Customer Publications (A total of 2648 papers published)
In silico analyses of pan-squamous cell carcinoma unveiled the immunological implications of MRPL13, which had previously been under-recognized
Heliyon (Cell Press) China, 14 December 2023
Oncology
Key words: MRPL13, Pan-squamous cell carcinoma, Bioinformatics analysis, Prognostic. CD8+ T-cell infiltration [more]
Organism: Human
Pathological State: Cancer
Chlamydia suis survival in dust: First insights–A short communication
Research in Veterinary Science (Elsevier) Austria, 13 December 2023
Microbiology
Key words: Chlamydia suis, Pigs, Dust, Transmission, Disinfection, Viability [more]
Pathological State: Chlamydia infection
Cell Line: LLC-MK2 cells (Rhesus monkey kidney cell line)
ERK1/2 Phosphorylation Predicts Survival in Recurrent Glioblastoma Following Intracerebral and Adjuvant PD-1/CTLA-4 Immunotherapy: A REMARK-Guided Analysis
Clinical Cancer Research (AACR) Belgium, USA, Mexico, 13 December 2023
Oncology, Pharmacology
The role of EDIL3 in maintaining cartilage extracellular matrix and inhibiting osteoarthritis development
Bone & Joint Research (The British Editorial Society of Bone & Joint Surgery) Taiwan, 12 December 2023
Osteology
Key words: Osteoarthritis, EDIL3, Chondrocyte, Extracellular matrix, Cartilage, osteoarthritic changes, cartilage tissues, extracellular matrix, chondrocytes, antibodies, interleukin, aggrecan, pro-inflammatory cytokines, OARSI, subchondral bone plate [more]
Organism: Human
Tissue: Bone
Pathological State: Osteoarthritis
Corynoline inhibits esophageal squamous cell carcinoma growth via targeting Pim-3
Phytomedicine (Elsevier) China, 12 December 2023
Oncology, Pharmacology
Key words: Proviral integration site for maloney murine leukemia virus 3, corynoline, esophageal squamous cell carcinoma, proliferation, apoptosis [more]
Organism: Human
Tissue: Esophagus
Pathological State: Cancer
Differential impact of cytoplasmic vs. nuclear RAD51 expression on breast cancer progression and patient prognosis
International Journal of Oncology (Spandios Publications) Taiwan, 07 December 2023
Oncology, Molecular Biology
Organism: Human
Tissue: Breast
Pathological State: Cancer
Pro‐inflammatory cytokine IL‐6 regulates LMO4 expression in psoriatic keratinocytes via AKT/STAT3 pathway
Immunity, Inflammation and Disease (Wiley Online Library) China, 06 December 2023
Dermatology, Molecular Biology
Key words: AKT, interleukin‐6, LMO4, psoriasis, STAT3 [more]
Organism: Human
Tissue: Skin
Pathological State: Psoriasis
Cell Line: HaCaT cells
Tumor-immune microenvironment and NRF2 associate with clinical efficacy of PD-1 blockade combined with chemotherapy in lung squamous cell carcinoma
Cell Reports Medicine (Cell Press) China, 04 December 2023
Oncology, Pharmacology
Key words: squamous NSCLC, PD-1 blockade, biomarkers PD-L1, tumor mutational burden, gene expression signature, NRF2, tislelizumab clinical trial, immunotherapy [more]
Organism: Human
Tissue: Lung
Pathological State: Cancer
SAD rats: Effects of short photoperiod and carbohydrate consumption on sleep, liver steatosis, and the gut microbiome in diurnal grass rats
Chronobiology International (Taylor & Francis) USA, 04 December 2023
Nutritional science, Gastroenterology
Key words: Photoperiod, seasonal affective disorder, metabolic dysbiosis, non-alcoholic fatty liver disease [more]
Organism: Rat
Tissue: Liver
Pathological State: Liver steatosis (fatty liver)
Excessive Lipid Peroxidation in Uterine Epithelium Causes Implantation Failure and Pregnancy Loss
Advanced Science (Wiley) China, 03 December 2023
Reproductive Medicine
Organism: Mouse
Tissue: Uterus
Pathological State: Excessive Lipid Peroxidation
Dihydromyricetin alleviates inflammatory bowel disease associated intestinal fibrosis by inducing autophagy through the PI3K/AKT/mTOR signaling pathway
Naunyn-Schmiedeberg's Archives of Pharmacology (Springer) China, 02 December 2023
Gastroenterology, Pharmacology
Key words: Autophagy, Dihydromyricetin, Inflammatory bowel disease, Intestinal fibrosis [more]
Organism: Mouse
Tissue: Colon
Pathological State: Intestinal fibrosis associated with inflammatory bowel disease (IBD)
Spatiotemporal characterization of glial cell activation in an Alzheimer's disease model by spatially resolved transcriptomics
Experimental & Molecular Medicine (Nature) South Korea, 01 December 2023
Neuroscience
Key words: Alzheimer's disease, Transcriptomics, Translational research [more]
Organism: Mouse
Tissue: Brain
Pathological State: Alzheimer's Disease
Downregulation of N4-acetylcytidine modification in myeloid cells attenuates immunotherapy and exacerbates hepatocellular carcinoma progression
British Journal of Cancer (Nature) China, 01 December 2023
Oncology, Pharmacology
Key words: Cancer immunotherapy, Translational research
Low oral dose of 4-methylumbelliferone reduces glial scar but is insufficient to induce functional recovery after spinal cord injury
Scientific Reports (Nature) Czech Republic, UK, 29 November 2023
Neuroscience, Pharmacology
Key words: Molecular neuroscience, Regeneration and repair in the nervous system, Synaptic plasticity [more]
Organism: Rat
Tissue: Spinal Cord
Pathological State: Spinal cord injury
Glucocorticoid treatment influences prostate cancer cell growth and the tumor microenvironment via altered glucocorticoid receptor signaling in prostate fibroblasts
Oncogene (Nature) Austria, Germany, 28 November 2023
Oncology, Pharmacology
Key words: Extracellular matrix, Extracellular signalling molecules, Hormone receptors, Prostate cancer [more]
Organism: Human
Tissue: Prostate
Pathological State: Cancer
Low-intensity exercise training increases systolic function of heart and MHCII low cardiac resident macrophages
Heliyon (Cell Press) China, 28 November 2023
Cardiology
Key words: Cardiac macrophage, Ejection fraction, Heart, Low-intensity exerciseInnate immunity [more]
Organism: Mouse
Tissue: Heart
Diverse macrophage populations contribute to distinct manifestations of human cutaneous graft-versus-host disease
British Journal of Dermatology (Oxford Academic) Austria, UK, 27 November 2023
Immunology, Dermatology
Organism: Human
Tissue: Skin
Pathological State: Graft-versus-Host Disease
A prognostic model based on Scissor+ cancer associated fibroblasts identified from bulk and single cell RNA sequencing data in head and neck squamous cell carcinoma
Cellular Signalling (Elsevier) China, 27 November 2023
Oncology
Organism: Human
Tissue: Head and Neck
Pathological State: Cancer
Analysis of cells of epithelial, connective tissue and immune differentiation in HPV-positive-, HPV-negative oropharyngeal carcinoma and normal oropharyngeal tissue by immunofluorescence multiplex image cytometry: a preliminary report
BMC cancer (Springer) Austria, USA, 27 November 2023
Oncology, Cell Biology
Key words: Image cytometry, Fluorescent antibody technique, Epithelial cells, Connective tissue, Leukocytes, Oropharyngeal neoplasms, Human papilloma virus [more]
Organism: Human
Pathological State: Cancer
Mitoguardin 1 and 2 promote granulosa cell proliferation by activating AKT and regulating the Hippo-YAP1 signaling pathway
Cell Death & Disease (Nature) China, 27 November 2023
Reproductive Medicine
Key words: Cell proliferation, HIPPO signalling, Infertility, Mitochondria [more]
Organism: Mouse
Tissue: Ovaries
Low-dose radiotherapy combined with dual PD-L1 and VEGFA blockade elicits antitumor response in hepatocellular carcinoma mediated by activated intratumoral CD8+ exhausted-like T cells
Nature Communications (Nature) China, 24 November 2023
Oncology, Radiotherapy
Key words: Cancer therapy, Hepatocellular carcinoma, Radiotherapy, Tumour immunology [more]
Organism: Mouse
Tissue: Liver
Pathological State: Cancer
Acute expression of human APOBEC3B in mice results in RNA editing and lethality
Genome Biology (Springer) Germany, USA, Israel, 24 November 2023
Genetics
Key words: APOBEC3B, RNA editing, Mutations, Mouse models, DNA damage [more]
Organism: Mouse
Tissue: Liver, Pancreas, Intestine, Lung, Spleen
Expansion of CD4+ cytotoxic T lymphocytes with specific gene expression patterns may contribute to suppression of tumor immunity in oral squamous cell carcinoma: single-cell analysis and in vitro experiments
Frontiers in Immunology (Frontiers Media S.A.) Japan, UK, 23 November 2023
Immunology, Oncology
Key words: oral squamous cell carcinoma, CD4+ cytotoxic T lymphocytes, CTLA-4, T cell dysfunction, CXCL13, double negative B cells [more]
Organism: Human
Tissue: Tongue
Pathological State: Cancer
Improved cardioprotective effect of 3‐nitro‐N‐methyl salicylamide solution after a prolonged preservation time of rat heart
Clinical and Experimental Pharmacology and Physiology (Wiley) China, 23 November 2023
Cardiology
Organism: Rat
Tissue: Heart
Pathological State: Myocardial injury
Qi Fu Yin ameliorates neuroinflammation through inhibiting RAGE and TLR4/NF-κB pathway in AD model rats
Aging (Albany NY) (Impact Journals) China, 22 November 2023
Neurology, Pharmacology
Key words: Alzheimer’s disease, traditional Chinese medicine, neuroinflammation, RAGE, TLR4/NF-κB signaling pathway [more]
Organism: Rat
Tissue: Brain
Pathological State: Neuroinflammation
Identification of tryptophan metabolism-related genes in immunity and immunotherapy in Alzheimer's disease
Aging (Albany NY) (Impact Journals) China, 20 November 2023
Immunology, Neurology
Key words: Alzheimer’s disease, tryptophan metabolism-related genes, DEGs, WGCNA, bioinformatics [more]
Organism: Mouse
Tissue: Brain
Pathological State: Alzheimer’s disease
ALDOB/KAT2A interactions epigenetically modulate TGF-β expression and T cell functions in hepatocellular carcinogenesis
Hepatology (AASLD) China, 20 November 2023
Hepathology, Oncology
Pharmacological effects and mechanism of Maxing Shigan decoction in the treatment of Pseudomonas aeruginosa pneumonia
Journal of Ethnopharmacology (Elsevier) China, 19 November 2023
Pharmacology
Organism: Mouse
Tissue: Lung
Pathological State: Pseudomonas aeruginosa pneumonia
Vasari-Based Features Nomogram to Predict the Tumor-Infiltrating CD8+ T Cell Levels in Glioblastoma
Academic Radiology (Elsevier) China, 18 November 2023
Radiotherapy, Oncology
Chronic chromosome instability induced by Plk1 results in immune suppression in breast cancer
Cell Reports (Cell Press) Germany, 17 November 2023
Oncology
Key words: CP: Cancer; CP: Cell biology; Her2(+) breast cancer; NF-κβ signaling; chromosomal instability; immune evasion; senescence-associated secretory phenotype, SASP; single-cell sequencing. [more]
Organism: Mouse
Tissue: Breast
Pathological State: Cancer
Exploring CD39 and CD73 Expression as Potential Biomarkers in Prostate Cancer
Pharmaceuticals (MDPI) Brazil, 16 November 2023
Oncology
Key words: prostate cancer; ectonucleotidases; CD39; CD73; extracellular vesicles [more]
Organism: Human
Tissue: Prostate
Pathological State: Cancer
Structural, electrochemical, biological, and mechanical assessment of functionally graded Cr-based multilayers for enhanced metal-ceramic bond strength in dental restorations
Materials Chemistry and Physics (Elsevier) Romania, UK, Belgium, Russia, 15 November 2023
Biomaterials
Key words: Oxynitride, Cathodic arc, EIS, Cytotoxicity, Bond strength [more]
Cell Line: Human gingival fibroblasts
Impact of the-1T> C single-nucleotide polymorphism of the CD40 gene on the development of endothelial dysfunction in a pro-diabetic microenvironment
Atherosclerosis (Elsevier) Germany, The Netherlands, 14 November 2023
Endocrinology
Key words: Single nucleotide polymorphism, CD40, Endothelial cells, Endothelial-to-mesenchymal transition [more]
Pathological State: Type 2 diabetes and type 1 diabetes
Cell Line: Human endothelial cells
Gut microbiota regulates postprandial GLP-1 response via ileal bile acid-TGR5 signaling
Gut Microbes (Taylor & Francis) China, 09 November 2023
Gastroenterology
Key words: Microbiome, GLP-1, bile acid, TGR5, ileum, diabetes [more]
Organism: Mouse
Tissue: Small Intestine
Pathological State: Induced Intestinal Fibrosis
Toll-like receptor 9-positive plasmacytoid dendritic cells promote Th17 immune responses in oral lichen planus stimulated by epithelium-derived cathepsin K
Scientific reports (Nature) Japan, Bangladesh, 07 November 2023
Immunology, Dermatology
Key words: Inflammation, Innate immunity, Lymphocytes, Mucosal immunology [more]
Organism: Human
Tissue: Mucosa
Pathological State: Oral Lichen Planus (OLP) and hyperkeratosis
Use of Atrial Fibrillation Electrograms and T1/T2 Magnetic Resonance Imaging to Define the Progressive Nature of Molecular and Structural Remodeling–A New Paradigm Underlying the Emergence of Persistent Atrial Fibrillation
Journal of the American Heart Association (AHA) USA, 06 November 2023
Cardiology
Key words: Atrial Fibrillation, Electrophysiology, Fibrosis, Magnetic Resonance Imaging (MRI), Oxidant Stress [more]
Organism: Dog
Tissue: Heart
Pathological State: Atrial Fibrillation
Heterogeneity of Phase II Enzyme Ligands on Controlling the Progression of Human Gastric Cancer Organoids as Stem Cell Therapy Model
International Journal of Molecular Sciences (MDPI) Taiwan, 02 November 2023
Oncology, Stem Cell Research
Key words: cinnamaldehyde; gastric cancer development; organoids; perillaldehyde; reactive oxygen species [more]
Organism: Human
Tissue: Organoid
Pathological State: Cancer
A novel lncRNA GM15416 regulates osteoblast apoptosis and differentiation through the c-Fos/Fas axis and mitigates osteoporosis
International Journal of Biological Macromolecules (Elsevier) China, 02 November 2023
Osteology
Key words: lncRNA GM15416, C-Fos, Osteoporosis [more]
Organism: Mouse
Tissue: Bone
Pathological State: osteoporosis
Topical application of synthetic melanin promotes tissue repair
NPJ Regenerative Medicine (Nature) USA, 02 November 2023
Dermatology, Biomedical Engineering
Key words: Biomaterials, Cell death and immune response, Trauma [more]
Organism: Mouse
Tissue: Skin
Pathological State: Acute skin injury
Group 3 innate lymphoid cells exacerbate lupus nephritis by promoting B cell activation in kidney ectopic lymphoid structures
Advanced Science (Wiley) China, 01 November 2023
Nephrology
Organism: Human
Tissue: Kidney
Pathological State: Lupus nephritis
Cholesterol mediated ferroptosis suppression reveals essential roles of Coenzyme Q and squalene
Communications Biology (Nature) China, 01 November 2023
Metabolism
Key words: Lipid peroxides, Sterols [more]
Organism: Mouse
Tissue: Liver
CD24hiCD27+ Bregs within metastatic lymph nodes promote multi-drug resistance in breast cancer
Clinical Cancer Research (AACR) China, 31 October 2023
Oncology, Pharmacology
Organism: Mouse
Tissue: Xenograft Tumor, Heart, Liver, Spleen, Lung, Kidney
Pathological State: Cancer
Estrogen-related genes for thyroid cancer prognosis, immune infiltration, staging, and drug sensitivity
BMC Cancer (BMC) China, 31 October 2023
Oncology
Key words: Estrogen-related genes, Estrogen-related differential expressed genes, Progression-free interval, Thyroid cancer, Immune infiltration, Clinical relevance, Drug sensitivity [more]
Organism: Human
Tissue: Thyroid
Pathological State: Cancer
EXOSC5 maintains cancer stem cell activity in endometrial cancer by regulating the NTN4/integrin β1 signalling axis
International Journal of Biological Sciences (Ivy SPring) Taiwan, 31 October 2023
Oncology, Stem Cell Research
Key words: Endometrial carcinoma, cancer stem cells, c-MYC, EXOSC5, NTN4, integrin β1 [more]
Organism: Human
Tissue: Endometrium
Pathological State: Cancer
Antigen-caged-adjuvant nanovaccines elicit potent humoral and cellular immune responses
Nano Today (Elsevier) China, 31 October 2023
Immunology, Nanotechnology
Cell Line: murine DC2.4 cells and B16-F10 melanoma cells
Tumor-infiltrating platelets promote the growth of lung adenocarcinoma
Translational Oncology (Elsevier) China, 27 October 2023
Oncology
Key words: NSCLC, Lung adenocarcinoma, Tumor-infiltrating platelets, Fibrinogen, Coagulation [more]
Organism: Human
Tissue: Lung
Pathological State: Cancer
Acidosis promotes the metastatic colonization of lung cancer via remodeling of the extracellular matrix and vasculogenic mimicry
International Journal of Oncology (Spandios Publications) Taiwan, 26 October 2023
Oncology
Organism: Human
Tissue: Lung
Pathological State: Cancer
Dual antibody-aided mesoporous nanoreactor for H2O2 self-supplying chemodynamic therapy and checkpoint blockade immunotherapy in triple-negative breast cancer
Journal of Nanobiotechnology (Springer) Taiwan, 24 October 2023
Oncology, Pharmacology
Key words: Triple-negative Breast cancer (TNBC), Mesoporous nanoreactors, Chemodynamic therapy (CDT), Checkpoint blockade immunotherapy, Collaborative treatment [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Delineating spatial cell-cell interactions in the solid tumour microenvironment through the lens of highly multiplexed imaging
Frontiers in Immunology (Frontiers Media S.A.) Canada, USA, 23 October 2023
Oncology, Bioimaging
Key words: tumor immune microenvironment (TIME), tumor microenvironment (TME), tumor-infiltrating lymphocytes, immune checkpoint blockade, non-cell autonomous interactions, multiplexed imaging
Proteomic profiling of advanced melanoma patients to predict therapeutic response to anti-PD-1 therapy
Clinical Cancer Research (AACR) Austria, Switzerland, Germany, 20 October 2023
Oncology, Pharmacology
Key words: Predictive biomarker, Immunotherapy, Serum depletion, Glycoproteomics, SWATH/DIA mass spectrometry [more]
Organism: Human
Tissue: Skin
Pathological State: Cancer
Cerebral organoids derived from patients with Alzheimer's disease with PSEN1/2 mutations have defective tissue patterning and altered development
Cell Reports (Cell Press) Czech Republic, 20 October 2023
Neuroscience
Organism: Human
Tissue: Organoid
Pathological State: Alzheimer’s disease
TRIM69 suppressed the anoikis resistance and metastasis of gastric cancer through ubiquitin‒proteasome-mediated degradation of PRKCD
Oncogene (Nature) China, 20 October 2023
Oncology
Key words: Apoptosis, Extracellular matrix, Gastric cancer, Ubiquitylation [more]
Organism: Human
Tissue: Stomach
Pathological State: Cancer
Extracellular vesicles of the probiotic bacteria E. coli O83 activate innate immunity and prevent allergy in mice
Cell Communication and Signaling (Springer) Austria, Poland, Czech Republic, Denmark, 20 October 2023
Immunology
Key words: Allergic airway inflammation, Extracellular vesicles, Outer membrane vesicles, Microbiota and innate immunity, Nasal route of administration [more]
Organism: Mouse
Tissue: Lung
Pathological State: E. coli O83 Infection
Omentin-1 ameliorates the progress of osteoarthritis by promoting IL-4-dependent anti-inflammatory responses and M2 macrophage polarization
International Journal of Biological Sciences (Ivyspring International Publisher) Taiwan, 18 October 2023
Osteology, Immunology
Key words: Omentin-1, Osteoarthritis, IL-4, M2 macrophage, Anti-inflammation [more]
Organism: Human, Rat
Tissue: Synovium
Pathological State: Osteoarthritis
Effect of the Functional VP1 Unique Region of Human Parvovirus B19 in Causing Skin Fibrosis of Systemic Sclerosis
International Journal of Molecular Sciences (MDPI) Taiwan, 18 October 2023
Dermatology
Key words: human parvovirus B19 (B19), systemic sclerosis (SSc), VP1 unique region (VP1u), macrophages, fibrosis [more]
Organism: Human
Tissue: Skin
Pathological State: Human Parvovirus B19 induced Skin Fibrosis
Single-cell RNA sequencing reveals pro-invasive cancer-associated fibroblasts in hypopharyngeal squamous cell carcinoma
Cell Communication and Signaling (Springer) China, 18 October 2023
Oncology
Key words: Single-cell RNA sequencing, Hypopharyngeal squamous cell carcinoma, Tumor microenvironment, Extracellular matrix cancer-associated fibroblast, Precision therapy [more]
Organism: Human
Tissue: Pharynx
Pathological State: Cancer
Chromogenic detection of telomere lengths in situ aids the identification of precancerous lesions in the prostate
The Prostate (Wiley) USA, 17 October 2023
Oncology
Key words: chromogenic, diagnostic, in situ hybridization, prostate cancer, telomeres [more]
Organism: Human
Tissue: Prostate
Pathological State: Cancer
Danggui Shaoyao San ameliorates the lipid metabolism via the PPAR signaling pathway in a Danio rerio (zebrafish) model of hyperlipidemia
Biomedicine & Pharmacotherapy (Elsevier) China, 16 October 2023
Endocrinology
Key words: Danggui Shaoyao San, Hyperlipidemia, PPAR signaling pathway, Danio rerio, Lipid metabolism [more]
Organism: Zebrafish
Tissue: Liver
Pathological State: Hyperlipidemia
Hypoxic microenvironment determines the phenotypic plasticity and spatial distribution of cancer‐associated fibroblasts
Clinical and Translational Medicine (ncbi.nlm.nih.gov) South Korea, 14 October 2023
Oncology
Organism: Human
Tissue: Pancreas
Pathological State: Cancer
Kindlin-2 in myoepithelium controls luminal progenitor commitment to alveoli in mouse mammary gland
Cell Death & Disease (Nature) China, 13 October 2023
Reproductive Medicine
Key words: Cell signalling, Differentiation [more]
Organism: Mouse
Tissue: Breast
A marmoset brain cell census reveals regional specialization of cellular identities
Science Advances (Science) USA, Italy, 12 October 2023
Neuroscience, Zoology
Organism: Marmoset
Tissue: Brain
A molecular landscape of quiescence and proliferation highlights the role of Pten in mammary gland acinogenesis
Journal of Cell Science (The Company of Biologists) Brazil, 11 October 2023
Cell Biology
Key words: Pten, Basement membrane, Cell cycle, Extracellular matrix, Mammary gland acinogenesis, Quiescence [more]
Organism: Mouse
Tissue: Breast
Cell Line: EpH4 cells
Donor bone marrow–derived macrophage engraftment into the central nervous system of patients following allogeneic transplantion
Blood Advances (ASH Publications) USA, 10 October 2023
Hematology
Key words: Immunobiology and Immunotherapy, Transplantation [more]
Organism: Human
Tissue: Brain
Pathological State: Hematopoietic stem cell transplantation
Novel ratio-expressions of genes enables estimation of wound age in contused skeletal muscle
International Journal of Legal Medicine (Springer) China, 07 October 2023
Osteology
Key words: Ratio-expressions of genes, Real-time PCR, Wound age estimation, Skeletal muscle [more]
Organism: Rat
Tissue: Muscle
Bladder cancer intrinsic LRFN2 drives anticancer immunotherapy resistance by attenuating CD8+ T cell infiltration and functional transition
Journal for ImmunoTherapy of Cancer (BMJ Journals) China, 06 October 2023
Oncology
Organism: Human
Tissue: Bladder
Pathological State: Cancer
Local reference values for tissue characterization by cardiac magnetic resonanceimaging. Myocardial mapping using parametric sequences
Revista de la Federación Argentina de Cardiología (Federación Argentina de Cardiología) Argentina, 06 October 2023
Cardiology
Key words: Tissue Characterization,T1 Mapping, T2 Mapping,extracellular volume
Acrylamide, an Air Pollutant, Enhances Allergen-Induced Eosinophilic Lung Inflammation via Group 2 Innate Lymphoid Cells
Mucosal Immunology (Elsevier) Taiwan, 05 October 2023
Allergy Research
Key words: Acrylamide, Air pollutant, Asthma, Eosinophilic Inflammation, Group 2 innate lymphoid cell [more]
Organism: Mouse
Tissue: Lung
Pathological State: Asthma
Development of an image processing software for quantification of histological calcification staining images
PloS one (PLOS) China, 05 October 2023
Medical Image Analysis
Key words: Alizarin staining, Histology, Imaging techniques, Calcification, Cell staining, Hematoxylin staining, Staining Stem cells
A comprehensive strategy to strengthen bioimaging in Africa though the Africa Microscopy Initiative
Nature Cell Biology (Nature) South Africa, 05 October 2023
Key words: Imaging, Microscopy
The RBPMSCreERT2-tdTomato mouse line for study retinal and vascular relevant diseases
Iscience (Cell Press) China, 02 October 2023
Biological Methods
Organism: Mouse
Tissue: Embryo, Eye
The RBPMSCreERT2-tdTomato mouse line for studying retinal and vascular relevant diseases
Iscience (Cell Press) China, 02 October 2023
Biological Methods
Key words: Natural sciences, Biological sciences, Physiology, Biological sciences research methodologies [more]
Organism: Mouse
Tissue: Eye
Donor bone marrow–derived macrophage engraftment into the central nervous system of patients following allogeneic transplantation
Blood Advances (ASH Publications) USA, 29 September 2023
Transplantation Science
Key words: Immunobiology and Immunotherapy, Transplantation [more]
Organism: Human
Tissue: Brain
Activation of the p62-Keap1-Nrf2 pathway protects against oxidative stress and excessive autophagy in ovarian granulosa cells to attenuate DEHP-induced ovarian impairment in mice
Ecotoxicology and Environmental Safety (Elsevier) China, 28 September 2023
Toxicology, Reproductive Medicine
Key words: Di-(2-ethylhexyl) phthalate, Female reproductive toxicity, Ovarian granulosa cells, Excessive autophagy, Oxidative stress, P62-Keap1-Nrf2 pathway [more]
Organism: Mouse
Tissue: Ovaries
Metformin inhibits inflammatory response and endoplasmic reticulum stress to improve hypothalamic aging in obese mice
Iscience (Elsevier) China, 27 September 2023
Endocrinology
Key words: Physiology, Molecular biology, Neuroscience, Immunology [more]
Organism: Mouse
Tissue: Brain
Pathological State: Obesity
A comparative analysis of microglial inducible Cre lines
Cell Reports (Cell Press) USA, Germany, Japan, 26 September 2023
Neuroscience
Key words: Microglia, Cre/LoxP, CreER, recombination [more]
Organism: Mouse
Tissue: Brain
ROCK inhibition reduces the sensitivity of mutant p53 glioblastoma to genotoxic stress through a Rac1-driven ROS production
The International Journal of Biochemistry & Cell Biology (Elsevier) Austria, 23 September 2023
Immunology, SARS-CoV-2
Key words: Neutrophil Extracellular Traps, Oxidative Stress, Post-Acute COVID-19 Syndrome, Thromboinflammation, Thrombosis [more]
Cell Line: GBM cell lines U87-MG (wild type p53) and T98G (mutant p53)
STAT3-EphA7 axis contributes to the progression of esophageal squamous cell carcinoma
Acta Oncologica (Taylor & Francis) China, 22 September 2023
Oncology
Key words: STAT3, EphA7, transcription, ESCC, promoter [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Dominant-negative HNF1α mutant promotes liver steatosis and inflammation by regulating hepatic complement factor D
iScience (Cell Press) China, 22 September 2023
Hepathology
Effect of different sperm populations on neutrophils extracellular traps (NETs) formation in cattle
Research in Veterinary Science (Elsevier) Chile, Germany, 22 September 2023
Zoology, Reproductive Medicine
Key words: Bovine, Spermatozoa, Neutrophil extracellular traps, Sperm motility [more]
Organism: Cow
Cell Line: Sperm
Optimising multiplex immunofluorescence staining for characterising the tumour immune micro-environment
Methods (Elsevier) Australia, 21 September 2023
Microscopy
Key words: Colorectal cancer, Multiplex immunofluorescence, Automated staining, Tumor immune microenvironment [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Platinum-Based Twin Drug Modulates Tumor-Infiltrating Immune Cells to Improve Immune Checkpoint Blockade Therapy
Journal of Medicinal Chemistry (ACS Publications) China, 20 September 2023
Oncology, Immunology
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
The intratumor mycobiome promotes lung cancer progression via myeloid-derived suppressor cells
Cancer Cell (Cell Press) China, France, 19 September 2023
Oncology
Key words: Aspergillus, CARD9, IL-1β, β-glucan, Intratumor mycobiome, Lung adenocarcinoma, Myeloid-Derived Suppressor Cells. [more]
Organism: Mouse
Tissue: Lung, Allograft Tumor
Pathological State: Cancer
Propolis as a Potential Therapeutic Agent to Counteract Age-Related Changes in Cartilage: An In Vivo Study
International Journal of Molecular Sciences (MDPI) Chile, 19 September 2023
Rheumatology
Key words: Osteoarthritis, Propolis, Aging [more]
Organism: Rat
Tissue: Joint Tissue
Impact of Perinatal Coexposure to Chlorpyrifos and a High-Fat Diet on Kisspeptin and GnRHR Presence and Reproductive Organs
Toxics (MDPI) France, Tunisia, 19 September 2023
Reproductive Medicine, Endocrinology
Key words: chlorpyrifos, high-fat diet, Kisspeptin, GnRHR, ovary, testis, rat [more]
Organism: Rat
Tissue: Ovaries, Testis
Postirradiation temperature influences DSB repair and dicentric chromosome formation—potential impact for dicentric chromosome analysis in interlaboratory comparisons
Radiation Protection Dosimetry (Oxford Academic) Germany, 18 September 2023
Radiotherapy
Cell Line: Human peripheral blood mononuclear cells (PBMCs)
RNA‐binding protein‐regulated fibronectin is essential for EGFR‐activated metastasis of head and neck squamous cell carcinoma
The FASEB Journal (Wiley) Taiwan, 17 September 2023
Oncology
Key words: EGF, fibronectin, metastasis, RNA- binding protein [more]
Organism: Mouse
Tissue: Xenograft Tumor, Heart, Liver, Spleen, Lung, Kidney
Pathological State: Cancer
A molecular landscape of quiescence/proliferation highlights the role of Pten in mammary gland acinogenesis
Journal of Cell Science (The Company of Biologists) Brazil, 15 September 2023
Oncology
Key words: Pten, Basement membrane, Cell cycle, Extracellular matrix, Mammary gland acinogenesis, Quiescence [more]
Cell Line: EpH4 cells
Noncanonical CDK4 signaling rescues diabetes in a mouse model by promoting β cell differentiation
The Journal of Clinical Investigation (ncbi.nlm.nih.gov) USA, 15 September 2023
Endocrinology
Key words: Metabolism, Beta cells, Cell cycle, Insulin [more]
Organism: Mouse
Tissue: Pancreas
Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis
Cell (Cell Press) USA, Japan, UK, Germany, 14 September 2023
Hematology
Key words: JAK-STAT, TpoR, c-MPL, cryo-EM, hematopoiesis, ligand engineering, mTOR, signaling, structure, thrombopoietin [more]
Organism: Mouse
Tissue: Bone Marrow
Community-developed checklists for publishing images and image analyses
Nature Methods (Nature) Italy, USA, Germany, the Netherlands, Chile, Portugal, Australia, Austria, Sweden, Spain, UK, France, Canada, China, Saudi Arabia, Switzerland, 14 September 2023
Microscopy
Key words: Microscopy, Publishing
Breaking through the basement membrane barrier to improve nanotherapeutic delivery to tumours
Nature Nanotechnology (Nature) China, Singapore, 14 September 2023
Nanomedicine, Oncology
Key words: Drug delivery, Nanoparticles, Nanotechnology in cancer [more]
Organism: Mouse
Tissue: Xenograft Tumor, Heart, Liver, Spleen, Lung, Kidney
Pathological State: Cancer
The combination of quercetin and leucine synergistically improves grip strength by attenuating muscle atrophy by multiple mechanisms in mice exposed to cisplatin
Plos one (PLOS) Taiwan, 12 September 2023
Myology
Key words: Leucine, Muscle tissue, Muscle proteins, Gastrocnemius muscles, Glycogens, Skeletal muscles, Muscle protein synthesis, Cancer treatment [more]
Organism: Mouse
Tissue: Muscle
Construction and validation of cervical cancer prognostic model based on tumor immune cycle-related genes
Chinese Journal of Oncology Prevention and Treatment (manu33.magtech.com.cn) China, 12 September 2023
Oncology
Key words: Cervical cancer, Prognostic model, Tumor immune cycle related genes, Multi?color , fluorescence immunohistochemistry
Aralia saponin A isolated from Achyranthes bidentata Bl. ameliorates LPS/D-GalN induced acute liver injury via SPHK1/S1P/S1PR1 pathway in vivo and in vitro
International Immunopharmacology (Elsevier) China, 11 September 2023
Immunology, Pharmacology
Key words: Acute liver injury, Aralia saponin A, Transcriptomics, Metabonomics, SPHK1/S1P/S1PR1 pathway [more]
Organism: Mouse
Tissue: Liver
Pathological State: Acute liver injury
Fibroblast growth factor 5 expression predicts the progression of oral squamous cell carcinoma
Journal of the Formosan Medical Association (Elsevier) Taiwan, 11 September 2023
Oncology
Key words: Fibroblast growth factor 5, Oral cancer, Progression, Risk factors, Survival [more]
Organism: Mouse
Tissue: Xenograft Tumor, Heart, Liver, Spleen, Lung, Kidney
Pathological State: Cancer
FUNDC2, a mitochondrial outer membrane protein, mediates triple-negative breast cancer progression via the AKT/GSK3β/GLI1 pathway
Acta Biochimica et Biophysica Sinica (Oxford University Press) China, 11 September 2023
Oncology
Key words: FUNDC2, GLI1, triple-negative breast cancer (TNBC), therapeutic target [more]
Organism: Human
Tissue: Breast
Pathological State: Cancer
Technological Innovations and the Advancement of Preventive Healthcare for Society 5.0
Society 5.0 and Next Generation Healthcare (Springer) South Africa, Austria, Australia, 10 September 2023
Key words: Preventive medicine, Healthcare, Therapeutic healthcare, Diagnostic healthcare, Low- and middle-income countries, SDGs, Energy crisis, Human rights, Data ownership
Thymopentin ameliorates experimental colitis via inhibiting neutrophil extracellular traps
International Immunopharmacology (Elsevier) China, 09 September 2023
Immunology, Gastroenterology
Key words: Crohn's disease, Thymopentin, Neutrophil extracellular traps, Colitis, Neoseptin 3 [more]
Organism: Mouse
Tissue: Colon
Pathological State: Colitis
Innate Mechanism of Mucosal Barrier Erosion in the Pathogenesis of Acquired Colitis
iScience (Cell Press) USA, South Korea, Germany, 09 September 2023
Gastroenterology, Immunology
Key words: Biochemistry, Molecular biology, Immunology, Microbiology [more]
Organism: Mouse
Tissue: Small Intestine
Pathological State: Colitis
Mitochondrial impairment and synaptic dysfunction are associated with neurological defects in iPSCs-derived cortical neurons of MERRF patients
Journal of Biomedical Science (Springer) Taiwan, 09 September 2023
Neuroscience
Key words: AMPARs, Disease modeling, Electrophysiological activity, Excitatory neurons, iPSCs, MERRF syndrome, mtDNA mutation, Neurological defect, Synaptic plasticity, Synaptophysin [more]
Cell Line: human iPSCs
Formin protein FMNL1 is a biomarker for tumor-infiltrating immune cells and associated with well immunotherapeutic response
Journal of Cancer (Ivyspring International Publisher) China, 09 September 2023
Oncology
Key words: FMNL1, bioinformatics, biomarker, cancer, mQIF [more]
Organism: Human
Tissue: Liver
Pathological State: Cancer
Neutrophil extracellular traps are involved in the occurrence of interstitial lung disease in a murine experimental autoimmune myositis model
Clinical and Experimental Immunology (Oxford Academic) China, 08 September 2023
Immunology
Key words: idiopathic inflammatory myopathy (IIMs), experimental autoimmune myositis (EAM), interstitial lung disease (ILD), neutrophil extracellular traps (NETs) [more]
Organism: Mouse
Tissue: Lung
Pathological State: Interstitial Lung Disease
A Specific Mini‐Intrabody Mediates Lysosome Degradation of Mutant Huntingtin
Advanced Science (Wiley) China, 08 September 2023
Neuroscience, Cell Biology
Key words: HD KI-140Q mice, intravenous injection, lysosome, mini-intrabody, mu-tant huntingtin, SM3, stereotaxic injection [more]
Organism: Mouse
Tissue: Brain
Pathological State: Huntington's disease
Genomic and Phenotypic Biomarkers for Precision Medicine Guidance in Advanced Prostate Cancer
Current Treatment Options in Oncology (Springer) Australia, Iran, Austria, 08 September 2023
Oncology
Key words: Advanced prostate cancer, Genotypic biomarkers, Phenotypic biomarkers, Precision medicine
Metabolic intervention by low carbohydrate diet suppresses the onset and progression of neuroendocrine tumors
Cell Death & Disease (Nature) Japan, 07 September 2023
Oncology, Endocrinology
Key words: Cancer models, Neuroendocrine cancer [more]
Organism: Mouse
Tissue: Pancreas
Pathological State: Cancer
Persister cell phenotypes contribute to poor patient outcomes after neoadjuvant chemotherapy in PDAC
Nature Cancer (Nature) Germany, Japan, Austria, UK, Portugal, 07 September 2023
Oncology
Key words: Cancer, Pancreatic cancer, Tumour biomarkers [more]
Organism: Human
Tissue: Pancreas, Spheroid
Pathological State: Cancer
Correlation of tumor-associated macrophage infiltration in glioblastoma with magnetic resonance imaging characteristics: a retrospective cross-sectional study
Quantitative Imaging in Medicine and Surgery (AME Publishing Company) China, 07 September 2023
Oncology, Microscopy
Key words: Glioblastoma (Gb), tumor-associated macrophage (TAM), magnetic resonance imaging (MRI), tumor microenvironment [more]
Organism: Human
Tissue: Brain
Pathological State: Cancer
Genomic and Transcriptomic Landscape of an Oral Squamous Cell Carcinoma Mouse Model for Immunotherapy
Cancer Immunology Research (AACR) Taiwan, 05 September 2023
Oncology, Immunology
Organism: Mouse
Tissue: Tongue
Pathological State: Cancer
PTBP1 plays an important role in the development of gastric cancer
Cancer Cell International (BMC) China, Japan, 05 September 2023
Oncology
Key words: PTBP1:Polypyrimidine Tract binding protein 1, Gastric cancer, Proliferation, Actin cytoskeleton remodeling, PTBP1 Cas9-KO mouse model [more]
Organism: Human
Tissue: Stomach
Pathological State: Cancer
Oleic acid-induced metastasis of KRAS/p53-mutant colorectal cancer relies on concurrent KRAS activation and IL-8 expression bypassing EGFR activation
Theranostics (Ivyspring International Publisher) Taiwan, 05 September 2023
Oncology
Key words: multigene mutant CRC, oleic acid, IL-8, KRAS activation, metastasis [more]
Organism: Mouse
Tissue: Lung
Pathological State: Cancer
NETs induce persistent lung tissue damage via thromboinflammation without altering virus resolution in a mouse coronavirus model
Journal of Thrombosis and Haemostasis (Elsevier) Austria, 04 September 2023
Pulmonology, Immunology, SARS-CoV-2
Key words: Neutrophil Extracellular Traps, Oxidative Stress, Post-Acute COVID-19 Syndrome, Thromboinflammation, Thrombosis
SUMO1-regulated DBC1 promotes p53-dependent stress-induced apoptosis of lens epithelial cells
Aging (Impact Journals) China, 04 September 2023
Ophthalmology
Key words: lens, cataract, apoptosis, DBC1, p53, oxidative stress [more]
Cell Line: Mouse lens epithelial cell line (αTN4-1) and Human lens epithelial cell line (HLE and FHL124)
The combination of NDUFS1 with CD4+ T cell infiltration predicts favorable prognosis in kidney renal clear cell carcinoma
Frontiers in Cell and Developmental Biology (Frontiers Media S.A.) China, 04 September 2023
Nephrology
Key words: kidney renal clear cell carcinoma, NDUFS1, survival, hsa-miR-320b, CD4+ T cell infiltration [more]
Organism: Human
Tissue: Kidney
Pathological State: Cancer
Platinum Twin and Triplet Drugs Improve Chemoimmunotherapy
Journal of Medicinal Chemistry (ACS Publications) China, USA, 04 September 2023
Oncology, Pharmacology
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Generation of inactivated IL2RG and RAG1 monkeys with severe combined immunodeficiency using base editing
Signal Transduction and Targeted Therapy (Nature) China, 04 September 2023
Genetics
Key words: Experimental models of disease, Genetic engineering [more]
Organism: Monkey
Tissue: Breast
Pathological State: Cancer
Anti-tumor effects of deubiquitinating enzyme inhibitor PR-619 in human chondrosarcoma through reduced cell proliferation and endoplasmic reticulum stress-related apoptosis
American Journal of Cancer Research (e-Century Publishing) Taiwan, 03 September 2023
Oncology
Key words: Deubiquitinating enzyme, chondrosarcoma, apoptosis, endoplasmic reticulum stress [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Mesenchymal stem cells promote polarization of M2 macrophages in mice with acute-on-chronic liver failure via Mertk/JAK1/STAT6 signaling
Stem Cells (Oxford Academic) China, 02 September 2023
Stem Cell Research, Hepathology
Key words: mesenchymal stem cell, acute-on-chronic liver failure, macrophage, polarization, Mertk, JAK1/STAT6 [more]
Organism: Mouse
Tissue: Liver
Pathological State: Liver failure
Plasmon-activated water as a therapeutic strategy in Alzheimer's disease by altering gut microbiota
Aging (Impact Journals) Taiwan, 02 September 2023
Neuroscience, Gastroenterology
Key words: Alzheimer’s disease, plasmon-activated water, fecal microbiota transplantation, microbiota, beta amyloid, tau [more]
Organism: Mouse
Tissue: Brain
Pathological State: Alzheimer’s disease
Impact of apolipoprotein A1 on tumor immune microenvironment, clinical prognosis and genomic landscape in hepatocellular carcinoma
Precision Clinical Medicine (Oxford Academic) China, The Netherlands, 02 September 2023
Oncology
Organism: Human
Tissue: Liver
Pathological State: Cancer
Escherichia coli adhesion portion FimH polarizes M2 macrophages to M1 macrophages in tumor microenvironment via toll-like receptor 4
Frontiers in Immunology (Frontiers Media S.A.) China, South Korea, 01 September 2023
Immunology
Key words: fimH, macrophage polarization, toll-like receptor 4, myeloid differentiation factor 2, tumor-associated macrophage [more]
Organism: Mouse
Tissue: Allograft Tumor
Pathological State: Cancer
Kunitz-type protease inhibitor TFPI2 remodels stemness and immunosuppressive tumor microenvironment in glioblastoma
Nature Immunology (Nature) USA, 31 August 2023
Oncology, Immunology
Key words: Cancer immunotherapy, Immunosurveillance, Stem cells, Tumour immunology [more]
Cell Line: HMC3 microglia, 293T cells, CT2A cells, SIM-A9 microglia, and SB28 and GL261 cells
Engineering tumoral vascular leakiness with gold nanoparticles
Nature Communications (Nature) Singapore, China, Japan, Australia, 30 August 2023
Oncology, Nanomedicine
Key words: Cancer, Nanoscale materials [more]
Organism: Mouse
Tissue: Xenograft Tumor, Heart, Liver, Spleen, Lung, Kidney
Pathological State: Cancer
The Cooperative Human Tissue Network of the National Cancer Institute: Supporting cancer research for 35 years
Molecular Cancer Therapeutics (AACR) USA, 30 August 2023
Oncology
FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth
Cell Reports (Cell Press) China, 29 August 2023
Oncology
Key words: CDK4, CP: Cancer, CP: Molecular biology, CRC, FRMD8, MDM2, RB. [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Synergy of 5-aminolevulinate supplement and CX3CR1 suppression promotes liver regeneration via elevated IGF-1 signaling
Cell Reports (Cell Press) China, 29 August 2023
Hepathology
Key words: 5-aminolevulinate, CP: Immunology, CP: Metabolism, CX3CR1, P53, hepatectomy, hepatocyte proliferation, insulin-like growth factor 1, liver regeneration, liver zonation, macrophage polarization, partial liver transplantation [more]
Organism: Mouse
Tissue: Liver
Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis
Cell Reports (Cell Press) China, 29 August 2023
Oncology, Immunology
Key words: IFN-β signaling, T cell exhaustion, TCF19, endometrial cancer, immune checkpoint blockade therapy, microsatellite instable [more]
Organism: Human
Tissue: Endometrium
Pathological State: Cancer
Single-cell transcriptomics reveals granzyme K–expressing cytotoxic Tfh cells in tertiary lymphoid structures in IgG4-RD
Journal of Allergy and Clinical Immunology (Elsevier) Japan, 29 August 2023
Immunology
Key words: Single-cell RNA sequencing, IgG4-related disease, germinal center, granzyme K, T follicular helper cells, T follicular regulatory cells [more]
Organism: Human
Tissue: Submandibular Gland, Lymphoid Tissue, Kidney
Pathological State: IgG4-related disease
The rs1421085 variant within FTO promotes brown fat thermogenesis
Nature Metabolism (Nature) China, USA, 29 August 2023
Endocrinology
Key words: Fat metabolism, Genome-wide association studies, Mechanisms of disease [more]
Organism: Human
Tissue: Adipose Tissue
Mitochondrial integrated stress response controls lung epithelial cell fate
Nature (Nature) USA, South Korea, Spain, 28 August 2023
Pulmonology
Key words: Differentiation, Metabolomics [more]
Organism: Mouse
Tissue: Lung
Blocking Tim-3 enhances the anti-tumor immunity of STING agonist ADU-S100 by unleashing CD4+ T cells through regulating type 2 conventional dendritic cells
Theranostics (Ivyspring International Publisher) China, 25 August 2023
Oncology, Immunology
Key words: STING, ADU-S100, Tim-3, DC, Cancer immunotherapy [more]
Organism: Human
Tissue: Lung
Pathological State: Cancer
Anti-angiogenic therapy using the multi-tyrosine kinase inhibitor Regorafenib enhances tumor progression in a transgenic mouse model of ß-cell carcinogenesis
British Journal of Cancer (Nature) Germany, Austria, 24 August 2023
Oncology
Key words: Pancreatic cancer, Target validation, Tumour angiogenesis [more]
Organism: Mouse
Tissue: Placenta
Pathological State: Cancer
Clinical-mediated discovery of pyroptosis in CD8+ T cell and NK cell reveals melanoma heterogeneity by single-cell and bulk sequence
Cell Death & Disease (Nature) China, 24 August 2023
Oncology
Key words: Melanoma, Prognostic markers [more]
Organism: Human
Tissue: Skin
Pathological State: Cancer
PNU-74654 Induces Cell Cycle Arrest and Inhibits EMT Progression in Pancreatic Cancer
Medicina (MDPI) Taiwan, 24 August 2023
Oncology, Pharmacology
Key words: pancreatic adenocarcinoma, β-catenin, WNT, cell cycle arrest, migration [more]
Cell Line: BxPC-3 and MiaPaCa-2 cell lines
Repression of rRNA gene transcription by endothelial SPEN deficiency normalizes tumor vasculature via nucleolar stress
The Journal of Clinical Investigation (Am Soc Clin Investig) China, 22 August 2023
Oncology
Key words: SPEN, rDNA, nucleolar stress, pRNA, endothelial cells, tumor vessels [more]
Organism: Mouse
Tissue: Eye
Pathological State: Cancer
Chemotherapy-induced nanovaccines implement immunogenicity equivalence for improving cancer chemoimmunotherapy
Biomaterials (Elsevier) China, USA, 21 August 2023
Oncology, Pharmacology
Key words: Chemoimmunotherapy, Nanovaccines, Neoantigens, Damage associated molecular patterns, Anti-PD-1 [more]
Organism: Mouse
Tissue: Heart, Liver, Spleen, Lung, Kidney
Pathological State: Cancer
Integrative Evaluation of the Clinical Significance Underlying Protein Arginine Methyltransferases in Hepatocellular Carcinoma
Cancers (MDPI) China, South Korea, 20 August 2023
Oncology
Key words: protein arginine methyltransferase, protein methylation, hepatocellular carcinoma, T cell exhaustion, tissue microarray, prognostic marker [more]
Organism: Human
Tissue: Liver
Pathological State: Cancer
High G9a Expression in DLBCL and Its Inhibition by Niclosamide to Induce Autophagy as a Therapeutic Approach
Cancers (MDPI) Taiwan, USA, 17 August 2023
Oncology, Pharmacology
Key words: DLBCL, G9a/EHMT2, niclosamide, autophagy, immunohistochemistry, TissueFAXS PLUS, HistoQuest [more]
Organism: Human
Tissue: Lymphoid Tissue
Pathological State: Cancer
Alveolar Ridge Augmentation with a Novel Combination of 3D-Printed Scaffolds and Adipose-Derived Mesenchymal Stem Cells—A Pilot Study in Pigs
Biomedicines (MDPI) Singapore, USA, 16 August 2023
Tissue Engineering
Key words: alveolar ridge augmentation, 3D-printed scaffolds, adipose-derived mesenchymal stem cells, tissue engineering, pig model [more]
Organism: Pig
Cell Line: Scaffold
An Engineered Adeno-Associated Virus Capsid Mediates Efficient Transduction of Pericytes and Smooth Muscle Cells of the Brain Vasculature
Human Gene Therapy (Mary Ann) USA, 16 August 2023
Neuroscience, Pharmacology
Key words: adeno-associated virus vector, pericytes, smooth muscle cells [more]
Organism: Mouse
Tissue: Brain, Blood Vessels
The putative protein kinase Stk36 is essential for ciliogenesis and CSF flow by associating with Ulk4
The FASEB Journal (Wiley) China, Ireland, 16 August 2023
Neuroscience
Key words: ependymal cells, hydrocephalus, motile cilia, Stk36, Ulk4, ventriculomegaly [more]
Organism: Mouse
Tissue: Brain
Transcription factor Zhx2 is a checkpoint that programs macrophage polarization and antitumor response
Cell Death & Differentiation (Nature) China, 15 August 2023
Oncology, Immunology
Key words: Cancer microenvironment, Inflammation [more]
Organism: Human
Tissue: Liver
Pathological State: Cancer
Obstruction of the Tear Drainage Altered Lacrimal Gland Structure and Function
Investigative Opthalmology & Visual Science (iovs.arvojournals.org) China, 12 August 2023
Ophthalmology
Organism: Mouse
Tissue: Eye
STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway
Molecular Brain (BMC) Austria, USA, Switzerland, Czech Republic, Sweden, Spain, UK, Italy, France, 12 August 2023
Oncology
Key words: STAT3, mTORC1, AR, Prostate Cancer, LKB1, AMPK, CREB, Metformin [more]
Organism: Human
Tissue: Prostate
Pathological State: Cancer
Jdp2 is a spatiotemporal transcriptional activator of the AhR via the Nrf2 gene battery
Inflammation and Regeneration (BMC) Taiwan, Japan, 11 August 2023
Cell Biology
Key words: Antioxidation, Aryl hydrocarbon receptor, Dioxin responsive element, Nuclear factor (erythroid-derived 2)-like 2 transcription factor, Jun dimerization protein 2, Oxidative stress, Reactive oxygen species, Transcriptional regulation
FK506-Binding Protein Like (FKBPL) Regulates Hypoxia-induced Factor-α and Restores Endothelial Function and Vascular Integrity in Ischaemia-induced Angiogenesis
Heart, Lung and Circulation (Elsevier) Australia, Austria, 10 August 2023
Cardiology
Case report: genetic and immune microenvironmental characteristics of a rectal cancer patient with MSS/PD-L1-negative recurrent hepatopulmonary metastasis who achieved complete remission after treatment with PD-1 inhibitor
Frontiers in Immunology (Frontiers Media S.A.) China, 09 August 2023
Oncology, Pharmacology
Key words: MSS, rectal cancer, hepatopulmonary metastasis, immunotherapy, tumor immune microenvironment [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Compartmentalized Nano-MOFs as Co-delivery Systems for Enhanced Antitumor Therapy
ACS Applied Materials & Interfaces (ACS Publications) China, 08 August 2023
Oncology, Pharmacology
Key words: bioactive macromolecules compartmentalized structures nano-metal-organic frameworks co-delivery cancer therapy [more]
Organism: Mouse
Tissue: Xenograft Tumor, Liver, Kidney
Pathological State: Cancer
Unrepaired base excision repair intermediates in template DNA strands trigger replication fork collapse and PARP inhibitor sensitivity
The EMBO Journal (EMBO Press) UK, Brazil, Germany, 07 August 2023
Cell Biology
Key words: bioactive macromolecules, compartmentalized structures, nano-metal-organic frameworks, co-delivery, cancer therapy [more]
Cell Line: RPE-1, U2OS and SUM149 cells
Bj-PRO-10c, as an allosteric regulator of argininosuccinate synthase, is a potential therapy for neuroblastoma metastasis
Toxicon (Elsevier) Brazil, 06 August 2023
Oncology, Pharmacology
Key words: Metastasis, Nitric oxide, Proline-rich peptide, Neuroblastoma, Tumor progression [more]
Cell Line: SH-SY5Y cells
Unveiling nature's potential weapon: Magnolol's role in combating bladder cancer by upregulating the miR-124 and inactivating PKC-δ/ERK axis
Phytomedicine (Elsevier) Taiwan, 05 August 2023
Oncology, Pharmacology
Key words: Bladder cancer, ERK, Magnolol, miR-124-3p, NF-κB, PKCδ [more]
Organism: Mouse
Tissue: Kidney, Liver, Spleen, Small Intestine
Aberrant expression of IL-17A in mast cells contributes to the pathogenesis of hidradenitis suppurativa
British Journal of Dermatology (Oxford Academic) Taiwan, 04 August 2023
Dermatology
Organism: Human
Tissue: Skin
Pathological State: Hidradenitis suppurativa
The diapause-like colorectal cancer cells induced by SMC4 attenuation are characterized by low proliferation and chemotherapy insensitivity
Cell Metabolism (Cell Press) China, 04 August 2023
Oncology
Key words: diapause-like state, chemotherapy insensitivity, colorectal cancer, histone lactylation, polyploidy, glycolysis, SMC4 [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Evaluation of the prognostic and therapeutic potential of inhibin beta B for oral squamous cell carcinoma
Journal of Dental Science (Elsevier) Taiwan, 04 August 2023
Oncology
Key words: INHBB, Menin, Oral squamous cell carcinoma, Prognostic factor [more]
Organism: Human
Tissue: Mucosa
Pathological State: Cancer
Aberrant expression of interleukin-17A in mast cells contributes to the pathogenesis of hidradenitis suppurativa
British Journal of Dermatology (Oxford Academic) Taiwan, 04 August 2023
Immunology, Dermatology
Genetic and pharmacological inhibition of METTL3 alleviates renal fibrosis by reducing EVL m6A modification through an IGF2BP2‐dependent mechanism
Clinical and Translational Medicine (Wiley) China, 03 August 2023
Nephrology
Key words: chronic kidney disease, insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2),methyltransferase-like 3 (METTL3),N6-methyladenosine (m6A), renal fibrosis, traditional Chinese medicine [more]
Organism: Mouse
Tissue: Kidney
Pathological State: Renal fibrosis
Single-cell landscape of immune cells in human livers affected by HBV-related cirrhosis
JHEP Reports (Elsevier) China, Germany, UK, 03 August 2023
Immunology, Hepathology
Key words: Hepatitis B, Cirrhosis, Liver, Single-cell RNAseq, Immune cell [more]
Organism: Human
Tissue: Liver
Selection, identification and crystal structure of shark-derived single-domain antibodies against a green fluorescent protein
International Journal of Biological Macromolecules (Elsevier) China, 01 August 2023
Microscopy
Key words: Chiloscyllium plagiosum, Green fluorescent protein, Variable domain of new antigen receptors, Phage display, Crystal structure, Immunostaining [more]
Organism: Mouse
Tissue: Brain
Maternal di-(2-ethylhexyl) phthalate exposure elicits offspring IFN-λ upregulation: Insights from birth cohort, murine model, and in vitro mechanistic analysis
Food and Chemical Toxicology (Elsevier) Taiwan, 31 July 2023
Toxicology
Key words: IFNλ, di-(2-ethylhexyl) phthalate, Bronchial epithelium, Dendritic cell, PPARs, Histone modification
Scalable, flexible carbon fiber electrode thread arrays for three-dimensional probing of neurochemical activity in deep brain structures of rodents
Biosensors and Bioelectronics (Elsevier) USA, 30 July 2023
Neuroscience
Key words: Neural interface, Microelectrode array, Neurochemical probes, Dopamine sensors, Fast scan cyclic voltammetry, Striatum, Parkinson’s disease, Carbon fiber electrodes [more]
Organism: Rat
Tissue: Brain
Farnesoid X receptor activation inhibits pancreatic carcinogenesis
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (Elsevier) Germany, USA, 27 July 2023
Oncology
Key words: Pancreatic ductal adenocarcinoma, Pancreatic carcinogenesis, Farnesoid X receptor, Bile acid [more]
Organism: Mouse
Tissue: Pancreas
Pathological State: Cancer
The lncRNA HOXA11os regulates mitochondrial function in myeloid cells to maintain intestinal homeostasis
Cell Metabolism (Cell Press) USA, Israel, 25 July 2023
Gastroenterology
Key words: intestinal inflammation, colitis, IBD, mucosal inflammation, lncRNA, ncRNA, mitochondria, Krebs cycle, OXPHOS, complex I, mtROS [more]
Organism: Mouse
Tissue: Colon
Choice of Polymer, but Not Mesh Structure Variation, Reduces the Risk of Bacterial Infection with Staphylococcus aureus In Vivo
Biomedicines (MDPI) Germany, 24 July 2023
Tissue Engineering
Key words: mesh infection, hernia, foreign body reaction, mesh material, mesh structure [more]
Organism: Rat
Cell Line: Surgical mesh
B7-H3 confers stemness characteristics to gastric cancer cells by promoting glutathione metabolism through AKT/pAKT/Nrf2 pathway
Chinese Medical Journal (mednexus.org) China, 24 July 2023
Oncology
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
TRAF3/STAT6 axis regulates macrophage polarization and tumor progression
Cell Death & Differentiation (Nature) China, 21 July 2023
Oncology
Key words: Cancer microenvironment, Signal transduction, Ubiquitylation [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Microenvironmental and cell intrinsic factors governing human cDC2 differentiation and monocyte reprogramming
Frontiers in Immunology (Frontiers Media S.A.) Austria, 19 July 2023
Immunology
Key words: dendritic cell, Langerhans cell, transcriptional reprogramming, lineage decision, epidermal signaling, inflammatory skin disease [more]
Organism: Human
Tissue: Skin
Human intestine and placenta exhibit tissue-specific expression of RAGE isoforms
Heliyon (Cell Press) Austria, 18 July 2023
Reproductive Medicine
Key words: RAGE, Innate immune receptor, Alternative splicing, Small intestine, Colon, Placenta, Antibody validation [more]
Organism: Human
Tissue: Placenta
Aged-Signal-Eliciting Nanoparticles Stimulated Macrophage-Mediated Programmed Removal of Inflammatory Neutrophils
ACS Nano (ACS Publications) China, 17 July 2023
Nanomedicine
Key words: Biomimetic nanoparticles programmed cell removal aged signal activated neutrophils inflammation treatment [more]
Organism: Mouse
Tissue: Lung, Pancreas
Assessing the Effects of Nicotinamide Mononucleotide Supplementation on Pulmonary Inflammation in Male Mice Subchronically Exposed to Ambient Particulate Matter
Environmental Health Perspectives (EHP) China, USA, 17 July 2023
Pulmonology
Organism: Mouse
Tissue: Lung
Pathological State: Pulmonary Inflammation
FOXM1 is critical for the fitness recovery of chromosomally unstable cells
Cell Death & Disease (Nature) Germany, 14 July 2023
Oncology
Key words: Cancer, Cell biology [more]
Cell Line: Mouse breast tumor cells
S100A5 Attenuates Efficiency of Anti‐PD‐L1/PD‐1 Immunotherapy by Inhibiting CD8+ T Cell‐Mediated Anti‐Cancer Immunity in Bladder Carcinoma
Advanced Science (Wiley) China, 06 July 2023
Oncology, Immunology
Organism: Human
Tissue: Bladder
Pathological State: Cancer
A risk prognostic model for patients with esophageal squamous cell carcinoma basing on cuproptosis and ferroptosis
Journal of Cancer Research and Clinical Oncology (Springer) China, 05 July 2023
Oncology
Key words: Ferroptosis, Cuproptosis, Esophageal cancer, Clinicopathologic features, Tumor immune microenvironment [more]
Organism: Mouse
Tissue: Liver
Pathological State: Acute liver injury
Late Effects of Chronic Low Dose Rate Total Body Irradiation on the Heart Proteome of ApoE−/− Mice Resemble Premature Cardiac Ageing
Cancers (MDPI) Germany, USA, Italy, Japan, Germany, 29 June 2023
Cardiology
Key words: ionising radiation, TBI, chronic exposure, cardiovascular disease, ageing, proteomics, PPARα, TGFβ, SIRT, AMPK, heart, oxidative stress [more]
Organism: Mouse
Tissue: Heart
Umbelliferone and eriodictyol suppress the cellular entry of SARS-CoV-2
Cell & Bioscience (Springer) Taiwan, 28 June 2023
Pharmacology, SARS-CoV-2
Key words: Artemisia argyi, Eriodictyol, Umbelliferone, TMPRSS2, ACE2, SARS-CoV-2 variants [more]
Organism: Mouse
Tissue: Lung
Pathological State: SARS-CoV-2 Infection
Prognostic and immune infiltration significance of ARID1A in TCGA molecular subtypes of gastric adenocarcinoma
Cancer Medicine (Wiley) China, Japan, 27 June 2023
Oncology
Key words: ARID1A, gastric adenocarcinoma, immune infiltration, prognosis, TCGA subtype [more]
Organism: Human
Tissue: Stomach
Pathological State: Cancer
Extrafollicular IgD-CD27-CXCR5-CD11c-DN3 B cells infiltrate inflamed tissues in autoimmune fibrosis and in severe COVID-19
Cell Reports (Cell Press) USA, Canada, Japan, 27 June 2023
Immunology, SARS-CoV-2
Key words: double-negative B cells, DN3 B cells, extrafollicular B cells, COVID-19 pathogenesis, IgG4-related disease, inflammatory fibrosis, B cell depletion in disease, T-B collaboration in disease [more]
Organism: Human
Tissue: Lung, Submandibular Gland
Pathological State: COVID-19
Mesenchymal progenitor cells from non-inflamed versus inflamed synovium post-ACL injury present with distinct phenotypes and cartilage regeneration capacity
Stem Cell Research & Therapy (BMC) Canada, 25 June 2023
Stem Cell Research
Key words: Mesenchymal progenitor cells, Osteoarthritis, Inflammation, ACL injury [more]
Organism: Mouse
Tissue: Joint Tissue
Pathological State: Osteoarthritis
An integrative analysis of lipidomics and transcriptomics in various mouse brain regions in response to real-ambient PM2. 5 exposure
Science of The Total Environment (Elsevier) China, USA, 24 June 2023
Neuroscience
Key words: Fine particulate matter, Neurotoxicity, Multi-omics, Brain regions, Bile acid biosynthesis [more]
Organism: Mouse
Tissue: Brain
Crosstalk between myeloid and B cells shapes the distinct microenvironments of primary and secondary liver cancer
Cancer Research (AACR) China, 23 June 2023
Oncology
Key words: Tumor-infiltrating B cells, Tumor microenvironment, Liver cancer [more]
Organism: Human
Tissue: Liver
Pathological State: Cancer
A mitotic NADPH upsurge promotes chromosome segregation and tumour progression in aneuploid cancer cells
Nature Metabolism (Nature) China, 22 June 2023
Oncology
Key words: Cancer, Cancer metabolism, Metabolism, Mitosis [more]
Organism: Human
Tissue: Colon
Pathological State: Cancer
Chemokine receptor CXCR7 activates AURKA and promotes neuroendocrine prostate cancer growth
The Journal of Clinical Investigation (Am Soc Clin Investig) USA, China, Canada, 22 June 2023
Oncology
Organism: Human
Tissue: Prostate
Pathological State: Cancer
Analysis of Aldehyde Dehydrogenase 2 as a Prognostic Marker Associated with Immune Cell infiltration and Chemotherapy Efficacy in Head and Neck Squamous Cell Carcinoma
Journal of Cancer (Ivyspring International Publisher) Taiwan, 19 June 2023
Oncology, Pharmacology
Key words: Aldehyde Dehydrogenase 2, head and neck squamous cell carcinoma, human papillomavirus, tumor microenvironment, 5-fluorouracil [more]
Organism: Human
Tissue: Head and Neck
Pathological State: Cancer
Successful targeting in situ of an oncogenic nuclear antigen by hapten induced tumor associated autoantibodies (iTAA)
Scientific Reports (Nature) China, 19 June 2023
Oncology, Pharmacology
Key words: Biological techniques, Cancer, Chemical biology, Drug discovery, Immunology, Neuroscience [more]
Organism: Human
Tissue: Esophagus
Pathological State: Cancer
AlF-NOTA-FAPI-04 PET/CT can predict treatment response and survival in patients receiving chemotherapy for inoperable pancreatic ductal adenocarcinoma
European Journal of Nuclear Medicine and Molecular Imaging (Springer) China, 17 June 2023
Oncology
Key words: Fibroblast activation protein, Pancreatic adenocarcinoma, Metabolic tumor volume, Total lesion FAP expression [more]
Organism: Human
Tissue: Pancreas
Pathological State: Cancer
TOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway
Cell Death & Disease (Nature) China, 16 June 2023
Oncology
Key words: Immunochemistry, Oncogenes [more]
Organism: Human
Tissue: Esophagus
Pathological State: Cancer
Probiotic lactic acid bacteria alleviate pediatric IBD and remodel gut microbiota by modulating macrophage polarization and suppressing epithelial apoptosis
Frontiers in Microbiology (Frontiers Media S.A.) China, 15 June 2023
Microbiology
Key words: pediatric IBD, macrophage polarization, intestinal epithelium apoptosis, Akkermansia muciniphila, Pediococcus pentosaceus CECT8330 [more]
Organism: Mouse
Tissue: Colon
Pathological State: Inflammatory bowel disease
Inhibiting HIF-1 signaling alleviates HTRA1-induced RPE senescence in retinal degeneration
Cell Communication and Signaling (BMC) China, 14 June 2023
Ophthalmology
Key words: HTRA1, Hypoxia, HIF1α, Retinal pigment epithelium, Cell senescence, Age-related macular degeneration [more]
Organism: Mouse
Tissue: Eye
Pathological State: Retinal degeneration
SIRIUS, Ultra-Scintillating Upconversion Breast Implant for Remote Orthotopic Photodynamic Therapy
ACS Nano (ACS Publications) Singapore, Japan, 12 June 2023
Oncology, Pharmacology
Key words: Photodynamic therapy near-infrared upconversion nanoparticle implant breast cancer 5-aminolevulinic acid [more]
Organism: Mouse
Cyclophilin D as a potential therapeutic target of liver ischemia/reperfusion injury by mediating crosstalk between apoptosis and autophagy
Chronic Diseases and Translational Medicine (Wiley) China, 11 June 2023
Pharmacology, Hepathology
Key words: apoptosis, autophagy, cyclophilin D, ischemia/reperfusion, necrosis, reactive oxygen species [more]
Organism: Mouse
Tissue: Liver
Pathological State: liver ischemia/reperfusion injury
Exogenously delivered iPSCs disrupt the natural repair response of endogenous MPCs after bone injury
Scientific Reports (Nature) Canada, 09 June 2023
Osteology
Key words: Bone, Musculoskeletal system, Osteoporosis, Pluripotent stem cells [more]
Organism: Mouse
Tissue: Bone
Pathological State: Bone injury
RNF112-mediated FOXM1 ubiquitination suppresses the proliferation and invasion of gastric cancer
JCI insight (The American Society for Clinical Investigation) China, 08 June 2023
Gastroenterology, Oncology
Key words: Cancer gene therapy, Gastric cancer, Oncogenes [more]
Organism: Human
Tissue: Stomach
Pathological State: Cancer
Somatic mutations of CADM1 in aldosterone-producing adenomas and gap junction-dependent regulation of aldosterone production
Nature Genetics (Nature) UK, Malaysia, Japan, France, Singapore, Germany, USA, Czech Republic, Switzerland, 08 June 2023
Cardiology
Key words: Genetics research, Translational research [more]
Organism: Human
Tissue: Stomach
Pathological State: Cancer
Topical ozone accelerates diabetic wound healing by promoting re-epithelialization via activation of IGF1R-EGFR signaling
Journal of Investigative Dermatology (Elsevier) China, USA, 08 June 2023
Dermatology
Integrated Transcriptome and Metabolome Dynamic Analysis of Galls Induced by the Gall Mite Aceria pallida on Lycium barbarum Reveals the Molecular Mechanism Underlying Gall Formation and Development
International Journal of Molecular Sciences (MDPI) China, 07 June 2023
Botany
Key words: plant gall, gall mite, mite–plant interaction, gall development, molecular mechanism, transcriptome, metabolome, phytohormones [more]
Cell Line: Galls
The role of pores in micro-zone distribution of Cd in a tropical paddy soil: Results from X-ray computed tomography combined energy dispersive spectroscopy analysis
Journal of Hazardous Materials (Elsevier) China, USA, 07 June 2023
Ecology
Key words: Cadmium, Undisturbed tropical soil, Micro-zone distribution, Air space pores, Water-holding pores [more]
Cell Line: Soil
LA‐ICP‐MS analysis reveals differences in chemotherapeutic drug distribution in surgically resected pleural mesothelioma
British Journal of Clinical Pharmacology (Wiley) Hungary, Austria, Germany, Sweden, 05 June 2023
Oncology, Pharmacology
Key words: intratumoural drug distribution, laser ablation-inductively coupled plasma-mass spectrometry,mass spectrometry imaging, neoadjuvant chemotherapy, platinum, pleural mesothelioma [more]
Organism: Human
Pathological State: Cancer
Fluoxetine inactivates STAT3/NF-κB signaling and promotes sensitivity to cisplatin in bladder cancer
Biomedicine & Pharmacotherapy (Elsevier) Taiwan, 03 June 2023
Oncology
Key words: Muscles invasive bladder cancer, Fluoxetine, STAT3, NF-κB, Apoptosis [more]
Organism: Mouse
Tissue: Bladder, Allograft Tumor
Pathological State: Cancer
Axonal mapping of the motor cranial nerves
Frontiers in Neuroanatomy (Frontiers Media S.A.) Austria, USA, Switzerland, UK, 02 June 2023
Neuroscience
Key words: facial nerve, hypoglossal nerve, masseteric nerve, facial muscles, sensory feedback, sympathetic axons, motor control, proprioception [more]
Organism: Human
Tissue: Nerves
Lineage-specific accelerated sequences underlying primate evolution
Science Advances (Science) China, UK, 01 June 2023
Evolution
Organism: Human
Tissue: Brain
E7050 Suppresses the Growth of Multidrug-Resistant Human Uterine Sarcoma by Inhibiting Angiogenesis via Targeting of VEGFR2-Mediated Signaling Pathways
International Journal of Molecular Sciences (MDPI) Taiwan, USA, Malaysia, 31 May 2023
Oncology
Key words: E7050, VEGFR2, VEGF, multidrug-resistant human uterine sarcoma, angiogenesis [more]
Organism: Mouse
Tissue: Xenograft Tumor
Pathological State: Cancer
Gastroprotective effects of Machilus zuihoensis Hayata against acidic ethanol-induced gastric ulcer in mice
Journal of Traditional and Complementary Medicine (Elsevier) Taiwan, 31 May 2023
Gastroenterology
Key words: Gastroprotection, Mucus secretion, Antioxidation, Anti-inflammation, MAPK and NF-κB signaling pathways [more]
Organism: Mouse
Tissue: Stomach, Kidney, Liver
Pathological State: Gastric ulcer