Customer Publications (A total of 1683 papers published)
Development of a DsRed-expressing HepaRG cell line for real-time monitoring of hepatocyte-like cell differentiation by fluorescence imaging, with application in screening of novel geometric microstructured cell growth substrates
Biomedical Microdevices (Springer) Romania, 09 January 2017
Biological Methods
Key words: HepaRG, Hepatocyte-like cells, HBV, Differentiation, Microstructured PDMS [more]
Organism: Human
Cell Line: HepaRG, HeLa, Me290 cells
Inhibition of the transcriptional repressor complex Bcl-6/BCoR induces endothelial sprouting but does not promote tumor growth
Oncotarget (Impact Journals) Austria, 03 January 2017
Oncology
Key words: 79-6, Bcl-6, BCoR, colorectal carcinoma, vascular sprouting [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Limited tumor tissue drug penetration contributes to primary resistance against angiogenesis inhibitors
Theranostics (NCBI) Hungary, Austria, Sweden, 01 January 2017
Oncology
Key words: matrix assisted laser desorption ionization, imaging mass spectrometry, angiogenesis, receptor tyrosine kinase inhibitor, resistance, cancer [more]
Organism: Mouse
Tissue: Colon
Pathological State: Cancer
Heme Oxygenase-1-Expressing Dendritic Cells Promote Foxp3+ Regulatory T Cell Differentiation and Induce Less Severe Airway Inflammation in Murine Models
PLoS One (PLOS) Taiwan, 29 December 2016
Immunology
Key words: Dendritic cells (DCs), HO-1, lipopolysaccharide (LPS), Foxp3+ [more]
Organism: Mouse
Tissue: Lung
Interstitial Fibrosis, Functional Status, and Outcomes in Heart Failure With Preserved Ejection Fraction
Circulation:Cardiovascular Imaging (AHA Journals) Austria, 14 December 2016
Cardiology
Key words: Magnetic resonance imaging, heart failure, mapping [more]
Organism: Human
Tissue: Heart
Pathological State: Heart Failure
Adipose tissue–derived mesenchymal stem cells expressing prodrug-converting enzyme inhibit human prostate tumor growth
Molecular Therapy (Cell Press) Austria, Slovakia, 14 December 2016
Stem Cell Research
Mesenchymal Stem Cells Correct Inappropriate Epithelial–mesenchyme Relation in Pulmonary Fibrosis Using Stanniocalcin-1
Molecular Therapy (Cell Press) Japan, 14 December 2016
Pulmonology
Key words: Mesenchymal Stem Cells, Epithelial–mesenchyme Relation, Pulmonary Fibrosis, Stanniocalcin-1 [more]
Organism: Mouse
Tissue: Lung
Pathological State: Fibrosis
Early dissemination seeds metastasis in breast cancer
Nature (Nature) Germany, 14 December 2016
Oncology
Key words: Metastatic dissemination, breast cancer, HER2 , Karyotypic and phenotypic analysis [more]
Organism: Mouse
Tissue: Breast
Pathological State: Cancer
Cell-Based Delivery of Interleukin-13 Directs Alternative Activation of Macrophages Resulting in Improved Functional Outcome after Spinal Cord Injury
Stem Cell Reports (Elsevier) Belgium, 13 December 2016
Transplantation Medicine
Key words: Mesenchymal stem cells, interleukin-13, spinal cord injury, cell transplantation, microglia, macrophages [more]
Organism: Mouse
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
The 6-chromanol derivate SUL-109 enables prolonged hypothermic storage of adipose tissue-derived stem cells
Biomaterials (Elsevier) The Netherlands, 09 December 2016
Biological Materials
Key words: Adipose tissue-derived stem cells (ASC), Hypothermia, Cold storage, Mitochondrial damage, Chromanol [more]
Organism: Human
Cell Line: Adipose tissue derived stromal cells (ADSC)
Involvement of Pancreatic Stellate Cells in Regeneration of Remnant Pancreas after Partial Pancreatectomy
PLoS One (PLOS) Japan, 09 December 2016
Regenerative Medicine
Key words: Pancreatectomy, siRNA, activated pancreas stellate cells (aPSCs), apoptosis [more]
Organism: Rat
Tissue: Pancreas
Pathological State: Pancreatectomy
Nrf2 exerts cell-autonomous antifibrotic effects: compromised function in systemic sclerosis and therapeutic rescue with a novel heterocyclic chalcone derivative
Translational Research (Elsevier) USA, 09 December 2016
Neuroscience
Key words: Nrf2-nuclear factor erythroid 2–related factor 2, systemic sclerosis, TGF-β, CDDO, TMC [more]
Organism: Human
Tissue: Skin
Pathological State: Systemic Sclerosis
Lead-Free Piezoelectric (Ba,Ca)(Zr,Ti)O3 Thin Films for Biocompatible and Flexible Devices
Applied Materials and Interfaces (ACS Publications) Romania, 08 December 2016
Biological Materials
Key words: Biocompatible materials, laser processing, lead-free thin films, mesenchymal stem cells, osteogenic differentiation [more]
Organism: Human
Pathological State: Cancer
Cell Line: HEK 293T and A375 cells (Human epithelial embryonic kidney and human malignant melanoma cells)
Silica-Coated Metal Chelating-Melanin Nanoparticles as a Dual-Modal Contrast Enhancement Imaging and Therapeutic Agent
Applied Materials and Interfaces (ACS Publications) USA, 08 December 2016
Nanomedicine
Key words: Fluorescence imaging, melanin, metal-chelation,MRI, multimodal image-guidance, silica coating [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Nodal metastasis signatures in breast cancer
Pathology - Research and Practice (Elsevier) South Korea, 05 December 2016
Oncology
Key words: Breast cancer, node positive ratio, node positive number, ERK, WDR1, c-MET [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
Solid stress and elastic energy as measures of tumour mechanopathology
Nature Biomedical Engineering (Nature) USA, 28 November 2016
Neuroscience
Key words: Solid stress, tissue stiffness, tumour [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Mast Cells Are Abundant in Primary Cutaneous T-Cell Lymphomas: Results from a Computer-Aided Quantitative Immunohistological Study
PLoS One (PLOS) Austria, 28 November 2016
Oncology
Key words: Mast cells, cutaneous T-cell lymphomas (CTCL), haematopoetic cells [more]
Organism: Human
Tissue: Skin
Pathological State: Cancer
Cardiac extracellular matrix is associated with adverse outcome in patients with chronic heart failure
European Journal of Heart Failure (Wiley) Austria, 27 November 2016
Cardiology
Key words: Extracellular matrix (ECM), heart failure (HF), endomyocardial biopsy [more]
Organism: Human
Tissue: Heart
Pathological State: Heart Failure
Antimicrobial polycaprolactone/ polyethylene glycol embedded lysozyme coatings of Ti implants for osteoblast functional properties in tissue engineering
Applied Surface Science (Elsevier) Romania, 19 November 2016
Immunology
Key words: MAPLE, Dip coating, Lysozyme, Blends, Antimicrobial, Biocompatible [more]
Organism: Human
Cell Line: Primary osteogenic sarcoma cells (SAOS2), Human mesenchymal stem cells (hMSCs)
Rhinophototherapy in persistent allergic rhinitis
European Archives of Oto-Rhino-Laryngology (Springer) Hungary, 18 November 2016
Allergy Research
Key words: Intercellular adhesion molecule-1 expression, Intranasal phototherapy, Mucociliary clearance, Nasal inspiratory peak flow, Persistent allergic rhinitis, Rhinolight [more]
Organism: Human
Tissue: Mucosa
Pathological State: Allergy
The plasma membrane Ca2+ pump PMCA4b inhibits the migratory and metastatic activity of BRAF mutant melanoma cells
International Journal of Cancer (Wiley) Austria, 17 November 2016
Oncology
Key words: Ca2+, PMCA4b expression, NRAS mutant melanoma cells [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Intracerebral transplantation of interleukin 13-producing mesenchymal stem cells limits microgliosis, oligodendrocyte loss and demyelination in the cuprizone mouse model
Journal of Neuroinflammation (Springer) Belgium, 09 November 2016
Neuroscience
Key words: Interleukin 13, Mesenchymal stem cells, Neuroinflammation, Transplantation, Magnetic resonance imaging [more]
Organism: Mouse
Tissue: Brain
Pathological State: Demyelination
Dysregulation of Rab37-Mediated Cross-talk between Cancer Cells and Endothelial Cells via Thrombospondin-1 Promotes Tumor Neovasculature and Metastasis
Clinical Cancer Research (AACR Publications) Taiwan, 07 November 2016
Oncology
Key words: Rab37-Mediated, Thrombospondin-1, angiogenesis marker CD31, p-FAK/p-paxillin/p-ERK [more]
Organism: Human
Tissue: Esophagus
Pathological State: Cancer
Asxl2−/− Mice Exhibit De Novo Cardiomyocyte Production during Adulthood
Journal of Developmental Biology (MDPI) USA, 03 November 2016
Reproductive Medicine
Key words: heart, cardiogenic, cardiomyocyte, proliferation, regeneration, chromatin factor, epigenetic [more]
Organism: Mouse
Cell Line: Cardiomyocytes
A Single Postnatal Dose of Dexamethasone Enhances Memory of Rat Pups Later in Life
PLoS One (PLOS) Taiwan, 31 October 2016
Neuroscience
Key words: Postnatal dexamethasone (Dex) therapy, NMDAR, bronchopulmonary dysplasia, chronic lung disease [more]
Organism: Rat
Tissue: Brain
Cell Line Macroarray: An Alternative High-Throughput Platform to Analyze hiPSC Lines
Journal of Histochemistry and Cytochemistry (SAGE Journals) Italy, Austria, 26 October 2016
Biological Methods
Key words: cell line macroarray, high-throughput screening and quantification, hiPSC clones [more]
Organism: Human
Cell Line: hiPSCs
An Alternative High-Throughput Platform to Analyze hiPSC Lines
Journal of Histochemistry and Cytochemistry (SAGE Journals) Italy, Austria, 26 October 2016
Biological Methods
Key words: Cell line macroarray, high-throughput screening and quantification, hiPSC clones [more]
Organism: Human
Cell Line: Induced pluripotent cells (iPSCs)
Selective targeting of CREB-binding protein/β-catenin inhibits growth of and extracellular matrix remodelling by airway smooth muscle
British Journal of Pharmacology (Wiley) USA, The Netherlands, 25 October 2016
Pharmacology
Key words: Asthma, β-catenin, CREB-binding protein (CBP) , TGFβ1 [more]
Organism: Mouse
Tissue: Lung
KLF6 Suppresses Metastasis of Clear Cell Renal Cell Carcinoma via Transcriptional Repression of E2F1
Molecular Cancer Research (AACR Publications) China, 25 October 2016
Oncology
Key words: KLF6 expression, E2F1-mediated epithelial–mesenchymal, cell renal cell carcinoma (ccRCC) [more]
Organism: Mouse
Tissue: Lung
Pathological State: Cancer
TRPV1 attenuates intracranial arteriole remodeling through inhibiting VSMC phenotypic modulation in hypertension
Histochemistry and Cell Biology (Springer) China, 24 October 2016
Cardiology
Key words: TRPV1, Intracranial arteriole, VSMC, Phenotypic modulation, Hypertension [more]
Organism: Mouse, Rat
Tissue: Blood Vessels, Brain
PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer
Nature Medicine (Nature) UK, 24 October 2016
Oncology
Key words: Triple-negative breast cancers (TNBCs), PIM1 proto-oncogene, anti-apoptotic factor BCL2, dynamic BH3 [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Oncolytic influenza A virus expressing interleukin-15 decreases tumor growth in vivo
Surgery (Elsevier) Austria, 21 October 2016
Immunology
Key words: Interleukin-15, A virus, T cells, [more]
Organism: Mouse
Tissue: Allograft Tumor
Pathological State: Cancer
The fractionation of adipose tissue procedure to obtain stromal vascular fractions for regenerative purposes
Wound Repair and Regeneration (Wiley) The Netherlands, 21 October 2016
Regenerative Medicine
Key words: Autologous adipose tissue transplantation, FAT-stromal vascular fraction [more]
Organism: Human
Cell Line: Smooth muscle cells (SMCs)
Distinct Differences on Neointima Formation in Immunodeficient and Humanized Mice after Carotid or Femoral Arterial Injury
Scientific Reports (Nature) USA, The Netherlands, 19 October 2016
Cardiology
Key words: NOD.Cg-PrkdcscidIL2rgtm1Wjl(NSG), Percutaneous coronary interventions (PCIs), BL/6 mice [more]
Organism: Human
Cell Line: Peripheral blood mononuclear cell
In Situ Characterization of Tissue-Resident Immune Cells by MALDI Mass Spectrometry Imaging
Journal of Proteome Research (ACS Publications) Austria, 18 October 2016
Immunology
Key words: Colon tissue, immune cells, immunohistochemistry, lymphocytes, macrophages, MALDI mass spectrometry imaging, monocytes [more]
Organism: Human
Tissue: Colon
Aberrant expression of tumor-associated carbohydrate antigen Globo H in thyroid carcinoma
Journal of Surgical Oncology (Wiley) Taiwan, 18 October 2016
Oncology
Key words: Globo H - hexasaccharide glycosphingolipid, Normal or benign thyroid, papillary thyroid cancer [more]
Organism: Human
Tissue: Thyroid
Pathological State: Cancer
Oncostatin M‐preconditioned mesenchymal stem cells alleviate bleomycin‐induced pulmonary fibrosis through paracrine effects of the hepatocyte growth factor
Stem Cells Translational Medicine (Wiley) Taiwan, Malaysia, 18 October 2016
Stem Cell Research
Key words: Bleomycin-induced pulmonary fibrosis, Hepatocyte growth factor, Oncostatin M, Preconditioning, Stem cells [more]
Organism: Mouse
Tissue: Lung
Pathological State: Fibrosis
Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation
Cell Death & Disease (Nature) Austria, UK, Germany, 13 October 2016
Oncology
Key words: Apoptosis, Bone cancer, Cell signalling, Sarcoma [more]
Organism: Mouse
Tissue: Whole Organism
Ustekinumab treatment in severe atopic dermatitis: Down-regulation of T-helper 2/22 expression
Journal of the American Academy of Dermatology (Elsevier) Austria, 13 October 2016
Dermatology
Key words: Anti-interleukin-12/-23 p40, atopic dermatitis, cytokines, eczema, inflammatory, T helper 2, T helper 17, T helper 22, ustekinumab [more]
Organism: Human
Tissue: Skin
Pathological State: Dermatitis
Intraarticular overexpression of Smad7 ameliorates experimental arthritis
Scientific Reports (Nature) Taiwan, 12 October 2016
Immunology
Key words: Genetic vectors, Translational immunology [more]
Organism: Human
Tissue: Bone, Connective Tissue
Hydroxyapatite thin films grown by pulsed laser deposition and matrix assisted pulsed laser evaporation: Comparative study
Applied Surface Science (Elsevier) Romania, 11 October 2016
Regenerative Medicine
Key words: Pulsed laser deposition, Matrix assisted pulsed laser evaporation, Hydroxyapatite coatings, Biocompatibility, Cell proliferation and differentiation [more]
Organism: Human
Cell Line: Human mesenchymal stem cells (hMSCs)
Neuronal prolyl-4-hydroxylase 2 deficiency improves cognitive abilities in a murine model of cerebral hypoperfusion
Experimental Neurology (Elsevier) Germany, 05 October 2016
Neuroscience
Key words: HIF, PHD, Epo, VEGF, Hippocampus, Learning, Memory, Alzheimer's disease [more]
Organism: Mouse
Tissue: Brain
Pathological State: Cerebral Hypoperfusion
G-CSF-mobilized Bone Marrow Mesenchymal Stem Cells Replenish Neural Lineages in Alzheimer’s Disease Mice via CXCR4/SDF-1 Chemotaxis
Molecular Neurobiology (Springer) Taiwan, 05 October 2016
Neuroscience
Key words: G-CSF, Bone marrow stem cells, SDF-1CXCR4, Neurogenesis, Alzheimer’s disease [more]
Organism: Mouse
Tissue: Brain
Pathological State: Alzheimer’s Disease
Epithelial cholesterol deficiency attenuates human antigen R-linked pro-inflammatory stimulation via SREBP2-linked circuit
Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) South Korea, 04 October 2016
Gastroenterology
Key words: cholesterol regulation, inflammation, intestinal epithelium, intestinal metabolism, intestine, mRNA decay [more]
Organism: Mouse, Human
Tissue: Colon
Pathological State: Colitis
Houttuynia cordata Thunb Promotes Activation of HIF-1A–FOXO3 and MEF2A Pathways to Induce Apoptosis in Human HepG2 Hepatocellular Carcinoma Cells
Integrative Cancer Therapies (SAGE Journals) South Korea, 03 October 2016
Oncology
Key words: Cancer, cell apoptosis, hypoxia-inducible factor (HIF)-1A [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Hyperglycemia induces bioenergetic changes in adipose-derived stromal cells while their pericytic function is retained
Stem Cells and Development (Mary Ann Liebert Inc.) The Netherlands, Chile, 01 October 2016
Stem Cell Research
Key words: Adipose Derived Stromal Cells, Diabetic Retinopathy, Pericyte, Hyperglycemia [more]
Organism: Human
Cell Line: Adipose tissue derived stromal cells (ADSC)
NSAID-activated gene 1 mediates pro-inflammatory signaling activation and paclitaxel chemoresistance in type I human epithelial ovarian cancer stem-like cells
Histochemistry and Cell Biology (NCBI) South Korea, 30 September 2016
Oncology
Key words: NAG-1, epithelial ovary cancer, paclitaxel, NF-κB, chemoresistance [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
Interleukin-13 immune gene therapy prevents CNS inflammation and demyelination via alternative activation of microglia and macrophages
GLIA (Wiley) Belgium, 29 September 2016
Neuroscience
Key words: IL-13, microglia, macrophages, severe oligodendrocyte loss and demyelination, mouse nodel [more]
Organism: Mouse
Tissue: Brain
Pathological State: Demyelination
Comparison of cancer cells cultured in 2D vs 3D reveals differences in AKT/mTOR/S6-kinase signaling and drug response
Journal of Cell Science (The Company of Biologists) Austria, 23 September 2016
Oncology
Key words: Cancer cells, colon cancer, AKT/mTOR/S6-kinase, ERK phosphorylation [more]
Organism: Human
Cell Line: LS174T, HT29, SW620, HCT116), Caco2 and DLD1 (Human colon cancer cell lines)
Targeted multimodal nano-reporters for pre-procedural MRI and intra-operative image-guidance
Biomaterials (Elsevier) USA, 19 September 2016
Medical Imaging
Key words: Upconversion nanoparticles, Medical imaging, Cancer, Interventional radiology, Multimodal probe [more]
Organism: Rat
Tissue: Heart, Liver, Spleen, Lung, Kidney
CD103+ intraepithelial T cells in high-grade serous ovarian cancer are phenotypically diverse TCRαβ+ CD8αβ+ T cells that can be targeted for cancer immunotherapy
Oncotarget (Impact Journals) The Netherlands, 16 September 2016
Oncology
Key words: tumor-infiltrating lymphocytes, high-grade serous ovarian cancer, CD103, TGF-β, cancer immunotherapy [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
Expression and prognostic impact of immune modulatory molecule PD-L1 in meningioma
Journal of Neuro-Oncology (Springer) USA, 13 September 2016
Neuroscience
Key words: Meningioma, PD-L1, B7-H1, Immunotherapy, Checkpoint, Lymphocyte, Macrophage [more]
Organism: Human
Tissue: Brain
Pathological State: Cancer
Paricalcitol attenuates cardiac fibrosis and expression of endothelial cell transition markers in isoproterenol-induced cardiomyopathic rats
Critical Care Medicine (Ingentaconnect) Taiwan, 09 September 2016
Cardiology
Key words: cardiac fibrosis, cardiomyopathy, endothelial-to-mesenchymal cell transition, vitamin D activator [more]
Organism: Rat
Tissue: Heart
Pathological State: Fibrosis
The effects of oral and topical corticosteroid in rabbit corneas
BMC Ophthalmology (BioMed Central) Japan, 05 September 2016
Ophthalmology
Key words: Corticosteroid, Keratitis, Cornea, Wound healing, Pharmacokinetics [more]
Organism: Rabbit
Tissue: Eye
Pathological State: Skin Wound
Presentation of underglycosylated mucin 1 in pancreatic adenocarcinoma (PDAC) at early stages
American Journal of Cancer Research (NCBI) USA, 01 September 2016
Oncology
Key words: Pancreatic cancer, underglycosylated mucin 1, tumor antigen, immunohistochemistry [more]
Organism: Human
Tissue: Pancreas
Pathological State: Cancer
Neural stem cells secrete factors facilitating brain regeneration upon constitutive Raf-Erk activation
Scientific Reports (Nature) South Korea, 24 August 2016
Neuroscience
Key words: Neurology, neural stem cells, Raf-Erk pathway, radial glial cells [more]
Organism: Mouse
Tissue: Brain
Degradation of Kidney and Psoas Muscle Proteins as Indicators of Post-Mortem Interval in a Rat Model, with Use of Lateral Flow Technology
PLoS One (PLOS) South Korea, 23 August 2016
Forensic Science
Key words: Post-mortem interval (PMI) markers, kidney, muscle, GAPDH [more]
Organism: Rat
Tissue: Kidney, Muscle
Toward the Automated Detection and Characterization of Osteoclasts in Microscopic Images
Principles of Osteoimmunology (Springer) Austria, 19 August 2016
Medical Image Analysis
Key words: Osteoimmunology, microscopes, biological samples, automated image segmentation and analysis
LIN28A enhances the therapeutic potential of cultured neural stem cells in a Parkinson’s disease model
Brain: A journal of neurology (Oxford University Press) South Korea, 18 August 2016
Neuroscience
Key words: LIN28A, neural stem cell (NSC) culture, repair capacity, Parkinson’s disease [more]
Organism: Rat
Tissue: Brain
Pathological State: Parkinson's Disease
Dynamic Modulation of Microglia/Macrophage Polarization by miR-124 after Focal Cerebral Ischemia
Journal of Neuroimmune Pharmacology (Springer) Germany, 18 August 2016
Neuroscience
Key words: Stroke, Microglia/macrophage polarization, Pro-inflammatory and anti-inflammatory phenotypes, miRNA-124, Neuroinflammation [more]
Organism: Mouse
Tissue: Brain
Pathological State: Cerebral Ischemia
The antiviral alkaloid berberine reduces chikungunya virus-induced mitogen-activated protein kinase (MAPK) signaling
Journal of Virology (American Society for Microbiology) Finland, 17 August 2016
Virology
Key words: Chikungunya virus, non-toxic plant alkaloid berberine, mitogen-activated protein kinase [more]
Organism: Mouse
Tissue: Bone, Connective Tissue
Pathological State: Virus Infection
Bradykinin promotes neuron-generating division of neural progenitor cells via ERK activation
Journal of Cell Science (The Company of Biologists) Brazil, 15 August 2016
Neuroscience
Key words: Bradykinin, neurogenesis, TIS21 (PC3/BTG2) expression [more]
Organism: Mouse
Tissue: Brain
G9a/RelB regulates self-renewal and function of colon-cancer-initiating cells by silencing Let-7b and activating the K-RAS/β-catenin pathway
Nature Cell Biology (Nature) Taiwan, 15 August 2016
Oncology
Key words: Colorectal cancer, cancer-initiating cells phenotypes, K-RAS/β-catenin pathway [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Prevention of Colitis and Colitis-Associated Colorectal Cancer by a Novel Polypharmacological Histone Deacetylase Inhibitor
Clinical Cancer Research (AACR Publications) Taiwan, 14 August 2016
Oncology
Key words: Colorectal cancer, colitis, HDAC, HMGR [more]
Organism: Mouse
Tissue: Colon
Pathological State: Cancer
Localization of TrkB and p75 receptors in peritoneal and deep infiltrating endometriosis: an immunohistochemical study
Reproductive Biology and Endocrinology (Springer) Germany, 12 August 2016
Reproductive Medicine
Key words: Neurotrophins, BDNF, endometriosis, immunohistochemistry [more]
Organism: Human
Tissue: Endometrium
Pathological State: Endometriosis
Hypoxia-inducible factor-1α promotes glomerulosclerosis and regulates COL1A2 expression through interactions with Smad3
Kidney International (Elsevier) USA, 05 August 2016
Physiology
Key words: Fibrosis, glomerulus, hypoxia, TGF-β [more]
Organism: Mouse
Tissue: Kidney
Role of the immune system in the peritoneal tumor spread of high grade serous ovarian cancer
Oncotarget (Impact Journals) Austria, 03 August 2016
Oncology
Key words: epithelial ovarian cancer, peritoneal tumor spread, flow cytometry, PD-1, next generation sequencing [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
Sur8 mediates tumorigenesis and metastasis in colorectal cancer
Experimental and Molecular Medicine (Nature) South Korea, 29 July 2016
Oncology
Key words: Scaffold protein, Ras-extracellular signal-regulated kinase, doxycyline, HCT116 cells [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
CD271 regulates the proliferation and motility of hypopharyngeal cancer cells
Scientific Reports (Nature) Japan, 29 July 2016
Oncology
Key words: CD271 (p75 neurotrophin receptor), human hypopharyngeal cancer, head and neck squamous cell carcinoma [more]
Organism: Human
Pathological State: Cancer
Regulation of actin dynamics by WNT-5A: implications for human airway smooth muscle contraction
Scientific Reports (Nature) The Netherlands, 29 July 2016
Cell Biology
Key words: Airway hyperresponsiveness, asthm, intracellular calcium flux, actin polymerisation [more]
Organism: Human
Cell Line: Bronchial smooth muscle cells
Tissue-Resident CD169+ Macrophages Form a Crucial Front Line against Plasmodium Infection
Cell Reports (Cell Press) Singapore, 28 July 2016
Cell Biology
Key words: Plasmodium berghei ANKA, malaria, myeloid cells, macrophages [more]
Organism: Mouse
Tissue: Brain
Pathological State: Bacterial Infection
In situ mapping of innate lymphoid cells in human skin: evidence for remarkable differences between normal and inflamed skin
Journal of Investigative Dermatology (Elsevier) Austria, Switzerland, Romania, 22 July 2016
Dermatology
Key words: Lymphoid Cells, Human Skin, Inflamed Skin, atopic dermatitis, psoriasis [more]
Organism: Human
Tissue: Skin
Pathological State: Dermatitis, Psoriasis
4 – Proffered Paper: Immunological changes during tumor progression from primary to recurrent glioblastoma
European Journal of Cancer (Elsevier) , 14 July 2016
Oncology
Key words: Cancer, tumor, glioblastoma [more]
Organism: Human
Tissue: Brain
Pathological State: Cancer
Multimodal Imaging of Nanocomposite Microspheres for Transcatheter Intra-Arterial Drug Delivery to Liver Tumors
Scientific Reports (Nature) USA, 13 July 2016
Oncology
Key words: Biomedical materials, cancer imaging, hepatic artery, nanotechnology in cancer, targeted therapies [more]
Organism: Rat
Tissue: Xenograft Tumor, Liver
Pathological State: Cancer
Quantitative comparison and reproducibility of pathologist scoring and digital image analysis of estrogen receptor β2 immunohistochemistry in prostate cancer
Diagnostic Pathology (BioMed Central) USA, 11 July 2016
Pathology
Key words: Prostate cancer, Biomarkers, Digital pathology, Quantification, Estrogen receptor β2 [more]
Organism: Human
Tissue: Prostate
Pathological State: Cancer
Induction of Suppressor Cells and Increased Tumor Growth following Chronic Psychosocial Stress in Male Mice
PLoS One (PLOS) Germany, 08 July 2016
Neuroscience
Key words: Chronic subordinate colony, myeloid cells, hypothalamus-pituitary-adrenal, sympathetic nervous system [more]
Organism: Mouse
Tissue: Spleen, Allograft Tumor
Pathological State: Cancer
Lesional CD4+ IFN-γ+ cytotoxic T lymphocytes in IgG4-related dacryoadenitis and sialoadenitis
Annals of the Rheumatic Diseases (BMJ Journals) Japan, 29 June 2016
Rheumatology
Key words: IgG4-related disease, T lymphocytes, Sjögren's syndrome, [more]
Organism: Human
Tissue: Salivary Gland
Pathological State: Cancer
Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma
OncoImmunology (Taylor and Francis) Singapore, 21 June 2016
Oncology
Key words: Metabolism, macrophages, pancreatic cancer, metastasis [more]
Organism: Human
Pathological State: Cancer
Cell Line: HPAF-II (Pancreatic epithelial tumor cell line)
ICAM-1 Binding Rhinoviruses A89 and B14 Uncoat in Different Endosomal Compartments
Journal of Virology (American Society for Microbiology) Austria, 20 June 2016
Virology
Key words: Human rhinovirus A89 (HRV-A89) and HRV-B14, RNA genome, endocytic recycling compartment (ERC) [more]
Organism: Human
Pathological State: Cancer
Cell Line: HeLA cells
Validation of tumor protein marker quantification by two independent automated immunofluorescence image analysis platforms
Modern Pathology (Nature) USA, 17 June 2016
Medical Image Analysis
Key words: Histology, biomarkers, breast tumor
Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells
Nature Communications (Nature) Taiwan, 16 June 2016
Oncology
Key words: Biological sciences, cancer, cell biology [more]
Organism: Human, Mouse
Tissue: Colon, Xenograft Tumor
Pathological State: Cancer
A new fluorescence/PET probe for targeting intracellular human telomerase reverse transcriptase (hTERT) using Tat peptide-conjugated IgM
Biochemical and Biophysical Research Communications (Elsevier) South Korea, 15 June 2016
Biological Methods
Key words: Intracellular and intranuclear protein, hTERT, tat peptide, IgM antibody, 64Cu, Live cell imaging [more]
Organism: Human
Pathological State: Cancer
Cell Line: HT29, U2OS cells
Ribosome inactivation leads to attenuation of intestinal polymeric Ig receptor expression via differential regulation of human antigen R
The Journal of Immunology (American Association of Immunologists) South Korea, 15 June 2016
Immunology
Key words: Ribosome ,Polymeric Ig Receptor ,Differential Regulation, Human Antigen R [more]
Organism: Mouse
Tissue: Small Intestine, Colon
Development of a novel mouse model of hepatocellular carcinoma with nonalcoholic steatohepatitis using a high-fat, choline-deficient diet and intraperitoneal injection of diethylnitrosamine
BMC Gastroenterology (BioMed Central) Japan, 13 June 2016
Oncology
Key words: Nonalcoholic steatohepatitis, hepatocellular carcinoma, diethylnitrosamine, high-fat choline-deficient diet, mouse model [more]
Organism: Mouse
Tissue: Liver
Pathological State: Fibrosis
Automated muscle fiber type population analysis with ImageJ of whole rat muscles using rapid myosin heavy chain immunohistochemistry
Muscle and Nerve (Wiley) Austria, 13 June 2016
Medical Image Analysis
Key words: Automated muscle fiber analysis, fiber population, ImageJ, muscle fiber type, myosin heavy chain, rat [more]
Organism: Rat
Tissue: Muscle
Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation
Nature Chemical Biology (Nature) South Korea, 13 June 2016
Oncology
Key words: Cancer therapy, cell signalling, screening, small molecules [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Clonorchis sinensis omega-class glutathione transferases play major roles in the protection of the reproductive system during maturation and the response to oxidative stress
Parasites and Vectors (BioMed Central) South Korea, 13 June 2016
Parasitology
Key words: Clonorchis sinensis, glutathione transferase (GST), omega-class GST, sexual maturation, reproductive system, oxidative stress [more]
Organism: Flatworm
Tissue: Whole Organism
Amniotic Fluid Cells Proliferation in Normal and Down Syndrome Subjects
ARS Medica Tomitana (Sciendo) Romania, 11 June 2016
Reproductive Medicine
Key words: Down syndrome, Trisomy 21, amniotic fluid-derived stem cells, proliferation, cell cycle [more]
Organism: Human
Cell Line: Amniotic fluid derived cells
Epidermal desmoglein 1 expression is reduced in kidney transplant recipients compared to immunocompetent patients
Journal of Investigative Dermatology (Elsevier) USA, 11 June 2016
Dermatology
Key words: Calcineurin inhibitor, desmoglein, E-cadherin, epidermal growth factor receptor, histone deacetylase inhibitor, immunocompetent patient, K1/10, Keratin 1 or 10, kidney transplant recipient, mycophenolate mofitil, plakoglobin, squamous cell carcinoma,ultraviolet light [more]
Organism: Human
Tissue: Skin
Pathological State: Cancer
ApoE deficiency exacerbates the development and sustainment of a semi-chronic K/BxN serum transfer-induced arthritis model
Journal of Translational Medicine (BioMed Central) USA, 10 June 2016
Immunology
Key words: Arthritis, cholesterol, inflammation, animal models of human disease [more]
Organism: Mouse
Tissue: Bone, Connective Tissue
Pathological State: Atherosclerosis
Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells in vitro and in an orthotopic mouse model
Molecular Cancer (Springer) Taiwan, 10 June 2016
Oncology
Key words: Histone deacetylase inhibitor, radiation, triple-negative breast cancer, autophagy [more]
Organism: Mouse
Tissue: Breast
Pathological State: Cancer
Infiltration of Macrophages Correlates with Severity of Allograft Rejection and Outcome in Human Kidney Transplantation
PLoS One (PLOS) Germany, 10 June 2016
Transplantation Medicine
Key words: Macropaghes, T-lymphocytes, calcineriurin, inhibitor, renal transplantation [more]
Organism: Human
Tissue: Kidney
Pathological State: Organ Transplantation
Gain of BDNF Function in Engrafted Neural Stem Cells Promotes the Therapeutic Potential for Alzheimer’s Disease
Scientific Reports (Nature) Taiwan, 06 June 2016
Neuroscience
Key words: Dementia, neural stem cells, regeneration and repair in the nervous system, stem-cell research [more]
Organism: Mouse
Tissue: Brain
Pathological State: Alzheimer’s Disease
Non-invasive, neuron-specific gene therapy by focused ultrasound-induced blood-brain barrier opening in Parkinson's disease mouse model
Journal of Controlled Release (Elsevier) Taiwan, 26 May 2016
Neuroscience
Key words: Focused ultrasound, Gene therapy, Blood-brain barrier opening, Microbubbles, GDNF [more]
Organism: Mouse
Tissue: Brain
Pathological State: Parkinson's Disease
Functional studies on primary tubular epithelial cells indicate a tumor suppressor role of SETD2 in clear cell renal cell carcinoma
Neoplasia (Elsevier) The Netherlands, 26 May 2016
Oncology
Key words: Primary Tubular Epithelial Cells, Tumor Suppression, SETD2, Renal Cell Carcinoma [more]
Organism: Human
Pathological State: Cancer
Cell Line: PTECs and HKC8 cells
GBIQ: a non-arbitrary, non-biased method for quantification of fluorescent images
Scientific Reports (Nature) Japan, 23 May 2016
Medical Image Analysis
Key words: Image processing, software [more]
Organism: Mouse
Cell Line: MESCs (Mouse Embryonic stem cells)
The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas
Science (American Association for the Advancement of Science) USA, 20 May 2016
Oncology
Key words: Mouse models, glioblastoma multiforme, macrophage [more]
Organism: Mouse
Tissue: Lymphoid Tissue, Connective Tissue
Pathological State: Cancer
Knockout of ho-1 protects the striatum from ferrous iron-induced injury in a male-specific manner in mice
Scientific Reports (Nature) Taiwan, 20 May 2016
Neuroscience
Key words: Neuronal physiology, reproductive biology [more]
Organism: Mouse
Tissue: Ovaries, Penis, Testis
Anti-TGF-β Antibody, 1D11, Ameliorates Glomerular Fibrosis in Mouse Models after the Onset of Proteinuria
PLoS One (PLOS) USA, 17 May 2016
Nephrology
Key words: Renal fibrosis [more]
Organism: Mouse
Tissue: Kidney
Pathological State: Nephropathy
HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity
Biochemical Pharmacology (Elsevier) The Netherlands, 15 May 2016
Pharmacology
Key words: Lysine acetylation, HDACs, inflammation, NF-κB p65, HDAC inhibitors, lung disease [more]
Organism: Mouse
Tissue: Lung
Exploration of more effective neurorrhaphy in facial nerve reconstruction: A comparison focusing on the difference of neural window size and condition of the neurorrhaphy site
Journal of Plastic, Reconstructive and Aesthetic Surgery (Elsevier) Japan, 12 May 2016
Neuroscience
Key words: Nerve reconstruction, Facial palsy, Side to side, End to side, Rat [more]
Organism: Rat
Tissue: Brain
The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth
Oncotarget (Impact Journals) Austria, germany, USA, 12 May 2016
Oncology
Key words: STAT1, STAT3, colorectal cancer [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
MAL Is a Regulator of the Recruitment of Myelin Protein PLP to Membrane Microdomains
PLoS One (PLOS) The Netherlands, 12 May 2016
Neuroscience
Key words: Oligodendrocytes, myelin membrane, rat brain tissue [more]
Organism: Rat
Cell Line: Primary oligodendrocyte, OLN-93, HEPG2 cells
In situ hybridization to detect and localize signature cytokines of T-helper (Th) 1 and Th2 immune responses in chicken tissues
Veterinary Immunology and Immunopathology (Elsevier) Austria, 12 May 2016
Immunology
Key words: In situ hybridization, RNA probes, ChIFN-γ, ChIL-4, ChIL-13 [more]
Organism: Chicken
Tissue: Spleen, Liver
Pathological State: Parasitic Infection
Acidic pH-triggered drug-eluting nanocomposites for magnetic resonance imaging-monitored intra-arterial drug delivery to hepatocellular carcinoma
Applied Materials and Interfaces (ACS Publications) USA, South Korea, 09 May 2016
Nanomedicine, Oncology
Key words: hepatocellular carcinoma, image-guided therapy, iron oxide nanoparticles, nanocomposite microspheres, pH-responsive materials, sorafenib [more]
Organism: Rat
Tissue: Liver
Pathological State: Cancer
Interleukin-25 is detrimental for recovery after spinal cord injury in mice
Journal of Neuroinflammation (Springer) Belgium, 06 May 2016
Neuroscience
Key words: IL-25, type 2 immune response, spinal cord injury, basso mouse scale, locomotor recovery Th1 Th2 [more]
Organism: Mouse
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
CCR6 expression in colon cancer is associated with advanced disease and supports epithelial-to-mesenchymal transition
British Journal of Cancer (Nature) USA, 05 May 2016
Oncology
Key words: Colon cancer, Epithelial–mesenchymal transition, Metastasis, Tumour biomarkers [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
PPARγ inhibits VSMC proliferation and migration via attenuating oxidative stress through upregulating UCP2
PLoS One (PLOS) China, 04 May 2016
Cell Biology
Key words: Oxidative stress, Reactive oxygen species ,Carotid arteries ,Mitochondria ,Antioxidants ,MTT assay ,Fluorescence microscopy ,Growth factors [more]
Organism: Mouse
Tissue: Blood Vessels
Loss of HIF-1β in macrophages attenuates AhR/ARNT-mediated tumorigenesis in a PAH-driven tumor model
Oncotarget (Impact Journals) Germany, 03 May 2016
Oncology
Key words: xenobiotics, CYP1A1, DNA damage, breast cancer, fibrosarcoma [more]
Organism: Mouse
Tissue: Breast
Pathological State: Cancer
449 In situ mapping of innate lymphoid cells in normal and inflamed human skin
Journal of Investigative Dermatology (Elsevier) Austria, 01 May 2016
Immunology
Key words: Innate lymphoid cells, atopic dermatitis, psoriasis, normal human skin, immunofluorescence [more]
Organism: Human
Tissue: Skin
Pathological State: Dermatitis, Psoriasis
Paracrine Factors from Irradiated Peripheral Blood Mononuclear Cells Improve Skin Regeneration and Angiogenesis in a Porcine Burn Model
Scientific Reports (Nature) Austria, 29 April 2016
Regenerative Medicine
Key words: Drug development, regeneration, translational research, trauma [more]
Organism: Pig
Tissue: Skin
Pathological State: Burn Wound
SIRT2-mediated deacetylation and tetramerization of pyruvate kinase directs glycolysis and tumor growth
Cancer Research (AACR Publications) USA, 27 April 2016
Oncology
Key words: Mitochondria, pyruvate kinase, acetylation, mammary tumor cells [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
Benzyl butyl phthalate promotes breast cancer stem cell expansion via SPHK1/S1P/S1PR3 signaling
Oncotarget (Impact Journals) Taiwan, 26 April 2016
Oncology
Key words: Aryl hydrocarbon receptor, sphingosine kinase 1, sphingosine 1-phosphate, sphingosine-1-phosphate receptor 3, breast cancer stem cells [more]
Organism: Human
Pathological State: Cancer
Cell Line: MCF-7 cells (Breast Cancer Cell line)
Tumor-associated B cells in cutaneous primary melanoma and improved clinical outcome
Human Pathology (Elsevier) Austria, 20 April 2016
Pathology
Key words: CD20, prognosis, melanoma, tumor microenvironment, tumor-associated B cells (TAB), tumor-infiltrating lymphocytes [more]
Organism: Human
Tissue: Skin
Pathological State: Cancer
Effectiveness of a Layer-by-Layer Microbubbles-Based Delivery System for Applying Minoxidil to Enhance Hair Growth
Theranostics (Ivyspring International Publisher) Taiwan, 11 April 2016
Oncology
Key words: Microbubbles, ultrasound, transdermal drug delivery, minoxidil, chitosan oligosaccharide lactate, hair growth [more]
Organism: Pig, Mouse
Tissue: Skin
Biocompatibility Assessment of a New Biodegradable Vascular Graft via In Vitro Co-culture Approaches and In Vivo Model
Annals of Biomedical Engineering (Springer) Austria, 07 April 2016
Regenerative Medicine
Key words: Vascular graft, biocompatibility, biodegradable polyurethane, fibroblast-macrophage co-culture [more]
Organism: Rat
Tissue: Blood Vessels
Pathological State: Organ Transplantation
Dose-escalation study for the targeting of CD44v+cancer stem cells by sulfasalazine in patients with advanced gastric cancer (EPOC1205)
Gastric Cancer (Springer) Japan, 07 April 2016
Oncology
Key words: Cancer stem cellCD44 variant positiveGastric cancerSulfasalazinexCT [more]
Organism: Human
Tissue: Stomach
Pathological State: Cancer
Oxidative phosphorylation and mitochondrial function differ between human prostate tissue and cultured cells
FEBS Journal (FEBS PRESS) Austria, 06 April 2016
Cell Biology
Key words: electron transfer system, high‐resolution respirometry, mitochondria, oxidative phosphorylation, prostate metabolism [more]
Organism: Human
Tissue: Prostate
Cross-talk between DopaChromeTautomerase and Caveolin-1 is melanoma cell phenotype specific and potentially involved in tumor progression.
Journal of biological chemistry (American Society for Biochemistry and Molecular Biology) Romania, 06 April 2016
Oncology
Key words: Antigen processing, caveolin, epithelial-mesenchymal transition (EMT), melanoma, structural model [more]
Organism: Human
Tissue: Skin
Pathological State: Cancer
Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival
PNAS (PNAS) USA, 04 April 2016
Oncology
Key words: Anti-angiogenic therapy, tumor microenvironment, anti-tumor immunity, macrophage polarization, microglia reprogramming [more]
Organism: Mouse
Tissue: Brain
Pathological State: Cancer
CD103 defines intraepithelial CD8+ PD1+ tumour-infiltrating lymphocytes of prognostic significance in endometrial adenocarcinoma
European Journal of Cancer (Elsevier) The Netherlands, 31 March 2016
Oncology
Key words: Tumour-infiltrating lymphocytes, endometrial cancer, adenocarcinoma, CD103, survival [more]
Organism: Human
Tissue: Endometrium
Pathological State: Cancer
Combining ultrasound and lactobacilli treatment for high-fat-diet-induced obesity in mice
Journal of Animal Physiology and Animal Nutrition (Wiley) Taiwan, 29 March 2016
Physiology
Key words: Actobacilli, ultrasound, high-fat-diet-induced obesity mice, micro-CT, fat deposition [more]
Organism: Mouse
Tissue: Liver, Adipose Tissue
Pathological State: Obesity
Myeloid PTEN deficiency impairs tumor-immune surveillance via immune-checkpoint inhibition
OncoImmunology (Taylor and Francis) Austria, 28 March 2016
Immunology
Key words: Colitis-associated colon cancer, myeloid Pi3K, tumor immune-surveillance [more]
Organism: Mouse
Tissue: Xenograft Tumor, Colon
Pathological State: Cancer
Chemotherapy of Colorectal Liver Metastases Induces a Rapid Rise in Intermediate Blood Monocytes which Predicts Treatment Response
OncoImmunology (Taylor and Francis) Austria, 22 March 2016
Immunology
Key words: Chemotherapy, colorectal liver metastase, blood monocytes [more]
Organism: Human
Tissue: Liver
Pathological State: Cancer
A specific area of olfactory cortex involved in stress hormone responses to predator odours
Nature (Nature) USA, 21 March 2016
Neuroscience
Key words: Neural circuits, Olfactory cortex, Sensory processing [more]
Organism: Mouse
Tissue: Brain
MiRNA-124 induces neuroprotection and functional improvement after focal cerebral ischemia
Biomaterials (Elsevier) The Netherlands, 19 March 2016
Neuroscience
Key words: MicroRNA-124, ischemic stroke, immune cell modulation/polarization, neuroprotection, functional improvement, arginase-1 [more]
Organism: Mouse
Tissue: Brain
Pathological State: Cerebral Ischemia
Neuronal deficiency of HIF prolyl 4-hydroxylase 2 in mice improves ischemic stroke recovery in an HIF dependent manner
Neurobiology of Disease (Elsevier) Germany, 19 March 2016
Neuroscience
Key words: PHD2, HIF, neuron, focal cerebral ischemia, hypoxia, VEGF, angiogenesis [more]
Organism: Mouse
Tissue: Brain
Pathological State: Cerebral Ischemia
Unfractionated bone marrow cells attenuate paraquat-induced glomerular injury and acute renal failure by modulating the inflammatory response
Scientific Reports (Nature) Taiwan, 18 March 2016
Nephrology
Key words: Acute kidney injury, Bone marrow transplantation [more]
Organism: Mouse
Tissue: Kidney
Pathological State: Kidney Injury
High Resolution Ultrasonography for Assessment of Renal Cysts in the PCK Rat Model of Autosomal Recessive Polycystic Kidney Disease
Kidney and Blood Pressure Research (Karger) Switzerland, 17 March 2016
Nephrology
Key words: High resolution diagnostic imaging, Total cyst volume, Polycystic kidney disease, PCK rat, Total kidney volume [more]
Organism: Rat
Tissue: Kidney
Pathological State: Polycystic Kidney Disease
Efficient generation of smooth muscle cells from adipose-derived stromal cells by 3D mechanical stimulation can substitute the use of growth factors in vascular tissue engineering
Biotechnology Journal (Wiley) The Netherlands, 15 March 2016
Regenerative Medicine
Key words: Adipose tissue-derived stromal cells (ASC), poly(1,3-trimethylene carbonate) (PTMC), smooth muscle cells (SMC), transforming Growth Factor beta 1 (TGF-ß1), vascular tissue engineering [more]
Organism: Human
Cell Line: HUVECs, ASC (Human umbilical vein endothelial cells, Adipose tissue derived stromal cells)
OX40 ligand newly expressed on bronchiolar progenitors mediates influenza infection and further exacerbates pneumonia
EMBO Molecular Medicine (Wiley) Japan, 14 March 2016
Pathology
Key words: Bronchioles, glycosylation regeneration, OX40 ligand, viral pneumonia [more]
Organism: Dog
Pathological State: Virus Infection
Cell Line: MDCK cells
Internalization of nanopolymeric tracers does not alter characteristics of placental cells
Journal of Cellular and Molecular Medicine (Wiley) Italy, 14 March 2016
Cell Biology
Key words: Cell tracing, nanoparticles, mesenchymal stem/stromal cells, placenta, amnion, chorion, hypoxia, ischaemia [more]
Organism: Human
Tissue: Placenta
In primary Sjögren's syndrome high absolute numbers and proportions of B cells in parotid glands predict responsiveness to rituximab as defined by ESSDAI, but not by SSRI
Annals of the Rheumatic Diseases (BMJ Journals) The Netherlands, 09 March 2016
Rheumatology
Key words: Sjogren's syndrome, b cells, parotide glands, rituximab [more]
Organism: Human
Tissue: Salivary Gland
Pathological State: Sjögren's Syndrome
Acquisition of chemoresistance and other malignancy-related features of colorectal cancer cells are incremented by ribosome-inactivating stress
Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) South Korea, 09 March 2016
Oncology
Key words: Ribosome-inactivating stress (RIS), Colorectal cancer, Activating transcription factor 3 (ATF3), Macrophage inhibitory cytokine-1 (MIC-1), Chemosensitivity [more]
Organism: Mouse
Tissue: Allograft Tumor, Colon
Pathological State: Cancer
Exploring the role of sphingolipid machinery during the epithelial to mesenchymal transition program using an integrative approach
Oncotarget (Impact Journals) Austria, Switzerland, 07 March 2016
Oncology
Key words: sphingolipid-related targets, sphingosine 1-phosphate/ceramide rheostat, multigene signature, epithelial to mesenchymal transition, lung cancer [more]
Organism: Human
Pathological State: Cancer
Cell Line: Lung adenocarcinoma epithelial cell line A549
Intrathecal transplantation of embryonic stem cell-derived spinal GABAergic neural precursor cells attenuates neuropathic pain in a spinal cord injury rat model
Cell Transplantation (SAGE Journals) South Korea, 01 March 2016
Regenerative Medicine
Key words: Spinal cord injury (SCI), Neuropathic pain, Spinal GABAergic neurons, Intrathecal transplantation [more]
Organism: Rat
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Platelet-rich plasma influences expansion and paracrine function of adipose-derived stromal cells in a dose-dependent fashion
Plastic and Reconstructive Surgery (Ingentaconnect) The Netherlands, 01 March 2016
Regenerative Medicine
Organism: Human
Tissue: Adipose Tissue
Double Linear Gradient Biointerfaces for Determining Two-Parameter Dependent Stem Cell Behavior
ChemNanoMat (Wiley) The Netherlands, 26 February 2016
Biological Methods
Key words: Biointerfaces, gradients, stem cell, wettability, stiffness [more]
Organism: Human
Cell Line: Mesenchymal stem cells from human bone marrow (hBM-MSCs)
Fenretinide: a potential treatment for endometriosis
Reproductive Sciences (SAGE Journals) USA, 25 February 2016
Reproductive Medicine
Key words: endometriosis, fenretinide, apoptosis, retinol, retinoid, STRA6, retinoic acid [more]
Organism: Mouse
Tissue: Endometrium
Pathological State: Endometriosis
Cooperation of ETV6/RUNX1 and BCL2 enhances immunoglobulin production and accelerates glomerulonephritis in transgenic mice
Oncotarget (Impact Journals) Austria, 23 February 2016
Oncology
Key words: ETV6/RUNX1, BCL2, glomerulonephritis, lymphoma, autoimmunity, Immunology and Microbiology Section, Immune response, Immunity [more]
Organism: Mouse
Tissue: Kidney
In situ analysis of intrahepatic virological events in chronic hepatitis B virus infection
The Journal of Clinical Investigation (American Society for Clinical Investigation) China, 22 February 2016
Virology
Key words: intrahepatic virological events, chronic hepatitis B virus infection [more]
Organism: Human
Tissue: Liver
Pathological State: Virus Infection
In EXOG-depleted cardiomyocytes cell death is marked by a decreased mitochondrial reserve capacity of the electron transport chain
Inside the Cell (Wiley) The Netherlands, 18 February 2016
Cell Biology
Key words: Cardiomyocyte, cell death, EXOG, hypertrophy, mitochondria [more]
Organism: Rat
Cell Line: NRVC cells ( neonatal rat ventricular cardiomyocytes )
Fc receptor-mediated phagocytosis in tissues as a potent mechanism for preventive and therapeutic HIV vaccine strategies
Mucosal Immunology (Nature) USA, Belgium, Germany, 17 February 2016
Key words: Cell signalling, HIV infections, Phagocytosis, Vaccines
Aging has small effects on initial ischemic acute kidney injury development despite changing intrarenal immunologic micromilieu in mice
American Journal of Physiology (APS Journals) South Korea, 15 February 2016
Physiology
Key words: Aging, ischemic, kidney injury, immunologic, micromilieu [more]
Organism: Mouse
Tissue: Kidney
Pathological State: Kidney Injury
The in vitro response of tissue stem cells to irradiation with different LETs
International Journal of Radiation Oncology (Elsevier) The Netherlands, 12 February 2016
Oncology
Key words: In vitro, tissue stem cells, irradiantion, LETs [more]
Organism: Human
Cell Line: HSG cells (human salivary gland cells)
Far-infrared promotes burn wound healing by suppressing NLRP3 inflammasome caused by enhanced autophagy
Journal of Molecular Medicine (Springer) Taiwan, 11 February 2016
Regenerative Medicine
Key words: Far-infrared, burn wound healing, autophagy NLRP3 inflammasome [more]
Organism: Rat
Tissue: Skin
Pathological State: Burn Wound
Serum Autoantibodies in Chronic Prostate Inflammation in Prostate Cancer Patients
PLoS One (PLOS) Austria, 10 February 2016
Oncology
Key words: Prostate cancer, autoantibodies, inflammation, prostate gland, inflammatory diseases, microarrays, prostate diseases, radical prostatectomy [more]
Organism: Human
Tissue: Prostate
Pathological State: Cancer
Acquisition of tumorigenic potential and enhancement of angiogenesis in pulmonary stem/progenitor cells through Oct-4 hyperexpression
Oncotarget (Impact Journals) Taiwan, 09 February 2016
Oncology
Key words: pulmonary stem/progenitor cells, cancer initiating cells, Oct-4, angiogenesis, angiopoietins/Tie2 [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
MINI ORAL SESSIONS (MINI38.12 Multiplex Immunofluorescence Identifies Differences in Immune Microenvironment and Prognostic Biomarkers between Mesothelioma Subtypes)
Journal of Thoracic Oncology (Elsevier) USA, 05 February 2016
Oncology
Key words: Multiplex immunofluorescence, immmune microenvironment, biomarkers, mesothelioma [more]
Organism: Human
Pathological State: Cancer
Oxytocin promotes functional coupling between paraventricular nucleus and both sympathetic and parasympathetic cardioregulatory nuclei
Hormones and Behavior (Elsevier) USA, 04 February 2016
Endocrinology
Key words: Oxytocin, functional coupling, paraventricular nucleus, cardioregulatory nuclei [more]
Organism: Mouse
Tissue: Brain
Prevention of SHIV transmission by topical IFN-β treatment
Mucosal Immunology (Nature) USA, 03 February 2016
Virology
Key words: Drug therapy, HIV infections, Mucosal immunology, Viral transmission [more]
Organism: Monkey
Tissue: Uterus
Pathological State: Virus Infection
Characterizing Villitis of Unknown Etiology and Inflammation in Stillbirth
The American Journal of Pathology (Elsevier) UK, 03 February 2016
Reproductive Medicine
Key words: Villitis, inflammation, stillbirth [more]
Organism: Human
Tissue: Placenta
Pathological State: Villitis
Treatment Regimen, Surgical Outcome, and T-cell Differentiation Influence Prognostic Benefit of Tumor-Infiltrating Lymphocytes in High-Grade Serous Ovarian Cancer
Clinical Cancer Research (High Wire) The Netherlands, 01 February 2016
Oncology
Key words: T-cell diferentiation, tumor-infiltrating lymphocytes, serous ovarian cancer [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
Infiltration of lymphocyte subpopulations into cancer microtissues as a tool for the exploration of immunomodulatory agents and biomarkers
Immunobiology (Elsevier) Austria, Switzerland, 01 February 2016
Immunology
Key words: 3D, biomarker, co-culture, cancer, immune cells, infiltration, subpopulation [more]
Organism: Human
Pathological State: Cancer
Cell Line: A549, Colo699, Calu-6 cells (human non-small-cell lung cancer cell lines)
FGF2 inhibits endothelial–mesenchymal transition through microRNA-20a-mediated repression of canonical TGF-ß signaling
Journal of Cell Science (The Company of Biologists) The Netherlands, 01 February 2016
Cell Biology
Key words: Endothelial–mesenchymal transition, microRNA-20a-mediated repression, canonical TGF-β signaling [more]
Organism: Human
Cell Line: HUVECs (Human umbilical vein endothelial cells)
Injectable extracellular matrix hydrogels as scaffolds for spinal cord injury repair
Tissue Engineering Part A (Mary Ann Liebert Inc.) Czech Republic, Norway, UK, Sweden, USA, 28 January 2016
Regenerative Medicine
Key words: spinal cord injury, hydrogel, extracellular matrix, scaffold, tissue engineering, stem cells [more]
Organism: Rat
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Amelioration of Experimental Autoimmune Arthritis Through Targeting of Synovial Fibroblasts by Intraarticular Delivery of MicroRNAs 140-3p and 140-5p
Arthritis & Rheumatology (Wiley) Taiwan, 25 January 2016
Rheumatology
Key words: Autoimmune arthritis, synovial fibroblasts, MicroRNAs [more]
Organism: Mouse
Tissue: Bone, Connective Tissue
Pathological State: Rheumatoid Arthritis
Novel technologies and emerging biomarkers for personalized cancer immunotherapy
Journal for ImmunoTherapy of Cancer (Springer) Qatar, USA, Switzerland, Greece, Germany, The Netherlands, Italy, Austria, 19 January 2016
Oncology
Key words: Immune checkpoint blockade, Cancer immunotherapy, Biomarkers, Task Force, Immune monitoring, Technology, Bioinformatics [more]
Organism: Human
Pathological State: Cancer
Fumaric acid esters promote neuronal survival upon ischemic stress through activation of the Nrf2 but not HIF-1 signaling pathway
Neuropharmacology (Elsevier) Germany, 19 January 2016
Neuroscience
Key words: Dimethyl fumarate, monomethyl fumarate, fumaric acid esters, Nrf2, HIF, ischemia [more]
Organism: Mouse
Tissue: Brain
Energy landscapes and functions of supramolecular systems
Nature Materials (Nature) USA, 18 January 2016
Biological Materials
Key words: Bioinspired materials, Materials science [more]
Organism: Mouse
Cell Line: C2C12 Mouse pre-myoblasts
Software-assisted morphometric and phenotype analyses of human peripheral blood monocyte-derived macrophages induced by a microenvironment model of human esophageal squamous cell carcinoma
Pathology International (Wiley) Japan, 18 January 2016
Pathology
Key words: Esophageal cancer, image analysis, macrophages, tumor microenvironment [more]
Organism: Human
Cell Line: PBMCs (Peripheral blood mononuclear cells )
Towards personalised treatment in primary Sjögren's syndrome: baseline parotid histopathology predicts responsiveness to rituximab treatment
Annals of the Rheumatic Diseases (High Wire) The Netherlands, Germany, 15 January 2016
Rheumatology
Key words: Sjögren's syndrome, parotid histopathology, responsiveness to rituximab treatment [more]
Organism: Human
Pathological State: Sjögren's Syndrome
Low birth weight associates with hippocampal gene expression
Neuroscience (Elsevier) Singapore, Canada, 12 January 2016
Neuroscience
Key words: Low birth weight, hippocampus, DNA methylation, mental disorders, microarray [more]
Organism: Monkey
Tissue: Brain
Inhibition of Aerobic Glycolysis Attenuates Disease Progression in Polycystic Kidney Disease
PLoS One (PLOS) Switzerland, 11 January 2016
Nephrology
Key words: Kidneys, glycolysis, renal system, epithelial cells, glucose metabolism, apoptosis, ERK signaling cascade, polycystic kidney disease [more]
Organism: Rat
Tissue: Kidney
Pathological State: Polycystic Kidney Disease
Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer
Genes and Development (CHS Press) USA, Switzerland, 10 January 2016
Oncology
Key words: Cathepsin protease, compensatory mechanism, cancer [more]
Organism: Mouse
Tissue: Pancreas
Pathological State: Cancer
Toll-Like Receptor 4 Is Essential in the Development of Abdominal Aortic Aneurysm
PLoS One (PLOS) Taiwan, 07 January 2016
Immunology
Key words: Macrophages, immune receptor signaling, aneurysms, inflammation, toll-like receptors, aorta, small interfering RNAs, cytokines [more]
Organism: Mouse
Tissue: Kidney
The single-chain anti-TNF-a antibody DLX105 induces clinical and biomarker responses upon local administration in patients with chronic plaque-type psoriasis
Experimental Dermatology (Wiley) Germany, Austria, Switzerland, 06 January 2016
Dermatology
Key words: Psoriasis, TNF-alpha, TNF-alpha-blocker [more]
Organism: Human
Tissue: Skin
Pathological State: Psoriasis
3, 4-Dihydroxy-L-phenylalanine as a novel covalent linker of extracellular matrix proteins to polyacrylamide hydrogels with a tunable stiffness
Tissue Engineering Part C (Mary Ann Liebert Inc.) The Netherlands, 05 January 2016
Regenerative Medicine
Key words: Tissue Enigneering, 3,4-Dihydroxy-L-Phenylalanine, Linker, Extracellular Matrix, Hydrogel, Stiffness [more]
Organism: Human
Cell Line: Human dermal fetal fibroblasts
T1 Mapping by CMR Imaging : From Histological Validation to Clinical Implication
JACC: Cardiovascular Imaging (Elsevier) Austria, Germany, 01 January 2016
Cardiology
Key words: CMR imaging, histological validation [more]
Organism: Human
Tissue: Heart
N-octanoyl dopamine attenuates the development of transplant vasculopathy in rat aortic allografts via smooth muscle cell protective mechanisms
Transplantation (Wolters Kluwer) The Netherlands, Germany, 01 January 2016
Transplantation Medicine
Key words: N-octanoyl Dopamine, Transplant Vasculopathy, Aortic Allografts, Smooth Muscle Cells, Protective Mechanisms [more]
Organism: Rat
Tissue: Blood Vessels
The anti-inflammatory compound curcumin enhances locomotor and sensory recovery after spinal cord injury in rats by immunomodulation
International Journal of Molecular Sciences (MDPI) Czech Republic, USA, 31 December 2015
Neuroscience
Key words: spinal cord injury, curcumin, inflammation, cytokines, secondary processes, NF-κB [more]
Organism: Rat
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Mercury toxicokinetics of the healthy human term placenta involve amino acid transporters and ABC transporters
Toxicology (Elsevier) Austria, 29 December 2015
Toxicology
Key words: Mercury, placenta, amino acid transporters [more]
Organism: Human
Tissue: Placenta
Long-term in vitro expansion of salivary gland stem cells driven by Wnt signals
Stem Cell Reports (Elsevier) The Netherlands, 24 December 2015
Stem Cell Research
Key words: In Vitro Expansion, Salivary Gland, Stem Cells, Wnt [more]
Organism: Mouse
Tissue: Salivary Gland
Long-Term In Vitro Expansion of Salivary Gland Stem Cells Driven by Wnt Signals
Stem Cell Reports (Elsevier) The Netherlands, 24 December 2015
Stem Cell Research
Key words: Stem cells, in vitro expansion, wnt signals [more]
Organism: Human
Tissue: Salivary Gland
Co-culture of placental explants with isolated CD4 and CD8 T cells: a functional model to define the consequences of placental inflammation
Journal of Biological Methods (Springer) UK, 22 December 2015
Reproductive Medicine
Key words: inflammation, placenta, T lymphocytes, villitis, VUE [more]
Organism: Human
Cell Line: Placental T-cells
Mycolic acid-specific T cells protect against Mycobacterium tuberculosis infection in a humanized transgenic mouse model
eLife (eLife Sciences Publications) USA, 10 December 2015
Microbiology
Key words: Mycolic acid-specific T cells, Mycobacterium tuberculosis, humanized transgenic mouse model [more]
Organism: Mouse
Tissue: Lung
Pathological State: Bacterial Infection
Reproductive periodicity, spawning induction, and larval metamorphosis of the hemichordate acorn worm Ptychodera flava
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution (Wiley) Taiwan, 10 December 2015
Zoology
Key words: Reproductive periodicity, larval metamorphosis, hemichordate [more]
Organism: Acorn worm
Tissue: Penis
Low Hodgkin/Reed-Sternberg Cell Density Assessed with Automated Image Analysis Is a Poor Prognostic Factor in Classic Hodgkin Lymphoma Patients
Blood (American Society of Hematology) Czech Republic, 03 December 2015
Oncology
Key words: Cell Density, Automated Image Analysis, Prognostic Factor, Hodgkin Lymphoma [more]
Organism: Human
Tissue: Lymphoid Tissue
Pathological State: Cancer
Quantitative Analysis of Tissue Inflammation and Responses to Treatment in Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked (IPEX) Syndrome and Review of Literature
Journal of Microbiology, Immunology and Infection (Elsevier) Taiwan, USA, 01 December 2015
Immunology, Microbiology
Key words: Immune dysregulation, polyendocrinopathy, enteropathy, X-Linked (IPEX) syndrome, regulatory T cells, T helper 2 cells [more]
Organism: Human
Tissue: Small Intestine
Pathological State: Endocrinopathy, Enteropathy, X-linked syndrome
Hirsutella sinensis mycelium attenuates bleomycin-induced pulmonary inflammation and fibrosis in vivo
J Cancer Treat Diagnosis (Nature) Taiwan, USA, 26 November 2015
Microbiology
Key words: Drug development, Inflammasome [more]
Organism: Human
Tissue: Lung
Pathological State: Inflammation, Fibrosis
Dynamic Trk and G Protein Signalings Regulate Dopaminergic Neurodifferentiation in Human Trophoblast Stem Cells
PLoS One (PLOS) Taiwan, USA, 25 November 2015
Neuroscience
Key words: Neurons, DNA transcription, G-protein signaling, stem cells, genomic signal processing, retinoic acid signaling cascade, retinoid signaling, neuronal differentiation [more]
Organism: Human
Cell Line: hTS cells
Curcumin Suppresses Phthalate-Induced Metastasis and the Proportion of Cancer Stem Cell (CSC)-like Cells via the Inhibition of AhR/ERK/SK1 Signaling in Hepatocellular Carcinoma
Journal of Agricultural Food Chemistry (ACS Publications) Taiwan, 20 November 2015
Oncology
Key words: Phthalate, curcumin, hepatocellular carcinoma, metastasis, side population, cancer stem cells [more]
Organism: Mouse
Tissue: Liver, Lung
Alpha-Actinin 4 Is Associated with Cancer Cell Motility and Is a Potential Biomarker in Non–Small Cell Lung Cancer
Journal of Thoracic Oncology (Elsevier) Taiwan, 20 November 2015
Oncology
Key words: ACTN4, non–small-cell lung cancers, CL1-0 and CL1-5 cell lines, siRNA [more]
Organism: Human
Tissue: Lung
Pathological State: Cancer
MiR-125b is critical for fibroblast-to-myofibroblast transition and cardiac fibrosis
Circulation (AHA Journals) USA, 19 November 2015
Cardiology
Key words: RNA sequence, fibrosis, angiotensin II, transforming growth factor, miR-125b [more]
Organism: Mouse
Tissue: Heart
Pathological State: Fibrosis
CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow
Journal of Experimental Medicine (Rockefeller University Press) Japan, 09 November 2015
Stem Cell Research
Key words: CLEC-2, megakaryocyte, hematopoietic stem cells, bone marrow [more]
Organism: Mouse
Tissue: Bone Marrow
IMPS-11 Expression and prognostic impact of immune modulatory molecule PD-L1 in meningioma
Neuro-Oncology (Oxford University Press) USA, 09 November 2015
Oncology
Key words: meningioma, patient prognosis, impact, molecule, programmed cell death 1 ligand 1 [more]
Organism: Human
Tissue: Brain
Pathological State: Cancer
Transdermal drug targeting and functional imaging of tumor blood vessels in the mouse auricle
The FASEB Journal (FASEB) Germany, 06 November 2015
Oncology
Key words: angiogenesis • blood vessel growth • bortezomib • mouse model • perfusion [more]
Organism: Mouse
Pathological State: Cancer
Melanin pigmentation in rat eyes: in vivo imaging by polarization-sensitive optical coherence tomography and comparison to histology
Investigative Ophthalmology and Visual Science (ARVO Journals) Austria, 01 November 2015
Ophthalmology
Key words: Melanin Pigmentation, Eyes, In Vivo Imaging, Polarization-Sensitive Optical Coherence Tomography [more]
Organism: Rat
Tissue: Eye
Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-a Production in Women
Journal of Immunology (American Association of Immunologists) France, Germany, UK, Australia, 30 October 2015
Immunology
Key words: Plasmacytoid dendridic cell levels, IRF5 [more]
Organism: Human, Mouse
Cell Line: PBMCs (Peripheral blood mononuclear cells )
Astrocytic CCAAT/Enhancer-Binding Protein Delta Contributes to Glial Scar Formation and Impairs Functional Recovery After Spinal Cord Injury
Molecular Neurobiology (Springer) Taiwan, 28 October 2015
Neuroscience
Key words: Astrogliosis C/EBPd, MMP-3 RhoA, astrocyte migration [more]
Organism: Mouse
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Novel p53-dependent anticancer strategy by targeting iron signaling and BNIP3L-induced mitophagy
Oncotarget (Impact Journals) Austria, 26 October 2015
Oncology
Key words: cancer, p53, BNIP3L, mitophagy, gallium complex [more]
Organism: Human
Pathological State: Cancer
Cell Line: Human colon carcinoma cells
Quantitative Image Analysis of Epithelial and Stromal Area in Histological Sections of Colorectal Cancer: An Emerging Diagnostic Tool.
Biomed Research International (Hindawi Publishing Corporation) Austria, Romania, 22 October 2015
Oncology
Key words: Image analysis, histology, colorectal cancer, diagnosis tool [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Glucose-regulated protein 94 mediates cancer progression via AKT and eNOS in hepatocellular carcinoma
Tumor Biology (Springer) Taiwan, Mongolia, 22 October 2015
Oncology
Key words: GRP94 HCC eNOS AKT Proliferation [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Redox Regulation of Pro-IL-1β Processing May Contribute to the Increased Severity of Serum-Induced Arthritis in NOX2-Deficient Mice
Antioxidants and Redox Signaling (Mary Ann Liebert Inc.) Taiwan, USA, 21 October 2015
Rheumatology
Key words: Redox Regulation,Pro-IL-1β,Serum-Induced Arthritis, NOX2 [more]
Organism: Mouse
Tissue: Bone, Connective Tissue
Pathological State: Rheumatoid Arthritis
An Emerging Approach for Parallel Quantification of Intracellular Protozoan Parasites and Host Cell Characterization Using TissueFAXS Cytometry
PLoS One (PLOS) Germany, Austria, 21 October 2015
Parasitology
Key words: Macrophages, parasitic diseases, host cells, leishmania major, DAPI staining, cell staining, host-pathogen interactions, intracellular pathogens [more]
Organism: Mouse
Pathological State: Parasitic Infection
Cell Line: Makrophages
The Role of Lysophosphatidic Acid on Airway Epithelial Cell Denudation in a Murine Heterotopic Tracheal Transplant Model
Transplantation (Wolters Kluwer) Japan, 19 October 2015
Transplantation Medicine
Key words: Lysophosphatidic Acid, Airway Epithelial Cells, Denudation, Murine Heterotopic Tracheal Transplant Model [more]
Organism: Mouse
Cell Line: BEAS-2B cells
Development of recombinant collagen-peptide-based vehicles for delivery of adipose-derived stromal cells (ADSC)
Journal of Biomedical Materials Research (Wiley) The Netherlands, 14 October 2015
Biological Materials
Key words: Recombinant-Collagen Microspheres, integrin binding motives, crosslinked, ADSC, delivery [more]
Organism: Human
Cell Line: Adipose tissue derived stromal cells (ADSC)
Cardioprotective Actions of TGFßRI Inhibition Through Stimulating Autocrine/Paracrine of Survivin and Inhibiting Wnt in Cardiac Progenitors
Stem Cells (Wiley) Taiwan, USA, 10 October 2015
Stem Cell Research
Key words: Nkx2.5, sca1, Birc5, survivin, MEK/ERK, Wnt3a [more]
Organism: Mouse
Tissue: Heart
Pathological State: Fibrosis
YAP1 Is a Driver of Myofibroblast Differentiation in Normal and Diseased Fibroblasts
The American Journal of Pathology (Elsevier) The Netherlands, Canada, 10 October 2015
Pathology
Key words: Myofibroblast, fibroblasts, YAP 1 [more]
Organism: Human
Pathological State: Dupuytren's Disease
Cell Line: Dermal fibroblasts
The pro-fibrotic properties of transforming growth factor on human fibroblasts are counteracted by caffeic acid by inhibiting myofibroblast formation and collagen synthesis
Cell and Tissue Research (Springer) The Netherlands, 09 October 2015
Cell Biology
Key words: Fibrosis, collagen, myofibroblasts, caffeic acid, lysyl hydroxylase [more]
Organism: Human
Cell Line: HDFa and HLFa Fibroblasts