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White papers
Integrative Multiomics Approach Unveils Systemic Dysfunction in Colorectal Cancer (CRC)
October, 2025
A recent study, published in Clinical and Translational Medicine, provides new insights into the colorectal cancer (CRC) immune macroenvironment, identifying key clinical biomarkers that could help stratify CRC patients for immune checkpoint inhibitor (ICI) therapies.
Advanced Imaging Reveals Why Some Breast Cancers Resist Treatment
September, 2025
Breast cancer continues to affect millions of people around the world—and for most, the diagnosis involves a hormone receptor-positive subtype.1
Epigenetic Carcinogenesis: Quantitative Insights from HistoQuest Analysis
May, 2025
The evolving understanding of cancer biology underscores the pivotal role of epigenetic modifications - heritable yet reversible changes in gene expression that do not alter the DNA sequence.
Association of PD-1+ Treg/PD-1+ CTL Ratio and TLS with Prognosis and Response in Advanced Gastric Cancer
April, 2025
Researchers used advanced imaging and analysis tools from TissueGnostics to detect and quantify two cell types, the PD-1+ regulatory T cells (Treg)/PD-1+CD8+ cytotoxic T cells (CTL) ratio, and tertiary lymphoid structure (TLS) presence in tumor tissue.
Improving the Efficacy of Immunotherapy in Lung Cancer Through Novel Target Discoveries
October, 2024
The researchers elucidated the role of the B7-H4 ligand in lung cancer, using spatial tissue cytometry solutions.
Multimodal Spatial Biology Approach Reveals a Novel Cancer-Associated Fibroblast (CAF) Subset in HNSCC
September, 2024
The team of scientists identified a new CAF subset in HNSCC combining tissue cytometry and spatial transcriptomics
Algorithmic automation of bone research with StrataQuest
July, 2024
A team from the Medical University of Vienna, Austria, developed an algorithm to automatically detect and quantify osteoclasts within StrataQuest image analysis software.
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