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Customer Publications (A total of 1950 papers published)

High resolution MRI for non-invasive mouse lymph node mapping

Zhuoli Zhang , Daniel Procissi, Weiguo Li, Dong-Hyun Kim, Kangan Li, Guohong Han, Yi Huan, Andrew C. Larson

Journal of Immunological Methods (Elsevier) USA, China, 11 July 2013


Key words: Mouse, Lymph node, Lymphatic drainage, India ink, Magnetic resonance imaging

Organism: Mouse

Tissue: Lymphoid Tissue

A phase I trial of aminolevulinic acid-photodynamic therapy for treatment of oral leukoplakia

Stuart J. Wong, Bruce Campbell, Becky Massey, Denis P. Lynch, Ezra E.W. Cohen, Elizabeth Blair, Rebecca Selle, Julia Shklovskaya, Borko D. Jovanovic, Silvia Skripkauskas, Alexander Dew, Peter Kulesza, Vamsi Parimi, Raymond C. Bergan, e, Eva Szabo

Oral Oncology (Elsevier) USA, 08 July 2013


Key words: Leukoplakia, aminolevulinic acid, photodynamic therapy, phase I, laser

Organism: Human

Tissue: Mucosa

Pathological State: Oral Leukoplakia

Vascular Injury Involves the Overoxidation of Peroxiredoxin Type II and Is Recovered by the Peroxiredoxin Activity Mimetic That Induces Reendothelialization

Dong Hoon Kang, Doo Jae Lee, Jiran Kim, Joo Young Lee, Hyun-Woo Kim, Kihwan Kwon, W. Robert Taylor, Hanjoong Jo, Sang Won Kang

Circulation (AHA Journals) USA, South Korea, 02 July 2013


Key words: Coronary restenosis, endothelium, peroxiredoxins, reactive oxygen species, receptor protein-tyrosine kinases

Organism: Human

Tissue: Blood Vessels

Overexpression of Lon contributes to survival and aggressive phenotype of cancer cells through mitochondrial complex I-mediated generation of reactive oxygen species

CW Cheng, CY Kuo, CC Fan, WC Fang, SS Jiang, YK Lo, TY Wang, MC Kao, AYL Lee

Cell Death & Disease (Nature) Taiwan, 20 June 2013


Key words: Apoptosis, Cancer metabolism, Pathogenesis

Organism: Human

Tissue: Mucosa

Pathological State: Cancer

THU0094 Treatment with BGP-15, a Novel Insulin Sensitizer Attenuates Collagen-Induced Arthritis in DBA/1 Mice

P. Mandl, S. Hayer, S. Blüml, V. Saferding, D. Sykoutri, C. Antus, A. Szabo, J. Smolen, K. Redlich

Annals of the Rheumatic Diseases (BMJ Journals) Austria, Hungary, 15 June 2013


Key words: Arthritis

HPV16 activates the AIM2 inflammasome in keratinocytes

M. Reinholz, Y. Kawakami, S. Salzer, A. Kreuter, Y. Dombrowski, S. Koglin, S. Kresse, T. Ruzicka, J. Schauber

Archives of Dermatological Research (Springer) Germany, 14 June 2013


Key words: Hpv16 dna, aim2 inflammasome, cytosolic dna sensor, inflammasome activation, anal intraepithelial neoplasium, hpv dna, hpv infection, il-1 release, amphotericin, caspase-1 activation, cutaneous wart, il-1 secretion, gentamicin, viral dna, hpv16 18

Organism: Human

Tissue: Skin

Pathological State: HPV Infection

Glia, Poster. Cell proliferation, lineages and differentation

C. Fenger, M. Thomassen, B. Emery, T. Kuhlmann, T.A. Kruse, B. Finsen

GLIA (Wiley) Denmark, Austria, Australia, 14 June 2013


Key words: Cell proliferation, lineages, differentiation

A practical approach to immunotherapy of hepatocellular carcinoma using T cells redirected against hepatitis B virus

S Koh, N Shimasaki, R Suwanarusk, ZZ Ho, A Chia, N Banu, S Wu Howland, AS Meoy Ong, AJ Gehring, H Stauss, L Renia, M Sällberg, D Campana, A Bertoletti

Molecular Therapy-Nucleic Acids (Cell Press) Singapore, Sweden, USA, UK, 12 June 2013

Immunology, Virology

Key words: hepatitis B virus, hepatocellular carcinoma, mRNA electroporation, TCR gene therapy

Organism: Mouse

Tissue: Spleen

Pathological State: Cancer

In vivo bioluminescence reporter gene imaging for the activation of neuronal differentiation induced by the neuronal activator neurogenin 1 (Ngn1) in neuronal precursor cells

Hyun Jeong Oh, Do Won Hwang, Hyewon Youn, Dong Soo Lee

European Journal of Nuclear Medicine and Molecular Imaging (Springer) South Korea, 11 June 2013


Key words: Reporter gene imaging, vector complex, neuronal differentiation, neuronal marker map2, gaussia luciferase, stem cell therapy, human nsc, pluripotent stem cell, grafted stem cell, neural precursor cell, hela cell, neurite outgrowth, nucleic acid delivery, nude mouse, luciferase signal

SYK Inhibition Modulates Distinct PI3K/AKT- Dependent Survival Pathways and Cholesterol Biosynthesis in Diffuse Large B Cell Lymphomas

Linfeng Chen, Stefano Monti ,Przemyslaw Juszczynski, Jing Ouyang, Bjoern Chapuy, Donna Neuberg, John G. Doench, Agata M. Bogusz,Thomas M. Habermann, Ahmet Dogan, Thomas E. Witzig, Jeffery L. Kutok, Scott J. Rodig, Todd Golub, Margaret A. Shipp

Cancer Cell (Cell Press) USA, 10 June 2013


Key words: B cell receptor, diffuse large B cell lymphoma

Histone acetyl transferase 1 is essential for mammalian development, genome stability, and the processing of newly synthesized histones H3 and H4

Prabakaran Nagarajan, Zhongqi Ge, Bianca Sirbu, Cheryl Doughty, Paula A. Agudelo Garcia, Michaela Schlederer, Anthony T. Annunziato, David Cortez, Lukas Kenner, Mark R. Parthun

PLoS Genetics (PLOS) USA, Austria, 06 June 2013


Key words: Histones , Acetylation , Chromatin , Lysine , DNA damage , Mouse models , DNA replication , Neonates

Clinical significance and evolution of hepatic HBsAg expression in HBeAg-positive patients receiving interferon therapy

Tung-Hung Su, Chun-Jen Liu, Hung-Chih Yang, Yung-Ming Jeng, Huei-Ru Cheng, Chen-Hua Liu, Tai-Chung Tseng, Thai-Yen Ling, Pei-Jer Chen, Ding-Shinn Chen, Jia-Horng Kao

Journal of Gastroenterology (Springer) Taiwan, 05 June 2013


Key words: Hbsag decline, hbsag expression, on-treatment hbsag, hbsag titer, hbsag clearance, serum hbsag, hbeag loss, hbeag-negative chb, hbv genotype, hbv dna, serum hbv-dna, hbeag-positive chb, hbsag quantification, architect hbsag, viral load

Quantitative Evaluation of Stem Cell Grafting in the Central Nervous System of Mice by In Vivo Bioluminescence Imaging and Postmortem Multicolor Histological Analysis

Kristien Reekmans, Nathalie De Vocht, Jelle Praet, Debbie Le Blon, Chloé Hoornaert, Jasmijn Daans, Annemie Van der Linden, Zwi Berneman, Peter Ponsaerts

Imaging and Tracking Stem Cells (Springer) Belgium, 04 June 2013

Stem Cell Research

Key words: Neural stem cells, mesenchymal stromal cells eGFP, luciferase, cell transplantation, brain, bioluminescence imaging, histology, microglia, astrocytes

Enhanced inhibition of prostate tumor growth by dual targeting the androgen receptor and the regulatory subunit type iα of protein kinase a in vivo

Iris E. Eder, Martina Egger , Hannes Neuwirt , Christof Seifarth , Danilo Maddalo , Andreas Desiniotis, Georg Schäfer, Martin Puhr, Jasmin Bektic, Andrew C. B. Cato and Helmut Klocker

International Journal of Molecular Sciences (MDPI) Austria, Germany, 04 June 2013


Key words: androgen receptor, cAMP-dependent protein kinase A, regulatory subunit type Iα, prostate cancer, antisense molecules, dual targeting, LNCaP xenografts, castration resistance

Smooth muscle cell transplantation improves bladder contractile function in streptozocin-induced diabetic rats

Chaitanya Gopinath, Peter Ponsaerts, Erik Fransen, Nele Boeykens, Patrick Pauwels, Jean-Jacques Wyndaele

Cytotherapy (Elsevier) Belgium, 01 June 2013

Transplantation Medicine

Key words: Bladder smooth muscle cells, cell graft survival, cell transplantation, contractile function, diabetes, in vivo cystometry

Biocompatible fluorescent nanoparticles for in vivo stem cell tracking

Lidia Cova, Paolo Bigini, Valentina Diana, Leopoldo Sitia, Raffaele Ferrari, Ruggiero Maria Pesce, Rushd Khalaf, Patrizia Bossolasco, Paolo Ubezio, Monica Lupi, Massimo Tortarolo, Laura Colombo, Daniela Giardino, Vincenzo Silani, Massimo Morbidelli, Mario Salmona and Davide Moscatelli

Nanotechnology (IOP Science) Italy, Switzerland, 20 May 2013


Key words: fluorescent nanoparticles, in vivo stem cell tracking, hAFCs, methyl methacrylate (MMA)

Increased Cdc7 expression is a marker of oral squamous cell carcinoma and overexpression of Cdc7 contributes to the resistance to DNA-damaging agents

An Ning Cheng, Shih Sheng Jiang,Chi-Chen Fan, Yu-Kang Lo, Chan-Yen Kuo, Chung-Hsing Chen, Ying-Lan Liu, Chun-Chung Lee, Wei-Shone Chen, Tze-Sing Huang, Tao-Yeuan Wang, Alan Yueh-Luen Lee

Cancer Letters (Elsevier) Taiwan, 16 May 2013


Key words: Cdc7, oral cancer, prognostic marker, chemotherapy resistance

Identification and Characterization of Poorly Differentiated Invasive Carcinomas in a Mouse Model of Pancreatic Neuroendocrine Tumorigenesis

Karen E. Hunter, Marsha L. Quick, Anguraj Sadanandam,Douglas Hanahan, Johanna A. Joyce

PLoS One (PLOS) USA, Switzerland, 14 May 2013


Key words: Insulin, differentiated tumors, invasive tumors, cell staining, insulinoma, immunofluorescence staining, carcinomas, cell differentiation

Determination of tumor-infiltrating CD8+ lymphocytes in human ovarian cancer

Aust S, Bachmayr-Heyda A, Pils D, Zhao L, Tong W, Berger A, Fogel M, Thalhammer T, Sehouli J, Horvat R, Zeillinger R, Castillo-Tong DC

International Journal of gynecological pathology (Wolters Kluwer) Austria, 10 May 2013


Key words: Tumor-infiltrating immune cells, ovarian cancer, CD8+ lymphocytes

Gaseous Hydrogen Sulfide Protects against Myocardial Ischemia-Reperfusion Injury in Mice Partially Independent from Hypometabolism

Pauline M. Snijdr , Rudolf A. de Boer, Eelke M. Bos, Joost C. van den Born, Willem-Peter T. Ruifrok, Inge Vreeswijk-Baudoin, Marcory C. R. F. van Dijk, Jan-Luuk Hillebrands,Henri G. D. Leuvenink, Harry van Goor

PLoS One (PLOS) The Netherlands, 10 May 2013


Key words: Reperfusion, necrosis, blood pressure, fibrosis, heart rate, granulocytes, heart , oxygen

Heparanase promotes lymphangiogenesis and tumor invasion in pancreatic neuroendocrine tumors

KE Hunter, C Palermo, JC Kester, K Simpson, JP Li, LH Tang, DS Klimstra, I Vlodavsky and JA Joyce

Oncogene (Nature) USA, Sweden, Israel, 06 May 2013


Key words: Lymphangiogenesis, Oncogenesis, Pancreatic cancer

Selected Abstracts from the World Conference on Interventional Oncology (WCIO) 2013

Journal of Vascular and Interventional Radiology (Elsevier) , 01 May 2013


Sex differences in IRF5 levels and implications for pDC IFN{alpha} response (P1365)

Morgane Griesbeck, Phillip Tomezsko, Erin Doyle, Michael Sirignano,Thomas Diefenbach, Marcus Altfeld, Judy Chang

The Journal of Immunology (American Association of Immunologists) USA, 01 May 2013


Key words: IRF5, Sex differences, pDC IFNα, HIV-1

Nuclear Localization of CD26 Induced by a Humanized Monoclonal Antibody Inhibits Tumor Cell Growth by Modulating of POLR2A Transcription

Kohji Yamada, Mutsumi Hayashi, Hiroko Madokoro, Hiroko Nishida, Wenlin Du, Kei Ohnuma, Michiie Sakamoto, Chikao Morimoto, Taketo Yamada

PLoS One (PLOS) Japan, 29 April 2013


Key words: Cancer treatment, mesothelioma, endocytosis, nuclear membrane, small interfering RNAs, immunoprecipitation, immunoblot analysis, cell membranes

Fluorescence endoscopy of cathepsin activity discriminates dysplasia from colitis

E Gounaris, J Martin, Y Ishihara, MW Khan, G lee, P Sinh, EZ Chen, M Angarone, R Weissleder, K Khazaie, TA Barrett

Inflammatory bowel Disease (Oxford University Press) USA, 15 April 2013


Key words: dysplasia, colitis, macrophages, cathepsin activity, fluorescence endoscopy

Intra-voxel incoherent motion MRI in rodent model of diethylnitrosamine-induced liver fibrosis

Yue Zhang, Ning Jin, Jie Deng, Yang Guo, Sarah B. White, Guang-Yu Yang, Reed A. Omary, Andrew C. Larson

Magnetic Resonance Imaging (Elsevier) USA, 15 April 2013

Medical Imaging

Key words: Intra-Voxel Incoherent Motion, Diffusion weighted MRI, Liver fibrosis

Non-Cell-Autonomous Tumor Suppression by p53

Amaia Lujambio, Leila Akkari, Janelle Simon, Danielle Grace, Darjus F. Tschaharganeh, Jessica E. Bolden, Zhen Zhao, Vishal Thapar, Johanna A. Joyce, Valery Krizhanovsky, Scott W. Lowe

CELL (Cell Press) USA, Israel, 11 April 2013


Key words: p53 tumor suppressor, hepatic stellate cells, hepatocellular carcinoma, premalignant cells

Oncogenic RAS pathway activation promotes resistance to anti-VEGF therapy through G-CSF–induced neutrophil recruitment

Vernon T. Phan, Xiumin Wu, Jason H. Cheng, Rebecca X. Sheng, Alicia S. Chung, Guanglei Zhuang, Christopher Tran, Qinghua Song, Marcin Kowanetz, Amy Sambrone, Martha Tan, Y. Gloria Meng, Erica L. Jackson, Franklin V. Peale, Melissa R. Junttila, Napoleone Ferrara

PNAS (PNAS) USA, 09 April 2013


Key words: Agiogenesis microenvironment tyrosine kinase

Increased copy-number and not DNA hypomethylation causes overexpression of the candidate proto-oncogene CYP24A1 in colorectal cancer

Julia Höbaus, Doris M. Hummel, Ursula Thiem, Irfete S. Fetahu, Abhishek Aggarwal, Leonhard Müllauer, Gerwin Heller, Gerda Egger, Ildiko Mesteri, Sabina Baumgartner-Parzer, Enikö Kallay

International Journal of Cancer (Wiley) Austria, 05 April 2013


Key words: CYP24A1, colorectal cancer, 20q13.2, methylation, proliferation

Transcatheter delivery of sorafenib-eluting polylactide-co-glycolide microspheres: therapy response studies in a rat model of hepatocellular carcinoma

J. Chen, A. Sheu, R.J. Lewandowski, R.A. Omary, L. Shea, A.C. Larson

Journal of Vascular and Interventional Radiology (Elsevier) USA, 02 April 2013


Key words: Sorafenib, hepatocellular carcinoma, polylactide-co-glycolide

Excisional Wound Healing Is Delayed in a Murine Model of Chronic Kidney Disease

Akhil K. Seth, Mauricio De la Garza, Robert C. Fang, Seok J. Hong, Robert D. Galiano

PLoS One (PLOS) USA, 25 March 2013


Key words: Chronic kidney disease, wound healing, kidneys, granulation tissue, angiogenesis, inflammation, renal failure, surgical and invasive medical procedures

Effects of Cholic Acid and its Derivatives in Experimental Arthritis

Silvia Hayer, Emina Halilbasic, Birgit Niederreiter, Martin Willburger, Peter Mandl, Victoria Saferding, Stephan Blüml, Josef Smolen, Michael Trauner, Kurt Redlich

Annals of the Rheumatic Diseases (BMJ Journals) Austria, 20 March 2013


Key words: Cholesterol metabolism, Collagen-induced arthritis, nor-ursodeoxycholic acid

Do High Molecular Weight Adiponectin Levels Associate with Radiographic Progression in early Rheumatoid Arthritis and Hand Osteoarthritis?

IR Klein-Wieringa, SN Andersen, JC Kwekkeboom, L Herb-v.Toorn, AHM van der Helm-van Mil, I Meulenbelt, TWJ Huizinga, M Kloppenburg, REM Toes, A Ioan-Facsinay

Annals of the Rheumatic Diseases (BMJ Journals) The Netherlands, 20 March 2013


Key words: Adipokines, osteoarthritis, rheumatoid arthritis

The prognostic value of estrogen receptor beta and proline-, glutamic acid- and leucine-rich protein 1 (PELP1) expression in ovarian cancer

Stefanie Aust, Peter Horak, Dietmar Pils, Sophie Pils, Christoph Grimm, Reinhard Horvat, Dan Tong, Bernd Schmid, Paul Speiser, Alexander Reinthaller, Stephan Polterauer

BMC Cancer (Springer) Austria, 14 March 2013


Key words: Mucinous ovarian cancer, residual tumor load, mucinous eoc, eoc tissue, serous eoc, clear cell carcinoma, endometrioid tumor, breast cancer tissue, cytoreductive surgery, human eoc, endometrial cancer, serum ca-125, paraaortic lymphadenectomy, undifferentiated carcinoma, surgical staging

PI3K/AKT Signaling Is Essential for Communication between Tissue-Infiltrating Mast Cells, Macrophages, and Epithelial Cells in Colitis-Induced Cancer

Mohammad W. Khan, Ali Keshavarzian, Elias Gounaris, Joshua E. Melson, Eric C. Cheon, Nichole R. Blatner, Zongmin E. Chen, Fu-Nien Tsai, Goo Lee, Hyunji Ryu, Terrence A. Barrett, David J. Bentrem, Philipp Beckhove, Khashayarsha Khazaie

Clinical Cancer Research (AACR Publications) USA, Germany, 13 March 2013


Key words: Colitis, dysplasia, colorectal cancer, colonic submucosa, phosphoinositide 3-kinase

Tumor STAT1 Transcription Factor Activity Enhances Breast Tumor Growth and Immune Suppression Mediated by Myeloid-derived Suppressor Cells

Laura M. Hix, John Karavitis, Mohammad W. Khan, Yihui H. Shi, Khashayarsha Khazaie, Ming Zhang

Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) USA, 13 March 2013


Key words: Breast Cancer, immunosuppression, signal transduction, T Cell, tumor immunology, MDSC, STAT1, mouse model of breast cancer

Type III Secretion of ExoU Is Critical during Early Pseudomonas aeruginosa Pneumonia

Heather A. Howell, Latania K. Logan, Alan R. Hauser

mBio (ASM) USA, 12 March 2013


Key words: Eukaryotic cells, Many Gram-negative bacteria, Pseudomonas aeruginosa

Rapid dramatic alterations to the tumor microstructure in pancreatic cancer following irreversible electroporation ablation

Zhuoli Zhang, Weiguo Li, Daniel Procissi, Patrick Tyler, Reed A Omary, Andrew C Larson

Nanomedicine (Future Medicine) USA, 12 March 2013


Key words: Immunohistochemistry apoptosis, IRE-treated tumors

Late Infusion of Cloned Marrow Fibroblasts Stimulates Endogenous Recovery from Radiation-Induced Lung Injury

Mineo Iwata, David K. Madtes, Kraig Abrams, Wayne J. E. Lamm, Robb W. Glenny, Richard A. Nash, Aravind Ramakrishnan, Beverly Torok-Storb

PLoS One (PLOS) USA, 08 March 2013

Regenerative Medicine

Key words: Dogs, pulmonary imaging, computed axial tomography, stem cells, fibroblasts, endothelial cells, pulmonary function, reverse transcriptase-polymerase chain reaction

Quantitative measurement of the androgen receptor in prepuces of boys with and without hypospadias

Renate Pichler, Gabriel Djedovic, Helmut Klocker, Isabel Heidegger, Alexander Strasak, Wolfgang Loidl, Jasmin Bektic, Viktor Skradski, Wolfgang Horninger, Josef Oswald

BJU International (Wiley) Austria, 07 March 2013


Key words: Hypospadias, aetiology, androgen receptor, genetics, signalling

FRI0270 Development of systemic lupus-like disease in regulatory T cells (TREG)-deficient scurfy mice

G. Stummvoll, X. Wei, H. Leiss, B. Niederreiter, B. Heckmann, W. Ulrich, A. Enk, J. Smolen, E. Hadaschik

Annals of the Rheumatic Diseases (BMJ Journals) Austria, Germany, 01 March 2013


Key words: Lupus, T cells

The 10th International Congress on SLE

McMahon M, Skaggs B, Grossman J, Sahakian L, FitzGerald J, Lourenco E, Ragavendra N, Charles-Schoeman C, Gorn A, Karpuzas G, Taylor M, Watson K, Weisman M, Wallace D, Hahn BH

Lupus (SAGE Journals) USA, 01 March 2013


Key words: Pro-inflammatory HDL, subclinical atherosclerosis, NGAL (lipocalin-2)

Hyaluronan enhances bone marrow cell therapy for myocardial repair after infarction

CH Chen, SS Wang, EIH Wei, TY Chu, PCH Hsieh

Molecular Therapy (Cell Press) Taiwan, 01 March 2013


Human Umbilical Vein Endothelial Cells Protect Against Hypoxic-Ischemic Damage in Neonatal Brain via Stromal Cell-derived Factor 1/C-X-C Chemokine Receptor Type 4

Chia-Ching Wu, Yi-Chi Chen, Ying-Chao Chang, Lan-Wan Wang, Yung-Chieh Lin, Yi-Lun Chiang, Chien-Jung Ho, Chao-Ching Huang

Stroke (AHA Journals) Taiwan, 28 February 2013


Key words: Human umbilical vein endothelial cell, neonatal brain, neurovascular unit, SDF-1/CXCR4

Noninvasive and Targeted Gene Delivery into the Brain Using Microbubble-Facilitated Focused Ultrasound

Po-Hung Hsu, Kuo-Chen Wei, Chiung-Yin Huang, Chih-Jen Wen, Tzu-Chen Yen, Chao-Lin Liu, Ya-Tin Lin, Jin-Chung Chen, Chia-Rui Shen, Hao-Li Liu

PLoS One (PLOS) Taiwan, 27 February 2013


Key words: Viral vectors, magnetic resonance imaging , central nervous system, astrocytes, gene delivery, gene expression, acoustics, neurons

Abatacept (CTLA-4IG) treatment reduces the migratory capacity of monocytes in patients with rheumatoid arthritis

M. Bonelli, E. Ferner, L. Göschl, S. Blüml, A. Hladik, T. Karonitsch, H. P. Kiener, R. Byrne, B. Niederreiter, C. W. Steiner, E. Rath, M. Bergmann, J. S. Smolen, C. Scheinecker

Arthritis & Rheumatology (Wiley) Austria, 25 February 2013


Key words: Antigen-presenting cells, CTLA-4Ig, Peripheral blood mononuclear cells

Tumor necrosis factor–inhibiting therapy preferentially targets bone destruction but not synovial inflammation in a tumor necrosis factor–driven model of rheumatoid arthritis

Nikolaus B. Binder, Antonia Puchner, Birgit Niederreiter, Silvia Hayer, Harald Leiss, Stephan Blüml, Roman Kreindl, Josef S. Smolen, Kurt Redlich

Arthritis & Rheumatology (Wiley) Austria, USA, 25 February 2013


Key words: Tumor necrosis factor, osteoclastogenesis in vitro, cell–derived monocytes

Adipose stromal cells primed with hypoxia and inflammation enhance cardiomyocyte proliferation rate in vitro through STAT3 and Erk1/2

Ewa Przybyt, Guido Krenning, Marja GL Brinker, Martin C Harmsen

Journal of Translational Medicine (Springer) The Netherlands, 13 February 2013


Key words: hl-1 cardiomyocyte, hl-1 cell, jak stat inhibitor, cardiomyocyte proliferation, cardiomyocyte proliferation, cardiomyocyte proliferation, cardiomyocyte proliferation, cardiomyocyte proliferation, cardiomyocyte proliferation, cardiomyocyte proliferation, cardiomyocyte proliferation, cardiomyocyte proliferation

Automated REcognition of Tissue-associated Erythrocytes (ARETE)—a new tool in tissue cytometry

Andreas Heindl, Alexander K. Seewald, Theresia Thalhammer, Giovanna Bises, Martin Schepelmann, Hana Uhrova, Sabine Dekan, Ildiko Mesteri, Radu Rogojanu, Isabella Ellinger

Cytometry Part A (Wiley) Austria, 11 February 2013

Medical Image Analysis

Key words: Erythrocytes, immunofluorescence microscopy, autofluorescence, tissue cytometry, automated image analysis, boosted decision trees of Haar-like features, machine learning, placenta, colorectal cancer

Characterization of Transcriptional Changes in ERG Rearrangement-Positive Prostate Cancer Identifies the Regulation of Metabolic Sensors Such as Neuropeptide Y

Petra Massoner, Karl G. Kugler, Karin Unterberger, Ruprecht Kuner, Laurin A. J. Mueller, Maria Fälth, Georg Schäfer, Christof Seifarth, Simone Ecker,Irmgard Verdorfer, Armin Graber, Holger Sültmann, Helmut Klocker

PLoS One (PLOS) Austria, Germany, 04 February 2013


Key words: Prostate cancer, gene expression, meta-analysis, prostate gland, gene regulation, microarrays, cell metabolism, glucose metabolism

Circulating Metastasis Promoting Protein S100A4 in Idiopathic Inflammatory Myopathies

L Pleštilová, O Pecha, H Mann, LA Cerezo, J Vencovský, L Šenolt

Annals of the Rheumatic Diseases (BMJ Journals) Czech Republic, 02 February 2013


Key words: Protein S100A4, rheumatoid arthritis, psoriasis

Oestrogens improve human pancreatic islet transplantation in a mouse model of insulin deficient diabetes

S. Liu, G. Kilic, M. S. Meyers, G. Navarro, Y. Wang, J. Oberholzer, F. Mauvais-Jarvis

Diabetologia (Springer) USA, China, 01 February 2013


Key words: Ffunctional vessel density, human alpha cell, human islet graft, beta cell regeneration, beta cell apoptosis, islet transplantation, islet yield, sirolimus, islet engraftment, apoptotic beta cell, cultured human islet, beta cell proliferation, tacrolimus, mouse islet, insulin independence

Long course hyperbaric oxygen stimulates neurogenesis and attenuates inflammation after ischemic stroke

YS Lee, CC Chio, CP Chang, LC Wang, PM Chiang, KC Niu, KJ Tsai

Mediators of Inflammation (Hindawi Publishing Corporation) Taiwan, 15 January 2013


Cystathionine γ-Lyase Protects against Renal Ischemia/Reperfusion by Modulating Oxidative Stress

Eelke M. Bos, Rui Wang, Pauline M. Snijder, Miriam Boersema, Jeffrey Damman, Ming Fu, Jill Moser, Jan-Luuk Hillebrands, Rutger J. Ploeg, Guangdong Yang, Henri G.D. Leuvenin, Harry van Goor

Journal of The American Society of Nephrology (JASN) Canada, UK, The Netherlands, 02 January 2013


Key words: Cystathionine γ-lyase, tubulointerstitium, glomeruli, renal ischemia

Tumor-specific expression of organic anion-transporting polypeptides: transporters as novel targets for cancer therapy

Veronika Buxhofer-Ausch, Lena Secky, Katrin Wlcek, Martin Svoboda, Valentinos Kounnis, Evangelos Briasoulis, Andreas G. Tzakos, Walter Jaeger, and Theresia Thalhammer

Journal of drug delivery (Hindawi Publishing Corporation) Austria, Switzerland, Greece, 01 January 2013


The role of glucocorticoid receptors in dexamethasone-induced apoptosis of neuroprogenitor cells in the hippocampus of rat pups

CI Sze, YC Lin, YJ Lin, TH Hsieh, YM Kuo, CH Lin

Mediators of Inflammation (Hindawi Publishing Corporation) Taiwan, 01 January 2013



Galeş, Cristina, Nechifor, M., Stoica, B., Stan, C. I., Zamfir, Carmen Lãcrãmioara

Romanian Journal of Functional and Clinical, Macro- and Microscopical Anatomy and of Anthropology () Romania, 01 January 2013

Reproductive Medicine

The effect of pioglitazone on non-pregnant female genital tract in experimental diabetes mellitus

C Gales, C Zamfir, B Stoica, M Nechifor

The Medical-Surgical  Journal (revmedchir) Romania, 01 January 2013

Reproductive Medicine


Tracing Conidial Fate and Measuring Host Cell Antifungal Activity Using a Reporter of Microbial Viability in the Lung

Anupam Jhingran, Katrina B. Mar, Debra K. Kumasaka, Sue E. Knoblaugh, Lisa Y. Ngo, Brahm H. Segal, Yoichiro Iwakura, Clifford A. Lowell, Jessica A. Hamerman, Xin Lin, Tobias M. Hohl

Cell Reports (Cell Press) USA, Japan, 27 December 2012


Key words: FLARE conidia, C-type lectin receptor, leukocyte-fungal cell

Comprehensive morphometric analysis of mononuclear cell infiltration during experimental renal allograft rejection

Ute Hoffmann, Tobias Bergler, Bettina Jung, Andreas Steege, Claudia Pace, Petra Rümmele, Stephan Reinhold, Bernd Krüger, Bernhard K. Krämer, Bernhard Banas

Transplant Immunology (Elsevier) Germany, 23 December 2012

Transplantation Medicine

Key words: B-cells, different analysis methods, experimental renal allograft rejection, macrophages, T-cells

Ectopic Pregnancy-Derived Human Trophoblastic Stem Cells Regenerate Dopaminergic Nigrostriatal Pathway to Treat Parkinsonian Rats

Tony Tung-Yin Lee, Cheng-Fang Tsai, Tsung-Hsun Hsieh, Jia-Jin Jason Chen, Yu-Chih Wang, Mi-Chun Kao, Ruey-Meei Wu, Sher Singh, Eing-Mei Tsai, Jau-Nan Lee

PLoS One (PLOS) Taiwan, 21 December 2012

Stem Cell Research

Key words: Neurons, pluripotency, flow cytometry, pregnancy, dopamine, dopaminergics, rats, cell differentiation

Enhancement of the Immunogenicity and Protective Efficacy of a Mucosal Influenza Subunit Vaccine by the Saponin Adjuvant GPI-0100

Heng Liu, Harshad P. Patil, Jacqueline de Vries-Idema, Jan Wilschut, Anke Huckriede

PLoS One (PLOS) The Netherlands, 17 December 2012


Key words: Vaccines, immunologic adjuvants, influenza, immune response, antibodies, antibody response, influenza viruses, viral vaccines

Spatiotemporal evolution of early innate immune responses triggered by neural stem cell grafting

Kristien Reekmans, Nathalie De Vocht, Jelle Praet, Erik Fransen, Debbie Le Blon, Chloé Hoornaert, Jasmijn Daans, Herman Goossens, Annemie Van der Linden, Zwi Berneman, Peter Ponsaerts

Stem Cell Research and Therapy (Springer) Belgium, 14 December 2012

Stem Cell Research

Key words: Anti-APC (Adenomatous polyposis coli protein) antibody, central nervous system, enhanced green fluorescent protein, neuronal nuclei

CHC promotes tumor growth and angiogenesis through regulation of HIF-1α and VEGF signaling

Kuo-Hua Tung, Cheng-Wei Lin, Chun-Chen Kuo, Li-Tzu Li, Ya-Hsun Kuo, Chung-Wu Lin, Han-Chung Wu

Cancer Letters (Elsevier) Taiwan, 07 December 2012


Key words: Pancreatic cancer, monoclonal antibody, clathrin heavy chain, HIF-1a, angiogenesis

Depletion of tristetraprolin in breast cancer cells increases interleukin-16 expression and promotes tumor infiltration with monocytes/macrophages

Larissa Milke, Kathrin Schulz, Andreas Weigert, Weixiao Sha, Tobias Schmid, Bernhard Brüne

Carcinogenesis (Oxford University Press) Germany, 04 December 2012


Key words: RNA-binding protein tristetraprolin, macrophages, interleukin-16, granulocyte macrophage-colony

Stem Cell-Like Differentiation Potentials of Endometrial Side Population Cells as Revealed by a Newly Developed In Vivo Endometrial Stem Cell Assay

Kaoru Miyazaki, Tetsuo Maruyama , Hirotaka Masuda, Akiko Yamasaki, Sayaka Uchida, Hideyuki Oda, Hiroshi Uchida, Yasunori Yoshimura

PLoS One (PLOS) Japan, 04 December 2012

Stem Cell Research

Key words: Stem cells, cell differentiation, kidneys, stem cell transplantation, endometrium, flow cytometry, stem cell niche, renal transplantation

Towards the Automated Detection and Characterization of Osteoclasts in Microscopic Images

Andreas Heindl, Martin Schepelmann, Rupert Ecker, Peter Pietschmann, Isabella Ellinger, Alexander K. Seewald, Theresia Thalhammer

Principles of Osteoimmunology (Springer) Austria, 01 December 2012

Medical Image Analysis

Key words: Giant Cell Tumor, Joint Photographic Expert Group, Portable Network Graphic, Biological Expert, Osteoclast Culture

Crypts detection in microscopic images using hierarchical structures

Cristian Smochina, Vasile Manta, Walter Kropatsch

Pattern Recognition Letters (Elsevier) Romania, Austria, 29 November 2012


Key words: Crypt segmentation, morphological hierarchy, morphological pyramid, biomedical imaging, pathology, microscopy

The in Vivo Imaging Platform for Cell Tracking in the Stem Cell-Induced Immune Tolerance to Vascularized Composite Allotransplantation: 1756

CJ Wen, HY Cheng, LY Shih, CF Lin, FC Wei

Transplantation (Wolters Kluwer) China, 27 November 2012


Proteinuria triggers renal lymphangiogenesis prior to the development of interstitial fibrosis

Saleh Yazdani , Fariba Poosti, Andrea B. Kramer, Katarina Mirković, Arjan J. Kwakernaak, Menno Hovingh, Maartje C. J. Slagman, Klaas A. Sjollema, Martin H. de Borst, Gerjan Navis, Harry van Goor, Jacob van den Born

PLoS One (PLOS) The Netherlands, 26 November 2012


Key words: Lymph , Proteinuria , Kidneys , Fibrosis , Macrophages , Fibroblasts , Epithelial cells , Collagens

Epithelial Cell Adhesion Molecule Regulates Tumor Initiation and Tumorigenesis via Activating Reprogramming Factors and Epithelial-Mesenchymal Transition Gene Expression in Colon Cancer

Cheng-Wei Lin, Mei-Yin Liao, Wen-Wei Lin, Yi-Ping Wang, Tung-Yin Lu, Han-Chung Wu

Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) Taiwan, 16 November 2012


Key words: Cancer Biology, Cancer Stem Cells, Cancer Tumor, Promoter Oncogene, Stem Cells EpCAM, Epithelial-Mesenchymal Transition, Reprogramming Factor Tumor-initiating, Cells Tumorsphere

Photodynamic Control of Bioactivity in a Nanofiber Matrix

Shantanu Sur, John B. Matson, Matthew J. Webber, Christina J. Newcomb, Samuel I. Stupp

ACS NANO (ACS Publications) USA, 15 November 2012


Key words: Supramolecular nanofibers, cell morphological analysis, nitrobenzyl, projected cell area, photodegradable, RGDS epitope

Valproic Acid Induces Cutaneous Wound Healing In Vivo and Enhances Keratinocyte Motility

Soung-Hoon Lee, Muhammad Zahoor, Jae-Kwan Hwang, Do Sik Min, Kang-Yell Choi

PLoS One (PLOS) South Korea, 07 November 2012


Key words: Wound healing, keratinocytes, collagens, keratins, ERK signaling cascade, Wnt signaling cascade, immunohistochemical analysis, beta-catenin signaling

SOCS-3 is downregulated in progressive CKD patients and regulates proliferation in human renal proximal tubule cells in a STAT1/3 independent manner

H Neuwirt, IE Eder, M Puhr, M Rudnicki

Laboratory Investigation (Nature) Austria, 29 October 2012


Key words: Cell proliferation, Cell signalling, Chronic kidney disease

Modulation of STAT-3 in rheumatoid synovial T cells suppresses Th17 differentiation and increases the proportion of Treg cells

Ji Hyeon Ju, Yu-Jung Heo, Mi-La Cho, Joo-Yeon Jhun, Jin-Sil Park, Seon-Yeong Lee, Hye-Jwa Oh, Su-Jin Moon, Seung-Ki Kwok, Kyung-Su Park, Sung-Hwan Park, Ho-Youn Kim

Arthritis & Rheumatology (Wiley) South Korea, 27 October 2012


Key words: STAT-3–mediated regulation, rheumatoid arthritis, CD4+ T cells, synovial fluid

Bone regeneration with low dose BMP-2 amplified by biomimetic supramolecular nanofibers within collagen scaffolds

Sungsoo S. Lee, Brian J. Huang, Stuart R. Kaltz, Shantanu Sur, Christina J. Newcomb, Stuart R. Stock, Ramille N. Shah, Samuel I. Stupp

Biomaterials (Elsevier) USA, 22 October 2012

Regenerative Medicine

Key words: Peptide amphiphile, heparin, heparan sulfate, BMP-2 (bone morphogenetic protein-2), regenerative medicine, bone regeneration

Establishing an allergic eczema model employing recombinant house dust mite allergens Der p 1 and Der p 2 in BALB/c mice

Krisztina Szalai, Tamara Kopp, Anna Lukschal, Caroline Stremnitzer, Julia Wallmann, Philipp Starkl, Luc Vander Elst, Jean-Marie Saint-Remy, Isabella Pali-Schöll, Erika Jensen-Jarolim

Experimental Dermatology (Wiley) Austria, Belgium, 15 October 2012


Key words: Allergic eczema, atopic eczema, Der p1 and Der p 2, house dust mite, protease activity, recombinant allergens

PDGFR blockade is a rational and effective therapy for NPM-ALK–driven lymphomas

Daniela Laimer, Helmut Dolznig, Karoline Kollmann, Paul W Vesely, Michaela Schlederer, Olaf Merkel, Ana-Iris Schiefer, Melanie R Hassler, Susi Heider, Lena Amenitsch, Christiane Thallinger, Philipp B Staber, Ingrid Simonitsch-Klupp, Matthias Artaker, Sabine Lagger, Suzanne D Turner, Stefano Pileri, Pier Paolo Piccaluga, Peter Valent, Katia Messana, Indira Landra, Thomas Weichhart, Sylvia Knapp, Medhat Shehata, Maria Todaro, Veronika Sexl, Gerald Höfler, Roberto Piva, Enzo Medico, Bruce A Ruggeri, Mangeng Cheng, Robert Eferl, Gerda Egger, Josef M Penninger, Ulrich Jaeger, Richard Moriggl, Giorgio Inghirami and Lukas Kenner

Nature Medicine (Nature) Austria, USA, UK, Italy, 14 October 2012


Key words: Mechanism of action, Non-hodgkin lymphoma, Therapeutics

Prospero Homeobox 1 Promotes Epithelial–Mesenchymal Transition in Colon Cancer Cells by Inhibiting E-cadherin via miR-9

Mei-Hsuan Lu, Chao-Cheng Huang, Mei-Ren Pan, Hong-Hwa Chen, Wen-Chun Hung

Clinical Cancer Research (AACR Publications) Taiwan, 08 October 2012


Key words: Prospero homeobox 1, matrix metalloproteinase activity, epithelial–mesenchymal transition

Investigation of the Relationship Between Prostate Cancer and MSMB and NCOA4 Genetic Variants and Protein Expression

Liesel M. FitzGerald, Xiaotun Zhang, Suzanne Kolb, Erika M. Kwon, Ying Ching Liew, Antonio Hurtado-Coll, Beatrice S. Knudsen, Elaine A. Ostrander, Janet L. Stanford

Human Mutation (Wiley) USA, Canada, 04 October 2012


Key words: Prostate cancer, MSMB, PSP94, NCOA4

Hepatology AASLD Abstracts

Hepatology (Wiley) UK, 01 October 2012


γ-secretase inhibitors prevent overgrowth of transplanted neural progenitors derived from human-induced pluripotent stem cells

A Ogura, A Morizane, Y Nakajima, S Miyamoto, and J Takahashi

Stem Cells and Development (Mary Ann Liebert Inc.) Japan, 28 September 2012

Regenerative Medicine

Brief Report: Amelioration of collagen-induced arthritis in mice by lentivirus-mediated silencing of microRNA-223

Yuan-Tsung Li, Shih-Yao Chen, Chrong-Reen Wang, Ming-Fei Liu, Chi-Chen Lin, I-Ming Jou, Ai-Li Shiau, Chao-Liang Wu

Arthritis & Rheumatology (Wiley) Taiwan, 27 September 2012


Key words: MicroRNA, MiRNA-223 , rheumatoid arthritis, osteoarthritis, reverse transcriptase–polymerase chain reaction

A global downregulation of microRNAs occurs in human quiescent satellite cells during myogenesis

Merel Koning, Paul M.N. Werker, Marja J.A. van Luyn, Guido Krenning, Martin C. Harmsen

Differentiation (Elsevier) The Netherlands, 26 September 2012

Developmental Biology

Key words: Satellite cells, Skeletal muscle, Quiescence, MicroRNA, MicroRNA microarray

Male Microchimerism in the Human Female Brain

William F. N. Chan , Cécile Gurnot, Thomas J. Montine, Joshua A. Sonnen, Katherine A. Guthrie, J. Lee Nelson

PLoS One (PLOS) USA, 26 September 2012


Key words: Alzheimer disease, brain diseases, pregnancy, natural history of disease, amygdala, frontal lobe, washington, Y chromosomes

Improved assessment of frozen/thawed mouse spermatozoa using fluorescence microscopy

AK Diercks, HF Bürgers, A Schwab, J Schenkel

Journal of veterinary science (Kamje Press) Germany, 20 September 2012

Reproductive Medicine

Key words: cryopreservation, fluorescence microscopy, genetically modified (GM) mice, membrane integrity, 3Rs

Comparative Secretome Analyses Using a Hollow Fiber Culture System with Label-Free Quantitative Proteomics Indicates the Influence of PARK7 on Cell Proliferation and Migration/Invasion in Lung Adenocarcinoma

Ying-Hua Chang , Shu-Hui Lee, Hua-Chien Chang, Yau-Lin Tseng, Wu-Wei La, Chen-Chung Lia, Yeou-Guang Tsa, and Pao-Chi Liao

Journal of Proteome Research (ACS Publications) Taiwan, 17 September 2012


Key words: Hollow fiber culture system, label-free quantitative proteomics, PARK7, cancer metastasis

Honey bee (Apis mellifera) venom induces AIM2 inflammasome activation in human keratinocytes

Y. Dombrowski, M. Peric, S. Koglin, N. Kaymakanov, V. Schmezer, M. Reinholz, T. Ruzicka andJ. Schauber

Allergy (Wiley) Germany, 13 September 2012

Allergy Research

Key words: AIM2 inflammasome, allergic reaction, cytosolic DNA, honey bee venom, keratinocytes

Prevention of preneoplastic lesions by dietary vitamin D in a mouse model of colorectal carcinogenesis

Doris Maria Hummel, Ursula Thiem, Julia Höbaus, Ildiko Mesteri, Lukas Gober, Caroline Stremnitzer, João Graça, Barbara Obermayer-Pietsch, Enikö Kallay

The Journal of Steroid Biochemistry and Molecular Biology (Elsevier) Austria, UK, 11 September 2012


Key words: Vitamin D, colorectal cancer, dysplasia, chemoprevention, cyp24a1, cyp27b1

Quantitative Immunofluorescence Reveals the Signature of Active B-cell Receptor Signaling in Diffuse Large B-cell Lymphoma

Agata M. Bogusz, Richard H.G. Baxter, Treeve Currie, Papiya Sinha, Aliyah R. Sohani, Jeffery L. Kutok, Scott J. Rodig

Clinical Cancer Research (AACR Publications) USA, 10 September 2012


Key words: B-cell receptor, diffuse large B-cell lymphomas, DLBCL pathogenesis

Isolation and phenotypic characterisation of stem cells from late stage osteoarthritic mesenchymal tissues

Labusca, Luminita, Zugun-Eloae, Florin, Shaw, Georgina, Botez, Paul, Barry, Frank, Mashayekhi, Kaveh

Current stem cell research and Therapy (Ingentaconnect) Romania, 01 September 2012

Stem Cell Research

Key words: Chondrogenesis, mesenchymal stem cells, osteoarthritis, regenerative medicine.

The use of a tumor metastasis targeting peptide to deliver doxorubicin-containing liposomes to highly metastatic cancer

Zhaohui Wang, Yang Yu, Wenbing Dai, Jingkai Lu, Jingrong Cui, Hounan Wu, Lan Yuan, Hua Zhang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Qiang Zhang

Biomaterials (Elsevier) China, 30 August 2012


Key words: Highly metastatic tumor, targeting, nanomedicine, liposomes, delivery

Neuron-Specific Prolyl-4-Hydroxylase Domain 2 Knockout Reduces Brain Injury After Transient Cerebral Ischemia

NS Prolyl, H Domain

Stroke (AHA Journals) Germany, 28 August 2012


Key words: HIF-1  hypoxia  neuroprotection  PHD  stroke

Epithelial-to-Mesenchymal Transition Leads to Docetaxel Resistance in Prostate Cancer and Is Mediated by Reduced Expression of miR-200c and miR-205

Martin Puhr, Julia Hoefer, Georg Schäfer, Holger H.H. Erb, Su Jung Oh, Helmut Klocker, Isabel Heidegger, Hannes Neuwirt, Zoran Culig

The American Journal of Pathology (Elsevier) China, 11 August 2012


Key words: Docetaxel, (miR)-200c, miR-205, E-cadherin, Systemic polychemotherapy

Quantitative and phenotypic analysis of mesenchymal stromal cell graft survival and recognition by microglia and astrocytes in mouse brain

Nathalie De Vocht,Dan Lin, Jelle Praet, Chloé Hoornaert, Kristien Reekmans, Debbie Le Blon, Jasmijn Daans, Patrick Pauwels, Herman Goossens, Niel Hens, Zwi Berneman, Annemie Van der Linden, Peter Ponsaert

Immunobiology (Elsevier) Belgium, 09 August 2012


Key words: Astrocytes, brain, cell transplantation, mesenchymal stromal cell, microglia

A mouse model to identify cooperating signaling pathways in cancer

Monica Musteanu, Leander Blaas, Rainer Zenz, Jasmin Svinka, Thomas Hoffmann, Beatrice Grabner, Daniel Schramek, Hans-Peter Kantner, Mathias Müller, Thomas Kolbe, Thomas Rülicke, Richard Moriggl, Lukas Kenner, Dagmar Stoiber, Josef Martin Penninger, Helmut Popper, Emilio Casanova and Robert Eferl

Nature Methods (Nature) Austria, Spain, 05 August 2012


Key words: animal disease models, Cancer genetics, Mouse

Activation of Notch Signaling During Ex Vivo Expansion Maintains Donor Muscle Cell Engraftment

Maura H. Parker, Carol Loretz, Ashlee E. Tyler, William J. Duddy, John K. Hall, Bradley B. Olwin, Irwin D. Bernstein, Rainer Storb, Stephen J. Tapscott

Stem Cells (Wiley) USA, 03 August 2012

Stem Cell Research

Key words: Striated muscle, satellite cells, regeneration, primary cell culture, notch ligand, cell transplantation

Coordinated roles of ST3Gal-VI and ST3Gal-IV sialyltransferases in the synthesis of selectin ligands

Won Ho Yang, Claudia Nussbaum, Prabhjit K. Grewal, Jamey D. Marth, Markus Sperandio

Blood (American Society of Hematology) USA, Germany, 02 August 2012


Key words: Leukocyte trafficking, ST3Gal subfamily, protein glycosylation

Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43

I-Fang Wang, Bo-Shen Guo, Yu-Chih Liu, Cheng-Chun Wu, Chun-Hung Yang, Kuen-Jer Che-Kun James Shen

PNAS (PNAS) USA, 02 August 2012


Key words: Protein aggregation, neuronal apoptosis

Chapter 9 - Correlated Light Microscopy and Electron Microscopy

Klaas A. Sjollema, Ulrike Schnell, Jeroen Kuipers, Ruby Kalicharan, Ben N.G. Giepmans

Methods in Cell Biology (Elsevier) The Netherlands, 31 July 2012


Key words: Light microscopy, electron microscopy, correlated microscopy, orientation, probes, high resolution, drawing tube, mosaic microscopy

Abstracts for the International Federation of Placenta Associations Meeting 2012

Placenta (Elsevier) , 25 July 2012

Reproductive Medicine

Vasohibin-2 Expressed in Human Serous Ovarian Adenocarcinoma Accelerates Tumor Growth by Promoting Angiogenesis

Yoshifumi Takahashi, Takahiro Koyanagi, Yasuhiro Suzuki, Yasushi Saga, Naoki Kanomata, Takuya Moriya, Mitsuaki Suzuki, Yasufumi Sato

Molecular Cancer Research (AACR Publications) Japan, 23 July 2012


Key words: Vasohibin-1, angiogenesis, ovarian cancer, Angiopoietins

The vitamin D receptor activator paricalcitol prevents fibrosis and diastolic dysfunction in a murine model of pressure overload

Laura M.G. Meems, Megan V. Cannon, Hasan Mahmud, Adriaan A. Voors, Wiek H. van Gilst, Herman H.W. Silljé, Willem P.T. Ruifrok, Rudolf A. de Boer

The Journal of Steroid Biochemistry and Molecular Biology (Elsevier) The Netherlands, 15 July 2012


Key words: Fibrosis, heart failure, paricalcitol, remodeling, vitamin D receptor, renin

1107 In Vitro Generated Human Dendritic Cells Exposed to a Potent Maturation Melanoma Cell Lines Lysate Show a Tolerogenic-like Phenotype and Functionality When Exposed to Dexamethasone Prior to the Maturation Stimuli

C. Falcon-Beas, F. Tempio, B. Pesce, J. Aguillon, C. Pereda, C. Saffie, F. Salazar-Onfray, M.N. Lopez

European Journal of Cancer (Elsevier) , 06 July 2012


1110 Modulation of Genistein- and Resveratrol-induced Apoptosis and Cell Proliferation in Colon Cancer Cells

L.I. Brasoveanu, D. Hotnog, C. Hotnog, M. Bostan, M. Mihaila

European Journal of Cancer (Elsevier) , 06 July 2012


1109 Density and Organization of B Cells, Including the Activation-induced Cytidine Deaminase (AID)-positive Sub-population, Within Active Tumor Border of Human Colorectal Cancer Liver Metastases Shows a Positive Association With Survival Prognosis

A. Meshcheryakova, M. Svoboda, E. Bajna, J. Maresch, J. Jensen-Jarolim, M. Bergmann, D. Tamandl, D. Mechtcheriakova

European Journal of Cancer (Elsevier) , 06 July 2012


1108 Histidine-rich Glycoprotein Regulates Macrophage Differentiation

O. Noguer, S. Tugues, S. Honjo, L. Claesson-Welsh

European Journal of Cancer (Elsevier) , 06 July 2012


Tumour‐secreted miR‐9 promotes endothelial cell migration and angiogenesis by activating the JAK‐STAT pathway

Guanglei Zhuang, Xiumin Wu, Zhaoshi Jiang, Ian Kasman, Jenny Yao, Yinghui Guan, Jason Oeh, Zora Modrusan, Carlos Bais, Deepak Sampath, Napoleone Ferrara

EMBO Journal (EMBO press) USA, 06 July 2012


Key words: Angiogenesis, Endothelium, JAK‐STAT, MicroRNA, Tumour

A Novel Nucleus-Based Classifier for Discrimination of Osteoclasts and Mesenchymal Precursor Cells in Mouse Bone Marrow Cultures

Andreas Heindl, Alexander K. Seewald, Martin Schepelmann, Radu Rogojanu, Giovanna Bises, Theresia Thalhammer, and Isabella Ellinger

International Journal of Medical and Health Sciences (Open Science Index) Austria, 01 July 2012


Key words: osteoclasts, machine learning, ellipse fitting.

Pristane-induced lupus as a model of human lupus arthritis: evolvement of autoantibodies, internal organ and joint inflammation

H Leiss, B Niederreiter, T Bandur, B Schwarzecker, S Blüml, G Steiner, W Ulrich3, JS Smolen, GH Stummvoll

Lupus (SAGE Journals) Austria, 01 July 2012


Key words: Lupus arthritis pristane-induced lupus (PIL), systemic lupus erythematosus (SLE)

RasGRF1 regulates proliferation and metastatic behavior of human alveolar rhabdomyosarcomas

Maciej Tarnowski, Gabriela Schneider, Gabriele Amann, Geoffrey Clark, Peter Houghton, Frederic G. Barr, Lukas Kenner, Mariusz Z. Ratajczak, Magda Kucia

International Journal of Oncology (Spandidos Publications) USA, Austria, Poland, 28 June 2012


Cisplatin and quantum dots encapsulated in liposomes as multifunctional nanocarriers for theranostic use in brain and skin

Li-Wen Zhang, Chih-Jen Wen, Saleh A. Al-Suwayeh, Tzu-Chen Yen, Jia-You Fang

Journal of Nanoparticle Research (Springer) Taiwan, Saudi Arabia, 19 June 2012


Key words: Cdse zns qds, cdse zns nanocrystal, nude mouse skin, cdse zns quantum, cisplatin release, mouse skin section, blank liposome, cdse core, skin melanoma, vesicle size, quantum dot, entrapment efficiency, skin uptake, non-treatment group, cisplatin accumulation

Monitoring neutrophils and platelets during casein-induced anaphylaxis in an experimental BALB/c mouse model

D. Krishnamurti, P. Starkl, K. Szalai, F. Roth-Walter, S. C. Diesner, M. Mittlboeck, C. Manhalter, E. Untersmayr, E. Jensen-Jarolim

Clinical and Experimental Allergy (Wiley) Austria, 15 June 2012

Allergy Research

Key words: Mast cells, basophils , alum-adsorbed casein, peripheral neutropenia

Quantitative analysis of binding sites for 9-fluoropropyl-(+)-dihydrotetrabenazine ([18F]AV-133) in a MPTP-lesioned PD mouse model

Ko-Ting Chao, Hsin-Hsin Tsao, Yi-Hsin Weng, Ing-Tsung Hsiao, Chia-Ju Hsieh, Shiaw-Pyng Wey, Tzu-Chen Yen, Mei-Ping Kung,Kun-Ju Lin

Synapse (Wiley) Taiwan, 13 June 2012


Key words: Positron emission tomography, quantitative autoradiography, immunohistochemistry, vesicular monoamine transporter 2, standardized uptake value

Prognostic role of indoleamine 2,3-dioxygenase in endometrial carcinoma

Renske A. de Jong, Ido P. Kema, Annemarie Boerma, H. Marike Boezen, Johannes J.L. van der Want, Marloes J.M. Gooden, Harry Hollema, Hans W. Nijman

Gynecologic Oncology (Elsevier) The Netherlands, 02 June 2012


Key words: Endometrial carcinoma, indoleamine 2, 3-dioxygenase, T-lymphocytes, prognosis

Evidence That Activated Hedgehog Signaling Predicts for Poor Clinical Outcome in Acute Myeloid Leukemia

Veronica Campbell, Eleni Tholouli, M. Travis Quigley, John Keilty, Patrick Kelly, Karen McGovern, Margaret Read, Jeffery L. Kutok, Richard Byers

Blood (American Society of Hematology) USA, UK, 01 June 2012


Key words: Hedgehog (Hh), Acute Myeloid Leukemia (AML), Primary CD34+ myeloid blasts

CD256 can be found in antibody-mediated renal allograft rejection tissues

Xu H, He X, Zhao W, Guo H, Shi Q, Zhu Y, Zhang X.

Clinical Laboratory (NCBI) China, 01 June 2012

Transplantation Medicine

Key words: Tumor necrosis factor, Systemic lupus erythematosus, Rheumatoid arthritis, antibody-mediated rejection

Type 2 diabetes mellitus is associated with an imbalance in circulating endothelial and smooth muscle progenitor cell numbers

J. van Ark, J. Moser, C. P. H. Lexis, F. Bekkema, I. Pop, I. C. C. van der Horst, C. J. Zeebregts, H. van Goor, B. H. R. Wolffenbuttel, J. L. Hillebrands

Diabetologia (Springer) The Netherlands, 01 June 2012


Key words: smc marker gene, smc differentiation, epc count, mature smc, angiogenic cell, fibrous cap, cell subset, smc lineage, mature ecs, vascular repair, atherosclerotic plaque, real-time rt-pcr, repair capacity, endothelial differentiation, cell mobilisation

Clinical significance of the ratio between FOXP3 positive regulatory T cell and interleukin-17 secreting cell in renal allograft biopsies with acute T-cell-mediated rejection

Byung H. Chung, Hye J. Oh, Shang G. Piao, Hyeon S. Hwang, In O. Sun, Sun R. Choi, Hoon S. Park, Bum S. Choi, Yeong J. Choi, Cheol W. Park, Yong-SoKim, Mi-La Cho Chul W. Yan

Immunology (Wiley) South Korea, 01 June 2012


Key words: Acute T-cell-mediated rejection, FOXP3, interleukin-17, regulatory T cell, T helper type 17

Point sur les avancées technologiques en hémocytométrie aux JIB 2011

F. Berge , G. Maggiore, A. Frenkian

IRBM News (Elsevier) France, 01 June 2012


Chemical shift MR imaging methods for the quantification of transcatheter lipiodol delivery to the liver: preclinical feasibility studies in a rodent model

Xiaoming Yin, Yang Guo, Weiguo Li, Eugene Huo, Zhuoli Zhang, Jodi Nicolai, Robert A. Kleps, Diego Hernando, Aggelos K. Katsaggelos, Reed A. Omary, Andrew C. Larson

Radiology (Radiological Society of North America) USA, 01 June 2012

Medical Image Analysis

96. Jahrestagung der Deutschen Gesellschaft für Pathologie e. V.

Der Pathologe (Springer) Germany, 27 May 2012


Neural precursors (NPCs) from adult L967Q mice display early commitment to “in vitro” neuronal differentiation and hyperexcitability

Francesca DiFebo, Daniela Curti, Francesca Botti, Gerardo Biella, Paolo Bigini, Tiziana Mennini, Mauro Toselli

Experimental Neurology (Elsevier) Italy, 22 May 2012


Key words: Neural stem/progenitor cells (NPCs), motoneuron, neurodegeneration, amyotrophic lateral sclerosis, wobbler mouse, sodium channel, hyperexcitability, patch-clamp

Selective CDK4/6 inhibition with tumor responses by PD0332991 in patients with mantle cell lymphoma

John P. Leonard, Ann S. LaCasce, Mitchell R. Smith, Ariela Noy, Lucian R. Chirieac, Scott J. Rodig, Jian Q. Yu, Shankar Vallabhajosula, Heiko Schoder, Patricia English, Donna S. Neuberg, Peter Martin, Michael M. Millenson, Scott A. Ely, Rachel Courtney, Naveed Shaik, Keith D. Wilner, Sophia Randolph, Annick D. Van den Abbeele, Selina Y. Chen-Kiang, Jeffrey T. Yap, Geoffrey I. Shapiro

Blood (American Society of Hematology) USA, 17 May 2012


Key words: Mantle cell lymphoma, cyclin D1–dependent kinase activity, bortezomib, temsirolimus, lenalidomide

Snapshot spectral imaging using optimized diffractive optical elements

M De Biasio, T Arnold, A Tortschanoff, A Hermerschmidt, R Leitner

Next-Generation Spectroscopic Technologies (SPIE) Austria, Germany, 17 May 2012


Key words: snapshot, CTIS, DOE, optimization

RTEL1 contributes to DNA replication and repair and telomere maintenance

Evert-Jan Uringa, Kathleen Lisaingo, Hilda A. Pickett, Julie Brind'Amour, Jan-Hendrik Rohde, Alex Zelensky, Jeroen Essers, Peter M. Lansdorp

Molecular Biology of The Cell (American Society for Cell Biology) Canada, The Netherlands, Australia, 11 May 2012

Cell Biology

Key words: Telomere maintenance, DNA, mRtel1 , embryonic stem cells

Abating colon cancer polyposis by Lactobacillus acidophilus deficient in lipoteichoic acid

Khashayarsha Khazaie, Mojgan Zadeh, Mohammad W. Khan, Praveen Bere, Fotini Gounari, Kirsten Dennis, Nichole R. Blatner, Jennifer L. Owen, Todd R. Klaenhammerd, Mansour Mohamadzadeh

PNAS (PNAS) USA, 01 May 2012


Key words: Dendritic cells regulatory, T cells anti-inflammatory

Magnesium sulfate and nimesulide have synergistic effects on rescuing brain damage after transient focal ischemia

LC Wang, CY Huang, HK Wang, MH Wu, KJ Tsai

Journal of Neurotrauma (Mary Ann Liebert Inc.) Taiwan, 25 April 2012


Key words: in vivo studies, ischemia, middle cerebral artery occlusion, therapeutic approach, stroke

Mice lacking epidermal PPARγ exhibit a marked augmentation in photocarcinogenesis associated with increased UVB-induced apoptosis, inflammation and barrier dysfunction

Ravi P. Sahu, Sonia C. DaSilva, Badri Rashid, Kellie Clay Martel, Danielle Jernigan, Shama R. Mehta, Deena R. Mohamed, Samin Rezania, Joshua R. Bradish, Andrew B. Armstrong, Simon Warren, Raymond L. Konger

International Journal of Cancer (Wiley) USA, 18 April 2012


Key words: Photocarcinogenesis, peroxisome proliferators activated receptor gamma, inflammation, apoptosis, differentiation, nonmelanoma skin cancer

Hedgehog pathway inhibitor saridegib (IPI-926) increases lifespan in a mouse medulloblastoma model

Michelle J. Lee, Beryl A. Hatton, Elisabeth H. Villavicencio, Paritosh C. Khanna, Seth D. Friedman, Sally Ditzler, Barbara Pullar, Keith Robison, Kerry F. White, Chris Tunkey, Michael LeBlanc, Julie Randolph-Habecker, Sue E. Knoblaugh, Stacey Hansen, Andrew Richards, Brandon J. Wainwright, Karen McGovern, James M. Olson

PNAS (PNAS) USA, Australia, 04 April 2012


Key words: Sonic Hedgehog (Shh) pathway, medulloblastomas, P-glycoprotein (Pgp)

Injection of Amniotic Fluid Stem Cells Delays Progression of Renal Fibrosis

Sargis Sedrakyan, Stefano Da Sacco, Anna Milanesi, Liron Shiri, Astgik Petrosyan, Radka Varimezova, David Warburton, Kevin V. Lemley, Roger E. De Filippo, Laura Perin

Journal of The American Society of Nephrology (JASN) USA, 01 April 2012


Key words: Stem cells, renal fibrosis

Antagonistic effects of selenium and lipid peroxides on growth control in early hepatocellular carcinoma

Nataliya Rohr-Udilova, Wolfgang Sieghart, Robert Eferl, Dagmar Stoiber, Linda Björkhem-Bergman, Lennart C. Eriksson, Klaus Stolze6 Hubert Hayden, Bernhard Keppler, Sandra Sagmeister, Bettina Grasl-Kraupp, Rolf Schulte-Hermann Markus Peck-Radosavljevic

Hepatology (Wiley) Austria, Sweden, 27 March 2012


Key words: Vascular endothelial growth factor, hepatocellular carcinomas, antioxidative glutathione peroxidases

Requirement of Cellular Prion Protein for Intestinal Barrier Function and Mislocalization in Patients With Inflammatory Bowel Disease

Constance S.V. Peti, Frédérick Barreau, Laura Besnie, Pierre Gandill, Béatrice Rivea, Danielle Chatea, Maryline Ro, Dominique Berreb, Magali Svrce, Philippe Cardo, Monique Rousse, Caroline Clai, Sophie Thenet

Gastroenterology (Elsevier) France, 22 March 2012


Key words: Tight Junction, mouse model, cell–cell adhesion, inflammation

Biosafety of Non-Surface Modified Carbon Nanocapsules as a Potential Alternative to Carbon Nanotubes for Drug Delivery Purposes

Alan C. L. Tang, Gan-Lin Hwang, Shih-Jung Tsai, Min-Yao Chang, Zack C. W. Tang, Meng-Da Tsai, Chwan-Yao Luo, Allan S. Hoffman, Patrick C. H. Hsieh

PLoS One (PLOS) Taiwan, USA, 22 March 2012


Key words: Carbon nanotubes, nanomaterials, drug delivery, toxicity, intravenous injections, cytokines, inflammation, alcohols

Induction of intestinal pro-inflammatory immune responses by lipoteichoic acid

Mojgan Zadeh, Mohammad W Khan, Yong Jun Goh, Kurt Selle, Jennifer L Owen, Todd Klaenhammer, Mansour Mohamadzadeh

Journal of Inflammation (Springer) USA, 16 March 2012


Key words: Dendritic cell, dextran sulfate sodium, inflammatory bowel disease, lipoteichoic acid, toll-like receptor 2

Comparative oncology: ErbB-1 and ErbB-2 homologues in canine cancer are susceptible to cetuximab and trastuzumab targeting

Josef Singer, Marlene Weichselbaumera, Thomas Stockner, Diana Mechtcheriakova, Yury Sobanov, Erika Bajna, Friedrich Wrba, Reinhard Horvat, Johann G. Thalhammer, Michael Willmann, Erika Jensen-Jarolim

Molecular Immunology (Elsevier) Austria, 16 March 2012


Key words: Comparative oncology, ErbB-1, ErbB-2, Human, Canine, Breast cancer

Involvement of the insular cortex in regulating glucocorticoid effects on memory consolidation of inhibitory avoidance training

R Fornari, R Wichmann, E Atucha, T Desprez, E Eggens-Meijer and B Roozendaal

Frontiers in behavioral neuroscience (Frontiers Media S.A.) The Netherlands, Brazil, 15 March 2012


Deficiency of the macrophage growth factor CSF-1 disrupts pancreatic neuroendocrine tumor development

SM Pyonteck, BB Gadea, HW Wang, V Gocheva, KE Hunter, LH Tang, JA Joyce

Oncogene (Nature) USA, 15 March 2012


Preserved Function of Regulatory T Cells in Chronic HIV-1 Infection Despite Decreased Numbers in Blood and Tissue

Mathieu Angin, Douglas S. Kwon, Hendrik Streeck, Fang Wen, Melanie King, Ashley Rezai, Kenneth Law, Tomoyuki C. Hongo, Augustine Pyo, Alicja Piechocka-Trocha, Ildiko Toth, Florencia Pereyra, Musie Ghebremichael, Scott J. Rodig, Danny A. Milner Jr, James M. Richter, Marcus Altfeld, Daniel E. Kaufmann, Bruce D. Walker, Marylyn M. Addo

Journal of Infectious Diseases (Oxford University Press) USA, 15 March 2012

Immunology, Virology

Key words: Regulatory T cells (Tregs), T lymphocytes, cytotoxic, lymphoid tissue (GALT)

An Essential Role for Modulation of Hyperpolarization-Activated Current in the Development of Binaural Temporal Precision

Sukant Khurana, Zhiqiang Liu, Alan S. Lewis, Kristen Rosa, Dane Chetkovich, Nace L. Golding

Journal of Neuroscience (SFN) USA, 22 February 2012


Key words: Medial superior olive , binaural neurons, hyperpolarization-activated current, cyclic nucleotide-gated (HCN) channels

Regulation of Axonal HCN1 Trafficking in Perforant Path Involves Expression of Specific TRIP8b Isoforms

Wiebke Wilkars , Zhiqiang Liu , Alan S. Lewis, Travis R. Stoub, Elena M. Ramos, Nicola Brandt, Daniel A. Nicholson, Dane M. Chetkovich, Roland A. Bender

PLoS One (PLOS) Germany, USA, 21 February 2012


Key words: Neurons, neuronal dendrites, axons, neuronal differentiation, immunohistochemistry techniques, pyramidal cells, in situ hybridization, hippocampus

Inhibition of CD26/DPP-IV enhances donor muscle cell engraftment and stimulates sustained donor cell proliferation

Maura H Parker, Carol Loretz, Ashlee E Tyler, Lauren Snider, Rainer Storb, Stephen J Tapscott

Skeletal Muscle (Springer) USA, 16 February 2012

Regenerative Medicine

Key words: Muscular dystrophy, cell transplantation, xenotransplant, canine, CXCR4, diprotin A

Combined strategies of apomorphine diester prodrugs and nanostructured lipid carriers for efficient brain targeting

Kuo-Sheng Liu, Chih-Jen Wen, Tzu-Chen Yen, K C Sung, Ming-Chuan Ku, Jhi-Joung Wang, Jia-You Fang

Nanotechnology (IOP Science) Taiwan, Saudi Arabia, 10 February 2012


Key words: nanostructured lipid carriers, diacetyl apomorphine , diisobutyryl apomorphine, DAA, DIA

Optimisation of the diffractive optical element for snapshot spectral imaging used in fluorescence microscopy

R. Leitner, T. Arnold, M. De Biasio, G. McGunnigle, R. Rogojanu, G. E. Steiner, A. Hermerschmidt

Computational Microscopy (SPIE) Austria, Germany, 09 February 2012


Key words: Luminescence, microscopy, optical components, maging spectroscopy, cameras, reconstruction algorithms, spectral resolution, spectrometers, imaging systems, computed tomography

Polycaprolactone electrospun mesh conjugated with an MSC affinity peptide for MSC homing in vivo

Zhenxing Shao, Xin Zhang, Yanbin Pi, Xiaokun Wang, Zhuqing Jia, Jingxian Zhu, Linghui Dai, Wenqing Chen, Ling Yin, Haifeng Chen, Chunyan Zhou, Yingfang Ao

Biomaterials (Elsevier) China, 07 February 2012

Biological Materials

Key words: Phage display, tssue engineering (TE), MSC-homing, peptide-modified polycaprolactone electrospun mesh

Soy Isoflavone Supplementation for Breast Cancer Risk Reduction: A Randomized Phase II Trial

Seema A. Khan, Robert T. Chatterton, Nancy Michel, Michelle Bryk, Oukseub Lee, David Ivancic, Richard Heinz, Carola M. Zalles, Irene B. Helenowski, Borko D. Jovanovic, Adrian A. Franke, Maarten C. Bosland, Jun Wang, Nora M. Hansen, Kevin P. Bethke, Alexander Dew, Margerie Coomes, Raymond C. Bergan

Cancer Prevention Research (AACR Publications) USA, 05 February 2012


Key words: breast cancer, breast epithelial proliferation, random fine-needle aspiration

Single-walled carbon nanotubes induce airway hyperreactivity and parenchymal injury in mice

WY Hsieh, CC Chou, CC Ho, SL Yu, HY Chen, HYE Chou, JJW Chen, HW Chen, PC Yang

American Journal of Respiratory Cell and Molecular Biology (ATS Journals) Taiwan, 01 February 2012


Key words: single-walled carbon nanotubes, toxicity, matrix metalloproteinase2, cathepsin K, NF-κB

Swine Leukocyte Antigen-DQ Expression and Its Regulation by Interferon-Gamma at the Maternal-Fetal Interface in Pigs

Mingoo Kim, Heewon Seo, Yohan Choi, Jangsoo Shim, Fuller W. Bazer, Hakhyun Ka

Biology of Reproduction (SSR) South Korea, 01 February 2012

Reproductive Medicine

Key words: Endometrium female reproductive tract pig pregnancy reproductive immunology SLA-DQ uterus

Modulating intestinal immune responses by lipoteichoic acid-deficient Lactobacillus acidophilus

Mohammad W Khan, Mojgan Zadeh, Praveen Bere, Elias Gounaris, Jennifer Owen, Todd Klaenhammer, Mansour Mohamadzadeh

Immunotherapy (FSG) USA, 01 February 2012


Key words: Microbe Lactobacillus acidophilus, lipoteichoic acid-deficient strain, dendritic cells and macrophages

Lamin A/C protein is overexpressed in tissue-invading prostate cancer and promotes prostate cancer cell growth, migration and invasion through the PI3K/AKT/PTEN pathway

Lu Kong, Georg Schäfer Huajie Bu, Yong Zhang, Yuxiang Zhang, Helmut Klocker

Carcinogenesis (Oxford University Press) Austria, China, 21 January 2012


Key words: cell growth, 1-phosphatidylinositol 3-kinase , cell lines, neoplasms, prostate cancer, pten gene, protein overexpression, proto-oncogene proteins c-akt, phosphoinositide 3-kinase, lamin type a

Intratumoral heterogeneity in anaplastic large cell lymphoma of non-common subtype

Dmitriy Abramov, Ilske Oschlies, Dmitriy Konovalov, Christine Damm-Welk, Wilhelm Wössmann, Wolfram Klapper

Journal of Hematopathology (Springer) Germany, Russia, 14 January 2012


Key words: Anaplastic large cell lymphoma, ALK, Digital image analysis

Tubular epithelial syndecan-1 maintains renal function in murine ischemia/reperfusion and human transplantation

Celie JW, Katta KK, Adepu S, Melenhorst WB, Reijmers RM, Slot EM, Beelen RH, Spaargaren M, Ploeg RJ, Navis G, van der Heide JJ, van Dijk MC, van Goor H, van den Born J.

Kidney international (Elsevier) The Netherlands, 11 January 2012


Key words: kidney transplantation, proliferation, renal epithelial cell, renal ischemia-reperfusion, transplant outcomes

A role for Epstein–Barr viral BALF1 in facilitating tumor formation and metastasis potential

Wen-Li Hsua, Pei-Jung Chungb, Ming-Hsien Tsaia, Cicero Lee-Tian Changc, Chih-Lung Liang

Virus research (Elsevier) Taiwan, 02 January 2012

Oncology, Virology

Key words: EBV, BALF1, Transformation, Tumor, Metastasis

Robotic Microscopy and information technology to increase accuracy, sensitivity and availability of blood cell analyses

V Medovyi, A Pyatnitskiy

Current Microscopy Contributions to Advances in Science and Technology (FORMATEX) Russia, 01 January 2012


Key words: robotic microscopy, blood smear analysis, virtual slide, laboratory telemedicine, image cytometry, virtual microscopy, image analysis, pattern recognition, artificial intelligence

Increased activation of the PI3K/AKT pathway compromises decidualization of stromal cells from endometriosis

X Yin, ME Pavone, Z Lu, JJ Wei, JJ Kim

Journal of Clinical Endocrinology and Metabolism (Oxford University Press) USA, 01 January 2012

Reproductive Medicine

Magnetization transfer MRI in pancreatic cancer xenograft models

Weiguo Li, Zhuoli Zhang, Jodi Nicolai, Guang-Yu Yang, Reed A. Omary, Andrew C. Larson

Magnetic Resonance in Medicine (Wiley) USA, 28 December 2011


Key words: Magnetization transfer, fibrosis, pancreatic cancer, mouse xenograft model

MicroRNA-1 and microRNA-206 improve differentiation potential of human satellite cells: a novel approach for tissue engineering of skeletal muscle

M Koning, PMN Werker, DWJ van der Schaft, RA Bank, MC Harmsen

Tissue Engineering Part A (Mary Ann Liebert Inc.) The Netherlands, 20 December 2011

Regenerative Medicine

Macrophages in human colorectal cancer are pro-inflammatory and prime T cells towards an anti-tumour type-1 inflammatory response

Siew-Min Ong, Yann-Chong Tan, Ottavio Beretta, Dongsheng Jiang, Wei-Hseun Yeap, June J. Y. Tai, Wing-Cheong Wong, Henry Yang, Herbert Schwarz, Kiat-Hon Lim, Poh-Koon Koh, Khoon-Lin Ling, Siew-Cheng Wong

European Journal of Immunology (Wiley) Singapore, 12 December 2011


Key words: Chemokines, cytokines, spheroid model, T-cell co-stimulation, tumour-associated macrophages (TAMs)

Sensorimotor assessment of the unilateral 6-hydroxydopamine mouse model of Parkinson's disease

KE Glajch, SM Fleming, DJ Surmeier, P Osten

Behavioural Brain Research (Elsevier) USA, 09 December 2011


Key words: Parkinson's disease, 6-OHDA, Mouse, Behavioral test, Sensorimotor impairment, Medial forebrain bundle

Digital Transplantation Pathology: Combining Whole Slide Imaging, Multiplex Staining and Automated Image Analysis

K. Isse, A. Lesniak, K. Grama, B. Roysam, M. I. Minervini A. J. Demetris

American Journal of Transplantation (Wiley) USA, 04 November 2011

Transplantation Medicine

Key words: Allograft pathology, C4d, digital image, fibrosis, quantitative analysis, quantum dots, three-dimensional imaging

Gas challenge–blood oxygen level-dependent (GC-BOLD) MRI in the rat Novikoff hepatoma model

Yang Guo, Ning Jin, Rachel Klein, Jodi Nicolai, Guang-Yu Yang, Reed A. Omary, Andrew C. Larson

Magnetic Resonance Imaging (Elsevier) USA, 04 November 2011


Key words: Gas challenge–blood oxygen level dependent (GC-BOLD), MRI, Rat Novikoff hepatoma, Tumor angiogenesis, Tumor microvessel density

Evaluation of Functional and Structural Alterations in Muscle Tissue after Short-Term Cold Storage in a New Tissue Preservation Solution

Wille T., Gonder S., Thiermann H.,Seeger T.,Rauen U., Worek F.

Cells Tissues Organs (Karger) Germany, 01 November 2011

Regenerative Medicine

Key words: Muscle tissue, preservation solution

Epithelial Area Detection in Cytokeratin Microscopic Images Using MSER Segmentation in an Anisotropic Pyramid

Cristian Smochina, Radu Rogojanu, Vasile Manta, Walter Kropatsch

Pattern Recognition in Bioinformatics (Springer) Romania, Austria, 01 November 2011

Medical Image Analysis

Key words: Crypt segmentation, Anisotropic diffusion pyramid, MSER, Biomedical imaging, Pathology, Microscopy, Fluorescence microscopy, Image analysis

Impact of interleukin-21 in the pathogenesis of primary Sjogren's syndrome: increased serum levels of interleukin-21 and its expression in the labial salivary glands

Kwi Young Kang, Hyun-Ok Kim, Seung-Ki Kwok, Ji Hyeon Ju, Kyung-Su Park, Dong-Il Sun, Joo Yeon Jhun, Hye Jwa Oh, Sung-Hwan Park, Ho-Youn Kim

Arthritis Research and Therapy (Springer) South Korea, 26 October 2011


Key words: Serum il-21, anti-ro ssa antibody, synovial membrane cell, labial salivary gland, il-21r expression, il-21 gene, anti-ro la antibody, salivary gland biopsy, tfh cell, ectopic germinal center, encephalitis, th17 cell, nkt cell, il-21 concentration, ductal cell

Regulation of Oocyte and Cumulus Cell Interactions by Intermedin/Adrenomedullin 2

Chia Lin Chang, Hsin-Shih Wang, Yung-Kuei Soong, Shang Yu Huang, Shun Yuan Pa, Sheau Yu Teddy Hsu

Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) Taiwan, USA, 18 October 2011

Reproductive Medicine

Key words: Apoptosis, Bioinformatics, Cell Compartmentation, Cyclic AMP (cAMP), G Protein-coupled Receptors (GPCR), Ovary Peptide Hormones Adrenomedullin CGRP

Sampling step importance in hierarchical semantic segmentation of microscopic images

Smochina C., Manta V., Kropatsch W.

System Theory, Control, and Computing (IEEEXplore) Romania, Austria, 16 October 2011


Key words: Semantic segmentation of microscopic images

Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer

Tanaya Shree, Oakley C. Olson, Benelita T. Elie, Jemila C. Kester, Alfred L. Garfall, Kenishana Simpson, Katherine M. Bell-McGuinn, Emily C. Zabor, Edi Brogi, Johanna A. Joyce

Genes and Development (CSH Press) USA, 12 October 2011


Key words: Cancer metastasis, chemotherapy, tumor microenvironment, proteolysis paclitaxel

Activation-Induced Cytidine Deaminase (AID)-Associated Multigene Signature to Assess Impact of AID in Etiology of Diseases with Inflammatory Component

Diana Mechtcheriakova, Yury Sobanov, Gabriele Holtappels, Erika Bajna, Martin Svoboda, Markus Jaritz, Claus Bachert, Erika Jensen-Jarolim

PLoS One (PLOS) Austria, Belgium, 03 October 2011


Key words: Immunity, inflamation

Evaluating the role of connexin43 in congenital heart disease: Screening for mutations in patients with outflow tract anomalies and the analysis of knock-in mouse …

GY Huang, LJ Xie, KL Linask, C Zhang, XQ Zhao, YI Yang, GM Zhou, YJ Wu, L Marquez-Rosado, DB McElhinney, E Goldmuntz, C Liu, PD Lampe, B Chatterjee, CW Lo

Journal of Cardiovascular Disease Research (Elsevier) USA, China, 01 October 2011


Key words: Connexin43, congenital heart disease, gap junction, knock-in mouse model, outflow tract, phosphorylations

Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice

Kristina M. Mueller, Jan-Wilhelm Kornfeld, Katrin Friedbichler, Leander Blaas, Gerda Egger, Harald Esterbauer, Peter Hasselblatt, Michaela Schlederer, Susanne Haindl, Kay-Uwe Wagner, David Engblom, Guenter Haemmerle, Dagmar Kratky, Veronika Sexl, Lukas Kenner, Andrey V. Kozlov, Luigi Terracciano, Rudolf Zechner, Guenther Schuetz, Emilio Casanova, J. Andrew Pospisilik, Markus H. Heim, Richard Moriggl

Hepatology (Wiley) Austria, Germany, USA, Sweden, Switzerland, 27 September 2011


Key words: Growth hormone (GH), peroxisome proliferator, systemic lipid homeostasis

Soluble gp130 Regulates Prostate Cancer Invasion and Progression in an Interleukin-6 Dependent and Independent Manner

Shahrokh F. Shariat, Thomas F. Chromecki, Julia Hoefer, Christopher E. Barbieri, Douglas S. Scherr, Pierre I. Karakiewicz, Claus G. Roehrborn, Francesco Montoris, Zoran Culigd, Ilaria T. Cavarretta

Journal of Urology (Elsevier) USA, Austria, Italy, Canada, 23 September 2011


Key words: Prostate, prostatic neoplasms, neoplasm invasiveness, cytokine receptor gp130, biological markers

Angiopoietin-Like 4 Regulates Epidermal Differentiation

Mintu Pal, Ming Jie Tan, Royston-Luke Huang, Yan Yih Goh, Xiao Ling Wang, Mark Boon Yang Tang, Nguan Soon Tan

PLoS One (PLOS) Singapore, 22 September 2011


Key words: Keratinocytes, cell differentiation, epidermis, immunoblotting, biopsy, DNA transcription, messenger RNA, wound healing

Semantic Segmentation of Microscopic Images Using a Morphological Hierarchy

Cristian Smochina, Vasile Manta, Walter Kropatsch

Computer Analysis of Images and Patterns (Springer) Romania, Austria, 31 August 2011

Medical Image Analysis

Key words: Crypt segmentation, Morphological hierarchy, Biomedical imaging, Pathology, Microscopy

Abstracts for the IFPA Meeting 2011

Placenta (Elsevier) Austria, 27 August 2011

Expression of the IGF Axis Is Decreased in Local Prostate Cancer but Enhanced after Benign Prostate Epithelial Differentiation and TGF-β Treatment

Petra Massoner, Michael Ladurner Rennau, Isabel Heidegger, Anita Kloss-Brandstätter, Monika Summerer, Eva Reichhart, Georg Schäfer, Helmut Klocker

The American Journal of Pathology (Elsevier) Austria, 26 August 2011


Key words: Insulin-like growth factor (IGF),

Higher infiltration by Th17 cells compared with regulatory T cells is associated with severe acute T-cell-mediated graft rejection

Byung Ha Chung, Hye Jwa Oh, Shang Guo Piao, In O Sun, Seok Hui Kang, Sun Ryoung Choi, Hoon Suk Park, Bum Soon Choi, Yeong Jin Choi, Cheol Whee Park, Yong-Soo Kim, Mi-La Cho and Chul Woo Yang

Experimental and Molecular Medicine (Nature) South Korea, 24 August 2011


Modifiers of mutant huntingtin aggregation: functional conservation of C. elegans-modifiers of polyglutamine aggregation

Eva Teuling, Annika Bourgonje, Sven Veenje, Karen Thijssen, Jelle de Boer, Joeri van der Velde, Morris Swertz, Ellen Nollen

Plos Currents (PLOS) The Netherlands, 12 August 2011


Spatiotemporal expression of SERPINE2 in the human placenta and its role in extravillous trophoblast migration and invasion

Schu-Rern Chern, Sheng-Hsiang Li, Chien-Ling Chiu, Hsiao-Ho Chang, Chih-Ping Chen, Edmund I Tsuen Chen

Reproductive Biology and Endocrinology (Springer) Taiwan, 02 August 2011

Reproductive Medicine

Key words: SERPINE2, plasminogen activator (PA) system, tissue remodeling, pregnancy, trophoblasts

Herpesvirus Entry Mediator and Nectin-1 Mediate Herpes Simplex Virus 1 Infection of the Murine Cornea

Andrew H. Karaba, Sarah J. Kopp and Richard Longnecker

Journal of Virology (American Society for Microbiology) USA, 27 July 2011


Key words: Herpes, infection

Expression of a functional VEGFR-1 in tumor cells is a major determinant of anti-PlGF antibodies efficacy

Jenny Yao, Xiumin Wu, Guanglei Zhuang, Ian M. Kasman, Tobias Vogt, Vernon Phan, Masabumi Shibuya, Napoleone Ferrara, Carlos Bais

PNAS (PNAS) Japan, Italy, 12 July 2011


Key words: Stroma tyrosine, kinase placental growth, factor vascular, endothelial growth, factor angiogenesis

Kupffer cells support extramedullary erythropoiesis induced by nitrogen-containing bisphosphonate in splenectomized mice

Hirotada Otsuka, Hideki Yagi, Yasuo Endo, Naoko Nonaka, Masanori Nakamura

Cellular Immunology (Elsevier) Japan, 05 July 2011


Key words: Nitrogen-containing bisphosphonate (NBP), Kupffer cell, Extramedullary erythropoiesis

Modeling Colon Adenocarcinomas in Vitro: A 3D Co-Culture System Induces Cancer-Relevant Pathways upon Tumor Cell and Stromal Fibroblast Interaction

Helmut Dolznig, Christian Rupp, Christina Puri, Christian Haslinger, Norbert Schweifer, Elisabeth Wieser, Dontscho Kerjaschki, Pilar Garin-Chesa

The American Journal of Pathology (Elsevier) Austria, 01 July 2011


Key words: Colon adenocarcinoma, in vitro

The Presence and Localization of Melatonin Receptors in the Rat Aorta

Martin Schepelmann, Lubos Molcan, Hana Uhrova, Michal Zeman, Isabella Ellinger

Cellular and Molecular Neurobiology (Springer) Austria, Slovakia, 22 June 2011


Key words: Mt1 receptor, saponin, arterial stiffness, melatonin concentration, rhythmic gene expression, rat eyerenal artery, clock gene bmal1, nadph oxidase, pineal gland , nocturnal hypertension

FTY720 Reduces Post-Ischemic Brain Lymphocyte Influx but Does Not Improve Outcome in Permanent Murine Cerebral Ischemia

Arthur Lie, Li Sun, Wei Zhou, Sönke Schwarting, Eva Mracsko, Markus Zorn, Henrike Bauer, Clemens Sommer, Roland Veltkamp

PLoS One (PLOS) Germany, 20 June 2011


Key words: Ischemic strok e, Cerebral ischemia, Lymphocytes, Cytokines, T cells, Granulocytes, White blood cells, Monocytes

An rhs gene of Pseudomonas aeruginosa encodes a virulence protein that activates the inflammasome

Vanderlene L. Kung, Sonal Khare, Christian Stehlik, Elizabeth M. Bacon, Ami J. Hughes, Alan R. Hauser

PNAS (PNAS) USA, 09 June 2011


Key words: Rhs element, YD repeat, pathogenesis

Spontaneous and aging-dependent development of arthritis in NADPH oxidase 2 deficiency through altered differentiation of CD11b+ and Th/Treg cells

Kihyun Lee, Hee Yeon Won, Myung Ae Bae, Jeong-Ho Hong, Eun Sook Hwang

PNAS (PNAS) South Korea, 07 June 2011


Key words: Rheumatoid arthritis myeloid-derived suppressor cell

Vasculatures in Tumors Growing From Preirradiated Tissues: Formed by Vasculogenesis and Resistant to Radiation and Antiangiogenic Therapy

Fang-Hsin Chen, Chi-Shiun Chiang, Chun-Chieh Wang, Sheng-Yung Fu, Chien-Sheng Tsai, Shih-Ming Jung, Chih-Jen Wen, Chung-Chi Lee, Ji-Hong Hong

International Journal of Radiation Oncology*Biology*Physics (Elsevier) Taiwan, 27 May 2011


Key words: Radiation, Tumor bed effects, Microvascular density, Green fluorescent protein–tagged bone marrow, Antiangiogenic therapy

Cytosolic DNA Triggers Inflammasome Activation in Keratinocytes in Psoriatic Lesions

Yvonne Dombrowski, Mark Peric, Sarah Koglin, Claudia Kammerbauer, Christine Göß, David Anz, Maren Simanski, Regine Gläser, Jürgen Harder, Veit Hornung, Richard L. Gallo, Thomas Ruzicka, Robert Beschand, Jürgen Schauber

Science Translational Medicine (American Association for the Advancement of Science) Germany, USA, 11 May 2011


Key words: Psoriasis, keratinocytes, antimicrobial cathelicidin peptide LL-37,

Influence of melatonin on murine osteoclast formation in culture — Automated detection and quantification by a novel image analysis system

M. Schepelmann, A. Heindl, A. Seewald, A. Nussbaumer, G. Bises, R. Rogojanu, P. Pietschmann, I. Ellinger, T. Thalhammer

Bone (Elsevier) Austria, 07 May 2011

Medical Image Analysis

Automated detection, quantification and characterization of osteoclasts in cultures using a combined image-processing and machine-learning strategy

A. Heindl, M. Schepelmann, R. Stumberger, A. Nussbaumer, c, P. Pietschmann, G. Bisesa, R. Rogojanu, d, T. Thalhammer, A. Seewald, I. Ellinger

Bone (Elsevier) Austria, 07 May 2011

Medical Image Analysis

Key words: Osteoclasts

The analysis of organic anion transporting polypeptide (OATP) mRNA and protein patterns in primary and metastatic liver cancer

Katrin Wlcek, Martin Svoboda, Juliane Riha, Susanna Zakaria, Ulrike Olszewski, Zdenek Dvorak, Franz Sellner, Isabella Ellinger, Walter Jäger, Theresia Thalhammer

Cancer Biology and Therapy (Taylor and Francis) Austria, 01 May 2011


Key words: Polypeptides, cholangiocellular carcinoma, hepatocellular carcinoma

Segmentation of cell nuclei within chained structures in microscopic images of colon sections

C Smochina, A Serban, V Manta

Proceedings of the 27th Spring Conference on Computer Graphics (Association for Computing Machinery) Romania, 30 April 2011

Medical Image Analysis

Key words: Image segmentation, biomedical imaging, nucleus segmentation.

Aberrant expression of CD30 in neoplastic mast cells in high-grade mastocytosis

Sotlar K, Cerny-Reiterer S, Petat-Dutter K, Hessel H, Berezowska S, Müllauer L, Valent P, Horny HP.

Modern Pathology (NCBI) Germany, 24 April 2011


Key words: Neoplastic mast cells, mastocytosis, reactive mast cell hyperplasia


C. Saitta, T. Pollicino, G. Raffa, A. Bertuccio, A. Barbera, A. Ciancio, A. Smedile, G. Navarra, G. Raimondo

Journal of Hepatology (Elsevier) Italy, 18 April 2011



A. Pelc, K. Roos, M. Meinhard, H. Mundt, B. Besenbeck, H. Schulze-Bergkamen, W. Stremmel, M. Müller

Journal of Hepatology (Elsevier) Germany, 18 April 2011



N. Rohr-Udilova, W. Sieghart, R. Eferl, M. Peck-Radosavljevic

Journal of Hepatology (Elsevier) , 18 April 2011

Transplantation Medicine


V. Salvatore, M. Baron Toaldo, S. Marinelli, C. Palamà, L. Gramantieri, M. Cipone, L. Bolondi, F. Piscaglia

Journal of Hepatology (Elsevier) Italy, 18 April 2011


Effector T-Cell Infiltration Positively Impacts Survival of Glioblastoma Patients and Is Impaired by Tumor-Derived TGF-β

Jennifer Lohr, Thomas Ratliff, Andrea Huppertz, Yingzi Ge, Christine Dictus, Rezvan Ahmadi, Stefan Grau, Nobuyoshi Hiraoka, Volker Eckstein, Rupert C. Ecker, Thomas Korff, Andreas von Deimling, Andreas Unterberg, Philipp Beckhove, Christel Herold-Mende

Clinical Cancer Research (AACR Publications) Germany, 08 April 2011


Key words: Tumor, flow citometry

Expression of organic anion-transporting polypeptides 1B3, 1B1, and 1A2 in human pancreatic cancer reveals a new class of potential therapeutic targets

Kounnis V, Ioachim E, Svoboda M, Tzakos A, Sainis I, Thalhammer T, Steiner G, Briasoulis E.

OncoTargets and Therapy (Dove Press) Greece, Austria, 08 April 2011


Key words: organic anion-transporting polypeptides, targeted therapy, transporter

Effect of Additional Boron on Tibias of African Ostrich Chicks

Jiayue Cheng, Kemei Peng, Erhui Jin, Yong Zhang, Yan Liu, Ningbo Zhang, Hui Song, Huazhen Liu, Zhonglin Tang

Biological Trace Element Research (Springer) China, 02 April 2011

Biological Materials

Key words: Ostrich chick, cortical bone thickness, bone volume fraction, boron intake, trabecular bone microarchitecture, boron addition, ovx rat, boron content, dietary boron bone strength, calcium phosphate, bone turnover, drinking water, bone mass


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