Customer Publications (A total of 2312 papers published)
Maternal Angiotensin Increases Placental Leptin in Early Gestation via an Alternative Renin-Angiotensin System Pathway: Suggesting a Link to Preeclampsia
Hypertension (American Heart Association) Austria, Germany, Norway, UK, 29 March 2021
Reproductive Medicine
Key words: Candesartan, Leptin, Oxygen, Respiration, Trophoblasts [more]
Organism: Human
Tissue: Placenta
Expression of CD9 on porcine lymphocytes and its relation to T cell differentiation and cytokine production
Developmental & Comparative Immunology (Elsevier) Austria, France, 27 March 2021
Immunology
Key words: Tetraspanin, CD9, Porcine, Lymphocyte, Memory [more]
Organism: Mouse
Tissue: Lymphoid Tissue
Aging imparts cell-autonomous dysfunction to regulatory T cells during recovery from influenza pneumonia
JCI Insight (The American Society for Clinical Investigation) USA, 22 March 2021
Aging
Key words: Aging, T Cells [more]
Organism: Mouse
Tissue: Lung
Pathological State: Influenza Infection, Pneumonia
Selective Denervation of the Facial Dermato-Muscular Complex in the Rat: Experimental Model and Anatomical Basis
Frontiers in Neuroanatomy (Frontiers Media S.A.) Austria, Switzerland, 22 March 2021
Neuroscience
Key words: Facial Nerve, Trigeminal Nerve, Motor-Sensory Control, Facial Muscles, Axon Quantification, Whole-Mount Staining [more]
Organism: Rat
Tissue: Nerves
Inhibition of vascular adhesion protein‐1 enhances the anti‐tumor effects of immune checkpoint inhibitors
Cancer Science (Japanese Cancer Association) Japan, Bangladesh, 18 March 2021
Oncology
Key words: CTLs, H2O2, ICIs, Immunosuppression, VAP‐1 Inhibitor [more]
Organism: Mouse
Tissue: Colon
Pathological State: Cancer
Peroxisome-driven ether-linked phospholipids biosynthesis is essential for ferroptosis
Cell Death & Differentiation (Nature) China, USA, 17 March 2021
Oncology
Key words: Cancer Metabolism, Phospholipids [more]
Organism: Human
Tissue: Kidney
Pathological State: Cancer
Luteolin Modulates the NF-E2-Related Factor 2/Glutamate–Cysteine Ligase Pathway in Rats with Spinal Cord Injury
Journal of Medicinal Food (Mary Ann Liebert Inc.) China, 16 March 2021
Neuroscience
Key words: Luteolin, Nrf2/GCL Pathway, Oxidative Stress, Spinal Cord Injury [more]
Organism: Rat
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Machine perfused donor kidneys as a source of human renal endothelial cells
American Journal of Physiology (APS Journals) The Netherlands, 15 March 2021
Nephrology
Key words: Kidney, Transplantation, Endothelial Cells, Machine Perfusion, Perfusate [more]
Organism: Human
Pathological State: Organ Transplantation
Cell Line: MP-PRECs
Genetic Drivers of Head and Neck Squamous Cell Carcinoma: Aberrant Splicing Events, Mutational Burden, HPV Infection and Future Targets
Genes (MDPI) South Africa, Greece, 15 March 2021
Oncology
Key words: Head and Neck Squamous Cell Carcinoma (HNSCC), Aberrant Splicing Events, Human Papillomavirus (HPV) Infection, Non-Coding RNA (ncRNA), Methylation, Mutational Burden [more]
Pathological State: Cancer, HPV Infection
A Novel ALDH2 Activator AD-9308 Improves Diastolic and Systolic Myocardial Functions in Streptozotocin-Induced Diabetic Mice
Antioxidants (MDPI) Taiwan, USA, 13 March 2021
Cardiology, Endocrinology
Key words: Diabetic Cardiomyopathy, 4-Hydroxy-2-Nonenal, Mitochondrial Aldehyde Dehydrogenase 2, AD-9308 [more]
Organism: Mouse
Tissue: Heart
Pathological State: Diabetes
MicroRNA-126 inhibits pathological retinal neovascularization via suppressing vascular endothelial growth factor expression in a rat model of retinopathy of prematurity
European Journal of Pharmacology (Elsevier) Taiwan, 13 March 2021
Pharmacology
Key words: miR-126, Retinal Pigment Epithelium Cells, Vascular Endothelial Growth Factor, Oxygen-Induced Retinopathy, Neovascularization, Rat [more]
Organism: Rat
Tissue: Eye
Pathological State: Retinopathy
N-Acetyl Cysteine Overdose Inducing Hepatic Steatosis and Systemic Inflammation in Both Propacetamol-Induced Hepatotoxic and Normal Mice
Antioxidants (MDPI) Taiwan, 12 March 2021
Hepathology
Key words: Acetaminophen Overdose, N-Acetyl Cysteine Overdose, Two Inbred Mouse Strains, Hepatic Inflammation, Systemic Inflammation, Microvesicular Steatosis [more]
Organism: Mouse
Tissue: Liver
Pathological State: Hepatic Steatosis, Systemic Inflammation
Dissecting pathways to thrombocytopenia in a mouse model of visceral leishmaniasis
Blood Advances (ASH Publications) UK, 12 March 2021
Immunology
Key words: Blood Platelets, Infections, Leishmania Donovani, Leishmaniasis, Visceral, Mice, Thrombocytopenia, Drug Clearance, Thrombopoietin, Spleen, Liver [more]
Organism: Mouse
Tissue: Liver
Pathological State: Leishmaniasis
CHPF Regulates the Aggressive Phenotypes of Hepatocellular Carcinoma Cells via the Modulation of the Decorin and TGF-β Pathways
Cancers (MDPI) Taiwan, 12 March 2021
Oncology
Key words: Hepatocellular Carcinoma, Tumor Microenvironment, Chondroitin Polymerizing Factor, Chondroitin Sulfate, Decorin [more]
Organism: Human
Tissue: Liver
Pathological State: Cancer
KLF4, Slug and EMT in Head and Neck Squamous Cell Carcinoma
Cells (MDPI) Austria, 12 March 2021
Oncology
Key words: TissueFaxs, TWIST, ZEB, SCC-25, FaDu, UPCI-SCC090 [more]
Organism: Human
Tissue: Mucosa
Pathological State: Cancer
Dietary Modification Alters the Intrarenal Immunologic Micromilieu and Susceptibility to Ischemic Acute Kidney Injury
Frontiers in Immunology (Frontiers Media S.A.) South Korea, 11 March 2021
Immunology, Nephrology
Key words: Diet, High-Salt Diet, High-Fat Diet, Acute Kidney Injury, Immunologic Micromilieu, Ischemia-Reperfusion Injury [more]
Organism: Mouse
Tissue: Kidney
Pathological State: Acute Kidney Injury
Genome-wide 5-hydroxymethylcytosine Profiling Analysis Identifies MAP7D1 as A Novel Regulator of Lymph Node Metastasis in Breast Cancer
Genomics, Proteomics & Bioinformatics (Elsevier) China, 11 March 2021
Proteomics, Oncology
Key words: 5-Hydroxymethylcytosine (5hmC), Breast Cancer, Lymph Node Metastasis, MAP7D1, Biomarker [more]
Organism: Human
Tissue: Breast, Lymphoid Tissue
Pathological State: Cancer
A first-in-human phase 0 clinical study of RNA interference–based spherical nucleic acids in patients with recurrent glioblastoma
Science Translational Medicine (AAAS) USA, 10 March 2021
Oncology
Organism: Human
Tissue: Brain
Pathological State: Cancer
Aurka loss in CD19+ B cells promotes megakaryocytopoiesis via IL-6/STAT3 signaling-mediated thrombopoietin production
Theranostics (Ivyspring International Publisher) China, Japan, 04 March 2021
Cell Biology
Key words: Aurora-A, Thrombopoietin, STAT3, IL-6, Megakaryocytopoiesis. [more]
Organism: Mouse
Tissue: Spleen
CHPF promotes malignancy of breast cancer cells by modifying syndecan-4 and the tumor microenvironment
American Journal of Cancer Research (e-Century Publishing Corporation) Taiwan, 01 March 2021
Oncology
Key words: Breast Cancer, Chondroitin Sulfate, CHPF, Tumor Microenvironment, Syndecan-4 [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
Akebia saponin D ameliorates metabolic syndrome (MetS) via remodeling gut microbiota and attenuating intestinal barrier injury
Biomedicine & Pharmacotherapy (Elsevier) China, USA, 27 February 2021
Gastroenterology
Organism: Mouse
Tissue: Small Intestine
Parathyroid hormone induces transition of myofibroblasts in arteriovenous fistula and increases maturation failure
Endocrinology (Oxford Academic) Taiwan, USA, 26 February 2021
Endocrinology
Key words: Arteriovenous Fistula (AVF), Fibrosis, Hemodialysis, Parathyroid Hormone (PTH) [more]
Organism: Mouse
Tissue: Peritoneum, Muscle
Gastric Enzyme Supplementation Inhibits Food Allergy in a BALB/c Mouse Model
Nutrients (MDPI) Austria, 26 February 2021
Allergy Research
Key words: Food Allergy, Gastric Enzymes, Gastric Acid Suppression, Systemic Allergic Response, Allergy Prevention [more]
Organism: Mouse
Tissue: Stomach
Genetic Background Effects on the Expression of an Odorant Receptor Gene
Frontiers in Cellular Neuroscience (Frontiers Media S.A.) Brazil, 25 February 2021
Neuroscience
Key words: DNA Methylation, Odorant Receptor Gene, Olfactory Receptor Gene, Genetic Background, Gene Expression, Single Nucleotide Polymorphism [more]
Organism: Mouse
Tissue: Nose
Regulation of pancreatic fibrosis by acinar cell-derived exosomal miR-130a-3p via targeting of stellate cell PPAR-γ
Journal of Inflammation Research (Dovepress) China, 24 February 2021
Gastroenterology
Key words: Pancreatitis, Exosomes, miR-130a-3p, Pancreatic Fibrosis, PPAR- γ [more]
Organism: Rat
Tissue: Pancreas
Pathological State: Pancreatitis
Pollen grain microscopic image classification using an ensemble of fine-tuned deep convolutional neural networks
International Conference on Pattern Recognition (Springer) Austria, UK, 21 February 2021
Machine Learning
Key words: Medical Image Analysis
Accuracy of HPV E6/E7 mRNA examination using in situ hybridization in diagnosing cervical intraepithelial lesions
Diagnostic Pathology (Springer) China, 19 February 2021
Pathology
Key words: Cervical Intraepithelial Neoplasia, CIN, Diagnostic Accuracy, E6/E7 mRNA, In Situ Hybridization [more]
Organism: Human
Tissue: Cervix
Pathological State: Cervical lesions
T cell-tropic HIV efficiently infects alveolar macrophages through contact with infected CD4+ T cells
Scientific Reports (Nature) USA, South Africa, UK, Germany, 16 February 2021
Virology
Key words: HIV Infections, Monocytes and Macrophages, Mucosal Immunology, Retrovirus, Virology, Virus–Host Interactions [more]
Organism: Human
Tissue: Lung
Pathological State: HIV infection
Imbalance of TGF-β1/BMP-7 pathways induced by M2-polarized macrophages promotes hepatocellular carcinoma aggressiveness
Molecular Therapy (Elsevier) China, 15 February 2021
Oncology
Organism: Human
Tissue: Liver
Pathological State: Cancer
Curcumin inhibits the growth of liver cancer by impairing myeloid‑derived suppressor cells in murine tumor tissues
Oncology Letters (Spandidos Publications) China, 12 February 2021
Oncology
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Insulin gene enhancer protein 1 mediates glycolysis and tumorigenesis of gastric cancer through regulating glucose transporter 4
Cancer Communications (Wiley) China, 11 February 2021
Oncology
Key words: Gastric Cancer, Glucose Transporter 4, Glycolysis, Insulin Gene Enhancer Protein 1, Tumorigenesis [more]
Organism: Human
Tissue: Stomach
Pathological State: Cancer
Global Analysis of Lysine Acetylome Reveals the potential role of CCL18 in non‐small cell lung cancer
Proteomics (Wiley) China, 11 February 2021
Proteomics
Key words: Acetylome, CCL18, Non-Small Cell Lung Cancer [more]
Organism: Human
Tissue: Lung
Pathological State: Cancer
Histone citrullination as a novel biomarker and target to inhibit progression of abdominal aortic aneurysms
Translational Research (Elsevier) Austria, UK, Sweden, 09 February 2021
Cardiology
Organism: Human
Tissue: Blood Vessels
Pathological State: Abdominal aortic aneurysms
IgG4 induces tolerogenic M2-like macrophages and correlates with disease progression in colon cancer
OncoImmunology (Taylor & Francis) Austria, Italy, UK, 08 February 2021
Oncology
Key words: IgG4, IgE, Tumor-Associated Macrophages, M2b, Allergooncology [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Anti-inflammatory effects of Radix aucklandiae herbal preparation ameliorate intestinal mucositis induced by 5-fluorouracil in mice
Journal of Ethnopharmacology (Elsevier) Taiwan, 07 February 2021
Pharmacology
Key words: 5-Fluorouracil (5-FU), Radix Aucklandiae, Intestinal Mucositis, Goblet Cell, Anti-Inflammatory [more]
Organism: Mouse
Tissue: Small Intestine
Pathological State: Intestinal Mucositis
Hiltonol Cocktail Kills Lung Cancer Cells by Activating Cancer-Suppressors, PKR/OAS, and Restraining the Tumor Microenvironment
International Journal of Molecular Sciences (MDPI) Taiwan, USA, Singapore, 05 February 2021
Oncology
Key words: NSCLC (Non-Small Cell Lung Cancer), Combinatorial Treatment with Hiltonol+++ Cocktail [Hiltonol+Anti-IL6+Stattic+AG490], Tumorigenic Microenvironment, Anti- and Pro-Tumorigenic Cytokine Production, Tumor-Suppressors PKR (Protein Kinase R) And OAS (2′5′ Oligoadenylate Synthetase) [more]
Organism: Human
Tissue: Lung
Pathological State: Cancer
H2S-mediated aerobic exercise antagonizes the hippocampal inflammatory response in CUMS-depressed mice.
Journal of Affective Disorders (Elsevier) China, 05 February 2021
Neuroscience
Key words: Chronic Stress Stimulated Depression Model, Hippocampus, Hydrogen Sulfide, Inflammatory, Aerobic Exercise [more]
Organism: Mouse
Tissue: Brain
Morphine acts on spinal dynorphin neurons to cause itch through disinhibition
Science Translational Medicine (AAAS) USA, UK, 03 February 2021
Neuroscience
Organism: Mouse
Tissue: Skin
Expression of chondroitin sulfate proteoglycan 4 (CSPG4) in melanoma cells is downregulated upon inhibition of BRAF
Oncology Reports (Spandidos Publications) Austria, 02 February 2021
Oncology
Organism: Human
Cell Line: Melanoma cells
Irreversible electroporation ablation overcomes tumor-associated immunosuppression to improve the efficacy of DC vaccination in a mice model of pancreatic cancer
OncoImmunology (Taylor & Francis) USA, 02 February 2021
Oncology
Key words: Irreversible Electroporation, Dendritic Cell Vaccine, Pancreatic Ductal Adenocarcinoma, Magnetic Resonance Imaging [more]
Organism: Mouse
Tissue: Pancreas
Pathological State: Cancer
iTRAQ-based Quantitative Proteomic Analysis of Dural Tissues Reveals Upregulated Haptoglobin to be a Potential Biomarker of Moyamoya Disease
Current Proteomics (ingentaconnect) China, 01 February 2021
Proteomics
Key words: Moyamoya Disease, Dura Mater, Proteomics, iTRAQ, Haptoglobin, Strokes
Nerve Fibers in the Tumor Microenvironment Are Co-Localized with Lymphoid Aggregates in Pancreatic Cancer
Journal of Clinical Medicine (MDPI) Germany, The Netherlands, UK, Austria, 30 January 2021
Oncology
Key words: Tumor Microenvironment, Machine Learning, Nerve Fiber Density, Spatial Arrangements, Tertiary Lymphoid Structures, Pancreatic Cancer [more]
Organism: Mouse
Tissue: Pancreas
Pathological State: Cancer
Endothelial-Derived miR-17∼ 92 Promotes Angiogenesis to Protect against Renal Ischemia-Reperfusion Injury
Journal of The American Society of Nephrology (Am Soc Nephrol) USA, 29 January 2021
Nephrology
Key words: microRNA, Acute Kidney Injury, Renal Microvasculature [more]
Pathological State: Acute Kidney Injury
Mer tyrosine kinase (MerTK) as a possible link between resolution of inflammation and tissue fibrosis in IgG4-related disease
Rheumatology (Oxford Academic) Italy, USA, Japan, 29 January 2021
Rheumatology
Key words: IgG4-Related Disease, Macrophages, MerTK, Protein S, Fibrosis [more]
Organism: Human
Tissue: Submandibular Gland, Pancreas
Pathological State: IgG4-Related Disease
Effects of Nicorandil on Inflammation, Apoptosis and Atherosclerotic Plaque Progression
Biomedicines (MDPI) Austria, 27 January 2021
Cardiology
Key words: Nicorandil, Inflammation, Apoptosis, Atherosclerosis, Plaque, Plaque Stabilization [more]
Organism: Mouse
Tissue: Blood Vessels
Pathological State: Atherosclerosis
Interleukin-24 protects against liver injury in mouse models
EBioMedicine (THE LANCET) Taiwan, 25 January 2021
Hepathology
Key words: Interleukin-24, Liver Fibrosis, Thioacetamide-Induced Liver Injury, Hepatic Stellate Cells [more]
Organism: Human
Tissue: Liver
Pathological State: Liver Fibrosis
Immune Modulation Effects of Lactobacillus casei Variety rhamnosus on Enterocytes and Intestinal Stem Cells in a 5-FU-Induced Mucositis Mouse Model
Gastroenterology Research and Practice (Hindawi Publishing Corporation) Taiwan, 25 January 2021
Gastroenterology
Organism: Mouse
Tissue: Small Intestine
Pathological State: Intestinal Mucositis
A Hepatitis B Virus-Derived Peptide Exerts an Anticancer Effect via TNF/iNOS-producing Dendritic Cells in Tumor-Bearing Mouse Model
Cancers (MDPI) South Korea, 22 January 2021
Oncology
Key words: HBV-Derived Poly6 Peptide, TNF/ iNOS-Producing DCs (Tip-DCs), Type 1 Interferon (IFN-I), CD40, Cancer Immunotherapy [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Androgen Plays a Carcinogenic Role in EOC via the PI3K/AKT Signaling Pathway in an AR-Dependent Manner
Journal of Cancer (Ivyspring International Publisher) China, 21 January 2021
Oncology
Key words: Ovarian Carcinoma, Androgen Receptor (AR), Tissue Microarray (TMA), Proliferation Promotion, PI3K/AKT Signalling Pathway [more]
Organism: Human
Tissue: Ovaries
Pathological State: Cancer
Performance and Meat Quality of Intrauterine Growth Restricted Pigs
Animals (MDPI) Poland, 20 January 2021
Zoology
Key words: IUGR, Pigs, Growth Performance, Meat Quality, Sensory Evaluation [more]
Organism: Pig
Tissue: Muscle
Pathological Pulmonary Vascular Remodeling is Induced by Type V Collagen in a Model of Scleroderma
Pathology-Research and Practice (Elsevier) Brazil, USA, 19 January 2021
Cardiology
Key words: Animal Model, Scleroderma, Collagen V, Vascular Disease, Endothelium [more]
Organism: Rabbit
Tissue: Lung
Pathological State: Scleroderma, Vascular Disease
Comparison of two fluorescent probes in preclinical non-invasive imaging and image-guided debridement surgery of Staphylococcal biofilm implant infections
Scientific Reports (Nature) USA, The Netherlands, 15 January 2021
Medical Imaging
Key words: Biofilms, Infectious Diseases [more]
Pathological State: Staphylococcus aureus Infection
PEG-GO@ XN nanocomposite suppresses breast cancer metastasis via inhibition of mitochondrial oxidative phosphorylation and blockade of epithelial-to …
European Journal of Pharmacology (Elsevier) China, USA, 14 January 2021
Oncology, Nanomedicine
Key words: Graphene Oxide, Xanthohumol, Breast Cancer Metastasis, Mitochondria, Epithelial-Mesenchymal Transition, Energy Metabolism [more]
Organism: Mouse
Tissue: Lung
Pathological State: Cancer
Macromolecular crowding as a tool to screen anti-fibrotic drugs: the Scar-in-a-Jar system revisited
Frontiers in Medicine (Frontiers Media S.A.) The Netherlands, China, USA, Switzerland, 14 January 2021
Biological Methods
Key words: Macromolecular Crowding, Drug Testing, Fibrosis, Collagen, Myofibroblast [more]
Organism: Human
Cell Line: adult primary human dermal fibroblasts
Mesenchymal stem cell‐glioblastoma interactions mediated via kinin receptors unveiled by cytometry
Cytometry Part A (Wiley) Brazil, 13 January 2021
Medical Image Analysis
Key words: Cytometry, Glioblastoma, Kinin Receptors, Kinin‐B1 Receptor, Kinin‐B2 Receptor, Mesenchymal Stem Cells [more]
Organism: Human
Cell Line: Glioblastoma (U87) cells, Mesenchymal stem cell
Overexpression of neuregulin 1 in GABAergic interneurons results in reversible cortical disinhibition
Nature Communications (Nature) China, 12 January 2021
Neuroscience
Key words: Molecular Neuroscience, Schizophrenia [more]
Organism: Mouse
Tissue: Brain
Stem Cell-Derived Respiratory Epithelial Cell Cultures as Human Disease Models
American Journal of Respiratory Cell and Molecular Biology (Wiley) UK, 11 January 2021
Stem Cell Research
Key words: Respiratory Epithelium, Epithelial Cells, Cell Culture, Cloning, Stem Cells
Overexpression of GLUT3 promotes metastasis of triple‐negative breast cancer by modulating the inflammatory tumor microenvironment
Journal of Cellular Physiology (Wiley) Taiwan, 09 January 2021
Oncology
Key words: Glycolysis, Inflammation, Triple‐Negative Breast Cancer, Tumor Microenvironment, Tumor‐Associated Macrophage [more]
Organism: Mouse
Tissue: Lung
Pathological State: Cancer
Development and Validation of Sorafenib-eluting Microspheres to Enhance Therapeutic Efficacy of Transcatheter Arterial Chemoembolization in a Rat Model of of Hepatocellular Carcinoma
Radiology: Imaging Cancer (Royal Society of Chemistry) USA, 08 January 2021
Oncology
Organism: Rat
Tissue: Liver
Pathological State: Cancer
Persistence of mature dendritic cells, TH2A, and Tc2 cells characterize clinically resolved atopic dermatitis under IL-4Rα blockade
Science Immunology (Science) Austria, 08 January 2021
Immunology, Dermatology
Organism: Human
Tissue: Skin
Pathological State: Dermatitis
Differential expression of microRNA miR-150-5p in IgA nephropathy as a potential mediator and marker of disease progression.
Kidney International (Elsevier) UK, Canada, Germany, Spain, 06 January 2021
Nephrology
Key words: IgA Nephropathy, microRNA [more]
Organism: Human
Tissue: Kidney
Pathological State: IgA nephropathy
Hypoxia-induced suppression of alternative splicing of MBD2 promotes breast cancer metastasis via activation of FZD1
Cancer Research (AACR Publications) China, USA, 05 January 2021
Oncology
Stressed erythrophagocytosis induces immunosuppression during sepsis through heme-mediated STAT1 dysregulation
The Journal of Clinical Investigation (American Society of Clinical Investigation) USA, 04 January 2021
Immunology
Organism: Mouse
Tissue: Liver
IN VITRO CHARACTERIZATION OF HYDROXYAPATITE-BASED BIOMATERIALS, USING MESENCHYMAL STEM CELL CULTURES FROM HUMAN BONE …
Journal of Science and Arts (Josa.ro) Romania, 30 December 2020
Biological Materials
Key words: Hydroxyapatite, Calcium Fructoborate, Mesenchymal Stem Cell, Human Bone Marrow [more]
Organism: Human
Cell Line: Mesenchymal stem cells
Persistent inhibition of Candida albicans biofilm and hyphae growth on titanium by graphene nanocoating
Dental Materials (Elsevier) Singapore, USA, UK, 25 December 2020
Biological Materials
Key words: Implant, Surface Free Energy, Contact Angle, Topography, Microbial Attachment, Antiadhesive Coating, Peri-Implantitis [more]
Cell Line: C. albicans
Obesity is associated with shorter telomere length in prostate stromal cells in men with aggressive prostate cancer
Cancer Prevention Research (AACR Publications) USA, 22 December 2020
Oncology
PD‐L1+ dendritic cells in the tumor microenvironment correlate with good prognosis and CD8+ T cell infiltration in colon cancer
Cancer Science (Wiley) Australia, 20 December 2020
Oncology
Key words: CD8, Colon Cancer, Dendritic Cells, PD‐L1, T Cells
Heterogeneous Tumor-Immune Microenvironments between Primary and Metastatic Tumors in a Patient with ALK Rearrangement-Positive Large Cell Neuroendocrine Carcinoma
International Journal of Molecular Sciences (MDPI) Japan, USA, 19 December 2020
Oncology
Key words: Anaplastic Lymphoma Kinase (ALK), B Cell, Heterogeneity, Immune Checkpoint, Large Cell Neuroendocrine Carcinoma (LCNEC), Neuroendocrine Tumors (NET), Regulatory T-Cells (Tregs), Programmed Death-Ligand 1 (PD-L1), Tumor-Infiltrating Lymphocyte (TIL), Tumor-Immune Microenvironments (TIME) [more]
Organism: Human
Tissue: Lung
Pathological State: Cancer
Parp1-Dependent DNA Double-Strand Break Repair in Irradiated Late Pachytene Spermatocytes
DNA and Cell Biology (Mary Ann Liebert Inc.) Saudi Arabia, Egypt, Germany, 18 December 2020
Reproductive Medicine
Key words: Alternative NHEJ, DNA Repair, First Meiotic Prophase, γ-H2AX, Homologous Recombination, Parp1, Spermatogenesis [more]
Organism: Human
Cell Line: Spermatocytes
Differential mast cell phenotypes in benign versus cancer tissues and prostate cancer oncologic outcomes
The Journal of Pathology (Wiley) USA, 18 December 2020
Oncology
Key words: Prostate Cancer, Mast Cells, Metastases, CXCR4, TFE3, KIT, Microenvironment [more]
Organism: Human
Tissue: Prostate
Pathological State: Cancer
ZFHX3 Knockdown Dysregulates Mitochondrial Adaptations to Tachypacing in Atrial Myocytes through Enhanced Oxidative Stress and Calcium Overload
Acta Physiologica (Wiley) Taiwan, Japan, 17 December 2020
Physiology
Key words: Atrial Fibrillation, Calcium, Mitochondria, Tachypacing, ZFHX3 [more]
Organism: Human
Cell Line: HL‐1 cells
CD4+ CTLs in Fibrosing Mediastinitis Linked to Histoplasma capsulatum
The Journal of Immunology (American Association of Immunologists) Canada, Saudi Arabia, Japan, USA, 16 December 2020
Immunology
Organism: Human
Tissue: Mediastinum
Pathological State: Mediastinitis
Tribbles Pseudokinase 3 Contributes to Cancer Stemness of Endometrial Cancer Cells by Regulating β-Catenin Expression
Cancers (MDPI) Taiwan, 15 December 2020
Oncology
Key words: Tribbles Pseudokinase 3, Endometrial Cancer, Cancer Stem Cells, β-Catenin, Epithelial–Mesenchymal Transition [more]
Organism: Human
Cell Line: Endometrial Cancer Cell Lines (AN3CA and HEC1A)
Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer's Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals
Cell Systems (Cell Press) USA, Japan, 15 December 2020
Neuroscience
Key words: Alzheimer's Diseasea, Myloid Beta, Synaptic Dysfunction, Presynapse, Synaptic Vesicles, Proteostasis, Mass Spectrometry, Proteomics, APP Knockin Mice [more]
Organism: Mouse
Tissue: Brain
Pathological State: Alzheimer's Disease
Multicohort Retrospective Validation of a Predictive Biomarker for Topoisomerase I Inhibitors
Clinical Colorectal Cancer (Elsevier) USA, Japan, Australia, 10 December 2020
Oncology
Organism: Human
Tissue: Stomach
Pathological State: Cancer
Spatiotemporal Up-Regulation of Mu Opioid Receptor 1 in Striatum of Mouse Model of Huntington's Disease Differentially Affecting Caudal and Striosomal Regions
Frontiers in Neuroanatomy (Frontiers Media S.A.) USA, Japan, 10 December 2020
Neuroscience
Key words: Mu Opioid Receptors, Huntington’s Disease, Neostriatum, Movement Disorders, Mood Disorders, Animal Models of Human Disorders, Striosome [more]
Organism: Mouse
Tissue: Brain
Pathological State: Huntington's Disease
Bioinstructive Micro-Nanotextured Zirconia Ceramic Interfaces for Guiding and Stimulating an Osteogenic Response In Vitro
Nanomaterials (MDPI) Romania, 09 December 2020
Nanomedicine
Key words: Zirconia, Mesenchymal Stem Cells, Micro-Nano Topography, Osteogenic Differentiation, Bone-Anchored Hearing Aid (BAHA) [more]
Organism: Human
Cell Line: hMSCs
The effect of dietary supplementation with high-or low-dose omega-3 fatty acid on inflammatory pathology after traumatic brain injury in rats
Translational Neuroscience (degruyter) USA, 09 December 2020
Neuroscience
Key words: Dietary Supplementation, Docosahexanoic Acid, Eicosapentaenoic Acid, Neuroinflammation, Neuroprotection, Omega-3 Fatty Acid, Traumatic Brain Injury [more]
Organism: Rat
Tissue: Brain
Pathological State: Traumatic Brain Injury
Hypomethylation of PlncRNA-1 promoter enhances bladder cancer progression through the miR-136-5p/Smad3 axis
Cell Death & Disease (Nature) China, 07 December 2020
Oncology
Key words: Bladder Cancer, Long Non-Coding RNAs, Oncogenesis [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Integrative single-cell transcriptome analysis reveals a subpopulation of fibroblasts associated with favorable prognosis of liver cancer patients
Translational Oncology (Elsevier) China, 06 December 2020
Oncology
Key words: Liver Cancer, Single-Cell Transcriptome, Cancer-Distinct Fibroblast, SPARCL1 [more]
Organism: Human
Tissue: Liver
Pathological State: Cancer
Lactic acidosis interferes with toxicity of perifosine to colorectal cancer spheroids: multimodal imaging analysis
Frontiers in Oncology (Frontiers Media S.A.) Czech Republic, Switzerland, China, 04 December 2020
Oncology
Key words: Perifosine, Akt Kinase, Tumor Environment, Lactic Acidosis, Alkalization, Signal Co-Registration, Mass Spectrometry Imaging, Colorectal Cancer [more]
Organism: Human
Cell Line: HT-29 and HCT-116 cells
AC Pulsed Field Ablation Is Feasible and Safe in Atrial and Ventricular Settings: A Proof-of-Concept Chronic Animal Study
Frontiers in Bioengineering and Biotechnology (Frontiers Media S.A.) Czech Republic, France, Poland, Germany, 03 December 2020
Cardiology
Key words: Pulsed Field Ablation, Irreversible Electroporation (IRE), Radiofrequency Ablation, Atrial Fibrillation, Ventricular Arrhythmia (VA), Preclinical Cardiology [more]
Organism: Pig
Tissue: Heart
Shear stress-exposed pulmonary artery endothelial cells fail to upregulate HSP70 in chronic thromboembolic pulmonary hypertension
PLoS One (PLOS) Brazil, 03 December 2020
Cardiology
Key words: Shear Stresses, Endothelial Cells, Heat Shock Response, Pulmonary Arteries, Peas, Flow Cytometry, Nitric Oxide, Pulmonary Hypertension [more]
Organism: Human
Pathological State: Pulmonary hypertension
Cell Line: HPAECs
Infiltration of metastatic lymph nodes with PD-1+ T cells is associated with improved disease-free and overall survival in resected N+ NSCLC
American Journal of Cancer Research (e-Century Publishing Corporation) China, USA, 01 December 2020
Oncology
Key words: NSCLC, Metastatic Lymph Node, T Cell Subsets, PD-1, TIM-3 [more]
Organism: Human
Tissue: Lung
Pathological State: Cancer
The predictive power of CD3+ T cell infiltration of oral squamous cell tumors is limited to non-diabetic patients
Cancer Letters (Elsevier) Germany, 01 December 2020
Oncology
Key words: OSCC, Diabetes Mellitus, TIL, Metabolism, Prognosis [more]
Organism: Human
Pathological State: Cancer
p21‐activated kinase 4 promotes the progression of esophageal squamous cell carcinoma by targeting LASP1
Molecular Carcinogenesis (Wiley) China, 01 December 2020
Oncology
Key words: Cell Proliferation, Esophageal Squamous Cell Carcinoma, LASP1, Metastasis, PAK4 [more]
Organism: Human
Tissue: Esophagus
Pathological State: Cancer
Cross-Reactive Effects of Vaccines: Heterologous Immunity between Tetanus and Chlamydia
Vaccines (MDPI) Serbia, Austria, 01 December 2020
Immunology
Key words: Vaccination, Heterologous Immunity, Antibodies, Tetanus, Chlamydia, Cross-Reactivity [more]
Organism: Human
Cell Line: Human conjunctival epithelial cell line
Levodopa Improves Cognitive Function and the Deficits of Structural Synaptic Plasticity in Hippocampus Induced by Global Cerebral Ischemia/Reperfusion Injury in Rats
Frontiers in Neuroscience (Frontiers Media S.A.) China, 30 November 2020
Neuroscience
Key words: Levodopa, Hippocampus, Global Cerebral Ischemia Reperfusion Injury, Structural Synaptic Plasticity, Cognitive Function [more]
Organism: Rat
Tissue: Brain
Pathological State: Cerebral Ischemia
Characterization of epithelial cells, connective tissue cells and immune cells in human upper airway mucosa by immunofluorescence multichannel image cytometry: a pilot study
Histochemistry and Cell Biology (Springer) Austria, 29 November 2020
Medical Image Analysis
Key words: Image Cytometry, Fluorescent Antibody Technique, Immunohistochemistry, Nasal Mucosa, Sinusitis [more]
Organism: Human
Tissue: Mucosa
Pathological State: Chronic Rhinosinusitis
MicroRNA-146a suppresses tumor malignancy via targeting vimentin in esophageal squamous cell carcinoma cells with lower fibronectin membrane assembly
Journal of Biomedical Science (BMC) Taiwan, 28 November 2020
Oncology
Key words: ESCC, MiR-146a, Vimentin, Cell Migration, Invasion [more]
Organism: Human
Tissue: Esophagus
Pathological State: Cancer
Lactobacillus Attenuate the Progression of Pancreatic Cancer Promoted by Porphyromonas Gingivalis in K-rasG12D Transgenic Mice
Cancers (MDPI) Taiwan, 26 November 2020
Oncology
Key words: Caerulein, Lactobacillus, Pancreatic Ductal Adenocarcinoma, Porphyromonas Gingivalis, Transforming Growth Factor-β [more]
Organism: Human
Tissue: Pancreas
Pathological State: Cancer
Visfatin Enhances Breast Cancer Progression through CXCL1 Induction in Tumor-Associated Macrophages
Cancers (MDPI) Taiwan, UK, 26 November 2020
Oncology
Key words: Visfatin, Breast Cancer, Tumor-Associated Macrophages, CXCL1 [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
Nrf2 knockout altered brain iron deposition and mitigated age-related motor dysfunction in aging mice
Free Radical Biology and Medicine (Elsevier) China, 26 November 2020
Neuroscience
Key words: Nrf2, Motor Dysfunction, Brain Iron Metabolism, Oxidative Stress, FPN1 [more]
Organism: Mouse
Tissue: Brain
Neuropathology changed by 3-and 6-months low-level PM 2.5 inhalation exposure in spontaneously hypertensive rats
Particle and Fibre Toxicology (Springer) Taiwan, 26 November 2020
Neuroscience
Key words: Air Pollution, Autophagy, Central Nervous System Toxicity, Particulate Matter, Tau [more]
Organism: Rat
Tissue: Brain
Electric Pulse Responsive Magnetic Nanoclusters Loaded with Indoleamine 2, 3-Dioxygenase Inhibitor for Synergistic Immuno-Ablation Cancer Therapy
ACS Applied Materials & Interfaces (ACS Publications) USA, 25 November 2020
Oncology
Key words: Local Ablation, Irreversible Electroporation, Indoleamine 2, 3-Dioxygenase Inhibitor, Magnetic Nanoparticles, Immunotherapy [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Development of Rift valley fever encephalitis in rats is mediated by early infection of olfactory epithelium and neuroinvasion across the cribriform plate
Journal of General Virology (Microbiology Society) USA, 24 November 2020
Virology
Key words: Aerosol, Cribriform Plate, Encephalitis, Olfactory Bulb, Pathogenesis, Rift Valley Fever Virus [more]
Organism: Rat
Tissue: Mucosa
Pathological State: Encephalitis
Time-resolved analysis of Staphylococcus aureus invading the endothelial barrier
Virulence (Taylor & Francis) The Netherlands, 22 November 2020
Microbiology
Key words: Staphylococcus Aureus, MRSA, Endothelium, Invasion, Intracellular [more]
Organism: Human
Cell Line: HUVECs
Type II natural killer T cells contribute to protection against systemic methicillin-resistant Staphylococcus aureus infection
Frontiers in Immunology (Frontiers Media S.A.) USA, 18 November 2020
Immunology
Key words: Staphylococcus Aureus, Natural Killer T Cells, CD1, Lipid Antigens, Cytokine, Knockout Mice [more]
Organism: Mouse
Tissue: Kidney
Pathological State: Staphylococcus aureus Infection
Long-term skin-resident memory T cells proliferate in situ and are involved in human graft-versus-host disease
Science Translational Medicine (AAAS) Austria, 18 November 2020
Dermatology
Organism: Human
Tissue: Skin
Pathological State: Graft-versus-host disease
Correlation Between Early Plasma Interleukin 37 Responses With Low Inflammatory Cytokine Levels and Benign Clinical Outcomes in Severe Acute Respiratory Syndrome Coronavirus 2 Infection
The Journal of Infectious Diseases (Oxford Academic) China, 17 November 2020
SARS-CoV-2
Key words: IL-37, SARS-CoV-2, COVID-19, Inflammation, Clinical Outcomes [more]
Organism: Mouse
Tissue: Lung
Pathological State: COVID-19
Deviant reporter expression and P2X4 passenger gene overexpression in the soluble EGFP BAC transgenic P2X7 reporter mouse model
Scientific Reports (Nature) Germany, Ireland, 16 November 2020
Neuroscience
Key words: Biological Techniques, Molecular Biology, Neuroscience [more]
Organism: Mouse
Tissue: Brain
HCN channels in the mammalian cochlea: Expression pattern, subcellular location, and age‐dependent changes
Journal of Neuroscience Research (Wiley) Austria, 12 November 2020
Neuroscience
Key words: Auditory Development, Auditory Neuron Diversity, Axon Initial Segment, HCN Channels, Prestin, RRID:AB_90725, RRID:AB_2039906, RRID:AB_2302038, RRID:AB_2313584, RRID:AB_2313726, RRID:AB_2336419, RRID:AB_2336420, RRID:AB_2336790, RRID:AB_2340477, RRID:AB_2340452, RRID:AB_2340593, RRID:AB_2341028, RRID:AB_2617143, RRID:AB_2756625, RRID:AB_2756742, RRID:SCR_002865, RRID:SCR_013652, RRID:SCR_014823, Sound Coding, Spiral Ganglion Neurons, Voltage Gated [more]
Organism: Mouse, Human
Inhibition of aquaporin-3 in macrophages by a monoclonal antibody as potential therapy for liver injury
Nature Communications (Nature) Japan, USA, 09 November 2020
Hepathology
Key words: Molecular Drug Discovery, Liver Diseases, Molecular Medicine [more]
Organism: Mouse
Tissue: Bone Marrow
Pathological State: Liver Injury
CO2-Responsive Water-Soluble Conjugated Polymers for In Vitro and In Vivo Biological Imaging
Biomacromolecules (ACS Publications) Taiwan, 06 November 2020
Medical Imaging
Organism: Zebrafish
Tissue: Whole Organism
Mucus production stimulated by IFN-AhR signaling triggers hypoxia of COVID-19
Cell Research (Nature) China, 06 November 2020
Immunology, SARS-CoV-2
Key words: Immunology, Innate Immunity [more]
Organism: Mouse
Tissue: Lung
Pathological State: Covid-19
Evidence for a non-stochastic two-field hypothesis for persistent skin cancer risk
Scientific Reports (Nature) USA, 05 November 2020
Oncology
Key words: Cancer Microenvironment, Cancer Models, Skin Cancer, Squamous Cell Carcinoma [more]
Organism: Mouse
Tissue: Skin
Pathological State: Cancer
Human placental cell line HTR-8/SVneo accumulates cadmium by divalent metal transporters DMT1 and ZIP14
Metallomics (Royal Society of Chemistry) Austria, 04 November 2020
Reproductive Medicine
Organism: Human
Tissue: Placenta
Metformin chlorination byproducts in drinking water exhibit marked toxicities of a potential health concern
Environment International (Elsevier) China, 03 November 2020
Toxicology
Key words: Metformin, Metformin Chlorination Byproduct, Drinking Water, Toxicity, Public Health [more]
Organism: Mouse
Tissue: Small Intestine
Effect of route of administration on the efficacy of dendritic cell vaccine in PDAC mice
American Journal of Cancer Research (e-Century Publishing Corporation) USA, 01 November 2020
Oncology
Key words: Pancreatic Cancer, Dendritic Cell, Route of Administration [more]
Organism: Mouse
Tissue: Pancreas
Pathological State: Cancer
Therapeutic Efficacy of GC1118, a Novel Anti-EGFR Antibody, against Glioblastoma with High EGFR Amplification in Patient-Derived Xenografts
Cancers (MDPI) South Korea, 31 October 2020
Oncology
Key words: Glioblastoma, Epidermal Growth Factor Receptor, Monoclonal, Xenograft, Amplification [more]
Organism: Mouse
Tissue: Brain
Pathological State: Cancer
P2Y2 receptor activation promotes esophageal cancer cells proliferation via ERK1/2 pathway
European Journal of Pharmacology (Elsevier) Brazil, USA, South Africa, 31 October 2020
Oncology
Key words: Esophageal Cancer, Purinergic System, Nucleotide, P2Y2R, Proliferation, Signaling Pathways [more]
Organism: Human
Tissue: Esophagus
Pathological State: Cancer
Calenduloside E suppresses calcium overload by promoting the interaction between L-type calcium channels and Bcl2-associated athanogene 3 to alleviate myocardial ischemia–reperfusion injury
Journal of Advanced Research (Elsevier) China, 31 October 2020
Cardiology
Key words: Calenduloside E, Myocardial Ischemia-Reperfusion Injury, L-Type Calcium Channelscalcium Overload, Bcl2-Associated Athanogene 3 [more]
Organism: Rat
Tissue: Heart
Pathological State: Myocardial Ischemia
B Cell Activating Factor (BAFF) Is Required for the Development of Intra-Renal Tertiary Lymphoid Organs in Experimental Kidney Transplantation in Rats
International Journal of Molecular Sciences (MDPI) Germany, 28 October 2020
Nephrology
Key words: Tertiary Lymphoid Organs, Kidney Transplantation, B Cells, BAFF [more]
Organism: Rat
Tissue: Kidney
Pathological State: Organ Transplantation
Proteomics of regenerated tissue in response to a titanium implant with a bioactive surface in a rat tibial defect model
Scientific Reports (Nature) Romania, 28 October 2020
Osteology
Key words: Bioinformatics, Biological Models, Fracture Repair, Immunological Techniques, Mass Spectrometry, Microscopy, Proteomic Analysis [more]
Organism: Human
Cell Line: Human mesenchymal stem cells (hMSCs)
Characterization of Negative Allosteric Modulators of the Calcium-Sensing Receptor for Repurposing as a Treatment of Asthma
The Journal of Pharmacology and Experimental Therapeutics (ASPET) UK, Austria, Australia, 28 October 2020
Pharmacology
Organism: Mouse
Tissue: Lung
Striosomes Mediate Value-Based Learning Vulnerable in Age and a Huntington's Disease Model
CELL (Cell Press) USA, 27 October 2020
Neuroscience
Key words: Corticostriatal, Approach-Avoidance, Cost-Benefit, Decision-Making, Utility, Subjective Value, Motivation, Parvalbumin Interneurons, VGluT1, Excitation-Inhibition Balance [more]
Organism: Mouse
Tissue: Brain
Pathological State: Huntington's Disease
The Immune Phenotype of Isolated Lymphoid Structures in Non-Tumorous Colon Mucosa Encrypts the Information on Pathobiology of Metastatic Colorectal Cancer
Cancers (MDPI) Austria, Switzerland, 25 October 2020
Oncology
Key words: Lymphoid Structures, Colonic Mucosa, Metastatic Colorectal Cancer, Immuno-Oncology, B Lymphocytes, Germinal Center, Tissue Image Cytometry, B-Cell Clonality, Compendium-Wide Analysis, Patient Stratification Strategy [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Cross‐section modified and highly elastic sutures reduce tissue incision and show comparable biocompatibility: in‐vitro and in‐vivo evaluation of novel thermoplastic urethane surgical threads
Journal of Biomedical Materials Research: Part B (Wiley) Germany, 24 October 2020
Tissue Engineering
Key words: Animal Trials, Biocompatibility, Elastic Sutures, Surface Modified Surgical Threads, Thermoplastic Polyurethane, Tissue Incision [more]
Organism: Rat
Tissue: Stomach
Direct signaling of TL1A-DR3 on fibroblasts induces intestinal fibrosis in vivo
Scientific Reports (Nature) USA, 23 October 2020
Immunology, Gastroenterology
Key words: Cytokines, Gastroenterology, Immunology, Inflammation, Inflammatory Bowel Disease [more]
Organism: Mouse
Cell Line: Mouse primary colonic fibroblasts
Increased Radiation-Associated T-Cell Infiltration in Recurrent IDH-Mutant Glioma
International Journal of Molecular Sciences (MDPI) Germany, 21 October 2020
Neuroscience
Key words: Lower-Grade Glioma, T-Cell Infiltration, TissueFAXS, Primary Tumors, Recurrent Tumors, Radiotherapy [more]
Organism: Human
Tissue: Brain
Pathological State: Cancer
Impaired autophagy increases susceptibility to endotoxin-induced chronic pancreatitis
Cell Death & Disease (Nature) Germany, 21 October 2020
Gastroenterology
Key words: Acute Pancreatitis, Chronic Pancreatitis [more]
Organism: Mouse
Tissue: Pancreas
Pathological State: Pancreatitis
Tissue remodeling macrophages morphologically dominate at the interface of polypropylene surgical meshes in the human abdomen
Hernia (Springer) Germany, UK, 18 October 2020
Tissue Engineering
Key words: Foreign Body Reaction, Macrophage, Collagen, Mesh, Fluorescence Microscopy [more]
Organism: Mouse
Tissue: Stomach
CDK5 Inhibition Abrogates TNBC Stem‐Cell Property and Enhances Anti‐PD‐1 Therapy
Advanced Science (Wiley) China, 15 October 2020
Oncology
Key words: Cancer Stem Cells, CD44 Variants, CDK5, Immune Checkpoint Blockade, PPARγ Phosphorylation, Triple‐Negative Breast Cancer, Tumor Microenvironment [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
Poly (ADP-ribose) polymerase inhibitor treatment as a novel therapy attenuating renal ischemia-reperfusion injury
Frontiers in Immunology (Frontiers Media S.A.) South Korea, Italy, France, 14 October 2020
Immunology
Key words: Acute Kidney Injury, Ischemia-Reperfusion Injury, Poly(ADP-Ribose) Polymerase (PARP) Inhibitor, Parthanatos, Inflammation, Translational Immunology [more]
Organism: Mouse
Tissue: Kidney
Pathological State: Acute Kidney Injury
Two Polyurethane Adhesives for PVDF Fixation Show Superior Biocompatibility in a Rat Model
Journal of Investigative Surgery (Taylor & Francis) Germany, The Netherlands, 14 October 2020
Tissue Engineering
Key words: Mesh Fixation, Polyurethane Adhesive, Incisional Hernia [more]
Organism: Rat
Tissue: Stomach
FATS regulates polyamine biosynthesis by promoting ODC degradation in an ERβ-dependent manner in non-small-cell lung cancer
Cell Death & Disease (Nature) China, 09 October 2020
Oncology
Key words: Apoptosis, Macroautophagy [more]
Organism: Human
Cell Line: Human NSCLC cell lines (A549, H520, H358, H460, H1299 and U87)
Immune contexture analysis in immuno‐oncology: applications and challenges of multiplex fluorescent immunohistochemistry
Clinical & Translational Immunology (Wiley) Australia, 07 October 2020
Immunology
Key words: FCS Express Image Cytometry, Immune Profiling, Multiplexed Fluorescent Immunohistochemistry, Quantitative Digital Pathology, Tumor Microenvironment, Vectra
Prenatal smoke exposure dysregulates lung epithelial cell differentiation in mouse offspring: role for AREG-induced EGFR signaling
APSselect (American Physiological Society) The Netherlands, Mongolia, Germany, China, 06 October 2020
Pulmonology
Key words: Amphiregulin, Epithelial Cell Differentiation, Lung Organoids, Prenatal Smoke Exposure [more]
Organism: Mouse
Tissue: Lung
Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during clinical latency
Nature Communications (Nature) Germany, Switzerland, 05 October 2020
Oncology
Key words: Breast Cancer, Cancer [more]
Organism: Mouse
Tissue: Breast
Pathological State: Cancer
Innovations present in the primate interneuron repertoire
Nature (Nature) USA, 30 September 2020
Neuroscience
Key words: Evolutionary Biology, Genetics of The Nervous System, Transcriptomics [more]
Organism: Marmoset
Tissue: Brain
Peptide-Based TNF-α-Binding Decoy Therapy Mitigates Lipopolysaccharide-Induced Liver Injury in Mice
Pharmaceuticals (MDPI) Taiwan, 29 September 2020
Hepathology
Key words: TNF-α, Necroptosis, Pyroptosis, Apoptosis, Autophagy, Mitochondrial Injury [more]
Organism: Mouse
Tissue: Liver
Prothymosin α activates type I collagen to develop a fibrotic placenta in gestational diabetes
Clinical Science (Portland Press) Taiwan, UK, 25 September 2020
Endocrinology
Key words: Fibrosis, Gestational Diabetes, Placenta, Prothymosin α, Trophoblast [more]
Pathological State: Gestational Diabetes
A Systemic Prime–Intrarectal Pull Strategy Raises Rectum-Resident CD8+ T Cells for Effective Protection in a Murine Model of LM-OVA Infection
Frontiers in Immunology (Frontiers Media S.A.) China, 24 September 2020
Immunology
Key words: Mucosal Immune Response, Rectum TRM, Prime–Pull Vaccination Strategy, HIV, Listeria Monocytogenes [more]
Organism: Mouse
Tissue: Lung
Discoidin Domain Receptors 1 Inhibition Alleviates Osteoarthritis via Enhancing Autophagy
International Journal of Molecular Sciences (MDPI) Taiwan, 23 September 2020
Rheumatology
Key words: Discoidin Domain Receptors 1 (Ddr1), Osteoarthritis (OA), Autophagy, Apoptosis, Terminal Differentiation [more]
Organism: Mouse
Tissue: Bone
Pathological State: Osteoarthritis
Mechanical stress regulates autophagic flux to affect apoptosis after spinal cord injury
Journal of Cellular and Molecular Medicine (Wiley) China, 17 September 2020
Neuroscience
Key words: Apoptosis, Autophagic Flux, Decompression, Mechanical Stress, mTOR, Spinal Cord Injury [more]
Organism: Rabbit
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Two common polymorphic variants of OATP4A1 as potential risk factors for colorectal cancer
Oncology Letters (Spandidos Publications) Austria, Hungary, 17 September 2020
Oncology
Organism: Human
Tissue: Colon
Pathological State: Cancer
Placental Alkaline Phosphatase Promotes Zika Virus Replication by Stabilizing Viral Proteins through BIP
mBio (American Society for Microbiolgy) China, 15 September 2020
Virology
Key words: BIP, Placental Alkaline Phosphatase, Zika Virus, Placental Trophoblast Cells [more]
Organism: Human
Cell Line: U-251 MG, JEG-3, and HK2 cells
IL-20 antagonist suppresses PD-L1 expression and prolongs survival in pancreatic cancer models
Nature Communications (Nature) Taiwan, 14 September 2020
Oncology
Key words: Interleukins, Pancreatic Cancer [more]
Organism: Human
Tissue: Pancreas
Pathological State: Cancer
In vitro function and in situ localization of Multidrug Resistance-associated Protein (MRP) 1 (ABCC1) suggest a protective role against methyl mercury-induced oxidative stress in the human placenta
Archives of Toxicology (Springer) Austria, Czech Republic, 11 September 2020
Toxicology
Key words: Multidrug Resistance-Associated Protein 1, Methyl Mercury, HTR-8/Svneo, MDCKII, Oxidative Stress, Human Placenta [more]
Organism: Human
Tissue: Placenta
The Metalloproteinase ADAMTS5 Is Expressed by Interstitial Inflammatory Cells in IgA Nephropathy and Is Proteolytically Active on the Kidney Matrix
The Journal of Immunology (American Association of Immnologists) UK, 11 September 2020
Immunology
Organism: Human
Tissue: Kidney
Iminostilbene, a novel small-molecule modulator of PKM2, suppresses macrophage inflammation in myocardial ischemia-reperfusion injury
Journal of Advanced Research (Elsevier) China, 09 September 2020
Cardiology
Key words: Myocardial Ischemia-Reperfusion, Macrophage, Iminostilbene, Pyruvate Kinase M2 [more]
Organism: Rat
Tissue: Heart
Pathological State: Myocardial Ischemia
Progranulin Administration Attenuates β-Amyloid Deposition in the Hippocampus of 5xFAD Mice Through Modulating BACE1 Expression and Microglial Phagocytosis
Frontiers in Cellular Neuroscience (Frontiers Media S.A.) China, 03 September 2020
Neuroscience
Key words: Alzheimer’s Disease, Progranulin, Aβ, BACE1, Microglia [more]
Organism: Mouse
Tissue: Brain
Pathological State: Alzheimer's Disease
Integrin VLA-4 as a PET imaging biomarker of hyper-adhesion in transgenic sickle mice
Blood Advances (ASH Publications) USA, 03 September 2020
Cardiology
Key words: Adhesions, Biological Markers, Diagnostic Imaging, Integrins, Mice, Monoclonal Antibodies, Positron-Emission Tomography, Selectins, Flow Cytometry, Femur [more]
Organism: Mouse
Tissue: Bone, Spleen
Assessment of a long-term in vitro model to characterize the mechanical behavior and macrophage-mediated degradation of a novel, degradable, electrospun poly-urethane vascular graft
Journal of the Mechanical Behavior of Biomedical Materials (Elsevier) Austria, 03 September 2020
Tissue Engineering
Key words: Biodegradation, Mechanical Stability, Macrophages, Thermoplastic Polyurethane, Cell Culture, Rat Model [more]
Organism: Rat
Assessment of a long-term in vitro model to characterize the mechanical behavior and macrophage-mediated degradation of a novel, degradable, electrospun poly-urethane vascular graft
Journal of the Mechanical Behavior of Biomedical Materials (Elsevier) Austria, 03 September 2020
Biological Materials
Key words: Biodegradation, Mechanical Stability, Macrophages, Thermoplastic Polyurethane, Cell Culture, Rat Model
Murine induced pluripotent stem cell‐derived neuroimmune cell culture models emphasize opposite immune‐effector functions of interleukin 13‐primed microglia and macrophages in terms of neuroimmune toxicity
GLIA (Wiley) Belgium, Germany, Spain, The Netherlands, 31 August 2020
Neuroscience
Key words: Bioluminescence Imaging, Interleukin 13, iPSC, Macrophages, Microglia, Neurotoxicity, Transcriptome [more]
Organism: Human
Cell Line: iPSC‐macrophages
The Secretome of Stressed Peripheral Blood Mononuclear Cells Increases Tissue Survival in a Rodent Epigastric Flap Model
Bioengineering & Translational Medicine (Wiley) Austria, 30 August 2020
Tissue Engineering
Key words: Secretome, Angiogenesis, Flap Surgery, Necrosis Reconstructive Surgery, Tissue Regeneration [more]
Organism: Rat
Tissue: Skin
Alum triggers infiltration of human neutrophils ex vivo and causes lysosomal destabilization and mitochondrial membrane potential‐dependent NET‐formation
The FASEB Journal (Wiley) Austria, 29 August 2020
Cardiology
Key words: Aluminium Hydroxide, Vaccine, Adjuvant, Innate Response, Neutrophils, NET [more]
Organism: Human
Tissue: Skin
Radix Polygalae extract exerts antidepressant effects in behavioral despair mice and chronic restraint stress-induced rats probably by promoting autophagy and inhibiting neuroinflammation
Journal of Ethnopharmacology (Elsevier) China, 28 August 2020
Neuroscience
Key words: Depression, Radix Polygalae, Chronic Restraint Stress, Autophagy, Neuroinflammation [more]
Organism: Mouse
Tissue: Brain
Topography-Mediated Myotube and Endothelial Alignment, Differentiation, and Extracellular Matrix Organization for Skeletal Muscle Engineering
Polymers (MDPI) The Netherlands, 28 August 2020
Tissue Engineering
Key words: Myoblasts, Topography, Vascularization, Endothelial Cells, Skeletal Muscle, Extracellular Matrix [more]
Organism: Human
Tissue: Muscle
Effects of pharmacological calcimimetics on colorectal cancer cells over-expressing the human calcium-sensing receptor
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (Elsevier) Austria, 27 August 2020
Oncology
Key words: Calcium-Sensing Receptor, Calcimimetic, Colorectal Cancer, Inflammation, Intestine [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
The Effects of Skin Lesion Segmentation on the Performance of Dermatoscopic Image Classification
Computer Methods and Programs in Biomedicine (Elsevier) Austria, 26 August 2020
Medical Image Analysis
Key words: Skin Cancer, Dermatoscopy, Medical Image Analysis, Deep Learning, Effect of Segmentation on Classification
Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma
Genome Biology (BMC) South Korea, Italy, China, USA, 26 August 2020
Oncology
Organism: Human
Tissue: Brain
Pathological State: Cancer
Hindbrain Double-Negative Feedback Mediates Palatability-Guided Food and Water Consumption
CELL (Cell Press) USA, 24 August 2020
Neuroscience
Key words: Hunger, Thirst, Palatability, Locus Coeruleus, Locus Ceruleus, periLC, Ingestive Behavior, Appetite, In Vivo Calcium Imaging, GRIN Lens [more]
Organism: Mouse
Interruption of vascular endothelial growth factor receptor 2 signaling induces a proliferative pulmonary vasculopathy and pulmonary hypertension
Basic Research in Cardiology (Springer) Austria, Germany, 23 August 2020
Pulmonology
Key words: Pulmonary Hypertension, VEGFR-2, FLK, Kdr, Murine Model [more]
Organism: Mouse
Tissue: Lung
Loss of Bcl-6-expressing T follicular helper cells and germinal centers in COVID-19
CELL (Cell Press) USA, Canada, 19 August 2020
SARS-CoV-2
Key words: SARS-CoV-2, COVID-19, T Follicular Helper Cells, Germinal Centers, Double-Negative B Cells, Extra-Follicular B Cells, Plasmablasts, Humoral Immunity, TNF-α, Cytokine Dysregulation [more]
Organism: Human
Tissue: Lymphoid Tissue, Spleen
Pathological State: Covid-19
Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer
Nature Communications (Nature) USA, 19 August 2020
Oncology
Key words: Epigenomics, Prostate Cancer, Targeted Therapies [more]
Organism: Human
Tissue: Prostate
Pathological State: Cancer
Short-course radiotherapy promotes pro-inflammatory macrophages via extracellular vesicles in human rectal cancer
Journal for ImmunoTherapy of Cancer (BMJ Journals) Austria, 18 August 2020
Oncology
Key words: Macrophages, Radiotherapy, Tumor Microenvironment [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Epithelial cell–specific loss of function of Miz1 causes a spontaneous COPD-like phenotype and up-regulates Ace2 expression in mice
Science Advances (AAAS) USA, China, 14 August 2020
Immunology
Organism: Human
Tissue: Lung
Pathological State: Chronic Obstructive Pulmonary Disease
Prenatal smoke exposure dysregulates lung epithelial cell differentiation in mouse offspring-Role for AREG-induced EGFR signaling.
American Journal of Physiology (APS Journals) The Netherlands, China, 12 August 2020
Pulmonology
Key words: Prenatal Smoke Exposure, Epithelial Cell Differentiation, Amphiregulin, Lung Organoids [more]
Organism: Mouse
Tissue: Lung
Dysregulated Kras/YY1/ZNF322A/Shh transcriptional axis enhances neo-angiogenesis to promote lung cancer progression
Theranostics (Ivyspring International Publisher) Taiwan, 08 August 2020
Oncology
Key words: Lung Cancer, Kras, Shh, Transcription, Angiogenesis [more]
Organism: Human
Tissue: Lung
Pathological State: Cancer
The effects of CYP24A1 on clinicopathological features and the prognosis of pancreatic ductal adenocarcinoma
Translational Cancer Research (AME Publishing Company) China, 08 August 2020
Oncology
Key words: CYP24A1, Pancreatic Cancer, Prognosis [more]
Organism: Human
Tissue: Pancreas
Pathological State: Cancer
Human FBXL8 Is a Novel E3 Ligase Which Promotes BRCA Metastasis by Stimulating Pro-Tumorigenic Cytokines and Inhibiting Tumor Suppressors
Cancers (MDPI) Taiwan, Singapore, 07 August 2020
Oncology
Key words: FBXL8 SCF E3 Ubiquitin Ligase, CCND2, IRF5, Breast Cancer (BRCA) And Metastasis, Pro-Tumorigenic Microenvironment [more]
Organism: Human
Cell Line: MCF7 and MDA-MB231 cells
Pyramidal shaped ceria nano-biointerfaces for studying the early bone cell response
Applied Surface Science (Elsevier) Romania, 06 August 2020
Biological Materials
Key words: Pyramidal Shaped Ceria Nano-Biointerfaces, PLD, Cells Response [more]
Organism: Human
Cell Line: Human osteosarcoma cells (SaOs-2)
Sodium Cholate Bile Acid-Stabilized Ferumoxytol-Doxorubicin-Lipiodol Emulsion for Transcatheter Arterial Chemoembolization of Hepatocellular Carcinoma
Journal of Vascular and Interventional Radiology (Elsevier) USA, 06 August 2020
Oncology
Organism: Rat
Tissue: Liver
Pathological State: Cancer
Light‐emitting diode irradiation induces AKT/mTOR‐mediated apoptosis in human pancreatic cancer cells and xenograft mouse model
Journal of Cellular Physiology (Wiley Online Library) South Korea, 04 August 2020
Oncology
Key words: AKT/mTOR Pathway, Apoptosis, LED Irradiation, Pancreatic Cancer, Tumor Growth [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor
Nature Communications (Nature) USA, China, 04 August 2020
Virology
Key words: Chemical Tools, Proteomics, Virus–Host Interactions [more]
Organism: Human
Cell Line: HEK293T cells
Preclinical investigation of ovatodiolide as a potential inhibitor of colon cancer stem cells via downregulating sphere-derived exosomal β-catenin/STAT3/miR-1246 cargoes
American Journal of Cancer Research (e-Century Publishing Corporation) Taiwan, China, 01 August 2020
Oncology
Key words: Colon Cancer Stem Cells, Tumor Microenvironment, 5-FU Resistance, Tumorsphere Derived Exosomes, Β-Catenin/STAT3/MiR-1246 Signaling, Ovatodiolide [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Endocrine-disrupting chemicals rapidly affect intercellular signaling in Leydig cells
Toxicology and Applied Pharmacology (Elsevier) Czech Republic, Slovakia, 31 July 2020
Endocrinology
Key words: Connexins, Endocrine-Disrupting Chemicals, Gap Junctional Intercellular Communication, Leydig Cells, Reproductive Toxicants, Steroidogenesis [more]
Organism: Mouse
Cell Line: Leydig TM3 cells
A Curcumin Analog Exhibits Multiple Biologic Effects on the Pathogenesis of Alzheimer's Disease and Improves Behavior, Inflammation, and β-Amyloid Accumulation in a Mouse Model
International Journal of Molecular Sciences (MDPI) Taiwan, 30 July 2020
Neuroscience
Key words: Alzheimer’s Disease Therapy, Curcumin Analog, TML-6, Aging, Bioavailability [more]
Organism: Mouse
Tissue: Brain
Pathological State: Alzheimer's Disease
Expression of Melatonin Receptor 1 in Rat Mesenteric Artery and Perivascular Adipose Tissue and Vasoactive Action of Melatonin
Cellular and Molecular Neurobiology (Springer) Slovakia, Austria, 30 July 2020
Cardiology
Key words: Rat Melatonin Receptor MT1, Melatonin, Mesenteric Artery (MA), Perivascular Fat Tissue (PVAT), Neurogenic Contraction [more]
Organism: Rat
Tissue: Eye, Brain
Hydroxysafflor Yellow A Protects Against Myocardial Ischemia/Reperfusion Injury via Suppressing NLRP3 Inflammasome and Activating Autophagy
Frontiers in Pharmacology (Frontiers Media S.A.) China, 30 July 2020
Cardiology
Key words: Myocardial Ischemia Reperfusion Injury, Hydroxysafflor Yellow A, NLRP3, Autophagy, AMPK [more]
Organism: Rat
Tissue: Heart
Pathological State: Myocardial Ischemia
NHF-derived carbon dots: prevalidation approach in breast cancer treatment
Scientific Reports (Nature) Romania, 29 July 2020
Oncology
Key words: Cancer, Drug Development, Medical Research, Oncology, Preclinical Research, Translational Research [more]
Organism: Human
Cell Line: HUVECs and PASMCs
BMI1-Mediated Pemetrexed Resistance in Non-Small Cell Lung Cancer Cells Is Associated with Increased SP1 Activation and Cancer Stemness
Cancers (MDPI) Taiwan, 27 July 2020
Oncology
Key words: BMI1, SP1, Pemetrexed Resistance, Non Small Cell Lung Cancer, Cancer Stem Cells, Epithelial–Mesenchymal Transition [more]
Organism: Mouse
Tissue: Lung
Pathological State: Cancer
A general method to optimize and functionalize red-shifted rhodamine dyes
Nature Methods (Nature) USA, 27 July 2020
Biological Methods
Key words: Chemical Biology, Chemical Tools, Fluorescence Imaging, Imaging [more]
Organism: Mouse
Tissue: Brain
Ready to go 3D? A semi-automated protocol for microwell spheroid arrays to increase scalability and throughput of 3D cell culture testing
Toxicology Mechanisms and Methods (Taylor & Francis) Czech Republic, USA, 26 July 2020
Biological Methods
Organism: Human
Cell Line: HL1-hT1 cells and HepG2 cells
Imaging of metabolic activity adaptations to UV stress, drugs and differentiation at cellular resolution in skin and skin equivalents–Implications for oxidative UV damage
Redox Biology (Elsevier) Austria, Italy, USA, 19 July 2020
Dermatology
Organism: Human
Tissue: Skin
Enterocyte-Based Bioassay via Quantitative Combination of Proinflammatory Sentinels Specific to 8-keto-trichothecenes
Frontiers in Immunology (Frontiers Media S.A.) South Korea, 16 July 2020
Immunology
Key words: 8-Keto-Trichothecene, Ribotoxic Stress, Inflammation, Epithelium, Reporter Biomonitoring [more]
Organism: Mouse
Tissue: Small Intestine
Neutrophil Extracellular Trap Degradation by Differently Polarized Macrophage Subsets
Arteriosclerosis, Thrombosis and Vascular Biology (American Heart Association) Austria, 16 July 2020
Cardiology
Key words: Aortic Aneurysm, Extracellular Traps, Humans, Macrophages, Thrombosis [more]
Organism: Mouse
Cell Line: Blood
Pre-and post-irradiation mild hyperthermia enabled by NIR-II for sensitizing radiotherapy
Biomaterials (Elsevier) China, 14 July 2020
Biological Materials
Key words: Au Nanobipyramids, Second Near-Infrared Window, Mild Hyperthermia, Radiotherapy [more]
Organism: Mouse
Tissue: Allograft Tumor
Pathological State: Cancer
Antidiabetic activity in vitro and in vivo of BDB, protein tyrosine phosphatase 1B selective inhibitor from Rhodonela conferviodes
British Journal of Pharmacology (Wiley) China, 14 July 2020
Pharmacology
Key words: Bromophenol, PTP1B Inhibitor, Selectivity, Cell Permeability, Oral Bioavailability [more]
Organism: Mouse
Tissue: Pancreas
Pathological State: Diabetes
Multivalent Clustering of Adhesion Ligands in Nanofiber-Nanoparticle Composites
Acta Biomaterialia (SSRN) France, USA, 13 July 2020
Biological Materials
Key words: Peptide Amphiphile, Silica Particles, Nanobiocomposites, Hybrid Biomaterials, Clustering [more]
Organism: Mouse
Cell Line: NIH 3T3 fibroblasts
Lycopene Inhibit IMQ-Induced Psoriasis-Like Inflammation by Inhibiting ICAM-1 Production in Mice
Polymers (MDPI) Taiwan, 09 July 2020
Dermatology
Key words: Lycopene, Psoriasis [more]
Organism: Mouse
Tissue: Skin
Pathological State: Psoriasis
Using Cytometry for Investigation of Purinergic Signaling in Tumor‐Associated Macrophages
Cytometry Part A (Wiley) Brazil, 07 July 2020
Oncology
Key words: Macrophage, TAM, Cancer Stem Cells, Purines, ATP, Purinergic System, EMT, Image Cytometry [more]
Organism: Human
Pathological State: Cancer
Cell Line: Macrophages
Multimodal single‐cell analysis reveals distinct radioresistant stem‐like and progenitor cell populations in murine glioma
GLIA (Wiley) USA, Italy, Sweden, 04 July 2020
Neuroscience
Key words: Glioma, Glioma Stem Cells, Myeloid Cells, Radiation Response, Radioresistance, Single‐Cell RNA Sequencing, SP Analysis [more]
Organism: Mouse
Tissue: Brain
Pathological State: Cancer
Catching Common Cold Virus with a Net: Pyridostatin Forms Filaments in Tris Buffer That Trap Viruses—A Novel Antiviral Strategy?
Viruses (MDPI) Austria, Sweden, 04 July 2020
Virology
Key words: Enterovirus, Rhinovirus, Pyridostatin, Filament, Extracellular Traps [more]
Organism: Human
Cell Line: HeLa Cells
Fewer tumour-specific PD-1+ CD8+ TILs in high-risk “Infiltrating” HPV− HNSCC
British Journal of Cancer (Nature) China, 03 July 2020
Oncology
Key words: Head and Neck Cancer, Tumour Immunology [more]
Organism: Human
Tissue: Head and Neck
Pathological State: Cancer
Slug Is A Surrogate Marker of Epithelial to Mesenchymal Transition (EMT) in Head and Neck Cancer
Journal of Clinical Medicine (MDPI) Austria, 30 June 2020
Oncology
Key words: Image Cytometry, p16, p53, Cancer Stem Cells, E-Cadherin, β -Catenin, EMT, Head and Neck Cancer [more]
Organism: Human
Tissue: Head and Neck
Pathological State: Cancer
Functional characterization of the basal amygdala-dorsal BNST pathway during contextual fear conditioning
eNeuro (Society for Neuroscience) USA, 29 June 2020
Neuroscience
Key words: Contextual Fear, Fear Memorybasal Amygdala, Bed Nucleus of The Stria Terminalis, Neural Circuits, Encoding, Fear Engram [more]
Organism: Mouse
Tissue: Brain
Tissues derived from reprogrammed Wharton's jelly stem cells of the umbilical cord as a platform to study gestational diabetes mellitus
Stem Cell Research (Elsevier) Singapore, 26 June 2020
Stem Cell Research
Key words: Gestational Diabetes Mellitus, Induced Pluripotent Stem Cells, Reprogramming, Wharton’s Jelly Stem Cells, Pancreatic Cells [more]
Organism: Human
Pathological State: Gestational Diabetes
Cell Line: iPSCs
Comparison between paramagnetic and CD71 magnetic activated cell sorting of fetal nucleated red blood cells from the maternal blood
Journal of Clinical Laboratory Analysis (Wiley) Romania, 25 June 2020
Biological Methods
Key words: CD71, Fluorescent in Situ Hybridization, Magnetic‐Activated Cell Sorting, Nucleated Red Blood Cells, Prenatal Diagnosis [more]
Organism: Human
Cell Line: Blood
BMI1-KLF4 axis deficiency improves responses to neoadjuvant concurrent chemoradiotherapy in patients with rectal cancer
Radiotherapy and Oncology (Elsevier) Taiwan, 24 June 2020
Radiotherapy, Oncology
Key words: BMI1, CCRT, Rectal Cancers, Radioresistance [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
The chemokine lymphotactin and its recombinant variants in oral cancer cell regulation
Oral Diseases (Wiley) UK, 19 June 2020
Oncology
Key words: Cancer‐Associated Fibroblast, Lymphotactin, Oral Squamous Cell Carcinoma, Tumour Microenvironment, XCR1 [more]
Organism: Human
Tissue: Lymphoid Tissue
Pathological State: Cancer
p16 in highly malignant esophageal carcinomas: the correlation with clinicopathological factors and human papillomavirus infection
Virchows Archiv (Springer) Japan, Australia, Germany, 16 June 2020
Oncology
Key words: Esophagus, Small-Cell Carcinoma, Poorly Differentiated Squamous Cell Carcinoma, Basaloid Squamous Cell Carcinoma, P16, Human Papillomavirus [more]
Organism: Human
Tissue: Esophagus
Pathological State: Cancer
Reciprocal Regulation Between Indoleamine 2, 3-Dioxigenase 1 and Notch1 Involved in Radiation Response of Cervical Cancer Stem Cells
Cancers (MDPI) Taiwan, 12 June 2020
Oncology, Stem Cell Research
Key words: IDO1, Notch1, Radiation, Cervical Cancer, Cancer Stem Cells [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Tumor Microenvironment Targeting Nano–Bio Emulsion for Synergistic Combinational X‐Ray PDT with Oncolytic Bacteria Therapy
Advanced Healthcare Materials (Wiley) South Korea, USA, 11 June 2020
Oncology, Nanomedicine
Key words: Bacteriolytic Therapy, Nano–Bio Emulsions, Scintillating Nanoparticles, Tumor Microenvironments, X‐Ray Photodynamic Therapy (PDT) [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Regulatory T cells promote adipocyte beiging in subcutaneous adipose tissue
The FASEB Journal (Wiley) USA, China, 08 June 2020
Immunology
Key words: Epididymal White Adipose Tissue, Gonadal White Adipose Tissue, Macrophage Polarization, Regulatory T Cell, Subcutaneous Adipose Tissue, Uncoupling Protein‐1
Yttrium-90 Radioembolization and Tumor Hypoxia: Gas-challenge BOLD Imaging in the VX2 Rabbit Model of Hepatocellular Carcinoma
Academic Radiology (Elsevier) USA, 07 June 2020
Radiotherapy, Oncology
Key words: Oxygenation, Hepatic Radioembolization, Magnetic Resonance Imaging, Yttrium-90 [more]
Organism: Rabbit
Tissue: Kidney
Pathological State: Cancer
A prominent environmental endocrine disruptor, 4-nonylphenol, promotes endometriosis development via plasmacytoid dendritic cells
Molecular Human Reproduction (Oxford Academic) Taiwan, 04 June 2020
Reproductive Medicine
Key words: CD36, Endometriosis, Environmental Endocrine Disruptor, Estrous Cycle, IL-10, 4-Nonylphenol, Plasmacytoid Dendritic Cell [more]
Organism: Mouse
Tissue: Uterus
Pathological State: Endometriosis
A missense mutation of ErbB2 produces a novel mouse model of stillbirth associated with a cardiac abnormality but lacking abnormalities of placental structure
PLoS One (PLOS) UK, 03 June 2020
Reproductive Medicine
Key words: Mouse Models, Stillbirths, Embryos, Placenta, Fetal Death, Myocardium, Heart, Giant Cells [more]
Organism: Mouse
Tissue: Placenta