Customer Publications (A total of 3040 papers published)
In vivo real-time fluorescence visualization and brain-targeting mechanisms of lipid nanocarriers with different fatty ester:oil ratios
Future Medicine (FSG) Taiwan, Saudi Arabia, 27 March 2014
Nanomedicine
Key words: Lipid nanocarriers, cetyl palmitate, squalene, sulforhodamine B [more]
Organism: Rat
Tissue: Brain
RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis
The Journal of Clinical Investigation (American Society for Clinical Investigation) France, The Netherlands, UK, 25 March 2014
Oncology
Organism: Human
Tissue: Colon
Pathological State: Cancer
Ambivalent role of pFAK-Y397 in serous ovarian cancer-a study of the OVCAD consortium
Molecular Cancer (Springer) Austria, Germany, Belgium, 21 March 2014
Oncology
Key words: FAK, pFAK, molecular subclassification, immunohistochemistry, prognosis, ovarian cancer [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
Protection against Dengue Virus Infection in Mice by Administration of Antibodies against Modified Nonstructural Protein 1
PLoS One (PLOS) Taiwan, Canada, 21 March 2014
Virology
Key words: Hemorrhage, endothelial cells, platelets, complement system, dengue fever, hematoxylin staining, inoculation, macrophages [more]
Organism: Mouse
Tissue: Skin
Pathological State: Dengue Virus Infection
Lamin B2 prevents chromosome instability by ensuring proper mitotic chromosome segregation
Oncogenesis (Nature) Japan, 17 March 2014
Oncology
Key words: Chromosome segregation, Colorectal cancer, Mitotic spindle [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Hedgehog Pathway Inhibition in Chondrosarcoma Using the Smoothened Inhibitor IPI-926 Directly Inhibits Sarcoma Cell Growth
Molecular Cancer Therapeutics (AACR Publications) USA, Canada, 14 March 2014
Oncology
Key words: Hedgehog (Hh) pathway, Chondrosarcoma, transmembrane receptor Patched [more]
Organism: Mouse
Tissue: Xenograft Tumor, Joint Tissue
Pathological State: Cancer
Blockade of Fas Signaling in Breast Cancer Cells Suppresses Tumor Growth and Metastasis via Disruption of Fas Signaling-initiated Cancer-related Inflammation
Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) China, 13 March 2014
Oncology
Key words: Breast Cancer, fas inflammation, prostaglandins, tumor metastases IL-6 MDSC PGE2 [more]
Organism: Mouse
Tissue: Breast
Pathological State: Cancer
Interleukin-1β Attenuates Myofibroblast Formation and Extracellular Matrix Production in Dermal and Lung Fibroblasts Exposed to Transforming Growth Factor-β1
PLoS One (PLOS) The Netherlands, 12 March 2014
Cell Biology
Key words: Fibroblasts, collagens, gene expression, fibrosis, immunofluorescence staining, tissue repair, cytokines, lungs [more]
Organism: Human
Cell Line: HDFa and HLFa cells
5th International meeting on angiogenesis
Angiogenesis (Springer) The Netherlands, 08 March 2014
Regenerative Medicine
Impact of the Smoothened Inhibitor, IPI-926, on Smoothened Ciliary Localization and Hedgehog Pathway Activity
PLoS One (PLOS) USA, 07 March 2014
Oncology
Key words: Hedgehog signaling NIH 3T3 cells, cancer treatment, cell binding assay, cilia, gene expression, luciferase, cell staining [more]
Organism: Human
Cell Line: HEPM and NIH-3T3 cells
Excessive activation of the alternative complement pathway in autosomal dominant polycystic kidney disease
Journal of Internal Medicine (Wiley) China, Switzerland, USA, 02 March 2014
Nephrology
Key words: Autosomal dominant polycystic kidney disease, complement, complement inhibitor, glycoproteomics, urine [more]
Organism: Rat
Tissue: Kidney
Pathological State: Kidney Disease
AB0206 Altered Expression of Angiopoietins and Tie-2 in Ischemic Lesions of UCD-206 Chickens, an Animal Model for Systemic Sclerosis
Annals of the Rheumatic Diseases (BMJ Journals) Austria, 01 March 2014
Rheumatology
Key words: Systemic sclerosis, vascular endothelial growth factor, endothelial cells
Multimodality imaging to assess immediate response to irreversible electroporation in a rat liver tumor model
Radiology (Radiological Society of North America) USA, 18 February 2014
Oncology
Organism: Rat
Tissue: Liver
Pathological State: Cancer
Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma
Cancer (Wiley) Canada, USA, 15 February 2014
Oncology
Key words: Osteosarcoma, hedgehog signaling, ligand-dependent, IPI-926, microenvironment [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Iron deficiency alters megakaryopoiesis and platelet phenotype independent of thrombopoietin
American Journal of Hematology (Wiley) Austria, Germany, 14 February 2014
Hematology
Key words: Iron deficiency [more]
Organism: Rat
Tissue: Bone Marrow
NKG2D+ IFN-γ+ CD8+ T Cells Are Responsible for Palladium Allergy
PLoS One (PLOS) Japan, 12 February 2014
Allergy Research
Key words: T cells, cytotoxic T cells, allergies, mouse models, adoptive transfer, lymphocytes, allergy immunotherapy, lymph nodes [more]
Organism: Mouse
Tissue: Lymphoid Tissue
Pathological State: Allergy
Successful treatment of adult onset Langerhans cell histiocytosis with bi-weekly administration of pegylated interferon-α
Acta Dermato Venereologica (Ingentaconnect) Japan, 04 February 2014
Dermatology
Organism: Human
Tissue: Skin
Pathological State: Histiocytosis
Serum Level of IL-10 Is Increased in Patients with Endometriosis, and IL-10 Promotes the Growth of Lesions in a Murine Model
The American Journal of Pathology (American Society for Investigative Pathology) Taiwan, 01 February 2014
Pathology
Key words: Immune dysregulation, anti-inflammatory cytokine IL-10, Monocyte-derived dendritic cells [more]
Organism: Mouse
Tissue: Uterus
Pathological State: Endometriosis
Metformin anti-tumor effect via disruption of the MID1 translational regulator complex and AR downregulation in prostate cancer cells
BMC Cancer (Springer) Austria, Germany, 31 January 2014
Oncology
Key words: Metformin, Androgen receptor, MID1-α4/PP2A protein complex, AMPK, Translational regulation, CoIP [more]
Organism: Human
Cell Line: LNCaP, Du-145, VCaP and PC-3 cells
Role of oncogenic K-Ras in cancer stem cell activation by aberrant Wnt/β-catenin signaling
Journal of the National Cancer Institute (Oxford University Press) South Korea, 31 January 2014
Oncology
Key words: signal transduction, mutation, cd44 antigens, transplantation, heterologous, mice, neoplasms, k-ras oncogene, homing-associated cell adhesion molecule, cancer stem cells [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Die prognostische Bedeutung von Tumor-infiltrierenden CD8+Zellen: eine detaillierte Analyse in Hinblick auf Tumor-Debulking und Zell-Proliferation
Geburtshilfe und Frauenheilkunde (Thieme) Austria, 30 January 2014
Immunology
The role of the organic anion transporting polypeptide OATP4A1 in immunactivation in colorectal cancer and inflammatory colon disease.
Journal of Clinical Oncology (American Society of Clinical Oncology) , 20 January 2014
Oncology
Key words: Prostaglandins, cyclic nucleotides, second messenger proteins, tumor cells growth
A dual role for autophagy in a murine model of lung cancer
Nature Communications (Nature) Austria, France, 20 January 2014
Oncology
Key words: Autophagy, Lung cancer, Oncogenesis [more]
Organism: Mouse
Tissue: Lung
Pathological State: Cancer
Glycogen Synthase Kinase 3β (GSK3β) Regulates Differentiation and Proliferation in Neural Stem Cells from the Rat Subventricular Zone 1
Journal of Proteome Research (ACS Publications) Germany, 18 January 2014
Stem Cell Research
Key words: Neural stem cell, Neurosphere, Glycogen Synthase Kinase 3β, Two-dimensional gel electrophoresis, Rat, Subventricular zone [more]
Organism: Rat
Tissue: Brain
NF-E2-related factor 2 promotes compensatory liver hypertrophy after portal vein branch ligation in mice
Hepatology (Wiley) Japan, 17 January 2014
Hepatology
Key words: Hepatectomy, portal vein embolization, phosphoinositide 3-kinase, protein kinase B (PI3K/Akt) pathway [more]
Organism: Mouse
Tissue: Liver
Hepatic RIG-I Predicts Survival and Interferon-α Therapeutic Response in Hepatocellular Carcinoma
Cancer Cell (Cell Press) China, 13 January 2014
Oncology
Key words: Hepatocellular carcinoma, interferon-α, retinoic acid-inducible gene-I [more]
Organism: Human
Tissue: Liver
Pathological State: Cancer
Diverse T-cell responses characterize the different manifestations of cutaneous graft-versus-host disease
Blood (American Society of Hematology) Austria, 09 January 2014
Transplantation Medicine
Key words: Distinct T-cell patterns characterize the acute and chronic forms of cutaneous GVHD, increased TSLP expression is an indicator of acute cutaneous GVHD development. [more]
Organism: Human
Tissue: Skin
Pathological State: Graft-versus-host disease
Resveratrol enhances the chemopreventive effect of celecoxib in chemically induced breast cancer in rats
European Journal of Cancer Prevention (Wolters Kluwer) Austria, 01 January 2014
Oncology
Key words: celecoxib, chemically induced breast cancer, COX2, GDF15, MCF-7 cells, oxidative stress, resveratrol [more]
Organism: Rat
Tissue: Breast
Pathological State: Cancer
Macrophage Quantification in Different Breast Tumor Compartments.
Jurnalul de Chirurgie (search.ebscohost.com) Romania, 01 January 2014
Oncology
Lymph node status assessed through the log odds ratio–a better tool in the prognosis of colorectal cancer relapse
Romanian Journal of Morphology and Embryology () Romania, 01 January 2014
Oncology
Key words: disease-free interval, lymph node ratio, log odds ratio.
HISTOQUEST–MODALITY OF MICROANATOMICAL ANALYSIS OF THE IMMUNOHISTOCHEMICAL COLORATION IN BREAST CANCER AND DATA …
Romanian Journal of Functional & Clinical, Macro- & Microscopical Anatomy & of Anthropology (EBSCO) Romania, 01 January 2014
Oncology
Role of endocytic uptake in transfection efficiency of solid lipid nanoparticles-based nonviral vectors
Journal of Gene Medicine (Wiley) Spain, Austria, 27 December 2013
Nanomedicine
Key words: Endocytosis, lysosome, nonviral vector, solid lipid nanoparticles, transfection [more]
Organism: Human
Cell Line: HeLa cells
Ginsenoside Rg3 Up-regulates the Expression of Vascular Endothelial Growth Factor in Human Dermal Papilla Cells and Mouse Hair Follicles
Phytotherapy Research (Wiley) South Korea, 26 December 2013
Dermatology
Key words: Rg3, hair growth, DP cell, gene expression profiles, VEGF, stemness marker [more]
Organism: Human
Cell Line: Dermal Papilla cells
Application of quinidine on rat sciatic nerve decreases the amplitude and increases the latency of evoked responses
Journal of Anesthesia (Springer) Taiwan, 15 December 2013
Anesthesiology
Key words: Sciatic nerve, lidocaine, sciatic nerve fiber, contralateral hind limb, rat sciatic nerve, quinidine concentration, sodium channel, ranvier node, myelinated nerve fiber, local anesthetic, nerve conduction, peripheral nerve, neuropathic pain, conduction velocity [more]
Organism: Rat
Tissue: Brain
Autophagy suppresses tumorigenesis of hepatitis B virus-associated hepatocellular carcinoma through degradation of microRNA-224
Hepatology (Wiley) Taiwan, 13 December 2013
Oncology
Key words: microRNA-224, miR‐224 antagonist, autophagosome fraction, autophagy‐related genes, chloroquine, double distilled water, digoxigenin, hepatitis B virus, hepatitis B virus X protein, hepatocellular carcinoma, hepatitis C virus [more]
Organism: Human
Tissue: Liver
Pathological State: Cancer
Overexpression of FGF9 in colon cancer cells is mediated by hypoxia-induced translational activation
Nucleic Acids Research (Oxford University Press) Taiwan, 10 December 2013
Oncology
Key words: Human fibroblast growth factor 9, hypoxia, colon cancer cells [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Localized Hyperthermia with Iron Oxide–Doped Yttrium Microparticles: Steps toward Image-Guided Thermoradiotherapy in Liver Cancer
Journal of Vascular and Interventional Radiology (Elsevier) USA, 06 December 2013
Oncology
Key words: Hepatocellular carcinoma, normal hepatic parenchyma, alternating magnetic field [more]
Organism: Rat
Tissue: Liver
Pathological State: Cancer
MAR-mediated integration of plasmid vectors for in vivo gene transfer and regulation
BMC Molecular Biology (Springer) Switzerland, Poland, 02 December 2013
Genetics
Key words: Inducible expression, non-viral vectors, MAR elements, erythropoietin, utrophin, gene therapy [more]
Organism: Mouse
Tissue: Muscle
Transdifferentiation of Adipose-Derived Stem Cells into Keratinocyte-Like Cells: Engineering a Stratified Epidermis
PLoS One (PLOS) USA, 02 December 2013
Stem Cell Research
Key words: Keratinocytes, cell staining, transdifferentiation, cell differentiation, mesenchymal stem cells, DAPI staining, antibiotics, fibroblasts [more]
Organism: Human
Cell Line: Adipose-Derived Stem Cells
Targeting SOD1 reduces experimental non–small-cell lung cancer
The Journal of Clinical Investigation (American Society for Clinical Investigation) USA, 02 December 2013
Oncology
Organism: Mouse
Tissue: Lung
Pathological State: Cancer
Langerhans cell maturation is accompanied by induction of N-cadherin and the transcriptional regulators of epithelial–mesenchymal transition ZEB1/2
European Journal of Immunology (Wiley) Austria, 02 December 2013
Immunology
Key words: Cell migration, dendritic cells, epithelial-to-mesenchymal transition, langerhans cells, maturation [more]
Organism: Human
Cell Line: Langerhans cells
A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog
Development (The Company of Biologists) Austria, Switzerland, UK, 19 November 2013
Neuroscience
Key words: Histone deacetylases, neural cells, histone acetyltransferases, central nervous system [more]
Organism: Mouse
Tissue: Brain
Developmental and oncogenic radiation effects on neural stem cells and their differentiating progeny in mouse cerebellum
Stem Cells (Wiley) Italy, 15 November 2013
Stem Cell Research
Key words: Ptc1+/- mice, apoptosis, DNA repair, p21, medulloblastoma, carcinogenesis, neural stem cells, progenitor cells [more]
Organism: Mouse
Tissue: Brain
Epidermal Growth Factor Receptor Targeted Nuclear Delivery and High-Resolution Whole Cell X-ray Imaging of Fe3O4@TiO2 Nanoparticles in Cancer Cells
ACS NANO (ACS Publications) USA, 12 November 2013
Bioimaging
Key words: Nanoparticles, titanium dioxide, photoactivation, X-ray fluorescence microscopy, epidermal growth factor receptor [more]
Organism: Human
Cell Line: HeLa cells
Cardiac magnetic resonance postcontrast T1 time is associated with outcome in patients with heart failure and preserved ejection fraction
Circulation:Cardiovascular Imaging (AHA Journals) Austria, Turkey, 06 November 2013
Cardiology
Key words: Hypertension, pulmonary, magnetic resonance imaging, prognosis [more]
Organism: Human
Tissue: Heart
Pathological State: Heart Failure
Hypercapnia Impairs Lung Neutrophil Function and Increases Mortality in Murine Pseudomonas Pneumonia
American Journal of Respiratory Cell and Molecular Biology (ATS Journals) USA, 01 November 2013
Pulmonology
Key words: arbon dioxide, pulmonary infection, reactive oxygen species, phagocytosis, inflammation [more]
Organism: Mouse
Tissue: Lung
Pathological State: Pseudomonas Infection, Pneumonia
Corelation of Lymphocytic Infiltrates with the Prognosis of Recurrent Colo-Rectal Cancer
Chirurgia (revistachirurgia) Romania, 01 November 2013
Oncology
Key words: relapse prognosis, colo-rectal cancer, quantitative assessment of immunohistochemical staining, digital image analysis, cytotoxic T cells [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Alcohol Exacerbates LPS-Induced Fibrosis in Subclinical Acute Pancreatitis
The American Journal of Pathology (Elsevier) Germany, 01 November 2013
Gastroenterology
Key words: Pancreatic acinar cells, alcoholic acute pancreatitis, growth factor-β of acinar cells, pancreatic fibrosis [more]
Organism: Rat
Tissue: Pancreas
Pathological State: Cancer
Renal Heparan Sulfate Proteoglycans Modulate Fibroblast Growth Factor 2 Signaling in Experimental Chronic Transplant Dysfunction
The American Journal of Pathology (Elsevier) The Netherlands, 01 November 2013
Transplantation Medicine
Key words: Renal transplantation, proteoglycans, chronic transplant dysfunction, laser-microdissected glomeruli [more]
Organism: Rat
Tissue: Kidney
Pathological State: Chronic Transplant Dysfunction, Organ Transplantation
Targeting of sodium–glucose cotransporters with phlorizin inhibits polycystic kidney disease progression in Han: SPRD rats
Kidney international (Elsevier) Switzerland, China, Germany, 01 November 2013
Nephrology
Key words: polycystic, phlorizin, rat, sodium–glucose cotransport [more]
Organism: Rat
Tissue: Kidney
Pathological State: Kidney Disease
AKIP1, a cardiac hypertrophy induced protein that stimulates cardiomyocyte growth via the Akt pathway
International Journal of Molecular Sciences (MDPI) The Netherlands, China, 28 October 2013
Cardiology
Key words: cardiac hypertrophy, AKIP1, Akt, kinase, remodeling [more]
Organism: Rat
Cell Line: Neonatal rat ventricular cardiomyocytes
Regulation of the calcium-sensing receptor expression by 1,25-dihydroxyvitamin D3, interleukin-6, and tumor necrosis factor alpha in colon cancer cells
The Journal of Steroid Biochemistry and Molecular Biology (Elsevier) Austria, 28 October 2013
Oncology
Key words: Calcium-sensing receptor, colon cancer, tumor necrosis factor alpha, interleukin, 1, 25-dihydroxyvitamin D3, Inflammation [more]
Organism: Human
Cell Line: Caco-2 Cells
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie
Oncology research and treatment (Karger) Austria, 22 October 2013
Oncology
Effects on tumor development and metastatic dissemination by the NKG2D lymphocyte receptor expressed on cancer cells
Oncogene (Nature) USA, 21 October 2013
Oncology
Key words: Breast cancer, Metastasis, Oncogene proteins, Oncogenesis [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation
Neurobiology of Disease (Elsevier) Italy, 16 October 2013
Neuroscience
Key words: Sigma-1 receptor, motor neurons, BDNF, reactive gliosis, neurodegeneration, obbler [more]
Organism: Mouse
Tissue: Spinal Cord
Pathological State: Motor Neuron Disease
Overexpression of the Transcriptional Repressor Complex BCL-6/BCoR Leads to Nuclear Aggregates Distinct from Classical Aggresomes
PLoS One (PLOS) Austria, 11 October 2013
Cell Biology
Key words: Transfection, chaperone proteins, heat shock response, plasmid construction, cell staining, immunostaining, nuclear bodies, protein structure [more]
Organism: Human
Cell Line: Primary Ecs
Suberoylanilide Hydroxamic Acid, an Inhibitor of Histone Deacetylase, Enhances Radiosensitivity and Suppresses Lung Metastasis in Breast Cancer In Vitro and In Vivo
PLoS One (PLOS) Taiwan, 10 October 2013
Oncology
Key words: Cancer treatment, autophagic cell death, breast cancer, DNA damage, apoptosis, metastasis, fluorescence microscopy, DNA repair [more]
Organism: Mouse
Tissue: Breast
Pathological State: Cancer
Necro-inflammatory response of pancreatic acinar cells in the pathogenesis of acute alcoholic pancreatitis
Cell Death & Disease (Nature) Germany, USA, 03 October 2013
Gastroenterology
Key words: Acute pancreatitis, Inflammation, Necroptosis [more]
Organism: Rat, Human
Tissue: Pancreas
Pathological State: Pancreatitis
Characterization of T Cell Receptors of Th1 Cells Infiltrating Inflamed Skin of a Novel Murine Model of Palladium-Induced Metal Allergy
PLoS One (PLOS) Japan, 03 October 2013
Allergy Research
Key words: T cells, allergies, T cell receptors, polymerase chain reaction, cytokines, inflammation, chemokines, sequence analysis [more]
Organism: Mouse
Comparison of Interleukin-17- Producing Cells in Different Clinical Types of Alopecia Areata
Dermatology (Karger) Japan, 01 October 2013
Dermatology
Key words: Alopecia areata Interleukin-17 Interferon Acute, diffuse and total alopecia [more]
Organism: Human
Tissue: Skin
Pathological State: Alopecia Areata
Expression Of CD8 Is Associated With Non-Common Type Morphology And Outcome In Pediatric Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma
Haematologica (Ferrata Storti Foundation) Germany, Russia, 01 October 2013
Oncology
Key words: Anaplastic lymphoma kinase, CD30-positive T-cell lymphoma, vinblastine, autologous, allogeneic hematopoietic stem cell transplantation [more]
Organism: Human
Tissue: Lymphoid Tissue
Pathological State: Cancer
Up-Regulation of SOX9 in Sertoli Cells from Testiculopathic Patients Accounts for Increasing Anti-Mullerian Hormone Expression via Impaired Androgen Receptor Signaling
PLoS One (PLOS) Taiwan, USA, 01 October 2013
Endocrinology
Key words: Sertoli cells, testes, androgens, spermatogenesis, reverse transcriptase-polymerase chain reaction, testosterone, adults, germ cells [more]
Organism: Human
Tissue: Testis
Pathological State: Sertoli-cell-only syndrome
Digital immunohistochemistry: new horizons and practical solutions in breast cancer pathology
Diagnostic Pathology (BioMed Central) Lithuania, 30 September 2013
Oncology
Key words: Breast cancer, Immunohistochemistry (IHC) biomarkers, tissue microarray [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
Loss of phosphatase and tensin homolog (PTEN) in myeloid cells controls inflammatory bone destruction by regulating the osteoclastogenic potential of myeloid cells
Annals of the Rheumatic Diseases (BMJ Journals) Austria, 27 September 2013
Rheumatology
Key words: Rheumatic diseases, osteoclasts, Phosphoinositide-3-Kinase, Phosphatase and tensin homolog [more]
Organism: Mouse
Tissue: Joint Tissue, Bone
Direct Comparison of Autologous and Allogeneic Transplantation of iPSC-Derived Neural Cells in the Brain of a Nonhuman Primate
Stem Cell Reports (Cell Press) Japan, 26 September 2013
Transplantation Medicine
Organism: Monkey
Tissue: Brain
Prognostic impact of tumor infiltrating CD8+ T cells in association with cell proliferation in ovarian cancer patients - a study of the OVCAD consortium
BMC Cancer (BioMed Central) Austria, Germany, Belgium, 17 September 2013
Oncology
Key words: Epithelial ovarian cancer, Cytotoxic T cells, Tumor proliferation, Prognostic impact, Residual tumor [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
A single extra copy of Dscr1 improves survival of mice developing spontaneous lung tumors through suppression of tumor angiogenesis
Cancer Letters (Elsevier) South Korea, 16 September 2013
Oncology
Key words: Down syndrome, cancer, angiogenesis, Dscr1, Spontaneous lung tumorigenesis [more]
Organism: Mouse
Tissue: Lung
Pathological State: Cancer
Contribution of Toll-Like Receptor 2 to the Innate Response against Staphylococcus aureus Infection in Mice
PLoS One (PLOS) Japan, China, 13 September 2013
Immunology
Key words: Staphylococcus aureus, macrophages, cytokines, bacterial pathogens, toll-like receptors, neutrophils, gene expression, blood [more]
Organism: Mouse
Tissue: Liver
Pathological State: Staphylococcus aureus Infection
Comprehensive characterizations of nanoparticle biodistribution following systemic injection in mice
Nanoscale (Royal Society of Chemistry) Taiwan, USA, 06 September 2013
Nanomedicine
Organism: Mouse
Tissue: Brain, Heart, Lung, Liver, Spleen, Kidney, Skin
Digital microscopy assessment of angiogenesis in different breast cancer compartments
BioMed Research International (Hindawi Publishing Corporation) Romania, Austria, 01 September 2013
Medical Image Analysis
Key words: Tumour angiogenesis, microvessel density, breast cancer, tumour associated stroma, tumour parenchyma, tumour invasive front. [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
In vitro and in vivo uptake study of Escherichia coli Nissle 1917 bacterial ghosts: cell-based delivery system to target ocular surface diseases
Investigative Ophthalmology & Visual Science (ARVO Journals) Austria, Serbia, Bulgaria, 01 September 2013
Microbiology
Organism: Guinea Pig
Tissue: Eye
Expression of E-cadherin, Twist, and p53 and their prognostic value in patients with oral squamous cell carcinoma
Journal of Cancer Research and Clinical Oncology (Springer) Taiwan, 30 August 2013
Oncology
Key words: Ttwist expression, betel quid, betel quid chewing, oscc tissue, reduced e-cadherin, oscc tumor, oral cancer, oral squamous cell carcinoma, oral carcinogenesis, neck cancer, oral epithelium, emt marker, bladder cancer, e-cadherin promoter, emt transcription [more]
Organism: Human
Tissue: Mucosa
Pathological State: Cancer
Involvement of the Serine Protease Inhibitor, SERPINE2, and the Urokinase Plasminogen Activator in Cumulus Expansion and Oocyte Maturation
PLoS One (PLOS) Taiwan, 30 August 2013
Reproductive Medicine
Key words: Oocytes, small interfering RNAs, extracellular matrix, immune serum, ovaries, vector cloning, complementary DNA, gene expression [more]
Organism: Human
Tissue: Ovaries
Glycogen synthase kinase-3β–mediated CCAAT/enhancer-binding protein delta phosphorylation in astrocytes promot es migration and activation of microglia/macrophages
Neurobiology of aging (Elsevier) Taiwan, Japan, 29 August 2013
Neuroscience
Key words: Alzheimer's disease, CEBPD, GSK3ß, astrocytes, microglia [more]
Organism: Mouse
Tissue: Brain
Human Cytomegalovirus UL76 Elicits Novel Aggresome Formation via Interaction with S5a of the Ubiquitin Proteasome System
Journal of Virology (American Society for Microbiology) China, 21 August 2013
Virology
Key words: Cytomegalovirus [more]
Organism: Human
Cell Line: HEK293T cells
Neohesperidin attenuates cerebral ischemia–reperfusion injury via inhibiting the apoptotic pathway and activating the Akt/Nrf2/HO-1 pathway
Journal of Asian Natural Products Research (Taylor and Francis) China, 16 August 2013
Neuroscience
Key words: Cerebral ischemia
Panton-Valentine Leukocidin Facilitates the Escape of Staphylococcus aureus From Human Keratinocyte Endosomes and Induces Apoptosis
The Journal of Infectious Diseases (Oxford University Press) Taiwan, 15 August 2013
Microbiology
Key words: Endosome keratinocyte, Panton-Valentine leukocidin, Staphylococcus aureus [more]
Organism: Rabbit
Tissue: Skin
Circulating alpha-klotho levels are not disturbed in patients with type 2 diabetes with and without macrovascular disease in the absence of nephropathy
Cardiovascular Diabetology (Springer) The Netherlands, Germany, 14 August 2013
Dermatology
Key words: Vascular, diabetes [more]
Organism: Mouse
Tissue: Kidney
Pathological State: Diabetes
Carboxyl-Terminal Modulator Protein Positively Regulates Akt Phosphorylation and Acts as an Oncogenic Driver in Breast Cancer
Cancer Research (AACR Publications) Taiwan, 13 August 2013
Oncology
Key words: Tumorigenesis, cancer cells, carboxy-terminal modulator protein, Akt serine/threonine kinase [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis
Cancer Cell (Cell Press) Austria, UK, Spain, 12 August 2013
Oncology
Key words: Cell cycle kinase CDK6, pro-angiogenic factor VEGF-A, tumor suppressor p16INK4a [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Quantitative magnetization transfer MRI of desmoplasia in pancreatic ductal adenocarcinoma xenografts
NMR in Biomedicine (Wiley) USA, 12 August 2013
Oncology
Key words: Quantitative magnetization transfer, bound proton fraction, desmoplasia, pancreatic cancer, xenograft [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Entry of human rhinovirus 89 via ICAM-1 into HeLa epithelial cells is inhibited by actin skeleton disruption and by bafilomycin
Archives of Virology (Springer) Austria, 04 August 2013
Virology
Key words: Hela cell, transferrin, rhabdomyosarcoma, confocal immunofluorescence microscopy, cholesterol depletion, dextran, skeletal muscle cell, stress fiber formation, actin aggregate, lipid raft, breast cancer cell line, infected hela cell, actin patch, rock inhibitor, capsid protein [more]
Organism: Human
Cell Line: HeLa cells
An interleukin-17–mediated paracrine network promotes tumor resistance to anti-angiogenic therapy
Nature Medicine (Nature) USA, 04 August 2013
Oncology
Key words: Cancer [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Interleukin-1β induced by Helicobacter pylori infection enhances mouse gastric carcinogenesis
Cancer Letters (Elsevier) Japan, South Korea, 03 August 2013
Oncology
Key words: Interleukin-1ß, gastric cancer, helicobacter pylori infection, inflammation [more]
Organism: Mouse
Tissue: Stomach
Pathological State: Cancer, Helicobacter pylori infection
Impact of constant storage temperatures and multiple warming cycles on the quality of stored red blood cells
VoxSanguinis (Wiley) Austria, 02 August 2013
Hematology
Key words: Electron microscopy, quality, RBC, storage, temperature. [more]
Organism: Human
Cell Line: Red blood cells
Decreased hippocampal MR/GR ratio is associated with low-birth weight in Cynomolgus macaque neonates
Journal of Molecular Endocrinology (Society for Endocrinology) Singapore, 01 August 2013
Reproductive Medicine
Key words: MR:GR ratio, cynomolgus macaque, glucocorticoid receptor, low birth weight [more]
Organism: Monkey
Tissue: Brain
Mobilizing monocytes to cross-present circulating viral antigen in chronic infection
The Journal of Clinical Investigation (American Society for Clinical Investigation) Singapore, UK, Italy, 01 August 2013
Immunology
Organism: Human
Cell Line: PBMCs
Infliximab induces downregulation of the IL-12/IL-23 axis in 6-sulfo-LacNac (slan)+ dendritic cells and macrophages
Journal of Allergy and Clinical Immunology (Elsevier) Austria, 25 July 2013
Allergy Research
Key words: Psoriasis, myeloid dendritic cells, 6-sulfo-LacNac, IL-12p40, TNF-a [more]
Organism: Human
Tissue: Skin
Pathological State: Psoriasis
Association of gamma-glutamyltransferase with severity of disease at diagnosis and prognosis of ovarian cancer
British Journal of Cancer (Nature) Austria, USA, 16 July 2013
Oncology
Key words: Ovarian cancer, Prognostic markers [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
High resolution MRI for non-invasive mouse lymph node mapping
Journal of Immunological Methods (Elsevier) USA, China, 11 July 2013
Immunology
Key words: Mouse, Lymph node, Lymphatic drainage, India ink, Magnetic resonance imaging [more]
Organism: Mouse
Tissue: Lymphoid Tissue
A phase I trial of aminolevulinic acid-photodynamic therapy for treatment of oral leukoplakia
Oral Oncology (Elsevier) USA, 08 July 2013
Oncology
Key words: Leukoplakia, aminolevulinic acid, photodynamic therapy, phase I, laser [more]
Organism: Human
Tissue: Mucosa
Pathological State: Leukoplakia
Vascular Injury Involves the Overoxidation of Peroxiredoxin Type II and Is Recovered by the Peroxiredoxin Activity Mimetic That Induces Reendothelialization
Circulation (AHA Journals) USA, South Korea, 02 July 2013
Cardiology
Key words: Coronary restenosis, endothelium, peroxiredoxins, reactive oxygen species, receptor protein-tyrosine kinases [more]
Organism: Human
Tissue: Blood Vessels
Overexpression of Lon contributes to survival and aggressive phenotype of cancer cells through mitochondrial complex I-mediated generation of reactive oxygen species
Cell Death & Disease (Nature) Taiwan, 20 June 2013
Oncology
Key words: Apoptosis, Cancer metabolism, Pathogenesis [more]
Organism: Human
Tissue: Mucosa
Pathological State: Cancer
THU0094 Treatment with BGP-15, a Novel Insulin Sensitizer Attenuates Collagen-Induced Arthritis in DBA/1 Mice
Annals of the Rheumatic Diseases (BMJ Journals) Austria, Hungary, 15 June 2013
Rheumatology
Key words: Arthritis
HPV16 activates the AIM2 inflammasome in keratinocytes
Archives of Dermatological Research (Springer) Germany, 14 June 2013
Dermatology
Key words: Hpv16 dna, aim2 inflammasome, cytosolic dna sensor, inflammasome activation, anal intraepithelial neoplasium, hpv dna, hpv infection, il-1 release, amphotericin, caspase-1 activation, cutaneous wart, il-1 secretion, gentamicin, viral dna, hpv16 18 [more]
Organism: Human
Tissue: Skin
Pathological State: HPV Infection
Glia, Poster. Cell proliferation, lineages and differentation
GLIA (Wiley) Denmark, Austria, Australia, 14 June 2013
Neuroscience
Key words: Cell proliferation, lineages, differentiation
A practical approach to immunotherapy of hepatocellular carcinoma using T cells redirected against hepatitis B virus
Molecular Therapy Nucleic Acids (Cell Press) Singapore, Sweden, USA, UK, 12 June 2013
Immunology, Virology
Key words: hepatitis B virus, hepatocellular carcinoma, mRNA electroporation, TCR gene therapy [more]
Organism: Mouse
Tissue: Spleen
Pathological State: Cancer
In vivo bioluminescence reporter gene imaging for the activation of neuronal differentiation induced by the neuronal activator neurogenin 1 (Ngn1) in neuronal precursor cells
European Journal of Nuclear Medicine and Molecular Imaging (Springer) South Korea, 11 June 2013
Neuroscience
Key words: Reporter gene imaging, vector complex, neuronal differentiation, neuronal marker map2, gaussia luciferase, stem cell therapy, human nsc, pluripotent stem cell, grafted stem cell, neural precursor cell, hela cell, neurite outgrowth, nucleic acid delivery, nude mouse, luciferase signal [more]
Organism: Human
Cell Line: F11 cells
SYK Inhibition Modulates Distinct PI3K/AKT- Dependent Survival Pathways and Cholesterol Biosynthesis in Diffuse Large B Cell Lymphomas
Cancer Cell (Cell Press) USA, 10 June 2013
Oncology
Key words: B cell receptor, diffuse large B cell lymphoma [more]
Organism: Human
Pathological State: Cancer
Cell Line: DLBCL cells
Histone acetyl transferase 1 is essential for mammalian development, genome stability, and the processing of newly synthesized histones H3 and H4
PLoS Genetics (PLOS) USA, Austria, 06 June 2013
Genetics
Key words: Histones, Acetylation, Chromatin, Lysine, DNA damage, Mouse models, DNA replication, Neonates [more]
Organism: Mouse
Tissue: Whole Organism
Clinical significance and evolution of hepatic HBsAg expression in HBeAg-positive patients receiving interferon therapy
Journal of Gastroenterology (Springer) Taiwan, 05 June 2013
Gastroenterology
Key words: Hbsag decline, hbsag expression, on-treatment hbsag, hbsag titer, hbsag clearance, serum hbsag, hbeag loss, hbeag-negative chb, hbv genotype, hbv dna, serum hbv-dna, hbeag-positive chb, hbsag quantification, architect hbsag, viral load [more]
Organism: Human
Tissue: Liver
Pathological State: Hepatitis B Virus Infection
Quantitative Evaluation of Stem Cell Grafting in the Central Nervous System of Mice by In Vivo Bioluminescence Imaging and Postmortem Multicolor Histological Analysis
Imaging and Tracking Stem Cells (Springer) Belgium, 04 June 2013
Stem Cell Research
Key words: Neural stem cells, mesenchymal stromal cells eGFP, luciferase, cell transplantation, brain, bioluminescence imaging, histology, microglia, astrocytes
Enhanced inhibition of prostate tumor growth by dual targeting the androgen receptor and the regulatory subunit type iα of protein kinase a in vivo
International Journal of Molecular Sciences (MDPI) Austria, Germany, 04 June 2013
Oncology
Key words: androgen receptor, cAMP-dependent protein kinase A, regulatory subunit type Iα, prostate cancer, antisense molecules, dual targeting, LNCaP xenografts, castration resistance [more]
Organism: Mouse
Tissue: Prostate, Xenograft Tumor
Pathological State: Cancer
Smooth muscle cell transplantation improves bladder contractile function in streptozocin-induced diabetic rats
Cytotherapy (Elsevier) Belgium, 01 June 2013
Transplantation Medicine
Key words: Bladder smooth muscle cells, cell graft survival, cell transplantation, contractile function, diabetes, in vivo cystometry [more]
Organism: Rat
Tissue: Bladder
Pathological State: Diabetes
Biocompatible fluorescent nanoparticles for in vivo stem cell tracking
Nanotechnology (IOP Science) Italy, Switzerland, 20 May 2013
Nanomedicine
Key words: fluorescent nanoparticles, in vivo stem cell tracking, hAFCs, methyl methacrylate (MMA) [more]
Organism: Human
Cell Line: hAFC cells
Increased Cdc7 expression is a marker of oral squamous cell carcinoma and overexpression of Cdc7 contributes to the resistance to DNA-damaging agents
Cancer Letters (Elsevier) Taiwan, 16 May 2013
Oncology
Key words: Cdc7, oral cancer, prognostic marker, chemotherapy resistance [more]
Organism: Human
Tissue: Mucosa
Pathological State: Cancer
Identification and Characterization of Poorly Differentiated Invasive Carcinomas in a Mouse Model of Pancreatic Neuroendocrine Tumorigenesis
PLoS One (PLOS) USA, Switzerland, 14 May 2013
Oncology
Key words: Insulin, differentiated tumors, invasive tumors, cell staining, insulinoma, immunofluorescence staining, carcinomas, cell differentiation [more]
Organism: Mouse
Tissue: Pancreas
Pathological State: Cancer
Gaseous Hydrogen Sulfide Protects against Myocardial Ischemia-Reperfusion Injury in Mice Partially Independent from Hypometabolism
PLoS One (PLOS) The Netherlands, 10 May 2013
Cardiology
Key words: Reperfusion, necrosis, blood pressure, fibrosis, heart rate, granulocytes, heart, oxygen [more]
Organism: Rat
Pathological State: Myocardial Ischemia
Cell Line: H9c2 cells
Determination of tumor-infiltrating CD8+ lymphocytes in human ovarian cancer
International Journal of gynecological pathology (Wolters Kluwer) Austria, 10 May 2013
Oncology
Key words: Tumor-infiltrating immune cells, ovarian cancer, CD8+ lymphocytes [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
Heparanase promotes lymphangiogenesis and tumor invasion in pancreatic neuroendocrine tumors
Oncogene (Nature) USA, Sweden, Israel, 06 May 2013
Oncology
Key words: Lymphangiogenesis, Oncogenesis, Pancreatic cancer [more]
Organism: Mouse
Tissue: Pancreas
Pathological State: Cancer
Selected Abstracts from the World Conference on Interventional Oncology (WCIO) 2013
Journal of Vascular and Interventional Radiology (Elsevier) , 01 May 2013
Oncology
Sex differences in IRF5 levels and implications for pDC IFN{alpha} response (P1365)
The Journal of Immunology (American Association of Immunologists) USA, 01 May 2013
Immunology
Key words: IRF5, Sex differences, pDC IFNα, HIV-1 [more]
Pathological State: HIV Infection
Nuclear Localization of CD26 Induced by a Humanized Monoclonal Antibody Inhibits Tumor Cell Growth by Modulating of POLR2A Transcription
PLoS One (PLOS) Japan, 29 April 2013
Oncology
Key words: Cancer treatment, mesothelioma, endocytosis, nuclear membrane, small interfering RNAs, immunoprecipitation, immunoblot analysis, cell membranes [more]
Organism: Human
Pathological State: Cancer
Cell Line: Malignant mesothelioma cell lines
Fluorescence endoscopy of cathepsin activity discriminates dysplasia from colitis
Inflammatory bowel Disease (Oxford University Press) USA, 15 April 2013
Gastroenterology
Key words: dysplasia, colitis, macrophages, cathepsin activity, fluorescence endoscopy [more]
Organism: Human
Tissue: Colon
Pathological State: Colitis
Intra-voxel incoherent motion MRI in rodent model of diethylnitrosamine-induced liver fibrosis
Magnetic Resonance Imaging (Elsevier) USA, 15 April 2013
Bioimaging
Key words: Intra-Voxel Incoherent Motion, Diffusion weighted MRI, Liver fibrosis [more]
Organism: Rat
Tissue: Liver
Pathological State: Liver Fibrosis
Non-Cell-Autonomous Tumor Suppression by p53
CELL (Cell Press) USA, Israel, 11 April 2013
Oncology
Key words: p53 tumor suppressor, hepatic stellate cells, hepatocellular carcinoma, premalignant cells [more]
Organism: Mouse
Tissue: Liver
Pathological State: Cancer
Oncogenic RAS pathway activation promotes resistance to anti-VEGF therapy through G-CSF–induced neutrophil recruitment
PNAS (PNAS) USA, 09 April 2013
Oncology
Key words: Agiogenesis microenvironment tyrosine kinase
Increased copy-number and not DNA hypomethylation causes overexpression of the candidate proto-oncogene CYP24A1 in colorectal cancer
International Journal of Cancer (Wiley) Austria, 05 April 2013
Oncology
Key words: CYP24A1, colorectal cancer, 20q13.2, methylation, proliferation [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Transcatheter delivery of sorafenib-eluting polylactide-co-glycolide microspheres: therapy response studies in a rat model of hepatocellular carcinoma
Journal of Vascular and Interventional Radiology (Elsevier) USA, 02 April 2013
Oncology
Key words: Sorafenib, hepatocellular carcinoma, polylactide-co-glycolide [more]
Organism: Rat
Tissue: Liver
Pathological State: Cancer
Excisional Wound Healing Is Delayed in a Murine Model of Chronic Kidney Disease
PLoS One (PLOS) USA, 25 March 2013
Nephrology
Key words: Chronic kidney disease, wound healing, kidneys, granulation tissue, angiogenesis, inflammation, renal failure, surgical and invasive medical procedures [more]
Organism: Mouse
Tissue: Kidney
Pathological State: Kidney Disease
Effects of Cholic Acid and its Derivatives in Experimental Arthritis
Annals of the Rheumatic Diseases (BMJ Journals) Austria, 20 March 2013
Rheumatology
Key words: Cholesterol metabolism, Collagen-induced arthritis, nor-ursodeoxycholic acid [more]
Organism: Mouse
Tissue: Joint Tissue, Bone
Pathological State: Rheumatoid Arthritis
Do High Molecular Weight Adiponectin Levels Associate with Radiographic Progression in early Rheumatoid Arthritis and Hand Osteoarthritis?
Annals of the Rheumatic Diseases (BMJ Journals) The Netherlands, 20 March 2013
Rheumatology
Key words: Adipokines, osteoarthritis, rheumatoid arthritis [more]
Organism: Mouse
Tissue: Bone
Pathological State: Rheumatoid Arthritis
The prognostic value of estrogen receptor beta and proline-, glutamic acid- and leucine-rich protein 1 (PELP1) expression in ovarian cancer
BMC Cancer (Springer) Austria, 14 March 2013
Oncology
Key words: Mucinous ovarian cancer, residual tumor load, mucinous eoc, eoc tissue, serous eoc, clear cell carcinoma, endometrioid tumor, breast cancer tissue, cytoreductive surgery, human eoc, endometrial cancer, serum ca-125, paraaortic lymphadenectomy, undifferentiated carcinoma, surgical staging [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
PI3K/AKT Signaling Is Essential for Communication between Tissue-Infiltrating Mast Cells, Macrophages, and Epithelial Cells in Colitis-Induced Cancer
Clinical Cancer Research (AACR Publications) USA, Germany, 13 March 2013
Oncology
Key words: Colitis, dysplasia, colorectal cancer, colonic submucosa, phosphoinositide 3-kinase [more]
Organism: Human
Tissue: Colon
Pathological State: Colitis, Cancer
Tumor STAT1 Transcription Factor Activity Enhances Breast Tumor Growth and Immune Suppression Mediated by Myeloid-derived Suppressor Cells
Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) USA, 13 March 2013
Oncology
Key words: Breast Cancer, immunosuppression, signal transduction, T Cell, tumor immunology, MDSC, STAT1, mouse model of breast cancer [more]
Organism: Human, Mouse
Tissue: Breast
Pathological State: Cancer
Type III Secretion of ExoU Is Critical during Early Pseudomonas aeruginosa Pneumonia
mBio (ASM) USA, 12 March 2013
Pulmonology
Key words: Eukaryotic cells, Many Gram-negative bacteria, Pseudomonas aeruginosa [more]
Organism: Mouse
Tissue: Lung
Pathological State: Pneumonia, Pseudomonas Infection
Rapid dramatic alterations to the tumor microstructure in pancreatic cancer following irreversible electroporation ablation
Nanomedicine (Future Medicine) USA, 12 March 2013
Nanomedicine
Key words: Immunohistochemistry apoptosis, IRE-treated tumors [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Late Infusion of Cloned Marrow Fibroblasts Stimulates Endogenous Recovery from Radiation-Induced Lung Injury
PLoS One (PLOS) USA, 08 March 2013
Regenerative Medicine
Key words: Dogs, pulmonary imaging, computed axial tomography, stem cells, fibroblasts, endothelial cells, pulmonary function, reverse transcriptase-polymerase chain reaction [more]
Organism: Dog
Tissue: Lung
Pathological State: Radiation-induced lung injury
Quantitative measurement of the androgen receptor in prepuces of boys with and without hypospadias
BJU International (Wiley) Austria, 07 March 2013
Endocrinology
Key words: Hypospadias, aetiology, androgen receptor, genetics, signalling [more]
Organism: Human
Tissue: Prostate
Pathological State: Hypospadias
FRI0270 Development of systemic lupus-like disease in regulatory T cells (TREG)-deficient scurfy mice
Annals of the Rheumatic Diseases (BMJ Journals) Austria, Germany, 01 March 2013
Rheumatology
Key words: Lupus, T cells [more]
Organism: Mouse
Tissue: Skin
Pathological State: Lupus
The 10th International Congress on SLE
Lupus (SAGE Journals) USA, 01 March 2013
Rheumatology
Key words: Pro-inflammatory HDL, subclinical atherosclerosis, NGAL (lipocalin-2)
Hyaluronan enhances bone marrow cell therapy for myocardial repair after infarction
Molecular Therapy (Cell Press) Taiwan, 01 March 2013
Cardiology
Organism: Rat
Tissue: Heart
Pathological State: Myocardial Infarction
Human Umbilical Vein Endothelial Cells Protect Against Hypoxic-Ischemic Damage in Neonatal Brain via Stromal Cell-derived Factor 1/C-X-C Chemokine Receptor Type 4
Stroke (AHA Journals) Taiwan, 28 February 2013
Neuroscience
Key words: Human umbilical vein endothelial cell, neonatal brain, neurovascular unit, SDF-1/CXCR4 [more]
Organism: Rat, Human
Tissue: Brain
Pathological State: Cerebral ischemia
Cell Line: HUVECs (Human umbilical vein endothelial cells)
Noninvasive and Targeted Gene Delivery into the Brain Using Microbubble-Facilitated Focused Ultrasound
PLoS One (PLOS) Taiwan, 27 February 2013
Nanomedicine
Key words: Viral vectors, magnetic resonance imaging, central nervous system, astrocytes, gene delivery, gene expression, acoustics, neurons [more]
Organism: Mouse
Tissue: Brain
Abatacept (CTLA-4IG) treatment reduces the migratory capacity of monocytes in patients with rheumatoid arthritis
Arthritis & Rheumatology (Wiley) Austria, 25 February 2013
Rheumatology
Key words: Antigen-presenting cells, CTLA-4Ig, Peripheral blood mononuclear cells [more]
Organism: Human
Pathological State: Rheumatoid Arthritis
Cell Line: PBMCs
Tumor necrosis factor–inhibiting therapy preferentially targets bone destruction but not synovial inflammation in a tumor necrosis factor–driven model of rheumatoid arthritis
Arthritis & Rheumatology (Wiley) Austria, USA, 25 February 2013
Rheumatology
Key words: Tumor necrosis factor, osteoclastogenesis in vitro, cell–derived monocytes [more]
Organism: Mouse
Tissue: Joint Tissue, Bone
Pathological State: Rheumatoid Arthritis
Adipose stromal cells primed with hypoxia and inflammation enhance cardiomyocyte proliferation rate in vitro through STAT3 and Erk1/2
Journal of Translational Medicine (Springer) The Netherlands, 13 February 2013
Cardiology
Key words: hl-1 cardiomyocyte, hl-1 cell, jak stat inhibitor, cardiomyocyte proliferation, cardiomyocyte proliferation, cardiomyocyte proliferation, cardiomyocyte proliferation, cardiomyocyte proliferation, cardiomyocyte proliferation, cardiomyocyte proliferation, cardiomyocyte proliferation, cardiomyocyte proliferation [more]
Organism: Human
Cell Line: Cardiomyocytes
Automated REcognition of Tissue-associated Erythrocytes (ARETE)—a new tool in tissue cytometry
Cytometry Part A (Wiley) Austria, 11 February 2013
Medical Image Analysis
Key words: Erythrocytes, immunofluorescence microscopy, autofluorescence, tissue cytometry, automated image analysis, boosted decision trees of Haar-like features, machine learning, placenta, colorectal cancer [more]
Organism: Human
Tissue: Colon
Characterization of Transcriptional Changes in ERG Rearrangement-Positive Prostate Cancer Identifies the Regulation of Metabolic Sensors Such as Neuropeptide Y
PLoS One (PLOS) Austria, Germany, 04 February 2013
Oncology
Key words: Prostate cancer, gene expression, meta-analysis, prostate gland, gene regulation, microarrays, cell metabolism, glucose metabolism [more]
Organism: Human
Tissue: Prostate
Pathological State: Cancer
Circulating Metastasis Promoting Protein S100A4 in Idiopathic Inflammatory Myopathies
Annals of the Rheumatic Diseases (BMJ Journals) Czech Republic, 02 February 2013
Rheumatology
Key words: Protein S100A4, rheumatoid arthritis, psoriasis
Oestrogens improve human pancreatic islet transplantation in a mouse model of insulin deficient diabetes
Diabetologia (Springer) USA, China, 01 February 2013
Endocrinology
Key words: Ffunctional vessel density, human alpha cell, human islet graft, beta cell regeneration, beta cell apoptosis, islet transplantation, islet yield, sirolimus, islet engraftment, apoptotic beta cell, cultured human islet, beta cell proliferation, tacrolimus, mouse islet, insulin independence [more]
Organism: Mouse
Tissue: Kidney
Pathological State: Diabetes
Long course hyperbaric oxygen stimulates neurogenesis and attenuates inflammation after ischemic stroke
Mediators of Inflammation (Hindawi Publishing Corporation) Taiwan, 15 January 2013
Neuroscience
Organism: Rat
Tissue: Brain
Pathological State: Cerebral Ischemia
Cystathionine γ-Lyase Protects against Renal Ischemia/Reperfusion by Modulating Oxidative Stress
Journal of The American Society of Nephrology (JASN) Canada, UK, The Netherlands, 02 January 2013
Nephrology
Key words: Cystathionine γ-lyase, tubulointerstitium, glomeruli, renal ischemia
Tumor-specific expression of organic anion-transporting polypeptides: transporters as novel targets for cancer therapy
Journal of drug delivery (Hindawi Publishing Corporation) Austria, Switzerland, Greece, 01 January 2013
Oncology
Organism: Human
Tissue: Pancreas
Pathological State: Cancer
The role of glucocorticoid receptors in dexamethasone-induced apoptosis of neuroprogenitor cells in the hippocampus of rat pups
Mediators of Inflammation (Hindawi Publishing Corporation) Taiwan, 01 January 2013
Neuroscience
Organism: Rat
Tissue: Brain
The effect of pioglitazone on non-pregnant female genital tract in experimental diabetes mellitus
The Medical-Surgical Journal (revmedchir) Romania, 01 January 2013
Reproductive Medicine
Key words: DIABETES MELLITUS, STREPTOZOTOCIN, PIOGLITAZONE, OVARY [more]
Pathological State: Diabetes
MAGNESIUM AND ZINC INFLUENCE ON FEMALE GENITAL TRACT IN EXPERIMENTAL INDUCED DIABETES MELLITUS.
Romanian Journal of Functional and Clinical, Macro- and Microscopical Anatomy and of Anthropology () Romania, 01 January 2013
Reproductive Medicine
Pathological State: Diabetes
Tracing Conidial Fate and Measuring Host Cell Antifungal Activity Using a Reporter of Microbial Viability in the Lung
Cell Reports (Cell Press) USA, Japan, 27 December 2012
Virology
Key words: FLARE conidia, C-type lectin receptor, leukocyte-fungal cell [more]
Organism: Mouse
Tissue: Lung
Pathological State: Fungal Infection
Comprehensive morphometric analysis of mononuclear cell infiltration during experimental renal allograft rejection
Transplant Immunology (Elsevier) Germany, 23 December 2012
Transplantation Medicine
Key words: B-cells, different analysis methods, experimental renal allograft rejection, macrophages, T-cells [more]
Organism: Rat
Tissue: Kidney
Pathological State: Allogeneic Transplantation
Ectopic Pregnancy-Derived Human Trophoblastic Stem Cells Regenerate Dopaminergic Nigrostriatal Pathway to Treat Parkinsonian Rats
PLoS One (PLOS) Taiwan, 21 December 2012
Stem Cell Research
Key words: Neurons, pluripotency, flow cytometry, pregnancy, dopamine, dopaminergics, rats, cell differentiation [more]
Organism: Rat
Tissue: Brain
Pathological State: Parkinson's Disease
Enhancement of the Immunogenicity and Protective Efficacy of a Mucosal Influenza Subunit Vaccine by the Saponin Adjuvant GPI-0100
PLoS One (PLOS) The Netherlands, 17 December 2012
Immunology
Key words: Vaccines, immunologic adjuvants, influenza, immune response, antibodies, antibody response, influenza viruses, viral vaccines [more]
Organism: Mouse
Tissue: Lung
Pathological State: Influenza Infection
Spatiotemporal evolution of early innate immune responses triggered by neural stem cell grafting
Stem Cell Research & Therapy (BMC) Belgium, 14 December 2012
Stem Cell Research
Key words: Anti-APC (Adenomatous polyposis coli protein) antibody, central nervous system, enhanced green fluorescent protein, neuronal nuclei [more]
Organism: Mouse
Tissue: Brain
CHC promotes tumor growth and angiogenesis through regulation of HIF-1α and VEGF signaling
Cancer Letters (Elsevier) Taiwan, 07 December 2012
Oncology
Key words: Pancreatic cancer, monoclonal antibody, clathrin heavy chain, HIF-1a, angiogenesis [more]
Organism: Human
Tissue: Pancreas
Pathological State: Cancer
Depletion of tristetraprolin in breast cancer cells increases interleukin-16 expression and promotes tumor infiltration with monocytes/macrophages
Carcinogenesis (Oxford University Press) Germany, 04 December 2012
Oncology
Key words: RNA-binding protein tristetraprolin, macrophages, interleukin-16, granulocyte macrophage-colony
Stem Cell-Like Differentiation Potentials of Endometrial Side Population Cells as Revealed by a Newly Developed In Vivo Endometrial Stem Cell Assay
PLoS One (PLOS) Japan, 04 December 2012
Stem Cell Research
Key words: Stem cells, cell differentiation, kidneys, stem cell transplantation, endometrium, flow cytometry, stem cell niche, renal transplantation [more]
Organism: Mouse
Tissue: Kidney
Towards the Automated Detection and Characterization of Osteoclasts in Microscopic Images
Principles of Osteoimmunology (Springer) Austria, 01 December 2012
Medical Image Analysis
Key words: Giant Cell Tumor, Joint Photographic Expert Group, Portable Network Graphic, Biological Expert, Osteoclast Culture [more]
Organism: Human
Cell Line: Osteoclasts
Crypts detection in microscopic images using hierarchical structures
Pattern Recognition Letters (Elsevier) Romania, Austria, 29 November 2012
Pathology
Key words: Crypt segmentation, morphological hierarchy, morphological pyramid, biomedical imaging, pathology, microscopy [more]
Organism: Human
Tissue: Colon
The in Vivo Imaging Platform for Cell Tracking in the Stem Cell-Induced Immune Tolerance to Vascularized Composite Allotransplantation: 1756
Transplantation (Wolters Kluwer) China, 27 November 2012
Microscopy
Organism: Rat
Tissue: Whole Organism
Pathological State: Allogeneic Transplantation
Proteinuria triggers renal lymphangiogenesis prior to the development of interstitial fibrosis
PLoS One (PLOS) The Netherlands, 26 November 2012
Nephrology
Key words: Lymph, Proteinuria, Kidneys, Fibrosis, Macrophages, Fibroblasts, Epithelial cells, Collagens [more]
Organism: Rat
Tissue: Kidney
Pathological State: Renal Fibrosis
Higher thymocyte selection-associated high mobility group box (TOX) expression predicts poor prognosis in patients with ovarian cancer
BMC cancer (BMC) China, 25 November 2012
Oncology
Key words: Ovarian cancer, TOX, CD8 + T cell, Prognosis [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
Epithelial Cell Adhesion Molecule Regulates Tumor Initiation and Tumorigenesis via Activating Reprogramming Factors and Epithelial-Mesenchymal Transition Gene Expression in Colon Cancer
Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) Taiwan, 16 November 2012
Oncology
Key words: Cancer Biology, Cancer Stem Cells, Cancer Tumor, Promoter Oncogene, Stem Cells EpCAM, Epithelial-Mesenchymal Transition, Reprogramming Factor Tumor-initiating, Cells Tumorsphere [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Photodynamic Control of Bioactivity in a Nanofiber Matrix
ACS NANO (ACS Publications) USA, 15 November 2012
Nanomedicine
Key words: Supramolecular nanofibers, cell morphological analysis, nitrobenzyl, projected cell area, photodegradable, RGDS epitope [more]
Organism: Mouse
Cell Line: NIH 3T3 mouse embryonic fibroblasts
Valproic Acid Induces Cutaneous Wound Healing In Vivo and Enhances Keratinocyte Motility
PLoS One (PLOS) South Korea, 07 November 2012
Dermatology
Key words: Wound healing, keratinocytes, collagens, keratins, ERK signaling cascade, Wnt signaling cascade, immunohistochemical analysis, beta-catenin signaling [more]
Organism: Mouse
Tissue: Skin
Pathological State: Cutaneous wound
SOCS-3 is downregulated in progressive CKD patients and regulates proliferation in human renal proximal tubule cells in a STAT1/3 independent manner
Laboratory Investigation (Nature) Austria, 29 October 2012
Physiology
Key words: Cell proliferation, Cell signalling, Chronic kidney disease [more]
Organism: Human
Tissue: Kidney
Pathological State: Kidney Disease
Modulation of STAT-3 in rheumatoid synovial T cells suppresses Th17 differentiation and increases the proportion of Treg cells
Arthritis & Rheumatology (Wiley) South Korea, 27 October 2012
Rheumatology
Key words: STAT-3–mediated regulation, rheumatoid arthritis, CD4+ T cells, synovial fluid [more]
Organism: Human
Pathological State: Rheumatoid Arthritis
Cell Line: PBMCs
Bone regeneration with low dose BMP-2 amplified by biomimetic supramolecular nanofibers within collagen scaffolds
Biomaterials (Elsevier) USA, 22 October 2012
Regenerative Medicine
Key words: Peptide amphiphile, heparin, heparan sulfate, BMP-2 (bone morphogenetic protein-2), regenerative medicine, bone regeneration [more]
Organism: Rat
Tissue: Bone
Establishing an allergic eczema model employing recombinant house dust mite allergens Der p 1 and Der p 2 in BALB/c mice
Experimental Dermatology (Wiley) Austria, Belgium, 15 October 2012
Dermatology
Key words: Allergic eczema, atopic eczema, Der p1 and Der p 2, house dust mite, protease activity, recombinant allergens [more]
Organism: Mouse
Tissue: Skin
Pathological State: Eczema
PDGFR blockade is a rational and effective therapy for NPM-ALK–driven lymphomas
Nature Medicine (Nature) Austria, USA, UK, Italy, 14 October 2012
Oncology
Key words: Mechanism of action, Non-hodgkin lymphoma, Therapeutics [more]
Organism: Human
Tissue: Lymphoid Tissue
Pathological State: Cancer
Prospero Homeobox 1 Promotes Epithelial–Mesenchymal Transition in Colon Cancer Cells by Inhibiting E-cadherin via miR-9
Clinical Cancer Research (AACR Publications) Taiwan, 08 October 2012
Oncology
Key words: Prospero homeobox 1, matrix metalloproteinase activity, epithelial–mesenchymal transition [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Investigation of the Relationship Between Prostate Cancer and MSMB and NCOA4 Genetic Variants and Protein Expression
Human Mutation (Wiley) USA, Canada, 04 October 2012
Oncology
Key words: Prostate cancer, MSMB, PSP94, NCOA4 [more]
Organism: Human
Tissue: Prostate
Pathological State: Cancer
γ-secretase inhibitors prevent overgrowth of transplanted neural progenitors derived from human-induced pluripotent stem cells
Stem Cells and Development (Mary Ann Liebert Inc.) Japan, 28 September 2012
Regenerative Medicine
Organism: Mouse
Tissue: Brain
Brief Report: Amelioration of collagen-induced arthritis in mice by lentivirus-mediated silencing of microRNA-223
Arthritis & Rheumatology (Wiley) Taiwan, 27 September 2012
Rheumatology
Key words: MicroRNA, MiRNA-223, rheumatoid arthritis, osteoarthritis, reverse transcriptase–polymerase chain reaction [more]
Organism: Mouse
Tissue: Joint Tissue, Bone
Pathological State: Rheumatoid Arthritis
A global downregulation of microRNAs occurs in human quiescent satellite cells during myogenesis
Differentiation (Elsevier) The Netherlands, 26 September 2012
Developmental Biology
Key words: Satellite cells, Skeletal muscle, Quiescence, MicroRNA, MicroRNA microarray [more]
Organism: Human
Tissue: Muscle
Male Microchimerism in the Human Female Brain
PLoS One (PLOS) USA, 26 September 2012
Neuroscience
Key words: Alzheimer disease, brain diseases, pregnancy, natural history of disease, amygdala, frontal lobe, washington, Y chromosomes [more]
Organism: Mouse
Tissue: Brain
Improved assessment of frozen/thawed mouse spermatozoa using fluorescence microscopy
Journal of veterinary science (Kamje Press) Germany, 20 September 2012
Reproductive Medicine
Key words: cryopreservation, fluorescence microscopy, genetically modified (GM) mice, membrane integrity, 3Rs
Comparative Secretome Analyses Using a Hollow Fiber Culture System with Label-Free Quantitative Proteomics Indicates the Influence of PARK7 on Cell Proliferation and Migration/Invasion in Lung Adenocarcinoma
Journal of Proteome Research (ACS Publications) Taiwan, 17 September 2012
Oncology
Key words: Hollow fiber culture system, label-free quantitative proteomics, PARK7, cancer metastasis [more]
Organism: Human
Tissue: Lung
Pathological State: Cancer
Honey bee (Apis mellifera) venom induces AIM2 inflammasome activation in human keratinocytes
Allergy (Wiley) Germany, 13 September 2012
Allergy Research
Key words: AIM2 inflammasome, allergic reaction, cytosolic DNA, honey bee venom, keratinocytes [more]
Organism: Human
Cell Line: Epidermal keratinocytes
Prevention of preneoplastic lesions by dietary vitamin D in a mouse model of colorectal carcinogenesis
The Journal of Steroid Biochemistry and Molecular Biology (Elsevier) Austria, UK, 11 September 2012
Oncology
Key words: Vitamin D, colorectal cancer, dysplasia, chemoprevention, cyp24a1, cyp27b1 [more]
Organism: Mouse
Tissue: Colon
Quantitative Immunofluorescence Reveals the Signature of Active B-cell Receptor Signaling in Diffuse Large B-cell Lymphoma
Clinical Cancer Research (AACR Publications) USA, 10 September 2012
Oncology
Key words: B-cell receptor, diffuse large B-cell lymphomas, DLBCL pathogenesis [more]
Organism: Human
Tissue: Lymphoid Tissue
Pathological State: Cancer
Isolation and phenotypic characterisation of stem cells from late stage osteoarthritic mesenchymal tissues
Current stem cell research and Therapy (Ingentaconnect) Romania, 01 September 2012
Stem Cell Research
Key words: Chondrogenesis, mesenchymal stem cells, osteoarthritis, regenerative medicine. [more]
Organism: Human
Tissue: Bone, Adipose Tissue
Pathological State: Osteoarthritis
The use of a tumor metastasis targeting peptide to deliver doxorubicin-containing liposomes to highly metastatic cancer
Biomaterials (Elsevier) China, 30 August 2012
Nanomedicine
Key words: Highly metastatic tumor, targeting, nanomedicine, liposomes, delivery [more]
Organism: Mouse
Tissue: Breast, Xenograft Tumor
Pathological State: Cancer
Neuron-Specific Prolyl-4-Hydroxylase Domain 2 Knockout Reduces Brain Injury After Transient Cerebral Ischemia
Stroke (AHA Journals) Germany, 28 August 2012
Neuroscience
Key words: HIF-1, hypoxia, neuroprotection, PHD, stroke [more]
Organism: Mouse
Tissue: Brain
Pathological State: Cerebral Ischemia
Epithelial-to-Mesenchymal Transition Leads to Docetaxel Resistance in Prostate Cancer and Is Mediated by Reduced Expression of miR-200c and miR-205
The American Journal of Pathology (Elsevier) China, 11 August 2012
Oncology
Key words: Docetaxel, (miR)-200c, miR-205, E-cadherin, Systemic polychemotherapy [more]
Organism: Human
Tissue: Prostate
Pathological State: Cancer
Quantitative and phenotypic analysis of mesenchymal stromal cell graft survival and recognition by microglia and astrocytes in mouse brain
Immunobiology (Elsevier) Belgium, 09 August 2012
Immunology
Key words: Astrocytes, brain, cell transplantation, mesenchymal stromal cell, microglia [more]
Organism: Mouse
Tissue: Brain
A mouse model to identify cooperating signaling pathways in cancer
Nature Methods (Nature) Austria, Spain, 05 August 2012
Oncology
Key words: animal disease models, Cancer genetics, Mouse [more]
Organism: Mouse
Tissue: Lung, Pancreas, Skin
Pathological State: Cancer
Activation of Notch Signaling During Ex Vivo Expansion Maintains Donor Muscle Cell Engraftment
Stem Cells (Wiley) USA, 03 August 2012
Stem Cell Research
Key words: Striated muscle, satellite cells, regeneration, primary cell culture, notch ligand, cell transplantation [more]
Organism: Mouse
Tissue: Muscle
Coordinated roles of ST3Gal-VI and ST3Gal-IV sialyltransferases in the synthesis of selectin ligands
Blood (American Society of Hematology) USA, Germany, 02 August 2012
Hematology
Key words: Leukocyte trafficking, ST3Gal subfamily, protein glycosylation [more]
Organism: Mouse
Tissue: Lymphoid Tissue
Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43
PNAS (PNAS) USA, 02 August 2012
Neuroscience
Key words: Protein aggregation, neuronal apoptosis
Chapter 9 - Correlated Light Microscopy and Electron Microscopy
Methods in Cell Biology (Elsevier) The Netherlands, 31 July 2012
Microscopy
Key words: Light microscopy, electron microscopy, correlated microscopy, orientation, probes, high resolution, drawing tube, mosaic microscopy
Abstracts for the International Federation of Placenta Associations Meeting 2012
Placenta (Elsevier) , 25 July 2012
Reproductive Medicine
Vasohibin-2 Expressed in Human Serous Ovarian Adenocarcinoma Accelerates Tumor Growth by Promoting Angiogenesis
Molecular Cancer Research (AACR Publications) Japan, 23 July 2012
Oncology
Key words: Vasohibin-1, angiogenesis, ovarian cancer, Angiopoietins [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
The vitamin D receptor activator paricalcitol prevents fibrosis and diastolic dysfunction in a murine model of pressure overload
The Journal of Steroid Biochemistry and Molecular Biology (Elsevier) The Netherlands, 15 July 2012
Cardiology
Key words: Fibrosis, heart failure, paricalcitol, remodeling, vitamin D receptor, renin [more]
Organism: Mouse
Tissue: Heart
Pathological State: Cardiac Fibrosis
Tumour‐secreted miR‐9 promotes endothelial cell migration and angiogenesis by activating the JAK‐STAT pathway
EMBO Journal (EMBO press) USA, 06 July 2012
Oncology
Key words: Angiogenesis, Endothelium, JAK‐STAT, MicroRNA, Tumour [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
1107 In Vitro Generated Human Dendritic Cells Exposed to a Potent Maturation Melanoma Cell Lines Lysate Show a Tolerogenic-like Phenotype and Functionality When Exposed to Dexamethasone Prior to the Maturation Stimuli
European Journal of Cancer (Elsevier) , 06 July 2012
Oncology
1110 Modulation of Genistein- and Resveratrol-induced Apoptosis and Cell Proliferation in Colon Cancer Cells
European Journal of Cancer (Elsevier) , 06 July 2012
Oncology
1109 Density and Organization of B Cells, Including the Activation-induced Cytidine Deaminase (AID)-positive Sub-population, Within Active Tumor Border of Human Colorectal Cancer Liver Metastases Shows a Positive Association With Survival Prognosis
European Journal of Cancer (Elsevier) , 06 July 2012
Oncology
1108 Histidine-rich Glycoprotein Regulates Macrophage Differentiation
European Journal of Cancer (Elsevier) , 06 July 2012
Oncology
Pristane-induced lupus as a model of human lupus arthritis: evolvement of autoantibodies, internal organ and joint inflammation
Lupus (SAGE Journals) Austria, 01 July 2012
Rheumatology
Key words: Lupus arthritis pristane-induced lupus (PIL), systemic lupus erythematosus (SLE) [more]
Organism: Mouse
Tissue: Joint Tissue, Bone, Lung, Kidney
Pathological State: Arthritis, Lupus
A Novel Nucleus-Based Classifier for Discrimination of Osteoclasts and Mesenchymal Precursor Cells in Mouse Bone Marrow Cultures
International Journal of Medical and Health Sciences (Open Science Index) Austria, 01 July 2012
Osteology
Key words: osteoclasts, machine learning, ellipse fitting.