Customer Publications (A total of 1715 papers published)

Next-Generation Digital Histopathology of the Tumor Microenvironment

F Mungenast, A Fernando, R Nica, B Boghiu, B Lungu, J Batra, RC Ecker

Genes (MDPI) Austria, Australia, Romania, 07 April 2021

Medical Image Analysis

Key words: next-generation digital histopathology, tissue cytometry, multiplexing, RNA ISH, cancer, tumor immune microenvironment, tumor microenvironment

Therapeutic effect of modulating the NLRP3-regulated transforming growth factor-β signaling pathway on interstitial cystitis/bladder pain syndrome

HJ Shih, CY Chang, CH Lai, CJ Huang

Biomedicine & Pharmacotherapy (Elsevier) Taiwan, 01 April 2021

Pharmacology

Key words: Inflammation, Bladder, Inflammasome, Curcumin, Fibrosis [more]

Human skin aging is associated with increased expression of the histone variant H2A. J in the epidermis

CE Rübe, C Bäumert, N Schuler, A Isermann, Z Schmal, M Glanemann, C Mann, H Scherthan

npj Aging and Mechanisms of Disease (Nature) Germany, France, 01 April 2021

Aging

Key words: Aging, Epigenetics [more]

Characterization of innate and adaptive immune cells involved in the foreign body reaction to polypropylene meshes in the human abdomen

A Dievernich, P Achenbach, L Davies, U Klinge

Hernia (Springer) Germany, UK, 31 March 2021

Immunology, Tissue Engineering

Key words: Foreign body reaction, Adaptive immune system, Innate immune system, Mesh, Fluorescence microscopy [more]

n-Butyl Benzyl Phthalate Exposure Promotes Lesion Survival in a Murine Endometriosis Model

P Sharma, JYL Lee, EM Tsai, Y Chang, JJ Suen

International Journal of Environmental Research and Public Health (MDPI) Taiwan, 31 March 2021

Reproductive Medicine

Key words: n-Butyl benzyl phthalate, CD44, dendritic cell, endometriosis [more]

Therapeutic Effect of Cinnamomum osmophloeum Leaf Extract on Oral Mucositis Model Rats Induced by 5-Fluororacil via Influencing IL-1β and IL-6 Levels

A Bakar, V Ningrum, SC Lee, CT Li, CW Hsieh, SH Wang, MS Tsai

Processes (MDPI) Indonesia, Taiwan, 31 March 2021

Pharmacology

Key words: Cinnamomum osmophloeum, Oral mucositis, model rat, 5-Fluororacil, IL-1β, IL-6 [more]

Hypoxia and oxidative stress induce sterile placental inflammation in vitro

BC Baker, AEP Heazell, C Sibley, R Wright, H Bischof, F Beards, T Guevara, S Girard, RL Jones

Scientific Reports (Nature) UK, Canada, 31 March 2021

Reproductive Medicine

Key words: Developmental biology, Diseases, Immunology, Medical research, Pathogenesis [more]

Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells

M Delacher, M Simon, L Sanderink, A Hotz-Wagenblatt, M Wuttke, K Schambeck, L Schmidleithner, S Bittner, A Pant, U Ritter, T Hehlgans, D Riegel, V Schneider, FK Groeber-Becker, A Eigenberger, C Gebhard, N Strieder, A Fischer, M Rehli, P Hoffmann, M Edinger, T Strowig, J Huehn, C Schmidl, JM Werner, L Prantl, B Brors, CD Imbusch, M Feuerer

Immunity (Elsevier) Germany, 30 March 2021

Immunology

[more]

Maternal Angiotensin Increases Placental Leptin in Early Gestation via an Alternative Renin-Angiotensin System Pathway: Suggesting a Link to Preeclampsia

O Nonn, C Fischer, S Geisberger, A El-Heliebi, T Kroneis, D Forstner, G Desoye, AC Staff, M Sugulle, R Dechend, U Pecks, M Kollmann, C Stern, JE Cartwright, GS Whitley, B Thilaganathn, C Wadsack, B Huppertz, F Herse, M Gauster

Hypertension (American Heart Association) Austria, Germany, Norway, UK, 29 March 2021

Reproductive Medicine

Key words: candesartan, leptin, oxygen, respiration, trophoblasts [more]

Expression of CD9 on porcine lymphocytes and its relation to T cell differentiation and cytokine production

JV Milburn, A Hoog, S Winkler, KA van Dongen, J Leitner, M Patzl, A Saalmüller, K de Luca, P Steinberger, KH Mair, W Gerner

Developmental & Comparative Immunology (Elsevier) Austria, France, 27 March 2021

Immunology

Key words: Tetraspanin, CD9, Porcine, Lymphocyte, Memory [more]

Selective Denervation of the Facial Dermato-Muscular Complex in the Rat: Experimental Model and Anatomical Basis

V Tereshenko, DC Dotzauer, U Maierhofer, C Festin, M Luft, G Laengle, O Politikou, HJ Klein, R Blumer, OC Aszmann, KD Bergmeister

Frontiers in Neuroanatomy (Frontiers Media S.A.) Austria, Switzerland, 22 March 2021

Neuroscience

Key words: facial nerve, trigeminal nerve, motor-sensory control, facial muscles, axon quantification, whole-mount staining [more]

Peroxisome-driven ether-linked phospholipids biosynthesis is essential for ferroptosis

W Cui, D Liu, W Gu, B Chu

Cell Death & Differentiation (Nature) China, USA, 17 March 2021

Oncology

Key words: Cancer metabolism, Phospholipids [more]

Luteolin Modulates the NF-E2-Related Factor 2/Glutamate–Cysteine Ligase Pathway in Rats with Spinal Cord Injury

J Fu, W Xu, Y Zhang, H Sun, J Zhao

Journal of Medicinal Food (Mary Ann Liebert Inc.) China, 16 March 2021

Neuroscience

Key words: luteolin, Nrf2/GCL pathway, oxidative stress, spinal cord injury [more]

Machine perfused donor kidneys as a source of human renal endothelial cells

RGM Lammerts, LM Lagendijk, G Tiller, WA Dam, HL Lancaster, MR Daha, MA Seelen, BG Hepkema, RA Pol, HGD Leuvenink, G Molema, J van den Born, SP Berger, the COMBAT Consortium

American Journal of Physiology (American Physiological Society) The Netherlands, 15 March 2021

Nephrology

Key words: Kidney, transplantation, endothelial cells, machine perfusion, perfusate [more]

Genetic Drivers of Head and Neck Squamous Cell Carcinoma: Aberrant Splicing Events, Mutational Burden, HPV Infection and Future Targets

Z Dlamini, M Alaouna, S Mbatha, A Bhayat, M Mabongo, A Chatziioannou, R Hull

Genes (MDPI) South Africa, Greece, 15 March 2021

Oncology

Key words: head and neck squamous cell carcinoma (HNSCC), aberrant splicing events, human papillomavirus (HPV) infection, non-coding RNA (ncRNA), methylation, mutational burden

A Novel ALDH2 Activator AD-9308 Improves Diastolic and Systolic Myocardial Functions in Streptozotocin-Induced Diabetic Mice

HL Lee, SW Hee, CF Hsuan, W Yang, JY Huang, YL Lin, CN Hsu, JJ Hwang, SM Chen, ZZ Ding, TY Lee, YC Lin, FC Tsai, WL Su, LY Chueh, ML Hsieh, CH Chen, D Mochly-Rosen, YC Chang, LM Chuang

Antioxidants (MDPI) Taiwan, USA, 13 March 2021

Cardiology, Endocrinology

Key words: diabetic cardiomyopathy, 4-hydroxy-2-nonenal, mitochondrial aldehyde dehydrogenase 2, AD-9308 [more]

MicroRNA-126 inhibits pathological retinal neovascularization via suppressing vascular endothelial growth factor expression in a rat model of retinopathy of prematurity

YY Fan, CH Liu, AL Wu, HC Chen, YJ Hsueh, KJ Chen, CC Lai, CY Huang, WC Wu

European Journal of Pharmacology (Elsevier) Taiwan, 13 March 2021

Pharmacology

Key words: miR-126, retinal pigment epithelium cells, vascular endothelial growth factor, oxygen-induced retinopathy, neovascularization, rat [more]

N-Acetyl Cysteine Overdose Inducing Hepatic Steatosis and Systemic Inflammation in Both Propacetamol-Induced Hepatotoxic and Normal Mice

GG Liou, CC Hsieh, YJ Lee, PH Li, MS Tsai, CT Li, SH Wang

Antioxidants (MDPI) Taiwan, 12 March 2021

Hepathology

Key words: acetaminophen overdose, N-acetyl cysteine overdose, two inbred mouse strains, hepatic inflammation, systemic inflammation, microvesicular steatosis [more]

Dissecting pathways to thrombocytopenia in a mouse model of visceral leishmaniasis

GF Rani, O Preham, H Ashwin, N Brown, IS Hitchcock, PM Kaye

Blood Advances (ASH Publications) UK, 12 March 2021

Immunology

Key words: blood platelets, infections, leishmania donovani, leishmaniasis, visceral, mice, thrombocytopenia, drug clearance, thrombopoietin, spleen, liver [more]

CHPF Regulates the Aggressive Phenotypes of Hepatocellular Carcinoma Cells via the Modulation of the Decorin and TGF-β Pathways

CH Liu, BR Wu, YJ Ho, YH Chu, WC Hsu, TJ Tseng, JP Li, WC Liao

Cancers (MDPI) Taiwan, 12 March 2021

Oncology

Key words: hepatocellular carcinoma, tumor microenvironment, chondroitin polymerizing factor, chondroitin sulfate, decorin [more]

KLF4, Slug and EMT in Head and Neck Squamous Cell Carcinoma

J Ingruber, D Savic, TB Steinbichler, S Sprung, F Fleischer, R Glueckert, G Schweigl, II Skvortsova, H Riechelmann, J Dudás

Cells (MDPI) Austria, 12 March 2021

Oncology

Key words: TissueFaxs, TWIST, ZEB, SCC-25, FaDu, UPCI-SCC090 [more]

Dietary Modification Alters the Intrarenal Immunologic Micromilieu and Susceptibility to Ischemic Acute Kidney Injury

J Jeon, K Lee, KE Yang, JE Lee, GY Kwon, W Huh, DJ Kim, YG Kim, HR Jang

Frontiers in Immunology (Frontiers Media S.A.) South Korea, 11 March 2021

Immunology, Nephrology

Key words: diet, high-salt diet, high-fat diet, acute kidney injury, immunologic micromilieu, ischemia-reperfusion injury [more]

Genome-wide 5-hydroxymethylcytosine Profiling Analysis Identifies MAP7D1 as A Novel Regulator of Lymph Node Metastasis in Breast Cancer

SL Wu, X Zhang, M Chang, C Huang, J Qian, Q Li, F Yuan, L Sun, X Yu, X Cui, J Jiang, M Cui, Y Liu, HW Wu, ZYLiang, X Wang, Y Niu, WM Tong, F jin

Genomics, Proteomics & Bioinformatics (Elsevier) China, 11 March 2021

Proteomics, Oncology

Key words: 5-Hydroxymethylcytosine (5hmC), Breast cancer, Lymph node metastasis, MAP7D1, Biomarker [more]

A first-in-human phase 0 clinical study of RNA interference–based spherical nucleic acids in patients with recurrent glioblastoma

P Kumthekar, CH Ko, T Paunesku, K Dixit, AM Sonabend, O Bloch, M Tate, M Schwartz, L Zuckerman, R Lezon, RV Lukas, B Jovanovic, K McCortney, H Colman, S Chen, B Lai, O Antipova, J Deng, L Li, S Tommasini-Ghelfi, LA Hurley, D Unruh, NV Sharma, M Kandpal, FM Kouri, RV Davuluri, DJ Brat, M Muzzio, M Glass, V Vijayakumar, J Heidel, FJ Giles, AK Adams, CD James, GE Woloschak, C Horbinski, AH Stegh

Science Translational Medicine (AAAS) USA, 10 March 2021

Oncology

[more]

CHPF promotes malignancy of breast cancer cells by modifying syndecan-4 and the tumor microenvironment

WC Liao, HR Yen, CH Chen, YH Chu, YC Song, TJ Tseng, CH Liu

American Journal of Cancer Research (e-Century Publishing Corporation) Taiwan, 01 March 2021

Oncology

Key words: Breast cancer, chondroitin sulfate, CHPF, tumor microenvironment, syndecan-4 [more]

Akebia saponin D ameliorates metabolic syndrome (MetS) via remodeling gut microbiota and attenuating intestinal barrier injury

S Yang, T Hu, H Liu, Y Lv, W Zhang, H Li, L Xuan, LL Gong, LH Liu

Biomedicine & Pharmacotherapy (Elsevier) China, USA, 27 February 2021

Gastroenterology

[more]

Parathyroid hormone induces transition of myofibroblasts in arteriovenous fistula and increases maturation failure

CT Liu, SC Hsu, HL Hsieh, CH Chen, CY Chen, YM Sue, FY Lin, CM Shih, YT Shiu, PH Huang

Endocrinology, Cardiology (Oxford Academic) Taiwan, USA, 26 February 2021

Endocrinology

Key words: Arteriovenous fistula (AVF), Fibrosis, Hemodialysis, Parathyroid hormone (PTH) [more]

Gastric Enzyme Supplementation Inhibits Food Allergy in a BALB/c Mouse Model

N Samadi, D Heiden, M Klems, M Salzmann, J Rohrhofer, E Weidmann, L Koidl, E Jensen-Jarolim, E Untersmayr

Nutrients (MDPI) Austria, 26 February 2021

Allergy Research

Key words: food allergy, gastric enzymes, gastric acid suppression, systemic allergic response, allergy prevention [more]

Genetic Background Effects on the Expression of an Odorant Receptor Gene

AG Leme Silva, MH Nagai, TS Nakahara, B Malnic

Frontiers in cellular Neuroscience (Frontiers Media S.A.) Brazil, 25 February 2021

Neuroscience

Key words: DNA methylation, odorant receptor gene, olfactory receptor gene, genetic background, gene expression, single nucleotide polymorphism [more]

Regulation of pancreatic fibrosis by acinar cell-derived exosomal miR-130a-3p via targeting of stellate cell PPAR-γ

Q Wang, H Wang, Q Jing, Y Yang, D Xue, C Hao, W Zhang

Journal of Inflammation Research (Dovepress) China, 24 February 2021

Gastroenterology

Key words: pancreatitis, exosomes, miR-130a-3p, pancreatic fibrosis, PPAR-γ [more]

Accuracy of HPV E6/E7 mRNA examination using in situ hybridization in diagnosing cervical intraepithelial lesions

C Hui, H Bai, J Liu, X Lu, S Wang, Z Zhang, M Jin, Y Wang, Y Liu

Diagnostic Pathology (Springer) China, 19 February 2021

Pathology

Key words: Cervical intraepithelial neoplasia, CIN, Diagnostic accuracy, E6/E7 mRNA, In situ hybridization [more]

T cell-tropic HIV efficiently infects alveolar macrophages through contact with infected CD4+ T cells

Abigail E. Schiff, Alice H. Linder, Shillah N. Luhembo, Stephanie Banning, Martin J. Deymier, Thomas J. Diefenbach, Amy K. Dickey, Athe M. Tsibris, Alejandro B. Balazs, Josalyn L. Cho, Benjamin D. Medoff, Gerhard Walzl, Robert J. Wilkinson, Wendy A. Burgers, Björn Corleis, Douglas S. Kwon

Scientific reports (Nature) USA, South Africa, UK, Germany, 16 February 2021

Virology

Key words: HIV infections, Monocytes and macrophages, Mucosal immunology, Retrovirus, Virology, Virus–host interactions [more]

Imbalance of TGF-β1/BMP-7 pathways induced by M2-polarized macrophages promotes hepatocellular carcinoma aggressiveness

J Ning, Y Ye, D Bu, G Zhao, T Song, P Liu, W Yu, H Wang, H Li, X Ren, G Ying, Y Zhao, J Yu

Molecular Therapy (Elsevier) China, 15 February 2021

Oncology

[more]

Curcumin inhibits the growth of liver cancer by impairing myeloid‑derived suppressor cells in murine tumor tissues

S Tian, L Liao, Q Zhou, X Huang, P Zheng, Y Guo, T Deng, X Tian

Oncology Letters (Spandidos Publications) China, 12 February 2021

Oncology

[more]

Insulin gene enhancer protein 1 mediates glycolysis and tumorigenesis of gastric cancer through regulating glucose transporter 4

T Guo, YH Bai, XJ Cheng, HB Han, H Du, Y Hu, SQ Jia, XF Xing, JF Ji

Cancer Communications (Wiley) China, 11 February 2021

Oncology

Key words: gastric cancer, glucose transporter 4, glycolysis, insulin gene enhancer protein 1, tumorigenesis [more]

Global Analysis of Lysine Acetylome Reveals the potential role of CCL18 in non‐small cell lung cancer

S Kong, L Ding, C Fan, Y Li, C Wang, K Wang, W Xu, X Shi, Q Wu, F Wang

Proteomics (Wiley) China, 11 February 2021

Proteomics

Key words: acetylome, CCL18, non-small cell lung cancer [more]

Histone citrullination as a novel biomarker and target to inhibit progression of abdominal aortic aneurysms

Wolf Eilenberg, Branislav Zagrapan, Sonja Bleichert, Nahla Ibrahim, Viktoria Knöbl, Annika Brandau, Luca Martelanz, Marie-Therese Grasl, Hubert Hayden, Paimann Nawrozi, Renata Rajic, Charlotte Häusler, Alexandros Potolidis, Nawa Schirwani, Andreas Scheuba, Johannes Klopf, Peter Teubenbacher, Markus P Weigl, Patrick Kirchweger, Dietrich Beitzke, Alexander Stiglbauer-Tscholakoff, Adelheid Panzenböck, Irene Lang, Lisa-Marie Mauracher, Lena Hell, Ingrid Pabinger, Marc A Bailey, D Julian A Scott, Lars Maegdefessel, Albert Busch, Ihor Huk, Christoph Neumayer, Christine Brostjan

Translational Research (Elsevier) Austria, UK, Sweden, 09 February 2021

Cardiology

[more]

IgG4 induces tolerogenic M2-like macrophages and correlates with disease progression in colon cancer

G Jordakieva, R Bianchini, D Reichhold, J Piehslinger, A Groschopf, SA Jensen, E Mearini, G Nocentini, R Crevenna, GJ Zlabinger, SN Karagiannis, A Klaus, E Jensen-Jarolim

OncoImmunology (Taylor & Francis) Austria, Italy, UK, 08 February 2021

Oncology

Key words: IgG4, IgE, tumor-associated macrophages, M2b, allergooncology [more]

Anti-inflammatory effects of Radix aucklandiae herbal preparation ameliorate intestinal mucositis induced by 5-fluorouracil in mice

JH Liu, CH Hsieh, CY Liu, CW Chang, YJ Chen, TH Tsai

Journal of Ethnopharmacology (Elsevier) Taiwan, 07 February 2021

Pharmacology

Key words: 5-Fluorouracil (5-FU), Radix aucklandiae, Intestinal mucositis, Goblet cell, Anti-inflammatory [more]

Hiltonol Cocktail Kills Lung Cancer Cells by Activating Cancer-Suppressors, PKR/OAS, and Restraining the Tumor Microenvironment

SC Chang, BX Zhang, ECY Su, WC Wu, TH Hsieh, AM Salazar, YK Lin, JL Ding

International Journal of Molecular Sciences (MDPI) Taiwan, USA, Singapore, 05 February 2021

Oncology

Key words: NSCLC (non-small cell lung cancer), combinatorial treatment with Hiltonol+++ cocktail [Hiltonol+anti-IL6+stattic+AG490], tumorigenic microenvironment, anti- and pro-tumorigenic cytokine production, tumor-suppressors PKR (protein kinase R) and OAS (2′5′ oligoadenylate synthetase) [more]

H2S-mediated aerobic exercise antagonizes the hippocampal inflammatory response in CUMS-depressed mice.

L Ruilian, Q Honglin, X Jun, L Jianxin, B Qingyun, C Yilin, M Haifeng

Journal of Affective Disorders (Elsevier) China, 05 February 2021

Neuroscience

Key words: Chronic stress stimulated depression model, Hippocampus, Hydrogen sulfide, Inflammatory, Aerobic exercise [more]

Morphine acts on spinal dynorphin neurons to cause itch through disinhibition

E Nguyen, G Lim, H Ding, J Hachisuka, MC Ko, SE Ross

Science Translational Medicine (AAAS) USA, UK, 03 February 2021

Neuroscience

[more]

Irreversible electroporation ablation overcomes tumor-associated immunosuppression to improve the efficacy of DC vaccination in a mice model of pancreatic cancer

J Yang, A Eresen, J Shangguan, Q Ma, V Yaghmai, Z Zhang

OncoImmunology (Taylor & Francis) USA, 02 February 2021

Oncology

Key words: Irreversible electroporation, dendritic cell vaccine, pancreatic ductal adenocarcinoma, magnetic resonance imaging [more]

Expression of chondroitin sulfate proteoglycan 4 (CSPG4) in melanoma cells is downregulated upon inhibition of BRAF

K Uranowska, T Kalic, V Valtsanidis, M Kitzwögerer, H Breiteneder, C Hafner

Oncology Reports (Spandidos Publications) Austria, 02 February 2021

Oncology

[more]

iTRAQ-based Quantitative Proteomic Analysis of Dural Tissues Reveals Upregulated Haptoglobin to be a Potential Biomarker of Moyamoya Disease

X Zhang, L Yin, X Jia, Y Zhang, T Liu, L Zhang

Current Proteomics (ingentaconnect) China, 01 February 2021

Proteomics

Key words: Moyamoya disease, dura mater, proteomics, iTRAQ, haptoglobin, strokes

Nerve Fibers in the Tumor Microenvironment Are Co-Localized with Lymphoid Aggregates in Pancreatic Cancer

LR Heij, X Tan, JN Kather, JM Niehues, S Sivakumar, N Heussen, G van der Kroft, SWM Olde Damink, S Lang, MR Aberle, T Luedde, NT Gaisa, J Bednarsch, DHW Liu, JPM Cleutjens, DP Modest, UP Neuman, GJ Wiltberger

Journal of Clinical Medicine (MDPI) Germany, The Netherlands, UK, Austria, 30 January 2021

Oncology

Key words: tumor microenvironment, machine learning, nerve fiber density, spatial arrangements, tertiary lymphoid structures, pancreatic cancer [more]

Endothelial-Derived miR-17∼ 92 Promotes Angiogenesis to Protect against Renal Ischemia-Reperfusion Injury

T Chiba, DM Cerqueira, Y Li, AJ Bodnar, E Mukherjee, K Pfister, YL Phua, K Shaikh, BT Sanders, SL Hemker, PJ Pagano, YL Wu, J Ho, S Sims-Lucas

Journal of the American Society of Nephrology (Am Soc Nephrol) USA, 29 January 2021

Nephrology

Key words: microRNA, acute kidney injury, renal microvasculature

Mer tyrosine kinase (MerTK) as a possible link between resolution of inflammation and tissue fibrosis in IgG4-related disease

L Rovati, N Kaneko, F Pedica, A Monno, T Maehara, C Perugino, M Lanzillotta, S Pecetta, JH Stone, C Doglioni, AA Manfredi, S Pillai, E Della-Torre

Rheumatology (Oxford Academic) Italy, USA, Japan, 29 January 2021

Rheumatology

Key words: IgG4-related disease, macrophages, MerTK, Protein S, fibrosis [more]

Effects of Nicorandil on Inflammation, Apoptosis and Atherosclerotic Plaque Progression

M Lenz, C Kaun, KA Krychtiuk, P Haider, M Brekalo, N Maier, L Goederle, CJ Binder, K Huber, C Hengstenberg, J Wojta, PJ Hohensinner, WS Speidl

Biomedicines (MDPI) Austria, 27 January 2021

Cardiology

Key words: nicorandil, inflammation, apoptosis, atherosclerosis, plaque, plaque stabilization [more]

Interleukin-24 protects against liver injury in mouse models

HH Wang, JH Huang, MH Sue, WC Ho, YH Hsu, KC Chang, MS Chang

EBioMedicine (THE LANCET) Taiwan, 25 January 2021

Hepathology

Key words: Interleukin-24, Liver fibrosis, Thioacetamide-induced liver injury, Hepatic stellate cells [more]

Immune Modulation Effects of Lactobacillus casei Variety rhamnosus on Enterocytes and Intestinal Stem Cells in a 5-FU-Induced Mucositis Mouse Model

CY Yeung, JSC Chiau, ML Cheng, WT Chan, SW Chang, CB Jiang, HC Lee

Gastroenterology Research and Practice (Hindawi Publishing Corporation) Taiwan, 25 January 2021

Gastroenterology

[more]

A Hepatitis B Virus-Derived Peptide Exerts an Anticancer Effect via TNF/iNOS-producing Dendritic Cells in Tumor-Bearing Mouse Model

SB Yang, MH Lee, BR Kim, YM Choi, BJ Kim

Cancers (MDPI) South Korea, 22 January 2021

Oncology

Key words: HBV-derived poly6 peptide, TNF/iNOS-producing DCs (Tip-DCs), type 1 interferon (IFN-I), CD40, cancer immunotherapy [more]

Androgen Plays a Carcinogenic Role in EOC via the PI3K/AKT Signaling Pathway in an AR-Dependent Manner

Y Li, S Li, Y Zhang, S Shi, S Qin, C Wang, J Du, J Ma, H Chen, H Cui

Journal of Cancer (Ivyspring International Publisher) China, 21 January 2021

Oncology

Key words: ovarian carcinoma, androgen receptor (AR), tissue microarray (TMA), proliferation promotion, PI3K/AKT signalling pathway [more]

Performance and Meat Quality of Intrauterine Growth Restricted Pigs

P Matyba, T Florowski, K Dasiewicz, K Ferenc, J Olszewski, M Trela, G Galemba, M Słowiński, M Sady, D Domańska, Z Gajewski, R Zabielski

Animals (MDPI) Poland, 20 January 2021

Zoology

Key words: IUGR, pigs, growth performance, meat quality, sensory evaluation [more]

Pathological Pulmonary Vascular Remodeling is Induced by Type V Collagen in a Model of Scleroderma

RG Marangoni, BD Korman, ER Parra, APP Velosa, HV Barbeiro, V Martins, ABG dos Santos, F Soriano, WR Teodoro, PL Silva, W Tourtellotte, VL Capelozzi, J Varga, NH Yoshinari

Pathology - Research and Practice (Elsevier) Brazil, USA, 19 January 2021

Cardiology

Key words: Animal model, scleroderma, Collagen V, Vascular disease, Endothelium [more]

Comparison of two fluorescent probes in preclinical non-invasive imaging and image-guided debridement surgery of Staphylococcal biofilm implant infections

HY Park, SD Zoller, V Hegde, W Sheppard, Z Burke, G Blumstein, C Hamad, M Sprague, J Hoang, R Smith, FR Pastrana, J Czupryna, LS Miller, M López-Álvarez, M Bispo, M van Oosten, J Maarten van Dijl, KP Francis, NM Bernthal

Scientific reports (Nature) USA, The Netherlands, 15 January 2021

Medical Imaging

Key words: Biofilms, Infectious diseases

PEG-GO@ XN nanocomposite suppresses breast cancer metastasis via inhibition of mitochondrial oxidative phosphorylation and blockade of epithelial-to …

J Zhang, L Yan, P Wei, R Zhou, C Hua, M Xiao, Y Tu, Z Gu, T Wei

European Journal of Pharmacology (Elsevier) China, USA, 14 January 2021

Oncology, Nanomedicine

Key words: Graphene oxide, Xanthohumol, Breast cancer metastasis, Mitochondria, Epithelial-mesenchymal transition, Energy metabolism [more]

Macromolecular crowding as a tool to screen anti-fibrotic drugs: the Scar-in-a-Jar system revisited

NP Cavanzo, E Bigaeva, M Boersema, P Olinga, RA Bank

Frontiers in Medicine (Frontiers Media S.A.) The Netherlands, China, USA, Switzerland, 14 January 2021

Biological Methods

Key words: macromolecular crowding, drug testing, fibrosis, collagen, myofibroblast [more]

Mesenchymal stem cell‐glioblastoma interactions mediated via kinin receptors unveiled by cytometry

MM Pillat, Á Oliveira‐Giacomelli, M das Neves Oliveira, R Andrejew, N Turrini, J Baranova, TL Turnšek, H Ulrich

Cytometry Part A (Wiley) Brazil, 13 January 2021

Medical Image Analysis

Key words: cytometry, glioblastoma, kinin receptors, kinin‐B1 receptor, kinin‐B2 receptor, mesenchymal stem cells [more]

Overexpression of neuregulin 1 in GABAergic interneurons results in reversible cortical disinhibition

YY Wang, B Zhao, MM Wu, XL Zheng, L Lin, DM Yin

Nature communications (Nature) China, 12 January 2021

Neuroscience

Key words: Molecular neuroscience, Schizophrenia [more]

Stem Cell-Derived Respiratory Epithelial Cell Cultures as Human Disease Models

JC Orr, RE Hynds

American Journal of Respiratory Cell and Molecular Biology (Wiley) UK, 11 January 2021

Stem Cell Research

Key words: respiratory epithelium, epithelial cells, cell culture, cloning, stem cells

Overexpression of GLUT3 promotes metastasis of triple‐negative breast cancer by modulating the inflammatory tumor microenvironment

TH Tsai, CC Yang, TC Kou, CE Yang, JZ Dai, CL Chen, CW Lin

Journal of Cellular Physiology (Wiley) Taiwan, 09 January 2021

Oncology

Key words: glycolysis, inflammation, triple‐negative breast cancer, tumor microenvironment, tumor‐associated macrophage [more]

Development and Validation of Sorafenib-eluting Microspheres to Enhance Therapeutic Efficacy of Transcatheter Arterial Chemoembolization in a Rat Model of of Hepatocellular Carcinoma

W Park, S Cho, J Ji, RJ Lewandowski, AC Larson, DH Kim

Radiology: Imaging Cancer (Royal Society of Chemistry) USA, 08 January 2021

Oncology

[more]

Differential expression of microRNA miR-150-5p in IgA nephropathy as a potential mediator and marker of disease progression.

IZA Pawluczyk, A Didangelos, SJ Barbour, L Er, JU Becker, R Martin, S Taylor, JS Bhachu, EG Lyons, R Jenkins, D Fraser, K Molyneux, J Perales-Paton, J Saez-Rodriguez, J Barratt

Kidney International (Elsevier) UK, Canada, Germany, Spain, 06 January 2021

Nephrology

Key words: IgA nephropathy, microRNA [more]

Hypoxia-induced suppression of alternative splicing of MBD2 promotes breast cancer metastasis via activation of FZD1

Z Liu, L Sun, Y Cai, S Shen, T Zhang, N Wang, G Wu, W Ma, ST Li, C Suo, Y Hao, WD Jia, GL Semenza, P Gao, H Zhang

Cancer Research (AACR) China, USA, 05 January 2021

Oncology

Stressed erythrophagocytosis induces immunosuppression during sepsis through heme-mediated STAT1 dysregulation

Tolani F. Olonisakin, Tomeka Suber, Shekina Gonzalez-Ferrer, Zeyu Xiong, Hernán F. Peñaloza, Rick van der Geest, Yuting Xiong, David O. Osei-Hwedieh, Jesús Tejero, Matthew R. Rosengart, Wendy M. Mars, Daria Van Tyne, Andreas Perlegas, Samuel Brashears, Daniel B. Kim-Shapiro, Mark T. Gladwin, Michael A. Bachman, Eldad A. Hod, Claudette St. Croix, Yulia Y. Tyurina, Valerian E. Kagan, Rama K. Mallampalli, Anuradha Ray, Prabir Ray, Janet S. Lee

The Journal of Clinical Investigation (American Society of Clinical Investigation) USA, 04 January 2021

Immunology

[more]

IN VITRO CHARACTERIZATION OF HYDROXYAPATITE-BASED BIOMATERIALS, USING MESENCHYMAL STEM CELL CULTURES FROM HUMAN BONE …

LE Sima, RM Varut, O Gingu, G Sima, C Teisanu, J Neamtu

Journal of Science and Arts (Josa.ro) Romania, 30 December 2020

Biological Materials

Key words: hydroxyapatite, calcium fructoborate, mesenchymal stem cell, human bone marrow [more]

Persistent inhibition of Candida albicans biofilm and hyphae growth on titanium by graphene nanocoating

SV Agarwalla, K Ellepola, N Silikas, AHC Neto, C Jayampath, SV Rosa

Dental Materials (Elsevier) Singapore, USA, UK, 25 December 2020

Biological Materials

Key words: Implant, Surface free energy, Contact angle, Topography, Microbial attachment, Antiadhesive coating, Peri-Implantitis [more]

Obesity is associated with shorter telomere length in prostate stromal cells in men with aggressive prostate cancer

CE Joshu, CM Heaphy, JR Barber, J Lu, R Zarinshenas, C Davis, M Han, TL Lotan, KS Sfanos, AM De Marzo, AK Meeker, EA Platz

Cancer Prevention Research (AACR) USA, 22 December 2020

Oncology

PD‐L1+ dendritic cells in the tumor microenvironment correlate with good prognosis and CD8+ T cell infiltration in colon cancer

TJ Miller, CC Anyaegbu, TF Lee‐Pullen, LJ Spalding, CF Platell, MJ McCoy

Cancer Science (Wiley) Australia, 20 December 2020

Oncology

Key words: CD8, colon cancer, Dendritic cells, PD‐L1, T cells

Heterogeneous Tumor-Immune Microenvironments between Primary and Metastatic Tumors in a Patient with ALK Rearrangement-Positive Large Cell Neuroendocrine Carcinoma

T Tashiro, K Imamura, Y Tomita, D Tamanoi, A Takaki, K Sugahara, R Sato, K Saruwatari, S Sakata, M Inaba, S Ushijima, N Hirata, T Sakagami

International Journal of Molecular Sciences (MDPI) Japan, USA, 19 December 2020

Oncology

Key words: anaplastic lymphoma kinase (ALK), B cell, heterogeneity, immune checkpoint, large cell neuroendocrine carcinoma (LCNEC), neuroendocrine tumors (NET), regulatory T-cells (Tregs), programmed death-ligand 1 (PD-L1), tumor-infiltrating lymphocyte (TIL), tumor-immune microenvironments (TIME) [more]

Parp1-Dependent DNA Double-Strand Break Repair in Irradiated Late Pachytene Spermatocytes

E A. Ahmed, A M. Alzahrani, H Scherthan

DNA and Cell Biology (Mary Ann Liebert Inc.) Saudi Arabia, Egypt, Germany, 18 December 2020

Reproductive Medicine

Key words: alternative NHEJ, DNA repair, first meiotic prophase, γ-H2AX, homologous recombination, Parp1, spermatogenesis [more]

Differential mast cell phenotypes in benign versus cancer tissues and prostate cancer oncologic outcomes

H Hempel Sullivan, JP Maynard, CM Heaphy, J Lu, AM De Marzo, TL Lotan, CE Joshu, KS Sfanos

The Journal of Pathology (Wiley) USA, 18 December 2020

Oncology

Key words: Prostate cancer, mast cells, metastases, CXCR4, TFE3, KIT, microenvironment [more]

ZFHX3 Knockdown Dysregulates Mitochondrial Adaptations to Tachypacing in Atrial Myocytes through Enhanced Oxidative Stress and Calcium Overload

B Lkhagva, YK Lin, YC Chen, WL Cheng, S Higa, YH

Acta Physiologica (Wiley) Taiwan, Japan, 17 December 2020

Physiology

Key words: atrial fibrillation, calcium, mitochondria, tachypacing, ZFHX3 [more]

CD4+ CTLs in Fibrosing Mediastinitis Linked to Histoplasma capsulatum

H Allard-Chamard, F Alsufyani, N Kaneko, K Xing, C Perugino, VS Mahajan, JL Wheat, GS Deepe Jr., J Loyd and S Pillai

The Journal of Immunology (American Association of Immunologists) Canada, Saudi Arabia, Japan, USA, 16 December 2020

Immunology

[more]

Tribbles Pseudokinase 3 Contributes to Cancer Stemness of Endometrial Cancer Cells by Regulating β-Catenin Expression

WL Wang, GC Hong, PJ Chien, YH Huang, HT Lee, PH Wang, YC Lee, WW Chang

Cancers (MDPI) Taiwan, 15 December 2020

Oncology

Key words: tribbles pseudokinase 3, endometrial cancer, cancer stem cells, β-catenin, epithelial–mesenchymal transition [more]

Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer's Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals

TJ Hark, NR Rao, C Castillon, T Basta, S Smukowski, H Bao, A Upadhyay, E Bomba-Warczak, T Nomura, ET O'Toole, GP Morgan, L Ali, T Saito, C Guillermier, TC Saido, ML Steinhauser, MHB Stowell, ER Chapman, A Contractor, JN Savas

Cell Systems (Cell Press) USA, Japan, 15 December 2020

Neuroscience

Key words: Alzheimer's diseasea, myloid beta, synaptic dysfunction, presynapse, synaptic vesicles, proteostasis, mass spectrometry, proteomics, APP knockin mice [more]

Multi-Cohort Retrospective Validation of a Predictive Biomarker for Topoisomerase I Inhibitors

K Ando, A Ozonoff, SY Lee, M Viosine, JT Parker, R Nakanishi, S Nishimura, J Yang, Z Grace, B Tran, TJ Diefenbach, Y Maehara, H Yasui, T Irino, R Salgia, M Terashima, P Gibbs, RK Ramanathan, E Oki, M Mori, M Kulke, K Hartshorn, A Bharti

Clinical Colorectal Cancer (Elsevier) USA, Japan, Australia, 10 December 2020

Oncology

[more]

Spatiotemporal Up-Regulation of Mu Opioid Receptor 1 in Striatum of Mouse Model of Huntington's Disease Differentially Affecting Caudal and Striosomal Regions

R Morigaki, JH Lee, T Yoshida, C Wüthrich, D Hu, JR Crittenden, A Friedman, Y Kubota, AM Graybiel

Frontiers in Neuroanatomy (Frontiers Media S.A.) USA, Japan, 10 December 2020

Neuroscience

Key words: mu opioid receptors, Huntington’s disease, neostriatum, movement disorders, mood disorders, animal models of human disorders, striosome [more]

Bioinstructive Micro-Nanotextured Zirconia Ceramic Interfaces for Guiding and Stimulating an Osteogenic Response In Vitro

L Elena Sima, A Bonciu, M Baciu, I Anghel, LN Dumitrescu, L Rusen, V Dinca

Nanomaterials (MDPI) Romania, 09 December 2020

Nanomedicine

Key words: Zirconia, mesenchymal stem cells, micro-nano topography, osteogenic differentiation, bone-anchored hearing aid (BAHA) [more]

The effect of dietary supplementation with high-or low-dose omega-3 fatty acid on inflammatory pathology after traumatic brain injury in rats

EK Black, JK Phillips, J Seminetta, J Bailes, JM Lee, JD Finan

Translational Neuroscience (degruyter) USA, 09 December 2020

Neuroscience

Key words: dietary supplementation, docosahexanoic acid, eicosapentaenoic acid, neuroinflammation, neuroprotection, omega-3 fatty acid, traumatic brain injury [more]

Hypomethylation of PlncRNA-1 promoter enhances bladder cancer progression through the miR-136-5p/Smad3 axis

W Kang, Q Wang, Y Dai, H Wang, M Wang, J Wang, D Zhang, P Sun, T Qi, X Jin, Z Cui

Cell Death & Disease (Nature) China, 07 December 2020

Oncology

Key words: Bladder cancer, Long non-coding RNAs, Oncogenesis [more]

Integrative single-cell transcriptome analysis reveals a subpopulation of fibroblasts associated with favorable prognosis of liver cancer patients

H Wang, C Feng, M Lu, B Zhang, Y Xu, Q Zeng, J Xi, J Zhou, X Ying, J Zhang, W Yue, X Pei

Translational Oncology (Elsevier) China, 06 December 2020

Oncology

Key words: Liver cancer, Single-cell transcriptome, Cancer-distinct fibroblast, SPARCL1 [more]

Lactic acidosis interferes with toxicity of perifosine to colorectal cancer spheroids: multimodal imaging analysis

B Pavlatovská, M Machálková, P Brisudová, A Pruška, K Štěpka, J Michálek, T Nečasová, P Beneš, J Šmarda, J Preisler, M Kozubek, J Navrátilová

Frontiers in Oncology (Frontiers Media S.A.) Czech Republic, Switzerland, China, 04 December 2020

Oncology

Key words: perifosine, Akt kinase, tumor environment, lactic acidosis, alkalization, signal co-registration, mass spectrometry imaging, colorectal cancer [more]

AC Pulsed Field Ablation Is Feasible and Safe in Atrial and Ventricular Settings: A Proof-of-Concept Chronic Animal Study

G Caluori, E Odehnalova, T Jadczyk, M Pesl, I Pavlova, L Valikova, S Holzinger, V Novotna, V Rotrekl, A Hampl, M Crha, D Cervinka, Z Starek

Frontiers in Bioengineering and Biotechnology (Frontiers Media S.A.) Czech Republic, France, Poland, Germany, 03 December 2020

Cardiology

Key words: pulsed field ablation, irreversible electroporation (IRE), radiofrequency ablation, atrial fibrillation, ventricular arrhythmia (VA), preclinical cardiology [more]

Shear stress-exposed pulmonary artery endothelial cells fail to upregulate HSP70 in chronic thromboembolic pulmonary hypertension

W Salibe-Filho, TLS Araujo, EG Melo, LBCT Coimbra, MS Lapa, MMP Acencio, O Freitas-Filho, VL Capelozzi, LR Teixeira, CJCS Fernandes, F Biscegli Jatene, FRM Laurindo, M Terra-Filho

PloS one (PLOS) Brazil, 03 December 2020

Cardiology

Key words: Shear stresses, Endothelial cells, Heat shock response, Pulmonary arteries, Peas, Flow cytometry, Nitric oxide, Pulmonary hypertension [more]

Infiltration of metastatic lymph nodes with PD-1+ T cells is associated with improved disease-free and overall survival in resected N+ NSCLC

S Wang, Y Song, MA Morse, P Sun, G Qiao, X Wang, X Zhou, A Hobeika, J Ren, HK Lyerly

American Journal of Cancer Research (e-Century Publishing Corporation) China, USA, 01 December 2020

Oncology

Key words: NSCLC, metastatic lymph node, T cell subsets, PD-1, TIM-3 [more]

The predictive power of CD3+ T cell infiltration of oral squamous cell tumors is limited to non-diabetic patients

G Spanier, I Ugele, F Nieberle, L Symeou, S Schmidhofer, A Brand, J Meier, S Spoerl, R Krupar, P Rümmele, P Siska, K Renner, K Peter, M Gerken, P Beckhove, TE Reichert, M Kreutz, K Singer

Cancer Letters (Elsevier) Germany, 01 December 2020

Oncology

Key words: OSCC, Diabetes mellitus, TIL, Metabolism, Prognosis [more]

p21‐activated kinase 4 promotes the progression of esophageal squamous cell carcinoma by targeting LASP1

H Huang, Q Xue, X Du, J Cui, J Wang, D Cheng, J Li, Y Zheng, G Huang, K Zhang, K Liu, J Lu, J Zhao, X Chen, Z Dong, X Li

Molecular Carcinogenesis (Wiley) China, 01 December 2020

Oncology

Key words: cell proliferation, esophageal squamous cell carcinoma, LASP1, metastasis, PAK4 [more]

Cross-Reactive Effects of Vaccines: Heterologous Immunity between Tetanus and Chlamydia

M Stojanovic, I Lukic, E Marinkovic, A Kovacevic, R Miljkovic, J Tobias, I Schabussova, M Zlatovic, T Barisani-Asenbauer, U Wiedermann, A Inic-Kanada

Vaccines (MDPI) Serbia, Austria, 01 December 2020

Immunology

Key words: vaccination, heterologous immunity, antibodies, tetanus, Chlamydia, cross-reactivity [more]

Levodopa Improves Cognitive Function and the Deficits of Structural Synaptic Plasticity in Hippocampus Induced by Global Cerebral Ischemia/Reperfusion Injury in Rats

W Wang, X Liu, Z Yang, H Shen, L Liu, Y Yu, T Zhang

Frontiers in Neuroscience (Frontiers Media S.A.) China, 30 November 2020

Neuroscience

Key words: levodopa, hippocampus, global cerebral ischemia reperfusion injury, structural synaptic plasticity, cognitive function [more]

Characterization of epithelial cells, connective tissue cells and immune cells in human upper airway mucosa by immunofluorescence multichannel image cytometry: a pilot study

AI Giotakis, J Dudas, R Glueckert, D Dejaco, J Ingruber, F Fleischer, V innerhofer, L Pinggera, L Bektic-Tadic, SAM Gabriel, H Riechelmann

Histochemistry and Cell Biology (Springer) Austria, 29 November 2020

Medical Image Analysis

Key words: Image cytometry, Fluorescent antibody technique, Immunohistochemistry, Nasal mucosa, Sinusitis [more]

MicroRNA-146a suppresses tumor malignancy via targeting vimentin in esophageal squamous cell carcinoma cells with lower fibronectin membrane assembly

HY Chang, CH Lee, YS Li, JT Huang, SH Lan, YF Wang, WW Lai, YC Wang, YJ Lin, HS Liu, HC Cheng

Journal of Biomedical Science (BMC) Taiwan, 28 November 2020

Oncology

Key words: ESCC, miR-146a, Vimentin, Cell migration, Invasion [more]

Lactobacillus Attenuate the Progression of Pancreatic Cancer Promoted by Porphyromonas Gingivalis in K-rasG12D Transgenic Mice

SM Chen, LJ Hsu, HL Lee, CP Lin, SW Huang, CJL Lai, CW Lin, WT Chen, YJ Chen, YC Lin, CC Yang, MS Jan

Cancers (MDPI) Taiwan, 26 November 2020

Oncology

Key words: caerulein, Lactobacillus, pancreatic ductal adenocarcinoma, Porphyromonas Gingivalis, transforming growth factor-β [more]

Visfatin Enhances Breast Cancer Progression through CXCL1 Induction in Tumor-Associated Macrophages

YY Wang, HD Chen, S Lo, YK Chen, YC Huang, S CS Hu, YC Hsieh, AC Hung, MF Hou, SS F Yuan

Cancers (MDPI) Taiwan, UK, 26 November 2020

Oncology

Key words: visfatin, breast cancer, tumor-associated macrophages, CXCL1 [more]

Nrf2 knockout altered brain iron deposition and mitigated age-related motor dysfunction in aging mice

K Han, X Jin, X Guo, G Cao, S Tian, Y Song, Y Zuo, P Yu, G Gao, YZ Chang

Free Radical Biology and Medicine (Elsevier) China, 26 November 2020

Neuroscience

Key words: Nrf2, Motor dysfunction, Brain iron metabolism, Oxidative stress, FPN1 [more]

Neuropathology changed by 3-and 6-months low-level PM 2.5 inhalation exposure in spontaneously hypertensive rats

HC Chuang, HC Chen, PJ Chai, HT Liao, CF Wu, CL Chen, MK Jhan, HI Hsieh, KY Wu, TF Chen, TJ Cheng

Particle and Fibre Toxicology (Springer) Taiwan, 26 November 2020

Neuroscience

Key words: Air pollution, Autophagy, Central nervous system toxicity, Particulate matter, Tau [more]

Electric Pulse Responsive Magnetic Nanoclusters Loaded with Indoleamine 2, 3-Dioxygenase Inhibitor for Synergistic Immuno-Ablation Cancer Therapy

B Yu, W Zhang, K Kwak, H Choi, DH Kim

ACS Applied Materials & Interfaces (ACS Publications) USA, 25 November 2020

Oncology

Key words: local ablation, irreversible electroporation, indoleamine 2, 3-dioxygenase inhibitor, magnetic nanoparticles, immunotherapy [more]

Development of Rift valley fever encephalitis in rats is mediated by early infection of olfactory epithelium and neuroinvasion across the cribriform plate

DA Boyles, MM Schwarz, JR Albe, CM Mcmillen, KJ O'Malley, DS Reed, AL Hartman

Journal of General Virology (Microbiology Society) USA, 24 November 2020

Virology

Key words: aerosol, cribriform plate, encephalitis, olfactory bulb, pathogenesis, Rift Valley fever virus [more]

Time-resolved analysis of Staphylococcus aureus invading the endothelial barrier

EJM Raineri, H Yedavally, A Salvati, JM van Dijl

Virulence (Taylor & Francis) The Netherlands, 22 November 2020

Microbiology

Key words: Staphylococcus aureus, MRSA, endothelium, invasion, intracellular [more]

Type II natural killer T cells contribute to protection against systemic methicillin-resistant Staphylococcus aureus infection

S Genardi, L Visvabharathy, L Cao, E Morgun, Y Cui, C Qi, YH Chen, L Gapin, E Berdyshev, CR Wang

Frontiers in Immunology (Frontiers Media S.A.) USA, 18 November 2020

Immunology

Key words: Staphylococcus aureus, natural killer T cells, CD1, lipid antigens, cytokine, knockout mice [more]

Long-term skin-resident memory T cells proliferate in situ and are involved in human graft-versus-host disease

J Strobl, RV Pandey, T Krausgruber, N Bayer, L Kleissl, B Reininger, P Vieyra-Garcia, P Wolf, MM Jentus, M Mitterbauer, W Rabitsch, G Stingl, C Bock, G Stray

Science Translational Medicine (AAAS) Austria, 18 November 2020

Dermatology

[more]

Correlation Between Early Plasma Interleukin 37 Responses With Low Inflammatory Cytokine Levels and Benign Clinical Outcomes in Severe Acute Respiratory Syndrome Coronavirus 2 Infection

Ang Li, Yun Ling, Zhigang Song, Xiaobo Cheng, Longfei Ding, Rendi Jiang, Weihui Fu, Yan Liu, Huiliang Hu, Songhua Yuan, Jian Chen, Cuisong Zhu, Jun Fan, Jing Wang, Yanling Jin, Miaomiao Zhang, Lingyan Zhu, Peng Sun, Linxia Zhang, Ran Qin, Wei Zhang, Chenli Qiu, Yinzhong Shen, Lin Zhang, Zhengli Shi, Chen Zhao, Tongyu Zhu, Hongzhou Lu, Xiaoyan Zhang, Jianqing Xu

The Journal of Infectious Diseases (Oxford Academic) China, 17 November 2020

Covid-19

Key words: IL-37, SARS-CoV-2, COVID-19, inflammation, clinical outcomes [more]

Deviant reporter expression and P2X4 passenger gene overexpression in the soluble EGFP BAC transgenic P2X7 reporter mouse model

A Ramírez-Fernández, L Urbina-Treviño, G Conte, M Alves, B Rissiek, A Durner, N Scalbert, J Zhang, T Magnus, F Koch-Nolte, N Plesnila, JM Deussing, T Engel, R Kopp, A Nicke

Scientific Reports (Nature) Germany, Ireland, 16 November 2020

Neuroscience

Key words: Biological techniques, Molecular biology, Neuroscience [more]

HCN channels in the mammalian cochlea: Expression pattern, subcellular location, and age‐dependent changes

M Luque, A Schrott‐Fischer, J Dudas, E Pechriggl, E Brenner, H Rask-Andersen, W Liu, R Glueckert

Journal of Neuroscience Research (Wiley) Austria, 12 November 2020

Neuroscience

Key words: auditory development, auditory neuron diversity, axon initial segment, HCN channels, prestin, RRID:AB_90725, RRID:AB_2039906, RRID:AB_2302038, RRID:AB_2313584, RRID:AB_2313726, RRID:AB_2336419, RRID:AB_2336420, RRID:AB_2336790, RRID:AB_2340477, RRID:AB_2340452, RRID:AB_2340593, RRID:AB_2341028, RRID:AB_2617143, RRID:AB_2756625, RRID:AB_2756742, RRID:SCR_002865, RRID:SCR_013652, RRID:SCR_014823, sound coding, spiral ganglion neurons, voltage gated [more]

Inhibition of aquaporin-3 in macrophages by a monoclonal antibody as potential therapy for liver injury

M Hara-Chikuma, M Tanaka, AS Verkman, M Yasui

Nature communications (Nature) Japan, USA, 09 November 2020

Hepathology

Key words: Molecular Drug discovery, Liver diseases, Molecular medicine [more]

CO2-Responsive Water-Soluble Conjugated Polymers for In Vitro and In Vivo Biological Imaging

CC Cheng, YC Lai, YT Shieh, YH Chang, AW Lee, JK Chen, DJ Lee, JY Lai

Biomacromolecules (ACS Publications) Taiwan, 06 November 2020

Medical Imaging

[more]

Mucus production stimulated by IFN-AhR signaling triggers hypoxia of COVID-19

Y Liu, J Lv, J Liu, M Li, J Xie, Q Lv, W Deng, N Zhou, Y Zhou, J Song, P Wang, C Qin, WM Tong, B Huang

Cell Research (Nature) China, 06 November 2020

Immunology, Covid-19

Key words: Immunology, Innate immunity [more]

Evidence for a non-stochastic two-field hypothesis for persistent skin cancer risk

RL Konger, L Ren, RP Sahu, E Derr-Yellin, YL Kim

Scientific reports (Nature) USA, 05 November 2020

Oncology

Key words: Cancer microenvironment, Cancer models, Skin cancer, Squamous cell carcinoma [more]

Human placental cell line HTR-8/SVneo accumulates cadmium by divalent metal transporters DMT1 and ZIP14

R Widhalm, I Ellinger, S Granitzer, M Forsthuber, R Bajtela, K Gelles, PY Hartig, M Hengstschläger, H Zeisler, H Salzer, C Gundacker

Metallomics (Royal Society of Chemistry) Austria, 04 November 2020

Reproductive Medicine

[more]

Metformin chlorination byproducts in drinking water exhibit marked toxicities of a potential health concern

R Zhang, Y He, L Yao, J Chen, S Zhu, X Rao, P Tang, J You, G Hua, L Zhang, F Ju, L Wu

Environment International (Elsevier) China, 03 November 2020

Toxicology

Key words: Metformin, Metformin chlorination byproduct, Drinking water, Toxicity, Public health [more]

Effect of route of administration on the efficacy of dendritic cell vaccine in PDAC mice

J Yang, A Eresen, J Shangguan, Q Ma, Z Zhang, V Yaghmai

American Journal of Cancer Research (e-Century Publishing Corporation) USA, 01 November 2020

Oncology

Key words: Pancreatic cancer, dendritic cell, route of administration [more]

Therapeutic Efficacy of GC1118, a Novel Anti-EGFR Antibody, against Glioblastoma with High EGFR Amplification in Patient-Derived Xenografts

K Lee, H Koo, Y Kim, D Kim, E Son, H Yang, Y Lim, M Hur, H Won Lee, S Won Choi, DH Nam

Cancers (MDPI) South Korea, 31 October 2020

Oncology

Key words: glioblastoma, epidermal growth factor receptor, monoclonal, xenograft, amplification [more]

P2Y2 receptor activation promotes esophageal cancer cells proliferation via ERK1/2 pathway

A Zaparte, AR Cappellari, CA Brandão, JB de Souza, TJ Borges, LW Kist, MR Bogo, LF Zerbini, LF Ribeiro Pinto, T Glaser, MCB Goncalves, Y Naaldijk, H Ulrich, FB Morrone

European Journal of Pharmacology (Elsevier) Brazil, USA, South Africa, 31 October 2020

Oncology

Key words: Esophageal cancer, Purinergic system, Nucleotide, P2Y2R, Proliferation, Signaling pathways [more]

Calenduloside E suppresses calcium overload by promoting the interaction between L-type calcium channels and Bcl2-associated athanogene 3 to alleviate myocardial ischemia–reperfusion injury

R Wang, M Wang, J Zhou, Z Dai, G Sun, X Sun

Journal of Advanced Research (Elsevier) China, 31 October 2020

Cardiology

Key words: Calenduloside E, myocardial ischemia-reperfusion injury, L-type calcium channelscalcium overload, Bcl2-associated athanogene 3 [more]

B Cell Activating Factor (BAFF) Is Required for the Development of Intra-Renal Tertiary Lymphoid Organs in Experimental Kidney Transplantation in Rats

L Steines, H Poth, M Herrmann, A Schuster, B Banas, T Bergler

International Journal of Molecular Sciences (MDPI) Germany, 28 October 2020

Nephrology

Key words: tertiary lymphoid organs, kidney transplantation, B cells, BAFF [more]

Proteomics of regenerated tissue in response to a titanium implant with a bioactive surface in a rat tibial defect model

RM Boteanu, VI Suica, L Ivan, F Safciuc, E Uyy, E Dragan, SM Croitoru, V Grumezescu, M Chiritoiu, LE Sima, C Vlagioiu, G Socol, F Antohe

Scientific reports (Nature) Romania, 28 October 2020

Osteology

Key words: Bioinformatics, Biological models, Fracture repair, Immunological techniques, Mass spectrometry, Microscopy, Proteomic analysis [more]

Characterization of Negative Allosteric Modulators of the Calcium-Sensing Receptor for Repurposing as a Treatment of Asthma

Polina L. Yarova, Ping Huang, Martin W. Schepelmann, Richard Bruce, Rupert Ecker, Robert Nica, Vsevolod Telezhkin, Daniela Traini, Larissa Gomes dos Reis, Emma J. Kidd, William R. Ford, Kenneth J. Broadley, Benson M. Kariuki, Christopher J. Corrigan, Jeremy P.T. Ward, Paul J. Kemp and Daniela Riccardi

The Journal of Pharmacology and Experimental Therapeutics (ASPET) UK, Austria, Australia, 28 October 2020

Pharmacology

[more]

Striosomes Mediate Value-Based Learning Vulnerable in Age and a Huntington's Disease Model

A Friedman, E Hueske, SM Drammis, SET Arana, ED Nelson, CW Carter, S Delcasso, RX Rodriguez, H Lutwak, KS DiMarco, Q Zhang, LI Rakocevic, D Hu, JK Xiong, J Zhao, LG Gibb, T Yoshida, CA Siciliano, TJ Diefenbach, C Ramakrishnan, K Deisseroth, AM Graybiel

Cell (Cell Press) USA, 27 October 2020

Neuroscience

Key words: corticostriatal, approach-avoidance, cost-benefit, decision-making, utility, subjective value, motivation, parvalbumin interneurons, VGluT1, excitation-inhibition balance [more]

The Immune Phenotype of Isolated Lymphoid Structures in Non-Tumorous Colon Mucosa Encrypts the Information on Pathobiology of Metastatic Colorectal Cancer

F Mungenast, A Meshcheryakova, A Beer, M Salzmann, D Tamandl, T Gruenberger, P Pietschmann, O Koperek, P Birner, I Kirsch, H Robins, M Mittlboeck, M Jaritz, M Bergmann, P Zimmermann, D Mechtcheriakova

Cancers (MDPI) Austria, Switzerland, 25 October 2020

Oncology

Key words: lymphoid structures,  colonic mucosa,  metastatic colorectal cancer,  immuno-oncology,  B lymphocytes,  germinal center,  tissue image cytometry,  B-cell clonality,  compendium-wide analysis,  patient stratification strategy [more]

Cross‐section modified and highly elastic sutures reduce tissue incision and show comparable biocompatibility: in‐vitro and in‐vivo evaluation of novel thermoplastic urethane surgical threads

M Helmedag, D Heise, R Eickhoff, KM Kossel, T Gries, S Jockenhoevel, UP Neumann, CD Klink, A Lambertz

Journal of Biomedical Materials Research Part B (Wiley) Germany, 24 October 2020

Tissue Engineering

Key words: animal trials, biocompatibility, elastic sutures, surface modified surgical threads, thermoplastic polyurethane, tissue incision [more]

Direct signaling of TL1A-DR3 on fibroblasts induces intestinal fibrosis in vivo

Noam Jacob, Kotaro Kumagai, Jay P. Abraham, Yosuke Shimodaira, Yuefang Ye, Justin Luu, Anna Y. Blackwood, Sofi L. Castanon, Dalton T. Stamps, Lisa S. Thomas, Rivkah Gonsky, David Q. Shih, Kathrin S. Michelsen & Stephan R. Targan

Scientific reports (Nature) USA, 23 October 2020

Immunology, Gastroenterology

Key words: Cytokines, Gastroenterology, Immunology, Inflammation, Inflammatory bowel disease [more]

Impaired autophagy increases susceptibility to endotoxin-induced chronic pancreatitis

L Xia, Z Xu, X Zhou, F Bergmann, N Grabe, MW Büchler, JP Neoptolemos, T Hackert, G Kroemer, F Fortunato

Cell death & Disease (Nature) Germany, 21 October 2020

Gastroenterology

Key words: Acute pancreatitis, Chronic pancreatitis [more]

Increased Radiation-Associated T-Cell Infiltration in Recurrent IDH-Mutant Glioma

A Makarevic, C Rapp, S Dettling, D Reuss, C Jungk, A Abdollahi, A van Deimling, A Unterberg, C Herold-Mende, R Warta

International Journal of Molecular Sciences (MDPI) Germany, 21 October 2020

Neuroscience

Key words: lower-grade glioma, T-cell infiltration, TissueFAXS, primary tumors, recurrent tumors, radiotherapy [more]

Tissue remodeling macrophages morphologically dominate at the interface of polypropylene surgical meshes in the human abdomen

A Dievernich, P Achenbach, L Davies, U Klinge

Hernia (Springer) Germany, UK, 18 October 2020

Tissue Engineering

Key words: Foreign body reaction, Macrophage, Collagen, Mesh, Fluorescence microscopy [more]

CDK5 Inhibition Abrogates TNBC Stem‐Cell Property and Enhances Anti‐PD‐1 Therapy

Yuncheng Bei, Nan Cheng, Ting Chen, Yuxin Shu, Ye Yang, Nanfei Yang, Xinyu Zhou, Baorui Liu, Jia Wie, Qin Liu, Wei Zheng, Wenlong Zhang, Huifang Su, Wei‐Guo Zhu, Jianguo Ji, Pingping Shen

Advanced Science (Wiley) China, 15 October 2020

Oncology

Key words: cancer stem cells, CD44 variants, CDK5, immune checkpoint blockade, PPARγ phosphorylation, triple‐negative breast cancer, tumor microenvironment [more]

Poly (ADP-ribose) polymerase inhibitor treatment as a novel therapy attenuating renal ischemia-reperfusion injury

HR Jang, K Lee, J Jeon, JR Kim, JE Lee, GY Kwon, YG Kim, DJ Kim, JW Ko, W Huh

Frontiers in Immunology (Frontiers Media S.A.) South Korea, Italy, France, 14 October 2020

Immunology

Key words: Acute kidney injury, Ischemia-reperfusion injury, poly(ADP-ribose) polymerase (PARP) inhibitor, parthanatos, inflammation, translational immunology [more]

Two Polyurethane Adhesives for PVDF Fixation Show Superior Biocompatibility in a Rat Model

D Heise, Y Mirlas, M Helmedag, R Eickhoff, A Kroh, A Lambertz, CD Klink, UP Neumann, U Klinge, R Tolba

Journal of Investigative Surgery (Taylor & Francis) Germany, The Netherlands, 14 October 2020

Tissue Engineering

Key words: Mesh fixation, polyurethane adhesive, incisional hernia [more]

FATS regulates polyamine biosynthesis by promoting ODC degradation in an ERβ-dependent manner in non-small-cell lung cancer

L Qiu, L Hu, H Wang, J Li, X Ruan, B Sun, J Zhi, X Zheng, L Gu, M Gao, P Kong, J Zhang

Cell death & Disease (Nature) China, 09 October 2020

Oncology

Key words: Apoptosis, Macroautophagy [more]

Immune contexture analysis in immuno‐oncology: applications and challenges of multiplex fluorescent immunohistochemistry

R Shakya, TH Nguyen, N Waterhouse, R Khanna

Clinical & Translational Immunology (Wiley) Australia, 07 October 2020

Immunology

Key words: FCS express image cytometry, immune profiling, multiplexed fluorescent immunohistochemistry, quantitative digital pathology, tumor microenvironment, vectra

Prenatal smoke exposure dysregulates lung epithelial cell differentiation in mouse offspring: role for AREG-induced EGFR signaling

K Lkhagvadorj, Z Zeng, J Song, M Reinders-Luinge, W Kooistra, S Song, S Krauss-Etschmann, BN Melgert, J Cao, MN Hylkema

Journal of Physiology-Lung … (American Physiological Society) The Netherlands, Mongolia, Germany, China, 06 October 2020

Pulmonology

Key words: amphiregulin, epithelial cell differentiation, lung organoids, prenatal smoke exposure [more]

Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during clinical latency

Melanie Werner-Klein, Ana Grujovic, Christoph Irlbeck, Milan Obradović, Martin Hoffmann, Huiqin Koerkel-Qu, Xin Lu, Steffi Treitschke, Cäcilia Köstler, Catherine Botteron, Kathrin Weidele, Christian Werno, Bernhard Polzer, Stefan Kirsch, Miodrag Gužvić, Jens Warfsmann, Kamran Honarnejad, Zbigniew Czyz, Giancarlo Feliciello, Isabell Blochberger, Sandra Grunewald, Elisabeth Schneider, Gundula Haunschild, Nina Patwary, Severin Guetter, Sandra Huber, Brigitte Rack, Nadia Harbeck, Stefan Buchholz, Petra Rümmele, Norbert Heine, Stefan Rose-John & Christoph A. Klein

Nature Communications (Nature) Germany, Switzerland, 05 October 2020

Oncology

Key words: Breast cancer, Cancer [more]

Innovations present in the primate interneuron repertoire

Fenna M. Krienen, Melissa Goldman, Qiangge Zhang, Ricardo C. H. del Rosario, Marta Florio, Robert Machold, Arpiar Saunders, Kirsten Levandowski, Heather Zaniewski, Benjamin Schuman, Carolyn Wu, Alyssa Lutservitz, Christopher D. Mullally, Nora Reed, Elizabeth Bien, Laura Bortolin, Marian Fernandez-Otero, Jessica D. Lin, Alec Wysoker, James Nemesh, David Kulp, Monika Burns, Victor Tkachev, Richard Smith, Christopher A. Walsh, Jordane Dimidschstein, Bernardo Rudy, Leslie S. Kean, Sabina Berretta, Gord Fishell, Guoping Feng & Steven A. McCarroll

Nature (Nature) USA, 30 September 2020

Neuroscience

Key words: Evolutionary biology, Genetics of the nervous system, Transcriptomics [more]

Peptide-Based TNF-α-Binding Decoy Therapy Mitigates Lipopolysaccharide-Induced Liver Injury in Mice

CY Chang, HJ Hsu, J Foo, HJ Shih, CJ Huang

Pharmaceuticals (MDPI) Taiwan, 29 September 2020

Hepathology

Key words: TNF-α, necroptosis, pyroptosis, apoptosis, autophagy, mitochondrial injury [more]

Prothymosin α activates type I collagen to develop a fibrotic placenta in gestational diabetes

HT Wu, L Kang, YC Su, HY Ou, FY Chan, BH Su, YS Wang, CL Wu, AL Shiau, P Wu

Clinical Science (Portland Press) Taiwan, UK, 25 September 2020

Endocrinology

Key words: fibrosis, gestational diabetes, placenta, prothymosin α, trophoblast

A Systemic Prime–Intrarectal Pull Strategy Raises Rectum-Resident CD8+ T Cells for Effective Protection in a Murine Model of LM-OVA Infection

Q He, L Jiang, K Cao, L Zhang, X Xie, S Zhang, X Ding, Y He, M Zhang, C Zhao, X Zhang, J Xu

Frontiers in Immunology (Frontiers Media S.A.) China, 24 September 2020

Immunology

Key words: mucosal immune response, rectum TRM, prime–pull vaccination strategy, HIV, Listeria monocytogenes [more]

Discoidin Domain Receptors 1 Inhibition Alleviates Osteoarthritis via Enhancing Autophagy

HC Chou, CH Chen, LY Chou, TL Cheng, L Kang, SC Chuang, YS Lin, ML Ho, YH Wang, SY Lin, CZ Wang

International Journal of Molecular Sciences (MDPI) Taiwan, 23 September 2020

Rheumatology

Key words: discoidin domain receptors 1 (Ddr1), osteoarthritis (OA), autophagy, apoptosis, terminal differentiation [more]

Mechanical stress regulates autophagic flux to affect apoptosis after spinal cord injury

X Zhang, Y Jing, C Qin, C Liu, D Yang, F Gao, M Yang, L Du, J Li

Journal of Cellular and Molecular Medicine (Wiley) China, 17 September 2020

Neuroscience

Key words: apoptosis, autophagic flux, decompression, mechanical stress, mTOR, spinal cord injury [more]

Two common polymorphic variants of OATP4A1 as potential risk factors for colorectal cancer

Veronika Buxhofer‑Ausch, Orsolya Német, Majdah Sheikh, Hajnalka Andrikovics, Angelika Reiner, Christoph Ausch, Diana Mechtcheriakova, Attila Tordai, Andreas Gleiss, Csilla Özvegy‑laczka, Walter Jäger, Theresia Thalhammer

Oncology Letters (Spandidos Publications) Austria, Hungary, 17 September 2020

Oncology

[more]

Placental Alkaline Phosphatase Promotes Zika Virus Replication by Stabilizing Viral Proteins through BIP

J Chen, Z Chen, M Liu, T Qiu, D Feng, C Zhao, S Zhang, X Zhang, J Xu

mBio (American Society for Microbiolgy) China, 15 September 2020

Virology

Key words: BIP, placental alkaline phosphatase, Zika virus, placental trophoblast cells [more]

IL-20 antagonist suppresses PD-L1 expression and prolongs survival in pancreatic cancer models

SW Lu, HC Pan, YH Hsu, KC Chang, LW Wu, WY Chen, MS Chang

Nature Communications (Nature) Taiwan, 14 September 2020

Oncology

Key words: Interleukins, Pancreatic cancer [more]

In vitro function and in situ localization of Multidrug Resistance-associated Protein (MRP) 1 (ABCC1) suggest a protective role against methyl mercury-induced oxidative stress in the human placenta

Sebastian Granitzer, Isabella Ellinger, Rumsha Khan, Katharina Gelles, Raimund Widhalm, Markus Hengstschläger, Harald Zeisler, Gernot Desoye, Lenka Tupova, Martina Ceckova, Hans Salzer, Claudia Gundacker

Archives of Toxicology (Springer) Austria, Czech Republic, 11 September 2020

Toxicology

Key words: Multidrug resistance-associated protein 1, Methyl mercury, HTR-8/Svneo, MDCKII, Oxidative stress, Human placenta [more]

The Metalloproteinase ADAMTS5 Is Expressed by Interstitial Inflammatory Cells in IgA Nephropathy and Is Proteolytically Active on the Kidney Matrix

S Taylor, M Whitfield, J Barratt, A Didangelos

The Journal of Immunology (American Association of Immnologists) UK, 11 September 2020

Immunology

[more]

Iminostilbene, a novel small-molecule modulator of PKM2, suppresses macrophage inflammation in myocardial ischemia-reperfusion injury

S Lu, Y Tian, Y Luo, X Xu, W Ge, G Sun, X Sun

Journal of Advanced Research (Elsevier) China, 09 September 2020

Cardiology

Key words: Myocardial ischemia-reperfusion, Macrophage, Iminostilbene, Pyruvate kinase M2 [more]

Integrin VLA-4 as a PET imaging biomarker of hyper-adhesion in transgenic sickle mice

Lydia A. Perkins, Lea Nyiranshuti, Lynda Little-Ihrig, Joseph D. Latoche, Kathryn E. Day, Qin Zhu, Sina Tavakoli, Prithu Sundd, Enrico M. Novelli, Carolyn J. Anderson

Blood Advances (ASH Publications) USA, 03 September 2020

Cardiology

Key words: adhesions, biological markers, diagnostic imaging, integrins, mice, monoclonal antibodies, positron-emission tomography, selectins, flow cytometry, femur [more]

Progranulin Administration Attenuates β-Amyloid Deposition in the Hippocampus of 5xFAD Mice Through Modulating BACE1 Expression and Microglial Phagocytosis

Z Guan, Z Chen, S Fu, L Dai, Y Shen

Frontiers in Cellular Neuroscience (Frontiers Media S.A.) China, 03 September 2020

Neuroscience

Key words: Alzheimer’s disease, progranulin, Aβ, BACE1, microglia [more]

Assessment of a long-term in vitro model to characterize the mechanical behavior and macrophage-mediated degradation of a novel, degradable, electrospun poly-urethane vascular graft

M Enayati, S Puchhammer, J Iturri, C Grasl, C Kaun, S Baudis, I Walter, H Schima, R Liska, J Wojta, JL Toca-Herrera, BK Podesser, H Bergmeister

Journal of the Mechanical Behavior of Biomedical Materials (Elsevier) Austria, 03 September 2020

Tissue Engineering

Key words: Biodegradation, Mechanical stability, Macrophages, Thermoplastic polyurethane, Cell culture, Rat model [more]

Assessment of a long-term in vitro model to characterize the mechanical behavior and macrophage-mediated degradation of a novel, degradable, electrospun poly-urethane vascular graft

M Enayati, S Puchhammer, J Iturri, C Grasl, C Kaun, S Baudis, I Walter, H Schima, R Liska, J Wojta, JL Toca-Herrera, BK Podesser, H Bergmeister

Journal of the Mechanical Behavior of Biomedical Materials (Elsevier) Austria, 03 September 2020

Biological Materials

Key words: Biodegradation, Mechanical stability, Macrophages, Thermoplastic polyurethane, Cell culture, Rat model

Murine induced pluripotent stem cell‐derived neuroimmune cell culture models emphasize opposite immune‐effector functions of interleukin 13‐primed microglia and macrophages in terms of neuroimmune toxicity

A Quarta, T Meese, Z Pieters, E Van Breedam, D Le Blon, J Van Broeckhoven, S Hendrix, H Goossens, N Hens, Z Berneman, F Van Nieuwerburgh, P Ponsaerts

Glia (Wiley) Belgium, Germany, Spain, The Netherlands, 31 August 2020

Neuroscience

Key words: bioluminescence imaging, interleukin 13, iPSC, macrophages, microglia, neurotoxicity, transcriptome [more]

The Secretome of Stressed Peripheral Blood Mononuclear Cells Increases Tissue Survival in a Rodent Epigastric Flap Model

Stefan Hacker, Rainer Mittermayr, Denise Traxler, Claudia Keibl, Annika Resch, Stefan Salminger, Harald Leiss, Philipp Hacker, Christian Gabriel, Bahar Golabi, Reinhard Pauzenberger, Paul Slezak, Maria Laggner, Michael Mildner, Wolfgang Michlits, Hendrik J. Ankersmit

Bioengineering & Translational Medicine (Wiley) Austria, 30 August 2020

Tissue Engineering

Key words: secretome, angiogenesis, flap surgery, necrosis reconstructive surgery, tissue regeneration [more]

Alum triggers infiltration of human neutrophils ex vivo and causes lysosomal destabilization and mitochondrial membrane potential‐dependent NET‐formation

M Reithofer, J Karacs, J Strobl, C Kitzmüller, D Polak, K Seif, M Kamalov, CFW Becker, G Greiner, K Schmetterer

The FASEB Journal (Wiley) Austria, 29 August 2020

Cardiology

Key words: aluminium hydroxide, vaccine, adjuvant, innate response, neutrophils, NET [more]

Radix Polygalae extract exerts antidepressant effects in behavioral despair mice and chronic restraint stress-induced rats probably by promoting autophagy and inhibiting neuroinflammation

Y Zhou, M Yan, R Pan, Z Wang, X Tao, C Li, T Xia, X Liu, Q Chang

Journal of Ethnopharmacology (Elsevier) China, 28 August 2020

Neuroscience

Key words: Depression, Radix polygalae, Chronic restraint stress, Autophagy, Neuroinflammation [more]

Topography-Mediated Myotube and Endothelial Alignment, Differentiation, and Extracellular Matrix Organization for Skeletal Muscle Engineering

AM Almonacid Suarez, MGL Brinker, LA Brouwer, I van der Ham, MC Harmsen, P van Rijn

Polymers (MDPI) The Netherlands, 28 August 2020

Tissue Engineering

Key words: myoblasts, topography, vascularization, endothelial cells, skeletal muscle, extracellular matrix [more]

Effects of pharmacological calcimimetics on colorectal cancer cells over-expressing the human calcium-sensing receptor

L Iamartino, T Elajnaf, K Gall, J David, T Manhardt, P Heffeter, M Grusch, S Derdak, S Baumgartner-Parzer, M Schepelmann, E Kallay

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (Elsevier) Austria, 27 August 2020

Oncology

Key words: Calcium-sensing receptor, Calcimimetic, Colorectal cancer, Inflammation, Intestine [more]

The Effects of Skin Lesion Segmentation on the Performance of Dermatoscopic Image Classification

A Mahbod, P Tschandl, G Langs, R Ecker, I Ellinger

Computer Methods and Programs in Biomedicine (Elsevier) Austria, 26 August 2020

Medical Image Analysis

Key words: Skin cancer, dermatoscopy, medical image analysis, deep learning, effect of segmentation on classification

Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma

Jason K. Sa, Nakho Chang, Hye Won Lee, Hee Jin Cho, Michele Ceccarelli, Luigi Cerulo, Jinlong Yin, Sung Soo Kim, Francesca P. Caruso, Mijeong Lee, Donggeon Kim, Young Taek Oh, Yeri Lee, Nam-Gu Her, Byeongkwi Min, Hye-Jin Kim, Da Eun Jeong, Hye-Mi Kim, Hyunho Kim, Seok Chung, Hyun Goo Woo, Jeongwu Lee, Doo-Sik Kong, Ho Jun Seol, Jung-Il Lee, Jinho Kim, Woong-Yang Park, Qianghu Wang, Erik P. Sulman, Amy B. Heimberger, Michael Lim, Jong Bae Park, Antonio Iavarone, Roel G. W. Verhaak & Do-Hyun Nam

Genome Biology (BMC) South Korea, Italy, China, USA, 26 August 2020

Oncology

[more]

Hindbrain Double-Negative Feedback Mediates Palatability-Guided Food and Water Consumption

R Gong, S Xu, A Hermundstad, Y Yu, SM Sternson

CELL (Cell Press) USA, 24 August 2020

Neuroscience

Key words: hunger, thirst, palatability, locus coeruleus, locus ceruleus, periLC, ingestive behavior, appetite, in vivo calcium imaging, GRIN lens [more]

Interruption of vascular endothelial growth factor receptor 2 signaling induces a proliferative pulmonary vasculopathy and pulmonary hypertension

Max-Paul Winter, Smriti Sharma, Johanna Altmann, Veronika Seidl, Adelheid Panzenböck, Arman Alimohammadi, Thomas Zelniker, Bassam Redwan, Felix Nagel, David Santer, Alexander Stieglbauer, Bruno Podesser, Maria Sibilia, Thomas Helbich, Gerald Prager, Aysegül Ilhan-Mutlu, Matthias Preusser, Irene M. Lang

Basic Research in Cardiology (Springer) Austria, Germany, 23 August 2020

Pulmonology

Key words: Pulmonary hypertension, VEGFR-2, FLK, Kdr, Murine model [more]

Loss of Bcl-6-expressing T follicular helper cells and germinal centers in COVID-19

Naoki Kaneko, Hsiao-Hsuan Kuo, Julie Boucau, Jocelyn R. Farmer, Hugues Allard-Chamard, Vinay S. Mahajan, Alicja Piechocka-Trocha, Kristina Lefteri, Matthew Osborn, Julia Bals, Yannic C. Bartsch, Nathalie Bonheur, Timothy M. Caradonna, Josh Chevalier, Fatema Chowdhury, Thomas J. Diefenbach, Kevin Einkauf, Jon Fallon, Jared Feldman, Kelsey K. Finn, Pilar Garcia-Broncano, Ciputra Adijaya Hartana, Blake M. Hauser, Chenyang Jiang, Paulina Kaplonek, Marshall Karpell, Eric C. Koscher, Xiaodong Lian, Hang Liu, Jinqing Liu, Ngoc L. Ly, Ashlin R. Michell, Yelizaveta Rassadkina, Kyra Seiger, Libera Sessa, Sally Shin, Nishant Singh, Weiwei Sun, Xiaoming Sun, Hannah J. Ticheli, Michael T. Waring, Alex L.

CELL (Cell Press) USA, Canada, 19 August 2020

Covid-19

Key words: SARS-CoV-2, COVID-19, T follicular helper cells, germinal centers, double-negative B cells, extra-follicular B cells, plasmablasts, humoral immunity, TNF-α, cytokine dysregulation [more]

Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer

R Vatapalli, V Sagar, Y Rodriguez, JC Zhao, K Unno, S Pamarthy, B Lysy, J Anker, H Han, YA Yoo, M Truica, ZR Chalmers, F Giles, J Yu, D Chakravarti, B Carneiro, SA Abdulkadir

Nature Communications (Nature) USA, 19 August 2020

Oncology

Key words: Epigenomics, Prostate cancer, Targeted therapies [more]

Short-course radiotherapy promotes pro-inflammatory macrophages via extracellular vesicles in human rectal cancer

V Stary, B Wolf, D Unterleuthner, J List, M Talic, J Längle, A Beer, J Strobl, G Stary, H Dolznig, M Bergman

Journal for ImmunoTherapy of Cancer (BMJ Journals) Austria, 18 August 2020

Oncology

Key words: macrophages, radiotherapy, tumor microenvironment [more]

Epithelial cell–specific loss of function of Miz1 causes a spontaneous COPD-like phenotype and up-regulates Ace2 expression in mice

HC Do-Umehara, C Chen, Q Zhang, AV Misharin, H Abdala-Valencia, SM Casalino-Matsuda, PA Reyfman, KR Anekalla, FJ Gonzalez-Gonzalez, MA Sala, C Peng, P Wu, CCL Wong, R Kalhan, A Bharat, H Perlman, KM Ridge, JI Sznajder, PHS Sporn, NS Chandel, J Yu, X Fu, I Petrache, R Tuder, GRS Budinger, J Liu

Science Advances (AAAS) USA, China, 14 August 2020

Immunology

[more]

Prenatal smoke exposure dysregulates lung epithelial cell differentiation in mouse offspring-Role for AREG-induced EGFR signaling.

K Lkhagvadorj, Z Zeng, J Song, M Reinders-Luinge, W Kooistra, S Song

American Journal of Physiology (American Physiological Society) The Netherlands, China, 12 August 2020

Pulmonology

Key words: Prenatal smoke exposure, Epithelial cell differentiation, Amphiregulin, Lung organoids [more]

Dysregulated Kras/YY1/ZNF322A/Shh transcriptional axis enhances neo-angiogenesis to promote lung cancer progression

CC Lin, IY Kuo, LT Wu, WH Kuan, SY Liao, J Jen, YE Yang, CW Tang, YR Chen, YC Wang

Theranostics (Ivyspring International Publisher) Taiwan, 08 August 2020

Oncology

Key words: Lung cancer, Kras, Shh, transcription, angiogenesis [more]

The effects of CYP24A1 on clinicopathological features and the prognosis of pancreatic ductal adenocarcinoma

W Gao, TF Wang, W Yi, WM Tong

Translational Cancer Research (AME Publishing Company) China, 08 August 2020

Oncology

Key words: CYP24A1, pancreatic cancer, prognosis [more]

Human FBXL8 Is a Novel E3 Ligase Which Promotes BRCA Metastasis by Stimulating Pro-Tumorigenic Cytokines and Inhibiting Tumor Suppressors

SC Chang, W Hsu, ECY Su, CS Hung, JL Ding

Cancers (MDPI) Taiwan, Singapore, 07 August 2020

Oncology

Key words: FBXL8 SCF E3 ubiquitin ligase, CCND2, IRF5, breast cancer (BRCA) and metastasis, pro-tumorigenic microenvironment [more]

Pyramidal shaped ceria nano-biointerfaces for studying the early bone cell response

AF Bonciu, S Orobeti, LE Sima, M Icriverzi, M Filipescu, A Moldovan, A Popescu, V Dinca, M Dinescu

Applied Surface Science (Elsevier) Romania, 06 August 2020

Biological Materials

Key words: Pyramidal shaped ceria nano-biointerfaces, PLD, cells response [more]

Sodium Cholate Bile Acid-Stabilized Ferumoxytol-Doxorubicin-Lipiodol Emulsion for Transcatheter Arterial Chemoembolization of Hepatocellular Carcinoma

K Kwak, B Yu, SK Mouli, AC Larson, DH Kim

Journal of Vascular and Interventional Radiology (Elsevier) USA, 06 August 2020

Oncology

[more]

Light‐emitting diode irradiation induces AKT/mTOR‐mediated apoptosis in human pancreatic cancer cells and xenograft mouse model

YM Kim, SH Ko, YI Shin, Y Kim, T Kim, J Jung, SY Lee, NG Kim, KJ Park, JH Ryu

Journal of Cellular Physiology (Wiley Online Library) South Korea, 04 August 2020

Oncology

Key words: AKT/mTOR pathway, apoptosis, LED irradiation, pancreatic cancer, tumor growth [more]

Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor

Mayank Srivastava, Ying Zhang, Jian Chen, Devika Sirohi, Andrew Miller, Yang Zhang, Zhilu Chen, Haojie Lu, Jianqing Xu, Richard J. Kuhn & W. Andy Tao

Nature communications (Nature) USA, China, 04 August 2020

Virology

Key words: Chemical tools, Proteomics, Virus–host interactions [more]

Preclinical investigation of ovatodiolide as a potential inhibitor of colon cancer stem cells via downregulating sphere-derived exosomal β-catenin/STAT3/miR-1246 cargoes

YJ Huang, TH Huang, VK Yadav, M Rachmawati Sumitra, DTW Tzeng, PL Wie, JW Shih, ATH Wu

American Journal of Cancer Research (e-Century Publishing Corporation) Taiwan, China, 01 August 2020

Oncology

Key words: Colon cancer stem cells, tumor microenvironment, 5-FU resistance, tumorsphere derived exosomes, β-catenin/STAT3/miR-1246 signaling, and ovatodiolide [more]

Endocrine-disrupting chemicals rapidly affect intercellular signaling in Leydig cells

A Yawer, E Sychrová, P Labohá, J Raška, T Jambor, P Babica, I Sovadinová

Toxicology and Applied Pharmacology (Elsevier) Czech Republic, Slovakia, 31 July 2020

Endocrinology

Key words: Connexins, Endocrine-disrupting chemicals, Gap junctional intercellular communication, Leydig cells, Reproductive toxicants, Steroidogenesis [more]

Expression of Melatonin Receptor 1 in Rat Mesenteric Artery and Perivascular Adipose Tissue and Vasoactive Action of Melatonin

L Molcan, A Maier, A Zemančíková, K Gelles, J Török, M Zeman, I Ellinger

Cellular and Molecular Neurobiology (Springer) Slovakia, Austria, 30 July 2020

Cardiology

Key words: Rat melatonin receptor MT1, Melatonin, Mesenteric artery (MA), Perivascular fat tissue (PVAT), Neurogenic contraction [more]

Hydroxysafflor Yellow A Protects Against Myocardial Ischemia/Reperfusion Injury via Suppressing NLRP3 Inflammasome and Activating Autophagy

J Ye, S Lu, M Wang, W Ge, H Liu, Y Qi, J Fu, Q Zhang, B Zhang, G Sun, X Sun

Frontiers in Pharmacology (Frontiers Media S.A.) China, 30 July 2020

Cardiology

Key words: myocardial ischemia reperfusion injury, hydroxysafflor yellow A, NLRP3, autophagy, AMPK [more]

A Curcumin Analog Exhibits Multiple Biologic Effects on the Pathogenesis of Alzheimer's Disease and Improves Behavior, Inflammation, and β-Amyloid Accumulation in a Mouse Model

IJ Su, HY Chang, HC Wang, KJ Tsai

International Journal of Molecular Sciences (MDPI) Taiwan, 30 July 2020

Neuroscience

Key words: Alzheimer’s disease therapy, curcumin analog, TML-6, aging, bioavailability [more]

NHF-derived carbon dots: prevalidation approach in breast cancer treatment

Crina Elena Tiron, Gabriel Luta, Mihail Butura, Florin Zugun-Eloae, Corneliu S. Stan, Adina Coroaba, Elena-Laura Ursu, Gabriela Dumitrita Stanciu & Adrian Tiron

Scientific Reports (Nature) Romania, 29 July 2020

Oncology

Key words: Cancer, Drug development, Medical research, Oncology, Preclinical research, Translational research [more]

BMI1-Mediated Pemetrexed Resistance in Non-Small Cell Lung Cancer Cells Is Associated with Increased SP1 Activation and Cancer Stemness

HT Shen, PJ Chien, SH Chen, GT Sheu, MS Jan, BY Wang, WW Chang

Cancers (MDPI) Taiwan, 27 July 2020

Oncology

Key words: BMI1, SP1, pemetrexed resistance, non small cell lung cancer, cancer stem cells, epithelial–mesenchymal transition [more]

A general method to optimize and functionalize red-shifted rhodamine dyes

JB Grimm, AN Tkachuk, L Xie, H Choi, B Mohar, N Falco, K Schaefer, R Patel, Q Zheng, Z Liu, J Lippincott-Schwartz, TA Brown, LD Lavis

Nature methods (Nature) USA, 27 July 2020

Biological Methods

Key words: Chemical biology, Chemical tools, Fluorescence imaging, Imaging [more]

Ready to go 3D? A semi-automated protocol for microwell spheroid arrays to increase scalability and throughput of 3D cell culture testing

A Basu, A Dydowiczová, JE Trosko, L Bláha, P Babica

Toxicology Mechanisms and Methods (Taylor & Francis) Czech Republic, USA, 26 July 2020

Biological Methods

[more]

Imaging of metabolic activity adaptations to UV stress, drugs and differentiation at cellular resolution in skin and skin equivalents–Implications for oxidative UV damage

C Kremslehner, A Miller, R Nica, IM Nagelreiter, MS Narzt, B Golabi, V Vorstandlechner, M Mildner, J Lachner, E Tschachler, F Ferrara, K Klavins, M Schlosserer, J Grillari, A Haschemi, F Gruber

Redox Biology (Elsevier) Austria, Italy, USA, 19 July 2020

Dermatology

[more]

Neutrophil Extracellular Trap Degradation by Differently Polarized Macrophage Subsets

P Haider, JB Kral-Pointner, J Mayer, M Richter, C Kaun, C Brostjan, W Ellenberg, MB Fischer, WS Spledl, C Hengstenberg, K Huber, J Wojta, P Hohensinner

Arteriosclerosis,Thrombosis, and Vascular Biology (American Heart Association) Austria, 16 July 2020

Cardiology

Key words: aortic aneurysm, extracellular traps, humans, macrophages, thrombosis [more]

Enterocyte-Based Bioassay via Quantitative Combination of Proinflammatory Sentinels Specific to 8-keto-trichothecenes

SH Park, Y Moon

Frontiers in Immunology (Frontiers Media S.A.) South Korea, 16 July 2020

Immunology

Key words: 8-keto-trichothecene, ribotoxic stress, inflammation, epithelium, reporter biomonitoring [more]

Pre-and post-irradiation mild hyperthermia enabled by NIR-II for sensitizing radiotherapy

Q Li, L Hang, W Jiang, J Dou, L Xiao, X Tang, Y Yao, Y Wang

Biomaterials (Elsevier) China, 14 July 2020

Biological Materials

Key words: Au nanobipyramids, Second near-infrared window, Mild hyperthermia, Radiotherapy [more]

Antidiabetic activity in vitro and in vivo of BDB, protein tyrosine phosphatase 1B selective inhibitor from Rhodonela conferviodes

J Luo, M Zheng, B Jiang, C Li, S Guo, L Wang, X Li, R Yu, D Shi

British Journal of Pharmacology (Wiley) China, 14 July 2020

Pharmacology

Key words: Bromophenol, PTP1B inhibitor, Selectivity, Cell permeability, oral bioavailability [more]

Multivalent Clustering of Adhesion Ligands in Nanofiber-Nanoparticle Composites

D Dems, R Freeman, T Coradin, SI Stupp, C Aime

Acta Biomaterialia (SSRN) France, USA, 13 July 2020

Biological Materials

Key words: Peptide amphiphile, silica particles, nanobiocomposites, hybrid biomaterials, clustering [more]

Lycopene Inhibit IMQ-Induced Psoriasis-Like Inflammation by Inhibiting ICAM-1 Production in Mice

CM Shih, CK Hsieh, CY Huang, CY Huang, KH Wang, TH Fong, NTT Trang, KT Liu, AW Lee

Polymers (MDPI) Taiwan, 09 July 2020

Dermatology

Key words: lycopene, psoriasis [more]

Using Cytometry for Investigation of Purinergic Signaling in Tumor‐Associated Macrophages

VF Arnaud‐Sampaio, ILA Rabelo, CA Bento, T Glaser, J Bezerra, R Coutinho-Silva, H Ulrich, C Lameu

Cytometry Part A (Wiley) Brazil, 07 July 2020

Oncology

Key words: macrophage, TAM, cancer stem cells, purines, ATP, purinergic system, EMT, image cytometry [more]

Multimodal single‐cell analysis reveals distinct radioresistant stem‐like and progenitor cell populations in murine glioma

J Alexander, QC LaPlant, SS Pattwell, F Szulzewsky, PJ Cimino, FP Caruso, P Pugliese, Z Chen, F Chardon, AJ Hill, C Spurrell, D Ahrendsen, A Pietras, LM Starita, D Hambardzumyan, A Iavarone, J Shendure, EC Holland

Glia (Wiley) USA, Italy, Sweden, 04 July 2020

Neuroscience

Key words: glioma, glioma stem cells, myeloid cells, radiation response, radioresistance, single‐cell RNA sequencing, SP analysis [more]

Catching Common Cold Virus with a Net: Pyridostatin Forms Filaments in Tris Buffer That Trap Viruses—A Novel Antiviral Strategy?

A Real-Hohn, R Zhu, H Ganjian, N Ibrahim, P Hinterdorfer, H Kowalski, D Blaas

Viruses (MDPI) Austria, Sweden, 04 July 2020

Virology

Key words: Enterovirus, Rhinovirus, pyridostatin, filament, extracellular traps [more]

Fewer tumour-specific PD-1+ CD8+ TILs in high-risk “Infiltrating” HPV− HNSCC

K Xu, Y Fu, Y Han, R Xia, S Xu, S Duan, Z Zhang, J Li

British Journal of Cancer (Nature) China, 03 July 2020

Oncology

Key words: Head and neck cancer, Tumour immunology [more]

Slug Is A Surrogate Marker of Epithelial to Mesenchymal Transition (EMT) in Head and Neck Cancer

TB Steinbichler, J Dudas, J Ingruber, R Glueckert, S Sprung, F Fleischer, N Cidlinsky, D Dejaco, B Kofler, AI Giotakis, II Skvortsova, H Riechelmann

Journal of Clinical Medicine (MDPI) Austria, 30 June 2020

Oncology

Key words: image cytometry, p16, p53, cancer stem cells, E-cadherin, β-catenin, EMT, head and neck cancer [more]

Functional characterization of the basal amygdala-dorsal BNST pathway during contextual fear conditioning

JS Russell, S Trouche, LG Reijmers

eNeuro (Society for Neuroscience) USA, 29 June 2020

Neuroscience

Key words: contextual fear, fear memorybasal amygdala, bed nucleus of the stria terminalis, neural circuits, encoding, fear engram [more]

Tissues derived from reprogrammed Wharton's jelly stem cells of the umbilical cord as a platform to study gestational diabetes mellitus

CM Kong, A Subramanian, SU Gan, A Biswas, B Ariff, CY Fong

Stem Cell Research (Elsevier) Singapore, 26 June 2020

Stem Cell Research

Key words: Gestational diabetes mellitus, Induced pluripotent stem cells, Reprogramming, Wharton’s jelly stem cells, Pancreatic cells [more]

Comparison between paramagnetic and CD71 magnetic activated cell sorting of fetal nucleated red blood cells from the maternal blood

D Nemescu, D Constantinescu, V Gorduza, A Carauleanu, L Caba, DB Navolan

Journal of Clinical Laboratory Analysis (Wiley) Romania, 25 June 2020

Biological Methods

Key words: CD71, fluorescent in situ hybridization, magnetic‐activated cell sorting, nucleated red blood cells, prenatal diagnosis [more]

BMI1-KLF4 axis deficiency improves responses to neoadjuvant concurrent chemoradiotherapy in patients with rectal cancer

YC Hsu, CW Luo, WL Huang, CC Wu, CL Chou, CI Chen, SJ Chang, CY Chai, HC Wang, TY Chen, CF Li, MR Pan

Radiotherapy and Oncology (Elsevier) Taiwan, 24 June 2020

Radiotherapy, Oncology

Key words: BMI1, CCRT, Rectal cancers, Radioresistance [more]

The chemokine lymphotactin and its recombinant variants in oral cancer cell regulation

AZ Abdullah Zubir, SA Whawell, TS Wong, SA Khurram

Oral Diseases (Wiley) UK, 19 June 2020

Oncology

Key words: Cancer‐associated fibroblast, Lymphotactin, Oral squamous cell carcinoma, Tumour microenvironment, XCR1 [more]

p16 in highly malignant esophageal carcinomas: the correlation with clinicopathological factors and human papillomavirus infection

H Ishida, A Kasajima, F Fujishima, R Akaishi, S Ueki, Y Yamazaki, Y Onodera, X Gao, H Okamoto, Y Taniyama, T Kamei, H Sasano

Virchows Archiv (Springer) Japan, Australia, Germany, 16 June 2020

Oncology

Key words: Esophagus Small-cell carcinoma, Poorly differentiated squamous cell carcinoma, Basaloid squamous cell carcinoma, p16, Human papillomavirus [more]

p16 in highly malignant esophageal carcinomas: the correlation with clinicopathological factors and human papillomavirus infection

H Ishida, A Kasajima, F Fujishima, R Akaishi, S Ueki, Y Yamazaki, Y Onodera, X Gao, H Okamoto, Y Taniyama, T Kanei, H Sasano

Virchows Archiv (Springer) Japan, Australia, Germany, 16 June 2020

Oncology

Key words: Esophagus, Small-cell carcinoma, Poorly differentiated squamous cell carcinoma, Basaloid squamous cell carcinoma, p16, Human papillomavirus [more]

Reciprocal Regulation Between Indoleamine 2, 3-Dioxigenase 1 and Notch1 Involved in Radiation Response of Cervical Cancer Stem Cells

HY Low, YC Lee, YJ Lee, HL Wang, YI Chen, PJ Chien, ST Li, WW Chang

Cancers (MDPI) Taiwan, 12 June 2020

Oncology, Stem Cell Research

Key words: IDO1, notch1, radiation, cervical cancer, cancer stem cells [more]

Tumor Microenvironment Targeting Nano–Bio Emulsion for Synergistic Combinational X‐Ray PDT with Oncolytic Bacteria Therapy

W Park, S Cho, D Kang, JH Han, JH Park, B Lee, J Lee, DH Kim

Advanced Healthcare Materials (Wiley) South Korea, USA, 11 June 2020

Oncology, Nanomedicine

Key words: Bacteriolytic therapy, Nano–bio emulsions, Scintillating nanoparticles, Tumor microenvironments, X‐ray photodynamic therapy (PDT) [more]