Customer Publications (A total of 2213 papers published)

Suppression of NADPH oxidase- and mitochondrion-derived superoxide by Notoginsenoside R1 protects against cerebral ischemia–reperfusion injury through estrogen receptor-dependent activation of Akt/Nrf2 pathways

X Meng, M Wang, X Wang, G Sun, J Ye, H Xu, X Sun

Free Radical Research (Taylor and Francis) China, 20 May 2015

Neuroscience

Key words: Cerebral ischemia–reperfusion injury, oxidative stress, apoptosis, superoxide, NADPH oxidase [more]

Hypoxia-preconditioned mesenchymal stem cells attenuate bleomycin-induced pulmonary fibrosis

Ying-Wei Lan, Kong-Bung Choo, Chuan-Mu Chen, Tsai-Hsien Hung, Young-Bin Chen, Chung-Hsing Hsieh, Han-Pin Kuo, Kowit-Yu Chong

Stem Cell Research & Therapy (BMC) China, Malaysia, 20 May 2015

Stem Cell Research

Key words: Bleomycin, diopathic pulmonary fibrosis, hypoxia-inducible factor, hepatocyte growth factor, connective tissue growth factor [more]

Texture analysis of 125I-A5B7 anti-CEA antibody SPECT differentiates metastatic colorectal cancer model phenotypes and anti-vascular therapy response

V Rajkumar, V Goh, M Siddique, M Robson, G Boxer, RB Pedley, GJR Cook

British Journal of Cancer (Wiley) UK, 19 May 2015

Oncology

Key words: Cancer models, Colorectal cancer Computed tomography Tumour heterogeneity [more]

Intracellular calcium levels as screening tool for nanoparticle toxicity

Claudia Meindl, Tatjana Kueznik, Martina Bösch, Eva Roblegg, Eleonore Fröhlich

Journal of Applied Toxicology (Wiley) Austria, 14 May 2015

Toxicology

Key words: Nanoparticles, cytotoxicity, apoptosis, lysosomes, calcium imaging [more]

Expression of Interferon γ by Decidual Cells and Natural Killer Cells at the Human Implantation Site

Chie-Pein Chen,Longzhu Piao, Xilin Chen, Jianhua Yu, Rachel Masch, Frederick Schatz, Charles J Lockwood, S Joseph Huang

Reproductive Sciences (SAGE Journals) Taiwan, USA, 11 May 2015

Reproductive Medicine

Key words: Interferon γ, NK cells, decidual cells [more]

K-Ras stabilization by estrogen via PKCδ is involved in endometrial tumorigenesis

KH Koo, WJ Jeong, YH Cho, JC Park, DS Min, KY Choi

Oncotarget (Impact Journals) South Korea, 08 May 2015

Oncology

Key words: endometrial cancer, estrogen, tumorigenesis, K-Ras, PKCδ [more]

The systemic multiplication of Gallibacterium anatis in experimentally infected chickens is promoted by immunosuppressive drugs which have a less specific effect on the depletion of leukocytes

Surya Paudel, Claudia Hess, Patricia Wernsdorf, Tobias Käser, Sarah Meitz, Erika Jensen-Jarolim, Michael Hess, Dieter Liebhart

Veterinary Immunology and Immunopathology (Elsevier) Austria, 08 May 2015

Immunology

Key words: Gallibacterium anatis, chickensc, leukocyte quantification, non-selective immunosuppression [more]

siRNA-based spherical nucleic acids reverse impaired wound healing in diabetic mice by ganglioside GM3 synthase knockdown

Pratik S Randeria, Mark A Seeger, Xiao-Qi Wang, Heather Wilson, Desmond Shipp, Chad A Mirkin, Amy S Paller

PNAS (PNAS) USA, 05 May 2015

Dermatology

Key words: SNA, nanoparticle, siRNA, GM3 synthase, diabetic wound healing [more]

CCL7 contributes to the TNF-alpha-dependent inflammation of lesional psoriatic skin

Patrick M Brunner, Elisabeth Glitzner, Baerbel Reininger, Irene Klein, Georg Stary, Michael Mildner, Pavel Uhrin, Maria Sibilia, Georg Stingl

Experimental Dermatology (Wiley) Austria, 04 May 2015

Dermatology

Key words: CCL7, chemokines, myeloid cells, psoriasis, TNF-α [more]

Effect of Sodium-Glucose Cotransport Inhibition on Polycystic Kidney Disease Progression in PCK Rats

Sarika Kapoor, Daniel Rodriguez, Meliana Riwanto, Ilka Edenhofer, Stephan Segerer, Katharyn Mitchell, Rudolf P Wüthrich

PLoS One (PLOS) Switzerland, 30 April 2015

Nephrology

Key words: sodium-glucose-cotransporter-2 (SGLT2), polycystic kidney disease, aquaretic drug tolvaptan [more]

Frontal cortex and hippocampus neurotransmitter receptor complex level parallels spatial memory performance in the radial arm maze

Bharanidharan Shanmugasundaram, Ajinkya Sase, András G Miklosi, Fernando J Sialana, Saraswathi Subramaniyan, Yogesh D Aher, Marion Gröger, Harald Höger, Keiryn L Bennett, Gert Lubec

Behavioural Brain Research (Elsevier) Austria, 28 April 2015

Neuroscience

Key words: Radial arm maze, Neurotransmitter receptor complex, Blue native PAGE, Spatial memory, D1-GluN1 complex [more]

Oncogenic role of miR-155 in anaplastic large cell lymphoma lacking the t(2,5) translocation

Olaf Merkel, Frank Hamacher, Robert Griessl, Lisa Grabner, Ana-Iris Schiefer, Nicole Prutsch, Constance Baer, Gerda Egger, Michaela Schlederer, Peter William Krenn, Tanja Nicole Hartmann, Ingrid Simonitsch-Klupp, Christoph Plass, Philipp Bernhard Staber, Richard Moriggl, Suzanne D Turner, Richard Greil, Lukas Kenner

The Journal of Pathology (Wiley) Germany, Austria, UK, 27 April 2015

Oncology

Key words: miR-155, ALCL, ALK kinase, cytokines, IL-21, IL-22, IL-10 [more]

Enhancer of zeste homolog-2 (EZH2) methyltransferase regulates transgelin/smooth muscle-22α expression in endothelial cells in response to interleukin-1β and transforming growth factor-β2

Monika Maleszewska, Rutger AF Gjaltema, Guido Krenning, Martin C Harmsen

Cellular Signalling (Elsevier) The Netherlands, 24 April 2015

Cell Biology

Key words: Endothelial cell, EZH2, SM22α, inflammation, fibrosis, chromatin [more]

Deoxycholate bile acid directed synthesis of branched Au nanostructures for near infrared photothermal ablation

Dong-Hyun Kima, Andrew C Larson

Biomaterials (Elsevier) USA, 17 April 2015

Nanomedicine

Key words: Gold nanoparticles, bile acid, green chemistry, photothermal treatment, nanomedicine [more]

A-kinase-anchoring proteins coordinate inflammatory responses to cigarette smoke in airway smooth muscle

Wilfred J Poppinga, Irene H Heijink, Laura J Holtzer, Philipp Skroblin, Enno Klussmann, Andrew J Halayko, Wim Timens, Harm Maarsingh, Martina Schmidt

American Journal of Physiology (APS Journals) The Netherlands, Germany, Canada, USA, 15 April 2015

Pulmonology

Key words: CX3CR1, cuprizone, demyelination, spectroscopy, MRI [more]

Cytotoxity of nanoparticles is influenced by size, proliferation and embryonic origin of the cells used for testing

Eleonore Fröhlich, Claudia Meindl, Eva Roblegg, Antonia Griesbacher, Thomas R Pieber

Nanotoxicology (Taylor and Francis) Austria, 13 April 2015

Toxicology

Key words: Calcium-sensing receptor, tumor suppressor, colon Inflammation, cancer EMT, cancer stem cell, calcimimetic [more]

Der p2 internalization by epithelium synergistically augments toll-like receptor-mediated proinflammatory signaling

SC Yin, EC Liao, CL Chiu, CY Chang, JJ Tsai

Allergy, Asthma and Immunology Research (Kamje Press) Taiwan, 10 April 2015

Allergy Research

Key words: Internalization, Der p2, human airway epithelium, Toll-like receptor 2, inflammation, calcitriol [more]

Papain Degrades Tight Junction Proteins of Human Keratinocytes In Vitro and Sensitizes C57BL/6 Mice via the Skin Independent of its Enzymatic Activity or TLR4 Activation

Caroline Stremnitzer, Krisztina Manzano-Szalai, Anna Willensdorfer, Philipp Starkl, Mario Pieper, Peter König, Michael Mildner, Erwin Tschachler, Ursula Reichart, Erika Jensen-Jarolim

Journal of Investigative Dermatology (Elsevier) Austria, Germany, 09 April 2015

Dermatology

Key words: Dermatophagoides pteronyssinus, transepidermal water loss, phosphate-buffered saline, Toll-like receptor 4 [more]

EBV Oncogene N-LMP1 Induces CD4 T Cell–Mediated Angiogenic Blockade in the Murine Tumor Model

The Journal of Immunology (American Association of Immunologists) China, 06 April 2015

Oncology

Key words: Antiangiogenic N-LMP1–specific T cell, Tumor single cells, In vivo angiogenesis assays [more]

Lung-specific loss of α3 laminin worsens bleomycin-induced pulmonary fibrosis

Luisa I Morales-Nebreda, Micah R Rogel, Jessica L Eisenberg, Kevin J Hamill, Saul Soberanes, Recep Nigdelioglu, Monica Chi, Takugo Cho, Kathryn A Radigan, Karen M Ridge, Alexander V Misharin, Alex Woychek, Susan Hopkinson, Harris Perlman, Gokhan M Mutlu, Annie Pardo, Moises Selman, Jonathan C R Jones, and G R Scott Budinger

American Journal of Respiratory Cell and Molecular Biology (ATS Journals) USA, Mexico, 01 April 2015

Pulmonology

Key words: laminin, matrix, pulmonary fibrosis, development [more]

Molecular characterization of whole mount prostate specimens using 5-color fluorescence labeling, virtual slide technology and automated image analysis

Georg E Steiner, Gwenaelle Gaillard, Karina Pfeil, Claudia Strele, Christine Linder, Vincent Laurain, Radu Rogojanu, Rupert C Ecker, Katja Oesterreicher, Lukas Kenner, Johannes Schmid, Helmut Klocker

Cancer Research (AACR Publications) Austria, 01 April 2015

Medical Image Analysis

Key words: Prostate tissue samples, tubular epithelial ducts, epithelial and non-epithelial cells

Chondroitin sulfate-polyethylenimine copolymer-coated superparamagnetic iron oxide nanoparticles as an efficient magneto-gene carrier for microRNA-encoding plasmid DNA delivery

YL Lo, HL Chou, ZX Liao, SJ Huang, JH Ke, YS Liu, CC Chiu, LF Wang

Nanoscale (Royal Society of Chemistry) Taiwan, 01 April 2015

Nanomedicine

Key words: Magnetofection, MicroRNA, Glioblastoma, Gene delivery [more]

nk4a/Arf-Dependent Loss of Parietal Cells Induced by Oxidative Stress Promotes CD44-Dependent Gastric Tumorigenesis

Ryo Seishima, Takeyuki Wada, Kenji Tsuchihashi, Shogo Okazaki, Momoko Yoshikawa, Hiroko Oshima, Masanobu Oshima, Toshiro Sato, Hirotoshi Hasegawa, Yuko Kitagawa, James R Goldenring, Hideyuki Saya, Osamu Nagano

Cancer Prevention Research (AACR Publications) Japan, USA, 26 March 2015

Oncology

Key words: Spasmolytic polypeptide–expressing metaplasia, reactive oxygen species, parietal cells [more]

Trained immunity in newborn infants of HBV-infected mothers

Michelle Hong, Elena Sandalova, Diana Low, Adam J Gehring, Stefania Fieni, Barbara Amadei, Simonetta Urbani, Yap-Seng Chong, Ernesto Guccione, Antonio Bertoletti

Nature Communications (Nature) Singapore, Italy, UK, 25 March 2015

Immunology, Virology

Key words: Calcium-sensing receptor, colon cancer, calcium, vitamin D, chemoprevention, calcimimetic [more]

Low-dose irradiation affects expression of inflammatory markers in the heart of ApoE-/-mice

Daniel Mathias, Ronald E J Mitchel, Mirela Barclay, Heather Wyatt, Michelle Bugden, Nicholas D Priest, Stewart C Whitman †, Markus Scholz, Guido Hildebrandt, Manja Kamprad, Annegret Glasow

PLoS One (PLOS) Germany, Canada, 23 March 2015

Cardiology

Key words: Collagens, Dosimetry, Inflammation , Fibrinogen , Blood plasma , Heart , White blood cells , Endothelial cells [more]

Reproductive Sciences

Reproductive Sciences (SAGE Journals) , 22 March 2015

Reproductive Medicine

Tissue Microarrays for Translational Research

Ronald Simon, Martina Mirlacher

Microarrays in Diagnostics and Biomarker Development (Springer) Germany, 19 March 2015

Biological Methods

Key words: Tissue microarray,

Cuprizone-induced demyelination and demyelination-associated inflammation result in different proton magnetic resonance metabolite spectra

Jelle Praet, Jasmien Orije, Firat Kara, Caroline Guglielmetti, Eva Santermans, Jasmijn Daans, Niel Hens, Marleen Verhoye, Zwi Berneman, Peter Ponsaerts, Annemie Van der Linden

NMR in Biomedicine (Wiley) Belgium, 19 March 2015

Oncology

Key words: GDF10/BMP3b, TGFBR3, oral cancer, prognostic marker, EMT, chemotherapy resistance [more]

CD20+ T cells have a predominantly Tc1 effector memory phenotype and are expanded in the ascites of patients with ovarian cancer

Marco de Bruyn, Valerie R Wiersma, Maartje C A Wouters, Douwe F Samplonius, Harry G Klip, Wijnand Helfrich, Hans W Nijman, Paul Eggletonc, Edwin Bremer

OncoImmunology (Taylor and Francis) The Netherlands, UK, Canada, 19 March 2015

Immunology

Key words: Ascites, cancer immunology, CD20, ovarian cancer, trogocytosis, APC, Antigen-Presenting Cell, CTL, Cytotoxic T Lymphocyte, FSC, Forward Scatter, OC, Ovarian Cancer, PBMC, Peripheral Blood Mononuclear Cell, SCC, Side Scatter, TC, Cytotoxic T cell, TCM, Central Memory T cell, TEM, Effector Memory T cell, TH, Helper T cell, TIL, Tumor Infiltrating T cell, TNaïve, Naïve T cell, Treg, Regulatory T cell, TTD, Terminally Differentiated T cell [more]

The calcium-sensing receptor suppresses epithelial-to-mesenchymal transition and stem cell- like phenotype in the colon

Abhishek Aggarwal, Maximilian Prinz-Wohlgenannt, Charlotte Gröschel, Samawansha Tennakoon, Anastasia Meshcheryakova, Wenhan Chang, Edward M Brown, Diana Mechtcheriakova, Enikö Kállay

Molecular Cancer (Springer) Austria, USA, 18 March 2015

Oncology

Key words: EVI1, MS4A3, transcriptional repression, myeloid leukemia, tumor growth [more]

MAP4K4 regulates integrin-FERM binding to control endothelial cell motility

Philip Vitorino, Stacey Yeung, Ailey Crow, Jesse Bakke, Tanya Smyczek, Kristina West, Erin McNamara, Jeffrey Eastham-Anderson, Stephen Gould, Seth F Harris, Chudi Ndubaku and Weilan Ye

Nature (Nature) USA, 18 March 2015

Cell Biology

Key words: Focal adhesion [more]

CARDIAC MAGNETIC RESONANCE T1 MAPPING FOR QUANTIFICATION OF EXTRACELLULAR MATRIX - VALIDATION BY MYOCARDIAL BIOPSY

Andreas Anselm Kammerlander, Caroline Tufaro, Alina Bachmann, Beatrice Marzluf, Stefan Aschauer, Andreas Greiser, Diana Bonderman, Julia Mascherbauer

Journal of the American College of Cardiology (Elsevier) Austria, 16 March 2015

Cardiology

Key words: Diffuse myocardial fibrosis, extracellular matrix expansion, cardiac magnetic resonance [more]

The Upregulation of LAG-3 on T Cells Defines a Subpopulation with Functional Exhaustion and Correlates with Disease Progression in HIV-Infected Subjects

The Journal of Immunology (American Association of Immunologists) China, 16 March 2015

Immunology, Virology

Key words: Plasmodium infection, virus–specific CD8+ T cells, human embryonic kidney cells [more]

Effect of 1,25-dihydroxyvitamin D3 on the Wnt pathway in non-malignant colonic cells

Charlotte Gröschel, Abhishek Aggarwal, Samawansha Tennakoon, Julia Höbaus, Maximilian Prinz-Wohlgenannt, Brigitte Marian, Petra Heffeter, Walter Berger, Eniko Kállay

The Journal of Steroid Biochemistry and Molecular Biology (Elsevier) Austria, 14 March 2015

Oncology

Key words: 1, 25-Dihydroxyvitamin D3, colorectal cancer, chemoprevention, wnt pathway, LGR5 [more]

Vimentin regulates activation of the NLRP3 inflammasome

Gimena dos Santos, Micah R Rogel, Margaret A Baker, James R Troken, Daniela Urich, Luisa Morales-Nebreda, Joseph A Sennello, Mikhail A Kutuzov, Albert Sitikov, Jennifer M Davis, Anna P Lam, Paul Cheresh, David Kamp, Dale K Shumaker, G R Scott Budinger and Karen M Ridge

Nature Communications (Nature) USA, 12 March 2015

Cell Biology

Key words: Cytoskeletal proteins, Inflammasome, NOD-like receptors, Respiratory tract diseases [more]

Nitric Oxide Prevents Alveolar Senescence and Emphysema in a Mouse Model

Amanda E Boe, Mesut Eren, Luisa Morales-Nebreda, Sheila B Murphy, G R Scott Budinger, Gökhan M Mutlu, Toshio Miyata, Douglas E Vaughan

PLoS One (PLOS) USA, Japan, 10 March 2015

Pulmonology

Key words: Nω-nitro-L-arginine methyl ester, alveolar tissue destruction, plasminogen activator inhibitor-1 [more]

Clinical improvement in psoriasis with specific targeting of interleukin-23

Tamara Kopp, Elisabeth Riedl, Christine Bangert, Edward P Bowman, Elli Greisenegger, Ann Horowitz, Harald Kittler, Wendy M Blumenschein, Terrill K McClanahan, Thomas Marbury, Claus Zachariae, Danlin Xu, Xiaoli Shirley Hou, Anish Mehta, Anthe S Zandvliet, Diana Montgomery, Frank van Aarle and Sauzanne Khalilieh

Nature (Nature) Austria, USA, Denmark, 09 March 2015

Dermatology

Key words: Psoriasis, interleukin-23 [more]

Induction of c-Cbl contributes to anti-cancer effects of HDAC inhibitor in lung cancer

TT Wei, YC Lin, PH Lin, JY Shih, CW Chou, WJ Huang, YC Yang, PW Hsiao, CC Chen

Oncotarget (Impact Journals) Taiwan, 08 March 2015

Oncology

Key words: c-Cbl, EGFR, HDAC inhibitors, lung cancer [more]

Active vitamin D potentiates the anti-neoplastic effects of calcium in the colon: A cross talk through the calcium-sensing receptor

Abhishek Aggarwal, Julia Höbaus, Samawansha Tennakoon, Maximilian Prinz-Wohlgenannt, João Graça, Sally A Price, Petra Heffeter, Walter Berger, Sabina Baumgartner-Parzer, Enikö Kállay

The Journal of Steroid Biochemistry and Molecular Biology (Elsevier) Austria, UK, 07 March 2015

Oncology

Key words: Calcium-sensing receptor, Colon cancer, Calcium, Vitamin D, Chemoprevention, Calcimimetic [more]

Zileuton, 5-Lipoxygenase Inhibitor, Acts as a Chemopreventive Agent in Intestinal Polyposis, by Modulating Polyp and Systemic Inflammation

Elias Gounaris, Michael J Heiferman, Jeffrey R Heiferman, Manisha Shrivastav, Dominic Vitello, Nichole R Blatner, Lawrence M Knab, Joseph D Phillips, Eric C Cheon, Paul J Grippo, Khashayarsha Khazaie, Hidayatullah G Munshi, David J Bentrem

PLoS One (PLOS) USA, 06 March 2015

Oncology

Key words: Calcium-sensing receptor, tumor suppressor, colorectal cancer, colon, calcium, calcimimetic, calcilytic [more]

Disruption of ​STAT3 signalling promotes ​KRAS-induced lung tumorigenesis

Beatrice Grabner, Daniel Schramek, Kristina M Mueller, Herwig P Moll, Jasmin Svinka, Thomas Hoffmann, Eva Bauer, Leander Blaas, Natascha Hruschka, Katalin Zboray, Patricia Stiedl, Harini Nivarthi, Edith Bogner, Wolfgang Gruber, Thomas Mohr, Ralf Harun Zwick, Lukas Kenner, Valeria Poli, Fritz Aberger, Dagmar Stoiber, Gerda Egger, Harald Esterbauer, Johannes Zuber, Richard Moriggl, Robert Eferl, Balázs Gy?rffy, Josef M Penninger, Helmut Popper ,Emilio Casanova

Nature Communications (Nature) Austria, USA, Italy, Hungary, 03 March 2015

Oncology

Key words: Interleukin-6, oncostatin-M, epidermal growth factor, Lung cancer [more]

16 Dectin-2 is essentially involved in innate immune response of experimental arthritis

V Stögner, T Shvets, B Niederreiter, M Koenders, WB van den Berg, JS Smolen, K Redlich, S Hayer

Annals of the Rheumatic Diseases (BMJ Journals) Austria, The Netherlands, 01 March 2015

Rheumatology

Key words: C-type lectin receptor Dectin-2, Toll-like receptors, myeloid cells [more]

Comparative Proteomic Analysis Reveals Activation of Mucosal Innate Immune Signaling Pathways during Cholera

Crystal N Ellis, Regina C LaRocquea, Taher Uddin, Bryan Krastins, Leslie M Mayo-Smith, David Sarracino, Elinor K Karlsson, Atiqur Rahman, Tahmina Shirin, Taufiqur R Bhuiyan, Fahima Chowdhury, Ashraful Islam Khan, Edward T Ryan, Stephen B Calderwood, Firdausi Qadri, Jason B Harris

Infection and Immunity (ASM) USA, Bangladesh, 01 March 2015

Immunology

Key words: Tissue microarray, Tissue cores, Population studies, Virtual microscopy, Data exchange, Standards Validation studies, Quality assurance, Donor block, Recipient block, Multitumo, r Tissue microarray, Progression tissue microarray, Prognosis tissue microarray, Normal tissue microarray, Frozen tissue microarray, Cell line tissue microarray, Xenograft tissue microarray, Cutting edge matrix assembly tissue microarray, Immunohistochemistry , Chromogenic in situ hybridization (CISH), Fluorescent in situ hybridization (FISH), Quantum dots, Multiplex immunoblotting, Hierarchical clustering analysis, Hierarchical naïve, Bayes model, Random forest clustering [more]

EVI1 promotes tumor growth via transcriptional repression of MS4A3

Gerwin Heller, Anna Rommer, Katarina Steinleitner, Julia Etzler, Hubert Hackl, Petra Heffeter, Erwin Tomasich, Martin Filipits, Birgit Steinmetz, Thais Topakian, Simone Klingenbrunner, Barbara Ziegler, Andreas Spittler, Sabine Zöchbauer-Müller, Walter Berger, Rotraud Wieser

Journal of Hematology & Oncology (Springer) Austria, 01 March 2015

Oncology

Key words: EVI1, MS4A3, Transcriptional repression, Myeloid leukemia, Tumor growth [more]

Loss of GDF10/BMP3b as a prognostic marker collaborates with TGFBR3 to enhance chemotherapy resistance and epithelial-mesenchymal transition in oral squamous cell carcinoma

Chieh-Wen Cheng, Jenn-Ren Hsiao, Chi-Chen Fan, Yu-Kang Lo, Chi-Yuan Tzen, Li-Wha Wu, Wei-Yu Fang, Ann-Joy Cheng, Chung-Hsing Chen, I-Shou Chang, Shih Sheng Jiang, Jang-Yang Chang, Alan Yueh-Luen Lee

Molecular Carcinogenesis (Wiley) Taiwan, 01 March 2015

Oncology

Key words: Growth differentiation factor-10, transforming growth factor-β (TGF-β) superfamily, oral squamous cell carcinoma [more]

Poly(lactide-co-glycolide) microspheres for MRI-monitored delivery of sorafenib in a rabbit VX2 model

Jeane Chena, Sarah B White, Kathleen R Harris, Weiguo Li, Jonathan WT Yap, Dong-Hyun Kim, Robert J Lewandowski, Lonnie D Shea, Andrew C Larson

Biomaterials (Elsevier) USA, 25 February 2015

Nanomedicine

Key words: Sorafenib, hepatocellular carcinoma, poly(lactide-co-glycolide), magnetic resonance imaging [more]

Regulatory T cell-deficient scurfy mice develop systemic autoimmune features resembling lupus-like disease

Eva N Hadaschik, Xiaoying Wei, Harald Leiss, Britta Heckmann, Birgit Niederreiter, Günter Steiner, Walter Ulrich, Alexander H Enk, Josef S Smolen, Georg H Stummvoll

Arthritis Research and Therapy (BioMed Central) Germany, China, Austria, 23 February 2015

Rheumatology

Key words: Systemic lupus erythematosus, severe interface dermatitis, arthritis, mesangioproliferative glomerulonephritis [more]

The calcium-sensing receptor: A promising target for prevention of colorectal cancer

Abhishek Aggarwal, Maximilian Prinz-Wohlgenannt, Samawansha Tennakoona, Julia Höbaus, Cedric Boudot, Romuald Mentaverri, Edward M Brown, Sabina Baumgartner-Parzer, Enikö Kállay

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (Elsevier) Austria, France, USA, 18 February 2015

Oncology

Key words: Calcium-sensing receptor, tumor suppressor, colorectal cancer, colon, calcium, calcimimetic, calcilytic [more]

MRI visible drug eluting magnetic microspheres for transcatheter intra-arterial delivery to liver tumors

DH Kim, J Chen, RA Omary, AC Larson

Theranostics (NCBI) USA, 07 February 2015

Oncology, Nanomedicine

Key words: MRI, microspheres, liver tumors [more]

Tissue Microarray

Myra L Wilkerson, Stephen M Hewitt

Handbook of Practical Immunohistochemistry (Springer) USA, 05 February 2015

Biological Methods

Key words: Tissue microarray, tissue cores, population studies, virtual microscopy, data exchange, standards, validation studies, quality assurance, donor block, recipient block, multitumor, tissue microarray, progression tissue microarray, prognosis tissue microarray, normal tissue microarray, frozen tissue microarray, cell line tissue microarray, xenograft tissue microarray, cutting edge matrix assembly tissue microarray, immunohistochemistry, chromogenic in situ hybridization (CISH), fluorescent in situ hybridization (FISH), quantum dots, multiplex immunoblotting, hierarchical clustering analysis, hierarchical naïve Bayes model, random forest clustering

Generation of an anti-EpCAM antibody and epigenetic regulation of EpCAM in colorectal cancer

Mei-Ying Liao, Mark Yen-Ping Kuo, Tung-Ying Lu, Yi-Ping Wang, Han-Chung Wu

International Journal of Oncology (Spandidos Publications) Taiwan, 05 February 2015

Oncology

Key words: epigenetic regulation, EpCAM, colorectal cancer [more]

Extracellular matrix expansion by cardiac magnetic resonance T1 mapping- validation with myocardial biopsy

Andreas Kammerlander, Caroline Tufaro, Alina F Bachmann, Beatrice A Marzluf, Stefan Aschauer, Andreas Greiser, Diana Bonderman, Julia Mascherbauer

Journal of Cardiovascular Magnetic Resonance (Springer) Austria, Germany, 03 February 2015

Cardiology

Key words: Cardiology, angiology, imaging/radiology [more]

Distinct in vitro properties of embryonic and extraembryonic fibroblast-like cells are reflected in their in vivo behavior following grafting in the adult mouse brain

Costa R, Bergwerf I, Santermans E, De Vocht N, Praet J, Daans J, Le Blon D, Hoornaert C, Reekmans K, Hens N, Goossens H, Berneman Z, Parolini O, Alviano F, Ponsaerts P

Cell Transplantation (SAGE Journals) Italy, 01 February 2015

Transplantation Medicine

Key words: Fetal membrane-derived stromal cells, Embryonic fibroblasts, Immunomodulation, Transplantation, Brain, Angiogenesis [more]

The expression of thymic stromal lymphopoietin in primary tumors of breast cancer is associated with prognosis

Yu H, Yang J, Li Y, Jiao S

Chinese journal of cellular and molecular immunology (NCBI) China, 01 February 2015

Oncology

Key words: Rythymic stromal lymphopoietin, disease-free survival, Univariate LOG-RANK [more]

Biomarkers in Lung Diseaes: from Pathogenesis to Prediction to New Therapies: A-kinase-anchoring proteins coordinate inflammatory responses to cigarette smoke in airway smooth muscle

Wilfred J Poppinga, Irene H Heijink, Laura J Holtzer, Philipp Skroblin, Enno Klussmann, Andrew J Halayko, Wim Timens, Harm Maarsingh, Martina Schmidt

American Journal of Physiology (APS Journals) The Netherlands, Germany, Canada, USA, 30 January 2015

Pulmonology

Key words: Compartmentalization, A-kinase-anchoring protein, inflammation, cyclic AMP, chronic obstructive pulmonary disease [more]

The Major Birch Pollen Allergen Bet v 1 Induces Different Responses in Dendritic Cells of Birch Pollen Allergic and Healthy Individuals

Ursula Smole, Christian Radauer, Nina Lengger, Martin Svoboda, Neil Rigby, Merima Bublin, Sonja Gaier, Karin Hoffmann-Sommergruber, Erika Jensen-Jarolim, Diana Mechtcheriakova , Heimo Breiteneder

PLoS One (PLOS) USA, Austria, UK, 30 January 2015

Allergy Research

Key words: Allergens, cytokines, gene expression, pollen, immune response, fluorescence competition, monocytes, chemokines [more]

Correlation of circular RNA abundance with proliferation–exemplified with colorectal and ovarian cancer, idiopathic lung fibrosis, and normal human tissues

Anna Bachmayr-Heyda, Agnes T Reiner, Katharina Auer, Nyamdelger Sukhbaatar, Stefanie Aust, Thomas Bachleitner-Hofmann, Ildiko Mesteri, Thomas W Grunt, Robert Zeillinger and Dietmar Pils

Scientific Reports (Nature) Austria, 27 January 2015

Oncology

Key words: Cancer genetics, Epigenetics [more]

Mapping spatial heterogeneity in the tumor microenvironment: a new era for digital pathology

Andreas Heindl, Sidra Nawaz, Yinyin Yuan

Nature (Nature) UK, 19 January 2015

Oncology

Key words: Tumor, digital pathology, mapping, spatial heterogeneity

Loss of mitochondrial exo/endonuclease EXOG affects mitochondrial respiration and induces ROS-mediated cardiomyocyte hypertrophy

Wardit Tigchelaar, Hongjuan Yu, Anne Margreet de Jong, Wiek H van Gilst, Pim van der Harst, B Daan Westenbrink, Rudolf A de Boer, Herman H W Silljé

Cell Physiology (APS Journals) The Netherlands, China, 15 January 2015

Cardiology

Key words: Cardiomyocytes, hypertrophy, mitochondria, mitochondrial respiration, ROS [more]

Down-regulation of TIMP-1 inhibits cell migration, invasion, and metastatic colonization in lung adenocarcinoma

Ying-Hua Chang, Yi-Jen Chiu, Hung-Chi Cheng, Fang-Ju Liu, Wu-Wei Lai, Hsiao-Jen Chang, Pao-Chi Liao

Tumor Biology (Springer) Taiwan, USA, 13 January 2015

Oncology

Key words: TIMP-1, migration, invasion, metastatic colonization, pericellular fibronectin assembly, lung adenocarcinoma [more]

Localization of sunitinib, its metabolites and its target receptors in tumour-bearing mice: a MALDI-MS imaging study

S Torok, A Vegvari, M Rezeli, T E Fehniger, J Tovari, S Paku, V Laszlo, B Hegedus, A Rozsas, B Dome, G Marko-Varga

British Journal of Pharmacology (Wiley) Hungary, Austria, Sweden, Japan, 12 January 2015

Pharmacology

Key words: C-26 adenocarcinoma cells, matrix-assisted laser desorption ionization MS imaging, VEGF receptor-2 [more]

Epitope topography controls bioactivity in supramolecular nanofibers

S Sur, F Tantakitti, JB Matson, SI Stupp

Biomaterials Science (Royal Society of Chemistry) USA, 09 January 2015

Nanomedicine

Key words: Epitope topography, bioactivity, nanofibers [more]

A multidisciplinary approach unravels early and persistent effects of X-ray exposure at the onset of prenatal neurogenesis

Tine Verreet, Roel Quintens, Debby Van Dam, Mieke Verslegers, Mirella Tanori, Arianna Casciati, Mieke Neefs, Liselotte Leysen, Arlette Michaux, Ann Janssen, Emiliano D’Agostino, Greetje Vande Velde, Sarah Baatout, Lieve Moons, Simonetta Pazzaglia, Anna Saran, Uwe Himmelreich, Peter Paul De Deyn, Mohammed Abderrafi Benotmane

Journal of Neurodevelopmental Disorders (Springer) Belgium, Italy, The Netherlands, 09 January 2015

Neuroscience

Key words: Apoptosis, Brain development, Cognitive dysfunction, MRI, Radiation [more]

SMAD2 and p38 signaling pathways act in concert to determine XY primordial germ cell fate in mice

Q Wu, K Fukuda, M Weinstein, JM Graff, Y Saga

Development (The Company of Biologists) Japan, USA, 01 January 2015

Developmental Biology

Key words: sex determination, Meiosis, SMAD2 signaling, p38 signaling, Nanos2, Smad2/3 conditional knockout mice [more]

Zinc and pioglitazone effects on ovaries and endometrium in diabetes

C Gales, C Zamfir, B Stoica, M Nechifor

Farmacia () Romania, 01 January 2015

Reproductive Medicine

Key words: diabetes, zinc, pioglitazone, endometrium [more]

Relationship between Apoptosis Imaging and Radioiodine Therapy in Tumor Cells with Different Sodium Iodide Symporter Gene Expression

Kyung Oh Jung, Hyewon Youn, Young-Hwa Kim, Seunghoo Kim, Juri Na, Yong-Il Kim, Jin Woo Park, Keon Wook Kang, Dong Soo Lee, June-Key Chung

Molecular Imaging (SAGE Journals) South Korea, 01 January 2015

Oncology

Key words: Apoptosis Imaging, Radioiodine Therapy, Tumor Cells, Sodium Iodide Symporter [more]

Comparative assessment of biocompatibility of NiCr and CoCr alloys used in metalfused-to-ceramic technology

RALUCA MONICA COMANEANU, VIOLETA HANCU, HORIA MIHAIL BARBU, COSTIN COMAN, COSMIN MIHAI COTRUT, MIHAIL TARCOLEA, ANA MARIA HOLICOV, ALINA ORMENISAN

REVISTA DE CHIMIE () Romania, 01 January 2015

Biological Methods

Key words: NiCr and CoCr alloys, metal-fused-to-ceramic restoration, biomaterial, biocompatibility [more]

MRI-Monitored Intra-Tumoral Injection of Iron-Oxide Labeled Clostridium novyi-NT Anaerobes in Pancreatic Carcinoma Mouse Model

Linfeng Zheng, Zhuoli Zhang, Khashayarsha Khazaie, Saurabh Saha, Robert J Lewandowski, Guixiang Zhang, Andrew C Larson

PLoS One (PLOS) USA, China, 30 December 2014

Oncology

Key words: Magnetic resonance imaging, catheters, anaerobic bacteria, gram staining, fluorescence microscopy, transmission electron microscopy, in vivo imaging, nanoparticles [more]

Coronary Neutrophil Extracellular Trap Burden and Deoxyribonuclease Activity in ST-Elevation Acute Coronary Syndrome Are Predictors of ST-Segment Resolution and Infarct Size

Andreas Mangold, Sherin Alias, Thomas Scherz, Thomas Hofbauer, Johannes Jakowitsch, Adelheid Panzenböck, Daniel Simon, Daniela Laimer, Christine Bangert, Andreas Kammerlander, Julia Mascherbauer, Max-Paul Winter, Klaus Distelmaier, Christopher Adlbrecht, Klaus T Preissner, Irene M Lang

Circulation Research (AHA Journals) Germany, Austria, 29 December 2014

Cardiology

Key words: Atherosclerosis, coronary occlusion, coronary thrombosis, deoxyribonucleases, extracellular traps, myocardial infarction, neutrophils [more]

PIAS1 is a crucial factor for prostate cancer cell survival and a valid target in docetaxel resistant cells

Martin Puhr, Julia Hoefer, Hannes Neuwirt, Iris E Eder, Johann Kern, Georg Schäfer, Stephan Geley, Isabel Heidegger, Helmut Klocker, Zoran Culig

Oncotarget (Impact Journals) Austria, 24 December 2014

Oncology

Key words: prostate cancer, PIAS1, docetaxel, chemotherapy resistance, apoptosis [more]

TLR4-mediated inflammation promotes foam cell formation of vascular smooth muscle cell by upregulating ACAT1 expression

Y-W Yin, S-Q Liao, M-J Zhang, Y Liu, B-H Li, Y Zhou, L Chen, C-Y Gao, J-C Li and L-L Zhang

Cell Death & Disease (Nature) China, 18 December 2014

Cardiology

Key words: Atherosclerosis, Cell signalling, Foam cells, Inflammation [more]

Epidermal Elafin Expression Is an Indicator of Poor Prognosis in Cutaneous Graft-versus-Host Disease

Marie-Charlotte Brüggen, Peter Petzelbauer, Hildegard Greinix, Emmanuel Contassot, Dragana Jankovic, Lars French, Gérard Socié, Werner Rabitsch, Zoya Kuzmina, Peter Kalhs, Robert Knobler, Georg Stingl, Georg Stary

Journal of Investigative Dermatology (Elsevier) Austria, Switzerland, France, 18 December 2014

Dermatology

Key words: Epidermal elafin, cutaneous graft, host disease [more]

The cognitive defects of neonatally irradiated mice are accompanied by changed synaptic plasticity, adult neurogenesis and neuroinflammation

Stefan J Kempf, Arianna Casciati, Sonja Buratovic, Dirk Janik, Christine von Toerne, Marius Ueffing, Frauke Neff, Simone Moertl, Bo Stenerlöw, Anna Saran, Michael J Atkinson, Per Eriksson, Simonetta Pazzaglia, Soile Tapio

Molecular Neurodegeneration (BioMed Central) Germany, Italy, Sweden, 16 December 2014

Neuroscience

Key words: Dendritic spines, hippocampus, cortex, CREB, miR-132, ionising radiation, proteomics, Rac1, cofilin, alzheimer [more]

Quantitative measurement of cancer tissue biomarkers in the lab and in the clinic

Daniel E Carvajal-Hausdorf, Kurt A Schalper, Veronique M Neumeister and David L Rimm

Laboratory Investigation (Nature) USA, 15 December 2014

Oncology

Key words: Breast cancer

Carboxylated Short Single-Walled Carbon Nanotubes But Not Plain and Multi-Walled Short Carbon Nanotubes Show in vitro Genotoxicity

Maria Mrakovcic, Claudia Meindl, Gerd Leitinger, Eva Roblegg, Eleonore Fröhlich

Toxicological Sciences (Oxford University Press) Austria, 10 December 2014

Toxicology

Key words: Carbon nanotubes, cytotoxicity, genotoxicity, oxidative stress, HPRT mutation, assay micronucleus [more]

Pharmacodynamic and Therapeutic Investigation of Focused Ultrasound-Induced Blood-Brain Barrier Opening for Enhanced Temozolomide Delivery in Glioma Treatment

Hao-Li Liu, Chiung-Yin Huang, Ju-Yu Chen, Hay-Yan Jack Wang, Pin-Yuan Chen, Kuo-Chen Wei

PLoS One (PLOS) Taiwan, 09 December 2014

Oncology

Key words: Cancer treatment, magnetic resonance imaging, glioma, drug therapy, pharmacodynamics, blood plasma, liquid chromatography-mass spectrometry, glioma cells [more]

Effects of azithromycin and tanomastat on experimental bronchiolitis obliterans

Katharina Krenn, Matthias Gmeiner, Patrick Paulus, Nezir Sela, Linda Torres, Karin Zins, Gerhard Dekan, Seyedhossein Aharinejad

The Journal of thoracic and cardiovascular surgery (Elsevier) Austria, Germany, 04 December 2014

Pulmonology

Key words: Azithromycin, tanomastat [more]

Clec4n Is Essentially Involved in Innate Immune Response of Experimental Arthritis

V Stögner, T Shvets, B Niederreiter, M Koenders, W van den Berg,J Smolen, K Redlich, S Hayer

Rehabilitation () The Netherlands, 04 December 2014

Rheumatology

TonEBP/NFAT5 regulates ACTBL2 expression in biomechanically activated vascular smooth muscle cells

M Hödebeck, C Scherer, AH Wagner, M Hecker, T Korff

Frontiers in Physiology (Frontiers Media S.A.) Germany, 03 December 2014

Physiology

[more]

Selective delivery of IFN-γ to renal interstitial myofibroblasts: a novel strategy for the treatment of renal fibrosis

Fariba Poosti, Ruchi Bansal, Saleh Yazdani, Jai Prakash, Eduard Post, Pieter Klok, Jacob van den Born, Martin H de Borst, Harry van Goor, Klaas Poelstra, Jan-Luuk Hillebrands

The FASEB Journal (FASEB) The Netherlands, 02 December 2014

Nephrology

Key words: Drug targeting, PDGFRβ, kidney, unilateral ureteral obstruction [more]

Prognostic Significance and Determinants of the 6-minute Walk Test in Patients with Pulmonary Hypertension Associated with Heart Failure and Preserved Ejection Fraction

C Tufaro, J Mascherbauer, F Duca, S Aschauer, A Panzenboeck, C Bangert, D Laimer, I Lang, D Bonderman

Pneumologie (Thieme) Austria, 01 December 2014

Pulmonology

Key words: Exertional fatigue, dyspnea, pulmonary hypertension, heart failure with preserved ejection fraction

Stat5 gene dosage in T cells modulates CD8+ T-cell homeostasis and attenuates contact hypersensitivity response in mice

H Nivarthi, M Prchal-Murphy, A Swoboda, M Hager, M Schlederer, L Kenner, J Tuckermann, V Sexl, R Moriggl, O Ermakova

Allergy (Wiley) Austria, Germany, Italy, 30 November 2014

Allergy Research

Key words: Allergic contact dermatitis, Stat5, T cells [more]

Protection of Shengmai Recipe on Improving Cardiac Function and Attenuating Kidney Injury in Pressure Overload Rats

Feng-jiao Sun, Peng-wei Zhuang, Yu Wang, Jin-bao Zhang, Zhi-qiang Lu, Yan Wang, Mi-xia Zhang, Jin Wu, Zhuo Chen, Meng Sun, Yan-jun Zhang

Chinese Herbal Medicines (Elsevier) China, 27 November 2014

Cardiology

Key words: Chronic heart failure, left ventricular systolic function, myocardial fibrosis, renal ischemia lesion, Shengmai Recipe [more]

A subset of chondrogenic cells provides early mesenchymal progenitors in growing bones

N Ono, W Ono, T Nagasawa, HM Kronenberg

Nature Cell Biology (Nature) USA, Japan, 24 November 2014

Stem Cell Research

Key words: Bone development, Mesenchymal stem cells [more]

CD16+ monocytes with smooth muscle cell characteristics are reduced in human renal chronic transplant dysfunction

M Boersema, JC van den Born, J van Ark, G Harms, MA Seelen, MCRF van Dijk, H van Goor, GJ Navis, ER Popa, JL Hillebrands

Immunobiology (Elsevier) The Netherlands, 21 November 2014

Immunology

Key words: Chronic transplant dysfunction, Kidney, Monocytes, Monocyte heterogeneity, Smooth-muscle-like cells, Transplantation [more]

CD16⁺ monocytes with smooth muscle cell characteristics are reduced in human renal chronic transplant dysfunction.

M Boersema, J van Ark, MA Seelen, MCRF van Dijk, H van Goor, GJ navis, ER Popa, JL Hillebrands

Immunobiology (Elsevier) The Netherlands, 21 November 2014

Transplantation Medicine

Key words: Chronic transplant dysfunction, Kidney, Monocytes, Monocyte heterogeneity, Smooth-muscle-like cells, Transplantation [more]

Hepatic stellate cells secretes type I collagen to trigger epithelial mesenchymal transition of hepatoma cells

MC Yang, CJ Wang, PC Liao, CJ Yen, YS Shan

American Journal of Cancer Research (NCBI) China, Taiwan, 19 November 2014

Oncology

Key words: Hepatic stellate cell, collagen type I, epithelial-mesenchymal transition [more]

Comparison of CD163+ macrophages and CD206+ cells in lesional skin of CD30+ lymphoproliferative disorders of lymphomatoid papulosis and primary cutaneous anaplastic large-cell lymphoma

Aya Kakizaki, Taku Fujimura, Yumi Kambayashi, Sadanori Furudate, Mitsuko Kawano, Kouetsu Ogasawara, Setsuya Aiba

Acta Dermato Venereologica (Ingentaconnect) Japan, 18 November 2014

Dermatology

Key words: CD163+ Macrophages, CD206+ Cells, Skin Lesion, CD30+ LymphoproliferativeDisorders, Lymphomatoid Papulosis, Primary Cutaneous Anaplastic Large-cell Lymphoma [more]

Effect of preemptive treatment with human umbilical cord blood-derived mesenchymal stem cells on the development of renal ischemia-reperfusion injury in mice

Hye Ryoun Jang, Ji Hyeon Park, Ghee Young Kwon, Jung Eun Lee, Wooseong Huh, Hye Jin Jin, Soo Jin Choi, Wonil Oh, Ha Young Oh, Yoon-Goo Kim

American Journal of Physiology (APS Journals) South Korea, 15 November 2014

Nephrology

Key words: Mesenchymal stem cells, inflammation, renal ischemia-reperfusion injury, human umbilical cord blood-derived mesenchymal stem cells [more]

Generation of induced pluripotent stem cells without genetic defects by small molecules

Hang-Soo Parka, Insik Hwanga, Kyung-Ah Choia, Hyesun Jeonga, Ji-Yun Leeb, Sunghoi Hong

Biomaterials (Elsevier) South Korea, 15 November 2014

Biological Materials

Key words: Induced pluripotent stem cells, small molecules, genomic stability, DNA double-strand breaks [more]

An increase in integrin-linked kinase non-canonically confers NF-κB-mediated growth advantages to gastric cancer cells by activating ERK1/2

Po-Chun Tseng, Chia-Ling Chen, Yan-Shen Shan, Wen-Teng Chang, Hsiao-Sheng Liu, Tse-Ming Hong, Chia-Yuan Hsieh, Sheng-Hsiang Lin, Chiou-Feng Lin

Cell Communication and Signaling (Springer) Taiwan, 15 November 2014

Oncology

Key words: ILK, Cell growth, IQGAP1, ERK1/2, NK-κB [more]

No evidence of cell cycle dysregulation in mantle cell lymphoma in vivo

Niklas Vogt, Dmitriy Abramov, Karoline Koch, Neus Masqué-Soler, Monika Szczepanowski, and Wolfram Klapper

Leukemia and Lymphoma (Informa) Germany, Russia, 14 November 2014

Oncology

Key words: Mantle cell lymphoma, cyclin D1, Ki67, cell cycle, immunofluorescence [more]

The Patched 1 Tumor-Suppressor Gene Protects the Mouse Lens from Spontaneous and Radiation-Induced Cataract

Ilaria De Stefano, Barbara Tanno, Paola Giardullo, Simona Leonardi, Emanuela Pasquali, Francesca Antonelli, Mirella Tanori, Arianna Casciati, Simonetta Pazzaglia, Anna Saran, Mariateresa Mancuso

The American Journal of Pathology (Elsevier) Italy, 14 November 2014

Cell Biology

Key words: Epithelial-to-mesenchymal transition, lens epithelial cells, growth factor β, medulloblastoma, Gorlin syndrome [more]

Characterization and anti-tumor effects of chondroitin sulfate–chitosan nanoparticles delivery system

Chieh-Shen Hu, Sung-Ling Tang, Chiao-Hsi Chiang, Hossein Hosseinkhani, Po-Da Hong, Ming-Kung Yeh

Journal of Nanoparticle Research (Springer) Taiwan, 07 November 2014

Oncology

Key words: Cell uptake efficiency, hepg2 cell, dox concentration, chondroitin sulfate, encapsulation efficiency, chitosan nanoparticle, anthracycline, gold nanoparticle, disaccharide, hepg2 cell line, entrapment efficiency, tumor volume [more]

The Pseudomonas aeruginosa type III translocon is required for biofilm formation at the epithelial barrier

Cindy S Tran, Stephanie M Rangel, Henrik Almblad, Arlinet Kierbel, Michael Givskov, Tim Tolker-Nielsen, Alan R Hauser, Joanne N Engel

PLoS Pathogens (PLOS) Uruguay, Singapore, Denmark, USA, 06 November 2014

Microbiology

Key words: Bacterial biofilms, Pseudomonas aeruginosa, Pulmonary imaging, Antibiotic resistance, Host cells Cell staining, Confocal microscopy, Mouse models [more]

Pharmacological inhibition of TGFβ receptor improves Nkx2.5 cardiomyoblast-mediated regeneration

Wen-Pin Chen, Yuan-Hung Liu, Yi-Jin Ho, Sean M Wu

Cardiovascular Research (Oxford University Press) Taiwan, USA, 01 November 2014

Regenerative Medicine

Key words: Nkx2.5, Cardiomyoblast, TGFβ, Regeneration, Myocardial infarction [more]

GATA2 Regulates Differentiation Of Bone Marrow-Derived Mesenchymal Stem Cells

Mayumi Kamata, Yoko Okitsu, Tohru Fujiwara, Masahiko Kanehira, Shinji Nakajima, Taro Takahashi, Ai Inoue, Noriko Fukuhara, Yasushi Onishi, Kenichi Ishizawa, Ritsuko Shimizu, Masayuki Yamamoto, Hideo Harigae

Haematologica (Ferrata Storti Foundation) Japan, 01 November 2014

Stem Cell Research

Key words: Bone marrow, stem cells [more]

The role of cytokines and chemokines in the T-cell-mediated autoimmune process in alopecia areata

Taisuke Ito, Yoshiki Tokura

Experimental Dermatology (Wiley) Japan, 29 October 2014

Dermatology

Key words: Alopecia areata, chemokine, cytokine, immune privilege, swarm of bees [more]

Megakaryocytes are essential for HSC quiescence through the production of thrombopoietin

Ayako Nakamura-Ishizua, Keiyo Takubo, Masato Fujioka, Toshio Suda

Biochemical and Biophysical Research Communications (Elsevier) Japan, 24 October 2014

Hematology

Key words: Megakaryocytes, hematopoietic stem cells, thrombopoietin, niche, bone marrow [more]

Fenretinide: A Novel Treatment for Endometrial Cancer

Navdha Mittal, Saurabh Malpani, Matthew Dyson, Masanori Ono, John S Coon, Julie J Kim, Julian C Schink, Serdar E Bulun, Mary Ellen Pavone

PLoS One (PLOS) USA, 23 October 2014

Oncology

Key words: Cancer treatment, apoptosis, uterine cancer, vitamin A, gene expression, small interfering RNAs, retinoic acid, cancer therapy [more]

Loss of Gsα Early in the Osteoblast Lineage Favors Adipogenic Differentiation of Mesenchymal Progenitors and Committed Osteoblast Precursors

Partha Sinha, Piia Aarnisalo, Rhiannon Chubb, Noriaki Ono, Keertik Fulzele, Martin Selig, Hamid Saeed, Min Chen, Lee S Weinstein, Paola Divieti Pajevic, Henry M Kronenberg, Joy Y Wu

Journal of Bone and Mineral Research (Wiley) USA, Finland, 20 October 2014

Rheumatology

Key words: Osteoblasts, GSA, mesenchymal progenitors, adipocytes [more]

Role of fractalkine in the pathogenesis of primary Sjögren syndrome: increased serum levels of fractalkine, its expression in labial salivary glands, and the association with clinical manifestations

Jae Ho Lee, Seung-Ki Kwok, Seung Min Jung, Jennifer Lee, Jae-Seon Lee, Seung Ye Baek, Eun-Kyung Kim, Ji Hyeon Ju, Sung-Hwan Park and Ho-Youn Kim

Journal of Rheumatology (jrheum.org) South Korea, 15 October 2014

Rheumatology

Key words: SJÖGREN SYNDROME, FRACTALKINE, CX3CR1 [more]

Langerhans cells promote early germinal center formation in response to Leishmania-derived cutaneous antigens

Nicole Zimara, Christian Florian, Maximilian Schmid, Bernard Malissen, Adrien Kissenpfennig, Daniela N Männel, Matthias Edinger, James A Hutchinson, Petra Hoffmann, Uwe Ritter

European Journal of Immunology (Wiley) Germany, France, UK, 13 October 2014

Immunology

Key words: B cells, follicular helper, germinal center reaction, langerhans cells, leishmania major, T cells [more]

The pre- and post-somatic segments of the human type I spiral ganglion neurons – Structural and functional considerations related to cochlear implantation

W Liu, F Edin, F Atturo, G Rieger, H Löwenheime, P Senn, M Blumer, A Schrott-Fischer, H Rask-Andersen, R Glueckert

Neuroscience (Elsevier) Sweden, Italy, Austria, Germany, Switzerland, 12 October 2014

Neuroscience

Key words: Human cochlea, spiral ganglion neurons, non-myelinated Schwann cells, laminin-ß2, collagen IV, immunohistochemistry [more]

Specific expression of OATPs in primary small cell lung cancer (SCLC) cells as novel biomarkers for diagnosis and therapy

Stefan Brenner, Lukas Klameth, d, Juliane Riha, Madeleine Schölm, Gerhard Hamilton, Erika Bajna, Christoph Ausch, Angelika Reiner, Walter Jäger, Theresia Thalhammer , Veronika Buxhofer-Ausch

Cancer Letters (Elsevier) Austria, 06 October 2014

Oncology

Key words: Small cell lung cancer (SCLC), organic anion transporting polypeptide (OATP), neurogenic marker, chemotherapy, OATP gene expression [more]

TGF-β is an inducer of ZEB1-dependent mesenchymal transdifferentiation in glioblastoma that is associated with tumor invasion

JV Joseph, S Conroy, T Tomar, E Eggens-Meijer, K Bhat, S Copray, AME Walenkamp, E Boddeke, V Balasubramanyian, M Wagemakers, WFA den Dunnen and FAE Kruyt

Cell Death & Disease (Nature) The Netherlands, USA, 02 October 2014

Oncology

Key words: Cell signalling, CNS cancer, Transdifferentiation, Transforming growth factor beta [more]

Adipose tissue–derived stromal cells inhibit TGF-β1–induced differentiation of human dermal fibroblasts and keloid scar–derived fibroblasts in a paracrine fashion

M Spiekman, E Przybyt, JA Plantinga, S Gibbs,B van der Lei, M Harmsen

Plastic and Reconstructive Surgery (Wolters Kluwer) The Netherlands, 01 October 2014

Stem Cell Research

[more]

The Inner Foreskin of Healthy Males at Risk of HIV Infection Harbors Epithelial CD4+ CCR5+ Cells and Has Features of an Inflamed Epidermal Barrier

Maria P Lemos, Javier R Lama, Shelly T Karuna, Youyi Fong, Silvia M Montano, Carmela Ganoza, Raphael Gottardo, Jorge Sanchez, M Juliana McElrath

PLoS One (PLOS) USA, Peru, 30 September 2014

Virology

Key words: Epidermis, inflammation, membrane staining, epithelium, keratinocytes, HIV infections, circumcision HIV [more]

Late effects of local irradiation on the expression of inflammatory markers in the Arteria saphena of C57BL/6 wild-type and ApoE-knockout mice

I Patties, B Habelt, B Rosin, W Dörr, G Hildebrandt, A Glasow

Radiation and Environmental Biophysiscs (Springer) Germany, Austria, 27 September 2014

Immunology

Key words: A. saphe , inflammation, irradiatin , ApoE-knockout mice, atherosclerosis, macrovasculature [more]

CCR9/CCL25 expression in non-small cell lung cancer correlates with aggressive disease and mediates key steps of metastasis

Pranav Gupta, Praveen K Sharma, Hina Mir, Rajesh Singh, Nalinaksha Singh, Goetz H Kloecker, James W Lillard, and Shailesh Singh

Oncotarget (Impact Journals) USA, India, 25 September 2014

Oncology

Key words: CCR9, CCL25, Chemokine receptor, Non-small cell lung cancer [more]

Extracellular matrix components of adipose derived stromal cells promote alignment, organization, and maturation of cardiomyocytes in vitro

Ewa Przybyt, Marja J A van Luyn andMartin C Harmsen

Journal of Biomedical Materials Research (Wiley) The Netherlands, 24 September 2014

Transplantation Medicine

Key words: Myocardial infarction, cardiomyocytes, adipose derived stromal cells, extracellular matrix [more]

Myeloid-derived suppressor cell functionality and interaction with Leishmania major parasites differ in C57BL/6 and BALB/c mice

Maximilian Schmid, Nicole Zimara, Anja Kathrin Wege, Uwe Ritter

European Journal of Immunology (Wiley) Germany, 19 September 2014

Immunology

Key words: Arginase-1, bone marrow, inducible nitric oxide synthase, leishmania major, myeloid-derived suppressor cells [more]

Intratracheal administration of influenza virus is superior to intranasal administration as a model of acute lung injury

Luisa Morales-Nebreda, Monica Chi, Emilia Lecuona, Navdeep S Chandel, Laura A Dada, Karen Ridge, Saul Soberanes, Recep Nigdelioglu, Jacob I Sznajder, Gökhan M Mutlu, GR Scott Budinger, Kathryn A Radigan

Journal of Virological Methods (Elsevier) USA, 17 September 2014

Virology

Key words: Influenza A infection, inoculation, mice, lung injury, intratracheal, intranasal [more]

Antigen-loaded dendritic cell migration: MR imaging in a pancreatic carcinoma model

Zhuoli Zhang , Weiguo Li, Daniele Procissi, Kangan Li, Alexander Y Sheu, Andrew C Gordon, Yang Guo, Khashayarsha Khazaie, Yi Huan, Guohong Han, Andrew C Larson

Radiology (Radiological Society of North America) China, 15 September 2014

Oncology

[more]

Role of TRAP1 and estrogen receptor alpha in patients with ovarian cancer -A study of the OVCAD consortium

Stefanie Aust, Anna Bachmayr-Heyda, Petra Pateisky, Dan Tong, Silvia Darb-Esfahani, Carsten Denkert, Radoslav Chekerov, Jalid Sehouli, Sven Mahner, Toon Van Gorp, Ignace Vergote, Paul Speiser, Reinhard Horvat, Robert Zeillinger, Dietmar Pils

Molecular Cancer (Springer) Austria, Germany, Belgium, The Netherlands, 14 September 2014

Oncology

Key words: TRAP1, estrogen receptorImmunohistochemistry, prognosis, ovarian cancer [more]

Specific roles for dendritic cell subsets during initiation and progression of psoriasis

Elisabeth Glitzner, Ana Korosec, Patrick M Brunner, Barbara Drobits, Nicole Amberg, Helia B Schonthaler, Tamara Kopp, Erwin F Wagner, Georg Stingl, Martin Holcmann,Maria Sibilia

EMBO Molecular Medicine (EMBO press) Austria, Spain, 12 September 2014

Dermatology

Key words: AP-1, IL-23, langerhans cells, plasmacytoid dendritic cells, psoriasis [more]

An Activatable Prodrug for the Treatment of Metastatic Tumors

Eun-Joong Kim, Sankarprasad Bhuniya, Hyunseung Lee, Hyun Min Kim, Chaejoon Cheong, Sukhendu Maiti, Kwan Soo Hong, Jong Seung Kim

Journal of the American Chemical Society (ACS Publications) South Korea, 11 September 2014

Oncology

Key words: Metastatic cancers, tumor cell growth, cellular imaging [more]

Olfactory Receptor Patterning in a Higher Primate

Lisa F Horowitz, Luis R Saraiva, Donghui Kuang, Kyoung-hye Yoon, Linda B Buck

Journal of Neuroscience (SFN) USA, 10 September 2014

Neuroscience

Key words: Macaque odorant receptor, primate trace-amine associated receptor [more]

Late inflammatory and thrombotic changes in irradiated hearts of C57BL/6 wild-type and atherosclerosis-prone ApoE-deficient mice

I Patties, J Haagen, W Dörr, G Hildebrandt, A Glasow

Strahlentherapie und Onkologie (Springer) Germany, Austria, 09 September 2014

Radiotherapy

Key words: Irradiatio, n microvasculature, Heart Inflammation, Atheroscrosis Bestrahlung, Mikrovaskulatur, Herz Entzündung Atherosklerose [more]

Energy metabolism analysis reveals the mechanism of inhibition of breast cancer cell metastasis by PEG-modified graphene oxide nanosheets

Teng Zhoua, Bo Zhang, Peng Wei,Yipeng Du, Hejiang Zhou, Meifang Yu, Liang Yan, Wendi Zhang, Guangjun Nie, Chunying Chen, Yaping Tu, Taotao Wei

Biomaterials (Elsevier) China, USA, 08 September 2014

Nanomedicine

Key words: PEG-modified graphene oxide, breast cancer cell, metastasis, cytoskeletal assembly, mitochondrial oxidative phosphorylation [more]

STAT3β controls inflammatory responses and early tumor onset in skin and colon experimental cancer models

Francesca Marino, Valeria Orecchia, Gabriella Regis, Monica Musteanu, Beatrice Tassone, Cristina Jon, Marco Forni, Enzo Calautti, Roberto Chiarle, Robert Eferl, and Valeria Poli

American Journal of Cancer Research (NCBI) Italy, Austria, Spain, USA, 06 September 2014

Oncology

Key words: STAT3 isoforms, STAT3β, inflammation, inflammation-driven tumorigenesis, colitis-associated cancer, AOM/DSS protocol, skin tumorigenesis, DMBA/TPA protocol, genetically modified mice [more]

Optimisation of the quantitative analysis of inflammatory cell infiltrates in breast cancer/Optimizarea analizei cantitative a infiltratului celular inflamator în cancerul …

AR Vrânceanu, CC Tărniceriu, D Jitaru, C Terinte, F Zugun-Eloae, E Carasevici

Revista Romana de Medicina de Laborator () Romania, 03 September 2014

Oncology

[more]

NEW INSIGHTS IN PULMONARY HYPERTENSION

European Heart Journal (Oxford University Press) Italy, 31 August 2014

Cardiology

Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix

Leila Akkari, Vasilena Gocheva, Jemila C Kester, Karen E Hunter, Marsha L Quick, Lisa Sevenich, Hao-Wei Wang, Christoph Peters, Laura H Tang, David S Klimstra, Thomas Reinheckel, Johanna A Joyce

Genes and Development (CSH Press) USA, Germany, 29 August 2014

Oncology

Key words: Cell invasion, cell migration, tumor microenvironment protease [more]

Quantitative LA-ICP-MS imaging of platinum in chemotherapy treated human malignant pleural mesothelioma samples using printed patterns as standard

M Bonta, H Lohninger, V Laszlo, B Hegedus, A Limbeck

Journal of Analytical Atomic Spectrometry (Royal Society of Chemistry) Austria, Hungary, 29 August 2014

Oncology

[more]

Macrophage Migration Inhibitory Factor Triggers Chemotaxis of CD74+CXCR2+ NKT Cells in Chemically Induced IFN-γ–Mediated Skin Inflammation

Chia-Yuan Hsi, Chia-Ling Chen, Yee-Shin Lin, Trai-Ming Yeh, Tsung-Ting Tsai, Ming-Yuan Hong, Chiou-Feng Lin

The Journal of Immunology (American Association of Immunologists) Taiwan, 29 August 2014

Immunology

Key words: Human NK cell, macrophage migration inhibitory factor [more]

Vascularization of primary and secondary ossification centres in the human growth plate

Sonja M Walzer, Erdal Cetin, Ruth Grübl-Barabas, Irene Sulzbacher, Beate Rueger, Werner Girsch, Stefan Toegel, Reinhard Windhager, Michael B Fischer

BMC Developmental Biology (Springer) Austria, 28 August 2014

Developmental Biology

Key words: Growth plate, vascularization, primary ossification centres, secondary ossification centres, progenitor cells [more]

Type I interferons have opposing effects during the emergence and recovery phases of colitis

Isabella Rauch, Eva Hainzl, Felix Rosebrock, Susanne Heider, Clarissa Schwab, David Berry, Dagmar Stoiber, Michael Wagner, Christa Schleper, Alexander Loy, Tim Urich, Mathias Müller, Birgit Strobl, Lukas Kenner,Thomas Decker

European Journal of Immunology (Wiley) Austria, 25 August 2014

Immunology

Key words: Colitis, inflammation, interferons, interleukin-1, microbiota [more]

Shock Wave Treatment Enhances Cell Proliferation and Improves Wound Healing by ATP Release-coupled Extracellular Signal-regulated Kinase (ERK) Activation

Anna M Weihs, Christiane Fuchs, Andreas H Teusch, Joachim Hartinger, Paul Slezak, Rainer Mittermayr, Heinz Redl§,Wolfgang G Junger, Harald H Sitte, Dominik Rünzler

Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) Austria, 12 August 2014

Regenerative Medicine

Key words: ATP Cell proliferation, extracellular signal-regulated kinase (ERK), signal transduction, wound healing, shock wave treatment [more]

Histological Characterization and Quantification of Cellular Events Following Neural and Fibroblast(-Like) Stem Cell Grafting in Healthy and Demyelinated CNS Tissue

Jelle Praet, Eva Santermans, Kristien Reekmans, Nathalie de Vocht, Debbie Le Blon, Chloé Hoornaert, Jasmijn Daans, Herman Goossens, Zwi Berneman, Niel Hens, Annemie Van der Linden, Peter Ponsaert

Animal Models for Stem Cell Therapy (Springer) Belgium, 04 August 2014

Stem Cell Research

Key words: Neural stem cell, mouse embryonic fibroblasts, cell grafting, cuprizone, quantitative histology, inflammation

Analysis of tumour-and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S

Lisa Sevenich, Robert L Bowman, Steven D Mason, Daniela F Quail, Franck Rapaport, Benelita T Elie, Edi Brogi, Priscilla K Brastianos, William C Hahn, Leslie J Holsinger, Joan Massagué, Christina S Leslie and Johanna A Joyce

Nature Cell Biology (Nature) USA, 03 August 2014

Oncology

Key words: Cancer microenvironment, Metastasis [more]

Benzyl butyl phthalate induces migration, invasion, and angiogenesis of Huh7 hepatocellular carcinoma cells through nongenomic AhR/G-protein signaling

Cheng-Fang Tsai, Tsung-Hua Hsieh, Jau-Nan Lee, Chia-Yi Hsu, Yu-Chih Wang, Feng-Jie Lai, Kung-Kai Kuo, Hua-Lin Wu, Eing-Mei Tsai and Po-Lin Kuo

BMC Cancer (Springer) Taiwan, 01 August 2014

Oncology

Key words: Phthalate, Aryl hydrocarbon receptor, Angiogenesis, Migration, Hepatocellular carcinoma [more]

The vitamin D system is deregulated in pancreatic diseases

Doris Hummel, Abhishek Aggarwal, Katalin Borka, Erika Bajna, Enikö Kállay, Henrik Csaba Horváth

The Journal of Steroid Biochemistry and Molecular Biology (Elsevier) Austria, Hungary, Switzerland, 30 July 2014

Oncology

Key words: Vitamin D, CYP24A1, VDR, CaSR, chronic pancreatitis, pancreatic ductal adenocarcinoma, pancreatic cancer [more]

Hardware and Software

Yves Sucaet, Wim Waelput

Hardware and Software (Springer) Belgium, 23 July 2014

Medical Imaging

Key words: Digital pathology, slide scanner, tile scanner, line scanner, file format, medical imaging WSI DP MRXS NDPI SVS BIF

Single Administration of p2TA (AB103), a CD28 Antagonist Peptide, Prevents Inflammatory and Thrombotic Reactions and Protects against Gastrointestinal Injury in Total-Body Irradiated Mice

Salida Mirzoeva, Tatjana Paunesku, M Beau Wanzer, Anat Shirvan, Raymond Kaempfer, Gayle E Woloschak, William Small Jr

PLoS One (PLOS) USA, Israel, 23 July 2014

Gastroenterology

Key words: Inflammation, ayclins, fibrinogen, macrophages, gamma rays, cytokines, infrared radiation, small intestine [more]

Absence of substance P and the sympathetic nervous system impact on bone structure and chondrocyte differentiation in an adult model of endochondral ossification

Tanja Niedermaira, Volker Kuhn, Fatemeh Doranehgard, Richard Stange, Britta Wieskötter, Johannes Beckmann, Philipp Salmen, Hans-Robert Springorum, Rainer H Straub, Andreas Zimmer, Joachim Grifka, Susanne Grässel

Matrix Biology (Elsevier) Germany, Austria, 22 July 2014

Neuroscience

Key words: Substance P, sympathetic nerve fibers, fracture callus, bone structure, bone formation, bone resorption, biomechanics, endochondral ossification [more]

Wnt Coreceptor Lrp5 Is a Driver of Idiopathic Pulmonary Fibrosis

Anna P Lam , Jose D Herazo-Maya , Joseph A Sennello , Annette S Flozak , Susan Russell , Gökhan M Mutlu , G R Scott Budinger , Ramanuj DasGupta , John Varga , Naftali Kaminski , and Cara J Gottardi

American Journal of Respiratory and Critical Care Medicine (ATS Journals) USA, 15 July 2014

Pulmonology

Key words: lung fibrosis, Wnt/β-catenin signaling, peripheral blood mononuclear cell [more]

Reliable Quantification of Protein Expression and Cellular Localization in Histological Sections

Michaela Schlederer, Kristina M Mueller, Johannes Haybaeck, Susanne Heider, Nicole Huttary, Margit Rosner, Markus Hengstschläger, Richard Moriggl, Helmut Dolznig, Lukas Kenner

PLoS One (PLOS) Austria, 11 July 2014

Pathology

Key words: Image analysis, pathologists, cell staining, hepatocytes, protein expression, cytoplasmic staining, transcription factors, hepatocellular carcinoma [more]

EpCAM is overexpressed in local and metastatic prostate cancer, suppressed by chemotherapy and modulated by MET-associated miRNA-200c/205

P Massoner, T Thomm, B Mack, G Untergasser, A Martowicz, K Bobowski, H Klocker, O Gires and M Puhr

British Journal of Cancer (Nature) Austria, Germany, 03 July 2014

Oncology

Key words: Biomarkers, Cancer therapeutic resistance, Oncogenesis, Prostate cancer [more]

Alteration in the Wnt microenvironment directly regulates molecular events leading to pulmonary senescence

Tamas Kovacs, Veronika Csongei, Diana Feller, David Ernszt, Gabor Smuk, Veronika Sarosi, Laszlo Jakab, Krisztian Kvell, Domokos Bartis Judit E Pongracz

Aging Cell (Wiley) Hungary, UK, 01 July 2014

Cell Biology

Key words: Molecular biology of aging, pulmonary senescence, Wnt microenvironment [more]

Distinct spatial distribution of microglia and macrophages following mesenchymal stem cell implantation in mouse brain

Debbie Le Blon, Chloé Hoornaert, Jasmijn Daans, Eva Santermans, Niel Hens, Herman Goossens, Zwi Berneman, Peter Ponsaerts

Immunology and Cell Biology (Wiley) Belgium, 01 July 2014

Immunology

[more]

Comprehensive assessment of HIV target cells in the distal human gut suggests increasing HIV susceptibility toward the anus

MJ McElrath, K Smythe, J Randolph-Habecker, KR Melton, TA Goodpaster, S Hughes, M Mack, A Sato, G Diaz, G Steinbach, R Novak, M Curlin, JD Lord, J Maenza, A Duerr, N Frahm, F Hladik

Journal of acquired immune deficiency Syndrome (NCBI) USA, Germany, 01 July 2014

Virology

[more]

Podocalyxin-like 1 promotes invadopodia formation and metastasis through activation of Rac1/Cdc42/cortactin signaling in breast cancer cells

Cheng-Wei Lin, Min-Shiou Sun, Mei-Ying Liao, Chu-Hung Chung, Yi-Hsuan Chi, Li-Tin Chiou, John Yu, Kuo-Lung Lou, Han-Chung Wu

Carcinogenesis (Oxford University Press) Taiwan, 26 June 2014

Oncology

Key words: Podocalyxin-like 1 invadopodia, cortactin invasion metastasis [more]

Memantine Alleviates Brain Injury and Neurobehavioral Deficits after Experimental Subarachnoid Hemorrhage

Chih-Yuan Huang, Liang-Chao Wang, Hao-Kuang Wang, Chia-Hsin Pan, Ya-Yun Cheng, Yan-Shen Shan, Chung-Ching Chio, Kuen-Jer Tsai

Molecular Neurobiology (Springer) Taiwan, 22 June 2014

Neuroscience

Key words: Blood-brain barrier, memantine, neuroprotection, nitric oxide synthase, subarachnoid hemorrhage [more]

OP0103 Decreased Lupus Severity in Mir155 Deficient Mice

H Leiss, W Salzberger, I Gessl, N Kozakowski, S Blüml, A Puchner, B Niederreiter, G Steiner, J Smolen, G Stummvoll

Annals of the Rheumatic Diseases (BMJ Journals) Austria, 14 June 2014

Rheumatology

Key words: MicroRNAs, MiR155-deficient, glomerulonephritis, serum antibody, T helper cell homeostasis [more]

OP0300 Effect of VEGF121-Fibrin on the Expression of VEGF Receptors in Ischemic Lesions of UCD-206 Chickens, an Animal Model for Systemic Sclerosis

S Allipour-Birgani, H Dietrich, J Gruber, O Distler, A Zisch, R Sgonc

Annals of the Rheumatic Diseases (BMJ Journals) Austria, Switzerland, 14 June 2014

Rheumatology

Key words: Systemic sclerosis, perivascular mononuclear cell infiltration, Microvascular injury, angiogenesis, vascular endothelial cell growth factor [more]

An integrated approach for the systematic evaluation of polymeric nanoparticles in healthy and diseased organisms

Leopoldo Sitia, Katia Paolella, Michela Romano, Martina Bruna Violatto, Raffaele Ferrari, Stefano Fumagalli, Laura Colombo, Ezia Bello, Maria Grazia De Simoni, Maurizio D’Incalci, Massimo Morbidelli, Eugenio Erba, Mario Salmona, Davide Moscatelli, Paolo Bigini

Journal of Nanoparticle Research (Springer) Italy, Switzerland, 12 June 2014

Nanomedicine

Key words: Optical imaging, cellular uptake, protein corona, breast tumor, cell cycle phase, nu nu mouse, atomic force microscopy, lymph node, involvment, intracellular delivery, tumor vasculature [more]

A hormone-dependent feedback-loop controls androgen receptor levels by limiting MID1, a novel translation enhancer and promoter of oncogenic signaling

Andrea Köhler, Ümmühan Demir, Eva Kickstein, Sybille Krauss, Johanna Aigner, Beatriz Aranda-Orgillés, Antonios I Karagiannidis, Clemens Achmüller, Huajie Bu, Andrea Wunderlich, Michal-Ruth Schweiger, Georg Schaefer, Susann Schweiger, Helmut Klocker, Rainer Schneider

Molecular Cancer (Springer) Austria, Germany, UK, 09 June 2014

Oncology

Key words: Androgen receptor, MID1, Translation, Prostate cancer, Reciprocal regulation [more]

B Cells and Ectopic Follicular Structures: Novel Players in Anti-Tumor Programming with Prognostic Power for Patients with Metastatic Colorectal Cancer

Anastasia Meshcheryakova, Dietmar Tamandl, Erika Bajna, Judith Stift, Martina Mittlboeck, Martin Svoboda, Denise Heiden, Stefan Stremitzer, Erika Jensen-Jarolim, Thomas Grünberger, Michael Bergmann, Diana Mechtcheriakova

PLoS One (PLOS) Austria, 06 June 2014

Immunology

Key words: B cells, immune cells, macrophages, cell staining, portal veins, colorectal cancer, DAPI staining, nuclear staining [more]

Angiogenesis as prospective molecular biology technique for cancer study

Grigore T Popa

Romanian Biotechnological Letters (University of Bucharest) Romania, 03 June 2014

Oncology

Key words: esophagus, tumor, neoangiogenesis, quantitative study [more]

Circulating Cytokines and Alarmins Associated with Placental Inflammation in High-Risk Pregnancies

Sylvie Girard, Alexander E P Heazell, Hayley Derricott, Stuart M Allan, Colin P Sibley, Vikki M Abrahams, Rebecca L Jones

American Journal of Reproductive Immunology (Wiley) UK, USA, Canada, 28 May 2014

Reproductive Medicine

Key words: High-risk pregnancy, inflammation, placental dysfunction, stillbirth [more]

A novel rat full-thickness hemi-abdominal wall/hindlimb osteomyocutaneous combined flap: influence of allograft mass and vascularized bone marrow content on vascularized composite allograft survival

Alejandro E Ramirez, Hui-Yun Cheng3, William W Lao, Yen-Ling Wang, Chih-Jen Wen, Christopher G Wallace, Chih-Fan Lin, Ling-Yi Shih, Sheng-Hao Chuang and Fu-Chan Wei

Transplant International (Wiley) Taiwan, Chile, USA, 24 May 2014

Transplantation Medicine

Key words: Abdominal wall transplantation, allograft mass, allograft survival, combined flap, vascularized bone marrow, vascularized composite allotransplantation [more]

Coexpression of CD44-positive/CD133-positive cancer stem cells and CD204-positive tumor-associated macrophages is a predictor of survival in pancreatic ductal adenocarcinoma

Ya-Chin Hou, Ying-Jui Chao, Hui-Ling Tung, Hao-Chen Wang, Yan-Shen Shan

Cancer (Wiley) Taiwan, 19 May 2014

Oncology

Key words: Pancreatic ductal adenocarcinoma, cancer stem cells, tumor-associated macrophages, tissue microarrays, CD44, CD133, CD204 [more]

Cav3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage

Shin-Shiou Lin, Bing-Hsiean Tzeng,Kuan-Rong Lee, Richard J H Smith, Kevin P Campbell, Chien-Chang Chen

PNAS (PNAS) Taiwan, USA, 13 May 2014

Physiology

Key words: Chondrogenesis, tracheal cartilage, mesenchymal cells, chondrocytes [more]

Cell cycle association and hypoxia regulation of excision repair cross complementation group 1 protein (ERCC1) in tumor cells of head and neck cancer

József Dudás, Volker H Schartinger, Angela Romani, Gabriele Schweigl, Kristian Kordsmeyer, Patricia Irina Marta, Christoph Url, Florian Kral, Herbert Riechelmann

Tumor Biology (Springer) Austria, 12 May 2014

Oncology

Key words: Gene expression, cell cycle phase, bronchial epithelial cell, nuclear extract [more]

Relevance of estrogen activating STS and inactivating SULT1E1 enzymes and estrogen receptors [alpha/beta] in patients with advanced ovarian cancer

Felicitas Mungenast, Stefanie Aust, Martin Svoboda, Katharina Ocko, Lukas Klameth, Dan Cacsire Castilo-Tong, Robert Zeillinger, Toon Van Gorp, Ignace Vergote, Ioana Braicu, Jalid Sehouli, Sven Mahner, M Fogel and Theresia Thalhammer

16th European Congress of Endocrinology (Endocrine Abstracts) Austria, Belgium, Germany, Israel, 07 May 2014

Oncology

A new rat model for orthotopic abdominal wall allotransplantation

WW Lao, YL Wang, AE Ramirez, HY Cheng, FC Wie

Plastic Reconstruction Surgery Global open (NCBI) Taiwan, 07 May 2014

Oncology

[more]

1172 (pp34) myocardial Biopsy for the Validation of Cardiac Magnetic Resonance T1 Mapping for Quantification of Extracellular Matrix

A Kammerlander, C Tufaro, S Pfaffenberger, B Marzluf, S Aschauer, J Babayev, D Bonderman, J Mascherbauer

European Heart Journal (Oxford University Press) Austria, 01 May 2014

Cardiology

[more]

A new fluorescence/PET probe for intracellular human telomerase reverse transcriptase (hTERT) using Tat peptide-conjugated antibody

Kyung Oh Jung, Hyewon Youn, Mi Jeong Kim, Keon Wook Kang, Dong Soo Lee and June-Key Chung

The Journal of Nuclear Medicine () South Korea, 01 May 2014

Biological Methods

[more]

Increase of Zinc Finger Protein 179 in Response to CCAAT/Enhancer Binding Protein Delta Conferring an Antiapoptotic Effect in Astrocytes of Alzheimer’s Disease

Shao-Ming Wang, Yi-Chao Lee, Chiung-Yuan Ko, Ming-Derg Lai, Ding-Yen Lin, Ping-Chieh Pao, Jhih-Ying Chi, Yu-Wei Hsiao, Tsung-Lin Liu, Ju-Ming Wang

Molecular Neurobiology (Springer) Taiwan, 01 May 2014

Neuroscience

Key words: Alzheimer's disease CEBPD ZNF179, astrocytes, antiapoptosis [more]

PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors

Rieko Ohki, Kozue Saito, Yu Chen, Tatsuya Kawase, Nobuyoshi Hiraoka, Raira Saigawa, Maiko Minegishi, Yukie Aita, Goichi Yanai, Hiroko Shimizu, Shinichi Yachida, Naoaki Sakata, Ryuichiro Doi, Tomoo Kosugi, Kazuaki Shimada, Benjamin Tycko, Toshihiko Tsukada, Yae Kanai, Shoichiro Sumi, Hideo Namiki, Yoichi Taya, Tatsuhiro Shibata, Hitoshi Nakagama

PNAS (PNAS) Japan, 01 May 2014

Oncology

Key words: p53 PH domain everolimus p53 target gene mTOR [more]

ISAC XXII International Congress

ISAC XXII International Congress

Cytometry Part A (Wiley) , 21 April 2014

Cytometry

Epicutaneously applied Der p 2 induces a strong TH2-biased antibody response in C57BL/6 mice, independent of functional TLR4

C Stremnitzer, K Manzano-Szalai, P Starkl, A Willensdorfer, S Schrom, J Singer, U Reichart, S Akira, E Jensen-Jarolim

Allergy (Wiley) Austria, 16 April 2014

Allergy Research

Key words: Allergic dermatitis, Der p 2, house dust mite, LPS, TLR4 [more]

Direct comparison of the dynamics of IL-25- and ‘allergen’-induced airways inflammation, remodelling and hypersensitivity in a murine asthma model

X J Yao, K W Huang, Y Li, Q Zhang, J J Wang, W Wang, J Liu, Z Lv, Y Q An, Y Z Ding, C J Corrigan, W Wang, Y C Sun, S Ying

Clinical and Experimental Allergy (Wiley) China, UK, 16 April 2014

Allergy Research

Key words: Asthma, IL-25, IL-25 receptor, murine model, pathogenesis, remodelling [more]

Poly(lactide-co-glycolide) microspheres for MRI-monitored transcatheter delivery of sorafenib to liver tumors

Jeane Chen, Alexander Y Sheu, Weiguo Li, Zhuoli Zhang, c, Dong-Hyun Kim, Robert J Lewandowski, Reed A Omary, Lonnie D Shea, Andrew C Larson

Journal of Controlled Release (Elsevier) USA, 13 April 2014

Oncology

Key words: Sorafenib, hepatocellular carcinoma, magnetic resonance imaging, poly(lactide-co-glycolide) [more]

Abstract 1662: Towards automated analysis of prostate inflammatory state: Assessing density and distance of infiltrating T-cells (CD3+) to glandular structures in prostate biopsies by a new software

Radu Rogojanu, Bogdan Boghiu, Georg Schaefer, Theresia Thalhammer, Georg Steiner, Rupert Ecker, Bettina Schlick, Thomas Szekeres, Isabella Ellinger

Cancer Research (AACR Publications) Austria, Romania, 09 April 2014

Medical Image Analysis

Key words: Biopsies, automated analysis [more]

T cell-associated α4β7 but not α4β1 integrin is required for the induction and perpetuation of chronic colitis

E Kurmaeva, JD Lord, S Zhang, JR Bao, CG Kevil, MB Grisham and DV Ostanin

Mucosal Immunology (Nature) USA, 09 April 2014

Immunology

Key words: Antibody therapy, Colitis, Crohn's disease, Mucosal immunology [more]

Calcium-sensing receptor silencing in colorectal cancer is associated with promoter hypermethylation and loss of acetylation on histone 3

Irfete S Fetahu, Julia Höbaus, Abhishek Aggarwal, Doris M Hummel, Samawansha Tennakoon, Ildiko Mesteri, Sabina Baumgartner-Parzer, Eniko Kállay

International Journal of Cancer (Wiley) Austria, 02 April 2014

Oncology

Key words: Calcium-sensing receptor, DNA methylation, histone acetylation, histone methylation, colorectal cancer [more]

Oncogenic functions of IGF1R and INSR in prostate cancer include enhanced tumor growth, cell migration and angiogenesis

I Heidegger, J Kern, P Ofer, H Klocker, P Massoner

Oncotarget (Impact Journals) Austria, 02 April 2014

Oncology

Key words: Prostate cancer, IGF targeting therapies, insulin-like growth factor receptor-1 (IGF1R), insulin receptor (INSR) [more]

Transplantation of cyclic stretched fibroblasts accelerates the wound-healing process in streptozotocin-induced diabetic mice

E Lee, DY Kim, E Chung, EA Lee, KS Park, Y Son

Cell Transplantation (SAGE Journals) South Korea, 01 April 2014

Transplantation Medicine

Key words: Cell survival, Cyclic stretch, Mechanical stimulus, Angiogenesis, Wound healing [more]

Protective effect of magnesium and metformin on endometrium and ovary in experimental diabetes mellitus

C Gales, C Zamfir, D Radulescu, B Stoica, M Nechifor

Magnesium research (John Libbey) Romania, 01 April 2014

Reproductive Medicine

Key words: magnesium, endometrium, ovary, diabetes mellitus [more]

Muscle–fat MRI: 1.5 tesla and 3.0 tesla versus histology

Andrew C Smith, Todd B Parrish, Rebecca Abbott, Mark A Hoggarth, Karl Mendoza, Yu Fen Chen, James M Elliott

Muscle and nerve (Wiley) USA, 28 March 2014

Medical Imaging

Key words: MRI, muscle fat infiltrates, muscle imaging, muscle/fat fraction, muscle, fat [more]

Oxygen therapy does not increase production and damage induced by reactive oxygen species in focal cerebral ischemia

Li Suna, Guido Wolfertsb, Roland Veltkamp

Neuroscience Letters (Elsevier) Germany, 28 March 2014

Neuroscience

Key words: Cerebral ischemia, oxygen therapy, HBO, reactive oxygen species, SOD2 [more]

Myofibroblasts in Murine Cutaneous Fibrosis Originate From Adiponectin-Positive Intradermal Progenitors

Roberta Goncalves Marangoni, Benjamin D Korman, Jun Wei, Tammara A Wood, Lauren V Grham, Michael L Whithfield, Philipp E Scherrr, Warren G Tourtellott, John Varga

Arthritis & Rheumatology (Wiley) USA, 27 March 2014

Rheumatology

Key words: Myofibroblasts, systemic sclerosis, growth factor β, canonical adipogenic markers [more]

In vivo real-time fluorescence visualization and brain-targeting mechanisms of lipid nanocarriers with different fatty ester:oil ratios

Chih-Jen Wen, Tzu-Chen Yen, Saleh A Al-Suwayeh, Hui-Wen Chang, Jia-You Fang

Future Medicine (FSG) Taiwan, Saudi Arabia, 27 March 2014

Nanomedicine

Key words: Lipid nanocarriers, cetyl palmitate, squalene, sulforhodamine B [more]

RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis

Marion Lapierre, Sandrine Bonnet, Caroline Bascoul-Mollevi, Imade Ait-Arsa, Stéphan Jalaguier, Maguy Del Rio, Michela Plateroti, Paul Roepman, Marc Ychou, Julie Pannequin, Frédéric Hollande, Malcolm Parker, and Vincent Cavailles1

The Journal of Clinical Investigation (American Society for Clinical Investigation) France, The Netherlands, UK, 25 March 2014

Oncology

[more]

Ambivalent role of pFAK-Y397 in serous ovarian cancer-a study of the OVCAD consortium

Stefanie Aust, Katharina Auer, Anna Bachmayr-Heyda, Carsten Denkert, Jalid Sehouli, Ioana Braicu, Sven Mahner, Sandrina Lambrechts, Ignace Vergote, Christoph Grimm, Reinhard Horvat, Dan Cacsire Castillo-Tong, Robert Zeillinger Dietmar Pils

Molecular Cancer (Springer) Austria, Germany, Belgium, 21 March 2014

Oncology

Key words: FAK, pFAK, molecular subclassification, immunohistochemistry, prognosis, ovarian cancer [more]

Protection against Dengue Virus Infection in Mice by Administration of Antibodies against Modified Nonstructural Protein 1

Shu-Wen Wan, Yi-Tien Lu, Chia-Hui Huang, Chiou-Feng Lin, Robert Anderson, Hsiao-Sheng Liu, Trai-Ming Yeh, Yu-Ting Yen, Betty A Wu-Hsieh , Yee-Shin Lin

PLoS One (PLOS) Taiwan, Canada, 21 March 2014

Virology

Key words: Hemorrhage, endothelial cells, platelets, complement system, dengue fever, hematoxylin staining, inoculation, macrophages [more]

Lamin B2 prevents chromosome instability by ensuring proper mitotic chromosome segregation

T Kuga, H Nie, T Kazami, M Satoh, K Matsushita, F Nomura, K Maeshima, Y Nakayama and T Tomonaga

Oncogenesis (Nature) Japan, 17 March 2014

Oncology

Key words: Chromosome segregation, Colorectal cancer, Mitotic spindle [more]

Hedgehog Pathway Inhibition in Chondrosarcoma Using the Smoothened Inhibitor IPI-926 Directly Inhibits Sarcoma Cell Growth

Veronica T Campbell, Puviindran Nadesan, S Amanda Ali, Chang Ye Yale Wang, Heather Whetstone, Raymond Poon, Qingxia Wei, John Keilty, Jennifer Proctor, Lauren W Wang, Suneel S Apte, Karen McGovern, Benjamin A Alman, Jay S Wunder

Molecular Cancer Therapeutics (AACR Publications) USA, Canada, 14 March 2014

Oncology

Key words: Hedgehog (Hh) pathway, Chondrosarcoma, transmembrane receptor Patched [more]

Blockade of Fas Signaling in Breast Cancer Cells Suppresses Tumor Growth and Metastasis via Disruption of Fas Signaling-initiated Cancer-related Inflammation

Qiuyan Liu, Qinchun Tan, Yuanyuan Zheng, Kun Chen, Cheng Qia, Nan Li, Qingqing Wang, Xuetao Cao

Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) China, 13 March 2014

Oncology

Key words: Breast Cancer, fas inflammation, prostaglandins, tumor metastases IL-6 MDSC PGE2 [more]

Interleukin-1β Attenuates Myofibroblast Formation and Extracellular Matrix Production in Dermal and Lung Fibroblasts Exposed to Transforming Growth Factor-β1

Masum M Mia, Ruud A Bank, Miriam Boersema

PLoS One (PLOS) The Netherlands, 12 March 2014

Cell Biology

Key words: Fibroblasts, collagens, gene expression, fibrosis, immunofluorescence staining, tissue repair, cytokines, lungs [more]

5th International meeting on angiogenesis

Angiogenesis (Springer) The Netherlands, 08 March 2014

Regenerative Medicine

Impact of the Smoothened Inhibitor, IPI-926, on Smoothened Ciliary Localization and Hedgehog Pathway Activity

Marisa O Peluso, Veronica T Campbell, Joseph A Harari, Thomas T Tibbitts, Jennifer L Proctor, Nigel Whitebread, James M Conley, Kerry F White, Jeffery L Kutok, Margaret A Read, Karen McGovern, Kerrie L Faia

PLoS One (PLOS) USA, 07 March 2014

Oncology

Key words: Hedgehog signaling NIH 3T3 cells, cancer treatment, cell binding assay, cilia, gene expression, luciferase, cell staining [more]

Excessive activation of the alternative complement pathway in autosomal dominant polycystic kidney disease

Z Su, X Wang, Gao,YLiu, CPan, H Hu, R P Beyer, M Shi, J Zhou, J Zhang, A L Serra, R P Wüthrich, C Mei

Journal of Internal Medicine (Wiley) China, Switzerland, USA, 02 March 2014

Nephrology

Key words: Autosomal dominant polycystic kidney disease, complement, complement inhibitor, glycoproteomics, urine [more]

AB0206 Altered Expression of Angiopoietins and Tie-2 in Ischemic Lesions of UCD-206 Chickens, an Animal Model for Systemic Sclerosis

S Allipour Birgani, H Dietrich, R Sgonc

Annals of the Rheumatic Diseases (BMJ Journals) Austria, 01 March 2014

Rheumatology

Key words: Systemic sclerosis, vascular endothelial growth factor , endothelial cells

Multimodality imaging to assess immediate response to irreversible electroporation in a rat liver tumor model

Yue Zhang, Sarah B White, Jodi R Nicolai, Zhuoli Zhang, Derek L West, Dong-hyun Kim, A Lee Goodwin, Frank H Miller, Reed A Omary, Andrew C Larson

Radiology (Radiological Society of North America) USA, 18 February 2014

Oncology

[more]

Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma

Winnie W Lo, Jay S Wunder, Brendan C Dickson, Veronica Campbell, Karen McGovern , Benjamin A Alman, Irene L Andrulis

Cancer (Wiley) Canada, USA, 15 February 2014

Oncology

Key words: Osteosarcoma, hedgehog signaling, ligand-dependent, IPI-926, microenvironment [more]

Iron deficiency alters megakaryopoiesis and platelet phenotype independent of thrombopoietin

Rayko Evstatiev, Adam Bukaty, Kristine Jimenez, Stefanie Kulnigg-Dabsch, Lidia Surman, Werner Schmid, Robert Eferl, Kathrin Lippert, Barbara Scheiber-Mojdehkar, Hans Michael Kvasnicka, Vineeta Khare, Christoph Gasch

American Journal of Hematology (Wiley) Austria, Germany, 14 February 2014

Hematology

Key words: Iron deficiency [more]

NKG2D+ IFN-γ+ CD8+ T Cells Are Responsible for Palladium Allergy

Mitsuko Kawano, Masafumi Nakayama, Yusuke Aoshima, Kyohei Nakamura, Mizuho Ono, Tadashi Nishiya, Syou Nakamura, Yuri Takeda, Akira Dobashi, Akiko Takahashi, Misato Endo, Akiyo Ito, Kyosuke Ueda, Naoki Sato, Shigehito Higuchi, Takeru Kondo, Suguru Hashimoto, Masamichi Watanabe, Makoto Watanabe, Tetsu Takahashi,Keiichi Sasaki, Masanori Nakamura, Takehiko Sasazuki, Takayuki Narushima, Ryuji Suzuki, Kouetsu Ogasawara

PLoS One (PLOS) Japan, 12 February 2014

Allergy Research

Key words: T cells, cytotoxic T cells, allergies, mouse models, adoptive transfer, lymphocytes, allergy immunotherapy, lymph nodes [more]

Successful treatment of adult onset Langerhans cell histiocytosis with bi-weekly administration of pegylated interferon-α

Sadanori Furudate, Taku Fujimura, Yumi Kambayashi, Mitsuko Kawano, Kouetsu Ogasawara, Akira Tsukada, Erika Tamabuchi, Takahiro Haga, Akira Hashimoto and Setsuya Aiba

Acta Dermato Venereologica (Ingentaconnect) Japan, 04 February 2014

Dermatology

[more]

Serum Level of IL-10 Is Increased in Patients with Endometriosis, and IL-10 Promotes the Growth of Lesions in a Murine Model

Jau-Ling Suen, Yu Chang, Pu-Rong Chiu, Tsung-Hua Hsieh, Edward Hsi, Yu-Chieh Chen, Yu-Fang Chen, Eing-Mei Tsai

The American Journal of Pathology (American Society for Investigative Pathology) Taiwan, 01 February 2014

Pathology

Key words: Immune dysregulation, anti-inflammatory cytokine IL-10, Monocyte-derived dendritic cells [more]

Metformin anti-tumor effect via disruption of the MID1 translational regulator complex and AR downregulation in prostate cancer cells

Ummuhan Demir, Andrea Koehler, Rainer Schneider, Susann Schweiger, Helmut Klocker

BMC Cancer (Springer) Austria, Germany, 31 January 2014

Oncology

Key words: Metformin, Androgen receptor, MID1-α4/PP2A protein complex, AMPK , Translational regulation, CoIP [more]

Role of oncogenic K-Ras in cancer stem cell activation by aberrant Wnt/β-catenin signaling

BS Moon, WJ Jeong, J Park, TI Kim, DS Min, KY Choi

Journal of the National Cancer Institute (Oxford University Press) South Korea, 31 January 2014

Oncology

Key words: signal transduction, mutation, cd44 antigens, transplantation, heterologous, mice, neoplasms, k-ras oncogene, homing-associated cell adhesion molecule, cancer stem cells [more]

Die prognostische Bedeutung von Tumor-infiltrierenden CD8+Zellen: eine detaillierte Analyse in Hinblick auf Tumor-Debulking und Zell-Proliferation

S Aust, A Bachmayr-Heyda, S Polterauer, D Pils, DC Castillo-Tong, OVCAD Consortium

Geburtshilfe und Frauenheilkunde (Thieme) Austria, 30 January 2014

Immunology

The role of the organic anion transporting polypeptide OATP4A1 in immunactivation in colorectal cancer and inflammatory colon disease.

Christoph Alexander Ausch, Simone Zotter, Maidah Scheikh, Heike Bauer, Marina Mollik, Erika Bajna, Christian Sebesta, Angelika Reiner, Theresia Thalhammer and Veronika Buxhofer-Ausch

Journal of Clinical Oncology (American Society of Clinical Oncology) , 20 January 2014

Oncology

Key words: Prostaglandins, cyclic nucleotides, second messenger proteins, tumor cells growth

A dual role for autophagy in a murine model of lung cancer

Shuan Rao, Luigi Tortola, Thomas Perlot, Gerald Wirnsberger, Maria Novatchkova, Roberto Nitsch, Peter Sykacek, Lukas Frank, Daniel Schramek, Vukoslav Komnenovic, Verena Sigl, Karin Aumayr, Gerald Schmauss, Nicole Fellner, Stephan Handschuh, Martin Glösmann, Pawel Pasierbek, Michaela Schlederer, Guenter P Resch, Yuting Ma, Heng Yang, Helmuth Popper, Lukas Kenner, Guido Kroemer and Josef M Penninger

Nature Communications (Nature) Austria, France, 20 January 2014

Oncology

Key words: Autophagy, Lung cancer, Oncogenesis [more]

Glycogen Synthase Kinase 3β (GSK3β) Regulates Differentiation and Proliferation in Neural Stem Cells from the Rat Subventricular Zone 1

Martin H Maurer, Jens O Brömme, Robert E Feldmann, Jr Anne Järve, Fatemeh Sabouri, Heinrich F Bürgers, Dominik W Schelshorn, Carola Krüger, Armin Schneider, Wolfgang Kuschinsky

Journal of Proteome Research (ACS Publications) Germany, 18 January 2014

Stem Cell Research

Key words: Neural stem cell, Neurosphere, Glycogen Synthase Kinase 3β, Two-dimensional gel electrophoresis, Rat, Subventricular zone [more]

NF-E2-related factor 2 promotes compensatory liver hypertrophy after portal vein branch ligation in mice

Keiichi Shirasaki, Keiko Taguchi, Michiaki Unno, Hozumi Motohashi, Masayuki Yamamoto

Hepatology (Wiley) Japan, 17 January 2014

Hepathology

Key words: Hepatectomy, portal vein embolization, phosphoinositide 3-kinase, protein kinase B (PI3K/Akt) pathway [more]

Hepatic RIG-I Predicts Survival and Interferon-α Therapeutic Response in Hepatocellular Carcinoma

Jin Hou, Ye Zhou, Yuanyuan Zheng, Jia Fan, Weiping Zhou, Irene OL Ng, Huichuan Sun, Lunxiu Qin, Shuangjian Qiu, Joyce MF Lee, Chung-Mau Lo, Kwan Man, Yuan Yang, Yun Yang, Yingyun Yang, Qian Zhang, Xuhui Zhu, Nan Li, Zhengxin Wang, Guoshan Ding, Shi-Mei Zhuang, Limin Zheng, Xiaoling Luo, Yuan Xie, Anmin Liang, Zhugang Wang, Ming Zhang, Qiang Xia, Tingbo Liang, Yizhi Yu, Xuetao Cao

Cancer Cell (Cell Press) China, 13 January 2014

Oncology

Key words: Hepatocellular carcinoma, interferon-α, retinoic acid-inducible gene-I [more]