words: Protons, MRI, Tumor, Normal tissue, Organoids [more]
Organism: Human
Cell Line: Human embryonic kidney cells (HEK293) and human lung adenocarcinoma cells (A549)
Effects of Hydroxychloroquine on the Human Placenta–Findings from In Vitro Experimental Data and a Systematic Review
Reproductive Toxicology (Elsevier) UK, 10 May 2019
Reproductive Medicine
Key words: Hydroxychloroquine, Placenta, TLRs, TLR 7, TLR 9, Inflammation, Toxicology, Safety, Pregnancy, SLEAPS [more]
Organism: Human
Tissue: Placenta
Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance
CELL (Cell Press) USA, Sweden, 09 May 2019
Immunology
Key words: HIV vaccine, non-human primates, rhesus macaque genome, FNA, GC- TFH, memory B cells, somatic hypermutation, affinity maturation, immune complexes [more]
Organism: Mouse
Tissue: Lymphoid Tissue
Pathological State: HIV Infection
Multimodal [18F]FDG PET/CT is a direct readout for inflammatory bone repair: a longitudinal study in TNFα transgenic mice
Journal of Bone and Mineral Research (Wiley) Austria, 07 May 2019
Osteology
Key words: µPET/CT, 18F‐FDG, 18F‐NaF, bone healing, experimental arthritis, TNF blockade [more]
Organism: Human
Tissue: Bone, Connective Tissue
Directional Topography Influences Adipose Mesenchymal Stromal Cell Plasticity: Prospects for Tissue Engineering and Fibrosis
Stem Cells International (Hindawi Publishing Corporation) The Netherlands, Brazil, China, 05 May 2019
Stem Cell Research
Organism: Human
Cell Line: Adipose tissue derived stromal cells (ADSC)
Endoplasmic reticulum stress is involved in stress-induced hypothalamic neuronal injury in rats via the PERK-ATF4-CHOP and IRE1-ASK1-JNK pathways
Frontiers in Cellular Neuroscience (Frontiers Media S.A.) China, 03 May 2019
Neuroscience
Key words: hypothalamus, stress, neuronal injury, PERK-ATF4-CHOP pathway, IRE1-ASK1-JNK pathway [more]
Organism: Rat
Tissue: Brain
Pathological State: Brain Injury
CD11b+ cells markedly express the itch cytokine interleukin‐31 in polymorphic light eruption
British Journal of Dermatology (Wiley) Austria, 03 May 2019
Dermatology
Organism: Human
Tissue: Skin
Positive PD‑L1 expression is predictive for patients with advanced EGFR wild‑type non‑small cell lung cancer treated with gemcitabine and cisplatin
Oncology Letters (Spandidos Publications) China, 02 May 2019
Oncology
Key words: programmed death ligand-1, checkpoint, immunotherapy, non-small cell lung cancer, prognosis [more]
Organism: Human
Tissue: Lung
Pathological State: Cancer
Exosomal transfer of bone marrow mesenchymal stem cells-derived miR340 attenuates endometrial fibrosis
Biology Open (The Company of Biologists) China, 01 May 2019
Stem Cell Research
Organism: Rat
Tissue: Uterus
Pathological State: Endometriosis
An improved method of culturing somatotropic cells from rat adenohypophysis
Tissue and Cell (Elsevier) China, 30 April 2019
Biological Methods
Key words: Pericytes, Improved method, Primary culture, Somatotropic cells [more]
Organism: Rat
Cell Line: Pericytes
Promyelocytic leukemia zinc finger is involved in the formation of deep layer cortical neurons
Journal of Biomedical Science (Springer) Taiwan, 26 April 2019
Neuroscience
Key words: Promyelocytic leukemia zinc finger, Plzf, luxoid mice, Cortical neuron [more]
Organism: Mouse
Tissue: Brain
Exercise Alleviates Osteoporosis in Rats with Mild Chronic Kidney Disease by Decreasing Sclerostin Production
International Journal of Molecular Sciences (MDPI) Taiwan, 25 April 2019
Osteology, Nephrology
Key words: exercise, chronic kidney disease, osteoporosis, sclerostin, chronic kidney disease–mineral bone disorder [more]
Organism: Rat
Tissue: Bone
Pathological State: Kidney Disease
Wound Age Estimation by Neutrophil Migration Distance.
Fa yi xue za zhi (Europe PMC) China, 25 April 2019
Immunology
Th2-TRMs maintain life-long allergic memory in experimental asthma in mice
Frontiers in Immunology (Frontiers Media S.A.) Austria, 24 April 2019
Immunology
Organism: Mouse
Tissue: Lung
Pathological State: Asthma
YWHAE promotes proliferation, metastasis, and chemoresistance in breast cancer cells
Kaohsiung Journal of Medical Sciences (Wiley) Taiwan, 18 April 2019
Oncology
Key words: 14‐3‐3ε, breast cancer, chemoresistance, YWHAE [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
Toll‑like receptor 4 plays a tumor‑suppressive role in cutaneous squamous cell carcinoma
International Journal of Oncology (Spandidos Publications) Japan, 17 April 2019
Oncology
Key words: Toll-like receptor 4, cutaneous squamous cell carcinoma, differentiation, CD44, migration, invasion, filopodia [more]
Organism: Human
Tissue: Skin
Pathological State: Cancer
Functional CD3+ CD8+ PD-1-T cells accumulation and PD-L1 expression increases during tumor invasion in DCIS of the breast
Clinical Breast Cancer (Elsevier) China, USA, 16 April 2019
Oncology
Key words: DCIS, Opal technique PDl-1, PD-1, immune, microenvironment [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
Low cd8+ t cell infiltration and high pd-l1 expression are associated with level of cd44+/cd133+ cancer stem cells and predict an unfavorable prognosis in pancreatic cancer
Cancers (MDPI) Taiwan, 15 April 2019
Oncology
Key words: pancreatic cancer, T cells, cancer stem cells, CD8, PD-L1, CD44, CD133, immunotherapy [more]
Organism: Human
Tissue: Pancreas
Pathological State: Cancer
Metastatic Colorectal Cancer Rewrites Metabolic Program Through a Glut3-YAP-dependent Signaling Circuit
Theranostics (Ivyspring) Taiwan, 13 April 2019
Oncology
Key words: cancer metabolism, colorectal cancer, glucose transporter, metastasis, YAP [more]
Organism: Mouse
Tissue: Xenograft Tumor, Lung
Pathological State: Cancer
Interrelations of Sphingolipid and Lysophosphatidate Signaling With Immune System in Ovarian Cancer
Computational and Structural Biotechnology Journal (Elsevier) Austria, Germany, Belgium, Switzerland, Canada, 10 April 2019
Oncology
Key words: Sphingolipid/lysophosphatidate system, On-site immune response, Patient-specific expression data sets, Integrative analysis algorithm, Patient stratification, From systems biology to systems medicine [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
Au Nanoparticles with Enzyme-Mimicking Activities Ornamented ZIF-8 for Highly Efficient Photodynamic Therapy
Biomaterials Science (Royal Society of Chemistry) China, 04 April 2019
Nanomedicine
Key words: AuNPs nanozyme, nano metal-organic frameworks, tumor hypoxia, photodynamic therapy [more]
Organism: Mouse
Tissue: Breast
Pathological State: Cancer
Associations between hepatitis etiology and immune cell infiltration in or around hepatocellular carcinoma
Cancer Research (AACR Publications) USA, 03 April 2019
Oncology, Virology
Organism: Human
Tissue: Liver
Pathological State: Cancer
The sodium–glucose co-transporter 2 inhibitor empagliflozin attenuates cardiac fibrosis and improves ventricular hemodynamics in hypertensive heart failure rats
Cardiovascular Diabetology (Springer) Taiwan, 01 April 2019
Cardiology
Key words: SGLT2 inhibitor, Empagliflozin, Hypertensive, Heart failure, Cardiac fibrosis, Hemodynamics, High-fat, PPARα, ACADM [more]
Organism: Rat
Tissue: Heart
Pathological State: Cardiac Fibrosis, Heart Failure
Novel CHK1 inhibitor MU380 exhibits significant single-agent activity in TP53-mutated chronic lymphocytic leukemia cells
Haematologica (Ferrata Storti Foundation) Czech Republic, 01 April 2019
Oncology
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Antrodia cinnamomea induces anti-tumor activity by inhibiting the STAT3 signaling pathway in lung cancer cells
Scientific Reports (Nature) Taiwan, USA, Malaysia, 26 March 2019
Oncology
Key words: Drug development, Lung cancer [more]
Organism: Mouse
Tissue: Lung
PIP4K2A as a negative regulator of PI3K in PTEN-deficient glioblastoma
Journal of Experimental Medicine (Rockefeller University Press) South Korea, China, USA, 21 March 2019
Oncology, Cell Biology
Key words: Solid Tumors, Neuroscience [more]
Organism: Human
Tissue: Brain
Pathological State: Cancer
Designing pH-Triggered Drug Release Iron Oxide Nanocomposites for MRI Guided Photothermal-Chemoembolization Therapy of Liver Orthotopic Cancer
Biomaterials Science (Royal Society of Chemistry) China, 19 March 2019
Nanomedicine
Key words: pH-Triggered Drug Release, Iron Oxide Nanocomposites, MRI, Photothermal-Chemoembolization Therapy, Liver Orthotopic Cancer [more]
Organism: Rat
Tissue: Liver
Pathological State: Cancer
γδT cells suppress liver fibrosis via strong cytolysis and enhanced NK cell-mediated cytotoxicity against hepatic stellate cells
Frontiers in Immunology (Frontiers Media S.A.) China, Germany, Belgium, USA, 15 March 2019
Immunology
Key words: fibrosis, γδT cell, NKp46, cytotoxicity, γδT1, γδT17, CD137, cell crosstalk [more]
Organism: Mouse
Tissue: Liver
Pathological State: Liver Fibrosis
Traffic-related particulate matter exposure induces nephrotoxicity in vitro and in vivo
Free Radical Biology and Medicine (Elsevier) Taiwan, 14 March 2019
Toxicology
Key words: Nephrotoxicity, Autophagy, Apoptosis, Endoplasmic reticulum stress [more]
Organism: Rat
Tissue: Kidney
ErbB3 Ligand Heregulin1 Is a Major Mitogenic Factor for Uncontrolled Lung Cancer Cell Proliferation
Neoplasia (Elsevier) China, 02 March 2019
Oncology
Key words: ErbB3, Heregulin1, Lung Cancer [more]
Organism: Human
Tissue: Lung
Pathological State: Cancer
Sulfasalazine could modulate the CD44v9‐xCT system and enhance cisplatin‐induced cytotoxic effects in metastatic bladder cancer
Cancer Science (NCBI) Japan, 01 March 2019
Oncology
Key words: bladder cancer, CD44v9, cisplatin, metastasis, sulfasalazine [more]
Organism: Mouse
Tissue: Lung
Pathological State: Cancer
Expression of the neonatal Fc-receptor in placental-fetal endothelium and in cells of the placental immune system
Placenta (Elsevier) Austria, 28 February 2019
Reproductive Medicine
Key words: Human placenta, FcRn, syncytiotrophoblast, placental-fetal endothelial cells, placental macrophages, IgG transport [more]
Organism: Human
Tissue: Placenta
High-risk human papillomavirus oncogenes disrupt the Fanconi anemia DNA repair pathway by impairing localization and de-ubiquitination of FancD2
PLoS Pathogens (PLOS) USA, 28 February 2019
Virology
Key words: Immunoblotting, Oncogenes, DNA repair, Phosphorylation, Human papillomavirus, HPV-16, Cell signaling, Small interfering RNAs [more]
Organism: Human
Pathological State: HPV Infection
Cell Line: Primary human foreskin keratinocytes (HFKs)
Metabolic cross-talk between human bronchial epithelial cells and internalized Staphylococcus aureus as a driver for infection
Molecular and Cellular Proteomics (American Society for Biochemistry and Molecular Biology) Germany, The Netherlands,, 26 February 2019
Immunology
Key words: Staphylococcus aureus, in vivo proteomics, population heterogeneity, persister, bronchial epithelial cells, Apoptosis*, Autophagy Bacteria, Energy metabolism, Host-Pathogen Interaction, Infectious disease [more]
Organism: Human
Pathological State: Staphylococcus aureus Infection
Cell Line: Bronchial epithelial cells
Ligase 3–mediated end-joining maintains genome stability of human embryonic stem cells
The FASEB Journal (FASEB) Czech Republic, USA, 26 February 2019
Stem Cell Research
Key words: base excision repair, PARP1, 53BP1, pluripotent stem cells, alternative DNA end-joining [more]
Organism: Human
Cell Line: Human embryonic stem cells
Higher CXCL16 exodomain is associated with aggressive ovarian cancer and promotes the disease by CXCR6 activation and MMP modulation
Scientific Reports (Nature) USA, 21 February 2019
Oncology
Key words: Cancer, Ovarian cancer [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
State-of-the-Art of Profiling Immune Contexture in the Era of Multiplexed Staining and Digital Analysis to Study Paraffin Tumor Tissues
Cancers (MDPI) USA, 20 February 2019
Medical Image Analysis
Key words: immune profiling, cancer tissues, multiplexed methodologies, image analysis, spatial analysis
Long noncoding RNA AOC4P regulates tumor cell proliferation and invasion by epithelial–mesenchymal transition in gastric cancer
Therapeutic Advances In Gastroenterology (SAGE Journals) China, 19 February 2019
Oncology
Key words: AOC4P, long noncoding RNAs, metastasis, prognosis, stomach neoplasm [more]
Organism: Human
Tissue: Stomach
Pathological State: Cancer
B-type natriuretic peptide enhances fibrotic effects via matrix metalloproteinase-2 expression in the mouse atrium in vivo and in human atrial myofibroblasts in vitro
Translational Research (Elsevier) Taiwan, 19 February 2019
Cardiology
Key words: B-type natriuretic peptide, atrial fibrillation, matrix metalloproteinase [more]
Organism: Mouse
Tissue: Heart
SOX17 overexpression sensitizes chemoradiation response in esophageal cancer by transcriptional down-regulation of DNA repair and damage response genes
Journal of Biological Methods (Springer) Taiwan, 18 February 2019
Oncology
Key words: SOX17, Transcription regulation, Resistance, DNA repair, Concurrent chemoradiation therapy, Esophageal cancer [more]
Organism: Human, Mouse
Tissue: Colon, Xenograft Tumor
Pathological State: Cancer
Ultralong circulating choline phosphate liposomal nanomedicines for cascaded chemo-radiotherapy
Biomaterials Science (Royal Society of Chemistry) China, 14 February 2019
Nanomedicine
Key words: Cascaded chemo-radiotherapy, hypoxia-activated therapy, tumor hypoxia, ultralong circulating liposome [more]
Organism: Mouse
Tissue: Allograft Tumor
Pathological State: Cancer
The Accumulation and Effects of Liposomal Doxorubicin in Tissues Treated by Radiofrequency Ablation and Irreversible Electroporation in Liver: In Vivo Experimental Study on Porcine Models
CardioVascular and Interventional Radiology (Springer) Czech Republic, Israel, 13 February 2019
Hepathology
Key words: Liposomal doxorubicin, Radiofrequency ablation, Irreversible electroporation [more]
Organism: Pig
Tissue: Liver
Generation of human iPSCs from fetal prostate fibroblasts HPrF
Stem Cell Research (Elsevier) Czech Republic, 07 February 2019
Stem Cell Research
Key words: induced stem cells, iPSCs, prostate fibroblasts, HPrF [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Multimodal imaging guides surgical management in a preclinical spinal implant infection model
The Journal of Clinical Investigation (American Society of Clinical Investigation) USA, The Netherlands, 07 February 2019
Osteology
Organism: Mouse
Tissue: Spinal Cord
Pathological State: Spine implant infection
Fluorine-Modified Rutaecarpine Exerts Cyclooxygenase-2 Inhibition and Anti-inflammatory Effects in Lungs
Frontiers in Pharmacology (Frontiers Media S.A.) Taiwan, 07 February 2019
Pulmonology
Key words: Fluorine, Rutaecarpine, Cyclooxygenase-2, Anti-inflammatory Effects [more]
Organism: Mouse
Tissue: Whole Organism
Tumoral EHF predicts the efficacy of anti-PD1 therapy in pancreatic ductal adenocarcinoma
Journal of Experimental Medicine (Rockefeller University Press) China, USA, 07 February 2019
Oncology
Key words: EHF, anti-PD1 therapy, adenocarcinoma, pancreas [more]
Organism: Human
Tissue: Pancreas
Pathological State: Cancer
EphB2-dependent signaling promotes neuronal excitotoxicity and inflammation in the acute phase of ischemic stroke
Acta Neuropathologica (Springer) Germany, 05 February 2019
Neuroscience
Key words: EphB2, Ephrin-B2, Excitotoxicity, Inflammation, Ischemic stroke, NMDA [more]
Organism: Mouse
Tissue: Brain
Pathological State: Cerebral Ischemia
HIV-1 and SIV Infection Are Associated with Early Loss of Lung Interstitial CD4+ T Cells and Dissemination of Pulmonary Tuberculosis
Cell Reports (Cell Press) USA, 05 February 2019
Pulmonology
Key words: HIV-1, CD4+ T cells, cell death, tuberculosis, HIV/TB co-infection, lung, BAL [more]
Organism: Mouse
Tissue: Lung, Spleen
Pathological State: HIV Infection, SIV Infection, Tuberculosis
Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade
Immunity (Cell Press) USA, 05 February 2019
Oncology
Key words: cancer immunotherapy IFN-γ activation-induced cell death anti-CTLA-4 anti-PD-1 [more]
Organism: Mouse
Tissue: Allograft Tumor
Pathological State: Cancer
Hypoxic changes to the urothelium as a bystander of end-stage bladder disease
Journal of Pediatric Urology (Elsevier) UK, 05 February 2019
Urology
Key words: Neuropathic bladder, Hypoxia, Hypoxia-inducible factor1 alpha, Obstruction, Regenerative medicine [more]
Organism: Human
Pathological State: Neuropathy
Spatiotemporal Differences in Presentation of CD8 T Cell Epitopes during Hepatitis B Virus Infection
Journal of Virology (American Society for Microbiology) Singapore, Germany, Belgium, UK, 05 February 2019
Virology
Key words: antigen presentation, CD8 T cells, chronic hepatitis B patient, HBV DNA integration, HLA class I, liver, hepatitis B virus [more]
Organism: Human
Tissue: Liver
Pathological State: Hepatitis B Virus Infection
DSE regulates the malignant characters of hepatocellular carcinoma cells by modulating CCL5/CCR1 axis
American Journal of Cancer Research (NCBI) Taiwan, 01 February 2019
Oncology
Key words: Dermatan sulfate, DS epimerase, hepatocellular carcinoma, tumor infiltrated lymphocyte, CCL5 [more]
Organism: Human
Tissue: Liver
Pathological State: Cancer
Pathology of spontaneous and immunotherapy‐induced tumor regression in a murine model of melanoma
Pigment Cell and Melanoma Research (Wiley) USA, 31 January 2019
Oncology
Key words: melanoma, mouse models, B cells, neutrophils, Ly6B.2, histology, tumor regression, NETs [more]
Organism: Mouse
Tissue: Allograft Tumor
Pathological State: Cancer
COPD and asthma therapeutics for supportive treatment in organophosphate poisoning
Clinical Toxicology (Taylor and Francis) Germany, 30 January 2019
Toxicology
Key words: Organophosphate poisoning, nerve agents, PCLS, COPD, asthma [more]
Organism: Rat
Tissue: Lung
Sensory Neuropeptides and their Receptors Participate in Mechano-Regulation of Murine Macrophages
International Journal of Molecular Sciences (MDPI) Germany, 24 January 2019
Immunology
Key words: cyclic stretch, mechan-oregulation, murine macrophages, substance P, alpha-calcitonin gene-related peptide, neurokinin receptor, CGRP receptor, destabilized medial meniscus [more]
Organism: Mouse
Pathological State: Osteoarthritis
Cell Line: Bone Marrow-derived Macrophages
Multiple defects sensitize p53-deficient head and neck cancer cells to the WEE1 kinase inhibition
Molecular Cancer Research (AACR Publications) USA, 24 January 2019
Oncology
Key words: Head and neck cancer, WEE1, TP53, cell cycle, mitosis, replication stress, DNA damage [more]
Organism: Human
Cell Line: Primary fibroblast cells (HFF4), Head and neck cancer cell line UM-SCC-74a
Safe Nanocomposite‐Mediated Efficient Delivery of MicroRNA Plasmids for Autosomal Dominant Polycystic Kidney Disease (ADPKD) Therapy
Advanced Healthcare Materials (Wiley) Taiwan, 23 January 2019
Nanomedicine
Key words: ADPKD, microRNA, MR, I nanoparticles, plasmid DNA [more]
Organism: Mouse
Tissue: Kidney
Pathological State: Kidney Disease
Dynamic changes in intramedullary pressure 72 hours after spinal cord injury
Neural Regeneration Research (Publishing House of Neural Regeneration Research) China, 23 January 2019
Neuroscience
Key words: anesthetized, blood-spinal barrier, conscious, edema, hemorrhage, nerve regeneration, neural regeneration, pathological mechanism, pressure measurement, rabbit, secondary spinal cord injury, telemetry [more]
Organism: Rabbit
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Chronic thromboembolic pulmonary hypertension in Austria and Japan
The Journal of thoracic and cardiovascular surgery (Elsevier) Austria, Japan, 21 January 2019
Cardiology
Key words: Chronic thromboembolic pulmonary hypertension, pulmonary endarterectomy, balloon pulmonary angioplasty,
Transplantation of neural precursors generated from spinal progenitor cells reduces inflammation in spinal cord injury via NF-κB pathway inhibition
Journal of Neuroinflammation (Springer) Czech Republic, USA, 17 January 2019
Stem Cell Research
Key words: NF-κB, p65, Spinal cord injury, Stem cells transplantation, Inflammation, TNF-α, [more]
Organism: Rat
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease
Cancer Cell (Cell Press) Austria, Canada, UK, Australia, 14 January 2019
Oncology
Key words: ERBB, horizontal transmission, MHC class I, receptor tyrosine kinases, STAT3, Tasmanian devil, transmissible cancer, tumor vulnerability, systems biology xenograft [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Probiotic Lactobacillus spp. Act Against Helicobacter pylori-induced Inflammation
Journal of Clinical Medicine (MDPI) Taiwan, 14 January 2019
Microbiology
Key words: Helicobacter pylori, Lactobacillus, probiotic, inflammation [more]
Organism: Mouse
Tissue: Stomach
Pathological State: Helicobacter pylori Infection
Brain-Derived Neurotrophin and TrkB in Head and Neck Squamous Cell Carcinoma
International Journal of Molecular Sciences (MDPI) Austria, 11 January 2019
Oncology
Key words: epithelial–mesenchymal transition, vimentin, cytokeratin, p53 mutation, paraffin embedding, riboprobe [more]
Organism: Human
Tissue: Head and Neck
Pathological State: Cancer
An integrated characterization of contractile, electrophysiological, and structural cardiotoxicity of Sophora tonkinensis Gapnep. in human pluripotent stem cell-derived cardiomyocytes
Stem Cell Research & Therapy (BMC) China, 11 January 2019
Stem Cell Research
Key words: Cardiotoxicity, Sophora tonkinensis, hiPSC-CMs, Cardio-NLCS [more]
Organism: Human
Cell Line: Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)
Clinical significance of c-Met and phospho-c-Met (Tyr1234/1235) in ovarian cancer
Taiwanese Journal of Obstetrics and Gynecology (Elsevier) Taiwan, 09 January 2019
Oncology
Key words: c-Met, phospho-c-Met, Ovarian cancer [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
High-Throughput Synapse-Resolving Two-Photon Fluorescence Microendoscopy for Deep-Brain Volumetric Imaging In Vivo
eLife (eLife Sciences Publications) USA, 03 January 2019
Neuroscience
Key words: two-photon fluorescence microendoscopy, volumetric imaging, Bessel beam, hippocampus, lateral hypothalamus [more]
Organism: Mouse
Tissue: Brain
Genetic labeling reveals temporal and spatial expression pattern of D2 dopamine receptor in rat forebrain
Brain Structure and Function (Springer) China, 02 January 2019
Neuroscience
Key words: Drd2, Knockin rats, Olfactory bulb, Cerebral cortex, Hippocampus [more]
Organism: Mouse, Rat
Tissue: Brain
Abundance of the Organic Anion-transporting Polypeptide OATP4A1 in Early-Stage Colorectal Cancer Patients: Association With Disease Relapse
Applied Immunohistochemistry & Molecular Morphology (Ingentaconnect) Austria, 01 January 2019
Oncology
Key words: OATP4A1, SLCO4A1, automated microscopic imaging system, colorectal cancer, relapse [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Loss of the dystonia gene Thap1 leads to transcriptional deficits that converge on common pathogenic pathways in dystonic syndromes
Human Molecular Genetics (Oxford University Press) USA, 26 December 2018
Neuroscience
Key words: alleles, phenotype, dopamine, signal transduction, transcription, genetic basal ganglia dystonia homeostasis cytoskeleton embryo genes gliosis mice, knockout movement disorders rna, messenger synaptic transmission up-regulation (physiology) zinc fingers cerebellum mice transcription factor agonists antagonists haploinsufficiency nervous system development nestin protein torsion dystonia 6 loss of function mutation [more]
Organism: Mouse
Tissue: Brain
Effects of cylindrospermopsin on cultured immortalized human airway epithelial cells
Chemosphere (Elsevier) Czech Republic, Germany, 22 December 2018
Toxicology
Key words: Cyanobacteria, Cyanotoxin, HBE, Inhalation toxicity, MAPK [more]
Organism: Human
Cell Line: Human bronchial epithelial cell line (HBE) 16HBE14o-cells
Histo-genomics: digital pathology at the forefront of precision medicine
Diagnosis (De Gruyter) Canada, 20 December 2018
Pathology
Spatial mapping of myeloid cells and macrophages by multiplexed tissue staining
Frontiers in Immunology (Frontiers Media S.A.) USA, 14 December 2018
Immunology
Key words: FFPE, immunofluorescence, immunohistochemistry, macrophage, multiplex, myeloid, spatial profiling [more]
Organism: Human
Tissue: Colon, Tonsil
Pathological State: Cancer
Predominant Striatal Input to the Lateral Habenula in Macaques Comes from Striosomes
Current Biology (Cell Press) USA, Japan, 13 December 2018
Neuroscience
Key words: basal ganglia, dopamine, motivation, non-human primate, mood, learning, microstimulation [more]
Organism: Monkey
Tissue: Brain
Melanocyte-specific gene 1 promotes melanoma progression by enhancing the expression of Bcl-2
Oncology Letters (Spandidos Publications) China, 12 December 2018
Oncology
Key words: melanocyte-specific gene 1, melanoma, cell viability, apoptosis, Bcl-2 [more]
Organism: Human
Tissue: Skin
Pathological State: Cancer
The FAK inhibitor BI 853520 inhibits spheroid formation and orthotopic tumor growth in malignant pleural mesothelioma
Journal of Molecular Medicine (Springer) Austria, Germany, Hungary, 11 December 2018
Oncology
Key words: Mesothelioma, Focal adhesion kinase, Tyrosine kinase inhibitor, Angiogenesis, Spheroid formation, Orthotopic xenograft [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Anti-inflammatory compound curcumin and mesenchymal stem cells in the treatment of spinal cord injury in rats.
Acta Neurobiologiae Experimentalis (Nencki Institute of Experimental Biology) Czech Republic, USA, 05 December 2018
Regenerative Medicine
Key words: Spinal cord injury, human mesenchymal stem cells, curcumin, combined therapy, inflammatory response [more]
Organism: Rat
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Cell Line: Human mesenchymal stem cells (hMSCs)
The natural polyphenol curcumin induces apoptosis by suppressing STAT3 signaling in esophageal squamous cell carcinoma
Journal of Experimental & Clinical Cancer Research (Springer) China, 05 December 2018
Oncology
Key words: Curcumin, STAT3, Esophageal squamous cell carcinoma, Apoptosis, PDX model [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
CXCL5 as regulator of neutrophil function in cutaneous melanoma
Journal of Investigative Dermatology (Elsevier) Austria, Germany, Spain, 04 December 2018
Oncology, Dermatology
Organism: Mouse
Tissue: Lung, Xenograft Tumor
Pathological State: Cancer
Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression
The Journal of Clinical Investigation (American Society for Clinical Investigation) USA, China, 04 December 2018
Oncology
Key words: Genetics, Oncology, Prostate cancer [more]
Organism: Human
Tissue: Prostate
Pathological State: Cancer
Extracellular vesicles from mature dendritic cells (DC) differentiate monocytes into immature DC
Life Science () Germany, Austria, 03 December 2018
Immunology
Key words: Medical Research, Immunology [more]
Organism: Human, Mouse
Cell Line: Monocyte-derived dentritic cells
Elevated Serum Interleukin-8 Level Correlates with Cancer-Related Cachexia and Sarcopenia: An Indicator for Pancreatic Cancer Outcomes
Journal of Clinical Medicine (MDPI) Taiwan, 01 December 2018
Oncology
Key words: pancreatic cancer, cancer cachexia, sarcopenia, interleukin (IL)-1β, IL-6, IL-8, tumor necrosis factor (TNF)-α [more]
Organism: Human
Tissue: Pancreas
Pathological State: Cancer
Freshwater cyanotoxin cylindrospermopsin has detrimental stage-specific effects on hepatic differentiation from human embryonic stem cells
Toxicological Sciences (Oxford University Press) Czech Republic, 30 November 2018
Stem Cell Research
Key words: cylindrospermopsin, hepatic differentiation, human embryonic stem cells, liver, cyanotoxin [more]
Organism: Human
Cell Line: Human embryonic stem cell (hESCs)
Pterostilbene Attenuates Hexavalent Chromium-Induced Allergic Contact Dermatitis by Preventing Cell Apoptosis and Inhibiting IL-1β-Related NLRP3 Inflammasome Activation
Journal of Clinical Medicine (MDPI) Taiwan, 27 November 2018
Allergy Research
Key words: Hexavalent chromium, pterostilbene, endoplasmic reticulum stress, inflammatory cytokines, NLRP3 inflammasome, allergic contact dermatitis [more]
Organism: Mouse
Tissue: Skin
Pathological State: Dermatitis
ONECUT2 Is a Targetable Master Regulator of Lethal Prostate Cancer That Suppresses the Androgen Axis
Nature Medicine (Nature) USA, Taiwan, 26 November 2018
Oncology
Immune Cell and Cell Cluster Phenotyping, Quantitation, and Visualization Using In Silico Multiplexed Images and Tissue Cytometry
Cytometry Part A (Wiley) USA, 23 November 2018
Cytometry
Key words: immune cells, cell clusters, quantitative imaging, multiplexed histology, tissue cytometry, TissueFAXS in silico analysis, FFPE [more]
Organism: Mouse
Tissue: Spleen
Pathological State: Cancer
PD-L1 expression and the prognostic significance in gastric cancer: a retrospective comparison of three PD-L1 antibody clones (SP142, 28–8 and E1L3N)
Diagnostic Pathology (Springer) China, 21 November 2018
Oncology
Key words: Programmed cell death ligand 1, Immunohistochemistry, H-score, Multiplexed immunofluorescence [more]
Organism: Human
Tissue: Stomach
Pathological State: Cancer
MicroRNA-451a overexpression induces accelerated neuronal differentiation of Ntera2/D1 cells and ablation affects neurogenesis in microRNA-451a-/- mice
PLoS One (PLOS) Austria, 21 November 2018
Neuroscience
Key words: Neuronal differentiation, Neurites, Cell differentiation, Neurospheres, MicroRNAs, Neural networks, Fluorescence microscopy, Nestin [more]
Organism: Mouse
Tissue: Brain
Oxidative muscles have better mitochondrial homeostasis than glycolytic muscles throughout life and maintain mitochondrial function during aging
Aging (Impact Journals) USA, 18 November 2018
Physiology
Key words: Aging, glycolytic, mitochondria, oxidative, sarcopenia, skeletal muscle [more]
Organism: Mouse
Tissue: Muscle
Generation of human iPSCs from human prostate cancer-associated fibroblasts IBPi002-A
Stem Cell Research (Elsevier) Czech Republic, 16 November 2018
Stem Cell Research
Key words: induced stem cells, iPSCs, prostate fibroblasts, IBPi00-2 [more]
Organism: Human
Cell Line: Induced pluripotent cells (iPSCs)
Effect of dentin matrix components on the mineralization of human mesenchymal stromal cells
Tissue Engineering Part A (Mary Ann Liebert Inc.) The Netherlands, UK, 16 November 2018
Regenerative Medicine
Key words: dental pulp, dentin matrix, mesenchymal stromal cells, mineralization, tissue engineering, umbilical cord [more]
Organism: Human
Cell Line: Dental pulp stem cells (DPSCs), Adipose tissue derived stem cells (ASCs)
Hepatocellular carcinoma-targeted nanoparticles for cancer therapy
International Journal of Oncology (Spandidos Publications) Taiwan, 16 November 2018
Oncology
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Semi-Automated and Manual Methods for Counting Cells Expressing P75 Receptor in Endometriotic Lesions
International Conference on Science and Technology-Computer (ICST) () Indonesia, Austria, 12 November 2018
Cytometry
Key words: Observers, Immune system, Software, Lesions, Manuals, Biomedical imaging, Tools
Novel Protective Effects of Cistanche Tubulosa Extract Against Low-Luminance Blue Light-Induced Degenerative Retinopathy
Cellular Physiology and Biochemistry (Karger) Taiwan, 07 November 2018
Ophthalmology
Key words: Cistanche tubulosa extract • Blue light • Apoptosis • Retinal pigment epithelial cells [more]
Organism: Human
Cell Line: Retinal pigment epithelium cells (RPEs)
Increased frequency of systemic pro-inflammatory Vδ1+ γδ T cells in HIV elite controllers correlates with gut viral load
Scientific Reports (Nature) USA, 07 November 2018
Immunology, Virology
Key words: Chronic inflammation, Gammadelta T cells, HIV infections, Infection, Mucosal immunology [more]
Organism: Human
Tissue: Small Intestine
Pathological State: HIV Infection
Loss of BAP1 expression is associated with genetic mutation and can predict outcomes in gallbladder cancer
PLoS One (PLOS) Japan, USA, 05 November 2018
Oncology
Key words: DNA methylation, Small interfering RNAs, Polymerase chain reaction, Methylation, Mutation detection, Prognosis, DNA sequence analysis, Nonsense mutation [more]
Organism: Human
Pathological State: Cancer
Genetic ablation of NFAT5/TonEBP in smooth muscle cells impairs flow- and pressure-induced arterial remodeling in mice
The FASEB Journal (FASEB) Germany, 01 November 2018
Regenerative Medicine
Key words: hypertension, wall stress, transcriptome [more]
Organism: Mouse
Cell Line: Primary aterial smooth muscle cells, vascular smooth muscle cells (VSMCs )
Genetic ablation of NFAT5/TonEBP in smooth muscle cells impairs flow-and pressure-induced arterial remodeling in mice
The FASEB Journal (FASEB) Germany, 01 November 2018
Cardiology
Key words: hypertension, wall stress, transcriptome [more]
Organism: Mouse
Cell Line: Vascular Smooth Muscle Cells
Tissue and host species-specific transcriptional changes in models of experimental visceral leishmaniasis
Wellcome Open Research (Wellcome Open Research) UK, 29 October 2018
Parasitology
Key words: Leishmania, infection, host response, transcriptomics, immunopathology [more]
Organism: Mouse
Tissue: Spleen, Liver
Pathological State: Leishmaniasis
Azo-based small molecular hypoxia responsive theranostic for tumor-specific imaging and therapy
Journal of Controlled Release (Elsevier) China, India, South Korea, 28 October 2018
Oncology
Key words: molecular hypoxia, theranostic, tumor-specific imaging, [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
PI3K: A master regulator of brain metastasis‐promoting macrophages/microglia
GLIA (Wiley) Germany, 25 October 2018
Oncology
Key words: Astrocytes, BKM120, brain metastasis, macrophages, microglia, PI3K, RPPA [more]
Organism: Mouse
Pathological State: Cancer
Cell Line: Monocyte‐derived macrophages (MDMs)
Alteration of mesenchymal stem cells polarity by laminar shear stimulation promoting β-catenin nuclear localization
Biomaterials (Elsevier) Taiwan, 23 October 2018
Stem Cell Research
Key words: β-catenin, Cardiovascular, Laminar shear, Mesenchymal stem cells, Wnt [more]
Organism: Human
Cell Line: Human mesenchymal stem cells (hMSCs)
Gene expression profiling in a mouse model of Dravet syndrom
Experimental Neurology (Elsevier) USA, 19 October 2018
Neuroscience
Key words: Epilepsy, Epileptic encephalopathy, Gene expression, RNA-seq, Seizure, Voltage-gated sodium channel [more]
Organism: Mouse
Tissue: Brain
Pathological State: Dravet Syndrome
Kinin-B2 Receptor Activity in Skeletal Muscle Regeneration and Myoblast Differentiation
Stem Cell Reviews and Reports (Springer) USA, Brazil, 18 October 2018
Stem Cell Research
Key words: Mouse myoblast differentiation, Muscle repair, Kinin-B2 receptor, HOE-140 [more]
Organism: Mouse
Cell Line: Myoblast cell line - C2C12 Cells
Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting
CELL (Cell Press) Israel, Austria, Sweden, 11 October 2018
Cell Biology
Key words: immune systemsingle-cell RNA sequencinglungbasophilsalveolar macrophagescellular interactiondevelopmentsignaling [more]
Organism: Mouse
Tissue: Lung
Early Immunologic Response of Irreversible Electroporation versus Cryoablation in a Rodent Model of Pancreatic Cancer
Journal of Vascular and Interventional Radiology (Elsevier) USA, 11 October 2018
Immunology
Key words: irreversible electroporation, Cryoablation, Pancreatic Cancer [more]
Organism: Mouse
Pathological State: Cancer
Cell Line: PANC-2 (Pancreatic cancer cell line)
Transforming growth factor beta 1 mediates the low-frequency vertical vibration enhanced production of tenomodulin and type I collagen in rat Achilles tendon
PLoS One (PLOS) Taiwan, 11 October 2018
Cell Biology
Key words: Tendons, Collagens, Gene expression, Stiffness, Vibration, Mechanical properties, Enzyme-linked immunoassays, Polymerase chain reaction [more]
Organism: Rat
Accelerated Aging and Clearance of Host Anti-inflammatory Enzymes by Discrete Pathogens Fuels Sepsis
Cell Host and Microbe (Cell Press) USA, 10 October 2018
Immunology, Microbiology
Key words: glycosylation, sepsis, neuraminidase, Toll-like receptor 4, alkaline phosphatase, Ashwell-Morell receptor, lipopolysaccharide, inflammation [more]
Organism: Mouse
Tissue: Liver
Pathological State: Sepsis
Inhibition of AKT suppresses the initiation and progression of BRCA1-associated mammary tumors
International Journal of Biological Sciences (Ivyspring International Publisher) South Korea, China, 10 October 2018
Oncology
Key words: BRCA1, AKT, MK-2206, precision medicine [more]
Organism: Mouse
Tissue: Breast
Pathological State: Cancer
Extracellular domain of EpCAM enhances tumor progression through EGFR signaling in colon cancer cells
Cancer Letters (Elsevier) Taiwan, 01 October 2018
Oncology
Key words: Epithelial cell adhesion molecule, Regulated intramembrane proteolysis, β-catenin, HIF1α [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Age, but not short-term intensive swimming, affects chondrocyte turnover in zebrafish vertebral cartilage
The Journal of Life and Environmental Sciences (PeerJ) Taiwan, 01 October 2018
Osteology
Key words: Aging, Cartilage, Osteoarthritis, Tissue homeostasis, Chondrocyte [more]
Organism: Fish
Tissue: Spinal Cord
Gd-EOB-DTPA DCE-MRI biomarkers in a rabbit model of liver fibrosis
American Journal of Translational Research (e-Century Publishing Corporation) China, USA, 30 September 2018
Hepathology
Key words: Liver fibrosis, animal, magnetic resonance imaging, pathology [more]
Organism: Rabbit
Tissue: Liver
Pathological State: Liver Fibrosis, Liver Cirrhosis
Modified Ginseng Extract Induces Apoptosis in HepG2 Cancer Cells by Blocking the CXCL8-Mediated Akt/Nuclear Factor-κB Signaling Pathway
The American Journal of Chinese Medicine (World Scientific) South Korea, 27 September 2018
Oncology
Key words: Modified Regular Ginseng Extract, MRGX, C-X-C Motif Chemokine Ligand 8, Liver Cancer, Akt, Nuclear Factor-κB, Apoptosis [more]
Organism: Human
Pathological State: Cancer
Cell Line: HepG2 (Liver carcinoma cell line)
Development of Decellularized Cornea by Organic acid Treatment for Corneal Regeneration
Tissue Engineering Part A (Mary Ann Liebert Inc.) Taiwan, 22 September 2018
Regenerative Medicine
Key words: cornea, decellularized scaffold, extracellular matrix, xenograft, corneal transplantation. [more]
Organism: Rabbit
Tissue: Eye
ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific manner
PLoS One (PLOS) USA, 18 September 2018
Oncology
Key words: Telomeres, Cloning, Glioma cells, Glioma, DNA cloning, Immunoblotting, Vector cloning, Polymerase chain reaction [more]
Organism: Human
Pathological State: Cancer
Cell Line: Glioma cell lines (MOG-G-UVW, SF188, U-251 and UW479)
The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases
Science Signaling (American Association for the Advancement of Science) Czech Republic, Belgium, USA, Norway, 18 September 2018
Cell Biology
Key words: SHIP2, ERK activation, FGF receptors, Src kinases [more]
Organism: Rat, Human
Pathological State: Cancer
Cell Line: U2OS (Osteosarcoma cell line), RCS cells (Cultured rat chondrosarcoma cell line)
Activation of estrogen receptor alpha induces beiging of adipocytes
Molecular Metabolism (Elsevier) USA, 15 September 2018
Cell Biology
Key words: Beige adipocytes, Lipolysis, Estrogen receptor alpha (ERα), Obesity, Type II diabetes mellitus (T2DM) [more]
Organism: Mouse
Tissue: Adipose Tissue
Pathological State: Obesity, Diabetes
Cellular-scale probes enable stable chronic subsecond monitoring of dopamine neurochemicals in a rodent model
Communications Biology (Nature) USA,, 12 September 2018
Neuroscience
Key words: Diagnostic markers, Neurochemistry, Parkinson's disease, Sensors and probes [more]
Organism: Rat
Tissue: Brain
Synthetic α5β1 integrin ligand PHSRN is proangiogenic and neuroprotective in cerebral ischemic stroke
Biomaterials (Elsevier) Taiwan, 11 September 2018
Biological Materials
Key words: Stroke, Fibronectin, PHSRN, α5β1, Angiogensis, Neurogenesis, VEGF [more]
Organism: Rat
Tissue: Brain
Factor Xa inhibition by rivaroxaban regulates fibrogenesis in human atrialfibroblasts with modulation of nitric oxide synthesis and calciumhomeostasis
Journal of Molecular and Cellular Cardiology (Elsevier) Taiwan, 10 September 2018
Physiology
Key words: Fibroblasts, Fibrosis, Rivaroxaban, Protease-activated receptor, Atrial fibrillation, Stroke [more]
Organism: Rat
Tissue: Heart
Pathological State: Cardiac Fibrosis, Myocardial Ischemia
Phenethyl Isothiocyanate Inhibits In Vivo Growth of Xenograft Tumors of Human Glioblastoma Cells
Molecules (MDPI) Taiwan, 10 September 2018
Oncology
Key words: phenethyl isothiocyanate, apoptosis, xenograft, caspase, glioblastoma [more]
Organism: Mouse
Tissue: Liver, Xenograft Tumor
Pathological State: Cancer
Androgen receptor expression inversely correlates with immune cell infiltration in human epidermal growth factor receptor 2–positive breast cancer
European Journal of Cancer (Elsevier) The Netherlands, China, 09 September 2018
Oncology
Key words: Androgen receptor expression, HER2-positive metastatic breast cancer, Immune cell infiltration, Trastuzumab resistance [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
TLR7 agonist attenuates acetylcholine‐induced, Ca2+‐dependent ionic currents in swine tracheal submucosal gland cells
Experimental Physiology (Wiley) Japan, 08 September 2018
Physiology
Key words: CaCC, COPD, hypersecretion, R837, submucosal glands [more]
Organism: Pig, Human
Tissue: Lung, Spleen
Inhibitory control of prefrontal cortex by the claustrum
Neuron (Cell Press) USA, UK, Canada, 05 September 2018
Neuroscience
Key words: claustrum prefrontal NPY PV neocortex feed-forward inhibition microcircuit neurogliaform cell somatostatin interneuron VIP [more]
Organism: Mouse
Tissue: Brain
Oxidized Low-Density Lipoprotein-Deteriorated Psoriasis Is Associated with the Upregulation of Lox-1 Receptor and Il-23 Expression In Vivo and In Vitro
International Journal of Molecular Sciences (MDPI) Taiwan, 03 September 2018
Dermatology
Key words: oxLDL, LOX-1, psoriasis [more]
Organism: Mouse
Tissue: Skin
Pathological State: Psoriasis
Enhanced Sternal Healing via Platelet-Rich Plasma and Biodegradable Gelatin Hydrogel
Tissue Engineering Part A (Mary Ann Liebert Inc.) Japan, 01 September 2018
Regenerative Medicine
Organism: Rabbit
Tissue: Bone
Amentoflavone Inhibits Hepatocellular Carcinoma Progression Through Blockage of ERK/NF-ĸB Activation
in vivo: international journal of experimental and clinical pathophysiology and drug research (International Institute of Anticancer Research) Taiwan, 01 September 2018
Oncology
Key words: Amentoflavone, hepatocellular carcinoma, extracellular signal-regulated kinase, nuclear factor-kappaB, bioluminescence imaging. [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
The tree shrew cerebellum atlas: Systematic nomenclature, neurochemical characterization and afferent projections
Journal of Comparative Neurology (Wiley) China, 29 August 2018
Neuroscience
Key words: cerebellar nuclei, lobule fissure, inferior olive, Purkinje cell, calbindin, RRID: AB_476894 [more]
Organism: Tree Shrew
Tissue: Brain
Focused Ultrasound-Induced Blood-Brain Barrier Opening Enhances GSK-3 Inhibitor Delivery for Amyloid-Beta Plaque Reduction
Scientific Reports (Nature) Taiwan, 27 August 2018
Neuroscience
Key words: Alzheimer's disease, eBiomedical engineering, Blood–brain barrier, Drug delivery, Translational research, GSK-3, Amyloid-Beta Plaque [more]
Organism: Mouse
Tissue: Brain
Pathological State: Alzheimer's Disease
Role of the orexin 2 receptor in palatable-food consumption-associated cardiovascular reactivity in spontaneously hypertensive rats
Scientific Reports (Nature) Taiwan, 23 August 2018
Cardiology
Key words: Hypertension, Hypothalamus [more]
Organism: Rat
Tissue: Brain
NFAT5 isoform C controls biomechanical stress responses of vascular smooth muscle cells
Frontiers in Physiology (Frontiers Media S.A.) Germany, 23 August 2018
Cardiology
Key words: NFAT5, TonEBP, hypertension, transcriptional regulation, vascular smooth muscle cells, wall stress [more]
Organism: Human
Cell Line: Human arterial smooth muscle cells (HUASMCs)
Photoperiodic Flower Mimicking Metallic Nanoparticles for Image-Guided Medicine Applications
ACS Applied Materials & Interfaces (ACS Publications) USA, 22 August 2018
Radiotherapy
Key words: metallic nanoparticles, radiosensitizers, image-guided radiotherapy, radiation, cancer therapy [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Optimization of an Anti-NMDA Receptor Autoantibody Diagnostic Bioassay
Circulation (NCBI) Taiwan, Denmark, Sweden, 22 August 2018
Neuroscience
Key words: Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis, autoantibody (autoAb), autoimmune encephalitis, schizophrenia, diagnostic test, fluorescein isothiocyanate (FITC), Alexa Fluor 488, antigen (Ag) [more]
Organism: Human
Pathological State: Encephalitis
Lack of DNA damage response at low radiation doses in adult stem cells contributes to organ dysfunction
Clinical Cancer Research (AACR Publications) The Netherlands, 22 August 2018
Oncology
Key words: DNA Damage, Radiation, Stem Cells, Organ Dysfunction, Radiotherapy [more]
Organism: Mouse
Tissue: Thyroid, Salivary Gland
Striatal Microstimulation Induces Persistent and Repetitive Negative Decision-Making Predicted by Striatal Beta-Band Oscillation
Neuron (Cell Press) USA, 22 August 2018
Neuroscience
Key words: approach-avoidance conflict, basal ganglia, beta oscillation, caudate nucleus, cost-benefit decisions, emotion, macaque, motivation, primate, value judgment [more]
Organism: Pig, Human
Tissue: Brain
Modified Methacrylate Hydrogels Improve Tissue Repair after Spinal Cord Injury
International Journal of Molecular Sciences (MDPI) Czech Republic, 22 August 2018
Regenerative Medicine
Key words: spinal cord injury, hydrogel, connective tissue, neurofilaments, locomotor test, plantar test [more]
Organism: Rat
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Secreted products of oral bacteria and biofilms impede mineralization of apical papilla stem cells in TLR-, species-, and culture-dependent fashion
Scientific Reports (Nature) The Netherlands, 21 August 2018
Immunology, Microbiology
Key words: Mesenchymal stem cells, Oral diseases, biofilms [more]
Organism: Human
Cell Line: SCAP (Stem cells from apical papilla)
Cbl-b deficiency provides protection against UVB-induced skin damage by modulating inflammatory gene signature
Cell Death & Disease (Nature) Austria, 06 August 2018
Oncology
Key words: Cbl-b deficiency, UVB, skin damage, inflammation, gene signature [more]
Organism: Mouse, Human
Tissue: Skin
Expression and modulation of S100A4 protein by human mast cells
Cellular Immunology (Elsevier) Italy, 04 August 2018
Immunology
Key words: Immunofluorescence Tryptase Metalloproteinase Mast cells biology siRNA [more]
Organism: Human
Tissue: Skin
Pathological State: Bladder Cyst, Crohn's Disease, Cancer
Degeneration of white matter and gray matter revealed by diffusion tensor imaging and pathological mechanism after spinal cord injury in canine
CNS Neuroscience and Therapeutics (Wiley) China, 03 August 2018
Neuroscience
Key words: canine model, diffusion tensor imaging, gray matter, pathological degeneration, spinal cord injury, white matter [more]
Organism: Dog
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Crumpled Aluminum Hydroxide Nanostructures as a Microenvironment Dysregulation Agent for Cancer Treatment
Nano Letters (ACS Publications) Russia, Israel, Slovenia, 02 August 2018
Nanomedicine
Key words: aluminum hydroxide, cancer treatment, Crumpled nanosheets, ion balance, molecular dynamics simulation, tumor microenvironment [more]
Organism: Mouse
Tissue: Allograft Tumor
Pathological State: Cancer
Plk1 overexpression suppresses tumor development by inducing chromosomal instability
Nature Communications (Nature) Spain, Germany, UK, 01 August 2018
Oncology
Key words: Cancer, Cell biology [more]
Organism: Mouse
Tissue: Breast
Pathological State: Cancer
SCID/NOD mice model for 5-FU induced intestinal mucositis: Safety and effects of probiotics as therapy
Pediatrics and Neonatology (Elsevier) Taiwan, 26 July 2018
Gastroenterology
Key words: SCID, cytokines, fluorouracil, mucositis, probiotics [more]
Organism: Mouse
Tissue: Small Intestine
Pathological State: Diarrhea
Trehalose to cryopreserve human pluripotent stem cells
Stem Cell Research (Elsevier) Italy, 25 July 2018
Stem Cell Research
Key words: Cryopreservation, Trehalose, Pluripotent stem cells [more]
Organism: Human
Cell Line: hESCs, lt-NES, hiPSCs
Depletion of Sirt3 leads to the impairment of adipogenic differentiation and insulin resistance via interfering mitochondrial function of adipose-derived human mesenchymal stem cells
Free Radical Research (Taylor and Francis) Taiwan, 23 July 2018
Stem Cell Research
Key words: Adipogenesis, antioxidant defence, human mesenchymal stem cells, insulin resistance, mitochondrial bioenergetics, Sirt3 [more]
Organism: Human
Cell Line: adiposederived human mesenchymal stem cells
Succinate Accumulation Is Associated with a Shift of Mitochondrial Respiratory Control and HIF-1α Upregulation in PTEN Negative Prostate Cancer Cells
International Journal of Molecular Sciences (MDPI) Austria, 21 July 2018
Oncology
Key words: Na+-dicarboxylate transporter, acidic tumor microenvironment, mitochondria, oxidative phosphorylation, prostate cancer, succinate [more]
Organism: Human
Pathological State: Cancer
Cell Line: LNCaP, PC-3 (prostate cancer cell lines)
Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion
Autophagy (Taylor and Francis) The Netherlands, 20 July 2018
Cell Biology
Key words: Autophagy, Golgi, bafilomycin A1, degradative compartments, fusion, lysosomal degradation, lysosomal inhibitors [more]
Organism: Human
Pathological State: Cancer
Cell Line: U2OS (Osteosarcoma cell line), HeLa cells
Prognostic and predictive values of immune infiltrate in patients with head and neck squamous cell carcinoma
Human Pathology (Elsevier) China, 20 July 2018
Oncology
Key words: Head and Neck Squamous Cell Carcinoma, Immunoscore, Prognosis and Predictive, Tumor Infiltrating Lymphocytes [more]
Organism: Human
Tissue: Head and Neck
Pathological State: Cancer
Significant therapeutic effects of adult human multipotent neural cells on spinal cord injury
Stem Cell Research (Elsevier) South Korea, 19 July 2018
Stem Cell Research
Key words: Spinal cord injuries, Adult stem cells, Neural stem cells, Microvasculature, Chemokine1 [more]
Organism: Rat
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Trop-2 plasticity is controlled by epithelial-to-mesenchymal transition
Carcinogenesis (Oxford University Press) Czech Republic, 16 July 2018
Oncology
Key words: phenotype, cancer, carcinoma, epithelium, heterogeneity, antigens, cell lines, membrane glycoproteins, breast, neoplasms, prostate, transcription factor, prostate cancer, carcinogenesis, e-cadherin, tumor progression, epithelial to mesenchymal transition, molecular targeted therapy, tumor cells, malignant [more]
Organism: Human
Tissue: Prostate, Breast
Pathological State: Cancer
Enhancement of chondrogenesis of adipose-derived stem cells in HA-PNIPAAm-CL hydrogel for cartilage regeneration in rabbits
Scientific Reports (Nature) Taiwan, 12 July 2018
Regenerative Medicine
Key words: Biomaterials, Regeneration, hydrogel, cartilage [more]
Organism: Rabbit
Cell Line: rADSCs (rabbit adipose-derived stem cells )
Synergistic Cross‐Talk of Hedgehog and Interleukin‐6 Signaling Drives Growth of Basal Cell Carcinoma
International Journal of Cancer (Wiley) Austria, 10 July 2018
Oncology
Key words: GLI signaling, GLI transcription factors, STAT transcription factors, basal cell carcinoma, hedgehog, interleukin-6 signaling [more]
Organism: Mouse
Tissue: Allograft Tumor
Pathological State: Cancer
Expression of serine peptidase inhibitor Kunitz type 1 in differentiated thyroid cancer
Histochemistry and Cell Biology (Springer) Taiwan, 10 July 2018
Oncology
Key words: Serine protease inhibitor, Hepatocyte growth factor, Thyroid cancer Invasion [more]
Organism: Human
Tissue: Thyroid
Pathological State: Cancer
TERT Promoter Mutations in Solitary Fibrous Tumor
HistoPathology (Wiley) USA, 09 July 2018
Oncology
Key words: ATRX, DAXX, metastasis, outcome, prognosis, risk assessment, solitary fibrous tumour, telomerase reverse transcriptase [more]
Organism: Human
Pathological State: Cancer
Development of a Novel Orthogonal Double Gradient for High‐Throughput Screening of Mesenchymal Stem Cells–Materials Interaction
Advanced Materials Interfaces (Wiley) The Netherlands, 04 July 2018
Biological Materials
Key words: high‐throughput screening, orthogonal double gradient, stem cell, stiffness, wettability [more]
Organism: Human
Cell Line: Mesenchymal stem cells from human bone marrow (hBM-MSCs)
Benzyl isothiocyanate inhibits human brain glioblastoma multiforme GBM 8401 cell xenograft tumor in nude mice in vivo
Environmental Toxicology (Wiley) Taiwan, 04 July 2018
Oncology
Key words: benzyl isothiocyanate, human brain glioblastoma multiforme GBM 8401 cell, in vivo, nude mice, xenograft tumor [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Antrodia cinnamomea produces anti-angiogenic effects by inhibiting the VEGFR2 signaling pathway
Journal of Ethnopharmacology (Elsevier) Taiwan, 28 June 2018
Cell Biology
Key words: Antrodia cinnamomea, Anti-angiogenic activity, Endothelial cells, VEGFR2, STAT3 [more]
Organism: Mouse
Tissue: Lung
Pathological State: Cancer
Dynamics of tissue ingrowth in SIKVAV-modified highly superporous PHEMA scaffolds with oriented pores after bridging a spinal cord transection
Journal of Materials Science: Materials in Medicine (Springer) Czech Republic, 25 June 2018
Regenerative Medicine
Key words: tissue ingrowth, SIKVAV, superporous, PHEMA scaffolds, oriented pores, spinal cord injury, mesenchymal stem cells (MSCs) [more]
Organism: Rat
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Neuroplastic change of cytoskeleton in inferior colliculus after auditory deafferentation
Hearing Research (Elsevier) South Korea, 23 June 2018
Neuroscience
Key words: Auditory deafferentation, Deafness, SMI-32, Neurofilament heavy chain, Inferior colliculus [more]
Organism: Rat
Tissue: Brain
Pathological State: Deafness
Androgen excess in pancreatic β cells and neurons predisposes female mice to type 2 diabetes
The Journal of Clinical Investigation (American Society for Clinical Investigation) USA, 21 June 2018
Oncology
Key words: Beta cells, Diabetes, Endocrinology, Metabolism, Sex hormones [more]
Organism: Mouse
Tissue: Pancreas
Pathological State: Diabetes
Afatinib restrains K-RAS–driven lung tumorigenesis
Science Translational Medicine (American Association for the Advancement of Science) Austria, 20 June 2018
Oncology
Key words: Afatinib, K-RAS, lung cancer, pan-ERBB, tyrosine kinase inhibitors [more]
Organism: Mouse
Tissue: Lung
Pathological State: Cancer
Competition between TIAM1 and Membranes Balances Endophilin A3 Activity in Cancer Metastasis
Developmental Cell (Cell Press) USA, 18 June 2018
Oncology
Key words: BAR domain, PTEN, Rac1, TIAM1, cell migration, endocytosis, endophilin, membrane remodeling, metastasis [more]
Organism: Mouse
Tissue: Whole Organism
Pathological State: Cancer
Endothelial colony forming cells from human umbilical cord blood improved severe erectile dysfunction in obese type II diabetic rats
Life Science (Elsevier) Singapore, 18 June 2018
Reproductive Medicine
Key words: Severe erectile dysfunction, Human endothelial colony forming cells, Intracavernosal pressure, Zucker diabetic fatty rats [more]
Organism: Rat
Tissue: Penis
Pathological State: Erectile dysfunction
Quantitative measurement of breast carcinoma fibrosis for the prediction in the risk of bone metastasis
American Journal of Translational Research (e-Century Publishing Corporation) China, 15 June 2018
Oncology
Key words: Invasive breast carcinoma, bone metastasis, collagen deposition, early prediction [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles
EMBO Journal (EMBO press) The Netherlands, 15 June 2018
Oncology
Key words: Cre‐LoxP, extracellular vesicles, intratumoral heterogeneity, intravital microscopy, signaling networks [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Substance P modulates bone remodeling properties of murine osteoblasts and osteoclasts
Scientific Reports (Nature) Germany, 15 June 2018
Physiology
Key words: Substance P, bone remodeling, osteoblasts, osteoclasts, Bone, Mechanisms of disease [more]
Organism: Mouse
Cell Line: Osteoclast, Osteoblast
Synergistic Antitumor Effect of Oligogalacturonides and Cisplatin on Human Lung Cancer A549 Cells
International Journal of Molecular Sciences (MDPI) Taiwan, 14 June 2018
Oncology
Key words: adjuvant therapy, cisplatin, oligogalacturonides, synergistic effect [more]
Organism: Human
Pathological State: Cancer
Cell Line: A549 (Lung carcinoma cells)
Nerve Growth Factor (NGF)—Receptor Survival Axis in Head and Neck Squamous Cell Carcinoma
International Journal of Molecular Sciences (MDPI) Austria, 14 June 2018
Oncology
Key words: TissueFaxs, cell cycle arrest, cytokeratin, necrosis [more]
Organism: Human
Tissue: Mucosa
Pathological State: Cancer
Breast Cancer Histological Image Classification Using Fine-Tuned Deep Network Fusion
International Conference Image Analysis and Recognition (Springer) , 06 June 2018
Key words: Breast cancer Histological images Classification Deep learning
Targeted intracerebral delivery of the anti-inflammatory cytokine IL13 promotes alternative activation of both microglia and macrophages after stroke
Journal of Neuroinflammation (Springer) Germany, 04 June 2018
Immunology
Key words: Interleukin 13, Mesenchymal stem cells, Microglia/macrophage polarization, Neuroinflammation, Stroke [more]
Organism: Mouse
Tissue: Brain
Pathological State: Cerebral Ischemia
Novel Conducting and Biodegradable Copolymers with Noncytotoxic Properties toward Embryonic Stem Cells
ACS OMEGA (ACS Publications) Brazil, 31 May 2018
Stem Cell Research
Key words: Cell and Molecular biology, Conducting polymers, Environmental biology, Polyesters [more]
Organism: Human
Cell Line: Human embryonic stem cells (hESCs)