Customer Publications (A total of 2600 papers published)
Tumor-associated B-cells induce tumor heterogeneity and therapy resistance
Nature Communications (Nature) USA, Austria, 19 September 2017
Oncology
Key words: Melanoma, oncogenic BRAFV600E, growth factor FGF-2, [more]
Organism: Human
Tissue: Skin, Lymphoid Tissue
Pathological State: Cancer
Development of a radiolabeled caninized anti-EGFR antibody for comparative oncology trials
Oncotarget (Impact Journals) Austria, 15 September 2017
Oncology
Key words: epidermal growth factor receptor, radio-immunotherapy, canine mammary carcinoma, canine antibody, comparative oncology [more]
Organism: Dog
Tissue: Breast
Pathological State: Cancer
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) promotes EGF receptor signaling of oral squamous cell carcinoma metastasis via the complex N-glycosylation
Oncogene (Nature) Taiwan, 11 September 2017
Oncology
Key words: Glycosylation, CEACAM6, OSCC (oral squamous cell carcinoma), EGFR [more]
Organism: Human
Pathological State: Cancer
Cell Line: OC-2 and OEC-M1 cells
The Novel Compound Sul-121 Preserves Endothelial Function and Inhibits Progression of Kidney Damage in Type 2 Diabetes Mellitus in Mice
Scientific Reports (Nature) The Netherlands, 11 September 2017
Nephrology
Key words: Type 2 diabetes mellitus (T2DM), diabetic nephropathy, Sul-121, glomerular fibronectin expression [more]
Organism: Mouse
Tissue: Kidney
Pathological State: Diabetes
A green tea polyphenol epigallocatechin-3-gallate enhances neuroregeneration after spinal cord injury by altering levels of inflammatory cytokines
Neuropharmacology (Elsevier) Czech Republic, 09 September 2017
Neuroscience
Key words: EGCG, green tea, spinal cord injury, neuroregeneration, cytokines, neuroprotection, p65NFkB [more]
Organism: Rat
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
579 High-risk human papillomavirus infection in Bowen's disease and Squamous Cell Carcinomas of the hands
Journal of Investigative Dermatology (Elsevier) Austria, 08 September 2017
Dermatology
Key words: Papillomavirus infection, Bowen's disease, squamous cell carcinomas [more]
Organism: Human
Tissue: Skin
Pathological State: Bowen's Disease, Cancer
Exploring Metabolic Configurations of Single Cells within Complex Tissue Microenvironments
Cell Metabolism (Elsevier) Austria, 07 September 2017
Cell Biology
Key words: Metabolic configuration, single cell, intracellular metabolism, intercellular metabolism, enzyme histochemistry, microenvironment, immunometabolism, cancer metabolism, metabolic biomarke, metabolic imaging method [more]
Organism: Mouse, Human
Tissue: Liver, Muscle, Colon, Breast
Pathological State: Cancer
4103Validation of cardiac magnetic resonance T1 mapping in cardiac amyloidosis
European Heart Journal (Oxford University Press) Austria, 29 August 2017
Cardiology
Key words: cardiac amyloidosis, cardiac mri [more]
Organism: Human
Tissue: Heart
Pathological State: Cardiac Amyloidosis
Placental Dysfunction Underlies Increased Risk of Fetal Growth Restriction and Stillbirth in Advanced Maternal Age Women
Scientific Reports (Nature) UK, 29 August 2017
Reproductive Medicine
Key words: Ageing, disease model, intrauterine growth, reproductive disorders [more]
Organism: Human
Tissue: Placenta
Selective targeting of a novel vasodilator to the uterine vasculature to treat impaired uteroplacental perfusion in pregnancy
Theranostics (NCBI) UK, USA, Estonia, Italy, 29 August 2017
Reproductive Medicine
Key words: pregnancy, placenta, nitric oxide, endothelium, vascular biology, drug targeting [more]
Organism: Mouse
Tissue: Placenta
Loss of host-derived osteopontin creates a glioblastoma-promoting microenvironment
Neuro-Oncology (Oxford University Press) USA, Germany, 26 August 2017
Oncology
Key words: glioblastoma, microglia, macrophage, osteopontin, SPP1, glioblastoma cd45 antigens macrophage-1 antigen macrophages microglia monocytes brain mice neoplasms osteopontin [more]
Organism: Human
Pathological State: Cancer
Cell Line: Ki67 cells
Combination of cuprizone and experimental autoimmune encephalomyelitis to study inflammatory brain lesion formation and progression
GLIA (Wiley) Germany, 24 August 2017
Neuroscience
Key words: Brain-intrinsic degenerative cascades, multiple sclerosis, Cup/EAE model [more]
Organism: Mouse
Tissue: Brain
Pathological State: Encephalomyelitis
Tumor-Associated Macrophages Promote Epigenetic Silencing of Gelsolin through DNA Methyltransferase 1 in Gastric Cancer Cells
Cancer Immunology Research (AACR Publications) Taiwan, 23 August 2017
Oncology
Key words: Tumor suppressor gelsolin (GSN), gastric cancer, DNA methylation [more]
Organism: Human
Tissue: Endometrium
Pathological State: Cancer
Zika virus infects renal proximal tubular epithelial cells with prolonged persistency and cytopathic effects
Emerging Microbes & Infections (Nature) China, 23 August 2017
Immunology, Virology
Key words: Cytopathic effects, prolonged persistency, renal proximal tubular epithelial cells, urinary system, Zika virus [more]
Organism: Mouse
Tissue: Kidney
Pathological State: Zika Virus Infection, Guillain–Barré syndrome
Efficient cell death induction in human glioblastoma cells by photodynamic treatment with Tetrahydroporphyrin-Tetratosylat (THPTS) and ionizing irradiation
Oncotarget (Impact Journals) Germany, Belarus, 23 August 2017
Oncology
Key words: photodynamic therapy, glioblastoma, THPTS, combination, ionizing radiation [more]
Organism: Human
Cell Line: Human authenticated GBM cell lines (A-172, U-87 MG, and DBTRG-05MG)
Reactive oxygen species–mediated switching expression of MMP-3 in stromal fibroblasts and cancer cells during prostate cancer progression
Scientific Reports (Nature) Taiwan, 22 August 2017
Oncology
Key words: Stromelysin 1 (MMP-3) and 2 (MMP-10), prostate cancer-associated stromal fibroblasts (CAFs), extracellular matrix (ECM) [more]
Organism: Human
Tissue: Prostate
Pathological State: Cancer
Screening platform for cell contact guidance based on inorganic biomaterial micro/nanotopographical gradients
Applied Materials and Interfaces (ACS Publications) The Netherlands, 21 August 2017
Stem Cell Research
Key words: Biomimetic surface, high-throughput screening, inorganic biomaterials, stem cell behavior, topographical gradient [more]
Organism: Human
Cell Line: Mesenchymal stem cells from human bone marrow (hBM-MSCs)
Bifidobacterium Infantis Ameliorates Chemotherapy-Induced Intestinal Mucositis Via Regulating T Cell Immunity in Colorectal Cancer Rats
Cellular Physiology and Biochemistry (Karger) China, 18 August 2017
Oncology
Key words: Bifidobacterium infantis, intestinal mucositis, 5-fluorouracil, oxaliplatin, CD4+CD25+Foxp3+ Tregs, CD4+CD17A+ cells, colorectal cancer [more]
Organism: Rat
Tissue: Allograft Tumor
Pathological State: Cancer
An Integrated Systems Biology Approach Identifies TRIM25 as a Key Determinant of Breast Cancer Metastasis
Cell Reports (Cell Press) USA, 15 August 2017
Oncology
Key words: ARACNe, MARINa, VIPER, breast, cancer, metastasis, transcription, TRIM25, EFP [more]
Organism: Mouse
Tissue: Allograft Tumor, Lung
Pathological State: Cancer
Impact of Type III Secretion Effectors and of Phenoxyacetamide Inhibitors of Type III Secretion on Abscess Formation in a Mouse Model of Pseudomonas aeruginosa Infection
Antimicrobial Agents and Chemotherapy (American Society for Microbiology) USA, 14 August 2017
Microbiology
Key words: Pseudomonas aeruginosa, abscesses, neutrophils, phenoxyacetamide inhibitors, type III secretion [more]
Organism: Mouse
Tissue: Liver, Spleen
Pathological State: Abscess
Effects of sulfur mustard on mesenchymal stem cells
Toxicology Letters (Elsevier) Germany, 14 August 2017
Toxicology
Key words: Sulfur mustard, mesenchymal stem cells, senescence, apoptosis, proliferation [more]
Organism: Human
Cell Line: Mesenchymal stem cells from human bone marrow (hBM-MSCs)
Attenuation of Follicular Helper T Cell–Dependent B Cell Hyperactivity by Abatacept Treatment in Primary Sjögren's Syndrome
Arthritis & Rheumatology (Wiley) The Netherlands, 13 August 2017
Rheumatology
Key words: CTLA-4Ig, CD4+ T cell, Sjögren's syndrome, marker ICOS [more]
Organism: Human
Pathological State: Sjögren's Syndrome
Role of glial-cell-derived neurotrophic factor in salivary gland stem cell response to irradiation
Radiotherapy and Oncology (Elsevier) The Netherlands, 04 August 2017
Oncology
Key words: Salivary glands, GDNF, stem cells, spheres, radiation-induced xerostomia [more]
Organism: Human
Tissue: Salivary Gland
Traditional Chinese medicine Danggui Buxue Tang inhibits colorectal cancer growth through induction of autophagic cell death
Oncotarget (Impact Journals) Taiwan, 03 August 2017
Oncology
Key words: Danggui Buxue Tang, colorectal cancer, autophagy, traditional Chinese medicine, mammalian target of rapamycin (mTOR) [more]
Organism: Mouse
Tissue: Colon, Xenograft Tumor
Pathological State: Cancer
The Prognostic Role of T1 Mapping Sequences: Can T1 Mapping Parameters Have a Role in Risk Stratification?
Cardiovascular Imaging Asia (Kamje Press) South Korea, 31 July 2017
Cardiology
Key words: Cardiac magnetic resonance imaging, T1 mapping, Prognosis [more]
Organism: Human
Tissue: Heart
Inhibition of colony stimulating factor-1 receptor abrogates microenvironment-mediated therapeutic resistance in gliomas
Oncogene (Nature) USA, Switzerland, 31 July 2017
Oncology
Key words: Glioblastomas, tumor microenvironment (TME)-mediated extrinsic resistance, PDGF-B-driven proneural glioma mouse model [more]
Organism: Mouse
Tissue: Brain
Pathological State: Cancer
Parathyroid hormone regulates fates of murine osteoblast precursors in vivo
The Journal of Clinical Investigation (American Society for Clinical Investigation) USA, 31 July 2017
Stem Cell Research
Key words: Parathyroid hormone, osteoblast precursors, bone biology, stem cells [more]
Organism: Mouse
Tissue: Bone
Transglutaminase 2 Inhibition Reverses Mesenchymal Transdifferentiation of Glioma Stem Cells by Regulating C/EBPβ Signaling
Cancer Research (AACR Publications) South Korea, 28 July 2017
Oncology
Key words: Necrosis, glioblastoma, transglutaminase 2 (TGM2), transcription factors (TF) [more]
Organism: Mouse
Tissue: Brain
Pathological State: Cancer
Fasting metabolism modulates the interleukin-12/interleukin-10 cytokine axis
PLoS One (PLOS) Austria, 24 July 2017
Immunology
Key words: Cell metabolism, mammalian target of rapamycin (mTOR), interleukin (IL)-12 and anti-inflammatory IL-10 [more]
Organism: Mouse
Tissue: Liver, Spleen
CD103+ tumor-infiltrating lymphocytes are tumor-reactive intraepithelial CD8+ T cells associated with prognostic benefit and therapy response in cervical cancer
OncoImmunology (Taylor and Francis) The Netherlands, 24 July 2017
Oncology
Key words: CD103, cervical cancer, intraepithelial T cells, therapeutic vaccination, tumor-infiltrating lymphocytes [more]
Organism: Human
Tissue: Uterus
Pathological State: Cancer
Precision cut lung slices as test system for candidate therapeutics in organophosphate poisoning
Toxicology (Elsevier) Germany, 22 July 2017
Toxicology
Key words: Chemical warfare agents, nerve agents, pesticide, lung, PCLS, precision cut lung slices [more]
Organism: Rat
Tissue: Lung
Large-scale 3-dimensional quantitative imaging of tissues: state-of-the-art and translational implications
Translational Research (Elsevier) USA, 22 July 2017
Medical Imaging
Key words: 2D2 dimensional, 3D3 dimensional, LSM- light sheet microscopy, IHCS- imaging high content screening, VTEA -Volumetric tissue exploration and analysis, 3DTC-3 dimensional tissue cytometry
Neuron-Specific Fluorescence Reporter-Based Live Cell Tracing for Transdifferentiation of Mesenchymal Stem Cells into Neurons by Chemical Compound
Stem Cells International (Hindawi Publishing Corporation) South Korea, 20 July 2017
Stem Cell Research
Strategies to develop endogenous stem cell-recruiting bioactive materials for tissue repair and regeneration
Advanced Drug Delivery Reviews (Elsevier) USA, 19 July 2017
Regenerative Medicine
Key words: Stem cell homing, growth factor delivery, chemoattractant gradients, endothelialization, extracellular matrix, bone graft substitutes, myocardial regeneration [more]
Organism: Human
Cell Line: Human mesenchymal stem cells (hMSCs)
The c.1085A>G genetic variant of CSF1R gene regulates tumor immunity by altering the proliferation, polarization, and function of macrophages
Clinical Cancer Research (AACR Publications) Taiwan, 19 July 2017
Oncology
Key words: Tumor, CSF1R, low VEGF expression, altering the polarization and function of macrophages [more]
Organism: Human
Tissue: Colon, Ovaries, Endometrium
Pathological State: Cancer
Production of reactive persulfide species in chronic obstructive pulmonary disease
Thorax (BMJ Journals) Japan, 19 July 2017
Pulmonology
Key words: Oxidative Stress [more]
Organism: Human
Tissue: Lung
Pathological State: Chronic Obstructive Pulmonary Disease
MicroRNA 155-deficiency leads to decreased autoantibody levels and reduced severity of nephritis and pneumonitis in pristaneinduced lupus
PLoS One (PLOS) Austria, 18 July 2017
Immunology
Key words: Systemic lupus, miR155-deficient, PBS-injected mice, glomerulonephritis, pneumonitis [more]
Organism: Mouse
Tissue: Kidney
Pathological State: Lupus
Analysis of cysteine-X-cysteine motif chemokine ligands 9, 10, and 11, their receptor CXCR3, and their possible role on the recruitment of immune cells at the maternal–conceptus interface in pigs†
Biology of Reproduction (Oxford University Press) South Korea, 15 July 2017
Immunology
Key words: Pig, pregnancy, uterus, endometrium, CXCL9, CXCL10, CXCL11 [more]
Organism: Human
Tissue: Endometrium
Pathological State: Cancer
Expansion of BCR/ABL1+ cells requires PAK2 but not PAK1
British Journal of Haematology (Wiley) Austria, 14 July 2017
Oncology
Key words: The p21-activated kinases (PAKs), BCR/ABL1+ haematopoietic malignancy, leukaemic cells [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Placental homing peptide-microRNA inhibitor conjugates for targeted enhancement of intrinsic placental growth signaling
Theranostics (NCBI) UK, 14 July 2017
Reproductive Medicine
Key words: fetal growth restriction, IGF-II, microRNA, placenta, proliferation, pregnancy [more]
Organism: Human
Tissue: Placenta
RIP3 attenuates the pancreatic damage induced by deletion of ATG7
Cell Death & Disease (Nature) Germany, 13 July 2017
Gastroenterology
Key words: Pancreatitis, Rip3, acinar cells, autophagy and necroptosis [more]
Organism: Human, Mouse
Tissue: Pancreas
Small cell lung cancer: model of circulating tumor cell tumorospheres in chemoresistance
Scientific Reports (Nature) Austria, 13 July 2017
Oncology
Key words: Small cell lung cancer (SCLC), circulating tumor cells (CTCs), Ki67 and carbonic anhydrase 9 (CAIX) [more]
Organism: Human
Tissue: Lung
Pathological State: Cancer
Tailor-made purified human platelet lysate concentrated in neurotrophins for treatment of Parkinson's disease
Biomaterials (Elsevier) Taiwan, 12 July 2017
Biological Materials
Key words: Platelet lysate, neuroprotection, parkinson, MPTP, neurotrophins, growth factors [more]
Organism: Mouse
Tissue: Brain
CCAAT/enhancer-binding protein delta promotes intracellular lipid accumulation in M1 macrophages of vascular lesions
Cardiovascular Research (Oxford University Press) Taiwan, 11 July 2017
Cardiology
Key words: CEBPD, inflammation, macrophages, PTX3, statins [more]
Organism: Mouse
Pathological State: Vascular lesions
Cell Line: Macrophages and nile red-positive cells
Instructing cells with programmable peptide DNA hybrids
Nature Communications (Nature) USA, 10 July 2017
Cell Biology
Key words: Native extracellular matrix, peptide-DNA (P-DNA) [more]
Organism: Mouse
Cell Line: NIH-3T3 mouse embryonic fibroblasts
Synthetic lethal genetic interactions between Rad54 and PARP-1 in mouse development and oncogenesis
Oncotarget (Impact Journals) Italy, 07 July 2017
Oncology
Key words: cerebellum, expression profiles, medulloblastoma, apoptosis, senescence [more]
Organism: Mouse
Tissue: Brain
Pathological State: Cancer
A novel in vitro model of villitis of unknown etiology demonstrates altered placental hormone and cytokine profile
American Journal of Reproductive Immunology (Wiley) UK, 06 July 2017
Reproductive Medicine
Key words: Placental dysfunction, villitis of unknown etiology, T cell, fetal growth restriction [more]
Organism: Human
Cell Line: Placental explant culture
Tyrosine Kinase Expressed in Hepatocellular Carcinoma, TEC, Controls Pluripotency and Early Cell Fate Decisions of Human Pluripotent Stem Cells via Regulation of Fibroblast Growth Factor-2 Secretion
Stem Cells (Wiley) Czech Republic, 06 July 2017
Stem Cell Research
Key words: Human pluripotent stem cells (hPSCs), fibroblast growth factor (FGF) receptors, hepatocellular carcinoma (TEC) [more]
Organism: Human
Cell Line: hPSCs (Human pluripotent stem cells)
Increased migration of antigen presenting cells to newly-formed lymphatic vessels in transplanted kidneys by glycol-split heparin
PLoS One (PLOS) The Netherlands, 30 June 2017
Transplantation Medicine
Key words: Chronic renal transplant, lymphatic chemokine-proteoglycan, renal graft [more]
Organism: Rat
Tissue: Kidney
Pathological State: Chronic Transplant Dysfunction, Organ Transplantation
Keratinocytes produce IL-17c to protect peripheral nervous systems during human HSV-2 reactivation
Journal of Experimental Medicine (Rockefeller University Press) USA, 29 June 2017
Neuroscience
Key words: Herpes simplex virus (HSV), keratinocytes, IL-17c, nervous system [more]
Organism: Human
Tissue: Skin
Cell Line: Keratinocytes
Interaction of tankyrase and peroxiredoxin II is indispensable for the survival of colorectal cancer cells
Nature Communications (Nature) South Korea, 28 June 2017
Oncology
Key words: Colon cancer, mechanisms of disease [more]
Organism: Mouse
Tissue: Small Intestine
Hinokitiol up-regulates miR-494-3p to suppress BMI1 expression and inhibits self-renewal of breast cancer stem/progenitor cells
Oncotarget (Impact Journals) Taiwan, 27 June 2017
Oncology
Key words: hinokitiol, miR-494-3p, BMI1, breast cancer, cancer stem cells [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
The bile acid receptor FXR attenuates acinar cell autophagy in chronic pancreatitis
Cell Death Discovery (Nature) Germany, 19 June 2017
Gastroenterology
Key words: Apoptosis, chronic pancreatitis, macroautophagy, necroptosis [more]
Organism: Human, Mouse
Tissue: Pancreas
Pathological State: Pancreatitis
Breviscapine (BVP) inhibits prostate cancer progression through damaging DNA by minichromosome maintenance protein-7 (MCM-7) modulation
Biomedicine & Pharmacotherapy (Elsevier) China, 17 June 2017
Oncology
Key words: Breviscapine, human prostate cancer, DNA damage, MCM-7, Apoptosis [more]
Organism: Human, Mouse
Tissue: Prostate, Xenograft Tumor
Pathological State: Cancer
Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation
Molecular Cancer Therapeutics (AACR Publications) Czech Republic, 15 June 2017
Oncology
Key words: Tumor cells, serine threonine kinase, DNA antimetabolites [more]
Organism: Human, Mouse
Tissue: Skin, Xenograft Tumor
Pathological State: Cancer
Inhibition of the NOD-like receptor protein 3 inflammasome is protective in juvenile influenza A virus infection
Frontiers in Immunology (Frontiers Media S.A.) USA, 10 June 2017
Immunology
Key words: Inhibition of the NOD-Like Receptor Protein 3 Inflammasome Is Protective in Juvenile Influenza A Virus Infection [more]
Organism: Mouse
Tissue: Lung
Pathological State: Influenza Infection
Clinical significance of the estrogen-modifying enzymes steroid sulfatase and estrogen sulfotransferase in epithelial ovarian cancer
Oncology Letters (Spandidos Publications) Austria, Belgium, Germany, 03 June 2017
Oncology
Key words: pithelial ovarian cancer, estrogen, estrogen metabolizing enzymes, STS, sulfotransferase, SULT1E1, E2, ovarian cancer [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
Mutant Mice With Calcium-Sensing Receptor Activation Have Hyperglycemia That Is Rectified by Calcilytic Therapy
Endocrinology (Oxford University Press) UK, 02 June 2017
Endocrinology
Key words: Calcium-Sensing Receptor, CaSR, Hyperglycemia, Calcilytic Therapy, glucose homeostasis, Diabetes [more]
Organism: Mouse
Tissue: Xenograft Tumor, Pancreas
Pathological State: Cancer
Resveratrol Pretreatment Attenuates Concanavalin A-induced Hepatitis through Reverse of Aberration in the Immune Response and Regenerative Capacity in Aged Mice
Scientific Reports (Nature) Taiwan, 02 June 2017
Immunology, Virology
Key words: Age-related autoimmune hepatitis, cell senescence, apoptosis, concanavalin A (Con A), [more]
Organism: Mouse
Tissue: Liver
Extracellular matrix hydrogel derived from human umbilical cord as a scaffold for neural tissue repair and its comparison with extracellular matrix from porcine tissues
Tissue Engineering Part C (Mary Ann Liebert Inc.) Czech Republic, 01 June 2017
Regenerative Medicine
Key words: Hydrogel, Umbilical Cord, Neural Tissue Repair, Extracellular Matrix, Porcine Tissues [more]
Organism: Rat
Tissue: Spinal Cord
Cell Line: Dorsal root ganglia
Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation
Cell Reports (Cell Press) USA, 30 May 2017
Oncology
Key words: wild-type IDH1, GBM, metabolism, differentiation, NADPH, lipids, reactive oxygen species (ROS), EGFR, targeted therapy [more]
Organism: Mouse
Pathological State: Cancer
Cell Line: GIC-20 (Glioma initiating cells)
Automated Image Analysis of HER2 Fluorescence In Situ Hybridization to Refine Definitions of Genetic Heterogeneity in Breast Cancer Tissue
BioMed Research International (Hindawi Publishing Corporation) Lithuania, Austria, 28 May 2017
Medical Image Analysis
Key words: Automated Image Analysis, HER2 FISH, Genetic Heterogeneity, Breast Cancer [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
Galangin ameliorates cisplatin-induced nephrotoxicity by attenuating oxidative stress, inflammation and cell death in mice through inhibition of ERK and NF-kappaB signaling
Toxicology and Applied Pharmacology (Elsevier) China, 27 May 2017
Oncology
Key words: Cisplatin nephrotoxicity, ERK, Galangin, Inflammation, NF-κB, Oxidative stress [more]
Organism: Mouse
Tissue: Kidney
Pathological State: Acute Kidney Injury
Hepatic IFIT3 predicts interferon-α therapeutic response in patients of hepatocellular carcinoma
Hepatology (Wiley) China, 26 May 2017
Oncology
Key words: Adjuvant interferon-α (IFN-α), hepatocellular carcinoma (HCC), IFIT3, [more]
Organism: Human
Tissue: Liver
Pathological State: Cancer
QUICK FIRE CASES- SESSION III
European Heart Journal (Oxford University Press) Denmark, 25 May 2017
Cardiology
Key words: Myocardium, diagnosis, fire - disaster, s fire - physical, phenomenon cardiac, mri [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
SIRT3-Mediated Dimerization of IDH2 Directs Cancer Cell Metabolism and Tumor
Cancer Research (AACR Publications) USA, 23 May 2017
Oncology
Key words: Isocitrate dehydrogenase IDH2, α-ketoglutarate, cancer cells, SIRT3 [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
Single allele Lmbrd1 knockout results in cardiac hypertrophy
Journal of the Formosan Medical Association (Elsevier) Taiwan, 23 May 2017
Cardiology
Key words: Cardiac hypertrophy, Disease animal model, Gene knockout, Mouse Lmbrd1 gene, Human LMBRD1 gene, LMBD1 protein [more]
Organism: Mouse
Tissue: Heart
Pathological State: Cardiac Hypertrophy
MicroRNA-146a governs fibroblast activation and joint pathology in arthritis
Journal of Autoimmunity (Elsevier) Austria, 22 May 2017
Rheumatology
Key words: Synovial fibroblasts, miR-146a, tumor necrosis factor (TNF) receptor, factor 6 (TRAF6), osteoprotegerin (OPG) [more]
Organism: Human
Tissue: Bone
Pathological State: Rheumatoid Arthritis
Significance of B10 cell in patients with thymoma complicated with myasthenia gravis
Oncotarget (Impact Journals) China, 17 May 2017
Oncology
Key words: regulatory B cell, B10 cell, thymoma, myasthenia gravis, autoimmune abnormality [more]
Organism: Human
Tissue: Thymus
Pathological State: Cancer
Enhanced Bruton's Tyrosine Kinase Activity in Peripheral Blood B Lymphocytes From Patients With Autoimmune Disease
Arthritis & Rheumatology (Wiley) The Netherlands, 10 May 2017
Rheumatology
Key words: Bruton's tyrosine kinase (BTK), B cell receptor (BCR), Sjögren's syndrome (SS), BTK phosphorylation [more]
Organism: Human
Tissue: Salivary Gland
Pathological State: Sjögren's Syndrome
Hyaluronan keeps mesenchymal stem cells quiescent and maintains the differentiation potential over time
Aging Cell (Wiley) Taiwan, 04 May 2017
Stem Cell Research
Key words: Hyaluronan (HA), mesenchymal stem cells (MSCs), cellular aging, human placenta-derived MSCs (PDMSC) [more]
Organism: Human
Cell Line: Human mesenchymal stem cells (hMSCs)
CD1b-autoreactive T cells contribute to hyperlipidemia-induced skin inflammation in mice
The Journal of Clinical Investigation (American Society for Clinical Investigation) USA, 02 May 2017
Immunology
Key words: Autoimmunity, Immunology [more]
Organism: Mouse
Tissue: Heart, Skin
A novel histone deacetylase inhibitor TMU-35435 enhances etoposide cytotoxicity through the proteasomal degradation of DNA-PKcs in triple-negative breast cancer
Cancer Letters (Elsevier) Taiwan, 24 April 2017
Oncology
Key words: DNA damage, DNA repair, Ubiquitin–proteasome system, Triple-negative breast cancer [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Cytotoxicity of Natural Killer Cells Activated Through NKG2D Contributes to the Development of Bronchiolitis Obliterans in a Murine Heterotopic Tracheal Transplant Model
American Journal of Transplantation (Wiley) Japan, 21 April 2017
Transplantation Medicine
Key words: Basic (laboratory) research/science, lung transplantation/pulmonology, bronchiolitis obliterans (BOS), natural killer (NK) cells/NK receptors [more]
Organism: Mouse
Tissue: Lung
Pathological State: Organ Transplantation
Two different, mutually exclusively distributed, TP53 mutations in ovarian and peritoneal tumor tissues of a serous ovarian cancer patient: indicative for tumor origin?
Molecular Case Studies (CSH Press) Austria, 14 April 2017
Oncology
Key words: Mutually exclusive p53 mutations in ovarian cancer [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
Immunomodulatory Magnetic Microspheres for Augmenting Tumor-Specific Infiltration of Natural Killer (NK) Cells
Applied Materials and Interfaces (ACS Publications) USA, 13 April 2017
Oncology
Key words: And image-guided therapy, cancer immunotherapy interferon-gamma (IFN-γ), microspheres, natural killer (NK) cells infiltration [more]
Organism: Human
Extravillous Trophoblast and Endothelial Cell Crosstalk Mediates Leukocyte Infiltration to the Early Remodeling Decidual Spiral Arteriole Wall
The Journal of Immunology (American Association of Immunologists) UK, Canada, 10 April 2017
Immunology
Key words: Decidual spiral arteriole (SpA), uterine decidual NK (dNK) cells, extravillous trophoblasts (EVTs), chemokines [more]
Organism: Human
Tissue: Endometrium
EGFR in Tumor-associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients
Gastroenterology (Elsevier) Austria, 09 April 2017
Oncology
Key words: Tumor microenvironment, cytokine, CRC, colon cancer [more]
Organism: Human, Mouse
Tissue: Colon
Pathological State: Cancer
Dose-escalation study for the targeting of CD44v+ cancer stem cells by sulfasalazine in patients with advanced gastric cancer (EPOC1205)
Gastric Cancer (Springer) Japan, 07 April 2017
Oncology
Key words: Cancer stem cell, CD44 variant positive, Gastric cancer, Sulfasalazine xCT [more]
Organism: Human
Tissue: Stomach
Pathological State: Cancer
Surviving murine experimental sepsis affects the function and morphology of the inner ear
Biology Open (The Company of Biologists) Austria, 04 April 2017
Physiology
Key words: Sepsis, Hearing loss, Inner ear, Inflammation, Apoptosis [more]
Organism: Mouse
Pathological State: Sepsis
Intracerebral delivery of the M2 polarizing cytokine interleukin 13 using mesenchymal stem cell implants in a model of temporal lobe epilepsy in mice
Official Journal of the International League Against Epilsepy (Wiley) Belgium, 04 April 2017
Transplantation Medicine
Key words: IL-13 MSCs, acid–induced status epilepticus, video–electroencephalography, F4/80+ cells [more]
Organism: Mouse
Tissue: Brain
Pathological State: Epilepsy
Information Limits of Optical Microscopy: Application to Fluorescent Labelled Tissue Section
Bioinformatics and Biomedical Engineering (Springer) Austria, Czech Republic, 01 April 2017
Microscopy
Key words: Electromagnetic centroid, Point divergence gain, Superresolution, 3D structure reconstruction [more]
Organism: Human
Tissue: Prostate
Pathological State: Cancer
High expression of CASZ1 is associated with poor prognosis in ovarian cancer
Cancer Research (AACR Publications) Taiwan, 01 April 2017
Oncology
Key words: High expression of CASZ1 is associated with poor prognosis in ovarian cancer [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
Brilliant Blue G, but not Fenofibrate, Treatment Reverts Hemiparkinsonian Behavior and Restores Dopamine Levels in an Animal Model of Parkinson's Disease
Cell Transplantation (SAGE Journals) Brazil, 01 April 2017
Neuroscience
Key words: Parkinson's disease (PD), P2X7 receptor, brilliant Blue G (BBG), PGC-1α, fenofibrate [more]
Organism: Rat
Tissue: Brain
ICAM-1 binding rhinoviruses enter HeLa cells via multiple pathways and travel to distinct intracellular compartments for uncoating
Viruses (MDPI) Austria, 01 April 2017
Virology
Key words: human rhinoviruses, ICAM-1, productive uncoating, endocytosis, clathrin, dynamin, macropinocytosis, actin, dynein [more]
Organism: Human
Pathological State: Virus Infection
Cell Line: HeLA cells
Colibactin contributes to the hypervirulence of pks+ K1 CC23 Klebsiella pneumoniae in mouse meningitis infections
Frontiers in Cellular and Infection Microbiology (Frontiers Media S.A.) Taiwan, 31 March 2017
Microbiology
Key words: Colibactin, pks+ K1 CC23 Klebsiella pneumoniae, Mouse Meningitis [more]
Organism: Mouse
Tissue: Small Intestine, Colon, Liver, Spleen, Brain
Pathological State: Klebsiella Infection, Meningitis
Early, but not late treatment with human umbilical cord blood-derived mesenchymal stem cells attenuates cisplatin nephrotoxicity through immunomodulation
American Journal of Physiology (APS Journals) South Korea, 29 March 2017
Physiology
Key words: Acute kidney injury, Cisplatin nephrotoxicity, immunomodulation, mesenchymal stem cells, regulatory T cells [more]
Organism: Mouse
Tissue: Kidney
Pathological State: Acute Kidney Injury
HDAC1-3 inhibitor MS-275 enhances IL10 expression in RAW264.7 macrophages and reduces cigarette smoke-induced airway inflammation in mice
Scientific Reports (Nature) The Netherlands, 27 March 2017
Immunology
Key words: Mechanism of action, Pharmacodynamics [more]
Organism: Mouse
Tissue: Lung
Pathological State: Inflammation
Non-thermal air plasma promotes the healing of acute skin wounds in rats
Scientific Reports (Nature) Czech Republic, 24 March 2017
Regenerative Medicine
Key words: Non-thermal plasma (NTP), skin wound, atmospheric pressure air plasma, histological and gene expression analysis [more]
Organism: Rat
Tissue: Skin
Pathological State: Skin Wound
Janus-faced Acrolein prevents allergy but accelerates tumor growth by promoting immunoregulatory Foxp3+ cells: Mouse model for passive respiratory exposure
Scientific Reports (Nature) Austria, 23 March 2017
Immunology
Key words: Acrolein, BALB/c allergy model, T cells, D2F2 tumor cells [more]
Organism: Mouse
Tissue: Lung, Spleen, Allograft Tumor
Pathological State: Cancer
Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas
The Journal of Clinical Investigation (American Society for Clinical Investigation) USA, Germany, 20 March 2017
Oncology, Immunology
Key words: Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas [more]
Organism: Mouse
Tissue: Brain
Pathological State: Cancer
Histone Methyltransferase G9a Drives Chemotherapy Resistance by Regulating the Glutamate–Cysteine Ligase Catalytic Subunit in Head and Neck Squamous Cell Carcinoma
Molecular Cancer Therapeutics (AACR Publications) Taiwan, 06 March 2017
Oncology
Key words: Neck squamous cell carcinomas (HNSCC), histone methyltransferase, apoptosis, glutamate-cysteine ligase catalytic subunit (GCLC) [more]
Organism: Mouse
Tissue: Head and Neck
Pathological State: Cancer
Cordycepin induces human lung cancer cell apoptosis by inhibiting nitric oxide mediated ERK/Slug signaling pathway
American Journal of Cancer Research (NCBI) South Korea, USA, 01 March 2017
Oncology
Key words: Cordycepin, nitric oxide, ERK, slug, lung cancer, apoptosis [more]
Organism: Human
Pathological State: Cancer
Cell Line: Human lung adenocarcinoma cell lines, A549 and PC9
Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways
Journal of Hematology & Oncology (Springer) Taiwan, Vietnam, 28 February 2017
Oncology
Key words: M2 tumor-associated macrophages, Colon tumorigenesis, Stemness, YAP1, Ovatodiolide [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Antibodies against nonstructural protein 1 protect mice from dengue virus-induced mast cell activation
Laboratory Investigation (Nature) Taiwan, 27 February 2017
Immunology, Virology
Key words: Dengue virus, mast cells, DHF/DSS, chemokines [more]
Organism: Mouse
Tissue: Skin
Pathological State: Dengue Virus Infection
Tumor specific regulatory T cells in the bone marrow of breast cancer patients selectively upregulate the emigration receptor S1P1
Cancer Immunology, Immunotherpay (Springer) Germany, 21 February 2017
Oncology
Key words: Antigen-specific regulatory T cells, Bone marrow, Sphingosine-1-phosphate receptor 1, Exit, Breast cancer patients [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
Ccdc181 is a microtubule binding protein that interacts with Hook1 in haploid male germ cells and localizes to the sperm tail and motile cilia
European Journal of Cell Biology (Elsevier) Austria, 20 February 2017
Cell Biology
Key words: Ccdc181, Cilia, Manchette, Microtubules, Motility, Hook1, Spermatogenesis [more]
Organism: Mouse
Tissue: Testis, Lung, Trachea, Brain
Diagnostic and prognostic relevance of CP2c and YY1 expression in hepatocellular carcinoma
Oncotarget (Impact Journals) South Korea, USA, 17 February 2017
Oncology
Key words: hepatocellular carcinoma (HCC), CP2c, YY1, diagnosis, prognosis [more]
Organism: Human
Tissue: Liver
Pathological State: Cancer
Suppression of TAK1 pathway by shear stress counteracts the inflammatory endothelial cell phenotype induced by oxidative stress and TGF-β1
Scientific Reports (Nature) The Netherlands, 17 February 2017
Immunology
Key words: Endothelial dysfunction, TAK1 (MAP3K7), ERK5 (MAPK7), TGF-β [more]
Organism: Human
Cell Line: HUVECs (Human umbilical vein endothelial cells)
Subcellular probes for neurochemical recording from multiple brain sites
Lab on a Chip (Royal Society of Chemistry) USA, 15 February 2017
Nanomedicine
Key words: striatum, voltammetry, implantable sensors, microelectrodes, dopamine [more]
Organism: Rat
Tissue: Brain
Editor's highlight: periodic exposure to smartphone-mimic low-luminance blue light induces retina damage through Bcl-2/BAX-dependent apoptosis
Toxicological Sciences (Oxford University Press) Taiwan, 10 February 2017
Toxicology
Key words: blue light, age-related macular degeneration, apoptosis, Bax, Bcl-2, FasL, caspase-3. [more]
Organism: Rat
Tissue: Eye
The lymphatic phenotype of lung allografts in patients with bronchiolitis obliterans syndrome and restrictive allograft syndrome
Transplantation (Wolters Kluwer) Austria, 10 February 2017
Transplantation Medicine
Key words: Lymphatic Phenotype, Lung Allograft, Bronchiolitis Obliterans Syndrome, Restrictive Allograft Syndrome [more]
Organism: Human
Tissue: Lung
Pathological State: Bronchiolitis
Elatoside C protects against ox-LDL-induced HUVECs injury by FoxO1-mediated autophagy induction
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (Elsevier) China, 09 February 2017
Neuroscience
Key words: Autophagy, apoptosis, Elatoside C, ox-LDL, FoxO1, HUVECs [more]
Organism: Human
Cell Line: HUVECs (Human umbilical vein endothelial cells)
Anti-leukemia effects of the novel synthetic 1-benzylindole derivative 21-900 in vitro and in vivo
Scientific Reports (Nature) Taiwan, 09 February 2017
Oncology
Key words: Histone deacetylase (HDAC), cell lines HL-60 and MOLT-4, apoptosis [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Diffusion radiomics analysis of intratumoral heterogeneity in a murine prostate cancer model following radiotherapy: Pixelwise correlation with histology
Journal Of Magnetic Resonance Imaging (Wiley) Taiwan, 08 February 2017
Oncology
Key words: Apparent diffusion coefficient (ADC), TRAMP-C1, tumor, [more]
Organism: Mouse
Tissue: Allograft Tumor
Pathological State: Cancer
Targeting Extracellular Cyclophilin A Reduces Neuroinflammation and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis
Journal of Neuroscience (Society for Neuroscience) Italy, 08 February 2017
Neuroscience
Key words: Amyotrophic lateral sclerosiscy, clophilin A, neuroinflammation [more]
Organism: Mouse
Tissue: Spinal Cord
Pathological State: Amyotrophic Lateral Sclerosis
Theranostic Nucleic Acid Binding Nanoprobe Exerts Anti-inflammatory and Cytoprotective Effects in Ischemic Injury
Theranostics (NCBI) USA, 08 February 2017
Cardiology
Key words: NA, RNA, Inflammation, Ischemia, Nanoprobe, Imaging. [more]
Organism: Mouse
Tissue: Heart
Pathological State: Myocardial Ischemia
Laser deposition of poly(3-hydroxybutyric acid-co-3-hydroxyvaleric acid) − Lysozyme microspheres based coatings with anti-microbial properties
International Journal of Pharmaceutics (Elsevier) Romania, 07 February 2017
Regenerative Medicine
Key words: Lysozyme, Laser processing, MAPLE thin coatings, Antimicrobial surfaces, Osteoblast and endothelial cell culture [more]
Organism: Human
Pathological State: Cancer
Cell Line: SAOS2 cells (primary osteogenic sarcoma cells)
Tumour-infiltrating regulatory T cell density before neoadjuvant chemoradiotherapy for rectal cancer does not predict treatment response
Oncotarget (Impact Journals) Australia, 03 February 2017
Oncology
Key words: Rectal cancer, regulatory T cells, radiotherapy, chemotherapy, treatment response [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Abstract P2-04-07: Immune profiling of post neoadjuvant high metastatic risk (RCB-II/III) residual disease in patients with early triple negative breast cancers
Cancer Research (AACR Publications) UK, 01 February 2017
Oncology
Organism: Human
Tissue: Breast
Pathological State: Cancer
Biocomposite coatings based on Poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/calcium phosphates obtained by MAPLE for bone tissue engineering
Applied Surface Science (Elsevier) Romania, 31 January 2017
Regenerative Medicine
Key words: MAPLE, Calcium phosphates, PHBV, Composite, Hydroxyapatite, β-Tricalcium phosphate [more]
Organism: Human
Cell Line: Human mesenchymal stem cells (hMSCs)
Orthogonal ubiquitin transfer identifies ubiquitination substrates under differential control by the two ubiquitin activating enzymes
Nature Communications (Nature) USA, 31 January 2017
Cell Biology
Key words: Protein ubiquitination, mammalian cells, polyubiquitination [more]
Organism: Human
Cell Line: MCF-10A cells ( human female mammary gland cells)
Effect of a cocoa diet on the small intestine and gut-associated lymphoid tissue composition in an oral sensitization model in rats ☆
The Journal of Nutritional Biochemistry (Elsevier) Spain, 23 January 2017
Gastroenterology
Key words: Cholera toxin, Cocoa, Ovalbumin, TCRγδ+ cells, Tolerance [more]
Organism: Rat
Tissue: Small Intestine
SOX2 and Rb1 in esophageal small-cell carcinoma: their possible involvement in pathogenesis
Modern Pathology (Nature) Japan, 20 January 2017
Pathology
Key words: Esophageal small-cell carcinoma, SOX2 overexpression, squamous-basal markers (CK5/6 and p40), glandular markers (CK18 and CEA) [more]
Organism: Human
Tissue: Esophagus
Pathological State: Cancer
Chronic signaling via the metabolic checkpoint kinase mTORC1 induces macrophage granuloma formation and marks sarcoidosis progression
Nature Immunology (Nature) Austria, 16 January 2017
Pathology
Key words: Hypertrophic macrophages, tuberous sclerosis 2 (Tsc2), mTORC1 [more]
Organism: Mouse
Tissue: Lung
Pathological State: Sarcoidosis
Cordycepin induces apoptosis by caveolin-1-mediated JNK regulation of Foxo3a in human lung adenocarcinoma
Oncotarget (Impact Journals) South Korea, USA, 14 January 2017
Oncology
Key words: cordycepin, CAV1, JNK, Foxo3a, apoptosis [more]
Organism: Human
Pathological State: Cancer
Cell Line: human lung adenocarcinoma lines A549, HCC827, and PC9
Development of a DsRed-expressing HepaRG cell line for real-time monitoring of hepatocyte-like cell differentiation by fluorescence imaging, with application in screening of novel geometric microstructured cell growth substrates
Biomedical Microdevices (Springer) Romania, 09 January 2017
Biological Methods
Key words: HepaRG, Hepatocyte-like cells, HBV, Differentiation, Microstructured PDMS [more]
Organism: Human
Cell Line: HepaRG, HeLa, Me290 cells
Inhibition of the transcriptional repressor complex Bcl-6/BCoR induces endothelial sprouting but does not promote tumor growth
Oncotarget (Impact Journals) Austria, 03 January 2017
Oncology
Key words: 79-6, Bcl-6, BCoR, colorectal carcinoma, vascular sprouting [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Limited tumor tissue drug penetration contributes to primary resistance against angiogenesis inhibitors
Theranostics (NCBI) Hungary, Austria, Sweden, 01 January 2017
Oncology
Key words: matrix assisted laser desorption ionization, imaging mass spectrometry, angiogenesis, receptor tyrosine kinase inhibitor, resistance, cancer [more]
Organism: Mouse
Tissue: Colon
Pathological State: Cancer
Heme Oxygenase-1-Expressing Dendritic Cells Promote Foxp3+ Regulatory T Cell Differentiation and Induce Less Severe Airway Inflammation in Murine Models
PLoS One (PLOS) Taiwan, 29 December 2016
Immunology
Key words: Dendritic cells (DCs), HO-1, lipopolysaccharide (LPS), Foxp3+ [more]
Organism: Mouse
Tissue: Lung
Interstitial Fibrosis, Functional Status, and Outcomes in Heart Failure With Preserved Ejection Fraction
Circulation:Cardiovascular Imaging (AHA Journals) Austria, 14 December 2016
Cardiology
Key words: Magnetic resonance imaging, heart failure, mapping [more]
Organism: Human
Tissue: Heart
Pathological State: Heart Failure
Adipose tissue–derived mesenchymal stem cells expressing prodrug-converting enzyme inhibit human prostate tumor growth
Molecular Therapy (Cell Press) Austria, Slovakia, 14 December 2016
Stem Cell Research
Mesenchymal Stem Cells Correct Inappropriate Epithelial–mesenchyme Relation in Pulmonary Fibrosis Using Stanniocalcin-1
Molecular Therapy (Cell Press) Japan, 14 December 2016
Pulmonology
Key words: Mesenchymal Stem Cells, Epithelial–mesenchyme Relation, Pulmonary Fibrosis, Stanniocalcin-1 [more]
Organism: Mouse
Tissue: Lung
Pathological State: Pulmonary Fibrosis
Early dissemination seeds metastasis in breast cancer
Nature (Nature) Germany, 14 December 2016
Oncology
Key words: Metastatic dissemination, breast cancer, HER2, Karyotypic and phenotypic analysis [more]
Organism: Mouse
Tissue: Breast
Pathological State: Cancer
Cell-Based Delivery of Interleukin-13 Directs Alternative Activation of Macrophages Resulting in Improved Functional Outcome after Spinal Cord Injury
Stem Cell Reports (Elsevier) Belgium, 13 December 2016
Transplantation Medicine
Key words: Mesenchymal stem cells, interleukin-13, spinal cord injury, cell transplantation, microglia, macrophages [more]
Organism: Mouse
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
The 6-chromanol derivate SUL-109 enables prolonged hypothermic storage of adipose tissue-derived stem cells
Biomaterials (Elsevier) The Netherlands, 09 December 2016
Biological Materials
Key words: Adipose tissue-derived stem cells (ASC), Hypothermia, Cold storage, Mitochondrial damage, Chromanol [more]
Organism: Human
Cell Line: Adipose tissue derived stromal cells (ADSC)
Involvement of Pancreatic Stellate Cells in Regeneration of Remnant Pancreas after Partial Pancreatectomy
PLoS One (PLOS) Japan, 09 December 2016
Regenerative Medicine
Key words: Pancreatectomy, siRNA, activated pancreas stellate cells (aPSCs), apoptosis [more]
Organism: Rat
Tissue: Pancreas
Nrf2 exerts cell-autonomous antifibrotic effects: compromised function in systemic sclerosis and therapeutic rescue with a novel heterocyclic chalcone derivative
Translational Research (Elsevier) USA, 09 December 2016
Neuroscience
Key words: Nrf2-nuclear factor erythroid 2–related factor 2, systemic sclerosis, TGF-β, CDDO, TMC [more]
Organism: Human
Tissue: Skin
Pathological State: Systemic Sclerosis
Lead-Free Piezoelectric (Ba,Ca)(Zr,Ti)O3 Thin Films for Biocompatible and Flexible Devices
Applied Materials and Interfaces (ACS Publications) Romania, 08 December 2016
Biological Materials
Key words: Biocompatible materials, laser processing, lead-free thin films, mesenchymal stem cells, osteogenic differentiation [more]
Organism: Human
Pathological State: Cancer
Cell Line: HEK 293T and A375 cells (Human epithelial embryonic kidney and human malignant melanoma cells)
Silica-Coated Metal Chelating-Melanin Nanoparticles as a Dual-Modal Contrast Enhancement Imaging and Therapeutic Agent
Applied Materials and Interfaces (ACS Publications) USA, 08 December 2016
Nanomedicine
Key words: Fluorescence imaging, melanin, metal-chelation, MRI, multimodal image-guidance, silica coating [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Nodal metastasis signatures in breast cancer
Pathology-Research and Practice (Elsevier) South Korea, 05 December 2016
Oncology
Key words: Breast cancer, node positive ratio, node positive number, ERK, WDR1, c-MET [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
Solid stress and elastic energy as measures of tumour mechanopathology
Nature Biomedical Engineering (Nature) USA, 28 November 2016
Neuroscience
Key words: Solid stress, tissue stiffness, tumour [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Mast Cells Are Abundant in Primary Cutaneous T-Cell Lymphomas: Results from a Computer-Aided Quantitative Immunohistological Study
PLoS One (PLOS) Austria, 28 November 2016
Oncology
Key words: Mast cells, cutaneous T-cell lymphomas (CTCL), haematopoetic cells [more]
Organism: Human
Tissue: Skin
Pathological State: Cancer
Cardiac extracellular matrix is associated with adverse outcome in patients with chronic heart failure
European Journal of Heart Failure (Wiley) Austria, 27 November 2016
Cardiology
Key words: Extracellular matrix (ECM), heart failure (HF), endomyocardial biopsy [more]
Organism: Human
Tissue: Heart
Pathological State: Heart Failure
Antimicrobial polycaprolactone/ polyethylene glycol embedded lysozyme coatings of Ti implants for osteoblast functional properties in tissue engineering
Applied Surface Science (Elsevier) Romania, 19 November 2016
Immunology
Key words: MAPLE, Dip coating, Lysozyme, Blends, Antimicrobial, Biocompatible [more]
Organism: Human
Cell Line: Primary osteogenic sarcoma cells (SAOS2), Human mesenchymal stem cells (hMSCs)
Rhinophototherapy in persistent allergic rhinitis
European Archives of Oto-Rhino-Laryngology (Springer) Hungary, 18 November 2016
Allergy Research
Key words: Intercellular adhesion molecule-1 expression, Intranasal phototherapy, Mucociliary clearance, Nasal inspiratory peak flow, Persistent allergic rhinitis, Rhinolight [more]
Organism: Human
Tissue: Mucosa
Pathological State: Allergy
The plasma membrane Ca2+ pump PMCA4b inhibits the migratory and metastatic activity of BRAF mutant melanoma cells
International Journal of Cancer (Wiley) Austria, 17 November 2016
Oncology
Key words: Ca2+, PMCA4b expression, NRAS mutant melanoma cells [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Intracerebral transplantation of interleukin 13-producing mesenchymal stem cells limits microgliosis, oligodendrocyte loss and demyelination in the cuprizone mouse model
Journal of Neuroinflammation (Springer) Belgium, 09 November 2016
Neuroscience
Key words: Interleukin 13, Mesenchymal stem cells, Neuroinflammation, Transplantation, Magnetic resonance imaging [more]
Organism: Mouse
Tissue: Brain
Pathological State: Demyelination
Dysregulation of Rab37-Mediated Cross-talk between Cancer Cells and Endothelial Cells via Thrombospondin-1 Promotes Tumor Neovasculature and Metastasis
Clinical Cancer Research (AACR Publications) Taiwan, 07 November 2016
Oncology
Key words: Rab37-Mediated, Thrombospondin-1, angiogenesis marker CD31, p-FAK/p-paxillin/p-ERK [more]
Organism: Human
Tissue: Esophagus
Pathological State: Cancer
Asxl2−/− Mice Exhibit De Novo Cardiomyocyte Production during Adulthood
Journal of Developmental Biology (MDPI) USA, 03 November 2016
Reproductive Medicine
Key words: heart, cardiogenic, cardiomyocyte, proliferation, regeneration, chromatin factor, epigenetic [more]
Organism: Mouse
Cell Line: Cardiomyocytes
A Single Postnatal Dose of Dexamethasone Enhances Memory of Rat Pups Later in Life
PLoS One (PLOS) Taiwan, 31 October 2016
Neuroscience
Key words: Postnatal dexamethasone (Dex) therapy, NMDAR, bronchopulmonary dysplasia, chronic lung disease [more]
Organism: Rat
Tissue: Brain
Cell Line Macroarray: An Alternative High-Throughput Platform to Analyze hiPSC Lines
Journal of Histochemistry & Cytochemistry (SAGE Journals) Italy, Austria, 26 October 2016
Biological Methods
Key words: cell line macroarray, high-throughput screening and quantification, hiPSC clones [more]
Organism: Human
Cell Line: hiPSCs
An Alternative High-Throughput Platform to Analyze hiPSC Lines
Journal of Histochemistry & Cytochemistry (SAGE Journals) Italy, Austria, 26 October 2016
Biological Methods
Key words: Cell line macroarray, high-throughput screening and quantification, hiPSC clones [more]
Organism: Human
Cell Line: Induced pluripotent cells (iPSCs)
Selective targeting of CREB-binding protein/β-catenin inhibits growth of and extracellular matrix remodelling by airway smooth muscle
British Journal of Pharmacology (Wiley) USA, The Netherlands, 25 October 2016
Pharmacology
Key words: Asthma, β-catenin, CREB-binding protein (CBP), TGFβ1 [more]
Organism: Mouse
Tissue: Lung
KLF6 Suppresses Metastasis of Clear Cell Renal Cell Carcinoma via Transcriptional Repression of E2F1
Molecular Cancer Research (AACR Publications) China, 25 October 2016
Oncology
Key words: KLF6 expression, E2F1-mediated epithelial–mesenchymal, cell renal cell carcinoma (ccRCC) [more]
Organism: Mouse
Tissue: Lung
Pathological State: Cancer
TRPV1 attenuates intracranial arteriole remodeling through inhibiting VSMC phenotypic modulation in hypertension
Histochemistry and Cell Biology (Springer) China, 24 October 2016
Cardiology
Key words: TRPV1, Intracranial arteriole, VSMC, Phenotypic modulation, Hypertension [more]
Organism: Mouse, Rat
Tissue: Blood Vessels, Brain
PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer
Nature Medicine (Nature) UK, 24 October 2016
Oncology
Key words: Triple-negative breast cancers (TNBCs), PIM1 proto-oncogene, anti-apoptotic factor BCL2, dynamic BH3 [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Oncolytic influenza A virus expressing interleukin-15 decreases tumor growth in vivo
Surgery (Elsevier) Austria, 21 October 2016
Immunology
Key words: Interleukin-15, A virus, T cells, [more]
Organism: Mouse
Tissue: Allograft Tumor
Pathological State: Cancer
The fractionation of adipose tissue procedure to obtain stromal vascular fractions for regenerative purposes
Wound Repair and Regeneration (Wiley) The Netherlands, 21 October 2016
Regenerative Medicine
Key words: Autologous adipose tissue transplantation, FAT-stromal vascular fraction [more]
Organism: Human
Cell Line: Smooth muscle cells (SMCs)
Distinct Differences on Neointima Formation in Immunodeficient and Humanized Mice after Carotid or Femoral Arterial Injury
Scientific Reports (Nature) USA, The Netherlands, 19 October 2016
Cardiology
Key words: NOD.Cg-PrkdcscidIL2rgtm1Wjl(NSG), Percutaneous coronary interventions (PCIs), BL/6 mice [more]
Organism: Human
Cell Line: Peripheral blood mononuclear cell
In Situ Characterization of Tissue-Resident Immune Cells by MALDI Mass Spectrometry Imaging
Journal of Proteome Research (ACS Publications) Austria, 18 October 2016
Immunology
Key words: Colon tissue, immune cells, immunohistochemistry, lymphocytes, macrophages, MALDI mass spectrometry imaging, monocytes [more]
Organism: Human
Tissue: Colon
Aberrant expression of tumor-associated carbohydrate antigen Globo H in thyroid carcinoma
Journal of Surgical Oncology (Wiley) Taiwan, 18 October 2016
Oncology
Key words: Globo H - hexasaccharide glycosphingolipid, Normal or benign thyroid, papillary thyroid cancer [more]
Organism: Human
Tissue: Thyroid
Pathological State: Cancer
Oncostatin M‐preconditioned mesenchymal stem cells alleviate bleomycin‐induced pulmonary fibrosis through paracrine effects of the hepatocyte growth factor
Stem Cells Translational Medicine (Wiley) Taiwan, Malaysia, 18 October 2016
Stem Cell Research
Key words: Bleomycin-induced pulmonary fibrosis, Hepatocyte growth factor, Oncostatin M, Preconditioning, Stem cells [more]
Organism: Mouse
Tissue: Lung
Pathological State: Pulmonary Fibrosis
Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation
Cell Death & Disease (Nature) Austria, UK, Germany, 13 October 2016
Oncology
Key words: Apoptosis, Bone cancer, Cell signalling, Sarcoma [more]
Organism: Mouse
Tissue: Whole Organism
Ustekinumab treatment in severe atopic dermatitis: Down-regulation of T-helper 2/22 expression
Journal of the American Academy of Dermatology (Elsevier) Austria, 13 October 2016
Dermatology
Key words: Anti-interleukin-12/-23 p40, atopic dermatitis, cytokines, eczema, inflammatory, T helper 2, T helper 17, T helper 22, ustekinumab [more]
Organism: Human
Tissue: Skin
Pathological State: Dermatitis
Intraarticular overexpression of Smad7 ameliorates experimental arthritis
Scientific Reports (Nature) Taiwan, 12 October 2016
Immunology
Key words: Genetic vectors, Translational immunology [more]
Organism: Human
Tissue: Bone, Connective Tissue
Hydroxyapatite thin films grown by pulsed laser deposition and matrix assisted pulsed laser evaporation: Comparative study
Applied Surface Science (Elsevier) Romania, 11 October 2016
Regenerative Medicine
Key words: Pulsed laser deposition, Matrix assisted pulsed laser evaporation, Hydroxyapatite coatings, Biocompatibility, Cell proliferation and differentiation [more]
Organism: Human
Cell Line: Human mesenchymal stem cells (hMSCs)
G-CSF-mobilized Bone Marrow Mesenchymal Stem Cells Replenish Neural Lineages in Alzheimer's Disease Mice via CXCR4/SDF-1 Chemotaxis
Molecular Neurobiology (Springer) Taiwan, 05 October 2016
Neuroscience
Key words: G-CSF, Bone marrow stem cells, SDF-1CXCR4, Neurogenesis, Alzheimer's disease [more]
Organism: Mouse
Tissue: Brain
Pathological State: Alzheimer's Disease
Neuronal prolyl-4-hydroxylase 2 deficiency improves cognitive abilities in a murine model of cerebral hypoperfusion
Experimental Neurology (Elsevier) Germany, 05 October 2016
Neuroscience
Key words: HIF, PHD, Epo, VEGF, Hippocampus, Learning, Memory, Alzheimer's disease [more]
Organism: Mouse
Tissue: Brain
Pathological State: Cerebral Hypoperfusion
Epithelial cholesterol deficiency attenuates human antigen R-linked pro-inflammatory stimulation via SREBP2-linked circuit
Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) South Korea, 04 October 2016
Gastroenterology
Key words: cholesterol regulation, inflammation, intestinal epithelium, intestinal metabolism, intestine, mRNA decay [more]
Organism: Mouse, Human
Tissue: Colon
Pathological State: Colitis
Houttuynia cordata Thunb Promotes Activation of HIF-1A–FOXO3 and MEF2A Pathways to Induce Apoptosis in Human HepG2 Hepatocellular Carcinoma Cells
Integrative Cancer Therapies (SAGE Journals) South Korea, 03 October 2016
Oncology
Key words: Cancer, cell apoptosis, hypoxia-inducible factor (HIF)-1A [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Hyperglycemia induces bioenergetic changes in adipose-derived stromal cells while their pericytic function is retained
Stem Cells and Development (Mary Ann Liebert Inc.) The Netherlands, Chile, 01 October 2016
Stem Cell Research
Key words: Adipose Derived Stromal Cells, Diabetic Retinopathy, Pericyte, Hyperglycemia [more]
Organism: Human
Cell Line: Adipose tissue derived stromal cells (ADSC)
NSAID-activated gene 1 mediates pro-inflammatory signaling activation and paclitaxel chemoresistance in type I human epithelial ovarian cancer stem-like cells
Histochemistry and Cell Biology (NCBI) South Korea, 30 September 2016
Oncology
Key words: NAG-1, epithelial ovary cancer, paclitaxel, NF-κB, chemoresistance [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
Interleukin-13 immune gene therapy prevents CNS inflammation and demyelination via alternative activation of microglia and macrophages
GLIA (Wiley) Belgium, 29 September 2016
Neuroscience
Key words: IL-13, microglia, macrophages, severe oligodendrocyte loss and demyelination, mouse nodel [more]
Organism: Mouse
Tissue: Brain
Pathological State: Demyelination
Comparison of cancer cells cultured in 2D vs 3D reveals differences in AKT/mTOR/S6-kinase signaling and drug response
Journal of Cell Science (The Company of Biologists) Austria, 23 September 2016
Oncology
Key words: Cancer cells, colon cancer, AKT/mTOR/S6-kinase, ERK phosphorylation [more]
Organism: Human
Cell Line: LS174T, HT29, SW620, HCT116), Caco2 and DLD1 (Human colon cancer cell lines)
Targeted multimodal nano-reporters for pre-procedural MRI and intra-operative image-guidance
Biomaterials (Elsevier) USA, 19 September 2016
Medical Imaging
Key words: Upconversion nanoparticles, Medical imaging, Cancer, Interventional radiology, Multimodal probe [more]
Organism: Rat
Tissue: Heart, Liver, Spleen, Lung, Kidney
CD103+ intraepithelial T cells in high-grade serous ovarian cancer are phenotypically diverse TCRαβ+ CD8αβ+ T cells that can be targeted for cancer immunotherapy
Oncotarget (Impact Journals) The Netherlands, 16 September 2016
Oncology
Key words: tumor-infiltrating lymphocytes, high-grade serous ovarian cancer, CD103, TGF-β, cancer immunotherapy [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
Expression and prognostic impact of immune modulatory molecule PD-L1 in meningioma
Journal of Neuro-Oncology (Springer) USA, 13 September 2016
Neuroscience
Key words: Meningioma, PD-L1, B7-H1, Immunotherapy, Checkpoint, Lymphocyte, Macrophage [more]
Organism: Human
Tissue: Brain
Pathological State: Cancer
Paricalcitol attenuates cardiac fibrosis and expression of endothelial cell transition markers in isoproterenol-induced cardiomyopathic rats
Critical Care Medicine (Ingentaconnect) Taiwan, 09 September 2016
Cardiology
Key words: cardiac fibrosis, cardiomyopathy, endothelial-to-mesenchymal cell transition, vitamin D activator [more]
Organism: Rat
Tissue: Heart
Pathological State: Cardiac Fibrosis
The effects of oral and topical corticosteroid in rabbit corneas
BMC Ophthalmology (BioMed Central) Japan, 05 September 2016
Ophthalmology
Key words: Corticosteroid, Keratitis, Cornea, Wound healing, Pharmacokinetics [more]
Organism: Rabbit
Tissue: Eye
Pathological State: Skin Wound
Presentation of underglycosylated mucin 1 in pancreatic adenocarcinoma (PDAC) at early stages
American Journal of Cancer Research (NCBI) USA, 01 September 2016
Oncology
Key words: Pancreatic cancer, underglycosylated mucin 1, tumor antigen, immunohistochemistry [more]
Organism: Human
Tissue: Pancreas
Pathological State: Cancer
Neural stem cells secrete factors facilitating brain regeneration upon constitutive Raf-Erk activation
Scientific Reports (Nature) South Korea, 24 August 2016
Neuroscience
Key words: Neurology, neural stem cells, Raf-Erk pathway, radial glial cells [more]
Organism: Mouse
Tissue: Brain
Degradation of Kidney and Psoas Muscle Proteins as Indicators of Post-Mortem Interval in a Rat Model, with Use of Lateral Flow Technology
PLoS One (PLOS) South Korea, 23 August 2016
Forensic Science
Key words: Post-mortem interval (PMI) markers, kidney, muscle, GAPDH [more]
Organism: Rat
Tissue: Kidney, Muscle
Toward the Automated Detection and Characterization of Osteoclasts in Microscopic Images
Principles of Osteoimmunology (Springer) Austria, 19 August 2016
Medical Image Analysis
Key words: Osteoimmunology, microscopes, biological samples, automated image segmentation and analysis
LIN28A enhances the therapeutic potential of cultured neural stem cells in a Parkinson's disease model
Brain: A journal of neurology (Oxford University Press) South Korea, 18 August 2016
Neuroscience
Key words: LIN28A, neural stem cell (NSC) culture, repair capacity, Parkinson's disease [more]
Organism: Rat
Tissue: Brain
Pathological State: Parkinson's Disease
Dynamic Modulation of Microglia/Macrophage Polarization by miR-124 after Focal Cerebral Ischemia
Journal of Neuroimmune Pharmacology (Springer) Germany, 18 August 2016
Neuroscience
Key words: Stroke, Microglia/macrophage polarization, Pro-inflammatory and anti-inflammatory phenotypes, miRNA-124, Neuroinflammation [more]
Organism: Mouse
Tissue: Brain
Pathological State: Cerebral Ischemia
The antiviral alkaloid berberine reduces chikungunya virus-induced mitogen-activated protein kinase (MAPK) signaling
Journal of Virology (American Society for Microbiology) Finland, 17 August 2016
Virology
Key words: Chikungunya virus, non-toxic plant alkaloid berberine, mitogen-activated protein kinase [more]
Organism: Mouse
Tissue: Bone, Connective Tissue
Pathological State: Chikungunya virus Infection
Bradykinin promotes neuron-generating division of neural progenitor cells via ERK activation
Journal of Cell Science (The Company of Biologists) Brazil, 15 August 2016
Neuroscience
Key words: Bradykinin, neurogenesis, TIS21 (PC3/BTG2) expression [more]
Organism: Mouse
Tissue: Brain
G9a/RelB regulates self-renewal and function of colon-cancer-initiating cells by silencing Let-7b and activating the K-RAS/β-catenin pathway
Nature Cell Biology (Nature) Taiwan, 15 August 2016
Oncology
Key words: Colorectal cancer, cancer-initiating cells phenotypes, K-RAS/β-catenin pathway [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Prevention of Colitis and Colitis-Associated Colorectal Cancer by a Novel Polypharmacological Histone Deacetylase Inhibitor
Clinical Cancer Research (AACR Publications) Taiwan, 14 August 2016
Oncology
Key words: Colorectal cancer, colitis, HDAC, HMGR [more]
Organism: Mouse
Tissue: Colon
Pathological State: Cancer
Localization of TrkB and p75 receptors in peritoneal and deep infiltrating endometriosis: an immunohistochemical study
Reproductive Biology and Endocrinology (Springer) Germany, 12 August 2016
Reproductive Medicine
Key words: Neurotrophins, BDNF, endometriosis, immunohistochemistry [more]
Organism: Human
Tissue: Endometrium
Pathological State: Endometriosis
Hypoxia-inducible factor-1α promotes glomerulosclerosis and regulates COL1A2 expression through interactions with Smad3
Kidney International (Elsevier) USA, 05 August 2016
Physiology
Key words: Fibrosis, glomerulus, hypoxia, TGF-β [more]
Organism: Mouse
Tissue: Kidney
Role of the immune system in the peritoneal tumor spread of high grade serous ovarian cancer
Oncotarget (Impact Journals) Austria, 03 August 2016
Oncology
Key words: epithelial ovarian cancer, peritoneal tumor spread, flow cytometry, PD-1, next generation sequencing [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
Sur8 mediates tumorigenesis and metastasis in colorectal cancer
Experimental & Molecular Medicine (Nature) South Korea, 29 July 2016
Oncology
Key words: Scaffold protein, Ras-extracellular signal-regulated kinase, doxycyline, HCT116 cells [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
CD271 regulates the proliferation and motility of hypopharyngeal cancer cells
Scientific Reports (Nature) Japan, 29 July 2016
Oncology
Key words: CD271 (p75 neurotrophin receptor), human hypopharyngeal cancer, head and neck squamous cell carcinoma [more]
Organism: Human
Pathological State: Cancer
Regulation of actin dynamics by WNT-5A: implications for human airway smooth muscle contraction
Scientific Reports (Nature) The Netherlands, 29 July 2016
Cell Biology
Key words: Airway hyperresponsiveness, asthm, intracellular calcium flux, actin polymerisation [more]
Organism: Human
Cell Line: Bronchial smooth muscle cells
Tissue-Resident CD169+ Macrophages Form a Crucial Front Line against Plasmodium Infection
Cell Reports (Cell Press) Singapore, 28 July 2016
Cell Biology
Key words: Plasmodium berghei ANKA, malaria, myeloid cells, macrophages [more]
Organism: Mouse
Tissue: Brain
Pathological State: Plasmodium Infection
In situ mapping of innate lymphoid cells in human skin: evidence for remarkable differences between normal and inflamed skin
Journal of Investigative Dermatology (Elsevier) Austria, Switzerland, Romania, 22 July 2016
Dermatology
Key words: Lymphoid Cells, Human Skin, Inflamed Skin, atopic dermatitis, psoriasis [more]
Organism: Human
Tissue: Skin
Pathological State: Dermatitis, Psoriasis
4 – Proffered Paper: Immunological changes during tumor progression from primary to recurrent glioblastoma
European Journal of Cancer (Elsevier) , 14 July 2016
Oncology
Key words: Cancer, tumor, glioblastoma [more]
Organism: Human
Tissue: Brain
Pathological State: Cancer
Multimodal Imaging of Nanocomposite Microspheres for Transcatheter Intra-Arterial Drug Delivery to Liver Tumors
Scientific Reports (Nature) USA, 13 July 2016
Oncology
Key words: Biomedical materials, cancer imaging, hepatic artery, nanotechnology in cancer, targeted therapies [more]
Organism: Rat
Tissue: Xenograft Tumor, Liver
Pathological State: Cancer
Quantitative comparison and reproducibility of pathologist scoring and digital image analysis of estrogen receptor β2 immunohistochemistry in prostate cancer
Diagnostic Pathology (BioMed Central) USA, 11 July 2016
Pathology
Key words: Prostate cancer, Biomarkers, Digital pathology, Quantification, Estrogen receptor β2 [more]
Organism: Human
Tissue: Prostate
Pathological State: Cancer
Induction of Suppressor Cells and Increased Tumor Growth following Chronic Psychosocial Stress in Male Mice
PLoS One (PLOS) Germany, 08 July 2016
Neuroscience
Key words: Chronic subordinate colony, myeloid cells, hypothalamus-pituitary-adrenal, sympathetic nervous system [more]
Organism: Mouse
Tissue: Spleen, Allograft Tumor
Pathological State: Cancer
Lesional CD4+ IFN-γ+ cytotoxic T lymphocytes in IgG4-related dacryoadenitis and sialoadenitis
Annals of the Rheumatic Diseases (BMJ Journals) Japan, 29 June 2016
Rheumatology
Key words: IgG4-related disease, T lymphocytes, Sjögren's syndrome, [more]
Organism: Human
Tissue: Salivary Gland
Pathological State: Cancer
Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma
OncoImmunology (Taylor and Francis) Singapore, 21 June 2016
Oncology
Key words: Metabolism, macrophages, pancreatic cancer, metastasis [more]
Organism: Human
Pathological State: Cancer
Cell Line: HPAF-II (Pancreatic epithelial tumor cell line)
ICAM-1 Binding Rhinoviruses A89 and B14 Uncoat in Different Endosomal Compartments
Journal of Virology (American Society for Microbiology) Austria, 20 June 2016
Virology
Key words: Human rhinovirus A89 (HRV-A89) and HRV-B14, RNA genome, endocytic recycling compartment (ERC) [more]
Organism: Human
Pathological State: Cancer
Cell Line: HeLA cells
Validation of tumor protein marker quantification by two independent automated immunofluorescence image analysis platforms
Modern Pathology (Nature) USA, 17 June 2016
Medical Image Analysis
Key words: Histology, biomarkers, breast tumor
Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells
Nature Communications (Nature) Taiwan, 16 June 2016
Oncology
Key words: Biological sciences, cancer, cell biology [more]
Organism: Human, Mouse
Tissue: Colon, Xenograft Tumor
Pathological State: Cancer
A new fluorescence/PET probe for targeting intracellular human telomerase reverse transcriptase (hTERT) using Tat peptide-conjugated IgM
Biochemical and Biophysical Research Communications (Elsevier) South Korea, 15 June 2016
Biological Methods
Key words: Intracellular and intranuclear protein, hTERT, tat peptide, IgM antibody, 64Cu, Live cell imaging [more]
Organism: Human
Pathological State: Cancer
Cell Line: HT29, U2OS cells
Ribosome inactivation leads to attenuation of intestinal polymeric Ig receptor expression via differential regulation of human antigen R
The Journal of Immunology (American Association of Immunologists) South Korea, 15 June 2016
Immunology
Key words: Ribosome, Polymeric Ig Receptor, Differential Regulation, Human Antigen R [more]
Organism: Mouse
Tissue: Small Intestine, Colon
Development of a novel mouse model of hepatocellular carcinoma with nonalcoholic steatohepatitis using a high-fat, choline-deficient diet and intraperitoneal injection of diethylnitrosamine
BMC Gastroenterology (BioMed Central) Japan, 13 June 2016
Oncology
Key words: Nonalcoholic steatohepatitis, hepatocellular carcinoma, diethylnitrosamine, high-fat choline-deficient diet, mouse model [more]
Organism: Mouse
Tissue: Liver
Pathological State: Hepatic Steatosis, Cancer, Liver Fibrosis