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Customer Publications (A total of 2116 papers published)

1801
PI3K/AKT Signaling Is Essential for Communication between Tissue-Infiltrating Mast Cells, Macrophages, and Epithelial Cells in Colitis-Induced Cancer

Mohammad W Khan, Ali Keshavarzian, Elias Gounaris, Joshua E Melson, Eric C Cheon, Nichole R Blatner, Zongmin E Chen, Fu-Nien Tsai, Goo Lee, Hyunji Ryu, Terrence A Barrett, David J Bentrem, Philipp Beckhove, Khashayarsha Khazaie

Clinical Cancer Research (AACR Publications) USA, Germany, 13 March 2013

Oncology

Key words: Colitis, dysplasia, colorectal cancer, colonic submucosa, phosphoinositide 3-kinase

Organism: Human

Tissue: Colon

Pathological State: Colitis, Cancer

1802
Tumor STAT1 Transcription Factor Activity Enhances Breast Tumor Growth and Immune Suppression Mediated by Myeloid-derived Suppressor Cells

Laura M Hix, John Karavitis, Mohammad W Khan, Yihui H Shi, Khashayarsha Khazaie, Ming Zhang

Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) USA, 13 March 2013

Oncology

Key words: Breast Cancer, immunosuppression, signal transduction, T Cell, tumor immunology, MDSC, STAT1, mouse model of breast cancer

Organism: Human, Mouse

Tissue: Breast

Pathological State: Cancer

1803
Type III Secretion of ExoU Is Critical during Early Pseudomonas aeruginosa Pneumonia

Heather A Howell, Latania K Logan, Alan R Hauser

mBio (ASM) USA, 12 March 2013

Pulmonology

Key words: Eukaryotic cells, Many Gram-negative bacteria, Pseudomonas aeruginosa

Organism: Mouse

Tissue: Lung

Pathological State: Pneumonia, Pseudomonas Infection

1804
Rapid dramatic alterations to the tumor microstructure in pancreatic cancer following irreversible electroporation ablation

Zhuoli Zhang, Weiguo Li, Daniel Procissi, Patrick Tyler, Reed A Omary, Andrew C Larson

Nanomedicine (Future Medicine) USA, 12 March 2013

Nanomedicine

Key words: Immunohistochemistry apoptosis, IRE-treated tumors

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

1805
Late Infusion of Cloned Marrow Fibroblasts Stimulates Endogenous Recovery from Radiation-Induced Lung Injury

Mineo Iwata, David K Madtes, Kraig Abrams, Wayne J E Lamm, Robb W Glenny, Richard A Nash, Aravind Ramakrishnan, Beverly Torok-Storb

PLoS One (PLOS) USA, 08 March 2013

Regenerative Medicine

Key words: Dogs, pulmonary imaging, computed axial tomography, stem cells, fibroblasts, endothelial cells, pulmonary function, reverse transcriptase-polymerase chain reaction

Organism: Dog

Tissue: Lung

Pathological State: Radiation-induced lung injury

1806
Quantitative measurement of the androgen receptor in prepuces of boys with and without hypospadias

Renate Pichler, Gabriel Djedovic, Helmut Klocker, Isabel Heidegger, Alexander Strasak, Wolfgang Loidl, Jasmin Bektic, Viktor Skradski, Wolfgang Horninger, Josef Oswald

BJU International (Wiley) Austria, 07 March 2013

Endocrinology

Key words: Hypospadias, aetiology, androgen receptor, genetics, signalling

Organism: Human

Tissue: Prostate

Pathological State: Hypospadias

1807
FRI0270 Development of systemic lupus-like disease in regulatory T cells (TREG)-deficient scurfy mice

G Stummvoll, X Wei, H Leiss, B Niederreiter, B Heckmann, W Ulrich, A Enk, J Smolen, E Hadaschik

Annals of the Rheumatic Diseases (BMJ Journals) Austria, Germany, 01 March 2013

Rheumatology

Key words: Lupus, T cells

Organism: Mouse

Tissue: Skin

Pathological State: Lupus

1808
The 10th International Congress on SLE

McMahon M, Skaggs B, Grossman J, Sahakian L, FitzGerald J, Lourenco E, Ragavendra N, Charles-Schoeman C, Gorn A, Karpuzas G, Taylor M, Watson K, Weisman M, Wallace D, Hahn BH

Lupus (SAGE Journals) USA, 01 March 2013

Rheumatology

Key words: Pro-inflammatory HDL, subclinical atherosclerosis, NGAL (lipocalin-2)

1809
Hyaluronan enhances bone marrow cell therapy for myocardial repair after infarction

CH Chen, SS Wang, EIH Wei, TY Chu, PCH Hsieh

Molecular Therapy (Cell Press) Taiwan, 01 March 2013

Cardiology

Organism: Rat

Tissue: Heart

Pathological State: Myocardial Infarction

1810
Human Umbilical Vein Endothelial Cells Protect Against Hypoxic-Ischemic Damage in Neonatal Brain via Stromal Cell-derived Factor 1/C-X-C Chemokine Receptor Type 4

Chia-Ching Wu, Yi-Chi Chen, Ying-Chao Chang, Lan-Wan Wang, Yung-Chieh Lin, Yi-Lun Chiang, Chien-Jung Ho, Chao-Ching Huang

Stroke (AHA Journals) Taiwan, 28 February 2013

Neuroscience

Key words: Human umbilical vein endothelial cell, neonatal brain, neurovascular unit, SDF-1/CXCR4

Organism: Rat, Human

Tissue: Brain

Pathological State: Cerebral ischemia

Cell Line: HUVECs (Human umbilical vein endothelial cells)

1811
Noninvasive and Targeted Gene Delivery into the Brain Using Microbubble-Facilitated Focused Ultrasound

Po-Hung Hsu, Kuo-Chen Wei, Chiung-Yin Huang, Chih-Jen Wen, Tzu-Chen Yen, Chao-Lin Liu, Ya-Tin Lin, Jin-Chung Chen, Chia-Rui Shen, Hao-Li Liu

PLoS One (PLOS) Taiwan, 27 February 2013

Nanomedicine

Key words: Viral vectors, magnetic resonance imaging , central nervous system, astrocytes, gene delivery, gene expression, acoustics, neurons

Organism: Mouse

Tissue: Brain

1812
Abatacept (CTLA-4IG) treatment reduces the migratory capacity of monocytes in patients with rheumatoid arthritis

M Bonelli, E Ferner, L Göschl, S Blüml, A Hladik, T Karonitsch, H P Kiener, R Byrne, B Niederreiter, C W Steiner, E Rath, M Bergmann, J S Smolen, C Scheinecker

Arthritis & Rheumatology (Wiley) Austria, 25 February 2013

Rheumatology

Key words: Antigen-presenting cells, CTLA-4Ig, Peripheral blood mononuclear cells

Organism: Human

Pathological State: Rheumatoid Arthritis

Cell Line: PBMCs

1813
Tumor necrosis factor–inhibiting therapy preferentially targets bone destruction but not synovial inflammation in a tumor necrosis factor–driven model of rheumatoid arthritis

Nikolaus B Binder, Antonia Puchner, Birgit Niederreiter, Silvia Hayer, Harald Leiss, Stephan Blüml, Roman Kreindl, Josef S Smolen, Kurt Redlich

Arthritis & Rheumatology (Wiley) Austria, USA, 25 February 2013

Rheumatology

Key words: Tumor necrosis factor, osteoclastogenesis in vitro, cell–derived monocytes

Organism: Mouse

Tissue: Joint Tissue, Bone

Pathological State: Rheumatoid Arthritis

1814
Adipose stromal cells primed with hypoxia and inflammation enhance cardiomyocyte proliferation rate in vitro through STAT3 and Erk1/2

Ewa Przybyt, Guido Krenning, Marja GL Brinker, Martin C Harmsen

Journal of Translational Medicine (Springer) The Netherlands, 13 February 2013

Cardiology

Key words: hl-1 cardiomyocyte, hl-1 cell, jak stat inhibitor, cardiomyocyte proliferation, cardiomyocyte proliferation, cardiomyocyte proliferation, cardiomyocyte proliferation, cardiomyocyte proliferation, cardiomyocyte proliferation, cardiomyocyte proliferation, cardiomyocyte proliferation, cardiomyocyte proliferation

Organism: Human

Cell Line: Cardiomyocytes

1815
Automated REcognition of Tissue-associated Erythrocytes (ARETE)—a new tool in tissue cytometry

Andreas Heindl, Alexander K Seewald, Theresia Thalhammer, Giovanna Bises, Martin Schepelmann, Hana Uhrova, Sabine Dekan, Ildiko Mesteri, Radu Rogojanu, Isabella Ellinger

Cytometry Part A (Wiley) Austria, 11 February 2013

Medical Image Analysis

Key words: Erythrocytes, immunofluorescence microscopy, autofluorescence, tissue cytometry, automated image analysis, boosted decision trees of Haar-like features, machine learning, placenta, colorectal cancer

Organism: Human

Tissue: Colon

1816
Characterization of Transcriptional Changes in ERG Rearrangement-Positive Prostate Cancer Identifies the Regulation of Metabolic Sensors Such as Neuropeptide Y

Petra Massoner, Karl G Kugler, Karin Unterberger, Ruprecht Kuner, Laurin A J Mueller, Maria Fälth, Georg Schäfer, Christof Seifarth, Simone Ecker,Irmgard Verdorfer, Armin Graber, Holger Sültmann, Helmut Klocker

PLoS One (PLOS) Austria, Germany, 04 February 2013

Oncology

Key words: Prostate cancer, gene expression, meta-analysis, prostate gland, gene regulation, microarrays, cell metabolism, glucose metabolism

Organism: Human

Tissue: Prostate

Pathological State: Cancer

1817
Circulating Metastasis Promoting Protein S100A4 in Idiopathic Inflammatory Myopathies

L Pleštilová, O Pecha, H Mann, LA Cerezo, J Vencovský, L Šenolt

Annals of the Rheumatic Diseases (BMJ Journals) Czech Republic, 02 February 2013

Rheumatology

Key words: Protein S100A4, rheumatoid arthritis, psoriasis

1818
Oestrogens improve human pancreatic islet transplantation in a mouse model of insulin deficient diabetes

S Liu, G Kilic, M S Meyers, G Navarro, Y Wang, J Oberholzer, F Mauvais-Jarvis

Diabetologia (Springer) USA, China, 01 February 2013

Endocrinology

Key words: Ffunctional vessel density, human alpha cell, human islet graft, beta cell regeneration, beta cell apoptosis, islet transplantation, islet yield, sirolimus, islet engraftment, apoptotic beta cell, cultured human islet, beta cell proliferation, tacrolimus, mouse islet, insulin independence

Organism: Mouse

Tissue: Kidney

Pathological State: Diabetes

1819
Long course hyperbaric oxygen stimulates neurogenesis and attenuates inflammation after ischemic stroke

YS Lee, CC Chio, CP Chang, LC Wang, PM Chiang, KC Niu, KJ Tsai

Mediators of Inflammation (Hindawi Publishing Corporation) Taiwan, 15 January 2013

Neuroscience

Organism: Rat

Tissue: Brain

Pathological State: Stroke

1820
Cystathionine γ-Lyase Protects against Renal Ischemia/Reperfusion by Modulating Oxidative Stress

Eelke M Bos, Rui Wang, Pauline M Snijder, Miriam Boersema, Jeffrey Damman, Ming Fu, Jill Moser, Jan-Luuk Hillebrands, Rutger J Ploeg, Guangdong Yang, Henri GD Leuvenin, Harry van Goor

Journal of The American Society of Nephrology (JASN) Canada, UK, The Netherlands, 02 January 2013

Nephrology

Key words: Cystathionine γ-lyase, tubulointerstitium, glomeruli, renal ischemia

1821
Tumor-specific expression of organic anion-transporting polypeptides: transporters as novel targets for cancer therapy

Veronika Buxhofer-Ausch, Lena Secky, Katrin Wlcek, Martin Svoboda, Valentinos Kounnis, Evangelos Briasoulis, Andreas G Tzakos, Walter Jaeger, and Theresia Thalhammer

Journal of drug delivery (Hindawi Publishing Corporation) Austria, Switzerland, Greece, 01 January 2013

Oncology

Organism: Human

Tissue: Pancreas

Pathological State: Cancer

1822
The role of glucocorticoid receptors in dexamethasone-induced apoptosis of neuroprogenitor cells in the hippocampus of rat pups

CI Sze, YC Lin, YJ Lin, TH Hsieh, YM Kuo, CH Lin

Mediators of Inflammation (Hindawi Publishing Corporation) Taiwan, 01 January 2013

Neuroscience

Organism: Rat

Tissue: Brain

1823
MAGNESIUM AND ZINC INFLUENCE ON FEMALE GENITAL TRACT IN EXPERIMENTAL INDUCED DIABETES MELLITUS.

Galeş, Cristina, Nechifor, M, Stoica, B, Stan, C I, Zamfir, Carmen Lãcrãmioara

Romanian Journal of Functional and Clinical, Macro- and Microscopical Anatomy and of Anthropology () Romania, 01 January 2013

Reproductive Medicine

Pathological State: Diabetes

1824
The effect of pioglitazone on non-pregnant female genital tract in experimental diabetes mellitus

C Gales, C Zamfir, B Stoica, M Nechifor

The Medical-Surgical  Journal (revmedchir) Romania, 01 January 2013

Reproductive Medicine

Key words: DIABETES MELLITUS, STREPTOZOTOCIN, PIOGLITAZONE, OVARY

Pathological State: Diabetes

1825
Tracing Conidial Fate and Measuring Host Cell Antifungal Activity Using a Reporter of Microbial Viability in the Lung

Anupam Jhingran, Katrina B Mar, Debra K Kumasaka, Sue E Knoblaugh, Lisa Y Ngo, Brahm H Segal, Yoichiro Iwakura, Clifford A Lowell, Jessica A Hamerman, Xin Lin, Tobias M Hohl

Cell Reports (Cell Press) USA, Japan, 27 December 2012

Virology

Key words: FLARE conidia, C-type lectin receptor, leukocyte-fungal cell

Organism: Mouse

Tissue: Lung

Pathological State: Fungal Infection

1826
Comprehensive morphometric analysis of mononuclear cell infiltration during experimental renal allograft rejection

Ute Hoffmann, Tobias Bergler, Bettina Jung, Andreas Steege, Claudia Pace, Petra Rümmele, Stephan Reinhold, Bernd Krüger, Bernhard K Krämer, Bernhard Banas

Transplant Immunology (Elsevier) Germany, 23 December 2012

Transplantation Medicine

Key words: B-cells, different analysis methods, experimental renal allograft rejection, macrophages, T-cells

Organism: Rat

Tissue: Kidney

Pathological State: Allogeneic Transplantation

1827
Ectopic Pregnancy-Derived Human Trophoblastic Stem Cells Regenerate Dopaminergic Nigrostriatal Pathway to Treat Parkinsonian Rats

Tony Tung-Yin Lee, Cheng-Fang Tsai, Tsung-Hsun Hsieh, Jia-Jin Jason Chen, Yu-Chih Wang, Mi-Chun Kao, Ruey-Meei Wu, Sher Singh, Eing-Mei Tsai, Jau-Nan Lee

PLoS One (PLOS) Taiwan, 21 December 2012

Stem Cell Research

Key words: Neurons, pluripotency, flow cytometry, pregnancy, dopamine, dopaminergics, rats, cell differentiation

Organism: Rat

Tissue: Brain

Pathological State: Parkinson's Disease

1828
Enhancement of the Immunogenicity and Protective Efficacy of a Mucosal Influenza Subunit Vaccine by the Saponin Adjuvant GPI-0100

Heng Liu, Harshad P Patil, Jacqueline de Vries-Idema, Jan Wilschut, Anke Huckriede

PLoS One (PLOS) The Netherlands, 17 December 2012

Immunology

Key words: Vaccines, immunologic adjuvants, influenza, immune response, antibodies, antibody response, influenza viruses, viral vaccines

Organism: Mouse

Tissue: Lung

Pathological State: Influenza Infection

1829
Spatiotemporal evolution of early innate immune responses triggered by neural stem cell grafting

Kristien Reekmans, Nathalie De Vocht, Jelle Praet, Erik Fransen, Debbie Le Blon, Chloé Hoornaert, Jasmijn Daans, Herman Goossens, Annemie Van der Linden, Zwi Berneman, Peter Ponsaerts

Stem Cell Research & Therapy (BMC) Belgium, 14 December 2012

Stem Cell Research

Key words: Anti-APC (Adenomatous polyposis coli protein) antibody, central nervous system, enhanced green fluorescent protein, neuronal nuclei

Organism: Mouse

Tissue: Brain

1830
CHC promotes tumor growth and angiogenesis through regulation of HIF-1α and VEGF signaling

Kuo-Hua Tung, Cheng-Wei Lin, Chun-Chen Kuo, Li-Tzu Li, Ya-Hsun Kuo, Chung-Wu Lin, Han-Chung Wu

Cancer Letters (Elsevier) Taiwan, 07 December 2012

Oncology

Key words: Pancreatic cancer, monoclonal antibody, clathrin heavy chain, HIF-1a, angiogenesis

Organism: Human

Tissue: Pancreas

Pathological State: Cancer

1831
Depletion of tristetraprolin in breast cancer cells increases interleukin-16 expression and promotes tumor infiltration with monocytes/macrophages

Larissa Milke, Kathrin Schulz, Andreas Weigert, Weixiao Sha, Tobias Schmid, Bernhard Brüne

Carcinogenesis (Oxford University Press) Germany, 04 December 2012

Oncology

Key words: RNA-binding protein tristetraprolin, macrophages, interleukin-16, granulocyte macrophage-colony

1832
Stem Cell-Like Differentiation Potentials of Endometrial Side Population Cells as Revealed by a Newly Developed In Vivo Endometrial Stem Cell Assay

Kaoru Miyazaki, Tetsuo Maruyama , Hirotaka Masuda, Akiko Yamasaki, Sayaka Uchida, Hideyuki Oda, Hiroshi Uchida, Yasunori Yoshimura

PLoS One (PLOS) Japan, 04 December 2012

Stem Cell Research

Key words: Stem cells, cell differentiation, kidneys, stem cell transplantation, endometrium, flow cytometry, stem cell niche, renal transplantation

Organism: Mouse

Tissue: Kidney

1833
Towards the Automated Detection and Characterization of Osteoclasts in Microscopic Images

Andreas Heindl, Martin Schepelmann, Rupert Ecker, Peter Pietschmann, Isabella Ellinger, Alexander K Seewald, Theresia Thalhammer

Principles of Osteoimmunology (Springer) Austria, 01 December 2012

Medical Image Analysis

Key words: Giant Cell Tumor, Joint Photographic Expert Group, Portable Network Graphic, Biological Expert, Osteoclast Culture

Organism: Human

Cell Line: Osteoclasts

1834
Crypts detection in microscopic images using hierarchical structures

Cristian Smochina, Vasile Manta, Walter Kropatsch

Pattern Recognition Letters (Elsevier) Romania, Austria, 29 November 2012

Pathology

Key words: Crypt segmentation, morphological hierarchy, morphological pyramid, biomedical imaging, pathology, microscopy

Organism: Human

Tissue: Colon

1835
The in Vivo Imaging Platform for Cell Tracking in the Stem Cell-Induced Immune Tolerance to Vascularized Composite Allotransplantation: 1756

CJ Wen, HY Cheng, LY Shih, CF Lin, FC Wei

Transplantation (Wolters Kluwer) China, 27 November 2012

Microscopy

Organism: Rat

Tissue: Whole Organism

Pathological State: Allogeneic Transplantation

1836
Proteinuria triggers renal lymphangiogenesis prior to the development of interstitial fibrosis

Saleh Yazdani , Fariba Poosti, Andrea B Kramer, Katarina Mirković, Arjan J Kwakernaak, Menno Hovingh, Maartje C J Slagman, Klaas A Sjollema, Martin H de Borst, Gerjan Navis, Harry van Goor, Jacob van den Born

PLoS One (PLOS) The Netherlands, 26 November 2012

Nephrology

Key words: Lymph , Proteinuria , Kidneys , Fibrosis , Macrophages , Fibroblasts , Epithelial cells , Collagens

Organism: Rat

Tissue: Kidney

Pathological State: Renal Fibrosis

1837
Epithelial Cell Adhesion Molecule Regulates Tumor Initiation and Tumorigenesis via Activating Reprogramming Factors and Epithelial-Mesenchymal Transition Gene Expression in Colon Cancer

Cheng-Wei Lin, Mei-Yin Liao, Wen-Wei Lin, Yi-Ping Wang, Tung-Yin Lu, Han-Chung Wu

Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) Taiwan, 16 November 2012

Oncology

Key words: Cancer Biology, Cancer Stem Cells, Cancer Tumor, Promoter Oncogene, Stem Cells EpCAM, Epithelial-Mesenchymal Transition, Reprogramming Factor Tumor-initiating, Cells Tumorsphere

Organism: Human

Tissue: Colon

Pathological State: Cancer

1838
Photodynamic Control of Bioactivity in a Nanofiber Matrix

Shantanu Sur, John B Matson, Matthew J Webber, Christina J Newcomb, Samuel I Stupp

ACS NANO (ACS Publications) USA, 15 November 2012

Nanomedicine

Key words: Supramolecular nanofibers, cell morphological analysis, nitrobenzyl, projected cell area, photodegradable, RGDS epitope

Organism: Mouse

Cell Line: NIH 3T3 mouse embryonic fibroblasts

1839
Valproic Acid Induces Cutaneous Wound Healing In Vivo and Enhances Keratinocyte Motility

Soung-Hoon Lee, Muhammad Zahoor, Jae-Kwan Hwang, Do Sik Min, Kang-Yell Choi

PLoS One (PLOS) South Korea, 07 November 2012

Dermatology

Key words: Wound healing, keratinocytes, collagens, keratins, ERK signaling cascade, Wnt signaling cascade, immunohistochemical analysis, beta-catenin signaling

Organism: Mouse

Tissue: Skin

Pathological State: Cutaneous wound

1840
SOCS-3 is downregulated in progressive CKD patients and regulates proliferation in human renal proximal tubule cells in a STAT1/3 independent manner

H Neuwirt, IE Eder, M Puhr, M Rudnicki

Laboratory Investigation (Nature) Austria, 29 October 2012

Physiology

Key words: Cell proliferation, Cell signalling, Chronic kidney disease

Organism: Human

Tissue: Kidney

Pathological State: Kidney Disease

1841
Modulation of STAT-3 in rheumatoid synovial T cells suppresses Th17 differentiation and increases the proportion of Treg cells

Ji Hyeon Ju, Yu-Jung Heo, Mi-La Cho, Joo-Yeon Jhun, Jin-Sil Park, Seon-Yeong Lee, Hye-Jwa Oh, Su-Jin Moon, Seung-Ki Kwok, Kyung-Su Park, Sung-Hwan Park, Ho-Youn Kim

Arthritis & Rheumatology (Wiley) South Korea, 27 October 2012

Rheumatology

Key words: STAT-3–mediated regulation, rheumatoid arthritis, CD4+ T cells, synovial fluid

Organism: Human

Pathological State: Rheumatoid Arthritis

Cell Line: PBMCs

1842
Bone regeneration with low dose BMP-2 amplified by biomimetic supramolecular nanofibers within collagen scaffolds

Sungsoo S Lee, Brian J Huang, Stuart R Kaltz, Shantanu Sur, Christina J Newcomb, Stuart R Stock, Ramille N Shah, Samuel I Stupp

Biomaterials (Elsevier) USA, 22 October 2012

Regenerative Medicine

Key words: Peptide amphiphile, heparin, heparan sulfate, BMP-2 (bone morphogenetic protein-2), regenerative medicine, bone regeneration

Organism: Rat

Tissue: Bone

1843
Establishing an allergic eczema model employing recombinant house dust mite allergens Der p 1 and Der p 2 in BALB/c mice

Krisztina Szalai, Tamara Kopp, Anna Lukschal, Caroline Stremnitzer, Julia Wallmann, Philipp Starkl, Luc Vander Elst, Jean-Marie Saint-Remy, Isabella Pali-Schöll, Erika Jensen-Jarolim

Experimental Dermatology (Wiley) Austria, Belgium, 15 October 2012

Dermatology

Key words: Allergic eczema, atopic eczema, Der p1 and Der p 2, house dust mite, protease activity, recombinant allergens

Organism: Mouse

Tissue: Skin

Pathological State: Eczema

1844
PDGFR blockade is a rational and effective therapy for NPM-ALK–driven lymphomas

Daniela Laimer, Helmut Dolznig, Karoline Kollmann, Paul W Vesely, Michaela Schlederer, Olaf Merkel, Ana-Iris Schiefer, Melanie R Hassler, Susi Heider, Lena Amenitsch, Christiane Thallinger, Philipp B Staber, Ingrid Simonitsch-Klupp, Matthias Artaker, Sabine Lagger, Suzanne D Turner, Stefano Pileri, Pier Paolo Piccaluga, Peter Valent, Katia Messana, Indira Landra, Thomas Weichhart, Sylvia Knapp, Medhat Shehata, Maria Todaro, Veronika Sexl, Gerald Höfler, Roberto Piva, Enzo Medico, Bruce A Ruggeri, Mangeng Cheng, Robert Eferl, Gerda Egger, Josef M Penninger, Ulrich Jaeger, Richard Moriggl, Giorgio Inghirami and Lukas Kenner

Nature Medicine (Nature) Austria, USA, UK, Italy, 14 October 2012

Oncology

Key words: Mechanism of action, Non-hodgkin lymphoma, Therapeutics

Organism: Human

Tissue: Lymphoid Tissue

Pathological State: Cancer

1845
Prospero Homeobox 1 Promotes Epithelial–Mesenchymal Transition in Colon Cancer Cells by Inhibiting E-cadherin via miR-9

Mei-Hsuan Lu, Chao-Cheng Huang, Mei-Ren Pan, Hong-Hwa Chen, Wen-Chun Hung

Clinical Cancer Research (AACR Publications) Taiwan, 08 October 2012

Oncology

Key words: Prospero homeobox 1, matrix metalloproteinase activity, epithelial–mesenchymal transition

Organism: Human

Tissue: Colon

Pathological State: Cancer

1846
Investigation of the Relationship Between Prostate Cancer and MSMB and NCOA4 Genetic Variants and Protein Expression

Liesel M FitzGerald, Xiaotun Zhang, Suzanne Kolb, Erika M Kwon, Ying Ching Liew, Antonio Hurtado-Coll, Beatrice S Knudsen, Elaine A Ostrander, Janet L Stanford

Human Mutation (Wiley) USA, Canada, 04 October 2012

Oncology

Key words: Prostate cancer, MSMB, PSP94, NCOA4

Organism: Human

Tissue: Prostate

Pathological State: Cancer

1847
Hepatology AASLD Abstracts

Hepatology (Wiley) UK, 01 October 2012

Hepathology

1848
γ-secretase inhibitors prevent overgrowth of transplanted neural progenitors derived from human-induced pluripotent stem cells

A Ogura, A Morizane, Y Nakajima, S Miyamoto, and J Takahashi

Stem Cells and Development (Mary Ann Liebert Inc.) Japan, 28 September 2012

Regenerative Medicine

Organism: Mouse

Tissue: Brain

1849
Brief Report: Amelioration of collagen-induced arthritis in mice by lentivirus-mediated silencing of microRNA-223

Yuan-Tsung Li, Shih-Yao Chen, Chrong-Reen Wang, Ming-Fei Liu, Chi-Chen Lin, I-Ming Jou, Ai-Li Shiau, Chao-Liang Wu

Arthritis & Rheumatology (Wiley) Taiwan, 27 September 2012

Rheumatology

Key words: MicroRNA, MiRNA-223 , rheumatoid arthritis, osteoarthritis, reverse transcriptase–polymerase chain reaction

Organism: Mouse

Tissue: Joint Tissue, Bone

Pathological State: Rheumatoid Arthritis

1850
A global downregulation of microRNAs occurs in human quiescent satellite cells during myogenesis

Merel Koning, Paul MN Werker, Marja JA van Luyn, Guido Krenning, Martin C Harmsen

Differentiation (Elsevier) The Netherlands, 26 September 2012

Developmental Biology

Key words: Satellite cells, Skeletal muscle, Quiescence, MicroRNA, MicroRNA microarray

Organism: Human

Tissue: Muscle

1851
Male Microchimerism in the Human Female Brain

William F N Chan , Cécile Gurnot, Thomas J Montine, Joshua A Sonnen, Katherine A Guthrie, J Lee Nelson

PLoS One (PLOS) USA, 26 September 2012

Neuroscience

Key words: Alzheimer disease, brain diseases, pregnancy, natural history of disease, amygdala, frontal lobe, washington, Y chromosomes

Organism: Mouse

Tissue: Brain

1852
Improved assessment of frozen/thawed mouse spermatozoa using fluorescence microscopy

AK Diercks, HF Bürgers, A Schwab, J Schenkel

Journal of veterinary science (Kamje Press) Germany, 20 September 2012

Reproductive Medicine

Key words: cryopreservation, fluorescence microscopy, genetically modified (GM) mice, membrane integrity, 3Rs

1853
Comparative Secretome Analyses Using a Hollow Fiber Culture System with Label-Free Quantitative Proteomics Indicates the Influence of PARK7 on Cell Proliferation and Migration/Invasion in Lung Adenocarcinoma

Ying-Hua Chang , Shu-Hui Lee, Hua-Chien Chang, Yau-Lin Tseng, Wu-Wei La, Chen-Chung Lia, Yeou-Guang Tsa, and Pao-Chi Liao

Journal of Proteome Research (ACS Publications) Taiwan, 17 September 2012

Oncology

Key words: Hollow fiber culture system, label-free quantitative proteomics, PARK7, cancer metastasis

Organism: Human

Tissue: Lung

Pathological State: Cancer

1854
Honey bee (Apis mellifera) venom induces AIM2 inflammasome activation in human keratinocytes

Y Dombrowski, M Peric, S Koglin, N Kaymakanov, V Schmezer, M Reinholz, T Ruzicka andJ Schauber

Allergy (Wiley) Germany, 13 September 2012

Allergy Research

Key words: AIM2 inflammasome, allergic reaction, cytosolic DNA, honey bee venom, keratinocytes

Organism: Human

Cell Line: Epidermal keratinocytes

1855
Prevention of preneoplastic lesions by dietary vitamin D in a mouse model of colorectal carcinogenesis

Doris Maria Hummel, Ursula Thiem, Julia Höbaus, Ildiko Mesteri, Lukas Gober, Caroline Stremnitzer, João Graça, Barbara Obermayer-Pietsch, Enikö Kallay

The Journal of Steroid Biochemistry and Molecular Biology (Elsevier) Austria, UK, 11 September 2012

Oncology

Key words: Vitamin D, colorectal cancer, dysplasia, chemoprevention, cyp24a1, cyp27b1

Organism: Mouse

Tissue: Colon

1856
Quantitative Immunofluorescence Reveals the Signature of Active B-cell Receptor Signaling in Diffuse Large B-cell Lymphoma

Agata M Bogusz, Richard HG Baxter, Treeve Currie, Papiya Sinha, Aliyah R Sohani, Jeffery L Kutok, Scott J Rodig

Clinical Cancer Research (AACR Publications) USA, 10 September 2012

Oncology

Key words: B-cell receptor, diffuse large B-cell lymphomas, DLBCL pathogenesis

Organism: Human

Tissue: Lymphoid Tissue

Pathological State: Cancer

1857
Isolation and phenotypic characterisation of stem cells from late stage osteoarthritic mesenchymal tissues

Labusca, Luminita, Zugun-Eloae, Florin, Shaw, Georgina, Botez, Paul, Barry, Frank, Mashayekhi, Kaveh

Current stem cell research and Therapy (Ingentaconnect) Romania, 01 September 2012

Stem Cell Research

Key words: Chondrogenesis, mesenchymal stem cells, osteoarthritis, regenerative medicine.

Organism: Human

Tissue: Bone, Adipose Tissue

Pathological State: Osteoarthritis

1858
The use of a tumor metastasis targeting peptide to deliver doxorubicin-containing liposomes to highly metastatic cancer

Zhaohui Wang, Yang Yu, Wenbing Dai, Jingkai Lu, Jingrong Cui, Hounan Wu, Lan Yuan, Hua Zhang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Qiang Zhang

Biomaterials (Elsevier) China, 30 August 2012

Nanomedicine

Key words: Highly metastatic tumor, targeting, nanomedicine, liposomes, delivery

Organism: Mouse

Tissue: Breast, Xenograft Tumor

Pathological State: Cancer

1859
Neuron-Specific Prolyl-4-Hydroxylase Domain 2 Knockout Reduces Brain Injury After Transient Cerebral Ischemia

NS Prolyl, H Domain

Stroke (AHA Journals) Germany, 28 August 2012

Neuroscience

Key words: HIF-1, hypoxia, neuroprotection, PHD, stroke

Organism: Mouse

Tissue: Brain

Pathological State: Cerebral Ischemia

1860
Epithelial-to-Mesenchymal Transition Leads to Docetaxel Resistance in Prostate Cancer and Is Mediated by Reduced Expression of miR-200c and miR-205

Martin Puhr, Julia Hoefer, Georg Schäfer, Holger HH Erb, Su Jung Oh, Helmut Klocker, Isabel Heidegger, Hannes Neuwirt, Zoran Culig

The American Journal of Pathology (Elsevier) China, 11 August 2012

Oncology

Key words: Docetaxel, (miR)-200c, miR-205, E-cadherin, Systemic polychemotherapy

Organism: Human

Tissue: Prostate

Pathological State: Cancer

1861
Quantitative and phenotypic analysis of mesenchymal stromal cell graft survival and recognition by microglia and astrocytes in mouse brain

Nathalie De Vocht,Dan Lin, Jelle Praet, Chloé Hoornaert, Kristien Reekmans, Debbie Le Blon, Jasmijn Daans, Patrick Pauwels, Herman Goossens, Niel Hens, Zwi Berneman, Annemie Van der Linden, Peter Ponsaert

Immunobiology (Elsevier) Belgium, 09 August 2012

Immunology

Key words: Astrocytes, brain, cell transplantation, mesenchymal stromal cell, microglia

Organism: Mouse

Tissue: Brain

1862
A mouse model to identify cooperating signaling pathways in cancer

Monica Musteanu, Leander Blaas, Rainer Zenz, Jasmin Svinka, Thomas Hoffmann, Beatrice Grabner, Daniel Schramek, Hans-Peter Kantner, Mathias Müller, Thomas Kolbe, Thomas Rülicke, Richard Moriggl, Lukas Kenner, Dagmar Stoiber, Josef Martin Penninger, Helmut Popper, Emilio Casanova and Robert Eferl

Nature Methods (Nature) Austria, Spain, 05 August 2012

Oncology

Key words: animal disease models, Cancer genetics, Mouse

Organism: Mouse

Tissue: Lung, Pancreas, Skin

Pathological State: Cancer

1863
Activation of Notch Signaling During Ex Vivo Expansion Maintains Donor Muscle Cell Engraftment

Maura H Parker, Carol Loretz, Ashlee E Tyler, William J Duddy, John K Hall, Bradley B Olwin, Irwin D Bernstein, Rainer Storb, Stephen J Tapscott

Stem Cells (Wiley) USA, 03 August 2012

Stem Cell Research

Key words: Striated muscle, satellite cells, regeneration, primary cell culture, notch ligand, cell transplantation

Organism: Mouse

Tissue: Muscle

1864
Coordinated roles of ST3Gal-VI and ST3Gal-IV sialyltransferases in the synthesis of selectin ligands

Won Ho Yang, Claudia Nussbaum, Prabhjit K Grewal, Jamey D Marth, Markus Sperandio

Blood (American Society of Hematology) USA, Germany, 02 August 2012

Hematology

Key words: Leukocyte trafficking, ST3Gal subfamily, protein glycosylation

Organism: Mouse

Tissue: Lymphoid Tissue

1865
Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43

I-Fang Wang, Bo-Shen Guo, Yu-Chih Liu, Cheng-Chun Wu, Chun-Hung Yang, Kuen-Jer Che-Kun James Shen

PNAS (PNAS) USA, 02 August 2012

Neuroscience

Key words: Protein aggregation, neuronal apoptosis

1866
Chapter 9 - Correlated Light Microscopy and Electron Microscopy

Klaas A Sjollema, Ulrike Schnell, Jeroen Kuipers, Ruby Kalicharan, Ben NG Giepmans

Methods in Cell Biology (Elsevier) The Netherlands, 31 July 2012

Microscopy

Key words: Light microscopy, electron microscopy, correlated microscopy, orientation, probes, high resolution, drawing tube, mosaic microscopy

1867
Abstracts for the International Federation of Placenta Associations Meeting 2012

Placenta (Elsevier) , 25 July 2012

Reproductive Medicine

1868
Vasohibin-2 Expressed in Human Serous Ovarian Adenocarcinoma Accelerates Tumor Growth by Promoting Angiogenesis

Yoshifumi Takahashi, Takahiro Koyanagi, Yasuhiro Suzuki, Yasushi Saga, Naoki Kanomata, Takuya Moriya, Mitsuaki Suzuki, Yasufumi Sato

Molecular Cancer Research (AACR Publications) Japan, 23 July 2012

Oncology

Key words: Vasohibin-1, angiogenesis, ovarian cancer, Angiopoietins

Organism: Human

Tissue: Ovaries

Pathological State: Cancer

1869
The vitamin D receptor activator paricalcitol prevents fibrosis and diastolic dysfunction in a murine model of pressure overload

Laura MG Meems, Megan V Cannon, Hasan Mahmud, Adriaan A Voors, Wiek H van Gilst, Herman HW Silljé, Willem PT Ruifrok, Rudolf A de Boer

The Journal of Steroid Biochemistry and Molecular Biology (Elsevier) The Netherlands, 15 July 2012

Cardiology

Key words: Fibrosis, heart failure, paricalcitol, remodeling, vitamin D receptor, renin

Organism: Mouse

Tissue: Heart

Pathological State: Cardiac Fibrosis

1870
Tumour‐secreted miR‐9 promotes endothelial cell migration and angiogenesis by activating the JAK‐STAT pathway

Guanglei Zhuang, Xiumin Wu, Zhaoshi Jiang, Ian Kasman, Jenny Yao, Yinghui Guan, Jason Oeh, Zora Modrusan, Carlos Bais, Deepak Sampath, Napoleone Ferrara

EMBO Journal (EMBO press) USA, 06 July 2012

Oncology

Key words: Angiogenesis, Endothelium, JAK‐STAT, MicroRNA, Tumour

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

1871
1107 In Vitro Generated Human Dendritic Cells Exposed to a Potent Maturation Melanoma Cell Lines Lysate Show a Tolerogenic-like Phenotype and Functionality When Exposed to Dexamethasone Prior to the Maturation Stimuli

C Falcon-Beas, F Tempio, B Pesce, J Aguillon, C Pereda, C Saffie, F Salazar-Onfray, MN Lopez

European Journal of Cancer (Elsevier) , 06 July 2012

Oncology

1872
1110 Modulation of Genistein- and Resveratrol-induced Apoptosis and Cell Proliferation in Colon Cancer Cells

LI Brasoveanu, D Hotnog, C Hotnog, M Bostan, M Mihaila

European Journal of Cancer (Elsevier) , 06 July 2012

Oncology

1873
1109 Density and Organization of B Cells, Including the Activation-induced Cytidine Deaminase (AID)-positive Sub-population, Within Active Tumor Border of Human Colorectal Cancer Liver Metastases Shows a Positive Association With Survival Prognosis

A Meshcheryakova, M Svoboda, E Bajna, J Maresch, J Jensen-Jarolim, M Bergmann, D Tamandl, D Mechtcheriakova

European Journal of Cancer (Elsevier) , 06 July 2012

Oncology

1874
1108 Histidine-rich Glycoprotein Regulates Macrophage Differentiation

O Noguer, S Tugues, S Honjo, L Claesson-Welsh

European Journal of Cancer (Elsevier) , 06 July 2012

Oncology

1875
A Novel Nucleus-Based Classifier for Discrimination of Osteoclasts and Mesenchymal Precursor Cells in Mouse Bone Marrow Cultures

Andreas Heindl, Alexander K Seewald, Martin Schepelmann, Radu Rogojanu, Giovanna Bises, Theresia Thalhammer, and Isabella Ellinger

International Journal of Medical and Health Sciences (Open Science Index) Austria, 01 July 2012

Osteology

Key words: osteoclasts, machine learning, ellipse fitting.

1876
Pristane-induced lupus as a model of human lupus arthritis: evolvement of autoantibodies, internal organ and joint inflammation

H Leiss, B Niederreiter, T Bandur, B Schwarzecker, S Blüml, G Steiner, W Ulrich3, JS Smolen, GH Stummvoll

Lupus (SAGE Journals) Austria, 01 July 2012

Rheumatology

Key words: Lupus arthritis pristane-induced lupus (PIL), systemic lupus erythematosus (SLE)

Organism: Mouse

Tissue: Joint Tissue, Bone, Lung, Kidney

Pathological State: Arthritis, Lupus

1877
RasGRF1 regulates proliferation and metastatic behavior of human alveolar rhabdomyosarcomas

Maciej Tarnowski, Gabriela Schneider, Gabriele Amann, Geoffrey Clark, Peter Houghton, Frederic G Barr, Lukas Kenner, Mariusz Z Ratajczak, Magda Kucia

International Journal of Oncology (Spandidos Publications) USA, Austria, Poland, 28 June 2012

Oncology

Organism: Human

Tissue: Lung

Pathological State: Cancer

1878
Cisplatin and quantum dots encapsulated in liposomes as multifunctional nanocarriers for theranostic use in brain and skin

Li-Wen Zhang, Chih-Jen Wen, Saleh A Al-Suwayeh, Tzu-Chen Yen, Jia-You Fang

Journal of Nanoparticle Research (Springer) Taiwan, Saudi Arabia, 19 June 2012

Nanomedicine

Key words: Cdse zns qds, cdse zns nanocrystal, nude mouse skin, cdse zns quantum, cisplatin release, mouse skin section, blank liposome, cdse core, skin melanoma, vesicle size, quantum dot, entrapment efficiency, skin uptake, non-treatment group, cisplatin accumulation

Organism: Mouse

Tissue: Brain, Skin

1879
Monitoring neutrophils and platelets during casein-induced anaphylaxis in an experimental BALB/c mouse model

D Krishnamurti, P Starkl, K Szalai, F Roth-Walter, S C Diesner, M Mittlboeck, C Manhalter, E Untersmayr, E Jensen-Jarolim

Clinical and Experimental Allergy (Wiley) Austria, 15 June 2012

Allergy Research

Key words: Mast cells, basophils , alum-adsorbed casein, peripheral neutropenia

1880
Quantitative analysis of binding sites for 9-fluoropropyl-(+)-dihydrotetrabenazine ([18F]AV-133) in a MPTP-lesioned PD mouse model

Ko-Ting Chao, Hsin-Hsin Tsao, Yi-Hsin Weng, Ing-Tsung Hsiao, Chia-Ju Hsieh, Shiaw-Pyng Wey, Tzu-Chen Yen, Mei-Ping Kung,Kun-Ju Lin

Synapse (Wiley) Taiwan, 13 June 2012

Neuroscience

Key words: Positron emission tomography, quantitative autoradiography, immunohistochemistry, vesicular monoamine transporter 2, standardized uptake value

Organism: Mouse

Tissue: Brain

Pathological State: Parkinson's Disease

1881
Prognostic role of indoleamine 2,3-dioxygenase in endometrial carcinoma

Renske A de Jong, Ido P Kema, Annemarie Boerma, H Marike Boezen, Johannes JL van der Want, Marloes JM Gooden, Harry Hollema, Hans W Nijman

Gynecologic Oncology (Elsevier) The Netherlands, 02 June 2012

Oncology

Key words: Endometrial carcinoma, indoleamine 2, 3-dioxygenase, T-lymphocytes, prognosis

Organism: Human

Tissue: Endometrium

Pathological State: Cancer

1882
Evidence That Activated Hedgehog Signaling Predicts for Poor Clinical Outcome in Acute Myeloid Leukemia

Veronica Campbell, Eleni Tholouli, M Travis Quigley, John Keilty, Patrick Kelly, Karen McGovern, Margaret Read, Jeffery L Kutok, Richard Byers

Blood (American Society of Hematology) USA, UK, 01 June 2012

Oncology

Key words: Hedgehog (Hh), Acute Myeloid Leukemia (AML), Primary CD34+ myeloid blasts

Organism: Human

Tissue: Lymphoid Tissue

Pathological State: Cancer

1883
CD256 can be found in antibody-mediated renal allograft rejection tissues

Xu H, He X, Zhao W, Guo H, Shi Q, Zhu Y, Zhang X

Clinical Laboratory (NCBI) China, 01 June 2012

Transplantation Medicine

Key words: Tumor necrosis factor, Systemic lupus erythematosus, Rheumatoid arthritis, antibody-mediated rejection

1884
Type 2 diabetes mellitus is associated with an imbalance in circulating endothelial and smooth muscle progenitor cell numbers

J van Ark, J Moser, C P H Lexis, F Bekkema, I Pop, I C C van der Horst, C J Zeebregts, H van Goor, B H R Wolffenbuttel, J L Hillebrands

Diabetologia (Springer) The Netherlands, 01 June 2012

Endocrinology

Key words: smc marker gene, smc differentiation, epc count, mature smc, angiogenic cell, fibrous cap, cell subset, smc lineage, mature ecs, vascular repair, atherosclerotic plaque, real-time rt-pcr, repair capacity, endothelial differentiation, cell mobilisation

Organism: Human

Pathological State: Diabetes

Cell Line: PBMCs

1885
Clinical significance of the ratio between FOXP3 positive regulatory T cell and interleukin-17 secreting cell in renal allograft biopsies with acute T-cell-mediated rejection

Byung H Chung, Hye J Oh, Shang G Piao, Hyeon S Hwang, In O Sun, Sun R Choi, Hoon S Park, Bum S Choi, Yeong J Choi, Cheol W Park, Yong-SoKim, Mi-La Cho Chul W Yan

Immunology (Wiley) South Korea, 01 June 2012

Immunology

Key words: Acute T-cell-mediated rejection, FOXP3, interleukin-17, regulatory T cell, T helper type 17

Organism: Human

Tissue: Kidney

Pathological State: Organ Transplantation

1886
Point sur les avancées technologiques en hémocytométrie aux JIB 2011

F Berge , G Maggiore, A Frenkian

IRBM News (Elsevier) France, 01 June 2012

Cytometry

1887
Chemical shift MR imaging methods for the quantification of transcatheter lipiodol delivery to the liver: preclinical feasibility studies in a rodent model

Xiaoming Yin, Yang Guo, Weiguo Li, Eugene Huo, Zhuoli Zhang, Jodi Nicolai, Robert A Kleps, Diego Hernando, Aggelos K Katsaggelos, Reed A Omary, Andrew C Larson

Radiology (Radiological Society of North America) USA, 01 June 2012

Medical Image Analysis

Organism: Rat

Tissue: Liver

1888
96. Jahrestagung der Deutschen Gesellschaft für Pathologie e. V.

Der Pathologe (Springer) Germany, 27 May 2012

Pathology

1889
Neural precursors (NPCs) from adult L967Q mice display early commitment to “in vitro” neuronal differentiation and hyperexcitability

Francesca DiFebo, Daniela Curti, Francesca Botti, Gerardo Biella, Paolo Bigini, Tiziana Mennini, Mauro Toselli

Experimental Neurology (Elsevier) Italy, 22 May 2012

Neuroscience

Key words: Neural stem/progenitor cells (NPCs), motoneuron, neurodegeneration, amyotrophic lateral sclerosis, wobbler mouse, sodium channel, hyperexcitability, patch-clamp

Organism: Mouse

Tissue: Brain

1890
Snapshot spectral imaging using optimized diffractive optical elements

M De Biasio, T Arnold, A Tortschanoff, A Hermerschmidt, R Leitner

Next-Generation Spectroscopic Technologies (SPIE) Austria, Germany, 17 May 2012

Microscopy

Key words: snapshot, CTIS, DOE, optimization

1891
Selective CDK4/6 inhibition with tumor responses by PD0332991 in patients with mantle cell lymphoma

John P Leonard, Ann S LaCasce, Mitchell R Smith, Ariela Noy, Lucian R Chirieac, Scott J Rodig, Jian Q Yu, Shankar Vallabhajosula, Heiko Schoder, Patricia English, Donna S Neuberg, Peter Martin, Michael M Millenson, Scott A Ely, Rachel Courtney, Naveed Shaik, Keith D Wilner, Sophia Randolph, Annick D Van den Abbeele, Selina Y Chen-Kiang, Jeffrey T Yap, Geoffrey I Shapiro

Blood (American Society of Hematology) USA, 17 May 2012

Oncology

Key words: Mantle cell lymphoma, cyclin D1–dependent kinase activity, bortezomib, temsirolimus, lenalidomide

Organism: Human

Tissue: Lymphoid Tissue

Pathological State: Cancer

1892
RTEL1 contributes to DNA replication and repair and telomere maintenance

Evert-Jan Uringa, Kathleen Lisaingo, Hilda A Pickett, Julie Brind'Amour, Jan-Hendrik Rohde, Alex Zelensky, Jeroen Essers, Peter M Lansdorp

Molecular Biology of The Cell (American Society for Cell Biology) Canada, The Netherlands, Australia, 11 May 2012

Cell Biology

Key words: Telomere maintenance, DNA, mRtel1 , embryonic stem cells

Organism: Mouse

Cell Line: Embryonic stem cell

1893
Abating colon cancer polyposis by Lactobacillus acidophilus deficient in lipoteichoic acid

Khashayarsha Khazaie, Mojgan Zadeh, Mohammad W Khan, Praveen Bere, Fotini Gounari, Kirsten Dennis, Nichole R Blatner, Jennifer L Owen, Todd R Klaenhammerd, Mansour Mohamadzadeh

PNAS (PNAS) USA, 01 May 2012

Oncology

Key words: Dendritic cells regulatory, T cells anti-inflammatory

Organism: Mouse

Tissue: Colon

Pathological State: Cancer

1894
Magnesium sulfate and nimesulide have synergistic effects on rescuing brain damage after transient focal ischemia

LC Wang, CY Huang, HK Wang, MH Wu, KJ Tsai

Journal of Neurotrauma (Mary Ann Liebert Inc.) Taiwan, 25 April 2012

Neuroscience

Key words: in vivo studies, ischemia, middle cerebral artery occlusion, therapeutic approach, stroke

Organism: Rat

Tissue: Brain

Pathological State: Cerebral Ischemia

1895
Mice lacking epidermal PPARγ exhibit a marked augmentation in photocarcinogenesis associated with increased UVB-induced apoptosis, inflammation and barrier dysfunction

Ravi P Sahu, Sonia C DaSilva, Badri Rashid, Kellie Clay Martel, Danielle Jernigan, Shama R Mehta, Deena R Mohamed, Samin Rezania, Joshua R Bradish, Andrew B Armstrong, Simon Warren, Raymond L Konger

International Journal of Cancer (Wiley) USA, 18 April 2012

Oncology

Key words: Photocarcinogenesis, peroxisome proliferators activated receptor gamma, inflammation, apoptosis, differentiation, nonmelanoma skin cancer

Organism: Mouse

Tissue: Skin

Pathological State: Cancer

1896
Hedgehog pathway inhibitor saridegib (IPI-926) increases lifespan in a mouse medulloblastoma model

Michelle J Lee, Beryl A Hatton, Elisabeth H Villavicencio, Paritosh C Khanna, Seth D Friedman, Sally Ditzler, Barbara Pullar, Keith Robison, Kerry F White, Chris Tunkey, Michael LeBlanc, Julie Randolph-Habecker, Sue E Knoblaugh, Stacey Hansen, Andrew Richards, Brandon J Wainwright, Karen McGovern, James M Olson

PNAS (PNAS) USA, Australia, 04 April 2012

Oncology

Key words: Sonic Hedgehog (Shh) pathway, medulloblastomas, P-glycoprotein (Pgp)

1897
Injection of Amniotic Fluid Stem Cells Delays Progression of Renal Fibrosis

Sargis Sedrakyan, Stefano Da Sacco, Anna Milanesi, Liron Shiri, Astgik Petrosyan, Radka Varimezova, David Warburton, Kevin V Lemley, Roger E De Filippo, Laura Perin

Journal of The American Society of Nephrology (JASN) USA, 01 April 2012

Nephrology

Key words: Stem cells, renal fibrosis

Organism: Mouse

Tissue: Kidney

Pathological State: Renal Fibrosis

1898
Antagonistic effects of selenium and lipid peroxides on growth control in early hepatocellular carcinoma

Nataliya Rohr-Udilova, Wolfgang Sieghart, Robert Eferl, Dagmar Stoiber, Linda Björkhem-Bergman, Lennart C Eriksson, Klaus Stolze6 Hubert Hayden, Bernhard Keppler, Sandra Sagmeister, Bettina Grasl-Kraupp, Rolf Schulte-Hermann Markus Peck-Radosavljevic

Hepatology (Wiley) Austria, Sweden, 27 March 2012

Oncology

Key words: Vascular endothelial growth factor, hepatocellular carcinomas, antioxidative glutathione peroxidases

Organism: Human

Tissue: Liver

Pathological State: Cancer

1899
Requirement of Cellular Prion Protein for Intestinal Barrier Function and Mislocalization in Patients With Inflammatory Bowel Disease

Constance SV Peti, Frédérick Barreau, Laura Besnie, Pierre Gandill, Béatrice Rivea, Danielle Chatea, Maryline Ro, Dominique Berreb, Magali Svrce, Philippe Cardo, Monique Rousse, Caroline Clai, Sophie Thenet

Gastroenterology (Elsevier) France, 22 March 2012

Gastroenterology

Key words: Tight Junction, mouse model, cell–cell adhesion, inflammation

Organism: Human

Cell Line: Caco-2/TC7 enterocytes

1900
Biosafety of Non-Surface Modified Carbon Nanocapsules as a Potential Alternative to Carbon Nanotubes for Drug Delivery Purposes

Alan C L Tang, Gan-Lin Hwang, Shih-Jung Tsai, Min-Yao Chang, Zack C W Tang, Meng-Da Tsai, Chwan-Yao Luo, Allan S Hoffman, Patrick C H Hsieh

PLoS One (PLOS) Taiwan, USA, 22 March 2012

Nanomedicine

Key words: Carbon nanotubes, nanomaterials, drug delivery, toxicity, intravenous injections, cytokines, inflammation, alcohols

Organism: Mouse

1901
Induction of intestinal pro-inflammatory immune responses by lipoteichoic acid

Mojgan Zadeh, Mohammad W Khan, Yong Jun Goh, Kurt Selle, Jennifer L Owen, Todd Klaenhammer, Mansour Mohamadzadeh

Journal of Inflammation (Springer) USA, 16 March 2012

Immunology

Key words: Dendritic cell, dextran sulfate sodium, inflammatory bowel disease, lipoteichoic acid, toll-like receptor 2

Organism: Mouse

Tissue: Colon

Pathological State: Intestinal Inflammation

1902
Comparative oncology: ErbB-1 and ErbB-2 homologues in canine cancer are susceptible to cetuximab and trastuzumab targeting

Josef Singer, Marlene Weichselbaumera, Thomas Stockner, Diana Mechtcheriakova, Yury Sobanov, Erika Bajna, Friedrich Wrba, Reinhard Horvat, Johann G Thalhammer, Michael Willmann, Erika Jensen-Jarolim

Molecular Immunology (Elsevier) Austria, 16 March 2012

Oncology

Key words: Comparative oncology, ErbB-1, ErbB-2, Human, Canine, Breast cancer

Organism: Dog

Tissue: Breast

Pathological State: Cancer

1903
Involvement of the insular cortex in regulating glucocorticoid effects on memory consolidation of inhibitory avoidance training

R Fornari, R Wichmann, E Atucha, T Desprez, E Eggens-Meijer and B Roozendaal

Frontiers in behavioral neuroscience (Frontiers Media S.A.) The Netherlands, Brazil, 15 March 2012

Neuroscience

Organism: Rat

Tissue: Brain

1904
Preserved Function of Regulatory T Cells in Chronic HIV-1 Infection Despite Decreased Numbers in Blood and Tissue

Mathieu Angin, Douglas S Kwon, Hendrik Streeck, Fang Wen, Melanie King, Ashley Rezai, Kenneth Law, Tomoyuki C Hongo, Augustine Pyo, Alicja Piechocka-Trocha, Ildiko Toth, Florencia Pereyra, Musie Ghebremichael, Scott J Rodig, Danny A Milner Jr, James M Richter, Marcus Altfeld, Daniel E Kaufmann, Bruce D Walker, Marylyn M Addo

The Journal of Infectious Diseases (Oxford University Press) USA, 15 March 2012

Immunology, Virology

Key words: Regulatory T cells (Tregs), T lymphocytes, cytotoxic, lymphoid tissue (GALT)

Organism: Human

Tissue: Colon

Pathological State: HIV Infection

1905
Deficiency of the macrophage growth factor CSF-1 disrupts pancreatic neuroendocrine tumor development

SM Pyonteck, BB Gadea, HW Wang, V Gocheva, KE Hunter, LH Tang, JA Joyce

Oncogene (Nature) USA, 15 March 2012

Oncology

Organism: Human

Tissue: Pancreas

Pathological State: Cancer

1906
An Essential Role for Modulation of Hyperpolarization-Activated Current in the Development of Binaural Temporal Precision

Sukant Khurana, Zhiqiang Liu, Alan S Lewis, Kristen Rosa, Dane Chetkovich, Nace L Golding

Journal of Neuroscience (SFN) USA, 22 February 2012

Neuroscience

Key words: Medial superior olive , binaural neurons, hyperpolarization-activated current, cyclic nucleotide-gated (HCN) channels

Organism: Mongolian gerbil

Tissue: Brain

1907
Regulation of Axonal HCN1 Trafficking in Perforant Path Involves Expression of Specific TRIP8b Isoforms

Wiebke Wilkars , Zhiqiang Liu , Alan S Lewis, Travis R Stoub, Elena M Ramos, Nicola Brandt, Daniel A Nicholson, Dane M Chetkovich, Roland A Bender

PLoS One (PLOS) Germany, USA, 21 February 2012

Neuroscience

Key words: Neurons, neuronal dendrites, axons, neuronal differentiation, immunohistochemistry techniques, pyramidal cells, in situ hybridization, hippocampus

Organism: Mouse, Rat

Tissue: Brain

1908
Inhibition of CD26/DPP-IV enhances donor muscle cell engraftment and stimulates sustained donor cell proliferation

Maura H Parker, Carol Loretz, Ashlee E Tyler, Lauren Snider, Rainer Storb, Stephen J Tapscott

Skeletal Muscle (Springer) USA, 16 February 2012

Regenerative Medicine

Key words: Muscular dystrophy, cell transplantation, xenotransplant, canine, CXCR4, diprotin A

1909
Combined strategies of apomorphine diester prodrugs and nanostructured lipid carriers for efficient brain targeting

Kuo-Sheng Liu, Chih-Jen Wen, Tzu-Chen Yen, K C Sung, Ming-Chuan Ku, Jhi-Joung Wang, Jia-You Fang

Nanotechnology (IOP Science) Taiwan, Saudi Arabia, 10 February 2012

Nanomedicine

Key words: nanostructured lipid carriers, diacetyl apomorphine , diisobutyryl apomorphine, DAA, DIA

Organism: Mouse

Tissue: Brain

1910
Optimisation of the diffractive optical element for snapshot spectral imaging used in fluorescence microscopy

R Leitner, T Arnold, M De Biasio, G McGunnigle, R Rogojanu, G E Steiner, A Hermerschmidt

Computational Microscopy (SPIE) Austria, Germany, 09 February 2012

Microscopy

Key words: Luminescence, microscopy, optical components, maging spectroscopy, cameras, reconstruction algorithms, spectral resolution, spectrometers, imaging systems, computed tomography

1911
Polycaprolactone electrospun mesh conjugated with an MSC affinity peptide for MSC homing in vivo

Zhenxing Shao, Xin Zhang, Yanbin Pi, Xiaokun Wang, Zhuqing Jia, Jingxian Zhu, Linghui Dai, Wenqing Chen, Ling Yin, Haifeng Chen, Chunyan Zhou, Yingfang Ao

Biomaterials (Elsevier) China, 07 February 2012

Biological Materials

Key words: Phage display, tssue engineering (TE), MSC-homing, peptide-modified polycaprolactone electrospun mesh

Organism: Rat

1912
Soy Isoflavone Supplementation for Breast Cancer Risk Reduction: A Randomized Phase II Trial

Seema A Khan, Robert T Chatterton, Nancy Michel, Michelle Bryk, Oukseub Lee, David Ivancic, Richard Heinz, Carola M Zalles, Irene B Helenowski, Borko D Jovanovic, Adrian A Franke, Maarten C Bosland, Jun Wang, Nora M Hansen, Kevin P Bethke, Alexander Dew, Margerie Coomes, Raymond C Bergan

Cancer Prevention Research (AACR Publications) USA, 05 February 2012

Oncology

Key words: breast cancer, breast epithelial proliferation, random fine-needle aspiration

Organism: Human

Tissue: Breast

1913
Single-walled carbon nanotubes induce airway hyperreactivity and parenchymal injury in mice

WY Hsieh, CC Chou, CC Ho, SL Yu, HY Chen, HYE Chou, JJW Chen, HW Chen, PC Yang

American Journal of Respiratory Cell and Molecular Biology (ATS Journals) Taiwan, 01 February 2012

Nanomedicine

Key words: single-walled carbon nanotubes, toxicity, matrix metalloproteinase2, cathepsin K, NF-κB

Organism: Mouse

Tissue: Lung

1914
Swine Leukocyte Antigen-DQ Expression and Its Regulation by Interferon-Gamma at the Maternal-Fetal Interface in Pigs

Mingoo Kim, Heewon Seo, Yohan Choi, Jangsoo Shim, Fuller W Bazer, Hakhyun Ka

Biology of Reproduction (SSR) South Korea, 01 February 2012

Reproductive Medicine

Key words: Endometrium female reproductive tract pig pregnancy reproductive immunology SLA-DQ uterus

1915
Modulating intestinal immune responses by lipoteichoic acid-deficient Lactobacillus acidophilus

Mohammad W Khan, Mojgan Zadeh, Praveen Bere, Elias Gounaris, Jennifer Owen, Todd Klaenhammer, Mansour Mohamadzadeh

Immunotherapy (FSG) USA, 01 February 2012

Immunology

Key words: Microbe Lactobacillus acidophilus, lipoteichoic acid-deficient strain, dendritic cells and macrophages

Organism: Mouse

Tissue: Colon

Pathological State: Intestinal Inflammation

1916
Lamin A/C protein is overexpressed in tissue-invading prostate cancer and promotes prostate cancer cell growth, migration and invasion through the PI3K/AKT/PTEN pathway

Lu Kong, Georg Schäfer Huajie Bu, Yong Zhang, Yuxiang Zhang, Helmut Klocker

Carcinogenesis (Oxford University Press) Austria, China, 21 January 2012

Oncology

Key words: cell growth, 1-phosphatidylinositol 3-kinase , cell lines, neoplasms, prostate cancer, pten gene, protein overexpression, proto-oncogene proteins c-akt, phosphoinositide 3-kinase, lamin type a

Organism: Human

Cell Line: Human PC cell lines PC3 and DU145

1917
Intratumoral heterogeneity in anaplastic large cell lymphoma of non-common subtype

Dmitriy Abramov, Ilske Oschlies, Dmitriy Konovalov, Christine Damm-Welk, Wilhelm Wössmann, Wolfram Klapper

Journal of Hematopathology (Springer) Germany, Russia, 14 January 2012

Oncology

Key words: Anaplastic large cell lymphoma, ALK, Digital image analysis

Organism: Human

Tissue: Lymphoid Tissue

Pathological State: Cancer

1918
Tubular epithelial syndecan-1 maintains renal function in murine ischemia/reperfusion and human transplantation

Celie JW, Katta KK, Adepu S, Melenhorst WB, Reijmers RM, Slot EM, Beelen RH, Spaargaren M, Ploeg RJ, Navis G, van der Heide JJ, van Dijk MC, van Goor H, van den Born J

Kidney international (Elsevier) The Netherlands, 11 January 2012

Nephrology

Key words: kidney transplantation, proliferation, renal epithelial cell, renal ischemia-reperfusion, transplant outcomes

Organism: Mouse

Tissue: Kidney

Pathological State: Organ Transplantation

1919
A role for Epstein–Barr viral BALF1 in facilitating tumor formation and metastasis potential

Wen-Li Hsua, Pei-Jung Chungb, Ming-Hsien Tsaia, Cicero Lee-Tian Changc, Chih-Lung Liang

Virus research (Elsevier) Taiwan, 02 January 2012

Oncology, Virology

Key words: EBV, BALF1, Transformation, Tumor, Metastasis

Organism: Mouse

Pathological State: Epstein–Barr virus Infection, Cancer

1920
Robotic Microscopy and information technology to increase accuracy, sensitivity and availability of blood cell analyses

V Medovyi, A Pyatnitskiy

Current Microscopy Contributions to Advances in Science and Technology (FORMATEX) Russia, 01 January 2012

Microscopy

Key words: robotic microscopy, blood smear analysis, virtual slide, laboratory telemedicine, image cytometry, virtual microscopy, image analysis, pattern recognition, artificial intelligence

1921
Increased activation of the PI3K/AKT pathway compromises decidualization of stromal cells from endometriosis

X Yin, ME Pavone, Z Lu, JJ Wei, JJ Kim

Journal of Clinical Endocrinology and Metabolism (Oxford University Press) USA, 01 January 2012

Reproductive Medicine

Organism: Human

Tissue: Endometrium, Ovaries

Pathological State: Endometriosis

1922
Magnetization transfer MRI in pancreatic cancer xenograft models

Weiguo Li, Zhuoli Zhang, Jodi Nicolai, Guang-Yu Yang, Reed A Omary, Andrew C Larson

Magnetic Resonance in Medicine (Wiley) USA, 28 December 2011

Oncology

Key words: Magnetization transfer, fibrosis, pancreatic cancer, mouse xenograft model

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

1923
MicroRNA-1 and microRNA-206 improve differentiation potential of human satellite cells: a novel approach for tissue engineering of skeletal muscle

M Koning, PMN Werker, DWJ van der Schaft, RA Bank, MC Harmsen

Tissue Engineering Part A (Mary Ann Liebert Inc.) The Netherlands, 20 December 2011

Regenerative Medicine

Organism: Human

Tissue: Muscle

1924
Macrophages in human colorectal cancer are pro-inflammatory and prime T cells towards an anti-tumour type-1 inflammatory response

Siew-Min Ong, Yann-Chong Tan, Ottavio Beretta, Dongsheng Jiang, Wei-Hseun Yeap, June J Y Tai, Wing-Cheong Wong, Henry Yang, Herbert Schwarz, Kiat-Hon Lim, Poh-Koon Koh, Khoon-Lin Ling, Siew-Cheng Wong

European Journal of Immunology (Wiley) Singapore, 12 December 2011

Immunology

Key words: Chemokines, cytokines, spheroid model, T-cell co-stimulation, tumour-associated macrophages (TAMs)

Organism: Human

Tissue: Colon

Pathological State: Cancer

1925
Sensorimotor assessment of the unilateral 6-hydroxydopamine mouse model of Parkinson's disease

KE Glajch, SM Fleming, DJ Surmeier, P Osten

Behavioural Brain Research (Elsevier) USA, 09 December 2011

Neuroscience

Key words: Parkinson's disease, 6-OHDA, Mouse, Behavioral test, Sensorimotor impairment, Medial forebrain bundle

Organism: Mouse

Tissue: Brain

Pathological State: Parkinson's disease

1926
Digital Transplantation Pathology: Combining Whole Slide Imaging, Multiplex Staining and Automated Image Analysis

K Isse, A Lesniak, K Grama, B Roysam, M I Minervini A J Demetris

American Journal of Transplantation (Wiley) USA, 04 November 2011

Transplantation Medicine

Key words: Allograft pathology, C4d, digital image, fibrosis, quantitative analysis, quantum dots, three-dimensional imaging

1927
Gas challenge–blood oxygen level-dependent (GC-BOLD) MRI in the rat Novikoff hepatoma model

Yang Guo, Ning Jin, Rachel Klein, Jodi Nicolai, Guang-Yu Yang, Reed A Omary, Andrew C Larson

Magnetic Resonance Imaging (Elsevier) USA, 04 November 2011

Oncology

Key words: Gas challenge–blood oxygen level dependent (GC-BOLD), MRI, Rat Novikoff hepatoma, Tumor angiogenesis, Tumor microvessel density

Organism: Rat

Tissue: Liver

Pathological State: Cancer

1928
Epithelial Area Detection in Cytokeratin Microscopic Images Using MSER Segmentation in an Anisotropic Pyramid

Cristian Smochina, Radu Rogojanu, Vasile Manta, Walter Kropatsch

Pattern Recognition in Bioinformatics (Springer) Romania, Austria, 01 November 2011

Medical Image Analysis

Key words: Crypt segmentation, Anisotropic diffusion pyramid, MSER, Biomedical imaging, Pathology, Microscopy, Fluorescence microscopy, Image analysis

Organism: Human

Tissue: Colon

Pathological State: Cancer

1929
Evaluation of Functional and Structural Alterations in Muscle Tissue after Short-Term Cold Storage in a New Tissue Preservation Solution

Wille T, Gonder S, Thiermann H,Seeger T,Rauen U, Worek F

Cells Tissues Organs (Karger) Germany, 01 November 2011

Regenerative Medicine

Key words: Muscle tissue, preservation solution

Organism: Mouse

Tissue: Muscle

1930
Impact of interleukin-21 in the pathogenesis of primary Sjogren's syndrome: increased serum levels of interleukin-21 and its expression in the labial salivary glands

Kwi Young Kang, Hyun-Ok Kim, Seung-Ki Kwok, Ji Hyeon Ju, Kyung-Su Park, Dong-Il Sun, Joo Yeon Jhun, Hye Jwa Oh, Sung-Hwan Park, Ho-Youn Kim

Arthritis Research and Therapy (Springer) South Korea, 26 October 2011

Rheumatology

Key words: Serum il-21, anti-ro ssa antibody, synovial membrane cell, labial salivary gland, il-21r expression, il-21 gene, anti-ro la antibody, salivary gland biopsy, tfh cell, ectopic germinal center, encephalitis, th17 cell, nkt cell, il-21 concentration, ductal cell

Organism: Human

Tissue: Salivary Gland

Pathological State: Sjögren's syndrome

1931
Regulation of Oocyte and Cumulus Cell Interactions by Intermedin/Adrenomedullin 2

Chia Lin Chang, Hsin-Shih Wang, Yung-Kuei Soong, Shang Yu Huang, Shun Yuan Pa, Sheau Yu Teddy Hsu

Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) Taiwan, USA, 18 October 2011

Reproductive Medicine

Key words: Apoptosis, Bioinformatics, Cell Compartmentation, Cyclic AMP (cAMP), G Protein-coupled Receptors (GPCR), Ovary Peptide Hormones Adrenomedullin CGRP

Organism: Mouse

Tissue: Ovaries

1932
Sampling step importance in hierarchical semantic segmentation of microscopic images

Smochina C, Manta V, Kropatsch W

System Theory, Control, and Computing (IEEEXplore) Romania, Austria, 16 October 2011

Microscopy

Key words: Semantic segmentation of microscopic images

1933
Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer

Tanaya Shree, Oakley C Olson, Benelita T Elie, Jemila C Kester, Alfred L Garfall, Kenishana Simpson, Katherine M Bell-McGuinn, Emily C Zabor, Edi Brogi, Johanna A Joyce

Genes and Development (CSH Press) USA, 12 October 2011

Oncology

Key words: Cancer metastasis, chemotherapy, tumor microenvironment, proteolysis paclitaxel

Organism: Mouse

Tissue: Lung

Pathological State: Cancer

1934
Activation-Induced Cytidine Deaminase (AID)-Associated Multigene Signature to Assess Impact of AID in Etiology of Diseases with Inflammatory Component

Diana Mechtcheriakova, Yury Sobanov, Gabriele Holtappels, Erika Bajna, Martin Svoboda, Markus Jaritz, Claus Bachert, Erika Jensen-Jarolim

PLoS One (PLOS) Austria, Belgium, 03 October 2011

Immunology

Key words: Immunity, inflamation

Organism: Human

Tissue: Mucosa

Pathological State: Rhinosinusitis, Nasal polyps

1935
Evaluating the role of connexin43 in congenital heart disease: Screening for mutations in patients with outflow tract anomalies and the analysis of knock-in mouse …

GY Huang, LJ Xie, KL Linask, C Zhang, XQ Zhao, YI Yang, GM Zhou, YJ Wu, L Marquez-Rosado, DB McElhinney, E Goldmuntz, C Liu, PD Lampe, B Chatterjee, CW Lo

Journal of Cardiovascular Disease Research (Elsevier) USA, China, 01 October 2011

Cardiology

Key words: Connexin43, congenital heart disease, gap junction, knock-in mouse model, outflow tract, phosphorylations

Organism: Mouse

Tissue: Heart

Pathological State: Heart disease

1936
Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice

Kristina M Mueller, Jan-Wilhelm Kornfeld, Katrin Friedbichler, Leander Blaas, Gerda Egger, Harald Esterbauer, Peter Hasselblatt, Michaela Schlederer, Susanne Haindl, Kay-Uwe Wagner, David Engblom, Guenter Haemmerle, Dagmar Kratky, Veronika Sexl, Lukas Kenner, Andrey V Kozlov, Luigi Terracciano, Rudolf Zechner, Guenther Schuetz, Emilio Casanova, J Andrew Pospisilik, Markus H Heim, Richard Moriggl

Hepatology (Wiley) Austria, Germany, USA, Sweden, Switzerland, 27 September 2011

Oncology

Key words: Growth hormone (GH), peroxisome proliferator, systemic lipid homeostasis

Organism: Mouse

Tissue: Liver

Pathological State: Steatosis, Cancer

1937
Soluble gp130 Regulates Prostate Cancer Invasion and Progression in an Interleukin-6 Dependent and Independent Manner

Shahrokh F Shariat, Thomas F Chromecki, Julia Hoefer, Christopher E Barbieri, Douglas S Scherr, Pierre I Karakiewicz, Claus G Roehrborn, Francesco Montoris, Zoran Culigd, Ilaria T Cavarretta

Journal of Urology (Elsevier) USA, Austria, Italy, Canada, 23 September 2011

Oncology

Key words: Prostate, prostatic neoplasms, neoplasm invasiveness, cytokine receptor gp130, biological markers

Organism: Human

Pathological State: Cancer

Cell Line: Prostate stromal cells

1938
Angiopoietin-Like 4 Regulates Epidermal Differentiation

Mintu Pal, Ming Jie Tan, Royston-Luke Huang, Yan Yih Goh, Xiao Ling Wang, Mark Boon Yang Tang, Nguan Soon Tan

PLoS One (PLOS) Singapore, 22 September 2011

Dermatology

Key words: Keratinocytes, cell differentiation, epidermis, immunoblotting, biopsy, DNA transcription, messenger RNA, wound healing

Organism: Mouse

Tissue: Skin

1939
Semantic Segmentation of Microscopic Images Using a Morphological Hierarchy

Cristian Smochina, Vasile Manta, Walter Kropatsch

Computer Analysis of Images and Patterns (Springer) Romania, Austria, 31 August 2011

Medical Image Analysis

Key words: Crypt segmentation, Morphological hierarchy, Biomedical imaging, Pathology, Microscopy

Organism: Human

Tissue: Small Intestine, Colon

1940
Abstracts for the IFPA Meeting 2011

Placenta (Elsevier) Austria, 27 August 2011

1941
Expression of the IGF Axis Is Decreased in Local Prostate Cancer but Enhanced after Benign Prostate Epithelial Differentiation and TGF-β Treatment

Petra Massoner, Michael Ladurner Rennau, Isabel Heidegger, Anita Kloss-Brandstätter, Monika Summerer, Eva Reichhart, Georg Schäfer, Helmut Klocker

The American Journal of Pathology (Elsevier) Austria, 26 August 2011

Oncology

Key words: Insulin-like growth factor (IGF),

Organism: Human

Tissue: Prostate

Pathological State: Cancer

1942
Higher infiltration by Th17 cells compared with regulatory T cells is associated with severe acute T-cell-mediated graft rejection

Byung Ha Chung, Hye Jwa Oh, Shang Guo Piao, In O Sun, Seok Hui Kang, Sun Ryoung Choi, Hoon Suk Park, Bum Soon Choi, Yeong Jin Choi, Cheol Whee Park, Yong-Soo Kim, Mi-La Cho and Chul Woo Yang

Experimental and Molecular Medicine (Nature) South Korea, 24 August 2011

Immunology

Organism: Human

Tissue: Kidney

Pathological State: Organ Transplantation

1943
Modifiers of mutant huntingtin aggregation: functional conservation of C. elegans-modifiers of polyglutamine aggregation

Eva Teuling, Annika Bourgonje, Sven Veenje, Karen Thijssen, Jelle de Boer, Joeri van der Velde, Morris Swertz, Ellen Nollen

Plos Currents (PLOS) The Netherlands, 12 August 2011

Physiology

Organism: Human

Cell Line: HEK293-cells

1944
Spatiotemporal expression of SERPINE2 in the human placenta and its role in extravillous trophoblast migration and invasion

Schu-Rern Chern, Sheng-Hsiang Li, Chien-Ling Chiu, Hsiao-Ho Chang, Chih-Ping Chen, Edmund I Tsuen Chen

Reproductive Biology and Endocrinology (Springer) Taiwan, 02 August 2011

Reproductive Medicine

Key words: SERPINE2, plasminogen activator (PA) system, tissue remodeling, pregnancy, trophoblasts

Organism: Human

Tissue: Placenta

1945
Herpesvirus Entry Mediator and Nectin-1 Mediate Herpes Simplex Virus 1 Infection of the Murine Cornea

Andrew H Karaba, Sarah J Kopp and Richard Longnecker

Journal of Virology (American Society for Microbiology) USA, 27 July 2011

Virology

Key words: Herpes, infection

Organism: Mouse

Tissue: Eye

Pathological State: Herpes simplex Infection

1946
Expression of a functional VEGFR-1 in tumor cells is a major determinant of anti-PlGF antibodies efficacy

Jenny Yao, Xiumin Wu, Guanglei Zhuang, Ian M Kasman, Tobias Vogt, Vernon Phan, Masabumi Shibuya, Napoleone Ferrara, Carlos Bais

PNAS (PNAS) Japan, Italy, 12 July 2011

Oncology

Key words: Stroma tyrosine, kinase placental growth, factor vascular, endothelial growth, factor angiogenesis

1947
Kupffer cells support extramedullary erythropoiesis induced by nitrogen-containing bisphosphonate in splenectomized mice

Hirotada Otsuka, Hideki Yagi, Yasuo Endo, Naoko Nonaka, Masanori Nakamura

Cellular Immunology (Elsevier) Japan, 05 July 2011

Immunology

Key words: Nitrogen-containing bisphosphonate (NBP), Kupffer cell, Extramedullary erythropoiesis

Organism: Mouse

Tissue: Liver, Bone

1948
Modeling Colon Adenocarcinomas in Vitro: A 3D Co-Culture System Induces Cancer-Relevant Pathways upon Tumor Cell and Stromal Fibroblast Interaction

Helmut Dolznig, Christian Rupp, Christina Puri, Christian Haslinger, Norbert Schweifer, Elisabeth Wieser, Dontscho Kerjaschki, Pilar Garin-Chesa

The American Journal of Pathology (Elsevier) Austria, 01 July 2011

Oncology

Key words: Colon adenocarcinoma, in vitro

Organism: Human

Pathological State: Cancer

Cell Line: Cancer-associated fibroblasts

1949
The Presence and Localization of Melatonin Receptors in the Rat Aorta

Martin Schepelmann, Lubos Molcan, Hana Uhrova, Michal Zeman, Isabella Ellinger

Cellular and Molecular Neurobiology (Springer) Austria, Slovakia, 22 June 2011

Neuroscience

Key words: Mt1 receptor, saponin, arterial stiffness, melatonin concentration, rhythmic gene expression, rat eyerenal artery, clock gene bmal1, nadph oxidase, pineal gland , nocturnal hypertension

Organism: Rat

Tissue: Blood Vessels

1950
FTY720 Reduces Post-Ischemic Brain Lymphocyte Influx but Does Not Improve Outcome in Permanent Murine Cerebral Ischemia

Arthur Lie, Li Sun, Wei Zhou, Sönke Schwarting, Eva Mracsko, Markus Zorn, Henrike Bauer, Clemens Sommer, Roland Veltkamp

PLoS One (PLOS) Germany, 20 June 2011

Neuroscience

Key words: Ischemic strok e, Cerebral ischemia, Lymphocytes, Cytokines, T cells, Granulocytes, White blood cells, Monocytes

1951
An rhs gene of Pseudomonas aeruginosa encodes a virulence protein that activates the inflammasome

Vanderlene L Kung, Sonal Khare, Christian Stehlik, Elizabeth M Bacon, Ami J Hughes, Alan R Hauser

PNAS (PNAS) USA, 09 June 2011

Pathology

Key words: Rhs element, YD repeat, pathogenesis

1952
Spontaneous and aging-dependent development of arthritis in NADPH oxidase 2 deficiency through altered differentiation of CD11b+ and Th/Treg cells

Kihyun Lee, Hee Yeon Won, Myung Ae Bae, Jeong-Ho Hong, Eun Sook Hwang

PNAS (PNAS) South Korea, 07 June 2011

Rheumatology

Key words: Rheumatoid arthritis myeloid-derived suppressor cell

1953
Vasculatures in Tumors Growing From Preirradiated Tissues: Formed by Vasculogenesis and Resistant to Radiation and Antiangiogenic Therapy

Fang-Hsin Chen, Chi-Shiun Chiang, Chun-Chieh Wang, Sheng-Yung Fu, Chien-Sheng Tsai, Shih-Ming Jung, Chih-Jen Wen, Chung-Chi Lee, Ji-Hong Hong

International Journal of Radiation Oncology*Biology*Physics (Elsevier) Taiwan, 27 May 2011

Oncology

Key words: Radiation, Tumor bed effects, Microvascular density, Green fluorescent protein–tagged bone marrow, Antiangiogenic therapy

1954
Cytosolic DNA Triggers Inflammasome Activation in Keratinocytes in Psoriatic Lesions

Yvonne Dombrowski, Mark Peric, Sarah Koglin, Claudia Kammerbauer, Christine Göß, David Anz, Maren Simanski, Regine Gläser, Jürgen Harder, Veit Hornung, Richard L Gallo, Thomas Ruzicka, Robert Beschand, Jürgen Schauber

Science Translational Medicine (American Association for the Advancement of Science) Germany, USA, 11 May 2011

Dermatology

Key words: Psoriasis, keratinocytes, antimicrobial cathelicidin peptide LL-37,

1955
Influence of melatonin on murine osteoclast formation in culture — Automated detection and quantification by a novel image analysis system

M Schepelmann, A Heindl, A Seewald, A Nussbaumer, G Bises, R Rogojanu, P Pietschmann, I Ellinger, T Thalhammer

Bone (Elsevier) Austria, 07 May 2011

Medical Image Analysis

1956
Automated detection, quantification and characterization of osteoclasts in cultures using a combined image-processing and machine-learning strategy

A Heindl, M Schepelmann, R Stumberger, A Nussbaumer, c, P Pietschmann, G Bisesa, R Rogojanu, d, T Thalhammer, A Seewald, I Ellinger

Bone (Elsevier) Austria, 07 May 2011

Medical Image Analysis

Key words: Osteoclasts

1957
The analysis of organic anion transporting polypeptide (OATP) mRNA and protein patterns in primary and metastatic liver cancer

Katrin Wlcek, Martin Svoboda, Juliane Riha, Susanna Zakaria, Ulrike Olszewski, Zdenek Dvorak, Franz Sellner, Isabella Ellinger, Walter Jäger, Theresia Thalhammer

Cancer Biology and Therapy (Taylor and Francis) Austria, 01 May 2011

Oncology

Key words: Polypeptides, cholangiocellular carcinoma, hepatocellular carcinoma

1958
Segmentation of cell nuclei within chained structures in microscopic images of colon sections

C Smochina, A Serban, V Manta

Proceedings of the 27th Spring Conference on Computer Graphics (Association for Computing Machinery) Romania, 30 April 2011

Medical Image Analysis

Key words: Image segmentation, biomedical imaging, nucleus segmentation.

1959
Aberrant expression of CD30 in neoplastic mast cells in high-grade mastocytosis

Sotlar K, Cerny-Reiterer S, Petat-Dutter K, Hessel H, Berezowska S, Müllauer L, Valent P, Horny HP

Modern Pathology (NCBI) Germany, 24 April 2011

Pathology

Key words: Neoplastic mast cells, mastocytosis, reactive mast cell hyperplasia

1960
248 ANALYSIS AND CHARACTERIZATION OF HBVDNA INTEGRATION IN PATIENTS WITH OCCULT HBV INFECTION AND HEPATOCELLULAR CARCINOMA

C Saitta, T Pollicino, G Raffa, A Bertuccio, A Barbera, A Ciancio, A Smedile, G Navarra, G Raimondo

Journal of Hepatology (Elsevier) Italy, 18 April 2011

Oncology

Pathological State: Cancer

1961
247 MCL-1 IS A NEW P53 FAMILY TARGET GENE IN HEPATOCELLULAR CARCINOMA

A Pelc, K Roos, M Meinhard, H Mundt, B Besenbeck, H Schulze-Bergkamen, W Stremmel, M Müller

Journal of Hepatology (Elsevier) Germany, 18 April 2011

Oncology

1962
246 NUCLEAR TRANSLOCATION OF C-JUN AND MALIGNANT POTENTIAL IN HEPATOCELLULAR CARCINOMA PATIENTS UNDERGOING ORTHOTOPIC LIVER TRANSPLANTATION

N Rohr-Udilova, W Sieghart, R Eferl, M Peck-Radosavljevic

Journal of Hepatology (Elsevier) , 18 April 2011

Transplantation Medicine

1963
249 CHANGES IN TUMOR STIFFNESS FOR EARLY PREDICTION OF TUMOR RESPONSE TO SORAFENIB: A PROOF-OF-CONCEPT STUDY WITH ELASTOSONOGRAPHY IN AN ANIMAL MODEL OF HEPATOCELLULAR CARCINOMA (HCC)

V Salvatore, M Baron Toaldo, S Marinelli, C Palamà, L Gramantieri, M Cipone, L Bolondi, F Piscaglia

Journal of Hepatology (Elsevier) Italy, 18 April 2011

Oncology

1964
Effector T-Cell Infiltration Positively Impacts Survival of Glioblastoma Patients and Is Impaired by Tumor-Derived TGF-β

Jennifer Lohr, Thomas Ratliff, Andrea Huppertz, Yingzi Ge, Christine Dictus, Rezvan Ahmadi, Stefan Grau, Nobuyoshi Hiraoka, Volker Eckstein, Rupert C Ecker, Thomas Korff, Andreas von Deimling, Andreas Unterberg, Philipp Beckhove, Christel Herold-Mende

Clinical Cancer Research (AACR Publications) Germany, 08 April 2011

Oncology

Key words: Tumor, flow citometry

1965
Expression of organic anion-transporting polypeptides 1B3, 1B1, and 1A2 in human pancreatic cancer reveals a new class of potential therapeutic targets

Kounnis V, Ioachim E, Svoboda M, Tzakos A, Sainis I, Thalhammer T, Steiner G, Briasoulis E

OncoTargets and Therapy (Dove Press) Greece, Austria, 08 April 2011

Oncology

Key words: organic anion-transporting polypeptides, targeted therapy, transporter

1966
Effect of Additional Boron on Tibias of African Ostrich Chicks

Jiayue Cheng, Kemei Peng, Erhui Jin, Yong Zhang, Yan Liu, Ningbo Zhang, Hui Song, Huazhen Liu, Zhonglin Tang

Biological Trace Element Research (Springer) China, 02 April 2011

Biological Materials

Key words: Ostrich chick, cortical bone thickness, bone volume fraction, boron intake, trabecular bone microarchitecture, boron addition, ovx rat, boron content, dietary boron bone strength, calcium phosphate, bone turnover, drinking water, bone mass

1967
SERPINE2, an inhibitor of plasminogen activators, is highly expressed in the human endometrium during the secretory phase

Robert Kuo-Kuang Lee, Chi-Chen Fan, Yuh-Ming Hwu, Chung-Hao Lu, Ming-Huei Lin, Ying-Jie Chen, Sheng-Hsiang Li

Reproductive Biology and Endocrinology (Springer) Taiwan, 23 March 2011

Reproductive Medicine

Key words: protease nexin-1, plasminogen activators (PAs), SERPIN inhibitors, menstrual cycle

1968
Hypoxia promotes proliferation of human myogenic satellite cells: a potential benefactor in tissue engineering of skeletal muscle

Merel Koning, Paul MN Werker, Marja JA van Luyn, and Martin C Harmsen

Tissue Engineering Part A (Mary Ann Liebert Inc.) The Netherlands, 23 March 2011

Regenerative Medicine

1969
Phylogenetic discordance of human and canine carcinoembryonic antigen (CEA, CEACAM) families, but striking identity of the CEA receptors will impact …

Marlene Weichselbaumer, Michael Willmann, Martin Reifinger, Josef Singer, Erika Bajna, Yuriy Sobanov, Diana Mechtcherikova, Edgar Selzer, Johann G Thalhammer, Robert Kammerer, Erika Jensen-Jarolim

Plos Currents (PLOS) Austria, Germany, 16 March 2011

Oncology

1970
Angiopoietin-like 4 Protein Elevates the Prosurvival Intracellular O2-: H2O2 Ratio and Confers Anoikis Resistance to Tumors

Pengcheng Zhu, Ming Jie Tan, Royston-Luke Huang, Chek Kun Tan, Han Chung Chong, Mintu Pal, Chee Ren Ivan Lam, Petra Boukamp, Jiun Yit Pan, Suat Hoon Tan, Sander Kersten, Hoi Yeung Li, Jeak Ling Ding, and Nguan Soon Tan

Cancer Cell (Cell Press) Singapore, 14 March 2011

Oncology

1971
Antioxidant signaling via Nrf2 counteracts lipopolysaccharide-mediated inflammatory responses in foam cell macrophages

Anne-Marie Kuhn, Nico Tzieply, Martina Victoria Schmidt, Andreas von Knethen, Dmitry Namgaladze, Masayuki Yamamoto, Bernhard Brüne

Free Radical Biology and Medicine (Elsevier) Germany, Japan, 05 March 2011

Immunology

Key words: Foam cell, OxLDL, Nrf2, C/EBP, Desensitized phagocytes, Free radicals

1972
Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells

Shilpee Dutt, Anupama Narla, Katherine Lin, Ann Mullally, Nirmalee Abayasekara, Christine Megerdichian, Frederick H Wilson, Treeve Currie, Arati Khanna-Gupta, Nancy Berliner, Jeffery L Kutok, Benjamin L Ebert

Blood (American Society of Hematology) USA, 03 March 2011

Physiology

Key words: Flow citometry, cell cycle analysis

1973
Mast Cell 5-Lipoxygenase Activity Promotes Intestinal Polyposis in APCΔ468 Mice

Eric C Cheon, Khashayarsha Khazaie, Mohammad W Khan, Matthew J Strouch, Seth B Krantz, Joseph Phillips, Nichole R Blatner, Laura M Hix, Ming Zhang, Kristen L Dennis, Mohammed R Salabat, Michael Heiferman, Paul J Grippo, Hidayatullah G Munshi, Elias Gounaris, David J Bentrem

Cancer Research (AACR Publications) USA, 01 March 2011

Oncology

Key words: Arachidonic acid metabolism, colon carcinogenesis, hematopoietic 5-lipoxygenase (5LO), myeloid-derived suppressor cells (MDSCs)

1974
Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke

Arthur Liesz, Wei Zhou, Éva Mracskó, Simone Karcher, Henrike Bauer, Sönke Schwarting, Li Sun, Dunja Bruder, Sabine Stegemann, Adelheid Cerwenka, Clemens Sommer, Alexander H Dalpke, Roland Veltkamp

Brain (Oxford University Press) Germany, 25 February 2011

Neuroscience

Key words: Brain ischaemia, T cellVLA-4VCAM-1, inflammation

1975
In Vitro Dedifferentiation of Melanocytes from Adult Epidermis

Bernadett Kormos , Nóra Bels, Attila Bebes, Gábor Szabad, Sarolta Bacsa, Márta Széll, Lajos Kemény, Zsuzsanna Bata-Csörg

PLoS One (PLOS) Hungary, 23 February 2011

Dermatology

Key words: Melanocyts, Ultraviolet , Keratinocytes, Nestin, Cell differentiation, Protein expression, Adults, Epidermis

1976
Single chain anti-c-Met antibody conjugated nanoparticles for in vivo tumor-targeted imaging and drug delivery

Ruei-Min Lu, Yu-Ling Chang, Min-Shan Chen, Han-Chung Wu

Biomaterials (Elsevier) Taiwan, 08 February 2011

Medical Imaging

Key words: c-Met, Phage display, scFv, Drug delivery system, Immunoliposome

Pathological State: Cancer

1977
Adeno-associated virus-mediated anti-DR5 chimeric antibody expression suppresses human tumor growth in nude mice

Fujia Lv, Yuhe Qiu, Yaxi Zhang, Shilian Liu, Juan Shi, Yanxin Liu, Dexian Zheng

Cancer Letters (Elsevier) China, 08 February 2011

Oncology

Key words: Chimeric antibody, Death receptor 5, Gene transfer, Cancer therapy

1978
Clinical and Cytological Effects of Pimecrolimus Cream 1% after Resolution of Active Atopic Dermatitis Lesions by Topical Corticosteroids: A Randomized Controlled Trial

Bangert C, Strober BE, Cork M, Ortonne J-P, Luger T, Bieber T, Ferguson A, Ecker RC, Kopp T, Weise-Riccardi S, Guettner A, Stingl G

Dermatology (Karger) Austria, USA, UK, France, Germany, 01 February 2011

Dermatology

Key words: Skin biopsies, dendritic cells, Langerhans cells, T cells, betamethasone-17α-valerate-induced AD

1979
Irreversible electroporation in the liver: contrast-enhanced inversion-recovery MR imaging approaches to differentiate reversibly electroporated penumbra from Irreversibly Electroporated Ablation Zones

Yang Guo, Yue Zhang, Grace M Nijm, Alan V Sahakian, Guang-Yu Yang, Reed A Omary, Andrew C Larson

Radiology (Radiological Society of North America) USA, 01 February 2011

Hepathology

1980
α-Catulin knockdown induces senescence in cancer cells

LC Fan, WF Chiang, CH Liang, YT Tsai, TY Wong, KC Chen, TM Hong, YL Chen

Oncogene (Nature) Taiwan, 31 January 2011

Oncology

Key words: Cancer, Gene regulation, Oncogenesis, Senescence

1981
Entry of a heparan sulphate-binding HRV8 variant strictly depends on dynamin but not on clathrin, caveolin, and flotillin

Abdul Ghafoor Khan, Angela Pickl-Herk, Leszek Gajdzik, Thomas C Marlovits, Renate Fuchs, Dieter Blaas

Virology (Elsevier) Austria, 22 January 2011

Virology

Key words: Rhinovirus, Endocytosis, Dynamin, Macropinocytosis, Entry inhibitors, Endocytic pathway, Heparan sulphate, ICAM-1, Clathrin

1982
Perifosine and CCI 779 Co-Operate to Induce Cell Death and Decrease Proliferation in PTEN-Intact and PTEN-Deficient PDGF-Driven Murine Glioblastoma

Kenneth L Pitter, Craig J Galbán, Stefanie Galbán, Omid Saeed-Tehrani, Fei Li, Nikki Charles, Michelle S Bradbury, Oren J Becher, Thomas L Chenevert, Alnawaz Rehemtulla, Brian D Ross , Eric C Holland , Dolores Hambardzumyan

PLoS One (PLOS) USA, 18 January 2011

Oncology

Key words: Glioma, Magnetic resonance imaging, Glioma cells, Adenocarcinomas, Cell death, In vivo imaging, Apoptosis

1983
Detection of Nucleated Red Blood Cells in Maternal Circulation by Magnetic Sorting and in situ Hybridization

D Nemescu, D Constantinescu, V Martiniuc…

Gineco+ro () Romania, 01 January 2011

Reproductive Medicine

Key words: prenatal diagnosis, erythroblast, CD71, magnetic-activated cell sorting (MACS), flu o res cent in situ hybridization (FISH)

1984
Novel Molecular Strategy Tests, Issued by Laparoscopy, That Can Predict the Progression and Severity of Endometriotic Disease

JB de la Joliniere, G Lesec, C Real, JM Ayoubi

Journal of Minimally Invasive Gynecology (AAGL) France, 01 January 2011

Reproductive Medicine

1985
CORRELATIONS RELATED MORPHOFUNTIONAL ORGANIZATION OF ESOPHAGUS AND ITS TRANSPORT FUNCTION.

Goian, L, Veliceasa, B, Tărniceriu, Cristina Claudia, Frâncu, L L

Romanian Journal of Functional and Clinical, Macro- and Microscopical Anatomy and of Anthropology () Romania, 01 January 2011

Gastroenterology

1986
THE QUALITATIVE MICROANATOMICAL ANALYSIS OF THE DISTRIBUTION OF THE INTRAMURAL BLOOD VESSELS IN THE ESOPHAGUS.

L Goian, CC Tărniceriu, LL Francu

Romanian Journal of Functional and Clinical, Macro- and Microscopical Anatomy and of Anthropology () Romania, 01 January 2011

Cardiology

1987
Enhanced sensitivity to Botulinum type A neurotoxin of human neuroblastoma SH-SY5Y cells after differentiation into mature neuronal cells

C Rasetti-Escargueil, CB Machado, R Preneta-Blanc

The Botulinum Journal (InderScience Publishers) UK, 01 January 2011

Toxicology

Key words: BoNT, Botulinum neurotoxin, neurotransmitter release, SH-SY5Y cell line, human neuroblastoma cells, differentiation, cell based assay, synaptic vesicles recycling.

1988
Principles of Osteoimmunology

P Pietschmann

(Springer) Austria, 01 January 2011

Immunology

1989
Multifunctional hollow nanoparticles based on graft-diblock copolymers for doxorubicin delivery

Pei-Lin Lu, Yi-Chun Chen,Ta-Wei Ou, Hung-Hao Chen, Hsieh-Chih Tsai, Chih-Jen Wen, Chun-Liang Lo, Shiaw-Pyng Wey, Kun-Ju Lin,Tzu-Chen Yen, Ging-Ho Hsiu

Biomaterials (Elsevier) Taiwan, 22 December 2010

Biological Materials

Key words: Multifunctional hollow nanoparticles, Intracellular drug delivery, Cancer targeting, SPECT/CT imaging, Cancer therapy

1990
Crucial function of histone deacetylase 1 for differentiation of teratomas in mice and humans

Sabine Lagger, Dominique Meunier, Mario Mikula, Reinhard Brunmeir, Michaela Schlederer, Matthias Artaker, Oliver Pusch, Gerda Egger, Astrid Hagelkruys, Wolfgang Mikulits, Georg Weitzer, Ernst W Muellner, Martin Susani, Lukas Kenner, Christian Seiser

EMBO Journal (EMBO Press) Austria, 20 December 2010

Oncology

Key words: Cancer treatment chromatinepigeneticsHDAC inhibitorshistone modifications

1991
Lysophosphatidylcholine‐mediated functional inactivation of syndecan‐4 results in decreased adhesion and motility of dendritic cells

Johannes Bühligen, Mirko Himmel, Carl Gebhardt, Jan C Simon, Wolfgang Ziegler, Marco Averbeck

Journal of Cellular Physiology (Wiley) Germany, 15 December 2010

Cell Biology

1992
Loss of ATM/Chk2/p53 Pathway Components Accelerates Tumor Development and Contributes to Radiation Resistance in Gliomas

Massimo Squatrito, Cameron W Brennan, Karim Helmy, Jason T Huse, John H Petrini, Eric C Holland

Cancer Cell (Cell Press) USA, 13 December 2010

Oncology

Key words: Glioblastoma mutliforme, DNA-damage response, ionizing radiation in vivo

1993
Somatic Mutations throughout the Entire Mitochondrial Genome Are Associated with Elevated PSA Levels in Prostate Cancer Patients

Anita Kloss-Brandstätter, Georg Schäfer, Gertraud Erhart, Alexander Hüttenhofer, Stefan Coassin, Christof Seifarth, Monika Summerer, Jasmin Bektic, Helmut Klocker, Florian Kronenberg

American Journal of Human Genetics (Elsevier) Austria, 02 December 2010

Oncology

Key words: Somatic mitochondrial DNA (mtDNA) mutations, mitochondrial genes MT-CO2, MT-CO3, MT-ATP6, and MT-ND6, human mitochondrial genome

1994
Neuronal hyperexcitability and seizures are associated with changes in glial–neuronal interactions in the hippocampus of a mouse model of epilepsy with mental retardation

Torun Melø, Paolo Bigini, Ursula Sonnewald, Silvia Balosso, Alfredo Cagnotto, Sara Barbera, Sarah Uboldi, Annamaria Vezzani, Tiziana Mennini

Journal of Neurochemistry (Wiley) Norway, Italy, 19 November 2010

Neuroscience

Key words: 13C nuclear magnetic resonance spectroscopy, astrocytes and microglia, glutamate and GABA, hippocampus, neuronal ceroid lipofuscinosis, seizures

1995
Semi-automatic identification of punching areas for tissue microarray building: the tubular breast cancer pilot study

Federica Viti, Ivan Merelli, Mieke Timmermans, Michael den Bakker, Francesco Beltrame, Peter Riegman, Luciano Milanesi

BMC Bioinformatics (Springer) Italy, The Netherlands, 18 November 2010

Medical Image Analysis

Key words: Pixel Intensity, Pathological Region, Virtual Microscope, Donor Block, Unaffected Area

1996
Nuclear localization of Nm23-H1 in head and neck squamous cell carcinoma is associated with radiation resistance

Haeng Ran Park, Se-Heon Kim, Sei Young Lee, Ji Min Sung, Ae Ran Park, Suki Kang, Baek Gil Kim, Yoon Pyo Choi, Yong-Bae Kim, Nam Hoon Cho

Cancer (Wiley) South Korea, 18 November 2010

Oncology

Key words: Nm23-H1, nuclear localization, radiation resistance, head and neck squamous cell carcinoma, predictor

1997
p53 activation mediates polyglutamine-expanded ataxin-3 upregulation of Bax expression in cerebellar and pontine nuclei neurons

An-Hsun Chou, An-Chi Lin, Kue-Yi Hong, Su-Huei Hu, Ying-Ling Chen, Ju-Yu Chen, Hung-Li Wang

Neurochemistry International (Elsevier) Taiwan, 16 November 2010

Neuroscience

Key words: Spinocerebellar ataxia type 3, Polyglutamine-expanded ataxin-3, Cerebellum, Pontine nuclei, Bax,

1998
Standards and impact of hematopathology in myelodysplastic syndromes (MDS)

Peter Valent, Attilio Orazi, Guntram Büsche, Annette Schmitt-Gräff, Tracy I George, Karl Sotlar, Berthold Streubel, Christine Beham-Schmid, Sabine Cerny-Reiterer, Otto Krieger, Arjan van de Loosdrecht, Wolfgang Kern, Kiyoyuki Ogata, Friedrich Wimazal, Judit Csomor, Judit Varkonyi, Wolfgang R Sperr, Martin Werner, Hans Kreipe, Horny Hans-Peter

Oncotarget (Impact Journals) Austria, Germany, Hungary, USA, Japan, The Netherlands, 16 November 2010

Oncology

Key words: MDS, hematopathology, diagnostic criteria, prognostication

1999
The role of collagen receptors Endo180 and DDR-2 in the foreign body reaction against non-crosslinked collagen and gelatin

Qingsong Ye, Martin C Harmsen, Yijin Ren, Ruud A Bank

Biomaterials (Elsevier) The Netherlands, China, Australia, 10 November 2010

Biological Materials

Key words: Collagen, Gelatin, Endo180, DDR-2, Foreign body reaction, Giant cells

2000
Highly malignant intra-hepatic metastatic hepatocellular carcinoma in rats

Y Guo, R Klein, RA Omary, GY Yang, AC Larson

American Journal of Translational Research (e-Century Publishing Corporation) USA, 01 November 2010

Hepathology

Key words: Hepatocellular carcinoma (HCC), rodent model, orthotopic implantation, N1-S1 rat HCC cell line, McARH7777 rat HCC cell line, MRI, histopathology

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