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Research powered by tissuegnostics
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White Papers

Please find a curated selection of research made possible by TissueGnostics software and systems below or in our searchable data base.

 
White Paper Role of PD-1+ Treg/PD-1+ CTL Ratio and Tertiary Lymphoid Structures in Gastric Cancer

Association of PD-1+ Treg/PD-1+ CTL Ratio and Tertiary Lymphoid Structures with Prognosis and Response in Advanced Gastric Cancer

April, 2025

Researchers used advanced imaging and analysis tools from TissueGnostics to detect and quantify two cell types, the PD-1+ regulatory T cells (Treg)/PD-1+CD8+ cytotoxic T cells (CTL) ratio, and tertiary lymphoid structure (TLS) presence in tumor tissue.

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White Paper Improving the Efficacy of Immunotherapy in Lung Cancer Through Novel Target Discoveries

Improving the Efficacy of Immunotherapy in Lung Cancer Through Novel Target Discoveries

October, 2024

The researchers elucidated the role of the B7-H4 ligand in lung cancer, using spatial tissue cytometry solutions.

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White Paper Multimodal Spatial Biology Approach Reveals a Novel Cancer-Associated Fibroblast (CAF) Subset in HNSCC

Multimodal Spatial Biology Approach Reveals a Novel Cancer-Associated Fibroblast (CAF) Subset in HNSCC

September, 2024

The team of scientists identified a new CAF subset in HNSCC combining tissue cytometry and spatial transcriptomics

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White Paper Algorithmic automation of bone research with StrataQuest

Algorithmic automation of bone research with StrataQuest

July, 2024

A team from the Medical University of Vienna, Austria, developed an algorithm to automatically detect and quantify osteoclasts within StrataQuest image analysis software.

Read more
White Paper Understanding Glioblastoma, One Cell at a Time

Understanding Glioblastoma, One Cell at a Time

June, 2024

Spatial transcriptomics and tissue cytometry can be synergistically combined to verify the results or deepen the understanding of TME processes both on mRNA and protein level

Read more
White Paper Analysis of Organoid and Immune Cell Co-Cultures By Machine Learning-Empowered Image Cytometry

Analysis of Organoid and Immune Cell Co-Cultures By Machine Learning-Empowered Image Cytometry

April, 2024

The StrataQuest Organoid App provides reliable and efficient high-throughput validation and quantification for organoids co-cultured alongside immune cells.

Read more
White Paper The Role of Cytolytic CD8+ T Cells in Suppressing Ongoing HIV Replication in Spontaneous Controller Lymph Node

The Role of Cytolytic CD8+ T Cells in Suppressing Ongoing HIV Replication in Spontaneous Controller Lymph Nodes

November, 2023

Using TissueGnostics’ tissue cytometry solutions, a recent study revealed important information on how sustained cytolytic CD8+ T cells are central in determining long-term viral control in lymph nodes (LNs). This further elucidates the mechanisms behind the immune control over cancerous diseases, which may be used to develope treatments strategies for more effective results and better patient outcomes.

Read more
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White Paper Role of PD-1+ Treg/PD-1+ CTL Ratio and Tertiary Lymphoid Structures in Gastric Cancer

Association of PD-1+ Treg/PD-1+ CTL Ratio and Tertiary Lymphoid Structures with Prognosis and Response in Advanced Gastric Cancer

April, 2025

Researchers used advanced imaging and analysis tools from TissueGnostics to detect and quantify two cell types, the PD-1+ regulatory T cells (Treg)/PD-1+CD8+ cytotoxic T cells (CTL) ratio, and tertiary lymphoid structure (TLS) presence in tumor tissue.

Read more
White Paper Improving the Efficacy of Immunotherapy in Lung Cancer Through Novel Target Discoveries

Improving the Efficacy of Immunotherapy in Lung Cancer Through Novel Target Discoveries

October, 2024

The researchers elucidated the role of the B7-H4 ligand in lung cancer, using spatial tissue cytometry solutions.

Read more
White Paper Multimodal Spatial Biology Approach Reveals a Novel Cancer-Associated Fibroblast (CAF) Subset in HNSCC

Multimodal Spatial Biology Approach Reveals a Novel Cancer-Associated Fibroblast (CAF) Subset in HNSCC

September, 2024

The team of scientists identified a new CAF subset in HNSCC combining tissue cytometry and spatial transcriptomics

Read more
White Paper Algorithmic automation of bone research with StrataQuest

Algorithmic automation of bone research with StrataQuest

July, 2024

A team from the Medical University of Vienna, Austria, developed an algorithm to automatically detect and quantify osteoclasts within StrataQuest image analysis software.

Read more
White Paper Understanding Glioblastoma, One Cell at a Time

Understanding Glioblastoma, One Cell at a Time

June, 2024

Spatial transcriptomics and tissue cytometry can be synergistically combined to verify the results or deepen the understanding of TME processes both on mRNA and protein level

Read more
White Paper Analysis of Organoid and Immune Cell Co-Cultures By Machine Learning-Empowered Image Cytometry

Analysis of Organoid and Immune Cell Co-Cultures By Machine Learning-Empowered Image Cytometry

April, 2024

The StrataQuest Organoid App provides reliable and efficient high-throughput validation and quantification for organoids co-cultured alongside immune cells.

Read more
White Paper The Role of Cytolytic CD8+ T Cells in Suppressing Ongoing HIV Replication in Spontaneous Controller Lymph Node

The Role of Cytolytic CD8+ T Cells in Suppressing Ongoing HIV Replication in Spontaneous Controller Lymph Nodes

November, 2023

Using TissueGnostics’ tissue cytometry solutions, a recent study revealed important information on how sustained cytolytic CD8+ T cells are central in determining long-term viral control in lymph nodes (LNs). This further elucidates the mechanisms behind the immune control over cancerous diseases, which may be used to develope treatments strategies for more effective results and better patient outcomes.

Read more
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BLOG UPDATE
An Introduction to Spatial Tissue Cytometry

Cytometry encompasses several methods for investigating cells, such as their count, cell cycle state, phenotype, morphology, size ...

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NEW Boxed Cytometer - Colubris

We have a lot of exciting plans to share for our big birthday, but we also have many important milestones to reflect on and remember...

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IHC IMMUNE SATUS IN SITU

The IHC Immune Status in Situ App uses the AI classifier to segment tissue into morphological entities such as tumor, stroma, and lymphocyte clusters. It further identifies single cells ...

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Nadine Bayer
TG ACADEMY WEBINAR
The Effect of Stem Cell Transplantation on Skin Microorganisms
Watch Webinar
Nadine Bayer, PhD
Medical University
of Vienna
Eurolab Article
ARTICLE
Spatial Tissue Cytometry: Success Stories - Eurolab Article

Read about tissue cytometry's potential in understanding the complexities of cell populations in the tissue environment

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