Customer Publications (A total of 2600 papers published)
Freshwater cyanotoxin cylindrospermopsin has detrimental stage-specific effects on hepatic differentiation from human embryonic stem cells
Toxicological Sciences (Oxford University Press) Czech Republic, 30 November 2018
Stem Cell Research
Key words: cylindrospermopsin, hepatic differentiation, human embryonic stem cells, liver, cyanotoxin [more]
Organism: Human
Cell Line: Human embryonic stem cell (hESCs)
Pterostilbene Attenuates Hexavalent Chromium-Induced Allergic Contact Dermatitis by Preventing Cell Apoptosis and Inhibiting IL-1β-Related NLRP3 Inflammasome Activation
Journal of Clinical Medicine (MDPI) Taiwan, 27 November 2018
Allergy Research
Key words: Hexavalent chromium, pterostilbene, endoplasmic reticulum stress, inflammatory cytokines, NLRP3 inflammasome, allergic contact dermatitis [more]
Organism: Mouse
Tissue: Skin
Pathological State: Dermatitis
ONECUT2 Is a Targetable Master Regulator of Lethal Prostate Cancer That Suppresses the Androgen Axis
Nature Medicine (Nature) USA, Taiwan, 26 November 2018
Oncology
Immune Cell and Cell Cluster Phenotyping, Quantitation, and Visualization Using In Silico Multiplexed Images and Tissue Cytometry
Cytometry Part A (Wiley) USA, 23 November 2018
Cytometry
Key words: immune cells, cell clusters, quantitative imaging, multiplexed histology, tissue cytometry, TissueFAXS in silico analysis, FFPE [more]
Organism: Mouse
Tissue: Spleen
Pathological State: Cancer
PD-L1 expression and the prognostic significance in gastric cancer: a retrospective comparison of three PD-L1 antibody clones (SP142, 28–8 and E1L3N)
Diagnostic Pathology (Springer) China, 21 November 2018
Oncology
Key words: Programmed cell death ligand 1, Immunohistochemistry, H-score, Multiplexed immunofluorescence [more]
Organism: Human
Tissue: Stomach
Pathological State: Cancer
MicroRNA-451a overexpression induces accelerated neuronal differentiation of Ntera2/D1 cells and ablation affects neurogenesis in microRNA-451a-/- mice
PLoS One (PLOS) Austria, 21 November 2018
Neuroscience
Key words: Neuronal differentiation, Neurites, Cell differentiation, Neurospheres, MicroRNAs, Neural networks, Fluorescence microscopy, Nestin [more]
Organism: Mouse
Tissue: Brain
Oxidative muscles have better mitochondrial homeostasis than glycolytic muscles throughout life and maintain mitochondrial function during aging
Aging (Impact Journals) USA, 18 November 2018
Physiology
Key words: Aging, glycolytic, mitochondria, oxidative, sarcopenia, skeletal muscle [more]
Organism: Mouse
Tissue: Muscle
Generation of human iPSCs from human prostate cancer-associated fibroblasts IBPi002-A
Stem Cell Research (Elsevier) Czech Republic, 16 November 2018
Stem Cell Research
Key words: induced stem cells, iPSCs, prostate fibroblasts, IBPi00-2 [more]
Organism: Human
Cell Line: Induced pluripotent cells (iPSCs)
Effect of dentin matrix components on the mineralization of human mesenchymal stromal cells
Tissue Engineering Part A (Mary Ann Liebert Inc.) The Netherlands, UK, 16 November 2018
Regenerative Medicine
Key words: dental pulp, dentin matrix, mesenchymal stromal cells, mineralization, tissue engineering, umbilical cord [more]
Organism: Human
Cell Line: Dental pulp stem cells (DPSCs), Adipose tissue derived stem cells (ASCs)
Hepatocellular carcinoma-targeted nanoparticles for cancer therapy
International Journal of Oncology (Spandidos Publications) Taiwan, 16 November 2018
Oncology
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Semi-Automated and Manual Methods for Counting Cells Expressing P75 Receptor in Endometriotic Lesions
International Conference on Science and Technology-Computer (ICST) () Indonesia, Austria, 12 November 2018
Cytometry
Key words: Observers, Immune system, Software, Lesions, Manuals, Biomedical imaging, Tools
Novel Protective Effects of Cistanche Tubulosa Extract Against Low-Luminance Blue Light-Induced Degenerative Retinopathy
Cellular Physiology and Biochemistry (Karger) Taiwan, 07 November 2018
Ophthalmology
Key words: Cistanche tubulosa extract • Blue light • Apoptosis • Retinal pigment epithelial cells [more]
Organism: Human
Cell Line: Retinal pigment epithelium cells (RPEs)
Increased frequency of systemic pro-inflammatory Vδ1+ γδ T cells in HIV elite controllers correlates with gut viral load
Scientific Reports (Nature) USA, 07 November 2018
Immunology, Virology
Key words: Chronic inflammation, Gammadelta T cells, HIV infections, Infection, Mucosal immunology [more]
Organism: Human
Tissue: Small Intestine
Pathological State: HIV Infection
Loss of BAP1 expression is associated with genetic mutation and can predict outcomes in gallbladder cancer
PLoS One (PLOS) Japan, USA, 05 November 2018
Oncology
Key words: DNA methylation, Small interfering RNAs, Polymerase chain reaction, Methylation, Mutation detection, Prognosis, DNA sequence analysis, Nonsense mutation [more]
Organism: Human
Pathological State: Cancer
Genetic ablation of NFAT5/TonEBP in smooth muscle cells impairs flow- and pressure-induced arterial remodeling in mice
The FASEB Journal (FASEB) Germany, 01 November 2018
Regenerative Medicine
Key words: hypertension, wall stress, transcriptome [more]
Organism: Mouse
Cell Line: Primary aterial smooth muscle cells, vascular smooth muscle cells (VSMCs )
Genetic ablation of NFAT5/TonEBP in smooth muscle cells impairs flow-and pressure-induced arterial remodeling in mice
The FASEB Journal (FASEB) Germany, 01 November 2018
Cardiology
Key words: hypertension, wall stress, transcriptome [more]
Organism: Mouse
Cell Line: Vascular Smooth Muscle Cells
Tissue and host species-specific transcriptional changes in models of experimental visceral leishmaniasis
Wellcome Open Research (Wellcome Open Research) UK, 29 October 2018
Parasitology
Key words: Leishmania, infection, host response, transcriptomics, immunopathology [more]
Organism: Mouse
Tissue: Spleen, Liver
Pathological State: Leishmaniasis
Azo-based small molecular hypoxia responsive theranostic for tumor-specific imaging and therapy
Journal of Controlled Release (Elsevier) China, India, South Korea, 28 October 2018
Oncology
Key words: molecular hypoxia, theranostic, tumor-specific imaging, [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
PI3K: A master regulator of brain metastasis‐promoting macrophages/microglia
GLIA (Wiley) Germany, 25 October 2018
Oncology
Key words: Astrocytes, BKM120, brain metastasis, macrophages, microglia, PI3K, RPPA [more]
Organism: Mouse
Pathological State: Cancer
Cell Line: Monocyte‐derived macrophages (MDMs)
Alteration of mesenchymal stem cells polarity by laminar shear stimulation promoting β-catenin nuclear localization
Biomaterials (Elsevier) Taiwan, 23 October 2018
Stem Cell Research
Key words: β-catenin, Cardiovascular, Laminar shear, Mesenchymal stem cells, Wnt [more]
Organism: Human
Cell Line: Human mesenchymal stem cells (hMSCs)
Gene expression profiling in a mouse model of Dravet syndrom
Experimental Neurology (Elsevier) USA, 19 October 2018
Neuroscience
Key words: Epilepsy, Epileptic encephalopathy, Gene expression, RNA-seq, Seizure, Voltage-gated sodium channel [more]
Organism: Mouse
Tissue: Brain
Pathological State: Dravet Syndrome
Kinin-B2 Receptor Activity in Skeletal Muscle Regeneration and Myoblast Differentiation
Stem Cell Reviews and Reports (Springer) USA, Brazil, 18 October 2018
Stem Cell Research
Key words: Mouse myoblast differentiation, Muscle repair, Kinin-B2 receptor, HOE-140 [more]
Organism: Mouse
Cell Line: Myoblast cell line - C2C12 Cells
Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting
CELL (Cell Press) Israel, Austria, Sweden, 11 October 2018
Cell Biology
Key words: immune systemsingle-cell RNA sequencinglungbasophilsalveolar macrophagescellular interactiondevelopmentsignaling [more]
Organism: Mouse
Tissue: Lung
Early Immunologic Response of Irreversible Electroporation versus Cryoablation in a Rodent Model of Pancreatic Cancer
Journal of Vascular and Interventional Radiology (Elsevier) USA, 11 October 2018
Immunology
Key words: irreversible electroporation, Cryoablation, Pancreatic Cancer [more]
Organism: Mouse
Pathological State: Cancer
Cell Line: PANC-2 (Pancreatic cancer cell line)
Transforming growth factor beta 1 mediates the low-frequency vertical vibration enhanced production of tenomodulin and type I collagen in rat Achilles tendon
PLoS One (PLOS) Taiwan, 11 October 2018
Cell Biology
Key words: Tendons, Collagens, Gene expression, Stiffness, Vibration, Mechanical properties, Enzyme-linked immunoassays, Polymerase chain reaction [more]
Organism: Rat
Accelerated Aging and Clearance of Host Anti-inflammatory Enzymes by Discrete Pathogens Fuels Sepsis
Cell Host and Microbe (Cell Press) USA, 10 October 2018
Immunology, Microbiology
Key words: glycosylation, sepsis, neuraminidase, Toll-like receptor 4, alkaline phosphatase, Ashwell-Morell receptor, lipopolysaccharide, inflammation [more]
Organism: Mouse
Tissue: Liver
Pathological State: Sepsis
Inhibition of AKT suppresses the initiation and progression of BRCA1-associated mammary tumors
International Journal of Biological Sciences (Ivyspring International Publisher) South Korea, China, 10 October 2018
Oncology
Key words: BRCA1, AKT, MK-2206, precision medicine [more]
Organism: Mouse
Tissue: Breast
Pathological State: Cancer
Extracellular domain of EpCAM enhances tumor progression through EGFR signaling in colon cancer cells
Cancer Letters (Elsevier) Taiwan, 01 October 2018
Oncology
Key words: Epithelial cell adhesion molecule, Regulated intramembrane proteolysis, β-catenin, HIF1α [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Age, but not short-term intensive swimming, affects chondrocyte turnover in zebrafish vertebral cartilage
The Journal of Life and Environmental Sciences (PeerJ) Taiwan, 01 October 2018
Osteology
Key words: Aging, Cartilage, Osteoarthritis, Tissue homeostasis, Chondrocyte [more]
Organism: Fish
Tissue: Spinal Cord
Gd-EOB-DTPA DCE-MRI biomarkers in a rabbit model of liver fibrosis
American Journal of Translational Research (e-Century Publishing Corporation) China, USA, 30 September 2018
Hepathology
Key words: Liver fibrosis, animal, magnetic resonance imaging, pathology [more]
Organism: Rabbit
Tissue: Liver
Pathological State: Liver Fibrosis, Liver Cirrhosis
Modified Ginseng Extract Induces Apoptosis in HepG2 Cancer Cells by Blocking the CXCL8-Mediated Akt/Nuclear Factor-κB Signaling Pathway
The American Journal of Chinese Medicine (World Scientific) South Korea, 27 September 2018
Oncology
Key words: Modified Regular Ginseng Extract, MRGX, C-X-C Motif Chemokine Ligand 8, Liver Cancer, Akt, Nuclear Factor-κB, Apoptosis [more]
Organism: Human
Pathological State: Cancer
Cell Line: HepG2 (Liver carcinoma cell line)
Development of Decellularized Cornea by Organic acid Treatment for Corneal Regeneration
Tissue Engineering Part A (Mary Ann Liebert Inc.) Taiwan, 22 September 2018
Regenerative Medicine
Key words: cornea, decellularized scaffold, extracellular matrix, xenograft, corneal transplantation. [more]
Organism: Rabbit
Tissue: Eye
ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific manner
PLoS One (PLOS) USA, 18 September 2018
Oncology
Key words: Telomeres, Cloning, Glioma cells, Glioma, DNA cloning, Immunoblotting, Vector cloning, Polymerase chain reaction [more]
Organism: Human
Pathological State: Cancer
Cell Line: Glioma cell lines (MOG-G-UVW, SF188, U-251 and UW479)
The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases
Science Signaling (American Association for the Advancement of Science) Czech Republic, Belgium, USA, Norway, 18 September 2018
Cell Biology
Key words: SHIP2, ERK activation, FGF receptors, Src kinases [more]
Organism: Rat, Human
Pathological State: Cancer
Cell Line: U2OS (Osteosarcoma cell line), RCS cells (Cultured rat chondrosarcoma cell line)
Activation of estrogen receptor alpha induces beiging of adipocytes
Molecular Metabolism (Elsevier) USA, 15 September 2018
Cell Biology
Key words: Beige adipocytes, Lipolysis, Estrogen receptor alpha (ERα), Obesity, Type II diabetes mellitus (T2DM) [more]
Organism: Mouse
Tissue: Adipose Tissue
Pathological State: Obesity, Diabetes
Cellular-scale probes enable stable chronic subsecond monitoring of dopamine neurochemicals in a rodent model
Communications Biology (Nature) USA,, 12 September 2018
Neuroscience
Key words: Diagnostic markers, Neurochemistry, Parkinson's disease, Sensors and probes [more]
Organism: Rat
Tissue: Brain
Synthetic α5β1 integrin ligand PHSRN is proangiogenic and neuroprotective in cerebral ischemic stroke
Biomaterials (Elsevier) Taiwan, 11 September 2018
Biological Materials
Key words: Stroke, Fibronectin, PHSRN, α5β1, Angiogensis, Neurogenesis, VEGF [more]
Organism: Rat
Tissue: Brain
Factor Xa inhibition by rivaroxaban regulates fibrogenesis in human atrialfibroblasts with modulation of nitric oxide synthesis and calciumhomeostasis
Journal of Molecular and Cellular Cardiology (Elsevier) Taiwan, 10 September 2018
Physiology
Key words: Fibroblasts, Fibrosis, Rivaroxaban, Protease-activated receptor, Atrial fibrillation, Stroke [more]
Organism: Rat
Tissue: Heart
Pathological State: Cardiac Fibrosis, Myocardial Ischemia
Phenethyl Isothiocyanate Inhibits In Vivo Growth of Xenograft Tumors of Human Glioblastoma Cells
Molecules (MDPI) Taiwan, 10 September 2018
Oncology
Key words: phenethyl isothiocyanate, apoptosis, xenograft, caspase, glioblastoma [more]
Organism: Mouse
Tissue: Liver, Xenograft Tumor
Pathological State: Cancer
Androgen receptor expression inversely correlates with immune cell infiltration in human epidermal growth factor receptor 2–positive breast cancer
European Journal of Cancer (Elsevier) The Netherlands, China, 09 September 2018
Oncology
Key words: Androgen receptor expression, HER2-positive metastatic breast cancer, Immune cell infiltration, Trastuzumab resistance [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
TLR7 agonist attenuates acetylcholine‐induced, Ca2+‐dependent ionic currents in swine tracheal submucosal gland cells
Experimental Physiology (Wiley) Japan, 08 September 2018
Physiology
Key words: CaCC, COPD, hypersecretion, R837, submucosal glands [more]
Organism: Pig, Human
Tissue: Lung, Spleen
Inhibitory control of prefrontal cortex by the claustrum
Neuron (Cell Press) USA, UK, Canada, 05 September 2018
Neuroscience
Key words: claustrum prefrontal NPY PV neocortex feed-forward inhibition microcircuit neurogliaform cell somatostatin interneuron VIP [more]
Organism: Mouse
Tissue: Brain
Oxidized Low-Density Lipoprotein-Deteriorated Psoriasis Is Associated with the Upregulation of Lox-1 Receptor and Il-23 Expression In Vivo and In Vitro
International Journal of Molecular Sciences (MDPI) Taiwan, 03 September 2018
Dermatology
Key words: oxLDL, LOX-1, psoriasis [more]
Organism: Mouse
Tissue: Skin
Pathological State: Psoriasis
Enhanced Sternal Healing via Platelet-Rich Plasma and Biodegradable Gelatin Hydrogel
Tissue Engineering Part A (Mary Ann Liebert Inc.) Japan, 01 September 2018
Regenerative Medicine
Organism: Rabbit
Tissue: Bone
Amentoflavone Inhibits Hepatocellular Carcinoma Progression Through Blockage of ERK/NF-ĸB Activation
in vivo: international journal of experimental and clinical pathophysiology and drug research (International Institute of Anticancer Research) Taiwan, 01 September 2018
Oncology
Key words: Amentoflavone, hepatocellular carcinoma, extracellular signal-regulated kinase, nuclear factor-kappaB, bioluminescence imaging. [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
The tree shrew cerebellum atlas: Systematic nomenclature, neurochemical characterization and afferent projections
Journal of Comparative Neurology (Wiley) China, 29 August 2018
Neuroscience
Key words: cerebellar nuclei, lobule fissure, inferior olive, Purkinje cell, calbindin, RRID: AB_476894 [more]
Organism: Tree Shrew
Tissue: Brain
Focused Ultrasound-Induced Blood-Brain Barrier Opening Enhances GSK-3 Inhibitor Delivery for Amyloid-Beta Plaque Reduction
Scientific Reports (Nature) Taiwan, 27 August 2018
Neuroscience
Key words: Alzheimer's disease, eBiomedical engineering, Blood–brain barrier, Drug delivery, Translational research, GSK-3, Amyloid-Beta Plaque [more]
Organism: Mouse
Tissue: Brain
Pathological State: Alzheimer's Disease
Role of the orexin 2 receptor in palatable-food consumption-associated cardiovascular reactivity in spontaneously hypertensive rats
Scientific Reports (Nature) Taiwan, 23 August 2018
Cardiology
Key words: Hypertension, Hypothalamus [more]
Organism: Rat
Tissue: Brain
NFAT5 isoform C controls biomechanical stress responses of vascular smooth muscle cells
Frontiers in Physiology (Frontiers Media S.A.) Germany, 23 August 2018
Cardiology
Key words: NFAT5, TonEBP, hypertension, transcriptional regulation, vascular smooth muscle cells, wall stress [more]
Organism: Human
Cell Line: Human arterial smooth muscle cells (HUASMCs)
Photoperiodic Flower Mimicking Metallic Nanoparticles for Image-Guided Medicine Applications
ACS Applied Materials & Interfaces (ACS Publications) USA, 22 August 2018
Radiotherapy
Key words: metallic nanoparticles, radiosensitizers, image-guided radiotherapy, radiation, cancer therapy [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Optimization of an Anti-NMDA Receptor Autoantibody Diagnostic Bioassay
Circulation (NCBI) Taiwan, Denmark, Sweden, 22 August 2018
Neuroscience
Key words: Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis, autoantibody (autoAb), autoimmune encephalitis, schizophrenia, diagnostic test, fluorescein isothiocyanate (FITC), Alexa Fluor 488, antigen (Ag) [more]
Organism: Human
Pathological State: Encephalitis
Lack of DNA damage response at low radiation doses in adult stem cells contributes to organ dysfunction
Clinical Cancer Research (AACR Publications) The Netherlands, 22 August 2018
Oncology
Key words: DNA Damage, Radiation, Stem Cells, Organ Dysfunction, Radiotherapy [more]
Organism: Mouse
Tissue: Thyroid, Salivary Gland
Striatal Microstimulation Induces Persistent and Repetitive Negative Decision-Making Predicted by Striatal Beta-Band Oscillation
Neuron (Cell Press) USA, 22 August 2018
Neuroscience
Key words: approach-avoidance conflict, basal ganglia, beta oscillation, caudate nucleus, cost-benefit decisions, emotion, macaque, motivation, primate, value judgment [more]
Organism: Pig, Human
Tissue: Brain
Modified Methacrylate Hydrogels Improve Tissue Repair after Spinal Cord Injury
International Journal of Molecular Sciences (MDPI) Czech Republic, 22 August 2018
Regenerative Medicine
Key words: spinal cord injury, hydrogel, connective tissue, neurofilaments, locomotor test, plantar test [more]
Organism: Rat
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Secreted products of oral bacteria and biofilms impede mineralization of apical papilla stem cells in TLR-, species-, and culture-dependent fashion
Scientific Reports (Nature) The Netherlands, 21 August 2018
Immunology, Microbiology
Key words: Mesenchymal stem cells, Oral diseases, biofilms [more]
Organism: Human
Cell Line: SCAP (Stem cells from apical papilla)
Cbl-b deficiency provides protection against UVB-induced skin damage by modulating inflammatory gene signature
Cell Death & Disease (Nature) Austria, 06 August 2018
Oncology
Key words: Cbl-b deficiency, UVB, skin damage, inflammation, gene signature [more]
Organism: Mouse, Human
Tissue: Skin
Expression and modulation of S100A4 protein by human mast cells
Cellular Immunology (Elsevier) Italy, 04 August 2018
Immunology
Key words: Immunofluorescence Tryptase Metalloproteinase Mast cells biology siRNA [more]
Organism: Human
Tissue: Skin
Pathological State: Bladder Cyst, Crohn's Disease, Cancer
Degeneration of white matter and gray matter revealed by diffusion tensor imaging and pathological mechanism after spinal cord injury in canine
CNS Neuroscience and Therapeutics (Wiley) China, 03 August 2018
Neuroscience
Key words: canine model, diffusion tensor imaging, gray matter, pathological degeneration, spinal cord injury, white matter [more]
Organism: Dog
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Crumpled Aluminum Hydroxide Nanostructures as a Microenvironment Dysregulation Agent for Cancer Treatment
Nano Letters (ACS Publications) Russia, Israel, Slovenia, 02 August 2018
Nanomedicine
Key words: aluminum hydroxide, cancer treatment, Crumpled nanosheets, ion balance, molecular dynamics simulation, tumor microenvironment [more]
Organism: Mouse
Tissue: Allograft Tumor
Pathological State: Cancer
Plk1 overexpression suppresses tumor development by inducing chromosomal instability
Nature Communications (Nature) Spain, Germany, UK, 01 August 2018
Oncology
Key words: Cancer, Cell biology [more]
Organism: Mouse
Tissue: Breast
Pathological State: Cancer
SCID/NOD mice model for 5-FU induced intestinal mucositis: Safety and effects of probiotics as therapy
Pediatrics and Neonatology (Elsevier) Taiwan, 26 July 2018
Gastroenterology
Key words: SCID, cytokines, fluorouracil, mucositis, probiotics [more]
Organism: Mouse
Tissue: Small Intestine
Pathological State: Diarrhea
Trehalose to cryopreserve human pluripotent stem cells
Stem Cell Research (Elsevier) Italy, 25 July 2018
Stem Cell Research
Key words: Cryopreservation, Trehalose, Pluripotent stem cells [more]
Organism: Human
Cell Line: hESCs, lt-NES, hiPSCs
Depletion of Sirt3 leads to the impairment of adipogenic differentiation and insulin resistance via interfering mitochondrial function of adipose-derived human mesenchymal stem cells
Free Radical Research (Taylor and Francis) Taiwan, 23 July 2018
Stem Cell Research
Key words: Adipogenesis, antioxidant defence, human mesenchymal stem cells, insulin resistance, mitochondrial bioenergetics, Sirt3 [more]
Organism: Human
Cell Line: adiposederived human mesenchymal stem cells
Succinate Accumulation Is Associated with a Shift of Mitochondrial Respiratory Control and HIF-1α Upregulation in PTEN Negative Prostate Cancer Cells
International Journal of Molecular Sciences (MDPI) Austria, 21 July 2018
Oncology
Key words: Na+-dicarboxylate transporter, acidic tumor microenvironment, mitochondria, oxidative phosphorylation, prostate cancer, succinate [more]
Organism: Human
Pathological State: Cancer
Cell Line: LNCaP, PC-3 (prostate cancer cell lines)
Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion
Autophagy (Taylor and Francis) The Netherlands, 20 July 2018
Cell Biology
Key words: Autophagy, Golgi, bafilomycin A1, degradative compartments, fusion, lysosomal degradation, lysosomal inhibitors [more]
Organism: Human
Pathological State: Cancer
Cell Line: U2OS (Osteosarcoma cell line), HeLa cells
Prognostic and predictive values of immune infiltrate in patients with head and neck squamous cell carcinoma
Human Pathology (Elsevier) China, 20 July 2018
Oncology
Key words: Head and Neck Squamous Cell Carcinoma, Immunoscore, Prognosis and Predictive, Tumor Infiltrating Lymphocytes [more]
Organism: Human
Tissue: Head and Neck
Pathological State: Cancer
Significant therapeutic effects of adult human multipotent neural cells on spinal cord injury
Stem Cell Research (Elsevier) South Korea, 19 July 2018
Stem Cell Research
Key words: Spinal cord injuries, Adult stem cells, Neural stem cells, Microvasculature, Chemokine1 [more]
Organism: Rat
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Trop-2 plasticity is controlled by epithelial-to-mesenchymal transition
Carcinogenesis (Oxford University Press) Czech Republic, 16 July 2018
Oncology
Key words: phenotype, cancer, carcinoma, epithelium, heterogeneity, antigens, cell lines, membrane glycoproteins, breast, neoplasms, prostate, transcription factor, prostate cancer, carcinogenesis, e-cadherin, tumor progression, epithelial to mesenchymal transition, molecular targeted therapy, tumor cells, malignant [more]
Organism: Human
Tissue: Prostate, Breast
Pathological State: Cancer
Enhancement of chondrogenesis of adipose-derived stem cells in HA-PNIPAAm-CL hydrogel for cartilage regeneration in rabbits
Scientific Reports (Nature) Taiwan, 12 July 2018
Regenerative Medicine
Key words: Biomaterials, Regeneration, hydrogel, cartilage [more]
Organism: Rabbit
Cell Line: rADSCs (rabbit adipose-derived stem cells )
Synergistic Cross‐Talk of Hedgehog and Interleukin‐6 Signaling Drives Growth of Basal Cell Carcinoma
International Journal of Cancer (Wiley) Austria, 10 July 2018
Oncology
Key words: GLI signaling, GLI transcription factors, STAT transcription factors, basal cell carcinoma, hedgehog, interleukin-6 signaling [more]
Organism: Mouse
Tissue: Allograft Tumor
Pathological State: Cancer
Expression of serine peptidase inhibitor Kunitz type 1 in differentiated thyroid cancer
Histochemistry and Cell Biology (Springer) Taiwan, 10 July 2018
Oncology
Key words: Serine protease inhibitor, Hepatocyte growth factor, Thyroid cancer Invasion [more]
Organism: Human
Tissue: Thyroid
Pathological State: Cancer
TERT Promoter Mutations in Solitary Fibrous Tumor
HistoPathology (Wiley) USA, 09 July 2018
Oncology
Key words: ATRX, DAXX, metastasis, outcome, prognosis, risk assessment, solitary fibrous tumour, telomerase reverse transcriptase [more]
Organism: Human
Pathological State: Cancer
Development of a Novel Orthogonal Double Gradient for High‐Throughput Screening of Mesenchymal Stem Cells–Materials Interaction
Advanced Materials Interfaces (Wiley) The Netherlands, 04 July 2018
Biological Materials
Key words: high‐throughput screening, orthogonal double gradient, stem cell, stiffness, wettability [more]
Organism: Human
Cell Line: Mesenchymal stem cells from human bone marrow (hBM-MSCs)
Benzyl isothiocyanate inhibits human brain glioblastoma multiforme GBM 8401 cell xenograft tumor in nude mice in vivo
Environmental Toxicology (Wiley) Taiwan, 04 July 2018
Oncology
Key words: benzyl isothiocyanate, human brain glioblastoma multiforme GBM 8401 cell, in vivo, nude mice, xenograft tumor [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Antrodia cinnamomea produces anti-angiogenic effects by inhibiting the VEGFR2 signaling pathway
Journal of Ethnopharmacology (Elsevier) Taiwan, 28 June 2018
Cell Biology
Key words: Antrodia cinnamomea, Anti-angiogenic activity, Endothelial cells, VEGFR2, STAT3 [more]
Organism: Mouse
Tissue: Lung
Pathological State: Cancer
Dynamics of tissue ingrowth in SIKVAV-modified highly superporous PHEMA scaffolds with oriented pores after bridging a spinal cord transection
Journal of Materials Science: Materials in Medicine (Springer) Czech Republic, 25 June 2018
Regenerative Medicine
Key words: tissue ingrowth, SIKVAV, superporous, PHEMA scaffolds, oriented pores, spinal cord injury, mesenchymal stem cells (MSCs) [more]
Organism: Rat
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Neuroplastic change of cytoskeleton in inferior colliculus after auditory deafferentation
Hearing Research (Elsevier) South Korea, 23 June 2018
Neuroscience
Key words: Auditory deafferentation, Deafness, SMI-32, Neurofilament heavy chain, Inferior colliculus [more]
Organism: Rat
Tissue: Brain
Pathological State: Deafness
Androgen excess in pancreatic β cells and neurons predisposes female mice to type 2 diabetes
The Journal of Clinical Investigation (American Society for Clinical Investigation) USA, 21 June 2018
Oncology
Key words: Beta cells, Diabetes, Endocrinology, Metabolism, Sex hormones [more]
Organism: Mouse
Tissue: Pancreas
Pathological State: Diabetes
Afatinib restrains K-RAS–driven lung tumorigenesis
Science Translational Medicine (American Association for the Advancement of Science) Austria, 20 June 2018
Oncology
Key words: Afatinib, K-RAS, lung cancer, pan-ERBB, tyrosine kinase inhibitors [more]
Organism: Mouse
Tissue: Lung
Pathological State: Cancer
Competition between TIAM1 and Membranes Balances Endophilin A3 Activity in Cancer Metastasis
Developmental Cell (Cell Press) USA, 18 June 2018
Oncology
Key words: BAR domain, PTEN, Rac1, TIAM1, cell migration, endocytosis, endophilin, membrane remodeling, metastasis [more]
Organism: Mouse
Tissue: Whole Organism
Pathological State: Cancer
Endothelial colony forming cells from human umbilical cord blood improved severe erectile dysfunction in obese type II diabetic rats
Life Science (Elsevier) Singapore, 18 June 2018
Reproductive Medicine
Key words: Severe erectile dysfunction, Human endothelial colony forming cells, Intracavernosal pressure, Zucker diabetic fatty rats [more]
Organism: Rat
Tissue: Penis
Pathological State: Erectile dysfunction
Quantitative measurement of breast carcinoma fibrosis for the prediction in the risk of bone metastasis
American Journal of Translational Research (e-Century Publishing Corporation) China, 15 June 2018
Oncology
Key words: Invasive breast carcinoma, bone metastasis, collagen deposition, early prediction [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles
EMBO Journal (EMBO press) The Netherlands, 15 June 2018
Oncology
Key words: Cre‐LoxP, extracellular vesicles, intratumoral heterogeneity, intravital microscopy, signaling networks [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Substance P modulates bone remodeling properties of murine osteoblasts and osteoclasts
Scientific Reports (Nature) Germany, 15 June 2018
Physiology
Key words: Substance P, bone remodeling, osteoblasts, osteoclasts, Bone, Mechanisms of disease [more]
Organism: Mouse
Cell Line: Osteoclast, Osteoblast
Synergistic Antitumor Effect of Oligogalacturonides and Cisplatin on Human Lung Cancer A549 Cells
International Journal of Molecular Sciences (MDPI) Taiwan, 14 June 2018
Oncology
Key words: adjuvant therapy, cisplatin, oligogalacturonides, synergistic effect [more]
Organism: Human
Pathological State: Cancer
Cell Line: A549 (Lung carcinoma cells)
Nerve Growth Factor (NGF)—Receptor Survival Axis in Head and Neck Squamous Cell Carcinoma
International Journal of Molecular Sciences (MDPI) Austria, 14 June 2018
Oncology
Key words: TissueFaxs, cell cycle arrest, cytokeratin, necrosis [more]
Organism: Human
Tissue: Mucosa
Pathological State: Cancer
Breast Cancer Histological Image Classification Using Fine-Tuned Deep Network Fusion
International Conference Image Analysis and Recognition (Springer) , 06 June 2018
Key words: Breast cancer Histological images Classification Deep learning
Targeted intracerebral delivery of the anti-inflammatory cytokine IL13 promotes alternative activation of both microglia and macrophages after stroke
Journal of Neuroinflammation (Springer) Germany, 04 June 2018
Immunology
Key words: Interleukin 13, Mesenchymal stem cells, Microglia/macrophage polarization, Neuroinflammation, Stroke [more]
Organism: Mouse
Tissue: Brain
Pathological State: Cerebral Ischemia
Novel Conducting and Biodegradable Copolymers with Noncytotoxic Properties toward Embryonic Stem Cells
ACS OMEGA (ACS Publications) Brazil, 31 May 2018
Stem Cell Research
Key words: Cell and Molecular biology, Conducting polymers, Environmental biology, Polyesters [more]
Organism: Human
Cell Line: Human embryonic stem cells (hESCs)
Hierarchical Multiplexing Nanodroplets for Imaging-Guided Cancer Radiotherapy via DNA Damage Enhancement and Concomitant DNA Repair Prevention
ACS NANO (ACS Publications) China, 29 May 2018
Nanomedicine
Key words: cancer radiotherapy, DNA damage and repair, hierarchical nanostructure, multimodal imaging, tumor hypoxia [more]
Organism: Mouse
Tissue: Allograft Tumor
Pathological State: Cancer
Acellular vascular matrix grafts from human placenta chorion: Impact of ECM preservation on graft characteristics, protein composition and in vivo performance
Biomaterials (Elsevier) Austria, 29 May 2018
Regenerative Medicine
Key words: Decellularized matrix, Human placenta, Small diameter vascular grafts, Cell migration, Biocompatibility [more]
Organism: Human
Tissue: Placenta
Identification of galectin-3 as an autoantigen in patients with IgG4-related disease
Journal of Allergy and Clinical Immunology (Elsevier) UK, USA, Italy, 29 May 2018
Immunology
Key words: IgG4-related disease, plasmablast, autoantigen, galectin-3, autoantibody [more]
Organism: Human
Tissue: Pancreas
Pathological State: IgG4-Related Disease
Allocation of Interferon Gamma mRNA Positive Cells in Caecum Hallmarks a Protective Trait Against Histomonosis
Frontiers in Immunology (Frontiers Media S.A.) Austria, 28 May 2018
Immunology
Key words: Histomonas meleagridis, histomonosis, image analysis, immunofluorescence, in situ hybridization, interferon gamma, interleukin-13, vaccination [more]
Organism: Turkey, Chicken
Tissue: Small Intestine, Liver, Spleen
Pathological State: Histomonosis
The overexpression of Fra1 disorders the inflammatory cytokine secretion by mTEC of myasthenia gravis thymus
Scandinavian journal of Immunology (Blackwell Publishing Inc.) China, 28 May 2018
Neuroscience
Key words: Fos-related antigen-1, inflammatory cytokine, medulla thymic epithelial cells, myasthenia gravis [more]
Organism: Human
Tissue: Thymus
Pathological State: Myasthenia Gravis
Therapeutic effects of dietary intervention on neuroinflammation and brain metabolism in a rat model of photothrombotic stroke
CNS Neuroscience and Therapeutics (Wiley) The Netherlands, 27 May 2018
Neuroscience
Key words: PET imaging, neuroinflammation, nutrition, photothrombotic stroke [more]
Organism: Rat
Tissue: Brain
Pathological State: Cerebral Ischemia
Decreased argininosuccinate synthetase expression in Thai patients with cholangiocarcinoma and the effects of ADI-PEG20 treatment in CCA cell lines
Oncology Letters (Spandidos Publications) Thailand, 24 May 2018
Oncology
Key words: Ki-67, arginine deprivation, argininosuccinate synthetase, cholangiocarcinoma, pegylated arginine deiminase [more]
Organism: Human
Tissue: Liver
Pathological State: Cancer
Cell Line: Cholangiocarcinoma cell lines (RmCCA-1 and HuCCA), human fibroblast cell line (BJ-1)
Cordycepin induces apoptosis of human ovarian cancer cells by inhibiting CCL5-mediated Akt/NF-κB signaling pathway
Cell Death Discovery (Nature) South Korea, USA, 23 May 2018
Oncology
Organism: Human
Pathological State: Cancer
Cell Line: SKOV-3 cells
BMP-2 restoration aids in recovery from liver fibrosis by attenuating TGF-β1 signaling
Laboratory Investigation (Nature) Taiwan, 22 May 2018
Hepathology
Key words: BMP-2, liver fibrosis, TGF-β1 signaling [more]
Organism: Human
Tissue: Liver
Pathological State: Liver Fibrosis, Liver Cirrhosis
Kinin and Purine Signaling Contributes to Neuroblastoma Metastasis
Frontiers in Pharmacology (Frontiers Media S.A.) Brazil, 18 May 2018
Oncology
Key words: bone marrow, bradykinin, metastasis, neuroblastoma, purinergic system [more]
Organism: Human
Pathological State: Cancer
Cell Line: CHP-100 cells
Lactobacillus casei Variety rhamnosus Probiotic Preventively Attenuates 5-Fluorouracil/Oxaliplatin-Induced Intestinal Injury in a Syngeneic Colorectal Cancer Model
Frontiers in Microbiology (Frontiers Media S.A.) Taiwan, 15 May 2018
Oncology
Key words: FOLFOX, Lactobacillus, apoptosis, gut microbiota, intestinal mucositis [more]
Organism: Mouse
Tissue: Allograft Tumor
Pathological State: Cancer
Catalpol inhibits migration and induces apoptosis in gastric cancer cells and in athymic nude mice
Biomedicine & Pharmacotherapy (Elsevier) China, 14 May 2018
Oncology
Key words: Gastric cancer, Catalpol, Migration, Apoptosis and ROS, DDP [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment
Cancer Cell (Cell Press) USA, 14 May 2018
Oncology
Key words: Olig2, Wnt, angiogenesis, astrocyte, blood-brain barrier, glioma, invasiveness, oligodendrocyte precursor, p53, vessel co-option [more]
Organism: Human, Mouse
Tissue: Brain, Xenograft Tumor
Pathological State: Cancer
Hematological findings in non-treated and gamma-irradiated mice deficient for MIC-1/GDF15.
Physiological Research (BioMed Central) Czech Republic, 10 May 2018
Hematology
Key words: GDF15 knockout mice, hematopoiesis, ionizing radiation, stress-induced cytokine [more]
Organism: Mouse
Tissue: Spleen, Bone
DNA damage predicts prognosis and treatment response in colorectal liver metastases superior to immunogenic cell death and T cells
Theranostics (Ivyspring International Publisher) Austria, 10 May 2018
Oncology
Key words: DNA damage, calreticulin, immunogenic cell death, colorectal liver metastases [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Regorafenib inhibits tumor progression through suppression of ERK/NF-κB activation in hepatocellular carcinoma bearing mice
Bioscience Reports (Kluwer Academic Publishers) Taiwan, 05 May 2018
Oncology
Key words: Bioluminescence imaging, Regorafenib, apoptosis, hepatocellular carcinoma, nuclear factor kappaB [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Effects of chitosan and chitosan N-acetylcysteine solutions on conjunctival epithelial cells
Journal of EuCornea (Elsevier) Austria, Serbia, 02 May 2018
Ophthalmology
Key words: Chitosan Chitosan-N-acetylcysteine Uptake Conjunctival epithelial cells Drug delivery [more]
Organism: Guinea Pig
Tissue: Eye
Rab37 in lung cancer mediates exocytosis of soluble ST2 and thus skews macrophages toward tumor‐suppressing phenotype
International Journal of Cancer (Wiley) Taiwan, 01 May 2018
Oncology
Key words: Rab37, ST2, exocytosis, macrophage, tumor microenvironment [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Eupatilin inhibits the proliferation of human esophageal cancer TE1 cells by targeting the Akt‑GSK3β and MAPK/ERK signaling cascades
Oncology Reports (Demetrios A. Spandidos Ed. and Pub.) China, 23 April 2018
Oncology
Key words: Eupatilin, human esophageal cancer, TE1 cells, Akt‑GSK3β, MAPK/ERK [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Blimp-1 prolongs allograft survival without regimen via influencing T cell development in favor of regulatory T cells while suppressing Th1
Molecular Immunology (Elsevier) Taiwan, 23 April 2018
Immunology
Key words: Allograft tolerance, B lymphocyte-induced maturation protein, T cells [more]
Organism: Mouse
Tissue: Skin
Pathological State: Allogeneic Transplantation
IL-33/ST2 axis mediates hyperplasia of intrarenal urothelium in obstructive renal injury
Experimental & Molecular Medicine (Nature) Taiwan, 20 April 2018
Nephrology
Key words: IL-33/ST2 axis, hyperplasia, renal injury, unilateral ureteral obstruction (UUO) [more]
Organism: Mouse
Tissue: Kidney
Pathological State: Acute Kidney Injury
Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal
CELL (Cell Press) UK, 19 April 2018
Oncology
Key words: branched evolution, cancer evolution, chromosome instability, deterministic evolution, intratumor heterogeneity, linear evolution, metastasis, punctuated evolution, renal cell cancer, tumor diversity [more]
Organism: Human
Tissue: Kidney
Pathological State: Cancer
Tumor-induced generation of splenic erythroblast-like Ter-cells promotes tumor progression
CELL (Cell Press) China, 19 April 2018
Oncology
Key words: Ter-119, Ter-cell, artemin, cancer immunotherapy, erythroblast-like, hepatocellular carcinoma, prognosis biomarker [more]
Organism: Mouse
Tissue: Liver
Pathological State: Cancer
Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal
CELL (Cell Press) UK, 19 April 2018
Oncology
Key words: chromosome instability, cytoreductive nephrectomy, evolution of metastasis, loss of 9p, metastasectomy, metastasis, oligometastasis, renal cell cancer, solitary metastasis [more]
Organism: Human
Tissue: Kidney
Pathological State: Cancer
Conditional depletion of GSK3b protects oligodendrocytes from apoptosis and lessens demyelination in the acute cuprizone model
GLIA (Wiley) USA, 18 April 2018
Neuroscience
Key words: GSK3b, cell death, glia, multiple sclerosis [more]
Organism: Mouse
Tissue: Brain
CD10 inhibits cell motility but expression is associated with advanced stage disease in colorectal cancer
Experimental & Molecular Medicine (Elsevier) UK, 11 April 2018
Oncology
Key words: CD10, NEP, CALLA, Colorectal cancer, Epithelial-mesenchymal transition, Metastasis [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Increased HOXA5 expression provides a selective advantage for gain of whole chromosome 7 in IDH wild-type glioblastoma
Genes and Development (Cold Spring Harbor Laboratory Press) USA, 09 April 2018
Oncology
Key words: glioblastoma, HoxA, homeobox RCAS, chromosome 7 gain [more]
Organism: Mouse
Tissue: Brain
Pathological State: Cancer
Photodynamic Effect of Methylene Blue and Low Level Laser Radiation in Head and Neck Squamous Cell Carcinoma Cell Lines
International Journal of Molecular Sciences (MDPI) Austria, 07 April 2018
Oncology
Key words: TissueFaxs, head and neck carcinoma, methylene blue, photodynamic therapy [more]
Organism: Human
Pathological State: Cancer
Cell Line: Detroit 562 cells (pharynx carcinoma)
The expansion in lymphoid organs of IL-4+ BATF+ T follicular helper cells is linked to IgG4 class switching in vivo
Life Science () USA, Japan, 05 April 2018
Immunology
Key words: T follicular helper (TFH), BATF+, IgG4 class switching, Sjögren's syndrome, secondary lymphoid organs [more]
Organism: Human
Tissue: Salivary Gland
Glycyrrhetinic Acid Antagonizes Pressure-Induced Venous Remodeling in Mice
Frontiers in Physiology (Frontiers Media S.A.) Germany, 04 April 2018
Physiology
Key words: endothelial cells, spider veins, venous hypertension, venous remodeling, wall stress [more]
Organism: Human
Cell Line: HUVEC, HUVSMC (human umbilical vein endothelial and SMCs)
Cordyceps militaris Extract Inhibits the NF-κB pathway and Induces Apoptosis through MKK7-JNK Signaling Activation in TK-10 Human Renal Cell Carcinoma
Natural Product Communications (SAGE Journals) South Korea, 01 April 2018
Oncology
Key words: Cordyceps militaris, Apoptosis, NF-κB, MKK7, JNK, TK-10 [more]
Organism: Human
Pathological State: Cancer
Cell Line: TK-10 renal cancer cell lines
Amentoflavone enhances the therapeutic efficacy of sorafenib by inhibiting anti-apoptotic potential and potentiating apoptosis in hepatocellular carcinoma in vivo
Anticancer Research (International Institute of Anticancer Research) Taiwan, 01 April 2018
Oncology
Key words: Amentoflavone sorafenib hepatocellular carcinoma ERK AKT apoptosis [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Periostin antisense oligonucleotide suppresses bleomycin‐induced formation of a lung premetastatic niche for melanoma
Cancer Science (Wiley) Japan, 31 March 2018
Oncology
Key words: antisense oligonucleotide, lung fibrosis, melanoma, periostin, premetastatic niche [more]
Organism: Mouse
Tissue: Lung
MRI‐guided interventional natural killer cell delivery for liver tumor treatment
Cancer Medicine (Wiley) USA, 30 March 2018
Oncology
Key words: Adoptive transfer immunotherapy, hepatocellular carcinoma, interventional oncology, magnetic resonance imaging, natural killer cell [more]
Organism: Rat
Tissue: Liver
Pathological State: Cancer
Collagen morphology influences macrophage shape and marker expression in vitro
Journal of Immunology and Regenerative Medicine (Elsevier) The Netherlands, 30 March 2018
Immunology
Key words: Extracellular matrix, Collagen type I, Pulmonary fibrosis, Ym1, CD206, Migration [more]
Organism: Human
Cell Line: Alveolar-like Makrophhages
Olaparib is effective in combination with, and as maintenance therapy after, first‐line endocrine therapy in prostate cancer cells
Molecular Oncology (Wiley) Austria, 15 March 2018
Oncology
Key words: PARP inhibition, combination therapy, endocrine therapy, maintenance therapy, olaparib, prostate cancer [more]
Organism: Human
Pathological State: Cancer
Cell Line: LNCaP-abl (Prostate carcinoma cell lines)
Loss of Neuroglobin Expression Alters Cdkn1a/Cdk6-Expression Resulting in Increased Proliferation of Neural Stem Cells
Stem Cells and Development (Mary Ann Liebert Inc.) Belgium, Germany, 15 March 2018
Stem Cell Research
Key words: neuroglobin – cell cycle – transcriptomics – neural stem cells [more]
Organism: Mouse
Cell Line: Neural stem cells
Effects of iota-carrageenan on ocular Chlamydia trachomatis infection in vitro and in vivo
Journal of Applied Phycology (Kluwer Academic Publishers) Austria, 13 March 2018
Microbiology
Key words: Carrageenan, Trachoma, Natural products, Chlamydia [more]
Organism: Human
Pathological State: Chlamydia Infection
Cell Line: HCjE cells (human corneal-limbal and conjunctival epithelial cell line)
Prostaglandin E2 Is Required for BMP4-Induced Mesoderm Differentiation of Human Embryonic Stem Cells
Stem Cell Reports (Cell Press) China, 13 March 2018
Stem Cell Research
Key words: prostaglandin E2, cyclooxygenase-1, BMP4, mesoderm, differentiation, human embryonic stem cells, β-catenin, [more]
Organism: Human
Cell Line: WA01 and WA09 hESCs
Atlas of the Striatum and Globus Pallidus in the Tree Shrew: Comparison with Rat and Mouse
Neuroscience Bulletin (Springer) China, 05 March 2018
Neuroscience
Key words: Striatum, Globus pallidus, Basal ganglia, Reconstruction, Rodent, Parvalbumin [more]
Organism: Tree Shrew
Tissue: Brain
Novel platforms of multiplexed immunofluorescence for study of paraffin tumor tissues
Journal of Cancer Treatment and Diagnosis (Sciaccess Publishers) USA, 01 March 2018
Cytometry
Key words: Multiplexed proteins identification Immunofluorescence Signal Amplification Spatial Cell Distribution Image Analysis
4:20 PM Abstract No. 350 Interferon-gamma-eluting microspheres for MRI-guided immunotherapy of liver cancer
Journal of Vascular and Interventional Radiology (Elsevier) USA, 01 March 2018
Oncology
Organism: Rabbit
Tissue: Liver
Pathological State: Cancer
In vitro behavior of human mesenchymal stem cells on poly(N-isopropylacrylamide) based biointerfaces obtained by matrix assisted pulsed laser evaporation
Applied Surface Science (Elsevier) Romania, 28 February 2018
Cell Biology
Key words: pNIPAM coatings, MAPLE, mesenchymal stem cells [more]
Organism: Human
Cell Line: Human mesenchymal stem cells (hMSCs)
[18F]FEPPA: Improved Automated Radiosynthesis, Binding Affinity, and Preliminary in Vitro Evaluation in Colorectal Cancer
ACS Medicinal Chemistry Letters (ACS Publications) Austria, 21 February 2018
Radiotherapy
Key words: Affinity, autoradiography, colorectal cancer, FEPPA, radiosynthesis, TSPO [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
CXCL5 facilitates melanoma cell-neutrophil interaction and lymph node metastasis
Journal of Investigative Dermatology (Elsevier) Austria, 21 February 2018
Dermatology
Key words: CXCL5, melanoma cells, chemokine mRNA expression [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Hypoxia-Preconditioned Human Umbilical Vein Endothelial Cells Protect Against Neurovascular Damage After Hypoxic Ischemia in Neonatal Brain
Molecular Neurobiology (Springer) Taiwan, 19 February 2018
Neuroscience
Key words: Neonatal brain injury, neurovascular protection, hypoxia-preconditioned, human umbilical vein endothelial cells, hypoxia-inducible factor 1-alpha [more]
Organism: Human
Cell Line: HUVECs (Human umbilical vein endothelial cells)
Inflammatory Monocytes Drive Influenza A Virus–Mediated Lung Injury in Juvenile Mice
The Journal of Immunology (American Association of Immunologists) USA, 14 February 2018
Immunology
Key words: Influenza A virus (IAV), NLRP3 inflammasome, cytokines, monocytes [more]
Organism: Mouse
Tissue: Lung, Heart
Preclinical In Vitro and In Vivo Evaluation of [18F]FE@SUPPY for Cancer PET Imaging: Limitations of a Xenograft Model for Colorectal Cancer
Contrast Media and Molecular Imaging (Wiley) Austria, 13 February 2018
Oncology
Key words: [18F]FE@SUPPY, Cancer PET Imaging, Colorectal Cancer [more]
Organism: Mouse
Tissue: Colon
Pathological State: Cancer
Calcium signaling mediates five types of cell morphological changes to form neural rosettes
Journal of Cell Science (The Company of Biologists) Czech Republic, 12 February 2018
Neuroscience
Key words: Embryonic stem cells, neural stem cell niche, neural rosette formation, calcium, neurogenesis, adherens junctions, cytoskeleton proteins [more]
Organism: Human
Cell Line: Human ESC-derived neural rosettes
Functional loss of p53 cooperates with the in vivo microenvironment to promote malignant progression of gastric cancers
Scientific Reports (Nature) Japan, 02 February 2018
Oncology
Key words: Gastric cancer, p53 mutations, tumour-suppressor proteins [more]
Organism: Mouse
Tissue: Stomach
Pathological State: Cancer
Angiogenin Attenuates Scar Formation in Burn Patients by Reducing Fibroblast Proliferation and Transforming Growth Factor β1 Secretion
Annals of Plastic Surgery (LWW Journals) Taiwan, 01 February 2018
Regenerative Medicine
Key words: angiogenin, fibroblast, scar, Smad2, transforming growth factor β1 [more]
Organism: Human
Tissue: Skin
Pathological State: Burn Wound
Differentiation-associated urothelial cytochrome P450 oxidoreductase predicates the xenobiotic-metabolizing activity of “luminal” muscle-invasive bladder cancers
Molecular Carcinogenesis (Wiley) UK, 01 February 2018
Oncology
Key words: Urothelium, carcinogens, normal human urothelial (NHU) cells, EROD activity [more]
Organism: Human
Cell Line: NHU cells (Normal human urothelial)
Grey matter OPCs are less mature and less sensitive to IFNγ than white matter OPCs: consequences for remyelination
Scientific Reports (Nature) The Netherlands, 01 February 2018
Neuroscience
Key words: Multiple sclerosis (MS), central nervous system, oligodendrocyte progenitor cells (OPCs) [more]
Organism: Rat
Cell Line: OPS cells (Oligodendrocyte progenitor cells)
Assessing the selective therapeutic efficacy of superparamagnetic erlotinib nanoparticles in lung cancer by using quantitative magnetic resonance imaging and a nuclear factor kappa-B reporter gene system
Nanomedicine: Nanotechnology, Biology and Medicine (Elsevier) Taiwan, 31 January 2018
Nanomedicine
Key words: Erlotinib, superparamagnetic iron oxide, magnetic resonance imaging, nuclear factor-κBNon-small-cell lung cancer [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Expression of cystatin C in the female reproductive tract and its effect on human sperm capacitation
Reproductive Biology and Endocrinology (Springer) Taiwan, 30 January 2018
Reproductive Medicine
Key words: Cystatin C (CST3), seminal plasma, sperm protein tyrosine phosphorylation [more]
Organism: Human
Tissue: Uterus
SPK1-transfected UCMSC has better therapeutic activity than UCMSC in the treatment of experimental autoimmune encephalomyelitis model of Multiple sclerosis
Scientific Reports (Nature) China, 29 January 2018
Neuroscience
Key words: Multiple Sclerosis (MS), central nervous system, permanent neurological damage, cytokine [more]
Organism: Human
Cell Line: Human umbilical cord mesenchymal stem cells (HUC-MSC-SPK1)
AXL promotes Zika virus infection in astrocytes by antagonizing type I interferon signalling
Nature Microbiology (Nature) China, 29 January 2018
Microbiology
Key words: Zika virus (ZIKV), neonatal microcephaly, Guillain–Barré syndrome, AXL [more]
Organism: Mosquito
Pathological State: Zika Virus Infection, Guillain–Barré syndrome
Cell Line: C6/36 cells
Histamine drives severity of innate inflammation via histamine 4 receptor in murine experimental colitis
Mucosal Immunology (Nature) USA, 24 January 2018
Immunology
Organism: Mouse
Tissue: Colon
Pathological State: Colitis
Injectable hydroxyphenyl derivative of hyaluronic acid hydrogel modified with RGD as scaffold for spinal cord injury repair
Journal of Biomedical Materials Research (Wiley) Czech Republic, 23 January 2018
Regenerative Medicine
Key words: Hydrogel, spinal cord injury (SCI), hydroxyphenyl derivative of hyaluronic acid (HA-PH) [more]
Organism: Rat
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
CCR5/CCL5 axis interaction promotes migratory and invasiveness of pancreatic cancer cells
Scientific Reports (Nature) USA, 22 January 2018
Oncology
Key words: Pancreatic cancer (PC), CCR5, CCL5, F-actin polymerization [more]
Organism: Human
Tissue: Pancreas
Pathological State: Cancer
Posterior reversible encephalopathy syndrome in stroke-prone spontaneously hypertensive rats on high-salt diet
Journal of Cerebral Blood Flow and Metabolism (SAGE Journals) USA, 19 January 2018
Oncology
Key words: Animal models, hypertension, posterior cerebral reversible encephalopathy, cerebral blood flow, white matter [more]
Organism: Rat
Tissue: Brain
Pathological State: Encephalopathy
Simvastatin induces G1 arrest by up-regulating GSK3β and down-regulating CDK4/cyclin D1 and CDK2/cyclin E1 in human primary colorectal cancer cells
Journal of Cellular Physiology (Wiley) Taiwan, 15 January 2018
Oncology
Key words: Simvastatin (SIM), colorectal cancer (CRC), CDK4/cyclin D1 [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Canine macrophages can like human macrophages be in vitro activated toward the M2a subtype relevant in allergy
Developmental & Comparative Immunology (Elsevier) Austria, 10 January 2018
Immunology
Key words: Allergy, canine, comparative, DH82M1 macrophage, M2a macrophage, polarization [more]
Organism: Dog, Human
Pathological State: Cancer
Cell Line: U937 and DH82 cells (Makrophage like cells)
Formation of nanotubular TiO2 structures with varied surface characteristics for biomaterial applications
Journal of Biomedical Materials Research (Wiley) Colombia, 09 January 2018
Biological Materials
Key words: Anodization, titanium, nanotubular TiO2, counterion [more]
Organism: Human
Cell Line: Adipose tissue derived stromal cells (ADSC)
Physical-chemical characterization and biological assessment of simple and lithium-doped biological-derived hydroxyapatite thin films for a new generation of metallic implants
Applied Surface Science (Elsevier) Romania, Turkey, 06 January 2018
Regenerative Medicine
Key words: Biological-derived hydroxyapatite, Lithium doping, Pulsed Laser Deposition, Sustainable resources, In vitro assessment [more]
Organism: Human
Cell Line: Human mesenchymal stem cells (hMSCs)
Does combined therapy of curcumin and epigallocatechin gallate have a synergistic neuroprotective effect against spinal cord injury?
Neural Regeneration Research (Publishing House of Neural Regeneration Research) Czech Republic, USA, 01 January 2018
Regenerative Medicine
Key words: spinal cord injury, epigallocatechin gallate, curcumin, inflammatory response, neural regeneration [more]
Organism: Rat
Tissue: Spinal Cord
Pathological State: Spinal Cord Injury
Zinc finger protein 143 expression is closely related to tumor malignancy via regulating cell motility in breast cancer
BMB Reports (NCBI) South Korea, 31 December 2017
Oncology
Key words: Invasive ductal carcinoma, Metastasis, Motility, ZNF143 [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
AKT3 drives adenoid cystic carcinoma development in salivary glands
Cancer Medicine (Wiley) Austria, 28 December 2017
Oncology
Key words: AKT3, adenoid cystic carcinoma, MMTV-tTA mouse model, oncogene addiction, salivary gland cancer [more]
Organism: Mouse
Tissue: Salivary Gland
Pathological State: Cancer
A benchmark for comparing precision medicine methods in thyroid cancer diagnosis using tissue microarrays
Bioinformatics (Oxford University Press) Taiwan, USA, Japan, 23 December 2017
Biological Methods
Key words: precision medicine, cancer diagnosis, tissue microarray [more]
Organism: Human
Tissue: Thyroid
Pathological State: Cancer
Actein induces autophagy and apoptosis in human bladder cancer by potentiating ROS/JNK and inhibiting AKT pathways
Oncotarget (Impact Journals) China, 22 December 2017
Oncology
Key words: human bladder cancer, Actein (ACT), autophagy and apoptosis, ROS and JNK, AKT [more]
Organism: Mouse, Human
Tissue: Xenograft Tumor, Liver, Lung, Kidney
Pathological State: Cancer
Recurrent infection progressively disables host protection against intestinal inflammation
Science (American Association for the Advancement of Science) USA, Germany, 22 December 2017
Immunology
Key words: Recurrent infection, host protection, intestinal inflammation [more]
Organism: Mouse
Tissue: Small Intestine, Colon
Pathological State: Intestinal Inflammation
CD151, A Novel Host Factor of Nuclear Export Signaling in Influenza Virus Infection
Journal of Allergy and Clinical Immunology (Elsevier) Singapore, 21 December 2017
Immunology
Key words: Influenza A virus (IAV), CD151, nuclear export, host innate immunity, inflammasome, IAV severity [more]
Organism: Mouse
Tissue: Lung
Pathological State: Influenza Infection
Renal allograft rejection, lymphocyte infiltration, and de novo donor-specific antibodies in a novel model of non-adherence to immunosuppressive therapy
BMC Immunology (BioMed Central) Germany, 19 December 2017
Immunology
Key words: Donor specific antibodies, humoral rejection, renal transplantation, non-adherence, leukocyte infiltration, BAFF [more]
Organism: Rat
Tissue: Kidney
Pathological State: Organ Transplantation
Mitochondrial ROS activates ERK/autophagy pathway as a protected mechanism against deoxypodophyllotoxin-induced apoptosis
Oncotarget (Impact Journals) South Korea, USA, 19 December 2017
Oncology
Key words: Deoxypodophyllotoxin, apoptosis, autophagy, mitochondrial ROS, ERK [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Magnolol inhibits venous remodeling in mice
Scientific Reports (Nature) Germany, 19 December 2017
Cardiology
Key words: Magnolol, venous vasculature, endothelial cells, varicose/spider veins, peripheral vascular disease [more]
Organism: Human
Cell Line: HUVECs (Human umbilical vein endothelial cells)
Novel Hydrogel-Advanced Modified Clay Nanocomposites as Possible Vehicles for Drug Delivery and Controlled Release
Nanomaterials (MDPI) Romania, 13 December 2017
Nanomedicine
Key words: hydrogel, clay, nanocomposites, biocompatibility [more]
Organism: Cattle
Cell Line: HT29 and MDBK cells
18F-FDG PET Biomarkers Help Detect Early Metabolic Response to Irreversible Electroporation and Predict Therapeutic Outcomes in a Rat Liver Tumor Model
Radiology (Radiological Society of North America) USA, China, 12 December 2017
Radiotherapy, Oncology
Key words: 18F-FDG PET, Biomarkers, Metabolic Response, Irreversible Electroporation, Liver Tumor [more]
Organism: Rat
Tissue: Liver
Pathological State: Cancer
Comparison of MOLLI, shMOLLLI, and SASHA in discrimination between health and disease and relationship with histologically derived collagen volume fraction
European Heart Journal (Oxford University Press) UK, Germany, Spain, 11 December 2017
Cardiology
Key words: T1 mapping, MOLLI, shMOLLI, SASHA, collagen, aortic valve stenosis, myocardium, troponin, myocardial fibrosis, collagen, respiratory care units, therapeutic equivalency, transverse spin relaxation time [more]
Organism: Human
Tissue: Heart
Pathological State: Cardiac Fibrosis
INO80 haploinsufficiency inhibits colon cancer tumorigenesis via replication stress-induced apoptosis
Oncotarget (Impact Journals) South Korea, 06 December 2017
Oncology
Key words: INO80 chromatin remodeling complex, colon cancer, APC Min mouse model, replication stress, apoptosis [more]
Organism: Mouse
Tissue: Small Intestine, Colon
Pathological State: Cancer
Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer
Scientific Reports (Nature) Taiwan, 05 December 2017
Oncology
Key words: Phosphorylation, cancer therapeutic resistance, Cdc7-Dbf4 kinase, stress [more]
Organism: Human
Tissue: Mucosa
Pathological State: Cancer
Nocturnal resveratrol administration inhibits chemically induced breast cancer formation in rats
JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (Polish Physiological Society) Slovakia, Austria, 01 December 2017
Oncology
Key words: resveratrol, circadian rhythm, carcinogenesis, breast cancer, immunity, reactive oxygen species [more]
Organism: Rat
Tissue: Breast
Pathological State: Cancer
IgE autoreactivity in bullous pemphigoid: eosinophils and mast cells as major targets of pathogenic immune reactants
British Journal of Dermatology (Wiley) Austria, 28 November 2017
Dermatology
Key words: Bullous pemphigoid (BP), urticarial eruptions, IgG, IgE [more]
Organism: Human
Tissue: Skin
Pathological State: Bullous Pemphigoid
Interaction of factor VII activating protease (FSAP) with neutrophil extracellular traps (NETs)
Thrombosis Research (Elsevier) Austria, Germany, Norway, 21 November 2017
Cell Biology
Key words: NETs, FSAP, thrombosis, inflammation [more]
Organism: Human
Tissue: Blood Vessels
Analysis of anti-TNF-induced skin lesions reveals strong Th1 activation with some distinct immunological characteristics
British Journal of Dermatology (Wiley) Austria, USA, 16 November 2017
Dermatology
Key words: Psoriasiform, eczematous eruptions, anti-TNF-α therapy, IFN-γ [more]
Organism: Human
Tissue: Skin
Pathological State: Crohn's Disease, Colitis, Rheumatoid Arthritis, Psoriasis, Eczema
Chronic Stress Alters Striosome-Circuit Dynamics, Leading to Aberrant Decision-Making
CELL (Cell Press) USA, 16 November 2017
Neuroscience
Key words: Striatum, basal ganglia, cost-benefit, prefrontal cortex, optogenetics, prelimbic cortex, parvalbumin-positive interneurons, fast-spiking interneuron, sexcitation-inhibition balance [more]
Organism: Rat
Tissue: Brain
Phospholipase D inhibitors reduce human prostate cancer cell proliferation and colony formation
British Journal of Cancer (Nature) UK, 14 November 2017
Oncology
Key words: Phospholipases, mTOR, PKB/Akt, prostate cancer (PCa), benign prostatic hyperplasia (BPH) [more]
Organism: Human
Tissue: Kidney, Prostate
Pathological State: Cancer
Controlled release of liposome-encapsulated temozolomide for brain tumour treatment by convection-enhanced delivery
Journal of Drug Targeting (Taylor and Francis) Taiwan, 14 November 2017
Oncology
Key words: Convention-enhanced delivery, drug delivery, liposome, temozolomide, brain tumour [more]
Organism: Mouse
Tissue: Brain
Pathological State: Cancer
Analysis of the Human Mucosal Response to Cholera Reveals Sustained Activation of Innate Immune Signaling Pathways
Infection and Immunity (American Society for Microbiology) USA, 13 November 2017
Immunology
Key words: Vibrio cholerae infection, cholera, Caco-2 or THP-1 cells [more]
Organism: Human
Tissue: Small Intestine
Pathological State: Cholera
Digital image analysis in breast pathology—from image processing techniques to artificial intelligence
Translational Research (Elsevier) Sweden, 07 November 2017
Oncology
Key words: Breast cancer, histopathology, biomarker, artificial intelligence (AI) [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
Cyclin D1 promoter -56 and -54 bp CpG un-methylation predicts invasive progression in arsenic-induced Bowen's disease
Journal of Dermatological Science (Elsevier) Taiwan, 31 October 2017
Oncology
Key words: Arsenic-induced Bowen's disease, cyclin D1 un-methylation, aneuploidy, predictor, invasive progression [more]
Organism: Human
Tissue: Skin
Pathological State: Bowen's Disease, Cancer
HER2 challenge contest: a detailed assessment of automated HER2 scoring algorithms in whole slide images of breast cancer tissues
Histopathology (Wiley) UK, 27 October 2017
Medical Image Analysis
Key words: Human epidermal growth factor receptor 2 (HER2), IHC, invasive breast cancer (BCa)
CCR7 Is Important for Mesangial Cell Physiology and Repair
Journal of Histochemistry & Cytochemistry (SAGE Journals) Germany, 27 October 2017
Oncology
Key words: Homeostatic chemokine receptor CCR7, human mesangial cells, glomerulogenesis, mesangial biology [more]
Organism: Mouse
Tissue: Kidney
Guanylate-binding protein 2 regulates Drp1-mediated mitochondrial fission to suppress breast cancer cell invasion
Cell Death & Disease (Nature) China, 26 October 2017
Oncology
Key words: Guanylate-binding protein 2 (GBP2), interferon-γ (IFN-γ), mitochondrial fission, shRNA [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
The Pericytic Phenotype of Adipose Tissue-derived Stromal Cells is Promoted by NOTCH2
Stem Cells (Wiley) Germany, The Netherlands, 25 October 2017
Stem Cell Research
Key words: Diabetic retinopathy (DR), adipose tissue‐derived stromal cells (ASC), NOTCH2, human umbilical cord vein endothelial cells (HUVEC) [more]
Organism: Human
Cell Line: HUVECs (Human umbilical vein endothelial cells)
The natural compound 2,3,5,4′-tetrahydroxystilbene-2-O-β-d glucoside protects against adriamycin-induced nephropathy through activating the Nrf2-Keap1 antioxidant pathway
Environmental Toxicology (Wiley) Taiwan, 24 October 2017
Toxicology
Key words: Tetrahydroxystilbene-2-O-β-d-glucoside (THSG), Polygoni Multiflori, adriamycin (AD), quinone oxidoreductase (NQO)-1 [more]
Organism: Mouse
Tissue: Kidney
Initial graft size and not the innate immune response limit survival of engrafted neural stem cells
Journal of Tissue Engineering and Regenerative Medicine (Wiley) Germany, 22 October 2017
Neuroscience
Key words: Transplantation of neural stem cells (NSCs), Luc2 and copGFP, bioluminescence imaging (BLI) [more]
Organism: Mouse
Tissue: Brain
Tumor angiogenesis and bone metastasis - Correlation in invasive breast carcinoma
Journal of Immunological Methods (Elsevier) USA, 21 October 2017
Oncology
Key words: Breast carcinoma, bone metastasis, tumor angiogenesis, pathological biomarkers [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
The non-canonical ubiquitin activating enzyme UBA6 suppresses epithelial-mesenchymal transition of mammary epithelial cells
Oncotarget (Impact Journals) USA, 20 October 2017
Oncology
Key words: ubiquitination, breast cancer, EMT, Rho GTPase, cell cycle [more]
Organism: Human
Cell Line: MCF-10A cells
TDP-43 proteolysis is associated with astrocyte reactivity after traumatic brain injury in rodents
Journal of Neuroimmunology (Elsevier) Taiwan, 20 October 2017
Neuroscience
Key words: Astrocyte, astrogliosis, traumatic brain injury, transactivation response DNA-binding protein 43 [more]
Organism: Rat
Tissue: Brain
Pathological State: Traumatic Brain Injury
Human alternative Klotho mRNA is a nonsense-mediated mRNA decay target inefficiently spliced in renal disease
The Journal of Clinical Investigation (American Society for Clinical Investigation) The Netherlands, 19 October 2017
Nephrology
Key words: Aging, Nephrology, Chronic kidney disease, RNA processing [more]
Organism: Human
Pathological State: Kidney Disease
Cell Line: HK-2 cells
Cordycepin promotes apoptosis in renal carcinoma cells by activating the MKK7-JNK signaling pathway through inhibition of c-FLIPL expression
PLoS One (PLOS) South Korea, 18 October 2017
Oncology
Key words: Cellular FLICE inhibitory protein (c-FLIP), NF-κB, apoptosis, cordycepin [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
DNA-binding of the Tet-transactivator curtails antigen-induced lymphocyte activation in mice
Nature Communications (Nature) Austria, Australia, 18 October 2017
Immunology
Key words: Tet-On/Off system, BCL2 overexpression, CRISPR/Cas9, RNA interference (RNAi) [more]
Organism: Mouse
Tissue: Spleen
Lactobacillus gasseri attenuates allergic airway inflammation through PPARγ activation in dendritic cells
Journal of Molecular Medicine (Springer) Taiwan, 14 October 2017
Allergy Research
Key words: Allergy asthma, lactic acid bacillus, peroxisome proliferator-activated receptor gamma (PPARγ), dendritic cells [more]
Organism: Mouse
Tissue: Lung
Pathological State: Asthma
GD1a Overcomes Inhibition of Myelination by Fibronectin via Activation of Protein Kinase A: Implications for Multiple Sclerosis
Journal of Neuroscience (SFN) The Netherlands, 11 October 2017
Neuroscience
Key words: Fibronectin, ganglioside, multiple sclerosis, oligodendrocyte, remyelination [more]
Organism: Mouse
Tissue: Brain
Actein induces apoptosis in leukemia cells through suppressing RhoA/ROCK1 signaling pathway
International Journal of Oncology (Spandidos Publications) China, 10 October 2017
Oncology
Key words: Actein, apoptosis, leukemia, RhoA/ROCK1 signaling pathway [more]
Organism: Mouse
Pathological State: Cancer
Therapeutic Effects of Monoclonal Antibody against Dengue Virus NS1 in a STAT1 Knockout Mouse Model of Dengue Infection
The Journal of Immunology (American Association of Immunologists) Taiwan, 10 October 2017
Immunology
Key words: Dengue virus (DENV), dengue fever, DENV nonstructural protein 1 (NS1) [more]
Organism: Mouse
Tissue: Skin
Pathological State: Dengue Virus Infection
Linarin sensitizes tumor necrosis factor-related apoptosis (TRAIL)-induced ligand-triggered apoptosis in human glioma cells and in xenograft nude mice
Biomedicine & Pharmacotherapy (Elsevier) China, 06 October 2017
Oncology
Key words: TRAIL, glioma, linarin (LIN), apoptosis, ROS generation [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
PD-1 Expression in Head and Neck Squamous Cell Carcinomas Derives Primarily from Functionally Anergic CD4+ TILs in the Presence of PD-L1+ TAMs
Cancer Research (AACR Publications) USA, 25 September 2017
Oncology
Key words: Oral tongue squamous cell carcinoma (OTSCC), PD-1, tumor microenvironment (TME), tumor-infiltrating lymphocytes (TIL) [more]
Organism: Human
Tissue: Head and Neck
Pathological State: Cancer
The microRNA ame-miR-279a regulates sucrose responsiveness of forager honey bees (Apis mellifera)
Insect Biochemistry and Molecular Biology (Elsevier) USA, China, 20 September 2017
Zoology
Key words: microRNA, honey bee, proboscis extension reflex, sucrose responsiveness, division of labour [more]
Organism: Honey Bee
Tissue: Brain
Axonal components of nerves innervating the human arm
Annals of Neurology (Wiley) Austria, 20 September 2017
Neuroscience
Key words: Nerves, sensory and motir axons, spinal cord, neurofilament [more]
Organism: Human
Tissue: Nerves
Role of BDNF and neurotrophic receptors in human inner ear development
Cell and Tissue Research (Springer) Austria, Seweden, 19 September 2017
Developmental Biology
Key words: Inner ear, Human, BDNF, Neurotrophin receptors, In situ hybridization [more]
Organism: Human
Tissue: Bone