Customer Publications (A total of 2600 papers published)
Nutritional and Pharmacological Targeting of the Calcium-Sensing Receptor Influences Chemically Induced Colitis in Mice
Nutrients (MDPI) Austria, Germany, UK, 16 December 2019
Gastroenterology
Key words: IBD, Colitis, Inflammation, Calcium, Mucin [more]
Organism: Mouse
Tissue: Colon
Pathological State: Colitis
Ultrasound-mediated Delivery of Paclitaxel for Glioma: A Comparative Study of Distribution, Toxicity, and Efficacy of Albumin-bound Versus Cremophor Formulations
Clinical Cancer Research (AACR Publications) USA, Mexico, France, 12 December 2019
Oncology
Organism: Mouse
Tissue: Brain
Pathological State: Cancer
Smooth muscle cytochrome b5 reductase 3 deficiency accelerates pulmonary hypertension development in sickle cell mice
Blood Advances (ASH Publications) USA, 10 December 2019
Cardiology
Organism: Mouse
Tissue: Heart
Targeting FOXA1-mediated repression of TGF-b signaling suppresses castration-resistant prostate cancer progression
JCI Insight (American Society of Clinical Investigation) USA, 04 December 2019
Oncology
Key words: Genetics, Oncology, Prostate Cancer [more]
Organism: Human
Tissue: Prostate
Pathological State: Cancer
Molecular Pattern and Density of Axons in the Long Head of the Biceps Tendon and the Superior Labrum
Journal of Clinical Medicine (MDPI) Austria, 03 December 2019
Physiology
Key words: axons, pain, long head of the biceps tendon, superior labrum, SLAP [more]
Organism: Human
Tissue: Connective Tissue
Early appearance of key transcription factors influence the spatiotemporal development of the human inner ear
Cell and Tissue Research (Springer) Austria, Canada, Sweden, 02 December 2019
Developmental Biology
Key words: Inner ear, Human, Transcription factors, Immunohistochemistry, SOX2, TAK1, GATA3, Electron microscopy [more]
Organism: Human
Tissue: Bone
PRMT1 suppresses ATF4-mediated endoplasmic reticulum response in cardiomyocytes
Cell Death & Disease (Nature) South Korea, 02 December 2019
Cardiology
Key words: Cell death, Heart failure [more]
Organism: Mouse
Tissue: Heart
Tissue-infiltrating immune cells contribute to understanding the pathogenesis of Kimura disease: A case report
Medicine (Wolters Kluwer) Japan, USA, 01 December 2019
Immunology
Key words: CD4+ T cell, CD4+ GATA3+ T cell, IgE, Kimura disease, mast cell [more]
Organism: Human
Tissue: Lymphoid Tissue
Pathological State: Kimura Disease
Histologic Analysis of Sensory and Motor Axons in Branches of the Human Brachial Plexus
Plastic and Reconstructive Surgery (American Society of Plastic Surgeons) USA, 01 December 2019
Regenerative Medicine
Organism: Human
Tissue: Nerves
Sirtuin 5 Regulates Proximal Tubule Fatty Acid Oxidation to Protect against AKI
Journal of The American Society of Nephrology (American Society of Nephrology) USA, 29 November 2019
Nephrology
Organism: Mouse
Tissue: Kidney
Pathological State: Acute Kidney Injury
Development of Kaempferol-Loaded Gelatin Nanoparticles for the Treatment of Corneal Neovascularization in Mice
Pharmaceutics (MDPI) Taiwan, Australia, 28 November 2019
Nanomedicine
Key words: gelatin nanoparticles, kaempferol, corneal neovascularization, anti-angiogenesis, human umbilical vascular endothelial cells (HUVECs) [more]
Organism: Mouse
Tissue: Eye
DNMT3b/OCT4 expression confers sorafenib resistance and poor prognosis of hepatocellular carcinoma through IL-6/STAT3 regulation
Journal of Experimental & Clinical Cancer Research (BMC) Taiwan, 26 November 2019
Oncology
Key words: , Interleukin-6, Phospho-STAT3, OCT4, DNMT3b, Drug resistance, Hepatocellular carcinoma [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function
Immunity (Elsevier) Austria, USA, Switzerland, Germany, China, 26 November 2019
Immunology
Key words: CD8 T cells, hepatitis, hepatocyte, immunometabolism, infection, inflammation, interferons, liver, urea cycle, virus [more]
Organism: Mouse
Tissue: Liver
Pathological State: LCMV Infection
Functionally Overlapping Variants Control Tuberculosis Susceptibility in Collaborative Cross Mice
mBio (American Society for Microbiology) USA, 26 November 2019
Microbiology
Key words: Mycobacterium tuberculosis, adaptive immunity, Collaborative Cross mice, host genetics, host response, host-pathogen interactions [more]
Organism: Mouse
Tissue: Lung
Pathological State: Tuberculosis
Promising Therapeutic Efficacy of GC1118, an Anti-EGFR Antibody, against KRAS Mutation-Driven Colorectal Cancer Patient-Derived Xenografts
International Journal of Molecular Sciences (MDPI) South Korea, 24 November 2019
Oncology
Key words: colorectal cancer, patient-derived xenograft, EGFR-targeting therapeutic antibody, KRAS mutation, PI3K/mTOR/AKT inhibitor [more]
Organism: Mouse
Tissue: Colon, Xenograft Tumor
Pathological State: Cancer
Translational interest of immune profiling
Precision Medicine for Investigators, Practitioners and Providers (Elsevier) Saudi Arabia, 22 November 2019
Immunology
Key words: Biomarkers, Immunoprofiling, Multiplex Immunohistochemistry, Novel Therapies, Next Generation Sequencing, Protein Arrays, Translational Research, xMAP Assays
Influence of Platelet Lysate on 2D and 3D Amniotic Mesenchymal Stem Cell Cultures
Frontiers in Bioengineering and Biotechnology (Frontiers Media S.A.) Austria, 15 November 2019
Regenerative Medicine
Key words: mesenchymal stem cells, stress fibers, mitochondrial dynamics, platelet lysate, membrane elasticity [more]
Organism: Human
Cell Line: hMSCs
Cordycepin inhibits human ovarian cancer by inducing autophagy and apoptosis through Dickkopf-related protein 1/β-catenin signaling
American Journal of Translational Regulation (NCBI) South Korea, 15 November 2019
Oncology
Key words: Apoptosis, Dickkopf-related protein 1, β-catenin, autophagy, cordycepin [more]
Organism: Human
Pathological State: Cancer
Cell Line: SKOV-3, OVCAR-3
Endoplasmic reticulum stress-mediated basolateral amygdala GABAergic neuron injury is associated with stress-induced mental disorders in rats
Frontiers in Cellular Neuroscience (NCBI) China, Usa, Mexico, 14 November 2019
Neuroscience
Key words: stress, amygdala, GABAergic neurons, mental disorder, endoplasmic reticulum stress [more]
Organism: Rat
Tissue: Brain
Large‐scale Production of LGR5‐positive Bipotential Human Liver Stem Cells
Hepatology (AASLD) The Netherlands, Spain, Belgium, 12 November 2019
Hepathology
Key words: Liver organoids, suspension culture, spinner flask, hepatocyte differentation, tissue engineering [more]
Organism: Human
Tissue: Liver
Linear ubiquitin assembly complex regulates lung epithelial driven responses during influenza infection
The Journal of Clinical Investigation (American Society of Clinical Investigation) USA, Japan, 12 November 2019
Immunology
Organism: Mouse
Tissue: Lung
Pathological State: Influenza Infection
P2Y6 and P2X7 receptor antagonism exerts neuroprotective/neuroregenerative effects in an animal model of Parkinson's disease
Frontiers in Cellular Neuroscience (Frontiers Media S.A.) Brazil, 08 November 2019
Neuroscience
Key words: purinergic receptors, Brilliant Blue G, P2X7 receptor, MRS2578, P2Y6 receptor, Parkinson's disease, microglia [more]
Organism: Rat
Tissue: Brain
Pathological State: Parkinson's Disease
A self-assembled RNA-triple helix hydrogel drug delivery system targeting triple-negative breast cancer
Journal of Materials Chemistry B (Royal Society of Chemistry) China, 08 November 2019
Nanomedicine, Oncology
Organism: Human
Pathological State: Cancer
Cell Line: MDA-MB-231 cells, MCF-7 cells and HeLa cells
Gastroprotective effects of Kangfuxin against water-immersion and restraint stress-induced gastric ulcer in rats: roles of antioxidation, anti-inflammation, and pro-survival
Pharmaceutical Biology (Taylor & Francis) China, 07 November 2019
Gastroenterology
Key words: Periplaneta americana L., gastric diseases, IGF-1/PTEN/Akt signalling, KFX [more]
Organism: Rat
Tissue: Stomach
Pathological State: Gastric Ulcer
Osteocyte dysfunction promotes osteoarthritis through MMP13-dependent suppression of subchondral bone homeostasis
Bone research (Nature) USA, 05 November 2019
Osteology
Key words: Bone, Bone quality and biomechanics, Pathogenesis [more]
Organism: Human
Tissue: Bone
Well Plate Integrated Topography Gradient Screening Technology for Studying Cell‐Surface Topography Interactions
Advanced Biosystems (Wiley) The Netherlands, China, 04 November 2019
Biological Materials
Key words: Biointerfaces, gradients, high-throughput screening, stem cells surface topography [more]
Organism: Human
Cell Line: hBM-MSCs
Mapping of c-Fos expression in male tree shrew forebrain
Neuroscience letters (Elsevier) China, 03 November 2019
Neuroscience
Key words: Aversive stimulus, Prefrontal cortex, Lateral septal nucleus, Bed nucleus of the stria terminalis, Hypothalamus, Amygdala [more]
Organism: Tree Shrew
Tissue: Brain
Dendritic cell immunotherapy induces anti-tumor effect in a transgenic mouse model of pancreatic ductal adenocarcinoma
American Journal of Cancer Research (NCBI) USA, China, 01 November 2019
Oncology
Key words: Pancreatic ductal adenocarcinoma, DC-based immunotherapy, magnetic resonance imaging [more]
Organism: Mouse
Tissue: Spleen
Pathological State: Cancer
Phospholipase D2 in prostate cancer: protein expression changes with Gleason score
British Journal of Cancer (Nature) UK, Canada, 01 November 2019
Oncology
Key words: Cell growth, Prostate cancer, Time-lapse imaging [more]
Organism: Human
Tissue: Prostate
Pathological State: Cancer
A New Histone Deacetylase Inhibitor Enhances Radiation Sensitivity through the Induction of Misfolded Protein Aggregation and Autophagy in Triple-Negative Breast Cancer
Cancers (MDPI) Taiwan, 01 November 2019
Oncology
Key words: histone deacetylase inhibitor, aggresome, radiation, autophagy, triple-negative breast cancer [more]
Organism: Mouse
Tissue: Breast
Pathological State: Cancer
Directional topography gradients drive optimum alignment and differentiation of human myoblasts
Journal of Tissue Engineering and Regenerative Medicine (Wiley) The Netherlands, 01 November 2019
Regenerative Medicine
Key words: Myoblasts, Myotubes, Polydimethylsiloxane (PDMS), Tissue Engineering, Topography Gradient [more]
Organism: Human
Cell Line: Myoblasts
Responsive exosome nano‐bioconjugates for synergistic cancer therapy
Angewandte Chemie (Wiley) China, Singapore, 31 October 2019
Nanomedicine
Key words: Exosome, immunotherapy, antibodies, cancer, nanoconjugate [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Stress-Induced Metabolic Disorder in Peripheral CD4+ T Cells Leads to Anxiety-like Behavior
CELL (Cell Press) China, 31 October 2019
Neuroscience
Key words: T cell, stress, leukotriene B4, anxiety, purine metabolism, amygdala, AdorA1, IRF-1, xanthine [more]
Organism: Mouse
Cell Line: CD4 T Cells
Distribution of Tyrosine‐Hydroxylase‐Immunoreactive Neurons in the Hypothalamus of Tree Shrews
Journal of Comparative Neurology (Wily) China, 31 October 2019
Neuroscience
Key words: Tyrosine hydroxylase, Hypothalamus, Immunohistochemistry, RRID: AB_2201526, Vasopressin, Aromatic L-amino acid decarboxylase [more]
Organism: Tree Shrew
Tissue: Brain
Histological evidence of chitosan-encapsulated curcumin suppresses heart and kidney damages on streptozotocin-induced type-1 diabetes in mice model
Scientific Reports (Nature) Taiwan, 23 October 2019
Endocrinology
Key words: Experimental models of disease, Immunology [more]
Organism: Mouse
Tissue: Heart, Kidney
Pathological State: Diabetes
Nasal Pneumococcal Density is Associated with Microaspiration and Heightened Human Alveolar Macrophage Responsiveness to Bacterial Pathogens
American Journal of Respiratory and Critical Care Medicine (ATS Journals) UK, Brazil, Germany, Malawi, The Netherlands, 18 October 2019
Immunology
Key words: Nasopharygeal colonization, Microaspiration, Alveolar macrophages, Controlled Human Infection model, CD4+ T cells [more]
Organism: Human
Cell Line: BAL Cells
Human Mesenchymal Stem Cell Response to Lactoferrin-based Composite Coatings
Materials (MDPI) Romania, UK, 18 October 2019
Biological Materials
Key words: mesenchymal stem cells, osteogenic differentiation, lactoferrin, polymer composite [more]
Organism: Human
Cell Line: hMSCs
Facile and efficient encapsulation of antimicrobial peptides via crosslinked DNA nanostructures and their application in wound therapy
Journal of Controlled Release (Elsevier) Singapore, 16 October 2019
Nanomedicine
Key words: DNA hydrogel, S. aureus infection, Wound healing, Antimicrobial peptides, Controlled release, Electrostatic interactions [more]
Organism: Mouse
Tissue: Skin
Pathological State: Staphylococcus aureus Infection
Functional loss of ATRX and TERC activates Alternative Lengthening of Telomeres (ALT) in LAPC4 prostate cancer cells
Molecular Cancer Research (AACR Publications) USA, 14 October 2019
Oncology
Key words: ATRX, TERC, Telomeres, Alternative lengthening of telomeres, Cancer, Prostate cancer, telomerase, gene knockout, CRISPR/Cas [more]
Organism: Human
Pathological State: Cancer
Cell Line: LAPC-4 Cells
Comparing the Osteogenic Potentials and Bone Regeneration Capacities of Bone Marrow and Dental Pulp Mesenchymal Stem Cells in a Rabbit Calvarial Bone Defect Model
International Journal of Molecular Sciences (MDPI) Taiwan, 10 October 2019
Regenerative Medicine
Key words: mesenchymal stem cells, dental pulp stem cells, bone marrow stem cells, bone regeneration, calvarial defect [more]
Organism: Rabbit
Tissue: Bone
Nanoparticulated Honokiol Mitigates Cisplatin-Induced Chronic Kidney Injury by Maintaining Mitochondria Antioxidant Capacity and Reducing Caspase 3-Associated Cellular Apoptosis
Antioxidants (MDPI) Taiwan, 09 October 2019
Biological Materials
Key words: honokiol, cisplatin, kidney injury, oxidative stress, apoptosis, nanotechnology [more]
Organism: Mouse
Tissue: Kidney
Pathological State: Acute Kidney Injury
Loss of smooth muscle CYB5R3 amplifies angiotensin II–induced hypertension by increasing sGC heme oxidation
JCI Insight (American Society of Clinical Investigation) Germany, USA, 03 October 2019
Cardiology
Key words: Vascular Biology, Guanylate cyclase, Hypertension, Nitric oxide [more]
Organism: Mouse
Tissue: Heart, Blood Vessels
Pathological State: Hypertension
Cajaninstilbene Acid Ameliorates Cognitive Impairment Induced by Intrahippocampal Injection of Amyloid-β1-42 Oligomers
Frontiers in Pharmacology (Frontiers Media S.A.) China, 24 September 2019
Pharmacology
Organism: Mouse
Tissue: Brain
Pancreatic stellate cells activated by mutant KRAS-mediated PAI-1 upregulation foster pancreatic cancer progression via IL-8
Theranostics (NCBI) Taiwan, 23 September 2019
Oncology
Key words: pancreatic cancer, PSC, stiffness, organotypic coculture, PAI-1 [more]
Organism: Human
Tissue: Pancreas
Pathological State: Cancer
A Method for Predicting the Success of Pulsinell's Four-Vessel Occlusion Rat Model by LDF Monitoring of Cerebral Blood Flow Decline
Journal of Neuroscience Methods (Elsevier) China, 20 September 2019
Neuroscience
Key words: Global cerebral ischemia-reperfusion injury, Laser Doppler flowmetry, Pulsinelli's four-vessel occlusion method, cerebral blood flow decline [more]
Organism: Rat
Tissue: Brain
Magnesium Sulfate Mitigates the Progression of Monocrotaline Pulmonary Hypertension in Rats
International Journal of Molecular Sciences (MDPI) Taiwan, 18 September 2019
Cardiology
Key words: Right heart failure, oxidation, mitochondria, inflammation, inflammasomes, apoptosis [more]
Organism: Rat
Tissue: Lung
Pathological State: Heart Failure, Hypertension
Diffusion-Weighted MR Imaging to Evaluate Immediate Response to Irreversible Electroporation in a Rabbit VX2 Liver Tumor Model
Journal of Vascular and Interventional Radiology (Elsevier) China, 18 September 2019
Oncology
Organism: Rabbit
Tissue: Liver
Pathological State: Cancer
Disruption of mitochondrial homeostasis with artemisinin unravels anti-angiogenesis effects via auto-paracrine mechanisms
Theranostics (NCBI) Taiwan, USA, 17 September 2019
Endocrinology
Key words: artemisinin, mitochondria, VEGF, angiogenesis, auto-paracrine [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Murine iPSC-derived microglia and macrophage cell culture models recapitulate distinct phenotypical and functional properties of classical and alternative neuro-immune polarisation
Brain, Behavior, and Immunity (Elsevier) Belgium, Germany, Spain, The Netherlands, 13 September 2019
Immunology, Neuroscience
Key words: iPSC, Microglia, Macrophages, Stroke, Neuroinflammation, Interleukin (IL) 13, Polarisation, Classical activation, Alternative activation [more]
Organism: Mouse
Tissue: Brain
The Effect of Wharton Jelly-Derived Mesenchymal Stromal Cells and Their Conditioned Media in the Treatment of a Rat Spinal Cord Injury
International Journal of Molecular Sciences (MDPI) Czech Republic, 12 September 2019
Neuroscience
Key words: spinal cord injury, mesenchymal stem cells, Wharton's jelly, conditioned medium, cell secretome, cell therapy [more]
Organism: Rat
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Next-generation computational tools for interrogating cancer immunity
Nature Reviews Genetics (Nature) Austria, 12 September 2019
Oncology
Key words: Antigen presentation, Cancer genetics, Cancer genomics, Cancer immunotherapy, Computational biology and bioinformatics, Tumor immunology
Regulation of TRIF-mediated innate immune response by K27-linked polyubiquitination and deubiquitination
Nature Communications (Nature) China, 11 September 2019
Immunology
Key words: Bacterial Infection, Innate immune cells, Pattern recognition receptors, Ubiquitylation [more]
Organism: Mouse
Tissue: Lung
Region-specific parasympathetic nerve remodeling in the left atrium contributes to creation of a vulnerable substrate for atrial fibrillation
JCI Insight (American Society of Clinical Investigation) USA, 10 September 2019
Neuroscience
Organism: Dog
Tissue: Heart
Region specific parasympathetic nerve remodeling in the left atrium contributes to creation of a vulnerable substrate for atrial fibrillation
The Journal of Clinical Investigation (Am Soc Clin Investig) USA, 10 September 2019
Cardiology
Organism: Mouse
Tissue: Heart
Calcium‐sensing Receptors in Chondrocytes and Osteoblasts Are Required for Callus Maturation and Fracture Healing in Mice
Journal of Bone and Mineral Research (Wiley) USA, 09 September 2019
Osteology
Key words: chondrogenesis, osteogenesis, endochondral bone formation, cartilage, chondrocyte, osteoblast, CaSR knockout, unfixed fracture, fracture healing
Worm-Based Alternate Assessment of Probiotic Intervention against Gut Barrier Infection
Nutrients (MDPI) South Korea, 08 September 2019
Immunology
Key words: Gut health, Probiotics, Caenorhabditis elegans, Epithelial barrier infection [more]
Organism: Mouse
Tissue: Colon
Pathological State: Worm Infestation
Loss of smooth muscle CYB5R3 amplifies angiotensin-II induced hypertension by increasing sGC heme oxidation
The Journal of Clinical Investigation (American Society for Clinical Investigation) USA, Germany, 05 September 2019
Cardiology
Organism: Mouse
Tissue: Heart
ATMIN is a tumor suppressor gene in lung adenocarcinoma
Cancer Research (AACR Publications) UK, 03 September 2019
Oncology
Metabolic targeting of HIF-1α potentiates the therapeutic efficacy of oxaliplatin in colorectal cancer
Oncogene (Nature) Taiwan, 02 September 2019
Oncology
Key words: Cancer therapeutic resistance, Tumor angiogenesis [more]
Organism: Mouse
Tissue: Blood Vessels
Pathological State: Cancer
Novel Semi-Replicative Retroviral Vector Mediated Double Suicide Gene Transfer Enhances Antitumor Effects in Patient-Derived Glioblastoma Models
Cancers (MDPI) South Korea, 31 August 2019
Oncology
Key words: glioblastoma, patient-derived glioblastoma stem-like cells, semi- and pseudotyped-retroviral replicating vector, dual suicide gene therapy, bystander effect [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
The neuronal oxygen-sensing pathway controls postnatal vascularization of the murine brain
The FASEB Journal (FASEB) Germany, Switzerland, 30 August 2019
Neuroscience
Key words: PHD, HIF, VEGF, Adrenomedullin, Cerebral angiogenesis [more]
Organism: Mouse
Tissue: Brain
Insights into Early Recovery from Influenza Pneumonia by Spatial and Temporal Quantification of Putative Lung Regenerating Cells and by Lung Proteomics
Cells (MDPI) Singapore, 26 August 2019
Pulmonology
Key words: influenza, pneumonia, lung regeneration, stem cells, comparative quantification, P63, KRT5, proliferating alveolar type II cells, proteomics [more]
Organism: Mouse
Tissue: Lung
Pathological State: Pneumonia
Macrophage HIF‐2α regulates tumor‐suppressive Spint1 in the tumor microenvironment
Molecular Carcinogenesis (Wiley) Germany, 22 August 2019
Oncology
Key words: HAI‐1, HGF, hypoxia, proliferation, tumor‐associated macrophages [more]
Organism: Mouse
Tissue: Lung, Xenograft Tumor
Pathological State: Cancer
Nononcogenic restoration of the intestinal barrier by E. coli–delivered human EGF
The Journal of Clinical Investigation (Am Soc Clin Investig) South Korea, 22 August 2019
Microbiology
Organism: Mouse
Tissue: Small Intestine
Pathological State: Colitis
Early TLR4 inhibition reduces hippocampal injury at puberty in a rat model of neonatal hypoxic-ischemic brain damage via regulation of neuroimmunity and synaptic plasticity
Experimental Neurology (Elsevier) China, 20 August 2019
Neuroscience
Key words: Hypoxia-ischemia(HI), Neuroprotection, Brain injuries, Hippocampus, Toll-like receptor 4, Rat model [more]
Organism: Rat
Tissue: Brain
Pathological State: Cerebral Ischemia
Microstimulation of primate neocortex targeting striosomes induces negative decision-making
European Journal of Neuroscience (Wiley) USA, 20 August 2019
Neuroscience
Key words: anterior cingulate cortex, approach-avoidance, microstimulation, orbitofrontal cortex, striatum [more]
Organism: Monkey
Tissue: Brain
IL‐10 from plasmacytoid dendritic cells promotes angiogenesis in the early stage of endometriosis
The Journal of Pathology (Wiley) Taiwan, 16 August 2019
Reproductive Medicine
Key words: Angiogenesis, Endometriosis, IL-10, Plasmacytoid dendritic cell, Zebrafish [more]
Organism: Human, Mouse
Tissue: Endometrium
Pathological State: Endometriosis
Targeting the IL-17 receptor using liposomal spherical nucleic acids as topical therapy for psoriasis
Journal of Investigative Dermatology (Elsevier) USA, 15 August 2019
Dermatology
Pathological State: Psoriasis
JAK‐STAT inhibition impairs K‐RAS‐driven lung adenocarcinoma progression
International Journal of Cancer (Wiley) Austria, Hungary, 12 August 2019
Oncology
Key words: non-small cell lung cancer, lung adenocarcinoma (AC), Kirsten rat sarcoma viral proto-oncogene (K-RAS), Janus kinase (JAK), ruxolitinib, cell-line derived xenografts, genetically engineered mouse models, tumor microenvironment (TME), tumor promotinginflammation [more]
Organism: Mouse
Tissue: Lung, Xenograft Tumor
Pathological State: Cancer
Resveratrol prevents chronic intermittent hypoxia-induced cardiac hypertrophy by targeting the PI3K/AKT/mTOR pathway
Life Science (Elsevier) China, 11 August 2019
Cardiology
Key words: Resveratrol, Chronic intermittent hypoxia, Cardiac hypertrophy, mTOR [more]
Organism: Rat
Tissue: Heart
Pathological State: Cardiac Hypertrophy
Phosphatidylethanolamine binding protein-4 (PEBP4) is increased in IgA nephropathy and is associated with IgA-positive B-cells in affected kidneys
Journal of Autoimmunity (Elsevier) UK, 09 August 2019
Immunology
Key words: IgA nephropathy (IgAN), PEBP4, Urine, Proteomics, Biomarker, B-Cells [more]
Organism: Human
Tissue: Kidney
Pathological State: IgA nephropathy
Antibiotics drive microbial imbalance and vitiligo development in mice
Journal of Investigative Dermatology (Elsevier) USA, Kazakhstan, 09 August 2019
Dermatology
Key words: Vitiligo, Microbiome, Pseudomonas, T cells [more]
Organism: Mouse
Tissue: Small Intestine, Colon
Pathological State: Vitiligo
Overexpression of Histone H3 Lysine 27 Trimethylation Is Associated with Aggressiveness and Dedifferentiation of Thyroid Cancer
Endocrine Pathology (Springer) Taiwan, 08 August 2019
Oncology
Key words: H3K27me3, EZH2, Thyroid cancer, Immunohistochemistry [more]
Organism: Human
Tissue: Thyroid
Pathological State: Cancer
Senescence‐associated tissue microenvironment promotes colon cancer formation through the secretory factor GDF15
Aging Cell (Wiley) USA, 06 August 2019
Cell Biology
Key words: Colon organoids, Colorectal cancer, GDF15, microenivronment, senescence [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Cancer-Derived VEGF-C Increases Chemokine Production in Lymphatic Endothelial Cells to Promote CXCR2-Dependent Cancer Invasion and MDSC Recruitment
Cancers (MDPI) Taiwan, 06 August 2019
Oncology
Key words: vascular endothelial growth factor-C, CXC chemokine receptor 2, lymphovascular niche, myeloid-derived suppressor cells [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
Analysis of Telomere Lengths in p53 Signatures and Incidental Serous Tubal Intraepithelial Carcinomas Without Concurrent Ovarian Cancer
The American journal Surgical Pathology (Wolters Kluwer) USA, 01 August 2019
Oncology
Key words: ovarian cancer precursor, fallopian tube, p53 signature, serous tubal intraepithelial carcinoma, telomere
Increased ILC3s associated with higher levels of IL-1 aggravates inflammatory arthritis in mice lacking phagocytic NADPH oxidase
European Journal of Immunology (Wiley) Taiwan, Japan, USA, 26 July 2019
Rheumatology
Key words: Innate lymphoid cells, Chronic granulomatous disease, NADPH oxidase, Reactive oxygen species, Serum-induced arthritis [more]
Organism: Mouse
Tissue: Bone, Connective Tissue
Pathological State: Arthritis
Phthalate exposure alters gut microbiota composition and IgM vaccine response in human newborns
Food and Chemical Toxicology (Elsevier) Taiwan, USA, 26 July 2019
Toxicology
Key words: Di-(2-ethylhexyl) phthalate, Intravenous infusion, Microbiota, Anti-HBsAg-IgM, Newborn
An Amyloid-β Targeting Chemical Exchange Saturation Transfer Probe for In Vivo Detection of Alzheimer's Disease
ACS Chemical Neuroscience (ACS Publications) China, 25 July 2019
Neuroscience
Key words: Alzheimer's disease, Amyloid-β, Magnetic resonance imaging, Chemical exchange saturation transfer, Angiopep-2 [more]
Organism: Mouse
Tissue: Brain
Pathological State: Alzheimer's disease
Synergistic effect of NELL-1 and an ultra-low dose of BMP-2 on spinal fusion
Tissue Engineering Part A (Mary Ann Liebert Inc.) Singapore, China, 24 July 2019
Regenerative Medicine
Organism: Pig
Cell Line: BMSC
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP
Nature Communications (Nature) Italy, France, USA, UK, 24 July 2019
Oncology
Key words: Cancer, Molecular biology [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
DIS3L2 promotes progression of hepatocellular carcinoma via hnRNP U-mediated alternative splicing
Cancer Research (AACR Publications) China, 22 July 2019
Oncology
Key words: HCC, DIS3L2, hnRNP U, Alternative splicing, Rac1b [more]
Organism: Human
Tissue: Liver
Pathological State: Cancer
Selective androgen receptor modulators (SARMs) have specific impacts on the mouse uterus
Journal of Endocrinology (bioscientifica) Ireland, 18 July 2019
Reproductive Medicine
Key words: Uterus, Endometrium, Androgen, SARM, Andarine, GTx-024, Enobosarm, 15 Ostarine, Danazol, DHT [more]
Organism: Mouse
Tissue: Uterus
Sp1 in Astrocyte Is Important for Neurite Outgrowth and Synaptogenesis
Molecular Neurobiology (Springer) Taiwan, USA, 18 July 2019
Neuroscience
Key words: Sp1, Astrocyte, Neurite outgrowth, Synaptogenesis [more]
Organism: Mouse
Tissue: Brain
Neutrophil extracellular traps and fibrocytes in ST-segment elevation myocardial infarction
Basic Research in Cardiology (Springer) Austria, 16 July 2019
Cardiology
Key words: ST-segment elevation myocardial infarction, Neutrophil extracellular traps, Fibrocytes Thrombosis [more]
Organism: Human
Tissue: Heart
Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface
Nature Communications (Nature) UK, 16 July 2019
Microbiology, Immunology
Key words: Infection, Innate immunity, Pathogens, Respiratory tract diseases [more]
Organism: Human
Pathological State: Streptococcus Infection
Cell Line: Mucosal cells
B lymphocytes directly contribute to tissue fibrosis in patients with IgG4-related disease
Journal of Allergy and Clinical Immunology (Elsevier) Italy, USA, Japan, 15 July 2019
Allergy Research
Key words: IgG4, IgG4-related disease, B cells, plasmablasts, fibrosis, fibroblasts, rituximab, lysyl oxidase homolog 2, plateletderived growth factor [more]
Organism: Human
Tissue: Pancreas, Lymphoid Tissue,
Pathological State: IgG4-Related Disease
Pleiotropic Effects of Epithelial Mesenchymal Crosstalk on Head and Neck Cancer: EMT and beyond
Cancer Microenvironment (Springer) Austria, 11 July 2019
Oncology
Key words: IL-6, EMT, JAK/STAT3/Snail signalling, radiochemotherapy, therapy resistance, conditioned medium [more]
Organism: Human
Tissue: Head and Neck
Pathological State: Cancer
The Lymphoma-Associated Macrophages-To-Hodgkin-Reed-Sternberg Cells Ratio Is A Poor Prognostic Factor In Classic Hodgkin Lymphoma Patients
Clinical Lymphoma Myeloma and Leukemia (Elsevier) Czech Republic, 05 July 2019
Oncology
Key words: Hodgkin lymphoma, macrophage, prognosis, microenvironment [more]
Organism: Human
Pathological State: Cancer
miR-103/107 prolong Wnt/β-catenin signaling and colorectal cancer stemness by targeting Axin2
Scientific Reports (Nature) Taiwan, 04 July 2019
Oncology
Key words: Colon cancer, Metastasis [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Entrapment of N-Hydroxyphthalimide Carbon Dots in Different Topical Gel Formulations: New Composites with Anticancer Activity
Pharmaceutics (MDPI) Romania, 01 July 2019
Oncology
Key words: composite, N-hydroxyphthalimide, carbon dots, polymer gels, antitumoral activity [more]
Organism: Human
Cell Line: MDA-MB-231 cells
Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons
EBioMedicine (THE LANCET) Japan, 29 June 2019
Neuroscience
Key words: Amyotrophic lateral sclerosis (ALS), Fused in sarcoma (FUS), Axon branching, Fos-B, Nerve organoid, Human-induced pluripotent stem cell (hiPSC)-derived motor neuron [more]
Organism: Human
Tissue: Spinal Cord
Pathological State: Amyotrophic Lateral Sclerosis
Fbxw7 increases CCL2/7 in CX3CR1hi macrophages to promote intestinal inflammation
The Journal of Clinical Investigation (American Society for Clinical Investigation) China, 27 June 2019
Immunology
Organism: Mouse
Tissue: Colon
Pathological State: Colitis
Amelioration of Experimentally Induced Arthritis by Reducing Reactive Oxygen Species Production through the Intra-Articular Injection of Water-Soluble Fullerenol
Nanomaterials (MDPI) China, Taiwan, 23 June 2019
Nanomedicine
Key words: experimental arthritis, intra-articular injection, reactive oxygen species, rheumatoid arthritis, water-soluble fullerenol [more]
Organism: Rat
Tissue: Bone, Connective Tissue
Pathological State: Rheumatoid Arthritis
Cytotoxic T-cells and their activation status are independent prognostic markers in meningiomas
Clinical Cancer Research (AACR Publications) Germany, 21 June 2019
Immunology, Oncology
Key words: Clinically aggressive meningioma, T-cell infiltration, primary and recurrent tumors TILs, PD-1 [more]
Organism: Human
Tissue: Brain
Pathological State: Cancer
Differential expression of Plg-RKT and its effects on migration of proinflammatory monocyte and macrophage subsets
Blood (American Society of Hematology) Austria, USA, 20 June 2019
Cardiology
Organism: Human
Tissue: Adipose Tissue
Specific inhibition of the classical complement pathway prevents C3 deposition along the dermal-epidermal junction in bullous pemphigoid
Journal of Investigative Dermatology (Elsevier) Austria, USA, 20 June 2019
Dermatology
Gasdermin D protects against noninfectious liver injury by regulating apoptosis and necroptosis
Cell Death & Disease (Nature) USA, China, 17 June 2019
Hepathology
Key words: Cell death and immune response, Innate immunity [more]
Organism: Mouse
Tissue: Liver
Pathological State: Liver Injury
C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice
Nature Communications Biology (Nature) The Netherlands, Germany, 14 June 2019
Oncology
Key words: Cancer metabolism, Cell growth [more]
Organism: Mouse
Tissue: Bone Marrow
Fc glycan-mediated regulation of placental antibody transfer
CELL (Cell Press) USA, Belgium, 13 June 2019
Reproductive Medicine, Immunology
Key words: antibody functionality, antibody glycosylation, trans-placental transfer, maternal vaccination, ADCC, neonatal immunology [more]
Organism: Human
Tissue: Placenta
The PPARγ Agonist Rosiglitazone Suppresses Syngeneic Mouse SCC (Squamous Cell Carcinoma) Tumor Growth through an Immune-Mediated Mechanism
Molecules (MDPI) USA, 11 June 2019
Oncology, Immunology
Key words: peroxisome proliferator activated receptor gamma, rosiglitazone, T-cells, myeloid cells, anti-tumor immunity [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Optimisation of multiplex immunofluorescence for a non-spectral fluorescence scanning system
Journal of Immunological Methods (Elsevier) Australia, 08 June 2019
Medical Imaging
Key words: Fluorescence microscopy, Imaging, Immunohistochemistry, T cells, Colorectal [more]
Organism: Human
Tissue: Colon
Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis
Nature (Nature) South Africa, USA, Kenya, Mexico, UK, Denmark, 05 June 2019
Immunology
Key words: Innate lymphoid cells, Tuberculosis [more]
Organism: Human
Tissue: Lung
Pathological State: Tuberculosis
Role of the PI3K‑mTOR autophagy pathway in nerve damage in rats with intermittent hypoxia‑aggravated whole brain ischemia
Molecular Medicine Reports (Spandidos Publications) China, 04 June 2019
Neuroscience
Organism: Rat
Tissue: Brain
Pathological State: Cerebral Ischemia
Heat-killed Mycobacterium tuberculosis prime-boost vaccination induces myeloid-derived suppressor cells with spleen dendritic cell-killing capability
The Journal of Clinical Investigation (American Society for Clinical Investigation) Germany, South Africa, 04 June 2019
Immunology
Organism: Mouse
Cell Line: BM-MDSCs and BM-DCs cell
Abnormal expression of b10 cell frequencies: possible relation to pathogenesis and disease severity of aplastic anemia
Revista da Associação Médica Brasileira (SciELO Brasil) China, 03 June 2019
Hematology
Key words: Anemia, Aplastic, B-Lymphocytes, Regulatory, Interleukin-10 [more]
Organism: Human
Cell Line: Bone marrow-derived mononuclear cells
Lysine 68 acetylation directs MnSOD as a tetrameric detoxification complex versus a monomeric tumor promoter
Nature Communications (Nature) USA, South Korea, 03 June 2019
Oncology
Key words: Breast cancer, Cancer, Enzyme mechanisms [more]
Organism: Mouse
Tissue: Breast
Pathological State: Cancer
Micro RNA‐133 Suppresses ZFHX 3‐dependent Atrial Remodeling and Arrhythmia
Acta Physiologica (Wiley) Taiwan, 01 June 2019
Cardiology
Key words: atrial ectopy, cardiac remodelling, connexin43, MicroRNA‐133, Wnt/calcium signalling, ZFHX3 [more]
Organism: Mouse
Tissue: Heart
Pathological State: Arrhythmia
AIF-regulated oxidative phosphorylation supports lung cancer development
Cell Research (Nature) China, Austria, France, Germany, Canada, Belgium, Sweden, 27 May 2019
Oncology
Key words: Mechanisms of disease, Non-small-cell lung cancer [more]
Organism: Mouse
Tissue: Lung
Pathological State: Cancer
Cancer Stem-Cell Marker CD44v9-Positive Cells Arise From Helicobacter pylori–Infected CAPZA1-Overexpressing Cells
Cellular and Molecular Gastroenterology and Hepatology (Elsevier) Japan, 27 May 2019
Oncology, Microbiology
Key words: Autophagy, CagA, Cancer Stem Cells, CD44v9, Eradication Therapy [more]
Organism: Human
Tissue: Stomach
Pathological State: Cancer
LINGO-1 deficiency promotes nerve regeneration through reduction of cell apoptosis, inflammation, and glial scar after spinal cord injury in mice
Experimental Neurology (Elsevier) China, 25 May 2019
Neuroscience
Key words: LINGO-1 knockout, Spinal cord injury, Cell apoptosis, Inflammation, Glial scar, Nerve regeneration [more]
Organism: Mouse
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer's Disease Patients
Cell Stem Cell (Cell Press) USA, 23 May 2019
Neuroscience
Key words: human neurogenesis, adult neurogenesis, neural stem cells, neurogenesis in aging, cognitive dysfunction, aging, Alzheimer's disease [more]
Organism: Human
Tissue: Brain
Pathological State: Alzheimer's Disease
Near-Infrared Fluorescent Endoscopic Image-guided Photothermal Ablation Therapy of Colorectal Cancer using Dual-modal Gold Nanorods Targeting Tumor Infiltrating Innate Immune Cells in Transgenic TS4 CRE/APCloxΔ468 Mouse Model
ACS Applied Materials & Interfaces (ACS Publications) USA, 22 May 2019
Oncology
Key words: colon cancer, endoscopic image-guided therapy, nanomedicine, interventional oncology, photothermal therapy [more]
Organism: Mouse
Tissue: Colon
Pathological State: Polyps
High Activation Of STAT5A Drives Peripheral T-Cell Lymphoma And Leukemia
Haematologica (The Ferrata Sorti Foundation) Austria, Czech Republic, Germany, Canada, 21 May 2019
Oncology
Key words: Hematopoiesis, Lymphocytes, Lymphoproliferative Disorders, PTCLSTAT5 [more]
Organism: Mouse
Tissue: Lymphoid Tissue
Pathological State: Cancer
The effect of 808 nm and 905 nm wavelength light on recovery after spinal cord injury
Scientific Reports (Nature) Czech Republic, USA, 21 May 2019
Regenerative Medicine
Key words: Spinal cord diseases, Spinal cord injury [more]
Organism: Rat
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Growth and cellular patterning during fetal human inner ear development studied by a correlative imaging approach
BMC Developmental Biology (Springer) Austria, 20 May 2019
Developmental Biology
Organism: Human
Tissue: Bone
Nano-formulated Curcumin (LipodisqTM) modulates the local inflammatory response, reduces glial scar and preserves the white matter after spinal cord injury in rats
Neuropharmacology (Elsevier) Czech Republic, 17 May 2019
Nanomedicine
Key words: Spinal cord injury, Nanocurcumin, Inflammatory response, Neuroregeneration, Astrogliosis, Axonal growth [more]
Organism: Mouse
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Amentoflavone Effectively Blocked the Tumor Progression of Glioblastoma via Suppression of ERK/NF-B Signaling Pathway
The American Journal of Chinese Medicine (World Scientific) Taiwan, 17 May 2019
Oncology
Key words: Amentoflavone, Glioblastoma, Anticancer, ERK, NF-κB [more]
Organism: Mouse
Tissue: Xenograft Tumor, Liver
Pathological State: Cancer
Potential Effects of CXCL9 and CCL20 on Cardiac Fibrosis in Patients with Myocardial Infarction and Isoproterenol-Treated Rats
Journal of Clinical Medicine (MDPI) Taiwan, 11 May 2019
Cardiology
Key words: myocardial infarction, cardiac fibrosis, CXCL9, CCL20, isoproterenol [more]
Organism: Rat
Tissue: Heart
Pathological State: Cardiac Fibrosis
In vitro biological response of cancer and normal tissue cells to proton irradiation not affected by an added magnetic field
Radiotherapy and Oncology (Elsevier) The Netherlands, 11 May 2019
Oncology
Key words: Protons, MRI, Tumor, Normal tissue, Organoids [more]
Organism: Human
Cell Line: Human embryonic kidney cells (HEK293) and human lung adenocarcinoma cells (A549)
Effects of Hydroxychloroquine on the Human Placenta–Findings from In Vitro Experimental Data and a Systematic Review
Reproductive Toxicology (Elsevier) UK, 10 May 2019
Reproductive Medicine
Key words: Hydroxychloroquine, Placenta, TLRs, TLR 7, TLR 9, Inflammation, Toxicology, Safety, Pregnancy, SLEAPS [more]
Organism: Human
Tissue: Placenta
Slow delivery immunization enhances HIV neutralizing antibody and germinal center responses via modulation of immunodominance
CELL (Cell Press) USA, Sweden, 09 May 2019
Immunology
Key words: HIV vaccine, non-human primates, rhesus macaque genome, FNA, GC- TFH, memory B cells, somatic hypermutation, affinity maturation, immune complexes [more]
Organism: Mouse
Tissue: Lymphoid Tissue
Pathological State: HIV Infection
Multimodal [18F]FDG PET/CT is a direct readout for inflammatory bone repair: a longitudinal study in TNFα transgenic mice
Journal of Bone and Mineral Research (Wiley) Austria, 07 May 2019
Osteology
Key words: µPET/CT, 18F‐FDG, 18F‐NaF, bone healing, experimental arthritis, TNF blockade [more]
Organism: Human
Tissue: Bone, Connective Tissue
Directional Topography Influences Adipose Mesenchymal Stromal Cell Plasticity: Prospects for Tissue Engineering and Fibrosis
Stem Cells International (Hindawi Publishing Corporation) The Netherlands, Brazil, China, 05 May 2019
Stem Cell Research
Organism: Human
Cell Line: Adipose tissue derived stromal cells (ADSC)
Endoplasmic reticulum stress is involved in stress-induced hypothalamic neuronal injury in rats via the PERK-ATF4-CHOP and IRE1-ASK1-JNK pathways
Frontiers in Cellular Neuroscience (Frontiers Media S.A.) China, 03 May 2019
Neuroscience
Key words: hypothalamus, stress, neuronal injury, PERK-ATF4-CHOP pathway, IRE1-ASK1-JNK pathway [more]
Organism: Rat
Tissue: Brain
Pathological State: Brain Injury
CD11b+ cells markedly express the itch cytokine interleukin‐31 in polymorphic light eruption
British Journal of Dermatology (Wiley) Austria, 03 May 2019
Dermatology
Organism: Human
Tissue: Skin
Positive PD‑L1 expression is predictive for patients with advanced EGFR wild‑type non‑small cell lung cancer treated with gemcitabine and cisplatin
Oncology Letters (Spandidos Publications) China, 02 May 2019
Oncology
Key words: programmed death ligand-1, checkpoint, immunotherapy, non-small cell lung cancer, prognosis [more]
Organism: Human
Tissue: Lung
Pathological State: Cancer
Exosomal transfer of bone marrow mesenchymal stem cells-derived miR340 attenuates endometrial fibrosis
Biology Open (The Company of Biologists) China, 01 May 2019
Stem Cell Research
Organism: Rat
Tissue: Uterus
Pathological State: Endometriosis
An improved method of culturing somatotropic cells from rat adenohypophysis
Tissue and Cell (Elsevier) China, 30 April 2019
Biological Methods
Key words: Pericytes, Improved method, Primary culture, Somatotropic cells [more]
Organism: Rat
Cell Line: Pericytes
Promyelocytic leukemia zinc finger is involved in the formation of deep layer cortical neurons
Journal of Biomedical Science (Springer) Taiwan, 26 April 2019
Neuroscience
Key words: Promyelocytic leukemia zinc finger, Plzf, luxoid mice, Cortical neuron [more]
Organism: Mouse
Tissue: Brain
Exercise Alleviates Osteoporosis in Rats with Mild Chronic Kidney Disease by Decreasing Sclerostin Production
International Journal of Molecular Sciences (MDPI) Taiwan, 25 April 2019
Osteology, Nephrology
Key words: exercise, chronic kidney disease, osteoporosis, sclerostin, chronic kidney disease–mineral bone disorder [more]
Organism: Rat
Tissue: Bone
Pathological State: Kidney Disease
Wound Age Estimation by Neutrophil Migration Distance.
Fa yi xue za zhi (Europe PMC) China, 25 April 2019
Immunology
Th2-TRMs maintain life-long allergic memory in experimental asthma in mice
Frontiers in Immunology (Frontiers Media S.A.) Austria, 24 April 2019
Immunology
Organism: Mouse
Tissue: Lung
Pathological State: Asthma
YWHAE promotes proliferation, metastasis, and chemoresistance in breast cancer cells
Kaohsiung Journal of Medical Sciences (Wiley) Taiwan, 18 April 2019
Oncology
Key words: 14‐3‐3ε, breast cancer, chemoresistance, YWHAE [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
Toll‑like receptor 4 plays a tumor‑suppressive role in cutaneous squamous cell carcinoma
International Journal of Oncology (Spandidos Publications) Japan, 17 April 2019
Oncology
Key words: Toll-like receptor 4, cutaneous squamous cell carcinoma, differentiation, CD44, migration, invasion, filopodia [more]
Organism: Human
Tissue: Skin
Pathological State: Cancer
Functional CD3+ CD8+ PD-1-T cells accumulation and PD-L1 expression increases during tumor invasion in DCIS of the breast
Clinical Breast Cancer (Elsevier) China, USA, 16 April 2019
Oncology
Key words: DCIS, Opal technique PDl-1, PD-1, immune, microenvironment [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
Low cd8+ t cell infiltration and high pd-l1 expression are associated with level of cd44+/cd133+ cancer stem cells and predict an unfavorable prognosis in pancreatic cancer
Cancers (MDPI) Taiwan, 15 April 2019
Oncology
Key words: pancreatic cancer, T cells, cancer stem cells, CD8, PD-L1, CD44, CD133, immunotherapy [more]
Organism: Human
Tissue: Pancreas
Pathological State: Cancer
Metastatic Colorectal Cancer Rewrites Metabolic Program Through a Glut3-YAP-dependent Signaling Circuit
Theranostics (Ivyspring) Taiwan, 13 April 2019
Oncology
Key words: cancer metabolism, colorectal cancer, glucose transporter, metastasis, YAP [more]
Organism: Mouse
Tissue: Xenograft Tumor, Lung
Pathological State: Cancer
Interrelations of Sphingolipid and Lysophosphatidate Signaling With Immune System in Ovarian Cancer
Computational and Structural Biotechnology Journal (Elsevier) Austria, Germany, Belgium, Switzerland, Canada, 10 April 2019
Oncology
Key words: Sphingolipid/lysophosphatidate system, On-site immune response, Patient-specific expression data sets, Integrative analysis algorithm, Patient stratification, From systems biology to systems medicine [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
Au Nanoparticles with Enzyme-Mimicking Activities Ornamented ZIF-8 for Highly Efficient Photodynamic Therapy
Biomaterials Science (Royal Society of Chemistry) China, 04 April 2019
Nanomedicine
Key words: AuNPs nanozyme, nano metal-organic frameworks, tumor hypoxia, photodynamic therapy [more]
Organism: Mouse
Tissue: Breast
Pathological State: Cancer
Associations between hepatitis etiology and immune cell infiltration in or around hepatocellular carcinoma
Cancer Research (AACR Publications) USA, 03 April 2019
Oncology, Virology
Organism: Human
Tissue: Liver
Pathological State: Cancer
The sodium–glucose co-transporter 2 inhibitor empagliflozin attenuates cardiac fibrosis and improves ventricular hemodynamics in hypertensive heart failure rats
Cardiovascular Diabetology (Springer) Taiwan, 01 April 2019
Cardiology
Key words: SGLT2 inhibitor, Empagliflozin, Hypertensive, Heart failure, Cardiac fibrosis, Hemodynamics, High-fat, PPARα, ACADM [more]
Organism: Rat
Tissue: Heart
Pathological State: Cardiac Fibrosis, Heart Failure
Novel CHK1 inhibitor MU380 exhibits significant single-agent activity in TP53-mutated chronic lymphocytic leukemia cells
Haematologica (Ferrata Storti Foundation) Czech Republic, 01 April 2019
Oncology
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Antrodia cinnamomea induces anti-tumor activity by inhibiting the STAT3 signaling pathway in lung cancer cells
Scientific Reports (Nature) Taiwan, USA, Malaysia, 26 March 2019
Oncology
Key words: Drug development, Lung cancer [more]
Organism: Mouse
Tissue: Lung
PIP4K2A as a negative regulator of PI3K in PTEN-deficient glioblastoma
Journal of Experimental Medicine (Rockefeller University Press) South Korea, China, USA, 21 March 2019
Oncology, Cell Biology
Key words: Solid Tumors, Neuroscience [more]
Organism: Human
Tissue: Brain
Pathological State: Cancer
Designing pH-Triggered Drug Release Iron Oxide Nanocomposites for MRI Guided Photothermal-Chemoembolization Therapy of Liver Orthotopic Cancer
Biomaterials Science (Royal Society of Chemistry) China, 19 March 2019
Nanomedicine
Key words: pH-Triggered Drug Release, Iron Oxide Nanocomposites, MRI, Photothermal-Chemoembolization Therapy, Liver Orthotopic Cancer [more]
Organism: Rat
Tissue: Liver
Pathological State: Cancer
γδT cells suppress liver fibrosis via strong cytolysis and enhanced NK cell-mediated cytotoxicity against hepatic stellate cells
Frontiers in Immunology (Frontiers Media S.A.) China, Germany, Belgium, USA, 15 March 2019
Immunology
Key words: fibrosis, γδT cell, NKp46, cytotoxicity, γδT1, γδT17, CD137, cell crosstalk [more]
Organism: Mouse
Tissue: Liver
Pathological State: Liver Fibrosis
Traffic-related particulate matter exposure induces nephrotoxicity in vitro and in vivo
Free Radical Biology and Medicine (Elsevier) Taiwan, 14 March 2019
Toxicology
Key words: Nephrotoxicity, Autophagy, Apoptosis, Endoplasmic reticulum stress [more]
Organism: Rat
Tissue: Kidney
ErbB3 Ligand Heregulin1 Is a Major Mitogenic Factor for Uncontrolled Lung Cancer Cell Proliferation
Neoplasia (Elsevier) China, 02 March 2019
Oncology
Key words: ErbB3, Heregulin1, Lung Cancer [more]
Organism: Human
Tissue: Lung
Pathological State: Cancer
Sulfasalazine could modulate the CD44v9‐xCT system and enhance cisplatin‐induced cytotoxic effects in metastatic bladder cancer
Cancer Science (NCBI) Japan, 01 March 2019
Oncology
Key words: bladder cancer, CD44v9, cisplatin, metastasis, sulfasalazine [more]
Organism: Mouse
Tissue: Lung
Pathological State: Cancer
Expression of the neonatal Fc-receptor in placental-fetal endothelium and in cells of the placental immune system
Placenta (Elsevier) Austria, 28 February 2019
Reproductive Medicine
Key words: Human placenta, FcRn, syncytiotrophoblast, placental-fetal endothelial cells, placental macrophages, IgG transport [more]
Organism: Human
Tissue: Placenta
High-risk human papillomavirus oncogenes disrupt the Fanconi anemia DNA repair pathway by impairing localization and de-ubiquitination of FancD2
PLoS Pathogens (PLOS) USA, 28 February 2019
Virology
Key words: Immunoblotting, Oncogenes, DNA repair, Phosphorylation, Human papillomavirus, HPV-16, Cell signaling, Small interfering RNAs [more]
Organism: Human
Pathological State: HPV Infection
Cell Line: Primary human foreskin keratinocytes (HFKs)
Metabolic cross-talk between human bronchial epithelial cells and internalized Staphylococcus aureus as a driver for infection
Molecular and Cellular Proteomics (American Society for Biochemistry and Molecular Biology) Germany, The Netherlands,, 26 February 2019
Immunology
Key words: Staphylococcus aureus, in vivo proteomics, population heterogeneity, persister, bronchial epithelial cells, Apoptosis*, Autophagy Bacteria, Energy metabolism, Host-Pathogen Interaction, Infectious disease [more]
Organism: Human
Pathological State: Staphylococcus aureus Infection
Cell Line: Bronchial epithelial cells
Ligase 3–mediated end-joining maintains genome stability of human embryonic stem cells
The FASEB Journal (FASEB) Czech Republic, USA, 26 February 2019
Stem Cell Research
Key words: base excision repair, PARP1, 53BP1, pluripotent stem cells, alternative DNA end-joining [more]
Organism: Human
Cell Line: Human embryonic stem cells
Higher CXCL16 exodomain is associated with aggressive ovarian cancer and promotes the disease by CXCR6 activation and MMP modulation
Scientific Reports (Nature) USA, 21 February 2019
Oncology
Key words: Cancer, Ovarian cancer [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
State-of-the-Art of Profiling Immune Contexture in the Era of Multiplexed Staining and Digital Analysis to Study Paraffin Tumor Tissues
Cancers (MDPI) USA, 20 February 2019
Medical Image Analysis
Key words: immune profiling, cancer tissues, multiplexed methodologies, image analysis, spatial analysis
Long noncoding RNA AOC4P regulates tumor cell proliferation and invasion by epithelial–mesenchymal transition in gastric cancer
Therapeutic Advances In Gastroenterology (SAGE Journals) China, 19 February 2019
Oncology
Key words: AOC4P, long noncoding RNAs, metastasis, prognosis, stomach neoplasm [more]
Organism: Human
Tissue: Stomach
Pathological State: Cancer
B-type natriuretic peptide enhances fibrotic effects via matrix metalloproteinase-2 expression in the mouse atrium in vivo and in human atrial myofibroblasts in vitro
Translational Research (Elsevier) Taiwan, 19 February 2019
Cardiology
Key words: B-type natriuretic peptide, atrial fibrillation, matrix metalloproteinase [more]
Organism: Mouse
Tissue: Heart
SOX17 overexpression sensitizes chemoradiation response in esophageal cancer by transcriptional down-regulation of DNA repair and damage response genes
Journal of Biological Methods (Springer) Taiwan, 18 February 2019
Oncology
Key words: SOX17, Transcription regulation, Resistance, DNA repair, Concurrent chemoradiation therapy, Esophageal cancer [more]
Organism: Human, Mouse
Tissue: Colon, Xenograft Tumor
Pathological State: Cancer
Ultralong circulating choline phosphate liposomal nanomedicines for cascaded chemo-radiotherapy
Biomaterials Science (Royal Society of Chemistry) China, 14 February 2019
Nanomedicine
Key words: Cascaded chemo-radiotherapy, hypoxia-activated therapy, tumor hypoxia, ultralong circulating liposome [more]
Organism: Mouse
Tissue: Allograft Tumor
Pathological State: Cancer
The Accumulation and Effects of Liposomal Doxorubicin in Tissues Treated by Radiofrequency Ablation and Irreversible Electroporation in Liver: In Vivo Experimental Study on Porcine Models
CardioVascular and Interventional Radiology (Springer) Czech Republic, Israel, 13 February 2019
Hepathology
Key words: Liposomal doxorubicin, Radiofrequency ablation, Irreversible electroporation [more]
Organism: Pig
Tissue: Liver
Generation of human iPSCs from fetal prostate fibroblasts HPrF
Stem Cell Research (Elsevier) Czech Republic, 07 February 2019
Stem Cell Research
Key words: induced stem cells, iPSCs, prostate fibroblasts, HPrF [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Multimodal imaging guides surgical management in a preclinical spinal implant infection model
The Journal of Clinical Investigation (American Society of Clinical Investigation) USA, The Netherlands, 07 February 2019
Osteology
Organism: Mouse
Tissue: Spinal Cord
Pathological State: Spine implant infection
Fluorine-Modified Rutaecarpine Exerts Cyclooxygenase-2 Inhibition and Anti-inflammatory Effects in Lungs
Frontiers in Pharmacology (Frontiers Media S.A.) Taiwan, 07 February 2019
Pulmonology
Key words: Fluorine, Rutaecarpine, Cyclooxygenase-2, Anti-inflammatory Effects [more]
Organism: Mouse
Tissue: Whole Organism
Tumoral EHF predicts the efficacy of anti-PD1 therapy in pancreatic ductal adenocarcinoma
Journal of Experimental Medicine (Rockefeller University Press) China, USA, 07 February 2019
Oncology
Key words: EHF, anti-PD1 therapy, adenocarcinoma, pancreas [more]
Organism: Human
Tissue: Pancreas
Pathological State: Cancer
EphB2-dependent signaling promotes neuronal excitotoxicity and inflammation in the acute phase of ischemic stroke
Acta Neuropathologica (Springer) Germany, 05 February 2019
Neuroscience
Key words: EphB2, Ephrin-B2, Excitotoxicity, Inflammation, Ischemic stroke, NMDA [more]
Organism: Mouse
Tissue: Brain
Pathological State: Cerebral Ischemia
HIV-1 and SIV Infection Are Associated with Early Loss of Lung Interstitial CD4+ T Cells and Dissemination of Pulmonary Tuberculosis
Cell Reports (Cell Press) USA, 05 February 2019
Pulmonology
Key words: HIV-1, CD4+ T cells, cell death, tuberculosis, HIV/TB co-infection, lung, BAL [more]
Organism: Mouse
Tissue: Lung, Spleen
Pathological State: HIV Infection, SIV Infection, Tuberculosis
Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade
Immunity (Cell Press) USA, 05 February 2019
Oncology
Key words: cancer immunotherapy IFN-γ activation-induced cell death anti-CTLA-4 anti-PD-1 [more]
Organism: Mouse
Tissue: Allograft Tumor
Pathological State: Cancer
Hypoxic changes to the urothelium as a bystander of end-stage bladder disease
Journal of Pediatric Urology (Elsevier) UK, 05 February 2019
Urology
Key words: Neuropathic bladder, Hypoxia, Hypoxia-inducible factor1 alpha, Obstruction, Regenerative medicine [more]
Organism: Human
Pathological State: Neuropathy
Spatiotemporal Differences in Presentation of CD8 T Cell Epitopes during Hepatitis B Virus Infection
Journal of Virology (American Society for Microbiology) Singapore, Germany, Belgium, UK, 05 February 2019
Virology
Key words: antigen presentation, CD8 T cells, chronic hepatitis B patient, HBV DNA integration, HLA class I, liver, hepatitis B virus [more]
Organism: Human
Tissue: Liver
Pathological State: Hepatitis B Virus Infection
DSE regulates the malignant characters of hepatocellular carcinoma cells by modulating CCL5/CCR1 axis
American Journal of Cancer Research (NCBI) Taiwan, 01 February 2019
Oncology
Key words: Dermatan sulfate, DS epimerase, hepatocellular carcinoma, tumor infiltrated lymphocyte, CCL5 [more]
Organism: Human
Tissue: Liver
Pathological State: Cancer
Pathology of spontaneous and immunotherapy‐induced tumor regression in a murine model of melanoma
Pigment Cell and Melanoma Research (Wiley) USA, 31 January 2019
Oncology
Key words: melanoma, mouse models, B cells, neutrophils, Ly6B.2, histology, tumor regression, NETs [more]
Organism: Mouse
Tissue: Allograft Tumor
Pathological State: Cancer
COPD and asthma therapeutics for supportive treatment in organophosphate poisoning
Clinical Toxicology (Taylor and Francis) Germany, 30 January 2019
Toxicology
Key words: Organophosphate poisoning, nerve agents, PCLS, COPD, asthma [more]
Organism: Rat
Tissue: Lung
Sensory Neuropeptides and their Receptors Participate in Mechano-Regulation of Murine Macrophages
International Journal of Molecular Sciences (MDPI) Germany, 24 January 2019
Immunology
Key words: cyclic stretch, mechan-oregulation, murine macrophages, substance P, alpha-calcitonin gene-related peptide, neurokinin receptor, CGRP receptor, destabilized medial meniscus [more]
Organism: Mouse
Pathological State: Osteoarthritis
Cell Line: Bone Marrow-derived Macrophages
Multiple defects sensitize p53-deficient head and neck cancer cells to the WEE1 kinase inhibition
Molecular Cancer Research (AACR Publications) USA, 24 January 2019
Oncology
Key words: Head and neck cancer, WEE1, TP53, cell cycle, mitosis, replication stress, DNA damage [more]
Organism: Human
Cell Line: Primary fibroblast cells (HFF4), Head and neck cancer cell line UM-SCC-74a
Safe Nanocomposite‐Mediated Efficient Delivery of MicroRNA Plasmids for Autosomal Dominant Polycystic Kidney Disease (ADPKD) Therapy
Advanced Healthcare Materials (Wiley) Taiwan, 23 January 2019
Nanomedicine
Key words: ADPKD, microRNA, MR, I nanoparticles, plasmid DNA [more]
Organism: Mouse
Tissue: Kidney
Pathological State: Kidney Disease
Dynamic changes in intramedullary pressure 72 hours after spinal cord injury
Neural Regeneration Research (Publishing House of Neural Regeneration Research) China, 23 January 2019
Neuroscience
Key words: anesthetized, blood-spinal barrier, conscious, edema, hemorrhage, nerve regeneration, neural regeneration, pathological mechanism, pressure measurement, rabbit, secondary spinal cord injury, telemetry [more]
Organism: Rabbit
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Chronic thromboembolic pulmonary hypertension in Austria and Japan
The Journal of thoracic and cardiovascular surgery (Elsevier) Austria, Japan, 21 January 2019
Cardiology
Key words: Chronic thromboembolic pulmonary hypertension, pulmonary endarterectomy, balloon pulmonary angioplasty,
Transplantation of neural precursors generated from spinal progenitor cells reduces inflammation in spinal cord injury via NF-κB pathway inhibition
Journal of Neuroinflammation (Springer) Czech Republic, USA, 17 January 2019
Stem Cell Research
Key words: NF-κB, p65, Spinal cord injury, Stem cells transplantation, Inflammation, TNF-α, [more]
Organism: Rat
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease
Cancer Cell (Cell Press) Austria, Canada, UK, Australia, 14 January 2019
Oncology
Key words: ERBB, horizontal transmission, MHC class I, receptor tyrosine kinases, STAT3, Tasmanian devil, transmissible cancer, tumor vulnerability, systems biology xenograft [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Probiotic Lactobacillus spp. Act Against Helicobacter pylori-induced Inflammation
Journal of Clinical Medicine (MDPI) Taiwan, 14 January 2019
Microbiology
Key words: Helicobacter pylori, Lactobacillus, probiotic, inflammation [more]
Organism: Mouse
Tissue: Stomach
Pathological State: Helicobacter pylori Infection
Brain-Derived Neurotrophin and TrkB in Head and Neck Squamous Cell Carcinoma
International Journal of Molecular Sciences (MDPI) Austria, 11 January 2019
Oncology
Key words: epithelial–mesenchymal transition, vimentin, cytokeratin, p53 mutation, paraffin embedding, riboprobe [more]
Organism: Human
Tissue: Head and Neck
Pathological State: Cancer
An integrated characterization of contractile, electrophysiological, and structural cardiotoxicity of Sophora tonkinensis Gapnep. in human pluripotent stem cell-derived cardiomyocytes
Stem Cell Research & Therapy (BMC) China, 11 January 2019
Stem Cell Research
Key words: Cardiotoxicity, Sophora tonkinensis, hiPSC-CMs, Cardio-NLCS [more]
Organism: Human
Cell Line: Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)
Clinical significance of c-Met and phospho-c-Met (Tyr1234/1235) in ovarian cancer
Taiwanese Journal of Obstetrics and Gynecology (Elsevier) Taiwan, 09 January 2019
Oncology
Key words: c-Met, phospho-c-Met, Ovarian cancer [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
High-Throughput Synapse-Resolving Two-Photon Fluorescence Microendoscopy for Deep-Brain Volumetric Imaging In Vivo
eLife (eLife Sciences Publications) USA, 03 January 2019
Neuroscience
Key words: two-photon fluorescence microendoscopy, volumetric imaging, Bessel beam, hippocampus, lateral hypothalamus [more]
Organism: Mouse
Tissue: Brain
Genetic labeling reveals temporal and spatial expression pattern of D2 dopamine receptor in rat forebrain
Brain Structure and Function (Springer) China, 02 January 2019
Neuroscience
Key words: Drd2, Knockin rats, Olfactory bulb, Cerebral cortex, Hippocampus [more]
Organism: Mouse, Rat
Tissue: Brain
Abundance of the Organic Anion-transporting Polypeptide OATP4A1 in Early-Stage Colorectal Cancer Patients: Association With Disease Relapse
Applied Immunohistochemistry & Molecular Morphology (Ingentaconnect) Austria, 01 January 2019
Oncology
Key words: OATP4A1, SLCO4A1, automated microscopic imaging system, colorectal cancer, relapse [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Loss of the dystonia gene Thap1 leads to transcriptional deficits that converge on common pathogenic pathways in dystonic syndromes
Human Molecular Genetics (Oxford University Press) USA, 26 December 2018
Neuroscience
Key words: alleles, phenotype, dopamine, signal transduction, transcription, genetic basal ganglia dystonia homeostasis cytoskeleton embryo genes gliosis mice, knockout movement disorders rna, messenger synaptic transmission up-regulation (physiology) zinc fingers cerebellum mice transcription factor agonists antagonists haploinsufficiency nervous system development nestin protein torsion dystonia 6 loss of function mutation [more]
Organism: Mouse
Tissue: Brain
Effects of cylindrospermopsin on cultured immortalized human airway epithelial cells
Chemosphere (Elsevier) Czech Republic, Germany, 22 December 2018
Toxicology
Key words: Cyanobacteria, Cyanotoxin, HBE, Inhalation toxicity, MAPK [more]
Organism: Human
Cell Line: Human bronchial epithelial cell line (HBE) 16HBE14o-cells
Histo-genomics: digital pathology at the forefront of precision medicine
Diagnosis (De Gruyter) Canada, 20 December 2018
Pathology
Spatial mapping of myeloid cells and macrophages by multiplexed tissue staining
Frontiers in Immunology (Frontiers Media S.A.) USA, 14 December 2018
Immunology
Key words: FFPE, immunofluorescence, immunohistochemistry, macrophage, multiplex, myeloid, spatial profiling [more]
Organism: Human
Tissue: Colon, Tonsil
Pathological State: Cancer
Predominant Striatal Input to the Lateral Habenula in Macaques Comes from Striosomes
Current Biology (Cell Press) USA, Japan, 13 December 2018
Neuroscience
Key words: basal ganglia, dopamine, motivation, non-human primate, mood, learning, microstimulation [more]
Organism: Monkey
Tissue: Brain
Melanocyte-specific gene 1 promotes melanoma progression by enhancing the expression of Bcl-2
Oncology Letters (Spandidos Publications) China, 12 December 2018
Oncology
Key words: melanocyte-specific gene 1, melanoma, cell viability, apoptosis, Bcl-2 [more]
Organism: Human
Tissue: Skin
Pathological State: Cancer
The FAK inhibitor BI 853520 inhibits spheroid formation and orthotopic tumor growth in malignant pleural mesothelioma
Journal of Molecular Medicine (Springer) Austria, Germany, Hungary, 11 December 2018
Oncology
Key words: Mesothelioma, Focal adhesion kinase, Tyrosine kinase inhibitor, Angiogenesis, Spheroid formation, Orthotopic xenograft [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Anti-inflammatory compound curcumin and mesenchymal stem cells in the treatment of spinal cord injury in rats.
Acta Neurobiologiae Experimentalis (Nencki Institute of Experimental Biology) Czech Republic, USA, 05 December 2018
Regenerative Medicine
Key words: Spinal cord injury, human mesenchymal stem cells, curcumin, combined therapy, inflammatory response [more]
Organism: Rat
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Cell Line: Human mesenchymal stem cells (hMSCs)
The natural polyphenol curcumin induces apoptosis by suppressing STAT3 signaling in esophageal squamous cell carcinoma
Journal of Experimental & Clinical Cancer Research (Springer) China, 05 December 2018
Oncology
Key words: Curcumin, STAT3, Esophageal squamous cell carcinoma, Apoptosis, PDX model [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
CXCL5 as regulator of neutrophil function in cutaneous melanoma
Journal of Investigative Dermatology (Elsevier) Austria, Germany, Spain, 04 December 2018
Oncology, Dermatology
Organism: Mouse
Tissue: Lung, Xenograft Tumor
Pathological State: Cancer
Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression
The Journal of Clinical Investigation (American Society for Clinical Investigation) USA, China, 04 December 2018
Oncology
Key words: Genetics, Oncology, Prostate cancer [more]
Organism: Human
Tissue: Prostate
Pathological State: Cancer
Extracellular vesicles from mature dendritic cells (DC) differentiate monocytes into immature DC
Life Science () Germany, Austria, 03 December 2018
Immunology
Key words: Medical Research, Immunology [more]
Organism: Human, Mouse
Cell Line: Monocyte-derived dentritic cells
Elevated Serum Interleukin-8 Level Correlates with Cancer-Related Cachexia and Sarcopenia: An Indicator for Pancreatic Cancer Outcomes
Journal of Clinical Medicine (MDPI) Taiwan, 01 December 2018
Oncology
Key words: pancreatic cancer, cancer cachexia, sarcopenia, interleukin (IL)-1β, IL-6, IL-8, tumor necrosis factor (TNF)-α [more]
Organism: Human
Tissue: Pancreas
Pathological State: Cancer