Customer Publications (A total of 2116 papers published)

The role of cytokines and chemokines in the T-cell-mediated autoimmune process in alopecia areata

Taisuke Ito, Yoshiki Tokura

Experimental Dermatology (Wiley) Japan, 29 October 2014

Dermatology

Key words: Alopecia areata, chemokine, cytokine, immune privilege, swarm of bees [more]

Megakaryocytes are essential for HSC quiescence through the production of thrombopoietin

Ayako Nakamura-Ishizua, Keiyo Takubo, Masato Fujioka, Toshio Suda

Biochemical and Biophysical Research Communications (Elsevier) Japan, 24 October 2014

Hematology

Key words: Megakaryocytes, hematopoietic stem cells, thrombopoietin, niche, bone marrow [more]

Fenretinide: A Novel Treatment for Endometrial Cancer

Navdha Mittal, Saurabh Malpani, Matthew Dyson, Masanori Ono, John S Coon, Julie J Kim, Julian C Schink, Serdar E Bulun, Mary Ellen Pavone

PLoS One (PLOS) USA, 23 October 2014

Oncology

Key words: Cancer treatment, apoptosis, uterine cancer, vitamin A, gene expression, small interfering RNAs, retinoic acid, cancer therapy [more]

Loss of Gsα Early in the Osteoblast Lineage Favors Adipogenic Differentiation of Mesenchymal Progenitors and Committed Osteoblast Precursors

Partha Sinha, Piia Aarnisalo, Rhiannon Chubb, Noriaki Ono, Keertik Fulzele, Martin Selig, Hamid Saeed, Min Chen, Lee S Weinstein, Paola Divieti Pajevic, Henry M Kronenberg, Joy Y Wu

Journal of Bone and Mineral Research (Wiley) USA, Finland, 20 October 2014

Rheumatology

Key words: Osteoblasts, GSA, mesenchymal progenitors, adipocytes [more]

Role of fractalkine in the pathogenesis of primary Sjögren syndrome: increased serum levels of fractalkine, its expression in labial salivary glands, and the association with clinical manifestations

Jae Ho Lee, Seung-Ki Kwok, Seung Min Jung, Jennifer Lee, Jae-Seon Lee, Seung Ye Baek, Eun-Kyung Kim, Ji Hyeon Ju, Sung-Hwan Park and Ho-Youn Kim

Journal of Rheumatology (jrheum.org) South Korea, 15 October 2014

Rheumatology

Key words: SJÖGREN SYNDROME, FRACTALKINE, CX3CR1 [more]

Langerhans cells promote early germinal center formation in response to Leishmania-derived cutaneous antigens

Nicole Zimara, Christian Florian, Maximilian Schmid, Bernard Malissen, Adrien Kissenpfennig, Daniela N Männel, Matthias Edinger, James A Hutchinson, Petra Hoffmann, Uwe Ritter

European Journal of Immunology (Wiley) Germany, France, UK, 13 October 2014

Immunology

Key words: B cells, follicular helper, germinal center reaction, langerhans cells, leishmania major, T cells [more]

The pre- and post-somatic segments of the human type I spiral ganglion neurons – Structural and functional considerations related to cochlear implantation

W Liu, F Edin, F Atturo, G Rieger, H Löwenheime, P Senn, M Blumer, A Schrott-Fischer, H Rask-Andersen, R Glueckert

Neuroscience (Elsevier) Sweden, Italy, Austria, Germany, Switzerland, 12 October 2014

Neuroscience

Key words: Human cochlea, spiral ganglion neurons, non-myelinated Schwann cells, laminin-ß2, collagen IV, immunohistochemistry [more]

Specific expression of OATPs in primary small cell lung cancer (SCLC) cells as novel biomarkers for diagnosis and therapy

Stefan Brenner, Lukas Klameth, d, Juliane Riha, Madeleine Schölm, Gerhard Hamilton, Erika Bajna, Christoph Ausch, Angelika Reiner, Walter Jäger, Theresia Thalhammer , Veronika Buxhofer-Ausch

Cancer Letters (Elsevier) Austria, 06 October 2014

Oncology

Key words: Small cell lung cancer (SCLC), organic anion transporting polypeptide (OATP), neurogenic marker, chemotherapy, OATP gene expression [more]

TGF-β is an inducer of ZEB1-dependent mesenchymal transdifferentiation in glioblastoma that is associated with tumor invasion

JV Joseph, S Conroy, T Tomar, E Eggens-Meijer, K Bhat, S Copray, AME Walenkamp, E Boddeke, V Balasubramanyian, M Wagemakers, WFA den Dunnen and FAE Kruyt

Cell Death & Disease (Nature) The Netherlands, USA, 02 October 2014

Oncology

Key words: Cell signalling, CNS cancer, Transdifferentiation, Transforming growth factor beta [more]

Adipose tissue–derived stromal cells inhibit TGF-β1–induced differentiation of human dermal fibroblasts and keloid scar–derived fibroblasts in a paracrine fashion

M Spiekman, E Przybyt, JA Plantinga, S Gibbs,B van der Lei, M Harmsen

Plastic and Reconstructive Surgery (Wolters Kluwer) The Netherlands, 01 October 2014

Stem Cell Research

[more]

The Inner Foreskin of Healthy Males at Risk of HIV Infection Harbors Epithelial CD4+ CCR5+ Cells and Has Features of an Inflamed Epidermal Barrier

Maria P Lemos, Javier R Lama, Shelly T Karuna, Youyi Fong, Silvia M Montano, Carmela Ganoza, Raphael Gottardo, Jorge Sanchez, M Juliana McElrath

PLoS One (PLOS) USA, Peru, 30 September 2014

Virology

Key words: Epidermis, inflammation, membrane staining, epithelium, keratinocytes, HIV infections, circumcision HIV [more]

Late effects of local irradiation on the expression of inflammatory markers in the Arteria saphena of C57BL/6 wild-type and ApoE-knockout mice

I Patties, B Habelt, B Rosin, W Dörr, G Hildebrandt, A Glasow

Radiation and Environmental Biophysiscs (Springer) Germany, Austria, 27 September 2014

Immunology

Key words: A. saphe , inflammation, irradiatin , ApoE-knockout mice, atherosclerosis, macrovasculature [more]

CCR9/CCL25 expression in non-small cell lung cancer correlates with aggressive disease and mediates key steps of metastasis

Pranav Gupta, Praveen K Sharma, Hina Mir, Rajesh Singh, Nalinaksha Singh, Goetz H Kloecker, James W Lillard, and Shailesh Singh

Oncotarget (Impact Journals) USA, India, 25 September 2014

Oncology

Key words: CCR9, CCL25, Chemokine receptor, Non-small cell lung cancer [more]

Extracellular matrix components of adipose derived stromal cells promote alignment, organization, and maturation of cardiomyocytes in vitro

Ewa Przybyt, Marja J A van Luyn andMartin C Harmsen

Journal of Biomedical Materials Research (Wiley) The Netherlands, 24 September 2014

Transplantation Medicine

Key words: Myocardial infarction, cardiomyocytes, adipose derived stromal cells, extracellular matrix [more]

Myeloid-derived suppressor cell functionality and interaction with Leishmania major parasites differ in C57BL/6 and BALB/c mice

Maximilian Schmid, Nicole Zimara, Anja Kathrin Wege, Uwe Ritter

European Journal of Immunology (Wiley) Germany, 19 September 2014

Immunology

Key words: Arginase-1, bone marrow, inducible nitric oxide synthase, leishmania major, myeloid-derived suppressor cells [more]

Intratracheal administration of influenza virus is superior to intranasal administration as a model of acute lung injury

Luisa Morales-Nebreda, Monica Chi, Emilia Lecuona, Navdeep S Chandel, Laura A Dada, Karen Ridge, Saul Soberanes, Recep Nigdelioglu, Jacob I Sznajder, Gökhan M Mutlu, GR Scott Budinger, Kathryn A Radigan

Journal of Virological Methods (Elsevier) USA, 17 September 2014

Virology

Key words: Influenza A infection, inoculation, mice, lung injury, intratracheal, intranasal [more]

Antigen-loaded dendritic cell migration: MR imaging in a pancreatic carcinoma model

Zhuoli Zhang , Weiguo Li, Daniele Procissi, Kangan Li, Alexander Y Sheu, Andrew C Gordon, Yang Guo, Khashayarsha Khazaie, Yi Huan, Guohong Han, Andrew C Larson

Radiology (Radiological Society of North America) China, 15 September 2014

Oncology

[more]

Role of TRAP1 and estrogen receptor alpha in patients with ovarian cancer -A study of the OVCAD consortium

Stefanie Aust, Anna Bachmayr-Heyda, Petra Pateisky, Dan Tong, Silvia Darb-Esfahani, Carsten Denkert, Radoslav Chekerov, Jalid Sehouli, Sven Mahner, Toon Van Gorp, Ignace Vergote, Paul Speiser, Reinhard Horvat, Robert Zeillinger, Dietmar Pils

Molecular Cancer (Springer) Austria, Germany, Belgium, The Netherlands, 14 September 2014

Oncology

Key words: TRAP1, estrogen receptorImmunohistochemistry, prognosis, ovarian cancer [more]

Specific roles for dendritic cell subsets during initiation and progression of psoriasis

Elisabeth Glitzner, Ana Korosec, Patrick M Brunner, Barbara Drobits, Nicole Amberg, Helia B Schonthaler, Tamara Kopp, Erwin F Wagner, Georg Stingl, Martin Holcmann,Maria Sibilia

EMBO Molecular Medicine (EMBO press) Austria, Spain, 12 September 2014

Dermatology

Key words: AP-1, IL-23, langerhans cells, plasmacytoid dendritic cells, psoriasis [more]

An Activatable Prodrug for the Treatment of Metastatic Tumors

Eun-Joong Kim, Sankarprasad Bhuniya, Hyunseung Lee, Hyun Min Kim, Chaejoon Cheong, Sukhendu Maiti, Kwan Soo Hong, Jong Seung Kim

Journal of the American Chemical Society (ACS Publications) South Korea, 11 September 2014

Oncology

Key words: Metastatic cancers, tumor cell growth, cellular imaging [more]

Olfactory Receptor Patterning in a Higher Primate

Lisa F Horowitz, Luis R Saraiva, Donghui Kuang, Kyoung-hye Yoon, Linda B Buck

Journal of Neuroscience (SFN) USA, 10 September 2014

Neuroscience

Key words: Macaque odorant receptor, primate trace-amine associated receptor [more]

Late inflammatory and thrombotic changes in irradiated hearts of C57BL/6 wild-type and atherosclerosis-prone ApoE-deficient mice

I Patties, J Haagen, W Dörr, G Hildebrandt, A Glasow

Strahlentherapie und Onkologie (Springer) Germany, Austria, 09 September 2014

Radiotherapy

Key words: Irradiatio, n microvasculature, Heart Inflammation, Atheroscrosis Bestrahlung, Mikrovaskulatur, Herz Entzündung Atherosklerose [more]

Energy metabolism analysis reveals the mechanism of inhibition of breast cancer cell metastasis by PEG-modified graphene oxide nanosheets

Teng Zhoua, Bo Zhang, Peng Wei,Yipeng Du, Hejiang Zhou, Meifang Yu, Liang Yan, Wendi Zhang, Guangjun Nie, Chunying Chen, Yaping Tu, Taotao Wei

Biomaterials (Elsevier) China, USA, 08 September 2014

Nanomedicine

Key words: PEG-modified graphene oxide, breast cancer cell, metastasis, cytoskeletal assembly, mitochondrial oxidative phosphorylation [more]

STAT3β controls inflammatory responses and early tumor onset in skin and colon experimental cancer models

Francesca Marino, Valeria Orecchia, Gabriella Regis, Monica Musteanu, Beatrice Tassone, Cristina Jon, Marco Forni, Enzo Calautti, Roberto Chiarle, Robert Eferl, and Valeria Poli

American Journal of Cancer Research (NCBI) Italy, Austria, Spain, USA, 06 September 2014

Oncology

Key words: STAT3 isoforms, STAT3β, inflammation, inflammation-driven tumorigenesis, colitis-associated cancer, AOM/DSS protocol, skin tumorigenesis, DMBA/TPA protocol, genetically modified mice [more]

Optimisation of the quantitative analysis of inflammatory cell infiltrates in breast cancer/Optimizarea analizei cantitative a infiltratului celular inflamator în cancerul …

AR Vrânceanu, CC Tărniceriu, D Jitaru, C Terinte, F Zugun-Eloae, E Carasevici

Revista Romana de Medicina de Laborator () Romania, 03 September 2014

Oncology

[more]

NEW INSIGHTS IN PULMONARY HYPERTENSION

European Heart Journal (Oxford University Press) Italy, 31 August 2014

Cardiology

Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix

Leila Akkari, Vasilena Gocheva, Jemila C Kester, Karen E Hunter, Marsha L Quick, Lisa Sevenich, Hao-Wei Wang, Christoph Peters, Laura H Tang, David S Klimstra, Thomas Reinheckel, Johanna A Joyce

Genes and Development (CSH Press) USA, Germany, 29 August 2014

Oncology

Key words: Cell invasion, cell migration, tumor microenvironment protease [more]

Quantitative LA-ICP-MS imaging of platinum in chemotherapy treated human malignant pleural mesothelioma samples using printed patterns as standard

M Bonta, H Lohninger, V Laszlo, B Hegedus, A Limbeck

Journal of Analytical Atomic Spectrometry (Royal Society of Chemistry) Austria, Hungary, 29 August 2014

Oncology

[more]

Macrophage Migration Inhibitory Factor Triggers Chemotaxis of CD74+CXCR2+ NKT Cells in Chemically Induced IFN-γ–Mediated Skin Inflammation

Chia-Yuan Hsi, Chia-Ling Chen, Yee-Shin Lin, Trai-Ming Yeh, Tsung-Ting Tsai, Ming-Yuan Hong, Chiou-Feng Lin

The Journal of Immunology (American Association of Immunologists) Taiwan, 29 August 2014

Immunology

Key words: Human NK cell, macrophage migration inhibitory factor [more]

Vascularization of primary and secondary ossification centres in the human growth plate

Sonja M Walzer, Erdal Cetin, Ruth Grübl-Barabas, Irene Sulzbacher, Beate Rueger, Werner Girsch, Stefan Toegel, Reinhard Windhager, Michael B Fischer

BMC Developmental Biology (Springer) Austria, 28 August 2014

Developmental Biology

Key words: Growth plate, vascularization, primary ossification centres, secondary ossification centres, progenitor cells [more]

Type I interferons have opposing effects during the emergence and recovery phases of colitis

Isabella Rauch, Eva Hainzl, Felix Rosebrock, Susanne Heider, Clarissa Schwab, David Berry, Dagmar Stoiber, Michael Wagner, Christa Schleper, Alexander Loy, Tim Urich, Mathias Müller, Birgit Strobl, Lukas Kenner,Thomas Decker

European Journal of Immunology (Wiley) Austria, 25 August 2014

Immunology

Key words: Colitis, inflammation, interferons, interleukin-1, microbiota [more]

Shock Wave Treatment Enhances Cell Proliferation and Improves Wound Healing by ATP Release-coupled Extracellular Signal-regulated Kinase (ERK) Activation

Anna M Weihs, Christiane Fuchs, Andreas H Teusch, Joachim Hartinger, Paul Slezak, Rainer Mittermayr, Heinz Redl§,Wolfgang G Junger, Harald H Sitte, Dominik Rünzler

Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) Austria, 12 August 2014

Regenerative Medicine

Key words: ATP Cell proliferation, extracellular signal-regulated kinase (ERK), signal transduction, wound healing, shock wave treatment [more]

Histological Characterization and Quantification of Cellular Events Following Neural and Fibroblast(-Like) Stem Cell Grafting in Healthy and Demyelinated CNS Tissue

Jelle Praet, Eva Santermans, Kristien Reekmans, Nathalie de Vocht, Debbie Le Blon, Chloé Hoornaert, Jasmijn Daans, Herman Goossens, Zwi Berneman, Niel Hens, Annemie Van der Linden, Peter Ponsaert

Animal Models for Stem Cell Therapy (Springer) Belgium, 04 August 2014

Stem Cell Research

Key words: Neural stem cell, mouse embryonic fibroblasts, cell grafting, cuprizone, quantitative histology, inflammation

Analysis of tumour-and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S

Lisa Sevenich, Robert L Bowman, Steven D Mason, Daniela F Quail, Franck Rapaport, Benelita T Elie, Edi Brogi, Priscilla K Brastianos, William C Hahn, Leslie J Holsinger, Joan Massagué, Christina S Leslie and Johanna A Joyce

Nature Cell Biology (Nature) USA, 03 August 2014

Oncology

Key words: Cancer microenvironment, Metastasis [more]

Benzyl butyl phthalate induces migration, invasion, and angiogenesis of Huh7 hepatocellular carcinoma cells through nongenomic AhR/G-protein signaling

Cheng-Fang Tsai, Tsung-Hua Hsieh, Jau-Nan Lee, Chia-Yi Hsu, Yu-Chih Wang, Feng-Jie Lai, Kung-Kai Kuo, Hua-Lin Wu, Eing-Mei Tsai and Po-Lin Kuo

BMC Cancer (Springer) Taiwan, 01 August 2014

Oncology

Key words: Phthalate, Aryl hydrocarbon receptor, Angiogenesis, Migration, Hepatocellular carcinoma [more]

The vitamin D system is deregulated in pancreatic diseases

Doris Hummel, Abhishek Aggarwal, Katalin Borka, Erika Bajna, Enikö Kállay, Henrik Csaba Horváth

The Journal of Steroid Biochemistry and Molecular Biology (Elsevier) Austria, Hungary, Switzerland, 30 July 2014

Oncology

Key words: Vitamin D, CYP24A1, VDR, CaSR, chronic pancreatitis, pancreatic ductal adenocarcinoma, pancreatic cancer [more]

Hardware and Software

Yves Sucaet, Wim Waelput

Hardware and Software (Springer) Belgium, 23 July 2014

Medical Imaging

Key words: Digital pathology, slide scanner, tile scanner, line scanner, file format, medical imaging WSI DP MRXS NDPI SVS BIF

Single Administration of p2TA (AB103), a CD28 Antagonist Peptide, Prevents Inflammatory and Thrombotic Reactions and Protects against Gastrointestinal Injury in Total-Body Irradiated Mice

Salida Mirzoeva, Tatjana Paunesku, M Beau Wanzer, Anat Shirvan, Raymond Kaempfer, Gayle E Woloschak, William Small Jr

PLoS One (PLOS) USA, Israel, 23 July 2014

Gastroenterology

Key words: Inflammation, ayclins, fibrinogen, macrophages, gamma rays, cytokines, infrared radiation, small intestine [more]

Absence of substance P and the sympathetic nervous system impact on bone structure and chondrocyte differentiation in an adult model of endochondral ossification

Tanja Niedermaira, Volker Kuhn, Fatemeh Doranehgard, Richard Stange, Britta Wieskötter, Johannes Beckmann, Philipp Salmen, Hans-Robert Springorum, Rainer H Straub, Andreas Zimmer, Joachim Grifka, Susanne Grässel

Matrix Biology (Elsevier) Germany, Austria, 22 July 2014

Neuroscience

Key words: Substance P, sympathetic nerve fibers, fracture callus, bone structure, bone formation, bone resorption, biomechanics, endochondral ossification [more]

Wnt Coreceptor Lrp5 Is a Driver of Idiopathic Pulmonary Fibrosis

Anna P Lam , Jose D Herazo-Maya , Joseph A Sennello , Annette S Flozak , Susan Russell , Gökhan M Mutlu , G R Scott Budinger , Ramanuj DasGupta , John Varga , Naftali Kaminski , and Cara J Gottardi

American Journal of Respiratory and Critical Care Medicine (ATS Journals) USA, 15 July 2014

Pulmonology

Key words: lung fibrosis, Wnt/β-catenin signaling, peripheral blood mononuclear cell [more]

Reliable Quantification of Protein Expression and Cellular Localization in Histological Sections

Michaela Schlederer, Kristina M Mueller, Johannes Haybaeck, Susanne Heider, Nicole Huttary, Margit Rosner, Markus Hengstschläger, Richard Moriggl, Helmut Dolznig, Lukas Kenner

PLoS One (PLOS) Austria, 11 July 2014

Pathology

Key words: Image analysis, pathologists, cell staining, hepatocytes, protein expression, cytoplasmic staining, transcription factors, hepatocellular carcinoma [more]

EpCAM is overexpressed in local and metastatic prostate cancer, suppressed by chemotherapy and modulated by MET-associated miRNA-200c/205

P Massoner, T Thomm, B Mack, G Untergasser, A Martowicz, K Bobowski, H Klocker, O Gires and M Puhr

British Journal of Cancer (Nature) Austria, Germany, 03 July 2014

Oncology

Key words: Biomarkers, Cancer therapeutic resistance, Oncogenesis, Prostate cancer [more]

Alteration in the Wnt microenvironment directly regulates molecular events leading to pulmonary senescence

Tamas Kovacs, Veronika Csongei, Diana Feller, David Ernszt, Gabor Smuk, Veronika Sarosi, Laszlo Jakab, Krisztian Kvell, Domokos Bartis Judit E Pongracz

Aging Cell (Wiley) Hungary, UK, 01 July 2014

Cell Biology

Key words: Molecular biology of aging, pulmonary senescence, Wnt microenvironment [more]

Distinct spatial distribution of microglia and macrophages following mesenchymal stem cell implantation in mouse brain

Debbie Le Blon, Chloé Hoornaert, Jasmijn Daans, Eva Santermans, Niel Hens, Herman Goossens, Zwi Berneman, Peter Ponsaerts

Immunology and Cell Biology (Wiley) Belgium, 01 July 2014

Immunology

[more]

Comprehensive assessment of HIV target cells in the distal human gut suggests increasing HIV susceptibility toward the anus

MJ McElrath, K Smythe, J Randolph-Habecker, KR Melton, TA Goodpaster, S Hughes, M Mack, A Sato, G Diaz, G Steinbach, R Novak, M Curlin, JD Lord, J Maenza, A Duerr, N Frahm, F Hladik

Journal of acquired immune deficiency Syndrome (NCBI) USA, Germany, 01 July 2014

Virology

[more]

Podocalyxin-like 1 promotes invadopodia formation and metastasis through activation of Rac1/Cdc42/cortactin signaling in breast cancer cells

Cheng-Wei Lin, Min-Shiou Sun, Mei-Ying Liao, Chu-Hung Chung, Yi-Hsuan Chi, Li-Tin Chiou, John Yu, Kuo-Lung Lou, Han-Chung Wu

Carcinogenesis (Oxford University Press) Taiwan, 26 June 2014

Oncology

Key words: Podocalyxin-like 1 invadopodia, cortactin invasion metastasis [more]

Memantine Alleviates Brain Injury and Neurobehavioral Deficits after Experimental Subarachnoid Hemorrhage

Chih-Yuan Huang, Liang-Chao Wang, Hao-Kuang Wang, Chia-Hsin Pan, Ya-Yun Cheng, Yan-Shen Shan, Chung-Ching Chio, Kuen-Jer Tsai

Molecular Neurobiology (Springer) Taiwan, 22 June 2014

Neuroscience

Key words: Blood-brain barrier, memantine, neuroprotection, nitric oxide synthase, subarachnoid hemorrhage [more]

OP0103 Decreased Lupus Severity in Mir155 Deficient Mice

H Leiss, W Salzberger, I Gessl, N Kozakowski, S Blüml, A Puchner, B Niederreiter, G Steiner, J Smolen, G Stummvoll

Annals of the Rheumatic Diseases (BMJ Journals) Austria, 14 June 2014

Rheumatology

Key words: MicroRNAs, MiR155-deficient, glomerulonephritis, serum antibody, T helper cell homeostasis [more]

OP0300 Effect of VEGF121-Fibrin on the Expression of VEGF Receptors in Ischemic Lesions of UCD-206 Chickens, an Animal Model for Systemic Sclerosis

S Allipour-Birgani, H Dietrich, J Gruber, O Distler, A Zisch, R Sgonc

Annals of the Rheumatic Diseases (BMJ Journals) Austria, Switzerland, 14 June 2014

Rheumatology

Key words: Systemic sclerosis, perivascular mononuclear cell infiltration, Microvascular injury, angiogenesis, vascular endothelial cell growth factor [more]

An integrated approach for the systematic evaluation of polymeric nanoparticles in healthy and diseased organisms

Leopoldo Sitia, Katia Paolella, Michela Romano, Martina Bruna Violatto, Raffaele Ferrari, Stefano Fumagalli, Laura Colombo, Ezia Bello, Maria Grazia De Simoni, Maurizio D’Incalci, Massimo Morbidelli, Eugenio Erba, Mario Salmona, Davide Moscatelli, Paolo Bigini

Journal of Nanoparticle Research (Springer) Italy, Switzerland, 12 June 2014

Nanomedicine

Key words: Optical imaging, cellular uptake, protein corona, breast tumor, cell cycle phase, nu nu mouse, atomic force microscopy, lymph node, involvment, intracellular delivery, tumor vasculature [more]

A hormone-dependent feedback-loop controls androgen receptor levels by limiting MID1, a novel translation enhancer and promoter of oncogenic signaling

Andrea Köhler, Ümmühan Demir, Eva Kickstein, Sybille Krauss, Johanna Aigner, Beatriz Aranda-Orgillés, Antonios I Karagiannidis, Clemens Achmüller, Huajie Bu, Andrea Wunderlich, Michal-Ruth Schweiger, Georg Schaefer, Susann Schweiger, Helmut Klocker, Rainer Schneider

Molecular Cancer (Springer) Austria, Germany, UK, 09 June 2014

Oncology

Key words: Androgen receptor, MID1, Translation, Prostate cancer, Reciprocal regulation [more]

B Cells and Ectopic Follicular Structures: Novel Players in Anti-Tumor Programming with Prognostic Power for Patients with Metastatic Colorectal Cancer

Anastasia Meshcheryakova, Dietmar Tamandl, Erika Bajna, Judith Stift, Martina Mittlboeck, Martin Svoboda, Denise Heiden, Stefan Stremitzer, Erika Jensen-Jarolim, Thomas Grünberger, Michael Bergmann, Diana Mechtcheriakova

PLoS One (PLOS) Austria, 06 June 2014

Immunology

Key words: B cells, immune cells, macrophages, cell staining, portal veins, colorectal cancer, DAPI staining, nuclear staining [more]

Angiogenesis as prospective molecular biology technique for cancer study

Grigore T Popa

Romanian Biotechnological Letters (University of Bucharest) Romania, 03 June 2014

Oncology

Key words: esophagus, tumor, neoangiogenesis, quantitative study [more]

Circulating Cytokines and Alarmins Associated with Placental Inflammation in High-Risk Pregnancies

Sylvie Girard, Alexander E P Heazell, Hayley Derricott, Stuart M Allan, Colin P Sibley, Vikki M Abrahams, Rebecca L Jones

American Journal of Reproductive Immunology (Wiley) UK, USA, Canada, 28 May 2014

Reproductive Medicine

Key words: High-risk pregnancy, inflammation, placental dysfunction, stillbirth [more]

A novel rat full-thickness hemi-abdominal wall/hindlimb osteomyocutaneous combined flap: influence of allograft mass and vascularized bone marrow content on vascularized composite allograft survival

Alejandro E Ramirez, Hui-Yun Cheng3, William W Lao, Yen-Ling Wang, Chih-Jen Wen, Christopher G Wallace, Chih-Fan Lin, Ling-Yi Shih, Sheng-Hao Chuang and Fu-Chan Wei

Transplant International (Wiley) Taiwan, Chile, USA, 24 May 2014

Transplantation Medicine

Key words: Abdominal wall transplantation, allograft mass, allograft survival, combined flap, vascularized bone marrow, vascularized composite allotransplantation [more]

Coexpression of CD44-positive/CD133-positive cancer stem cells and CD204-positive tumor-associated macrophages is a predictor of survival in pancreatic ductal adenocarcinoma

Ya-Chin Hou, Ying-Jui Chao, Hui-Ling Tung, Hao-Chen Wang, Yan-Shen Shan

Cancer (Wiley) Taiwan, 19 May 2014

Oncology

Key words: Pancreatic ductal adenocarcinoma, cancer stem cells, tumor-associated macrophages, tissue microarrays, CD44, CD133, CD204 [more]

Cav3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage

Shin-Shiou Lin, Bing-Hsiean Tzeng,Kuan-Rong Lee, Richard J H Smith, Kevin P Campbell, Chien-Chang Chen

PNAS (PNAS) Taiwan, USA, 13 May 2014

Physiology

Key words: Chondrogenesis, tracheal cartilage, mesenchymal cells, chondrocytes [more]

Cell cycle association and hypoxia regulation of excision repair cross complementation group 1 protein (ERCC1) in tumor cells of head and neck cancer

József Dudás, Volker H Schartinger, Angela Romani, Gabriele Schweigl, Kristian Kordsmeyer, Patricia Irina Marta, Christoph Url, Florian Kral, Herbert Riechelmann

Tumor Biology (Springer) Austria, 12 May 2014

Oncology

Key words: Gene expression, cell cycle phase, bronchial epithelial cell, nuclear extract [more]

Relevance of estrogen activating STS and inactivating SULT1E1 enzymes and estrogen receptors [alpha/beta] in patients with advanced ovarian cancer

Felicitas Mungenast, Stefanie Aust, Martin Svoboda, Katharina Ocko, Lukas Klameth, Dan Cacsire Castilo-Tong, Robert Zeillinger, Toon Van Gorp, Ignace Vergote, Ioana Braicu, Jalid Sehouli, Sven Mahner, M Fogel and Theresia Thalhammer

16th European Congress of Endocrinology (Endocrine Abstracts) Austria, Belgium, Germany, Israel, 07 May 2014

Oncology

A new rat model for orthotopic abdominal wall allotransplantation

WW Lao, YL Wang, AE Ramirez, HY Cheng, FC Wie

Plastic Reconstruction Surgery Global open (NCBI) Taiwan, 07 May 2014

Oncology

[more]

1172 (pp34) myocardial Biopsy for the Validation of Cardiac Magnetic Resonance T1 Mapping for Quantification of Extracellular Matrix

A Kammerlander, C Tufaro, S Pfaffenberger, B Marzluf, S Aschauer, J Babayev, D Bonderman, J Mascherbauer

European Heart Journal (Oxford University Press) Austria, 01 May 2014

Cardiology

[more]

A new fluorescence/PET probe for intracellular human telomerase reverse transcriptase (hTERT) using Tat peptide-conjugated antibody

Kyung Oh Jung, Hyewon Youn, Mi Jeong Kim, Keon Wook Kang, Dong Soo Lee and June-Key Chung

The Journal of Nuclear Medicine () South Korea, 01 May 2014

Biological Methods

[more]

Increase of Zinc Finger Protein 179 in Response to CCAAT/Enhancer Binding Protein Delta Conferring an Antiapoptotic Effect in Astrocytes of Alzheimer’s Disease

Shao-Ming Wang, Yi-Chao Lee, Chiung-Yuan Ko, Ming-Derg Lai, Ding-Yen Lin, Ping-Chieh Pao, Jhih-Ying Chi, Yu-Wei Hsiao, Tsung-Lin Liu, Ju-Ming Wang

Molecular Neurobiology (Springer) Taiwan, 01 May 2014

Neuroscience

Key words: Alzheimer's disease CEBPD ZNF179, astrocytes, antiapoptosis [more]

PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors

Rieko Ohki, Kozue Saito, Yu Chen, Tatsuya Kawase, Nobuyoshi Hiraoka, Raira Saigawa, Maiko Minegishi, Yukie Aita, Goichi Yanai, Hiroko Shimizu, Shinichi Yachida, Naoaki Sakata, Ryuichiro Doi, Tomoo Kosugi, Kazuaki Shimada, Benjamin Tycko, Toshihiko Tsukada, Yae Kanai, Shoichiro Sumi, Hideo Namiki, Yoichi Taya, Tatsuhiro Shibata, Hitoshi Nakagama

PNAS (PNAS) Japan, 01 May 2014

Oncology

Key words: p53 PH domain everolimus p53 target gene mTOR [more]

ISAC XXII International Congress

ISAC XXII International Congress

Cytometry Part A (Wiley) , 21 April 2014

Cytometry

Epicutaneously applied Der p 2 induces a strong TH2-biased antibody response in C57BL/6 mice, independent of functional TLR4

C Stremnitzer, K Manzano-Szalai, P Starkl, A Willensdorfer, S Schrom, J Singer, U Reichart, S Akira, E Jensen-Jarolim

Allergy (Wiley) Austria, 16 April 2014

Allergy Research

Key words: Allergic dermatitis, Der p 2, house dust mite, LPS, TLR4 [more]

Direct comparison of the dynamics of IL-25- and ‘allergen’-induced airways inflammation, remodelling and hypersensitivity in a murine asthma model

X J Yao, K W Huang, Y Li, Q Zhang, J J Wang, W Wang, J Liu, Z Lv, Y Q An, Y Z Ding, C J Corrigan, W Wang, Y C Sun, S Ying

Clinical and Experimental Allergy (Wiley) China, UK, 16 April 2014

Allergy Research

Key words: Asthma, IL-25, IL-25 receptor, murine model, pathogenesis, remodelling [more]

Poly(lactide-co-glycolide) microspheres for MRI-monitored transcatheter delivery of sorafenib to liver tumors

Jeane Chen, Alexander Y Sheu, Weiguo Li, Zhuoli Zhang, c, Dong-Hyun Kim, Robert J Lewandowski, Reed A Omary, Lonnie D Shea, Andrew C Larson

Journal of Controlled Release (Elsevier) USA, 13 April 2014

Oncology

Key words: Sorafenib, hepatocellular carcinoma, magnetic resonance imaging, poly(lactide-co-glycolide) [more]

Abstract 1662: Towards automated analysis of prostate inflammatory state: Assessing density and distance of infiltrating T-cells (CD3+) to glandular structures in prostate biopsies by a new software

Radu Rogojanu, Bogdan Boghiu, Georg Schaefer, Theresia Thalhammer, Georg Steiner, Rupert Ecker, Bettina Schlick, Thomas Szekeres, Isabella Ellinger

Cancer Research (AACR Publications) Austria, Romania, 09 April 2014

Medical Image Analysis

Key words: Biopsies, automated analysis [more]

T cell-associated α4β7 but not α4β1 integrin is required for the induction and perpetuation of chronic colitis

E Kurmaeva, JD Lord, S Zhang, JR Bao, CG Kevil, MB Grisham and DV Ostanin

Mucosal Immunology (Nature) USA, 09 April 2014

Immunology

Key words: Antibody therapy, Colitis, Crohn's disease, Mucosal immunology [more]

Calcium-sensing receptor silencing in colorectal cancer is associated with promoter hypermethylation and loss of acetylation on histone 3

Irfete S Fetahu, Julia Höbaus, Abhishek Aggarwal, Doris M Hummel, Samawansha Tennakoon, Ildiko Mesteri, Sabina Baumgartner-Parzer, Eniko Kállay

International Journal of Cancer (Wiley) Austria, 02 April 2014

Oncology

Key words: Calcium-sensing receptor, DNA methylation, histone acetylation, histone methylation, colorectal cancer [more]

Oncogenic functions of IGF1R and INSR in prostate cancer include enhanced tumor growth, cell migration and angiogenesis

I Heidegger, J Kern, P Ofer, H Klocker, P Massoner

Oncotarget (Impact Journals) Austria, 02 April 2014

Oncology

Key words: Prostate cancer, IGF targeting therapies, insulin-like growth factor receptor-1 (IGF1R), insulin receptor (INSR) [more]

Transplantation of cyclic stretched fibroblasts accelerates the wound-healing process in streptozotocin-induced diabetic mice

E Lee, DY Kim, E Chung, EA Lee, KS Park, Y Son

Cell Transplantation (SAGE Journals) South Korea, 01 April 2014

Transplantation Medicine

Key words: Cell survival, Cyclic stretch, Mechanical stimulus, Angiogenesis, Wound healing [more]

Protective effect of magnesium and metformin on endometrium and ovary in experimental diabetes mellitus

C Gales, C Zamfir, D Radulescu, B Stoica, M Nechifor

Magnesium research (John Libbey) Romania, 01 April 2014

Reproductive Medicine

Key words: magnesium, endometrium, ovary, diabetes mellitus [more]

Muscle–fat MRI: 1.5 tesla and 3.0 tesla versus histology

Andrew C Smith, Todd B Parrish, Rebecca Abbott, Mark A Hoggarth, Karl Mendoza, Yu Fen Chen, James M Elliott

Muscle and nerve (Wiley) USA, 28 March 2014

Medical Imaging

Key words: MRI, muscle fat infiltrates, muscle imaging, muscle/fat fraction, muscle, fat [more]

Oxygen therapy does not increase production and damage induced by reactive oxygen species in focal cerebral ischemia

Li Suna, Guido Wolfertsb, Roland Veltkamp

Neuroscience Letters (Elsevier) Germany, 28 March 2014

Neuroscience

Key words: Cerebral ischemia, oxygen therapy, HBO, reactive oxygen species, SOD2 [more]

Myofibroblasts in Murine Cutaneous Fibrosis Originate From Adiponectin-Positive Intradermal Progenitors

Roberta Goncalves Marangoni, Benjamin D Korman, Jun Wei, Tammara A Wood, Lauren V Grham, Michael L Whithfield, Philipp E Scherrr, Warren G Tourtellott, John Varga

Arthritis & Rheumatology (Wiley) USA, 27 March 2014

Rheumatology

Key words: Myofibroblasts, systemic sclerosis, growth factor β, canonical adipogenic markers [more]

In vivo real-time fluorescence visualization and brain-targeting mechanisms of lipid nanocarriers with different fatty ester:oil ratios

Chih-Jen Wen, Tzu-Chen Yen, Saleh A Al-Suwayeh, Hui-Wen Chang, Jia-You Fang

Future Medicine (FSG) Taiwan, Saudi Arabia, 27 March 2014

Nanomedicine

Key words: Lipid nanocarriers, cetyl palmitate, squalene, sulforhodamine B [more]

RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis

Marion Lapierre, Sandrine Bonnet, Caroline Bascoul-Mollevi, Imade Ait-Arsa, Stéphan Jalaguier, Maguy Del Rio, Michela Plateroti, Paul Roepman, Marc Ychou, Julie Pannequin, Frédéric Hollande, Malcolm Parker, and Vincent Cavailles1

The Journal of Clinical Investigation (American Society for Clinical Investigation) France, The Netherlands, UK, 25 March 2014

Oncology

[more]

Ambivalent role of pFAK-Y397 in serous ovarian cancer-a study of the OVCAD consortium

Stefanie Aust, Katharina Auer, Anna Bachmayr-Heyda, Carsten Denkert, Jalid Sehouli, Ioana Braicu, Sven Mahner, Sandrina Lambrechts, Ignace Vergote, Christoph Grimm, Reinhard Horvat, Dan Cacsire Castillo-Tong, Robert Zeillinger Dietmar Pils

Molecular Cancer (Springer) Austria, Germany, Belgium, 21 March 2014

Oncology

Key words: FAK, pFAK, molecular subclassification, immunohistochemistry, prognosis, ovarian cancer [more]

Protection against Dengue Virus Infection in Mice by Administration of Antibodies against Modified Nonstructural Protein 1

Shu-Wen Wan, Yi-Tien Lu, Chia-Hui Huang, Chiou-Feng Lin, Robert Anderson, Hsiao-Sheng Liu, Trai-Ming Yeh, Yu-Ting Yen, Betty A Wu-Hsieh , Yee-Shin Lin

PLoS One (PLOS) Taiwan, Canada, 21 March 2014

Virology

Key words: Hemorrhage, endothelial cells, platelets, complement system, dengue fever, hematoxylin staining, inoculation, macrophages [more]

Lamin B2 prevents chromosome instability by ensuring proper mitotic chromosome segregation

T Kuga, H Nie, T Kazami, M Satoh, K Matsushita, F Nomura, K Maeshima, Y Nakayama and T Tomonaga

Oncogenesis (Nature) Japan, 17 March 2014

Oncology

Key words: Chromosome segregation, Colorectal cancer, Mitotic spindle [more]

Hedgehog Pathway Inhibition in Chondrosarcoma Using the Smoothened Inhibitor IPI-926 Directly Inhibits Sarcoma Cell Growth

Veronica T Campbell, Puviindran Nadesan, S Amanda Ali, Chang Ye Yale Wang, Heather Whetstone, Raymond Poon, Qingxia Wei, John Keilty, Jennifer Proctor, Lauren W Wang, Suneel S Apte, Karen McGovern, Benjamin A Alman, Jay S Wunder

Molecular Cancer Therapeutics (AACR Publications) USA, Canada, 14 March 2014

Oncology

Key words: Hedgehog (Hh) pathway, Chondrosarcoma, transmembrane receptor Patched [more]

Blockade of Fas Signaling in Breast Cancer Cells Suppresses Tumor Growth and Metastasis via Disruption of Fas Signaling-initiated Cancer-related Inflammation

Qiuyan Liu, Qinchun Tan, Yuanyuan Zheng, Kun Chen, Cheng Qia, Nan Li, Qingqing Wang, Xuetao Cao

Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) China, 13 March 2014

Oncology

Key words: Breast Cancer, fas inflammation, prostaglandins, tumor metastases IL-6 MDSC PGE2 [more]

Interleukin-1β Attenuates Myofibroblast Formation and Extracellular Matrix Production in Dermal and Lung Fibroblasts Exposed to Transforming Growth Factor-β1

Masum M Mia, Ruud A Bank, Miriam Boersema

PLoS One (PLOS) The Netherlands, 12 March 2014

Cell Biology

Key words: Fibroblasts, collagens, gene expression, fibrosis, immunofluorescence staining, tissue repair, cytokines, lungs [more]

5th International meeting on angiogenesis

Angiogenesis (Springer) The Netherlands, 08 March 2014

Regenerative Medicine

Impact of the Smoothened Inhibitor, IPI-926, on Smoothened Ciliary Localization and Hedgehog Pathway Activity

Marisa O Peluso, Veronica T Campbell, Joseph A Harari, Thomas T Tibbitts, Jennifer L Proctor, Nigel Whitebread, James M Conley, Kerry F White, Jeffery L Kutok, Margaret A Read, Karen McGovern, Kerrie L Faia

PLoS One (PLOS) USA, 07 March 2014

Oncology

Key words: Hedgehog signaling NIH 3T3 cells, cancer treatment, cell binding assay, cilia, gene expression, luciferase, cell staining [more]

Excessive activation of the alternative complement pathway in autosomal dominant polycystic kidney disease

Z Su, X Wang, Gao,YLiu, CPan, H Hu, R P Beyer, M Shi, J Zhou, J Zhang, A L Serra, R P Wüthrich, C Mei

Journal of Internal Medicine (Wiley) China, Switzerland, USA, 02 March 2014

Nephrology

Key words: Autosomal dominant polycystic kidney disease, complement, complement inhibitor, glycoproteomics, urine [more]

AB0206 Altered Expression of Angiopoietins and Tie-2 in Ischemic Lesions of UCD-206 Chickens, an Animal Model for Systemic Sclerosis

S Allipour Birgani, H Dietrich, R Sgonc

Annals of the Rheumatic Diseases (BMJ Journals) Austria, 01 March 2014

Rheumatology

Key words: Systemic sclerosis, vascular endothelial growth factor , endothelial cells

Multimodality imaging to assess immediate response to irreversible electroporation in a rat liver tumor model

Yue Zhang, Sarah B White, Jodi R Nicolai, Zhuoli Zhang, Derek L West, Dong-hyun Kim, A Lee Goodwin, Frank H Miller, Reed A Omary, Andrew C Larson

Radiology (Radiological Society of North America) USA, 18 February 2014

Oncology

[more]

Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma

Winnie W Lo, Jay S Wunder, Brendan C Dickson, Veronica Campbell, Karen McGovern , Benjamin A Alman, Irene L Andrulis

Cancer (Wiley) Canada, USA, 15 February 2014

Oncology

Key words: Osteosarcoma, hedgehog signaling, ligand-dependent, IPI-926, microenvironment [more]

Iron deficiency alters megakaryopoiesis and platelet phenotype independent of thrombopoietin

Rayko Evstatiev, Adam Bukaty, Kristine Jimenez, Stefanie Kulnigg-Dabsch, Lidia Surman, Werner Schmid, Robert Eferl, Kathrin Lippert, Barbara Scheiber-Mojdehkar, Hans Michael Kvasnicka, Vineeta Khare, Christoph Gasch

American Journal of Hematology (Wiley) Austria, Germany, 14 February 2014

Hematology

Key words: Iron deficiency [more]

NKG2D+ IFN-γ+ CD8+ T Cells Are Responsible for Palladium Allergy

Mitsuko Kawano, Masafumi Nakayama, Yusuke Aoshima, Kyohei Nakamura, Mizuho Ono, Tadashi Nishiya, Syou Nakamura, Yuri Takeda, Akira Dobashi, Akiko Takahashi, Misato Endo, Akiyo Ito, Kyosuke Ueda, Naoki Sato, Shigehito Higuchi, Takeru Kondo, Suguru Hashimoto, Masamichi Watanabe, Makoto Watanabe, Tetsu Takahashi,Keiichi Sasaki, Masanori Nakamura, Takehiko Sasazuki, Takayuki Narushima, Ryuji Suzuki, Kouetsu Ogasawara

PLoS One (PLOS) Japan, 12 February 2014

Allergy Research

Key words: T cells, cytotoxic T cells, allergies, mouse models, adoptive transfer, lymphocytes, allergy immunotherapy, lymph nodes [more]

Successful treatment of adult onset Langerhans cell histiocytosis with bi-weekly administration of pegylated interferon-α

Sadanori Furudate, Taku Fujimura, Yumi Kambayashi, Mitsuko Kawano, Kouetsu Ogasawara, Akira Tsukada, Erika Tamabuchi, Takahiro Haga, Akira Hashimoto and Setsuya Aiba

Acta Dermato Venereologica (Ingentaconnect) Japan, 04 February 2014

Dermatology

[more]

Serum Level of IL-10 Is Increased in Patients with Endometriosis, and IL-10 Promotes the Growth of Lesions in a Murine Model

Jau-Ling Suen, Yu Chang, Pu-Rong Chiu, Tsung-Hua Hsieh, Edward Hsi, Yu-Chieh Chen, Yu-Fang Chen, Eing-Mei Tsai

The American Journal of Pathology (American Society for Investigative Pathology) Taiwan, 01 February 2014

Pathology

Key words: Immune dysregulation, anti-inflammatory cytokine IL-10, Monocyte-derived dendritic cells [more]

Metformin anti-tumor effect via disruption of the MID1 translational regulator complex and AR downregulation in prostate cancer cells

Ummuhan Demir, Andrea Koehler, Rainer Schneider, Susann Schweiger, Helmut Klocker

BMC Cancer (Springer) Austria, Germany, 31 January 2014

Oncology

Key words: Metformin, Androgen receptor, MID1-α4/PP2A protein complex, AMPK , Translational regulation, CoIP [more]

Role of oncogenic K-Ras in cancer stem cell activation by aberrant Wnt/β-catenin signaling

BS Moon, WJ Jeong, J Park, TI Kim, DS Min, KY Choi

Journal of the National Cancer Institute (Oxford University Press) South Korea, 31 January 2014

Oncology

Key words: signal transduction, mutation, cd44 antigens, transplantation, heterologous, mice, neoplasms, k-ras oncogene, homing-associated cell adhesion molecule, cancer stem cells [more]

Die prognostische Bedeutung von Tumor-infiltrierenden CD8+Zellen: eine detaillierte Analyse in Hinblick auf Tumor-Debulking und Zell-Proliferation

S Aust, A Bachmayr-Heyda, S Polterauer, D Pils, DC Castillo-Tong, OVCAD Consortium

Geburtshilfe und Frauenheilkunde (Thieme) Austria, 30 January 2014

Immunology

The role of the organic anion transporting polypeptide OATP4A1 in immunactivation in colorectal cancer and inflammatory colon disease.

Christoph Alexander Ausch, Simone Zotter, Maidah Scheikh, Heike Bauer, Marina Mollik, Erika Bajna, Christian Sebesta, Angelika Reiner, Theresia Thalhammer and Veronika Buxhofer-Ausch

Journal of Clinical Oncology (American Society of Clinical Oncology) , 20 January 2014

Oncology

Key words: Prostaglandins, cyclic nucleotides, second messenger proteins, tumor cells growth

A dual role for autophagy in a murine model of lung cancer

Shuan Rao, Luigi Tortola, Thomas Perlot, Gerald Wirnsberger, Maria Novatchkova, Roberto Nitsch, Peter Sykacek, Lukas Frank, Daniel Schramek, Vukoslav Komnenovic, Verena Sigl, Karin Aumayr, Gerald Schmauss, Nicole Fellner, Stephan Handschuh, Martin Glösmann, Pawel Pasierbek, Michaela Schlederer, Guenter P Resch, Yuting Ma, Heng Yang, Helmuth Popper, Lukas Kenner, Guido Kroemer and Josef M Penninger

Nature Communications (Nature) Austria, France, 20 January 2014

Oncology

Key words: Autophagy, Lung cancer, Oncogenesis [more]

Glycogen Synthase Kinase 3β (GSK3β) Regulates Differentiation and Proliferation in Neural Stem Cells from the Rat Subventricular Zone 1

Martin H Maurer, Jens O Brömme, Robert E Feldmann, Jr Anne Järve, Fatemeh Sabouri, Heinrich F Bürgers, Dominik W Schelshorn, Carola Krüger, Armin Schneider, Wolfgang Kuschinsky

Journal of Proteome Research (ACS Publications) Germany, 18 January 2014

Stem Cell Research

Key words: Neural stem cell, Neurosphere, Glycogen Synthase Kinase 3β, Two-dimensional gel electrophoresis, Rat, Subventricular zone [more]

NF-E2-related factor 2 promotes compensatory liver hypertrophy after portal vein branch ligation in mice

Keiichi Shirasaki, Keiko Taguchi, Michiaki Unno, Hozumi Motohashi, Masayuki Yamamoto

Hepatology (Wiley) Japan, 17 January 2014

Hepathology

Key words: Hepatectomy, portal vein embolization, phosphoinositide 3-kinase, protein kinase B (PI3K/Akt) pathway [more]

Hepatic RIG-I Predicts Survival and Interferon-α Therapeutic Response in Hepatocellular Carcinoma

Jin Hou, Ye Zhou, Yuanyuan Zheng, Jia Fan, Weiping Zhou, Irene OL Ng, Huichuan Sun, Lunxiu Qin, Shuangjian Qiu, Joyce MF Lee, Chung-Mau Lo, Kwan Man, Yuan Yang, Yun Yang, Yingyun Yang, Qian Zhang, Xuhui Zhu, Nan Li, Zhengxin Wang, Guoshan Ding, Shi-Mei Zhuang, Limin Zheng, Xiaoling Luo, Yuan Xie, Anmin Liang, Zhugang Wang, Ming Zhang, Qiang Xia, Tingbo Liang, Yizhi Yu, Xuetao Cao

Cancer Cell (Cell Press) China, 13 January 2014

Oncology

Key words: Hepatocellular carcinoma, interferon-α, retinoic acid-inducible gene-I [more]

Diverse T-cell responses characterize the different manifestations of cutaneous graft-versus-host disease

Marie-Charlotte Brüggen, Irene Klein, Hildegard Greinix, Wolfgang Bauer, Zoya Kuzmina, Werner Rabitsch, Peter Kalhs, Peter Petzelbauer, Robert Knobler, Georg Stingl, Georg Stary

Blood (American Society of Hematology) Austria, 09 January 2014

Transplantation Medicine

Key words: Distinct T-cell patterns characterize the acute and chronic forms of cutaneous GVHD, increased TSLP expression is an indicator of acute cutaneous GVHD development. [more]

Macrophage Quantification in Different Breast Tumor Compartments.

Haisan, Anca, Petreus, T, Jitaru, Daniela, Danciu, M, Carasevici, E

Jurnalul de Chirurgie (search.ebscohost.com) Romania, 01 January 2014

Oncology

Resveratrol enhances the chemopreventive effect of celecoxib in chemically induced breast cancer in rats

Terézia Kisková, Rastislav Jendzelovsky, Erdenetsetsek Rentsen, Alexandra Maier-Salamon, Natalia Kokosova, Zuzana Papcova,Jaromır Mikes, Peter Orendas, Bianka Bojkova, Peter Kubatka, Martin Svoboda, Karol Kajo, Peter Fedorocko, Walter Jager, Cem Ekmekcioglu, Monika Kassayova and Theresia Thalhammer

European Journal of Cancer Prevention (Wolters Kluwer) Austria, 01 January 2014

Oncology

Key words: celecoxib, chemically induced breast cancer, COX2, GDF15, MCF-7 cells, oxidative stress, resveratrol [more]

Lymph node status assessed through the log odds ratio–a better tool in the prognosis of colorectal cancer relapse

ST Makkai-Popa, S Luncă, E Târcoveanu, E Carasevici, G Dimofte

Romanian Journal of Morphology and Embryology () Romania, 01 January 2014

Oncology

Key words: disease-free interval, lymph node ratio, log odds ratio.

HISTOQUEST–MODALITY OF MICROANATOMICAL ANALYSIS OF THE IMMUNOHISTOCHEMICAL COLORATION IN BREAST CANCER AND DATA …

Vrânceanu, Anca, Tărniceriu, Claudia Cristina, Makkai, S, Carasevici, E

(search.ebscohost.com) Romania, 01 January 2014

Oncology

Role of endocytic uptake in transfection efficiency of solid lipid nanoparticles-based nonviral vectors

Aritz Perez Ruiz de Garibay, María Ángeles Solinís Aspiazu, Alicia Rodríguez Gascón, Haleh Ganjian, Renate Fuchs

Journal of Gene Medicine (Wiley) Spain, Austria, 27 December 2013

Nanomedicine

Key words: Endocytosis, lysosome, nonviral vector, solid lipid nanoparticles, transfection [more]

Ginsenoside Rg3 Up-regulates the Expression of Vascular Endothelial Growth Factor in Human Dermal Papilla Cells and Mouse Hair Follicles

Dae Hyun Shin, Youn Jeong Cha, Kyeong Eun Yang, Ik-Soon Jang, Chang-Gue Son, Bo Hyeon Kim, Jung Min Kim

Phytotherapy Research (Wiley) South Korea, 26 December 2013

Dermatology

Key words: Rg3, hair growth, DP cell, gene expression profiles, VEGF, stemness marker [more]

Application of quinidine on rat sciatic nerve decreases the amplitude and increases the latency of evoked responses

Kuang-I Cheng, I-Ling Lin, Lin-Li Chang, I-Ming Jou, Chung-Sheng Lai, Jhi-Joung Wang, Hung-Chen Wang, Aij-Lie Kwan

Journal of Anesthesia (Springer) Taiwan, 15 December 2013

Anesthesiology

Key words: Sciatic nerve, lidocaine, sciatic nerve fiber, contralateral hind limb, rat sciatic nerve, quinidine concentration, sodium channel, ranvier node, myelinated nerve fiber, local anesthetic, nerve conduction, peripheral nerve, neuropathic pain, conduction velocity [more]

Autophagy suppresses tumorigenesis of hepatitis B virus-associated hepatocellular carcinoma through degradation of microRNA-224

Sheng-Hui Lan, Shan-Ying Wu, Roberto Zuchini, Xi-Zhang Lin, Ih-Jen Su, Ting-Fen Tsai, Yen-Ju Lin, Cheng-Tao Wu and Hsiao-Sheng Liu

Hepatology (Wiley) Taiwan, 13 December 2013

Oncology

Key words: microRNA-224, miR‐224 antagonist, autophagosome fraction, autophagy‐related genes, chloroquine, double distilled water, digoxigenin, hepatitis B virus, hepatitis B virus X protein, hepatocellular carcinoma, hepatitis C virus [more]

Overexpression of FGF9 in colon cancer cells is mediated by hypoxia-induced translational activation

Tsung-Ming Chen, Yu-Heng Shih, Joseph T Tseng, Ming-Chih Lai, Chih-Hao Wu, Yi-Han Li, Shaw-Jenq Tsai, H Sunny Sun

Nucleic Acids Research (Oxford University Press) Taiwan, 10 December 2013

Oncology

Key words: Human fibroblast growth factor 9 , hypoxia, colon cancer cells [more]

Localized Hyperthermia with Iron Oxide–Doped Yttrium Microparticles: Steps toward Image-Guided Thermoradiotherapy in Liver Cancer

Andrew C Gordon, Robert J Lewandowski, Riad Salem, Delbert E Day, Reed A Omary, Andrew C Larson

Journal of Vascular and Interventional Radiology (Elsevier) USA, 06 December 2013

Oncology

Key words: Hepatocellular carcinoma, normal hepatic parenchyma, alternating magnetic field [more]

MAR-mediated integration of plasmid vectors for in vivo gene transfer and regulation

Stefania Puttini, Ruthger W van Zwieten, Damien Saugy, Malgorzata Lekka, Florence Hogger, Deborah Ley, Andrzej J Kulik, Nicolas Mermod

BMC Molecular Biology (Springer) Switzerland, Poland, 02 December 2013

Genetics

Key words: Inducible expression, non-viral vectors, MAR elements, erythropoietin, utrophin, gene therapy [more]

Langerhans cell maturation is accompanied by induction of N-cadherin and the transcriptional regulators of epithelial–mesenchymal transition ZEB1/2

Sabine Konradi, Nighat Yasmin1, Denise Haslwanter, Michele Weber, Bernhard Gesslbauer, Michael Sixt, Herbert Strobl

European Journal of Immunology (Wiley) Austria, 02 December 2013

Immunology

Key words: Cell migration, dendritic cells, epithelial-to-mesenchymal transition, langerhans cells, maturation [more]

Targeting SOD1 reduces experimental non–small-cell lung cancer

Andrea Glasauer, Laura A Sena, Lauren P Diebold, Andrew P Mazar, and Navdeep S Chandel

The Journal of Clinical Investigation (American Society for Clinical Investigation) USA, 02 December 2013

Oncology

[more]

Transdifferentiation of Adipose-Derived Stem Cells into Keratinocyte-Like Cells: Engineering a Stratified Epidermis

Claudia Chavez-Munoz, Khang T Nguyen,Wei Xu, Seok-Jong Hong,Thomas A Mustoe, Robert D Galiano

PLoS One (PLOS) USA, 02 December 2013

Stem Cell Research

Key words: Keratinocytes, cell staining, transdifferentiation, cell differentiation, mesenchymal stem cells, DAPI staining, antibiotics, fibroblasts [more]

A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog

Astrid Hagelkruys, Sabine Lagger, Julia Krahmer, Alexandra Leopoldi, Matthias Artaker, Oliver Pusch, Jürgen Zezua, Simon Weissmann, Yunli Xie, Christian Schöfer, Michaela Schlederer, Gerald Brosch, Patrick Matthias, Jim Selfridge, Hans Lassmann, Jürgen A Knoblich, Christian Seiser

Development (The Company of Biologists) Austria, Switzerland, UK, 19 November 2013

Neuroscience

Key words: Histone deacetylases, neural cells, histone acetyltransferases, central nervous system [more]

Developmental and oncogenic radiation effects on neural stem cells and their differentiating progeny in mouse cerebellum

Mirella Tanori, Emanuela Pasquali, Simona Leonardi, Arianna Casciati, Paola Giardullo, Ilaria De Stefano, Mariateresa Mancuso, Anna Saran, Simonetta Pazzaglia

Stem Cells (Wiley) Italy, 15 November 2013

Stem Cell Research

Key words: Ptc1+/- mice, apoptosis, DNA repair, p21, medulloblastoma, carcinogenesis, neural stem cells, progenitor cells [more]

Epidermal Growth Factor Receptor Targeted Nuclear Delivery and High-Resolution Whole Cell X-ray Imaging of Fe3O4@TiO2 Nanoparticles in Cancer Cells

Ye Yuan, Si Chen, Tatjana Paunesku, Sophie Charlotte Gleber, William C Liu, Caroline B Doty, Rachel Mak, Junjing Deng, Qiaoling Jin, Barry Lai, Keith Brister, Claus Flachenecker, Chris Jacobsen, Stefan Vogt, Gayle E Woloschak

ACS NANO (ACS Publications) USA, 12 November 2013

Medical Imaging

Key words: Nanoparticles, titanium dioxide, photoactivation, X-ray fluorescence microscopy, epidermal growth factor receptor [more]

Cardiac magnetic resonance postcontrast T1 time is associated with outcome in patients with heart failure and preserved ejection fraction

Mascherbauer J, Marzluf BA, Tufaro C, Pfaffenberger S, Graf A, Wexberg P, Panzenböck A, Jakowitsch J, Bangert C, Laimer D, Schreiber C, Karakus G, Hülsmann M, Pacher R, Lang IM, Maurer G, Bonderman D

Circulation:Cardiovascular Imaging (AHA Journals) Austria, Turkey, 06 November 2013

Cardiology

Key words: Hypertension, pulmonary, magnetic resonance imaging, prognosis [more]

Alcohol Exacerbates LPS-Induced Fibrosis in Subclinical Acute Pancreatitis

Haitao Gu, Franco Fortunato, Frank Bergmann, Markus W Büchler, David C Whitcomb, Jens Werner

The American Journal of Pathology (Elsevier) Germany, 01 November 2013

Gastroenterology

Key words: Pancreatic acinar cells, alcoholic acute pancreatitis, growth factor-β of acinar cells, pancreatic fibrosis [more]

Hypercapnia Impairs Lung Neutrophil Function and Increases Mortality in Murine Pseudomonas Pneumonia

Khalilah L Gates , Heather A Howell , Aisha Nair , Christine U Vohwinkel , Lynn C Welch , Greg J Beitel , Alan R Hauser , Jacob I Sznajder , and Peter H S Sporn

American Journal of Respiratory Cell and Molecular Biology (ATS Journals) USA, 01 November 2013

Pulmonology

Key words: arbon dioxide, pulmonary infection, reactive oxygen species, phagocytosis, inflammation [more]

Corelation of Lymphocytic Infiltrates with the Prognosis of Recurrent Colo-Rectal Cancer

ST Makkai-Popa, S Luncã, G Dimofte, A Vrânceanu, D Franciug, I Ivanov, F Zugun, E Târcoveanu, E Carasevici

Chirurgia (revistachirurgia) Romania, 01 November 2013

Oncology

Key words: relapse prognosis, colo-rectal cancer, quantitative assessment of immunohistochemical staining, digital image analysis, cytotoxic T cells [more]

Targeting of sodium–glucose cotransporters with phlorizin inhibits polycystic kidney disease progression in Han: SPRD rats

X Wang, S Zhang, Y Liu, D Spichtig, S Kapoor, H koepsell, N Mohebbi, S Sergerer, AL Serra, D Rodriguez, O Devuyst, C Mei, RP Wüthrich

Kidney international (Elsevier) Switzerland, China, Germany, 01 November 2013

Nephrology

Key words: polycystic, phlorizin, rat, sodium–glucose cotransport [more]

Renal Heparan Sulfate Proteoglycans Modulate Fibroblast Growth Factor 2 Signaling in Experimental Chronic Transplant Dysfunction

Kirankumar Katta, Miriam Boersema, Saritha Adepu, Heleen Rienstra, Johanna WAM Celie, Rik Mencke, Grietje Molema, Harry van Goor, Jo HM Berden, Gerjan Navis, Jan-Luuk Hillebrands, Jacob van den Born

The American Journal of Pathology (Elsevier) The Netherlands, 01 November 2013

Transplantation Medicine

Key words: Renal transplantation, proteoglycans, chronic transplant dysfunction, laser-microdissected glomeruli [more]

AKIP1, a cardiac hypertrophy induced protein that stimulates cardiomyocyte growth via the Akt pathway

H Yu, W Tigchelaar, B Lu, WH van Gilst, RA De Boer, B Daan Westenbrink, HHW Sillje

International Journal of Molecular Sciences (MDPI) The Netherlands, China, 28 October 2013

Cardiology

Key words: cardiac hypertrophy, AKIP1, Akt, kinase, remodeling [more]

Regulation of the calcium-sensing receptor expression by 1,25-dihydroxyvitamin D3, interleukin-6, and tumor necrosis factor alpha in colon cancer cells

Irfete S Fetahu, Doris M Hummel, Teresa Manhardt, Abhishek Aggarwal, Sabina Baumgartner-Parzer, Eniko Kállay

The Journal of Steroid Biochemistry and Molecular Biology (Elsevier) Austria, 28 October 2013

Oncology

Key words: Calcium-sensing receptor, colon cancer, tumor necrosis factor alpha, interleukin, 1, 25-dihydroxyvitamin D3, Inflammation [more]

Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie

Oncology research and treatment (Karger) Austria, 22 October 2013

Oncology

Effects on tumor development and metastatic dissemination by the NKG2D lymphocyte receptor expressed on cancer cells

A El-Gazzar, X Cai, R S Reeves, Z Dai, A Caballero-Benitez, D L McDonald, J Vazquez, T A Gooley, G E Sale, T Spies and V Groh

Oncogene (Nature) USA, 21 October 2013

Oncology

Key words: Breast cancer, Metastasis, Oncogene proteins, Oncogenesis [more]

Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation

Marco Peviani, Eleonora Salvaneschi, Leonardo Bontempi, Alessandro Petese, Antonio Manzo, Daniela Rossi, Mario Salmona, Simona Collina, Paolo Bigini, Daniela Curti

Neurobiology of Disease (Elsevier) Italy, 16 October 2013

Neuroscience

Key words: Sigma-1 receptor, motor neurons, BDNF, reactive gliosis, neurodegeneration, obbler [more]

Overexpression of the Transcriptional Repressor Complex BCL-6/BCoR Leads to Nuclear Aggregates Distinct from Classical Aggresomes

Elisabeth Buchberger, Miriam El Harchi, Dietmar Payrhuber, Anna Zommer, Dominic Schauer, Ingrid Simonitsch-Klupp, Martin Bilban, Christine Brostjan

PLoS One (PLOS) Austria, 11 October 2013

Cell Biology

Key words: Transfection, chaperone proteins, heat shock response, plasmid construction, cell staining, immunostaining, nuclear bodies, protein structure [more]

Suberoylanilide Hydroxamic Acid, an Inhibitor of Histone Deacetylase, Enhances Radiosensitivity and Suppresses Lung Metastasis in Breast Cancer In Vitro and In Vivo

Hui-Wen Chiu, Ya-Ling Yeh, Yi-Ching Wang, Wei-Jan Huang, Yi-An Chen, Yi-Shiou Chiou, Sheng-Yow Ho, Pinpin Lin, Ying-Jan Wang

PLoS One (PLOS) Taiwan, 10 October 2013

Oncology

Key words: Cancer treatment, autophagic cell death, breast cancer, DNA damage, apoptosis, metastasis, fluorescence microscopy, DNA repair [more]

Necro-inflammatory response of pancreatic acinar cells in the pathogenesis of acute alcoholic pancreatitis

H Gu, J Werner, F Bergmann, DC Whitcomb, MW Büchler, F Fortunato

Cell Death & Disease (Nature) Germany, USA, 03 October 2013

Gastroenterology

Key words: Acute pancreatitis, Inflammation, Necroptosis [more]

Characterization of T Cell Receptors of Th1 Cells Infiltrating Inflamed Skin of a Novel Murine Model of Palladium-Induced Metal Allergy

Hiroshi Kobayashi, Kenichi Kumagai, Takanori Eguchi, Hiroaki Shigematsu, Kazutaka Kitaura, Mitsuko Kawano, Tatsuya Horikawa, Satsuki Suzuki, Takaji Matsutani, Kouetsu Ogasawara, Yoshiki Hamada, Ryuji Suzuki

PLoS One (PLOS) Japan, 03 October 2013

Allergy Research

Key words: T cells, allergies, T cell receptors, polymerase chain reaction, cytokines, inflammation, chemokines, sequence analysis [more]

Comparison of Interleukin-17- Producing Cells in Different Clinical Types of Alopecia Areata

Tojo G, Fujimura T, Kawano M, Ogasawara K, Kambayashi Y,Furudate S, Mizuashi M, Aiba S

Dermatology (Karger) Japan, 01 October 2013

Dermatology

Key words: Alopecia areata Interleukin-17 Interferon Acute, diffuse and total alopecia [more]

Expression Of CD8 Is Associated With Non-Common Type Morphology And Outcome In Pediatric Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma

Dmitriy Abramov, Ilske Oschlies, Martin Zimmermann, Dmitriy Konovalov, Christine Damm-Welk, Wilhelm Wössmann, Wolfram Klapper

Haematologica (Ferrata Storti Foundation) Germany, Russia, 01 October 2013

Oncology

Key words: Anaplastic lymphoma kinase, CD30-positive T-cell lymphoma, vinblastine, autologous, allogeneic hematopoietic stem cell transplantation [more]

Up-Regulation of SOX9 in Sertoli Cells from Testiculopathic Patients Accounts for Increasing Anti-Mullerian Hormone Expression via Impaired Androgen Receptor Signaling

Kuo-Chung Lan, Yen-Ta Chen, Chawnshang Chang, Yung-Chiao Chang, Hsin-Jung Lin, Ko-En Huang, Hong-Yo Kang

PLoS One (PLOS) Taiwan, USA, 01 October 2013

Endocrinology

Key words: Sertoli cells, testes, androgens, spermatogenesis, reverse transcriptase-polymerase chain reaction, testosterone, adults, germ cells [more]

Digital immunohistochemistry: new horizons and practical solutions in breast cancer pathology

Arvydas Laurinavicius, Justinas Besusparis, Justina Didziapetryte, Gedmante Radziuviene, Raimundas Meskauskas Aida Laurinaviciene

Diagnostic Pathology (BioMed Central) Lithuania, 30 September 2013

Oncology

Key words: Breast cancer, Immunohistochemistry (IHC) biomarkers, tissue microarray [more]

Loss of phosphatase and tensin homolog (PTEN) in myeloid cells controls inflammatory bone destruction by regulating the osteoclastogenic potential of myeloid cells

Stephan Blüml, Martin Friedrich, Tobias Lohmeyer, Emine Sahin, Victoria Saferding, Julia Brunner, Antonia Puchner, Peter Mandl, Birgit Niederreiter, Josef S Smolen, Gernot Schabbauer, Kurt Redlich

Annals of the Rheumatic Diseases (BMJ Journals) Austria, 27 September 2013

Rheumatology

Key words: Rheumatic diseases, osteoclasts, Phosphoinositide-3-Kinase, Phosphatase and tensin homolog [more]

Direct Comparison of Autologous and Allogeneic Transplantation of iPSC-Derived Neural Cells in the Brain of a Nonhuman Primate

Morizane A, Doi D, Kikuchi T, Okita K, Hotta A, Kawasaki T, Hayashi T, Onoe H, Shiina T, Yamanaka S, Takahashi J

Stem Cell Reports (Cell Press) Japan, 26 September 2013

Transplantation Medicine

[more]

Prognostic impact of tumor infiltrating CD8+ T cells in association with cell proliferation in ovarian cancer patients - a study of the OVCAD consortium

Anna Bachmayr-Heyda, Stefanie Aust, Georg Heinze, Stephan Polterauer, Christoph Grimm, Elena Ioana Braicu, Jalid Sehouli, Sandrina Lambrechts, Ignace Vergote, Sven Mahner, Dietmar Pils, Eva Schuster, Theresia Thalhammer, Reinhard Horvat, Carsten Denkert, Robert Zeillinger, Dan Cacsire Castillo-Tong

BMC Cancer (BioMed Central) Austria, Germany, Belgium, 17 September 2013

Oncology

Key words: Epithelial ovarian cancer, Cytotoxic T cells, Tumor proliferation, Prognostic impact, Residual tumor [more]

A single extra copy of Dscr1 improves survival of mice developing spontaneous lung tumors through suppression of tumor angiogenesis

Jimin Shin, Jang Choon Lee, Kwan-Hyuck Baek

Cancer Letters (Elsevier) South Korea, 16 September 2013

Oncology

Key words: Down syndrome, cancer, angiogenesis, Dscr1, Spontaneous lung tumorigenesis [more]

Contribution of Toll-Like Receptor 2 to the Innate Response against Staphylococcus aureus Infection in Mice

Yimin, Masashi Kohanawa, Songji Zhao, Michitaka Ozaki,Sanae Haga, Guangxian Nan, Yuji Kuge, Nagara Tamaki

PLoS One (PLOS) Japan, China, 13 September 2013

Immunology

Key words: Staphylococcus aureus, macrophages, cytokines, bacterial pathogens, toll-like receptors, neutrophils, gene expression, blood [more]

Comprehensive characterizations of nanoparticle biodistribution following systemic injection in mice

WY Liao, HJ Li, MY Chang, ACL Tang, AS Hoffman, PCH Hsieh

Nanoscale (Royal Society of Chemistry) Taiwan, USA, 06 September 2013

Nanomedicine

[more]

Digital microscopy assessment of angiogenesis in different breast cancer compartments

Haisan A, Rogojanu R, Croitoru C, Jitaru D, Tarniceriu C, Danciu M, Carasevici E

BioMed Research International (Hindawi Publishing Corporation) Romania, Austria, 01 September 2013

Medical Image Analysis

Key words: Tumour angiogenesis, microvessel density, breast cancer, tumour associated stroma, tumour parenchyma, tumour invasive front. [more]

In vitro and in vivo uptake study of Escherichia coli Nissle 1917 bacterial ghosts: cell-based delivery system to target ocular surface diseases

Elisabeth Stein, Aleksandra Inic-Kanada, Sandra Belij, Jacqueline Montanaro, Nora Bintner, Simone Schlacher, Ulrike Beate Mayr, Werner Lubitz, Marijana Stojanovic, Hristo Najdenski, Talin Barisani-Asenbauer

Investigative Ophthalmology & Visual Science (ARVO Journals) Austria, Serbia, Bulgaria, 01 September 2013

Microbiology

[more]

Expression of E-cadherin, Twist, and p53 and their prognostic value in patients with oral squamous cell carcinoma

Chi-Chen Fan, Tao-Yeuan Wang, Yen-An Cheng, Shih Sheng Jiang, Chien-Wen Cheng, Alan Yueh-Luen Lee, Ting-Yu Kao

Journal of Cancer Research and Clinical Oncology (Springer) Taiwan, 30 August 2013

Oncology

Key words: Ttwist expression, betel quid, betel quid chewing, oscc tissue, reduced e-cadherin, oscc tumor, oral cancer, oral squamous cell carcinoma, oral carcinogenesis, neck cancer, oral epithelium, emt marker, bladder cancer, e-cadherin promoter, emt transcription [more]

Involvement of the Serine Protease Inhibitor, SERPINE2, and the Urokinase Plasminogen Activator in Cumulus Expansion and Oocyte Maturation

Chung-Hao Lu, Robert Kuo-Kuang Lee, Yuh-Ming Hwu, Ming-Huei Lin, Ling-Yu Yeh, Ying-Jie Chen, Shau-Ping Lin, Sheng-Hsiang Li

PLoS One (PLOS) Taiwan, 30 August 2013

Reproductive Medicine

Key words: Oocytes, small interfering RNAs, extracellular matrix, immune serum, ovaries, vector cloning, complementary DNA, gene expression [more]

Glycogen synthase kinase-3β–mediated CCAAT/enhancer-binding protein delta phosphorylation in astrocytes promot es migration and activation of microglia/macrophages

Chiung-Yuan Ko, Wen-Ling Wang, Shao-Ming Wang, Yu-Yi Chu, Wen-Chang Chang, Ju-Ming Wang

Neurobiology of aging (Elsevier) Taiwan, Japan, 29 August 2013

Neuroscience

Key words: Alzheimer's disease, CEBPD, GSK3ß, astrocytes, microglia [more]

Human Cytomegalovirus UL76 Elicits Novel Aggresome Formation via Interaction with S5a of the Ubiquitin Proteasome System

Shin-Rung Lin, Meei Jyh Jiang, Hung-Hsueh Wang, Cheng-Hui Hu, Ming-Shan Hsu, Edward Hsi, Chang-Yih Duh, Shang-Kwei Wang

Journal of Virology (American Society for Microbiology) China, 21 August 2013

Virology

Key words: Cytomegalovirus [more]

Neohesperidin attenuates cerebral ischemia–reperfusion injury via inhibiting the apoptotic pathway and activating the Akt/Nrf2/HO-1 pathway

Journal of Asian Natural Products Research (Taylor and Francis) China, 16 August 2013

Neuroscience

Key words: Cerebral ischemia

Panton-Valentine Leukocidin Facilitates the Escape of Staphylococcus aureus From Human Keratinocyte Endosomes and Induces Apoptosis

Chia-Yu Chi, Chia-Chun Lin, I-Chuang Liao, Yi-Chuan Yao, Fan-Ching Shen, Ching-Chuan Liu, Chiou-Feng Lin

The Journal of Infectious Diseases (Oxford University Press) Taiwan, 15 August 2013

Microbiology

Key words: Endosome keratinocyte, Panton-Valentine leukocidin, Staphylococcus aureus [more]

Circulating alpha-klotho levels are not disturbed in patients with type 2 diabetes with and without macrovascular disease in the absence of nephropathy

Joris van Ark, Hans-Peter Hammes, Marcory C R F van Dijk, Marc G Vervloet, Bruce H R Wolffenbuttel, Harry van Goor, Jan-Luuk Hillebrands

Cardiovascular Diabetology (Springer) The Netherlands, Germany, 14 August 2013

Dermatology

Key words: Vascular, diabetes [more]

Carboxyl-Terminal Modulator Protein Positively Regulates Akt Phosphorylation and Acts as an Oncogenic Driver in Breast Cancer

Yu-Peng Liu, Wen-Chi Liao, Luo-Ping Ger, Jiun-Chin Chen, Tai-I Hsu, Yu-Cheng Lee, Hong-Tai Chang, Yu-Chia Chen, Yi-Hua Jan, Kuen-Haur Lee, Yu-Hao Zeng, Michael Hsiao, Pei-Jung Lu

Cancer Research (AACR Publications) Taiwan, 13 August 2013

Oncology

Key words: Tumorigenesis, cancer cells, carboxy-terminal modulator protein, Akt serine/threonine kinase [more]

A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis

Karoline Kollmann, Gerwin Heller, Christine Schneckenleithner, Wolfgang Warsch, Ruth Scheicher, Rene G Ott, Markus Schäfer, Sabine Fajmann, Michaela Schlederer, Ana-Iris Schiefer, Ursula Reichart, Matthias Mayerhofer, Christoph Hoeller, Sabine Zöchbauer-Müller, Dontscho Kerjaschki, Christoph Bock, Lukas Kenner, Gerald Hoefler, Michael Freissmuth, Anthony R Green, Richard Moriggl, Meinrad Busslinger, Marcos Malumbres, Veronika Sexl

Cancer Cell (Cell Press) Austria, UK, Spain, 12 August 2013

Oncology

Key words: Cell cycle kinase CDK6, pro-angiogenic factor VEGF-A, tumor suppressor p16INK4a [more]

Quantitative magnetization transfer MRI of desmoplasia in pancreatic ductal adenocarcinoma xenografts

Weiguo Li, Zhuoli Zhang, Jodi Nicolai, Guang-Yu Yang, Reed A Omary, Andrew C Larson

NMR in Biomedicine (Wiley) USA, 12 August 2013

Oncology

Key words: Quantitative magnetization transfer, bound proton fraction, desmoplasia, pancreatic cancer, xenograft [more]

Entry of human rhinovirus 89 via ICAM-1 into HeLa epithelial cells is inhibited by actin skeleton disruption and by bafilomycin

Beatrix Pfanzagl, Daniel Andergassen, Johanna Edlmayr, Katarzyna Niespodziana, Rudolf Valenta, Dieter Blaas

Archives of Virology (Springer) Austria, 04 August 2013

Virology

Key words: Hela cell, transferrin, rhabdomyosarcoma, confocal immunofluorescence microscopy, cholesterol depletion, dextran, skeletal muscle cell, stress fiber formation, actin aggregate, lipid raft, breast cancer cell line, infected hela cell, actin patch, rock inhibitor, capsid protein [more]

An interleukin-17–mediated paracrine network promotes tumor resistance to anti-angiogenic therapy

Alicia S Chung, Xiumin Wu, Guanglei Zhuang, Hai Ngu, Ian Kasman, Jianhuan Zhang, Jean-Michel Vernes, Zhaoshi Jiang, Y Gloria Meng, Franklin V Peale, Wenjun Ouyang and Napoleone Ferrara

Nature Medicine (Nature) USA, 04 August 2013

Oncology

Key words: Cancer [more]

Interleukin-1β induced by Helicobacter pylori infection enhances mouse gastric carcinogenesis

Yasuyuki Shigematsu, Tohru Niwa, Emil Rehnberg, Takeshi Toyoda, Satoshi Yoshida, Akiko Mori, Mika Wakabayashi, Yoichiro Iwakura, Masao Ichinose, Yong-Joon Kim, Toshikazu Ushijima

Cancer Letters (Elsevier) Japan, South Korea, 03 August 2013

Oncology

Key words: Interleukin-1ß, gastric cancer, helicobacter pylori infection, inflammation [more]

Impact of constant storage temperatures and multiple warming cycles on the quality of stored red blood cells

T Wagner, M-A Pabst, G Leitinger, U Reiter, N Kozma, G Lanzer, B Huppertz

VoxSanguinis (Wiley) Austria, 02 August 2013

Hematology

Key words: Electron microscopy, quality, RBC, storage, temperature. [more]

Decreased hippocampal MR/GR ratio is associated with low-birth weight in Cynomolgus macaque neonates

JP Buschdorf, SX Ong, K Chng, MJ Meany

Journal of Molecular Endocrinology (Society for Endocrinology) Singapore, 01 August 2013

Reproductive Medicine

Key words: MR:GR ratio, cynomolgus macaque, glucocorticoid receptor, low birth weight [more]

Mobilizing monocytes to cross-present circulating viral antigen in chronic infection

Adam J Gehring, Muzlifah Haniffa, Patrick T Kennedy, Zi Zong Ho, Carolina Boni, Amanda Shin, Nasirah Banu, Adeline Chia, Seng Gee Lim, Carlo Ferrari, Florent Ginhoux, Antonio Bertolett

The Journal of Clinical Investigation (American Society for Clinical Investigation) Singapore, UK, Italy, 01 August 2013

Immunology

[more]

Infliximab induces downregulation of the IL-12/IL-23 axis in 6-sulfo-LacNac (slan)+ dendritic cells and macrophages

Patrick M Brunner, Frieder Koszik, Bärbel Reininger, Madeleine L Kalb, Wolfgang Bauer, Georg Stingl

Journal of Allergy and Clinical Immunology (Elsevier) Austria, 25 July 2013

Allergy Research

Key words: Psoriasis, myeloid dendritic cells, 6-sulfo-LacNac, IL-12p40, TNF-a [more]

Association of gamma-glutamyltransferase with severity of disease at diagnosis and prognosis of ovarian cancer

C Grimm, G Hofstetter, S Aust, I Mutz-Dehbalaie, M Bruch, G Heinze, J Rahhal-Schupp, A Reinthaller, N Concin, S Polterauer

British Journal of Cancer (Nature) Austria, USA, 16 July 2013

Oncology

Key words: Ovarian cancer, Prognostic markers [more]

High resolution MRI for non-invasive mouse lymph node mapping

Zhuoli Zhang , Daniel Procissi, Weiguo Li, Dong-Hyun Kim, Kangan Li, Guohong Han, Yi Huan, Andrew C Larson

Journal of Immunological Methods (Elsevier) USA, China, 11 July 2013

Immunology

Key words: Mouse, Lymph node, Lymphatic drainage, India ink, Magnetic resonance imaging [more]

A phase I trial of aminolevulinic acid-photodynamic therapy for treatment of oral leukoplakia

Stuart J Wong, Bruce Campbell, Becky Massey, Denis P Lynch, Ezra EW Cohen, Elizabeth Blair, Rebecca Selle, Julia Shklovskaya, Borko D Jovanovic, Silvia Skripkauskas, Alexander Dew, Peter Kulesza, Vamsi Parimi, Raymond C Bergan, e, Eva Szabo

Oral Oncology (Elsevier) USA, 08 July 2013

Oncology

Key words: Leukoplakia, aminolevulinic acid, photodynamic therapy, phase I, laser [more]

Vascular Injury Involves the Overoxidation of Peroxiredoxin Type II and Is Recovered by the Peroxiredoxin Activity Mimetic That Induces Reendothelialization

Dong Hoon Kang, Doo Jae Lee, Jiran Kim, Joo Young Lee, Hyun-Woo Kim, Kihwan Kwon, W Robert Taylor, Hanjoong Jo, Sang Won Kang

Circulation (AHA Journals) USA, South Korea, 02 July 2013

Cardiology

Key words: Coronary restenosis, endothelium, peroxiredoxins, reactive oxygen species, receptor protein-tyrosine kinases [more]

Overexpression of Lon contributes to survival and aggressive phenotype of cancer cells through mitochondrial complex I-mediated generation of reactive oxygen species

CW Cheng, CY Kuo, CC Fan, WC Fang, SS Jiang, YK Lo, TY Wang, MC Kao, AYL Lee

Cell Death & Disease (Nature) Taiwan, 20 June 2013

Oncology

Key words: Apoptosis, Cancer metabolism, Pathogenesis [more]

THU0094 Treatment with BGP-15, a Novel Insulin Sensitizer Attenuates Collagen-Induced Arthritis in DBA/1 Mice

P Mandl, S Hayer, S Blüml, V Saferding, D Sykoutri, C Antus, A Szabo, J Smolen, K Redlich

Annals of the Rheumatic Diseases (BMJ Journals) Austria, Hungary, 15 June 2013

Rheumatology

Key words: Arthritis

HPV16 activates the AIM2 inflammasome in keratinocytes

M Reinholz, Y Kawakami, S Salzer, A Kreuter, Y Dombrowski, S Koglin, S Kresse, T Ruzicka, J Schauber

Archives of Dermatological Research (Springer) Germany, 14 June 2013

Dermatology

Key words: Hpv16 dna, aim2 inflammasome, cytosolic dna sensor, inflammasome activation, anal intraepithelial neoplasium, hpv dna, hpv infection, il-1 release, amphotericin, caspase-1 activation, cutaneous wart, il-1 secretion, gentamicin, viral dna, hpv16 18 [more]

Glia, Poster. Cell proliferation, lineages and differentation

C Fenger, M Thomassen, B Emery, T Kuhlmann, TA Kruse, B Finsen

GLIA (Wiley) Denmark, Austria, Australia, 14 June 2013

Neuroscience

Key words: Cell proliferation, lineages, differentiation

A practical approach to immunotherapy of hepatocellular carcinoma using T cells redirected against hepatitis B virus

S Koh, N Shimasaki, R Suwanarusk, ZZ Ho, A Chia, N Banu, S Wu Howland, AS Meoy Ong, AJ Gehring, H Stauss, L Renia, M Sällberg, D Campana, A Bertoletti

Molecular Therapy-Nucleic Acids (Cell Press) Singapore, Sweden, USA, UK, 12 June 2013

Immunology, Virology

Key words: hepatitis B virus, hepatocellular carcinoma, mRNA electroporation, TCR gene therapy [more]

In vivo bioluminescence reporter gene imaging for the activation of neuronal differentiation induced by the neuronal activator neurogenin 1 (Ngn1) in neuronal precursor cells

Hyun Jeong Oh, Do Won Hwang, Hyewon Youn, Dong Soo Lee

European Journal of Nuclear Medicine and Molecular Imaging (Springer) South Korea, 11 June 2013

Neuroscience

Key words: Reporter gene imaging, vector complex, neuronal differentiation, neuronal marker map2, gaussia luciferase, stem cell therapy, human nsc, pluripotent stem cell, grafted stem cell, neural precursor cell, hela cell, neurite outgrowth, nucleic acid delivery, nude mouse, luciferase signal [more]

SYK Inhibition Modulates Distinct PI3K/AKT- Dependent Survival Pathways and Cholesterol Biosynthesis in Diffuse Large B Cell Lymphomas

Linfeng Chen, Stefano Monti ,Przemyslaw Juszczynski, Jing Ouyang, Bjoern Chapuy, Donna Neuberg, John G Doench, Agata M Bogusz,Thomas M Habermann, Ahmet Dogan, Thomas E Witzig, Jeffery L Kutok, Scott J Rodig, Todd Golub, Margaret A Shipp

Cancer Cell (Cell Press) USA, 10 June 2013

Oncology

Key words: B cell receptor, diffuse large B cell lymphoma [more]

Histone acetyl transferase 1 is essential for mammalian development, genome stability, and the processing of newly synthesized histones H3 and H4

Prabakaran Nagarajan, Zhongqi Ge, Bianca Sirbu, Cheryl Doughty, Paula A Agudelo Garcia, Michaela Schlederer, Anthony T Annunziato, David Cortez, Lukas Kenner, Mark R Parthun

PLoS Genetics (PLOS) USA, Austria, 06 June 2013

Genetics

Key words: Histones , Acetylation , Chromatin , Lysine , DNA damage , Mouse models , DNA replication , Neonates [more]

Clinical significance and evolution of hepatic HBsAg expression in HBeAg-positive patients receiving interferon therapy

Tung-Hung Su, Chun-Jen Liu, Hung-Chih Yang, Yung-Ming Jeng, Huei-Ru Cheng, Chen-Hua Liu, Tai-Chung Tseng, Thai-Yen Ling, Pei-Jer Chen, Ding-Shinn Chen, Jia-Horng Kao

Journal of Gastroenterology (Springer) Taiwan, 05 June 2013

Gastroenterology

Key words: Hbsag decline, hbsag expression, on-treatment hbsag, hbsag titer, hbsag clearance, serum hbsag, hbeag loss, hbeag-negative chb, hbv genotype, hbv dna, serum hbv-dna, hbeag-positive chb, hbsag quantification, architect hbsag, viral load [more]

Quantitative Evaluation of Stem Cell Grafting in the Central Nervous System of Mice by In Vivo Bioluminescence Imaging and Postmortem Multicolor Histological Analysis

Kristien Reekmans, Nathalie De Vocht, Jelle Praet, Debbie Le Blon, Chloé Hoornaert, Jasmijn Daans, Annemie Van der Linden, Zwi Berneman, Peter Ponsaerts

Imaging and Tracking Stem Cells (Springer) Belgium, 04 June 2013

Stem Cell Research

Key words: Neural stem cells, mesenchymal stromal cells eGFP, luciferase, cell transplantation, brain, bioluminescence imaging, histology, microglia, astrocytes

Enhanced inhibition of prostate tumor growth by dual targeting the androgen receptor and the regulatory subunit type iα of protein kinase a in vivo

Iris E Eder, Martina Egger , Hannes Neuwirt , Christof Seifarth , Danilo Maddalo , Andreas Desiniotis, Georg Schäfer, Martin Puhr, Jasmin Bektic, Andrew C B Cato and Helmut Klocker

International Journal of Molecular Sciences (MDPI) Austria, Germany, 04 June 2013

Oncology

Key words: androgen receptor, cAMP-dependent protein kinase A, regulatory subunit type Iα, prostate cancer, antisense molecules, dual targeting, LNCaP xenografts, castration resistance [more]

Smooth muscle cell transplantation improves bladder contractile function in streptozocin-induced diabetic rats

Chaitanya Gopinath, Peter Ponsaerts, Erik Fransen, Nele Boeykens, Patrick Pauwels, Jean-Jacques Wyndaele

Cytotherapy (Elsevier) Belgium, 01 June 2013

Transplantation Medicine

Key words: Bladder smooth muscle cells, cell graft survival, cell transplantation, contractile function, diabetes, in vivo cystometry [more]

Biocompatible fluorescent nanoparticles for in vivo stem cell tracking

Lidia Cova, Paolo Bigini, Valentina Diana, Leopoldo Sitia, Raffaele Ferrari, Ruggiero Maria Pesce, Rushd Khalaf, Patrizia Bossolasco, Paolo Ubezio, Monica Lupi, Massimo Tortarolo, Laura Colombo, Daniela Giardino, Vincenzo Silani, Massimo Morbidelli, Mario Salmona and Davide Moscatelli

Nanotechnology (IOP Science) Italy, Switzerland, 20 May 2013

Nanomedicine

Key words: fluorescent nanoparticles, in vivo stem cell tracking, hAFCs, methyl methacrylate (MMA) [more]

Increased Cdc7 expression is a marker of oral squamous cell carcinoma and overexpression of Cdc7 contributes to the resistance to DNA-damaging agents

An Ning Cheng, Shih Sheng Jiang,Chi-Chen Fan, Yu-Kang Lo, Chan-Yen Kuo, Chung-Hsing Chen, Ying-Lan Liu, Chun-Chung Lee, Wei-Shone Chen, Tze-Sing Huang, Tao-Yeuan Wang, Alan Yueh-Luen Lee

Cancer Letters (Elsevier) Taiwan, 16 May 2013

Oncology

Key words: Cdc7, oral cancer, prognostic marker, chemotherapy resistance [more]

Identification and Characterization of Poorly Differentiated Invasive Carcinomas in a Mouse Model of Pancreatic Neuroendocrine Tumorigenesis

Karen E Hunter, Marsha L Quick, Anguraj Sadanandam,Douglas Hanahan, Johanna A Joyce

PLoS One (PLOS) USA, Switzerland, 14 May 2013

Oncology

Key words: Insulin, differentiated tumors, invasive tumors, cell staining, insulinoma, immunofluorescence staining, carcinomas, cell differentiation [more]

Determination of tumor-infiltrating CD8+ lymphocytes in human ovarian cancer

Aust S, Bachmayr-Heyda A, Pils D, Zhao L, Tong W, Berger A, Fogel M, Thalhammer T, Sehouli J, Horvat R, Zeillinger R, Castillo-Tong DC

International Journal of gynecological pathology (Wolters Kluwer) Austria, 10 May 2013

Oncology

Key words: Tumor-infiltrating immune cells, ovarian cancer, CD8+ lymphocytes [more]

Gaseous Hydrogen Sulfide Protects against Myocardial Ischemia-Reperfusion Injury in Mice Partially Independent from Hypometabolism

Pauline M Snijdr , Rudolf A de Boer, Eelke M Bos, Joost C van den Born, Willem-Peter T Ruifrok, Inge Vreeswijk-Baudoin, Marcory C R F van Dijk, Jan-Luuk Hillebrands,Henri G D Leuvenink, Harry van Goor

PLoS One (PLOS) The Netherlands, 10 May 2013

Cardiology

Key words: Reperfusion, necrosis, blood pressure, fibrosis, heart rate, granulocytes, heart , oxygen [more]

Heparanase promotes lymphangiogenesis and tumor invasion in pancreatic neuroendocrine tumors

KE Hunter, C Palermo, JC Kester, K Simpson, JP Li, LH Tang, DS Klimstra, I Vlodavsky and JA Joyce

Oncogene (Nature) USA, Sweden, Israel, 06 May 2013

Oncology

Key words: Lymphangiogenesis, Oncogenesis, Pancreatic cancer [more]

Selected Abstracts from the World Conference on Interventional Oncology (WCIO) 2013

Journal of Vascular and Interventional Radiology (Elsevier) , 01 May 2013

Oncology

Sex differences in IRF5 levels and implications for pDC IFN{alpha} response (P1365)

Morgane Griesbeck, Phillip Tomezsko, Erin Doyle, Michael Sirignano,Thomas Diefenbach, Marcus Altfeld, Judy Chang

The Journal of Immunology (American Association of Immunologists) USA, 01 May 2013

Immunology

Key words: IRF5, Sex differences, pDC IFNα, HIV-1 [more]

Nuclear Localization of CD26 Induced by a Humanized Monoclonal Antibody Inhibits Tumor Cell Growth by Modulating of POLR2A Transcription

Kohji Yamada, Mutsumi Hayashi, Hiroko Madokoro, Hiroko Nishida, Wenlin Du, Kei Ohnuma, Michiie Sakamoto, Chikao Morimoto, Taketo Yamada

PLoS One (PLOS) Japan, 29 April 2013

Oncology

Key words: Cancer treatment, mesothelioma, endocytosis, nuclear membrane, small interfering RNAs, immunoprecipitation, immunoblot analysis, cell membranes [more]

Intra-voxel incoherent motion MRI in rodent model of diethylnitrosamine-induced liver fibrosis

Yue Zhang, Ning Jin, Jie Deng, Yang Guo, Sarah B White, Guang-Yu Yang, Reed A Omary, Andrew C Larson

Magnetic Resonance Imaging (Elsevier) USA, 15 April 2013

Medical Imaging

Key words: Intra-Voxel Incoherent Motion, Diffusion weighted MRI, Liver fibrosis [more]

Fluorescence endoscopy of cathepsin activity discriminates dysplasia from colitis

E Gounaris, J Martin, Y Ishihara, MW Khan, G lee, P Sinh, EZ Chen, M Angarone, R Weissleder, K Khazaie, TA Barrett

Inflammatory bowel Disease (Oxford University Press) USA, 15 April 2013

Gastroenterology

Key words: dysplasia, colitis, macrophages, cathepsin activity, fluorescence endoscopy [more]

Non-Cell-Autonomous Tumor Suppression by p53

Amaia Lujambio, Leila Akkari, Janelle Simon, Danielle Grace, Darjus F Tschaharganeh, Jessica E Bolden, Zhen Zhao, Vishal Thapar, Johanna A Joyce, Valery Krizhanovsky, Scott W Lowe

CELL (Cell Press) USA, Israel, 11 April 2013

Oncology

Key words: p53 tumor suppressor, hepatic stellate cells, hepatocellular carcinoma, premalignant cells [more]

Oncogenic RAS pathway activation promotes resistance to anti-VEGF therapy through G-CSF–induced neutrophil recruitment

Vernon T Phan, Xiumin Wu, Jason H Cheng, Rebecca X Sheng, Alicia S Chung, Guanglei Zhuang, Christopher Tran, Qinghua Song, Marcin Kowanetz, Amy Sambrone, Martha Tan, Y Gloria Meng, Erica L Jackson, Franklin V Peale, Melissa R Junttila, Napoleone Ferrara

PNAS (PNAS) USA, 09 April 2013

Oncology

Key words: Agiogenesis microenvironment tyrosine kinase

Increased copy-number and not DNA hypomethylation causes overexpression of the candidate proto-oncogene CYP24A1 in colorectal cancer

Julia Höbaus, Doris M Hummel, Ursula Thiem, Irfete S Fetahu, Abhishek Aggarwal, Leonhard Müllauer, Gerwin Heller, Gerda Egger, Ildiko Mesteri, Sabina Baumgartner-Parzer, Enikö Kallay

International Journal of Cancer (Wiley) Austria, 05 April 2013

Oncology

Key words: CYP24A1, colorectal cancer, 20q13.2, methylation, proliferation [more]

Transcatheter delivery of sorafenib-eluting polylactide-co-glycolide microspheres: therapy response studies in a rat model of hepatocellular carcinoma

J Chen, A Sheu, RJ Lewandowski, RA Omary, L Shea, AC Larson

Journal of Vascular and Interventional Radiology (Elsevier) USA, 02 April 2013

Oncology

Key words: Sorafenib, hepatocellular carcinoma, polylactide-co-glycolide [more]

Excisional Wound Healing Is Delayed in a Murine Model of Chronic Kidney Disease

Akhil K Seth, Mauricio De la Garza, Robert C Fang, Seok J Hong, Robert D Galiano

PLoS One (PLOS) USA, 25 March 2013

Nephrology

Key words: Chronic kidney disease, wound healing, kidneys, granulation tissue, angiogenesis, inflammation, renal failure, surgical and invasive medical procedures [more]

Effects of Cholic Acid and its Derivatives in Experimental Arthritis

Silvia Hayer, Emina Halilbasic, Birgit Niederreiter, Martin Willburger, Peter Mandl, Victoria Saferding, Stephan Blüml, Josef Smolen, Michael Trauner, Kurt Redlich

Annals of the Rheumatic Diseases (BMJ Journals) Austria, 20 March 2013

Rheumatology

Key words: Cholesterol metabolism, Collagen-induced arthritis, nor-ursodeoxycholic acid [more]

Do High Molecular Weight Adiponectin Levels Associate with Radiographic Progression in early Rheumatoid Arthritis and Hand Osteoarthritis?

IR Klein-Wieringa, SN Andersen, JC Kwekkeboom, L Herb-vToorn, AHM van der Helm-van Mil, I Meulenbelt, TWJ Huizinga, M Kloppenburg, REM Toes, A Ioan-Facsinay

Annals of the Rheumatic Diseases (BMJ Journals) The Netherlands, 20 March 2013

Rheumatology

Key words: Adipokines, osteoarthritis, rheumatoid arthritis [more]

The prognostic value of estrogen receptor beta and proline-, glutamic acid- and leucine-rich protein 1 (PELP1) expression in ovarian cancer

Stefanie Aust, Peter Horak, Dietmar Pils, Sophie Pils, Christoph Grimm, Reinhard Horvat, Dan Tong, Bernd Schmid, Paul Speiser, Alexander Reinthaller, Stephan Polterauer

BMC Cancer (Springer) Austria, 14 March 2013

Oncology

Key words: Mucinous ovarian cancer, residual tumor load, mucinous eoc, eoc tissue, serous eoc, clear cell carcinoma, endometrioid tumor, breast cancer tissue, cytoreductive surgery, human eoc, endometrial cancer, serum ca-125, paraaortic lymphadenectomy, undifferentiated carcinoma, surgical staging [more]