Customer Publications (A total of 2648 papers published)

The vitamin D receptor activator paricalcitol prevents fibrosis and diastolic dysfunction in a murine model of pressure overload

Laura MG Meems, Megan V Cannon, Hasan Mahmud, Adriaan A Voors, Wiek H van Gilst, Herman HW Silljé, Willem PT Ruifrok, Rudolf A de Boer

The Journal of Steroid Biochemistry and Molecular Biology (Elsevier) The Netherlands, 15 July 2012

Cardiology

Key words: Fibrosis, heart failure, paricalcitol, remodeling, vitamin D receptor, renin [more]

Tumour‐secreted miR‐9 promotes endothelial cell migration and angiogenesis by activating the JAK‐STAT pathway

Guanglei Zhuang, Xiumin Wu, Zhaoshi Jiang, Ian Kasman, Jenny Yao, Yinghui Guan, Jason Oeh, Zora Modrusan, Carlos Bais, Deepak Sampath, Napoleone Ferrara

EMBO Journal (EMBO press) USA, 06 July 2012

Oncology

Key words: Angiogenesis, Endothelium, JAK‐STAT, MicroRNA, Tumour [more]

1107 In Vitro Generated Human Dendritic Cells Exposed to a Potent Maturation Melanoma Cell Lines Lysate Show a Tolerogenic-like Phenotype and Functionality When Exposed to Dexamethasone Prior to the Maturation Stimuli

C Falcon-Beas, F Tempio, B Pesce, J Aguillon, C Pereda, C Saffie, F Salazar-Onfray, MN Lopez

European Journal of Cancer (Elsevier) , 06 July 2012

Oncology

1110 Modulation of Genistein- and Resveratrol-induced Apoptosis and Cell Proliferation in Colon Cancer Cells

LI Brasoveanu, D Hotnog, C Hotnog, M Bostan, M Mihaila

European Journal of Cancer (Elsevier) , 06 July 2012

Oncology

1109 Density and Organization of B Cells, Including the Activation-induced Cytidine Deaminase (AID)-positive Sub-population, Within Active Tumor Border of Human Colorectal Cancer Liver Metastases Shows a Positive Association With Survival Prognosis

A Meshcheryakova, M Svoboda, E Bajna, J Maresch, J Jensen-Jarolim, M Bergmann, D Tamandl, D Mechtcheriakova

European Journal of Cancer (Elsevier) , 06 July 2012

Oncology

1108 Histidine-rich Glycoprotein Regulates Macrophage Differentiation

O Noguer, S Tugues, S Honjo, L Claesson-Welsh

European Journal of Cancer (Elsevier) , 06 July 2012

Oncology

Pristane-induced lupus as a model of human lupus arthritis: evolvement of autoantibodies, internal organ and joint inflammation

H Leiss, B Niederreiter, T Bandur, B Schwarzecker, S Blüml, G Steiner, W Ulrich3, JS Smolen, GH Stummvoll

Lupus (SAGE Journals) Austria, 01 July 2012

Rheumatology

Key words: Lupus arthritis pristane-induced lupus (PIL), systemic lupus erythematosus (SLE) [more]

A Novel Nucleus-Based Classifier for Discrimination of Osteoclasts and Mesenchymal Precursor Cells in Mouse Bone Marrow Cultures

Andreas Heindl, Alexander K Seewald, Martin Schepelmann, Radu Rogojanu, Giovanna Bises, Theresia Thalhammer, and Isabella Ellinger

International Journal of Medical and Health Sciences (Open Science Index) Austria, 01 July 2012

Osteology

Key words: osteoclasts, machine learning, ellipse fitting.

RasGRF1 regulates proliferation and metastatic behavior of human alveolar rhabdomyosarcomas

Maciej Tarnowski, Gabriela Schneider, Gabriele Amann, Geoffrey Clark, Peter Houghton, Frederic G Barr, Lukas Kenner, Mariusz Z Ratajczak, Magda Kucia

International Journal of Oncology (Spandidos Publications) USA, Austria, Poland, 28 June 2012

Oncology

[more]

Cisplatin and quantum dots encapsulated in liposomes as multifunctional nanocarriers for theranostic use in brain and skin

Li-Wen Zhang, Chih-Jen Wen, Saleh A Al-Suwayeh, Tzu-Chen Yen, Jia-You Fang

Journal of Nanoparticle Research (Springer) Taiwan, Saudi Arabia, 19 June 2012

Nanomedicine

Key words: Cdse zns qds, cdse zns nanocrystal, nude mouse skin, cdse zns quantum, cisplatin release, mouse skin section, blank liposome, cdse core, skin melanoma, vesicle size, quantum dot, entrapment efficiency, skin uptake, non-treatment group, cisplatin accumulation [more]

Monitoring neutrophils and platelets during casein-induced anaphylaxis in an experimental BALB/c mouse model

D Krishnamurti, P Starkl, K Szalai, F Roth-Walter, S C Diesner, M Mittlboeck, C Manhalter, E Untersmayr, E Jensen-Jarolim

Clinical and Experimental Allergy (Wiley) Austria, 15 June 2012

Allergy Research

Key words: Mast cells, basophils, alum-adsorbed casein, peripheral neutropenia

Quantitative analysis of binding sites for 9-fluoropropyl-(+)-dihydrotetrabenazine ([18F]AV-133) in a MPTP-lesioned PD mouse model

Ko-Ting Chao, Hsin-Hsin Tsao, Yi-Hsin Weng, Ing-Tsung Hsiao, Chia-Ju Hsieh, Shiaw-Pyng Wey, Tzu-Chen Yen, Mei-Ping Kung,Kun-Ju Lin

Synapse (Wiley) Taiwan, 13 June 2012

Neuroscience

Key words: Positron emission tomography, quantitative autoradiography, immunohistochemistry, vesicular monoamine transporter 2, standardized uptake value [more]

Prognostic role of indoleamine 2,3-dioxygenase in endometrial carcinoma

Renske A de Jong, Ido P Kema, Annemarie Boerma, H Marike Boezen, Johannes JL van der Want, Marloes JM Gooden, Harry Hollema, Hans W Nijman

Gynecologic Oncology (Elsevier) The Netherlands, 02 June 2012

Oncology

Key words: Endometrial carcinoma, indoleamine 2, 3-dioxygenase, T-lymphocytes, prognosis [more]

Evidence That Activated Hedgehog Signaling Predicts for Poor Clinical Outcome in Acute Myeloid Leukemia

Veronica Campbell, Eleni Tholouli, M Travis Quigley, John Keilty, Patrick Kelly, Karen McGovern, Margaret Read, Jeffery L Kutok, Richard Byers

Blood (American Society of Hematology) USA, UK, 01 June 2012

Oncology

Key words: Hedgehog (Hh), Acute Myeloid Leukemia (AML), Primary CD34+ myeloid blasts [more]

CD256 can be found in antibody-mediated renal allograft rejection tissues

Xu H, He X, Zhao W, Guo H, Shi Q, Zhu Y, Zhang X

Clinical Laboratory (NCBI) China, 01 June 2012

Transplantation Medicine

Key words: Tumor necrosis factor, Systemic lupus erythematosus, Rheumatoid arthritis, antibody-mediated rejection

Type 2 diabetes mellitus is associated with an imbalance in circulating endothelial and smooth muscle progenitor cell numbers

J van Ark, J Moser, C P H Lexis, F Bekkema, I Pop, I C C van der Horst, C J Zeebregts, H van Goor, B H R Wolffenbuttel, J L Hillebrands

Diabetologia (Springer) The Netherlands, 01 June 2012

Endocrinology

Key words: smc marker gene, smc differentiation, epc count, mature smc, angiogenic cell, fibrous cap, cell subset, smc lineage, mature ecs, vascular repair, atherosclerotic plaque, real-time rt-pcr, repair capacity, endothelial differentiation, cell mobilisation [more]

Point sur les avancées technologiques en hémocytométrie aux JIB 2011

F Berge, G Maggiore, A Frenkian

IRBM News (Elsevier) France, 01 June 2012

Cytometry

Chemical shift MR imaging methods for the quantification of transcatheter lipiodol delivery to the liver: preclinical feasibility studies in a rodent model

Xiaoming Yin, Yang Guo, Weiguo Li, Eugene Huo, Zhuoli Zhang, Jodi Nicolai, Robert A Kleps, Diego Hernando, Aggelos K Katsaggelos, Reed A Omary, Andrew C Larson

Radiology (Radiological Society of North America) USA, 01 June 2012

Medical Image Analysis

[more]

Clinical significance of the ratio between FOXP3 positive regulatory T cell and interleukin-17 secreting cell in renal allograft biopsies with acute T-cell-mediated rejection

Byung H Chung, Hye J Oh, Shang G Piao, Hyeon S Hwang, In O Sun, Sun R Choi, Hoon S Park, Bum S Choi, Yeong J Choi, Cheol W Park, Yong-SoKim, Mi-La Cho Chul W Yan

Immunology (Wiley) South Korea, 01 June 2012

Immunology

Key words: Acute T-cell-mediated rejection, FOXP3, interleukin-17, regulatory T cell, T helper type 17 [more]

96. Jahrestagung der Deutschen Gesellschaft für Pathologie e. V.

Der Pathologe (Springer) Germany, 27 May 2012

Pathology

Neural precursors (NPCs) from adult L967Q mice display early commitment to “in vitro” neuronal differentiation and hyperexcitability

Francesca DiFebo, Daniela Curti, Francesca Botti, Gerardo Biella, Paolo Bigini, Tiziana Mennini, Mauro Toselli

Experimental Neurology (Elsevier) Italy, 22 May 2012

Neuroscience

Key words: Neural stem/progenitor cells (NPCs), motoneuron, neurodegeneration, amyotrophic lateral sclerosis, wobbler mouse, sodium channel, hyperexcitability, patch-clamp [more]

Selective CDK4/6 inhibition with tumor responses by PD0332991 in patients with mantle cell lymphoma

John P Leonard, Ann S LaCasce, Mitchell R Smith, Ariela Noy, Lucian R Chirieac, Scott J Rodig, Jian Q Yu, Shankar Vallabhajosula, Heiko Schoder, Patricia English, Donna S Neuberg, Peter Martin, Michael M Millenson, Scott A Ely, Rachel Courtney, Naveed Shaik, Keith D Wilner, Sophia Randolph, Annick D Van den Abbeele, Selina Y Chen-Kiang, Jeffrey T Yap, Geoffrey I Shapiro

Blood (American Society of Hematology) USA, 17 May 2012

Oncology

Key words: Mantle cell lymphoma, cyclin D1–dependent kinase activity, bortezomib, temsirolimus, lenalidomide [more]

Snapshot spectral imaging using optimized diffractive optical elements

M De Biasio, T Arnold, A Tortschanoff, A Hermerschmidt, R Leitner

Next-Generation Spectroscopic Technologies (SPIE) Austria, Germany, 17 May 2012

Microscopy

Key words: snapshot, CTIS, DOE, optimization

RTEL1 contributes to DNA replication and repair and telomere maintenance

Evert-Jan Uringa, Kathleen Lisaingo, Hilda A Pickett, Julie Brind'Amour, Jan-Hendrik Rohde, Alex Zelensky, Jeroen Essers, Peter M Lansdorp

Molecular Biology of The Cell (American Society for Cell Biology) Canada, The Netherlands, Australia, 11 May 2012

Cell Biology

Key words: Telomere maintenance, DNA, mRtel1, embryonic stem cells [more]

Abating colon cancer polyposis by Lactobacillus acidophilus deficient in lipoteichoic acid

Khashayarsha Khazaie, Mojgan Zadeh, Mohammad W Khan, Praveen Bere, Fotini Gounari, Kirsten Dennis, Nichole R Blatner, Jennifer L Owen, Todd R Klaenhammerd, Mansour Mohamadzadeh

PNAS (PNAS) USA, 01 May 2012

Oncology

Key words: Dendritic cells regulatory, T cells anti-inflammatory [more]

Magnesium sulfate and nimesulide have synergistic effects on rescuing brain damage after transient focal ischemia

LC Wang, CY Huang, HK Wang, MH Wu, KJ Tsai

Journal of Neurotrauma (Mary Ann Liebert Inc.) Taiwan, 25 April 2012

Neuroscience

Key words: in vivo studies, ischemia, middle cerebral artery occlusion, therapeutic approach, stroke [more]

Mice lacking epidermal PPARγ exhibit a marked augmentation in photocarcinogenesis associated with increased UVB-induced apoptosis, inflammation and barrier dysfunction

Ravi P Sahu, Sonia C DaSilva, Badri Rashid, Kellie Clay Martel, Danielle Jernigan, Shama R Mehta, Deena R Mohamed, Samin Rezania, Joshua R Bradish, Andrew B Armstrong, Simon Warren, Raymond L Konger

International Journal of Cancer (Wiley) USA, 18 April 2012

Oncology

Key words: Photocarcinogenesis, peroxisome proliferators activated receptor gamma, inflammation, apoptosis, differentiation, nonmelanoma skin cancer [more]

Hedgehog pathway inhibitor saridegib (IPI-926) increases lifespan in a mouse medulloblastoma model

Michelle J Lee, Beryl A Hatton, Elisabeth H Villavicencio, Paritosh C Khanna, Seth D Friedman, Sally Ditzler, Barbara Pullar, Keith Robison, Kerry F White, Chris Tunkey, Michael LeBlanc, Julie Randolph-Habecker, Sue E Knoblaugh, Stacey Hansen, Andrew Richards, Brandon J Wainwright, Karen McGovern, James M Olson

PNAS (PNAS) USA, Australia, 04 April 2012

Oncology

Key words: Sonic Hedgehog (Shh) pathway, medulloblastomas, P-glycoprotein (Pgp)

Injection of Amniotic Fluid Stem Cells Delays Progression of Renal Fibrosis

Sargis Sedrakyan, Stefano Da Sacco, Anna Milanesi, Liron Shiri, Astgik Petrosyan, Radka Varimezova, David Warburton, Kevin V Lemley, Roger E De Filippo, Laura Perin

Journal of The American Society of Nephrology (JASN) USA, 01 April 2012

Nephrology

Key words: Stem cells, renal fibrosis [more]

Antagonistic effects of selenium and lipid peroxides on growth control in early hepatocellular carcinoma

Nataliya Rohr-Udilova, Wolfgang Sieghart, Robert Eferl, Dagmar Stoiber, Linda Björkhem-Bergman, Lennart C Eriksson, Klaus Stolze6 Hubert Hayden, Bernhard Keppler, Sandra Sagmeister, Bettina Grasl-Kraupp, Rolf Schulte-Hermann Markus Peck-Radosavljevic

Hepatology (Wiley) Austria, Sweden, 27 March 2012

Oncology

Key words: Vascular endothelial growth factor, hepatocellular carcinomas, antioxidative glutathione peroxidases [more]

Requirement of Cellular Prion Protein for Intestinal Barrier Function and Mislocalization in Patients With Inflammatory Bowel Disease

Constance SV Peti, Frédérick Barreau, Laura Besnie, Pierre Gandill, Béatrice Rivea, Danielle Chatea, Maryline Ro, Dominique Berreb, Magali Svrce, Philippe Cardo, Monique Rousse, Caroline Clai, Sophie Thenet

Gastroenterology (Elsevier) France, 22 March 2012

Gastroenterology

Key words: Tight Junction, mouse model, cell–cell adhesion, inflammation [more]

Biosafety of Non-Surface Modified Carbon Nanocapsules as a Potential Alternative to Carbon Nanotubes for Drug Delivery Purposes

Alan C L Tang, Gan-Lin Hwang, Shih-Jung Tsai, Min-Yao Chang, Zack C W Tang, Meng-Da Tsai, Chwan-Yao Luo, Allan S Hoffman, Patrick C H Hsieh

PLoS One (PLOS) Taiwan, USA, 22 March 2012

Nanomedicine

Key words: Carbon nanotubes, nanomaterials, drug delivery, toxicity, intravenous injections, cytokines, inflammation, alcohols [more]

Induction of intestinal pro-inflammatory immune responses by lipoteichoic acid

Mojgan Zadeh, Mohammad W Khan, Yong Jun Goh, Kurt Selle, Jennifer L Owen, Todd Klaenhammer, Mansour Mohamadzadeh

Journal of Inflammation (Springer) USA, 16 March 2012

Immunology

Key words: Dendritic cell, dextran sulfate sodium, inflammatory bowel disease, lipoteichoic acid, toll-like receptor 2 [more]

Comparative oncology: ErbB-1 and ErbB-2 homologues in canine cancer are susceptible to cetuximab and trastuzumab targeting

Josef Singer, Marlene Weichselbaumera, Thomas Stockner, Diana Mechtcheriakova, Yury Sobanov, Erika Bajna, Friedrich Wrba, Reinhard Horvat, Johann G Thalhammer, Michael Willmann, Erika Jensen-Jarolim

Molecular Immunology (Elsevier) Austria, 16 March 2012

Oncology

Key words: Comparative oncology, ErbB-1, ErbB-2, Human, Canine, Breast cancer [more]

Deficiency of the macrophage growth factor CSF-1 disrupts pancreatic neuroendocrine tumor development

SM Pyonteck, BB Gadea, HW Wang, V Gocheva, KE Hunter, LH Tang, JA Joyce

Oncogene (Nature) USA, 15 March 2012

Oncology

[more]

Involvement of the insular cortex in regulating glucocorticoid effects on memory consolidation of inhibitory avoidance training

R Fornari, R Wichmann, E Atucha, T Desprez, E Eggens-Meijer and B Roozendaal

Frontiers in behavioral neuroscience (Frontiers Media S.A.) The Netherlands, Brazil, 15 March 2012

Neuroscience

[more]

Preserved Function of Regulatory T Cells in Chronic HIV-1 Infection Despite Decreased Numbers in Blood and Tissue

Mathieu Angin, Douglas S Kwon, Hendrik Streeck, Fang Wen, Melanie King, Ashley Rezai, Kenneth Law, Tomoyuki C Hongo, Augustine Pyo, Alicja Piechocka-Trocha, Ildiko Toth, Florencia Pereyra, Musie Ghebremichael, Scott J Rodig, Danny A Milner Jr, James M Richter, Marcus Altfeld, Daniel E Kaufmann, Bruce D Walker, Marylyn M Addo

The Journal of Infectious Diseases (Oxford University Press) USA, 15 March 2012

Immunology, Virology

Key words: Regulatory T cells (Tregs), T lymphocytes, cytotoxic, lymphoid tissue (GALT) [more]

An Essential Role for Modulation of Hyperpolarization-Activated Current in the Development of Binaural Temporal Precision

Sukant Khurana, Zhiqiang Liu, Alan S Lewis, Kristen Rosa, Dane Chetkovich, Nace L Golding

Journal of Neuroscience (SFN) USA, 22 February 2012

Neuroscience

Key words: Medial superior olive, binaural neurons, hyperpolarization-activated current, cyclic nucleotide-gated (HCN) channels [more]

Regulation of Axonal HCN1 Trafficking in Perforant Path Involves Expression of Specific TRIP8b Isoforms

Wiebke Wilkars, Zhiqiang Liu, Alan S Lewis, Travis R Stoub, Elena M Ramos, Nicola Brandt, Daniel A Nicholson, Dane M Chetkovich, Roland A Bender

PLoS One (PLOS) Germany, USA, 21 February 2012

Neuroscience

Key words: Neurons, neuronal dendrites, axons, neuronal differentiation, immunohistochemistry techniques, pyramidal cells, in situ hybridization, hippocampus [more]

Inhibition of CD26/DPP-IV enhances donor muscle cell engraftment and stimulates sustained donor cell proliferation

Maura H Parker, Carol Loretz, Ashlee E Tyler, Lauren Snider, Rainer Storb, Stephen J Tapscott

Skeletal Muscle (Springer) USA, 16 February 2012

Regenerative Medicine

Key words: Muscular dystrophy, cell transplantation, xenotransplant, canine, CXCR4, diprotin A

Combined strategies of apomorphine diester prodrugs and nanostructured lipid carriers for efficient brain targeting

Kuo-Sheng Liu, Chih-Jen Wen, Tzu-Chen Yen, K C Sung, Ming-Chuan Ku, Jhi-Joung Wang, Jia-You Fang

Nanotechnology (IOP Science) Taiwan, Saudi Arabia, 10 February 2012

Nanomedicine

Key words: nanostructured lipid carriers, diacetyl apomorphine, diisobutyryl apomorphine, DAA, DIA [more]

Optimisation of the diffractive optical element for snapshot spectral imaging used in fluorescence microscopy

R Leitner, T Arnold, M De Biasio, G McGunnigle, R Rogojanu, G E Steiner, A Hermerschmidt

Computational Microscopy (SPIE) Austria, Germany, 09 February 2012

Microscopy

Key words: Luminescence, microscopy, optical components, maging spectroscopy, cameras, reconstruction algorithms, spectral resolution, spectrometers, imaging systems, computed tomography

Polycaprolactone electrospun mesh conjugated with an MSC affinity peptide for MSC homing in vivo

Zhenxing Shao, Xin Zhang, Yanbin Pi, Xiaokun Wang, Zhuqing Jia, Jingxian Zhu, Linghui Dai, Wenqing Chen, Ling Yin, Haifeng Chen, Chunyan Zhou, Yingfang Ao

Biomaterials (Elsevier) China, 07 February 2012

Biological Materials

Key words: Phage display, tssue engineering (TE), MSC-homing, peptide-modified polycaprolactone electrospun mesh [more]

Soy Isoflavone Supplementation for Breast Cancer Risk Reduction: A Randomized Phase II Trial

Seema A Khan, Robert T Chatterton, Nancy Michel, Michelle Bryk, Oukseub Lee, David Ivancic, Richard Heinz, Carola M Zalles, Irene B Helenowski, Borko D Jovanovic, Adrian A Franke, Maarten C Bosland, Jun Wang, Nora M Hansen, Kevin P Bethke, Alexander Dew, Margerie Coomes, Raymond C Bergan

Cancer Prevention Research (AACR Publications) USA, 05 February 2012

Oncology

Key words: breast cancer, breast epithelial proliferation, random fine-needle aspiration [more]

Single-walled carbon nanotubes induce airway hyperreactivity and parenchymal injury in mice

WY Hsieh, CC Chou, CC Ho, SL Yu, HY Chen, HYE Chou, JJW Chen, HW Chen, PC Yang

American Journal of Respiratory Cell and Molecular Biology (ATS Journals) Taiwan, 01 February 2012

Nanomedicine

Key words: single-walled carbon nanotubes, toxicity, matrix metalloproteinase2, cathepsin K, NF-κB [more]

Swine Leukocyte Antigen-DQ Expression and Its Regulation by Interferon-Gamma at the Maternal-Fetal Interface in Pigs

Mingoo Kim, Heewon Seo, Yohan Choi, Jangsoo Shim, Fuller W Bazer, Hakhyun Ka

Biology of Reproduction (SSR) South Korea, 01 February 2012

Reproductive Medicine

Key words: Endometrium female reproductive tract pig pregnancy reproductive immunology SLA-DQ uterus

Modulating intestinal immune responses by lipoteichoic acid-deficient Lactobacillus acidophilus

Mohammad W Khan, Mojgan Zadeh, Praveen Bere, Elias Gounaris, Jennifer Owen, Todd Klaenhammer, Mansour Mohamadzadeh

Immunotherapy (FSG) USA, 01 February 2012

Immunology

Key words: Microbe Lactobacillus acidophilus, lipoteichoic acid-deficient strain, dendritic cells and macrophages [more]

Lamin A/C protein is overexpressed in tissue-invading prostate cancer and promotes prostate cancer cell growth, migration and invasion through the PI3K/AKT/PTEN pathway

Lu Kong, Georg Schäfer Huajie Bu, Yong Zhang, Yuxiang Zhang, Helmut Klocker

Carcinogenesis (Oxford University Press) Austria, China, 21 January 2012

Oncology

Key words: cell growth, 1-phosphatidylinositol 3-kinase, cell lines, neoplasms, prostate cancer, pten gene, protein overexpression, proto-oncogene proteins c-akt, phosphoinositide 3-kinase, lamin type a [more]

Intratumoral heterogeneity in anaplastic large cell lymphoma of non-common subtype

Dmitriy Abramov, Ilske Oschlies, Dmitriy Konovalov, Christine Damm-Welk, Wilhelm Wössmann, Wolfram Klapper

Journal of Hematopathology (Springer) Germany, Russia, 14 January 2012

Oncology

Key words: Anaplastic large cell lymphoma, ALK, Digital image analysis [more]

Tubular epithelial syndecan-1 maintains renal function in murine ischemia/reperfusion and human transplantation

Celie JW, Katta KK, Adepu S, Melenhorst WB, Reijmers RM, Slot EM, Beelen RH, Spaargaren M, Ploeg RJ, Navis G, van der Heide JJ, van Dijk MC, van Goor H, van den Born J

Kidney international (Elsevier) The Netherlands, 11 January 2012

Nephrology

Key words: kidney transplantation, proliferation, renal epithelial cell, renal ischemia-reperfusion, transplant outcomes [more]

A role for Epstein–Barr viral BALF1 in facilitating tumor formation and metastasis potential

Wen-Li Hsua, Pei-Jung Chungb, Ming-Hsien Tsaia, Cicero Lee-Tian Changc, Chih-Lung Liang

Virus research (Elsevier) Taiwan, 02 January 2012

Oncology, Virology

Key words: EBV, BALF1, Transformation, Tumor, Metastasis [more]

Increased activation of the PI3K/AKT pathway compromises decidualization of stromal cells from endometriosis

X Yin, ME Pavone, Z Lu, JJ Wei, JJ Kim

Journal of Clinical Endocrinology and Metabolism (Oxford University Press) USA, 01 January 2012

Reproductive Medicine

[more]

Robotic Microscopy and information technology to increase accuracy, sensitivity and availability of blood cell analyses

V Medovyi, A Pyatnitskiy

Current Microscopy Contributions to Advances in Science and Technology (FORMATEX) Russia, 01 January 2012

Microscopy

Key words: robotic microscopy, blood smear analysis, virtual slide, laboratory telemedicine, image cytometry, virtual microscopy, image analysis, pattern recognition, artificial intelligence

Magnetization transfer MRI in pancreatic cancer xenograft models

Weiguo Li, Zhuoli Zhang, Jodi Nicolai, Guang-Yu Yang, Reed A Omary, Andrew C Larson

Magnetic Resonance in Medicine (Wiley) USA, 28 December 2011

Oncology

Key words: Magnetization transfer, fibrosis, pancreatic cancer, mouse xenograft model [more]

MicroRNA-1 and microRNA-206 improve differentiation potential of human satellite cells: a novel approach for tissue engineering of skeletal muscle

M Koning, PMN Werker, DWJ van der Schaft, RA Bank, MC Harmsen

Tissue Engineering Part A (Mary Ann Liebert Inc.) The Netherlands, 20 December 2011

Regenerative Medicine

[more]

Macrophages in human colorectal cancer are pro-inflammatory and prime T cells towards an anti-tumour type-1 inflammatory response

Siew-Min Ong, Yann-Chong Tan, Ottavio Beretta, Dongsheng Jiang, Wei-Hseun Yeap, June J Y Tai, Wing-Cheong Wong, Henry Yang, Herbert Schwarz, Kiat-Hon Lim, Poh-Koon Koh, Khoon-Lin Ling, Siew-Cheng Wong

European Journal of Immunology (Wiley) Singapore, 12 December 2011

Immunology

Key words: Chemokines, cytokines, spheroid model, T-cell co-stimulation, tumour-associated macrophages (TAMs) [more]

Sensorimotor assessment of the unilateral 6-hydroxydopamine mouse model of Parkinson's disease

KE Glajch, SM Fleming, DJ Surmeier, P Osten

Behavioural Brain Research (Elsevier) USA, 09 December 2011

Neuroscience

Key words: Parkinson's disease, 6-OHDA, Mouse, Behavioral test, Sensorimotor impairment, Medial forebrain bundle [more]

Digital Transplantation Pathology: Combining Whole Slide Imaging, Multiplex Staining and Automated Image Analysis

K Isse, A Lesniak, K Grama, B Roysam, M I Minervini A J Demetris

American Journal of Transplantation (Wiley) USA, 04 November 2011

Transplantation Medicine

Key words: Allograft pathology, C4d, digital image, fibrosis, quantitative analysis, quantum dots, three-dimensional imaging

Gas challenge–blood oxygen level-dependent (GC-BOLD) MRI in the rat Novikoff hepatoma model

Yang Guo, Ning Jin, Rachel Klein, Jodi Nicolai, Guang-Yu Yang, Reed A Omary, Andrew C Larson

Magnetic Resonance Imaging (Elsevier) USA, 04 November 2011

Oncology

Key words: Gas challenge–blood oxygen level dependent (GC-BOLD), MRI, Rat Novikoff hepatoma, Tumor angiogenesis, Tumor microvessel density [more]

Evaluation of Functional and Structural Alterations in Muscle Tissue after Short-Term Cold Storage in a New Tissue Preservation Solution

Wille T, Gonder S, Thiermann H,Seeger T,Rauen U, Worek F

Cells Tissues Organs (Karger) Germany, 01 November 2011

Regenerative Medicine

Key words: Muscle tissue, preservation solution [more]

Epithelial Area Detection in Cytokeratin Microscopic Images Using MSER Segmentation in an Anisotropic Pyramid

Cristian Smochina, Radu Rogojanu, Vasile Manta, Walter Kropatsch

Pattern Recognition in Bioinformatics (Springer) Romania, Austria, 01 November 2011

Medical Image Analysis

Key words: Crypt segmentation, Anisotropic diffusion pyramid, MSER, Biomedical imaging, Pathology, Microscopy, Fluorescence microscopy, Image analysis [more]

Impact of interleukin-21 in the pathogenesis of primary Sjogren's syndrome: increased serum levels of interleukin-21 and its expression in the labial salivary glands

Kwi Young Kang, Hyun-Ok Kim, Seung-Ki Kwok, Ji Hyeon Ju, Kyung-Su Park, Dong-Il Sun, Joo Yeon Jhun, Hye Jwa Oh, Sung-Hwan Park, Ho-Youn Kim

Arthritis Research and Therapy (Springer) South Korea, 26 October 2011

Rheumatology

Key words: Serum il-21, anti-ro ssa antibody, synovial membrane cell, labial salivary gland, il-21r expression, il-21 gene, anti-ro la antibody, salivary gland biopsy, tfh cell, ectopic germinal center, encephalitis, th17 cell, nkt cell, il-21 concentration, ductal cell [more]

Regulation of Oocyte and Cumulus Cell Interactions by Intermedin/Adrenomedullin 2

Chia Lin Chang, Hsin-Shih Wang, Yung-Kuei Soong, Shang Yu Huang, Shun Yuan Pa, Sheau Yu Teddy Hsu

Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) Taiwan, USA, 18 October 2011

Reproductive Medicine

Key words: Apoptosis, Bioinformatics, Cell Compartmentation, Cyclic AMP (cAMP), G Protein-coupled Receptors (GPCR), Ovary Peptide Hormones Adrenomedullin CGRP [more]

Sampling step importance in hierarchical semantic segmentation of microscopic images

Smochina C, Manta V, Kropatsch W

System Theory, Control, and Computing (IEEEXplore) Romania, Austria, 16 October 2011

Microscopy

Key words: Semantic segmentation of microscopic images

Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer

Tanaya Shree, Oakley C Olson, Benelita T Elie, Jemila C Kester, Alfred L Garfall, Kenishana Simpson, Katherine M Bell-McGuinn, Emily C Zabor, Edi Brogi, Johanna A Joyce

Genes and Development (CSH Press) USA, 12 October 2011

Oncology

Key words: Cancer metastasis, chemotherapy, tumor microenvironment, proteolysis paclitaxel [more]

Activation-Induced Cytidine Deaminase (AID)-Associated Multigene Signature to Assess Impact of AID in Etiology of Diseases with Inflammatory Component

Diana Mechtcheriakova, Yury Sobanov, Gabriele Holtappels, Erika Bajna, Martin Svoboda, Markus Jaritz, Claus Bachert, Erika Jensen-Jarolim

PLoS One (PLOS) Austria, Belgium, 03 October 2011

Immunology

Key words: Immunity, inflamation [more]

Evaluating the role of connexin43 in congenital heart disease: Screening for mutations in patients with outflow tract anomalies and the analysis of knock-in mouse …

GY Huang, LJ Xie, KL Linask, C Zhang, XQ Zhao, YI Yang, GM Zhou, YJ Wu, L Marquez-Rosado, DB McElhinney, E Goldmuntz, C Liu, PD Lampe, B Chatterjee, CW Lo

Journal of Cardiovascular Disease Research (Elsevier) USA, China, 01 October 2011

Cardiology

Key words: Connexin43, congenital heart disease, gap junction, knock-in mouse model, outflow tract, phosphorylations [more]

Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice

Kristina M Mueller, Jan-Wilhelm Kornfeld, Katrin Friedbichler, Leander Blaas, Gerda Egger, Harald Esterbauer, Peter Hasselblatt, Michaela Schlederer, Susanne Haindl, Kay-Uwe Wagner, David Engblom, Guenter Haemmerle, Dagmar Kratky, Veronika Sexl, Lukas Kenner, Andrey V Kozlov, Luigi Terracciano, Rudolf Zechner, Guenther Schuetz, Emilio Casanova, J Andrew Pospisilik, Markus H Heim, Richard Moriggl

Hepatology (Wiley) Austria, Germany, USA, Sweden, Switzerland, 27 September 2011

Oncology

Key words: Growth hormone (GH), peroxisome proliferator, systemic lipid homeostasis [more]

Soluble gp130 Regulates Prostate Cancer Invasion and Progression in an Interleukin-6 Dependent and Independent Manner

Shahrokh F Shariat, Thomas F Chromecki, Julia Hoefer, Christopher E Barbieri, Douglas S Scherr, Pierre I Karakiewicz, Claus G Roehrborn, Francesco Montoris, Zoran Culigd, Ilaria T Cavarretta

Journal of Urology (Elsevier) USA, Austria, Italy, Canada, 23 September 2011

Oncology

Key words: Prostate, prostatic neoplasms, neoplasm invasiveness, cytokine receptor gp130, biological markers [more]

Angiopoietin-Like 4 Regulates Epidermal Differentiation

Mintu Pal, Ming Jie Tan, Royston-Luke Huang, Yan Yih Goh, Xiao Ling Wang, Mark Boon Yang Tang, Nguan Soon Tan

PLoS One (PLOS) Singapore, 22 September 2011

Dermatology

Key words: Keratinocytes, cell differentiation, epidermis, immunoblotting, biopsy, DNA transcription, messenger RNA, wound healing [more]

Semantic Segmentation of Microscopic Images Using a Morphological Hierarchy

Cristian Smochina, Vasile Manta, Walter Kropatsch

Computer Analysis of Images and Patterns (Springer) Romania, Austria, 31 August 2011

Medical Image Analysis

Key words: Crypt segmentation, Morphological hierarchy, Biomedical imaging, Pathology, Microscopy [more]

Abstracts for the IFPA Meeting 2011

Placenta (Elsevier) Austria, 27 August 2011

Expression of the IGF Axis Is Decreased in Local Prostate Cancer but Enhanced after Benign Prostate Epithelial Differentiation and TGF-β Treatment

Petra Massoner, Michael Ladurner Rennau, Isabel Heidegger, Anita Kloss-Brandstätter, Monika Summerer, Eva Reichhart, Georg Schäfer, Helmut Klocker

The American Journal of Pathology (Elsevier) Austria, 26 August 2011

Oncology

Key words: Insulin-like growth factor (IGF), [more]

Higher infiltration by Th17 cells compared with regulatory T cells is associated with severe acute T-cell-mediated graft rejection

Byung Ha Chung, Hye Jwa Oh, Shang Guo Piao, In O Sun, Seok Hui Kang, Sun Ryoung Choi, Hoon Suk Park, Bum Soon Choi, Yeong Jin Choi, Cheol Whee Park, Yong-Soo Kim, Mi-La Cho and Chul Woo Yang

Experimental & Molecular Medicine (Nature) South Korea, 24 August 2011

Immunology

[more]

Modifiers of mutant huntingtin aggregation: functional conservation of C. elegans-modifiers of polyglutamine aggregation

Eva Teuling, Annika Bourgonje, Sven Veenje, Karen Thijssen, Jelle de Boer, Joeri van der Velde, Morris Swertz, Ellen Nollen

Plos Currents (PLOS) The Netherlands, 12 August 2011

Physiology

[more]

Spatiotemporal expression of SERPINE2 in the human placenta and its role in extravillous trophoblast migration and invasion

Schu-Rern Chern, Sheng-Hsiang Li, Chien-Ling Chiu, Hsiao-Ho Chang, Chih-Ping Chen, Edmund I Tsuen Chen

Reproductive Biology and Endocrinology (Springer) Taiwan, 02 August 2011

Reproductive Medicine

Key words: SERPINE2, plasminogen activator (PA) system, tissue remodeling, pregnancy, trophoblasts [more]

Herpesvirus Entry Mediator and Nectin-1 Mediate Herpes Simplex Virus 1 Infection of the Murine Cornea

Andrew H Karaba, Sarah J Kopp and Richard Longnecker

Journal of Virology (American Society for Microbiology) USA, 27 July 2011

Virology

Key words: Herpes, infection [more]

Expression of a functional VEGFR-1 in tumor cells is a major determinant of anti-PlGF antibodies efficacy

Jenny Yao, Xiumin Wu, Guanglei Zhuang, Ian M Kasman, Tobias Vogt, Vernon Phan, Masabumi Shibuya, Napoleone Ferrara, Carlos Bais

PNAS (PNAS) Japan, Italy, 12 July 2011

Oncology

Key words: Stroma tyrosine, kinase placental growth, factor vascular, endothelial growth, factor angiogenesis

Kupffer cells support extramedullary erythropoiesis induced by nitrogen-containing bisphosphonate in splenectomized mice

Hirotada Otsuka, Hideki Yagi, Yasuo Endo, Naoko Nonaka, Masanori Nakamura

Cellular Immunology (Elsevier) Japan, 05 July 2011

Immunology

Key words: Nitrogen-containing bisphosphonate (NBP), Kupffer cell, Extramedullary erythropoiesis [more]

Modeling Colon Adenocarcinomas in Vitro: A 3D Co-Culture System Induces Cancer-Relevant Pathways upon Tumor Cell and Stromal Fibroblast Interaction

Helmut Dolznig, Christian Rupp, Christina Puri, Christian Haslinger, Norbert Schweifer, Elisabeth Wieser, Dontscho Kerjaschki, Pilar Garin-Chesa

The American Journal of Pathology (Elsevier) Austria, 01 July 2011

Oncology

Key words: Colon adenocarcinoma, in vitro [more]

The Presence and Localization of Melatonin Receptors in the Rat Aorta

Martin Schepelmann, Lubos Molcan, Hana Uhrova, Michal Zeman, Isabella Ellinger

Cellular and Molecular Neurobiology (Springer) Austria, Slovakia, 22 June 2011

Neuroscience

Key words: Mt1 receptor, saponin, arterial stiffness, melatonin concentration, rhythmic gene expression, rat eyerenal artery, clock gene bmal1, nadph oxidase, pineal gland, nocturnal hypertension [more]

FTY720 Reduces Post-Ischemic Brain Lymphocyte Influx but Does Not Improve Outcome in Permanent Murine Cerebral Ischemia

Arthur Lie, Li Sun, Wei Zhou, Sönke Schwarting, Eva Mracsko, Markus Zorn, Henrike Bauer, Clemens Sommer, Roland Veltkamp

PLoS One (PLOS) Germany, 20 June 2011

Neuroscience

Key words: Ischemic strok e, Cerebral ischemia, Lymphocytes, Cytokines, T cells, Granulocytes, White blood cells, Monocytes

An rhs gene of Pseudomonas aeruginosa encodes a virulence protein that activates the inflammasome

Vanderlene L Kung, Sonal Khare, Christian Stehlik, Elizabeth M Bacon, Ami J Hughes, Alan R Hauser

PNAS (PNAS) USA, 09 June 2011

Pathology

Key words: Rhs element, YD repeat, pathogenesis

Spontaneous and aging-dependent development of arthritis in NADPH oxidase 2 deficiency through altered differentiation of CD11b+ and Th/Treg cells

Kihyun Lee, Hee Yeon Won, Myung Ae Bae, Jeong-Ho Hong, Eun Sook Hwang

PNAS (PNAS) South Korea, 07 June 2011

Rheumatology

Key words: Rheumatoid arthritis myeloid-derived suppressor cell

Vasculatures in Tumors Growing From Preirradiated Tissues: Formed by Vasculogenesis and Resistant to Radiation and Antiangiogenic Therapy

Fang-Hsin Chen, Chi-Shiun Chiang, Chun-Chieh Wang, Sheng-Yung Fu, Chien-Sheng Tsai, Shih-Ming Jung, Chih-Jen Wen, Chung-Chi Lee, Ji-Hong Hong

International Journal of Radiation Oncology*Biology*Physics (Elsevier) Taiwan, 27 May 2011

Oncology

Key words: Radiation, Tumor bed effects, Microvascular density, Green fluorescent protein–tagged bone marrow, Antiangiogenic therapy

Cytosolic DNA Triggers Inflammasome Activation in Keratinocytes in Psoriatic Lesions

Yvonne Dombrowski, Mark Peric, Sarah Koglin, Claudia Kammerbauer, Christine Göß, David Anz, Maren Simanski, Regine Gläser, Jürgen Harder, Veit Hornung, Richard L Gallo, Thomas Ruzicka, Robert Beschand, Jürgen Schauber

Science Translational Medicine (American Association for the Advancement of Science) Germany, USA, 11 May 2011

Dermatology

Key words: Psoriasis, keratinocytes, antimicrobial cathelicidin peptide LL-37,

Influence of melatonin on murine osteoclast formation in culture — Automated detection and quantification by a novel image analysis system

M Schepelmann, A Heindl, A Seewald, A Nussbaumer, G Bises, R Rogojanu, P Pietschmann, I Ellinger, T Thalhammer

Bone (Elsevier) Austria, 07 May 2011

Medical Image Analysis

Automated detection, quantification and characterization of osteoclasts in cultures using a combined image-processing and machine-learning strategy

A Heindl, M Schepelmann, R Stumberger, A Nussbaumer, c, P Pietschmann, G Bisesa, R Rogojanu, d, T Thalhammer, A Seewald, I Ellinger

Bone (Elsevier) Austria, 07 May 2011

Medical Image Analysis

Key words: Osteoclasts

The analysis of organic anion transporting polypeptide (OATP) mRNA and protein patterns in primary and metastatic liver cancer

Katrin Wlcek, Martin Svoboda, Juliane Riha, Susanna Zakaria, Ulrike Olszewski, Zdenek Dvorak, Franz Sellner, Isabella Ellinger, Walter Jäger, Theresia Thalhammer

Cancer Biology and Therapy (Taylor and Francis) Austria, 01 May 2011

Oncology

Key words: Polypeptides, cholangiocellular carcinoma, hepatocellular carcinoma

Segmentation of cell nuclei within chained structures in microscopic images of colon sections

C Smochina, A Serban, V Manta

Proceedings of the 27th Spring Conference on Computer Graphics (Association for Computing Machinery) Romania, 30 April 2011

Medical Image Analysis

Key words: Image segmentation, biomedical imaging, nucleus segmentation.

Aberrant expression of CD30 in neoplastic mast cells in high-grade mastocytosis

Sotlar K, Cerny-Reiterer S, Petat-Dutter K, Hessel H, Berezowska S, Müllauer L, Valent P, Horny HP

Modern Pathology (NCBI) Germany, 24 April 2011

Pathology

Key words: Neoplastic mast cells, mastocytosis, reactive mast cell hyperplasia

248 ANALYSIS AND CHARACTERIZATION OF HBVDNA INTEGRATION IN PATIENTS WITH OCCULT HBV INFECTION AND HEPATOCELLULAR CARCINOMA

C Saitta, T Pollicino, G Raffa, A Bertuccio, A Barbera, A Ciancio, A Smedile, G Navarra, G Raimondo

Journal of Hepatology (Elsevier) Italy, 18 April 2011

Oncology

[more]

247 MCL-1 IS A NEW P53 FAMILY TARGET GENE IN HEPATOCELLULAR CARCINOMA

A Pelc, K Roos, M Meinhard, H Mundt, B Besenbeck, H Schulze-Bergkamen, W Stremmel, M Müller

Journal of Hepatology (Elsevier) Germany, 18 April 2011

Oncology

246 NUCLEAR TRANSLOCATION OF C-JUN AND MALIGNANT POTENTIAL IN HEPATOCELLULAR CARCINOMA PATIENTS UNDERGOING ORTHOTOPIC LIVER TRANSPLANTATION

N Rohr-Udilova, W Sieghart, R Eferl, M Peck-Radosavljevic

Journal of Hepatology (Elsevier) , 18 April 2011

Transplantation Medicine

249 CHANGES IN TUMOR STIFFNESS FOR EARLY PREDICTION OF TUMOR RESPONSE TO SORAFENIB: A PROOF-OF-CONCEPT STUDY WITH ELASTOSONOGRAPHY IN AN ANIMAL MODEL OF HEPATOCELLULAR CARCINOMA (HCC)

V Salvatore, M Baron Toaldo, S Marinelli, C Palamà, L Gramantieri, M Cipone, L Bolondi, F Piscaglia

Journal of Hepatology (Elsevier) Italy, 18 April 2011

Oncology

Effector T-Cell Infiltration Positively Impacts Survival of Glioblastoma Patients and Is Impaired by Tumor-Derived TGF-β

Jennifer Lohr, Thomas Ratliff, Andrea Huppertz, Yingzi Ge, Christine Dictus, Rezvan Ahmadi, Stefan Grau, Nobuyoshi Hiraoka, Volker Eckstein, Rupert C Ecker, Thomas Korff, Andreas von Deimling, Andreas Unterberg, Philipp Beckhove, Christel Herold-Mende

Clinical Cancer Research (AACR Publications) Germany, 08 April 2011

Oncology

Key words: Tumor, flow citometry

Expression of organic anion-transporting polypeptides 1B3, 1B1, and 1A2 in human pancreatic cancer reveals a new class of potential therapeutic targets

Kounnis V, Ioachim E, Svoboda M, Tzakos A, Sainis I, Thalhammer T, Steiner G, Briasoulis E

OncoTargets and Therapy (Dove Press) Greece, Austria, 08 April 2011

Oncology

Key words: organic anion-transporting polypeptides, targeted therapy, transporter

Effect of Additional Boron on Tibias of African Ostrich Chicks

Jiayue Cheng, Kemei Peng, Erhui Jin, Yong Zhang, Yan Liu, Ningbo Zhang, Hui Song, Huazhen Liu, Zhonglin Tang

Biological Trace Element Research (Springer) China, 02 April 2011

Biological Materials

Key words: Ostrich chick, cortical bone thickness, bone volume fraction, boron intake, trabecular bone microarchitecture, boron addition, ovx rat, boron content, dietary boron bone strength, calcium phosphate, bone turnover, drinking water, bone mass

SERPINE2, an inhibitor of plasminogen activators, is highly expressed in the human endometrium during the secretory phase

Robert Kuo-Kuang Lee, Chi-Chen Fan, Yuh-Ming Hwu, Chung-Hao Lu, Ming-Huei Lin, Ying-Jie Chen, Sheng-Hsiang Li

Reproductive Biology and Endocrinology (Springer) Taiwan, 23 March 2011

Reproductive Medicine

Key words: protease nexin-1, plasminogen activators (PAs), SERPIN inhibitors, menstrual cycle

Hypoxia promotes proliferation of human myogenic satellite cells: a potential benefactor in tissue engineering of skeletal muscle

Merel Koning, Paul MN Werker, Marja JA van Luyn, and Martin C Harmsen

Tissue Engineering Part A (Mary Ann Liebert Inc.) The Netherlands, 23 March 2011

Regenerative Medicine

Phylogenetic discordance of human and canine carcinoembryonic antigen (CEA, CEACAM) families, but striking identity of the CEA receptors will impact …

Marlene Weichselbaumer, Michael Willmann, Martin Reifinger, Josef Singer, Erika Bajna, Yuriy Sobanov, Diana Mechtcherikova, Edgar Selzer, Johann G Thalhammer, Robert Kammerer, Erika Jensen-Jarolim

Plos Currents (PLOS) Austria, Germany, 16 March 2011

Oncology

Angiopoietin-like 4 Protein Elevates the Prosurvival Intracellular O2-: H2O2 Ratio and Confers Anoikis Resistance to Tumors

Pengcheng Zhu, Ming Jie Tan, Royston-Luke Huang, Chek Kun Tan, Han Chung Chong, Mintu Pal, Chee Ren Ivan Lam, Petra Boukamp, Jiun Yit Pan, Suat Hoon Tan, Sander Kersten, Hoi Yeung Li, Jeak Ling Ding, and Nguan Soon Tan

Cancer Cell (Cell Press) Singapore, 14 March 2011

Oncology

Antioxidant signaling via Nrf2 counteracts lipopolysaccharide-mediated inflammatory responses in foam cell macrophages

Anne-Marie Kuhn, Nico Tzieply, Martina Victoria Schmidt, Andreas von Knethen, Dmitry Namgaladze, Masayuki Yamamoto, Bernhard Brüne

Free Radical Biology and Medicine (Elsevier) Germany, Japan, 05 March 2011

Immunology

Key words: Foam cell, OxLDL, Nrf2, C/EBP, Desensitized phagocytes, Free radicals

Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells

Shilpee Dutt, Anupama Narla, Katherine Lin, Ann Mullally, Nirmalee Abayasekara, Christine Megerdichian, Frederick H Wilson, Treeve Currie, Arati Khanna-Gupta, Nancy Berliner, Jeffery L Kutok, Benjamin L Ebert

Blood (American Society of Hematology) USA, 03 March 2011

Physiology

Key words: Flow citometry, cell cycle analysis

Mast Cell 5-Lipoxygenase Activity Promotes Intestinal Polyposis in APCΔ468 Mice

Eric C Cheon, Khashayarsha Khazaie, Mohammad W Khan, Matthew J Strouch, Seth B Krantz, Joseph Phillips, Nichole R Blatner, Laura M Hix, Ming Zhang, Kristen L Dennis, Mohammed R Salabat, Michael Heiferman, Paul J Grippo, Hidayatullah G Munshi, Elias Gounaris, David J Bentrem

Cancer Research (AACR Publications) USA, 01 March 2011

Oncology

Key words: Arachidonic acid metabolism, colon carcinogenesis, hematopoietic 5-lipoxygenase (5LO), myeloid-derived suppressor cells (MDSCs)

Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke

Arthur Liesz, Wei Zhou, Éva Mracskó, Simone Karcher, Henrike Bauer, Sönke Schwarting, Li Sun, Dunja Bruder, Sabine Stegemann, Adelheid Cerwenka, Clemens Sommer, Alexander H Dalpke, Roland Veltkamp

Brain (Oxford University Press) Germany, 25 February 2011

Neuroscience

Key words: Brain ischaemia, T cellVLA-4VCAM-1, inflammation

In Vitro Dedifferentiation of Melanocytes from Adult Epidermis

Bernadett Kormos, Nóra Bels, Attila Bebes, Gábor Szabad, Sarolta Bacsa, Márta Széll, Lajos Kemény, Zsuzsanna Bata-Csörg

PLoS One (PLOS) Hungary, 23 February 2011

Dermatology

Key words: Melanocyts, Ultraviolet, Keratinocytes, Nestin, Cell differentiation, Protein expression, Adults, Epidermis

Single chain anti-c-Met antibody conjugated nanoparticles for in vivo tumor-targeted imaging and drug delivery

Ruei-Min Lu, Yu-Ling Chang, Min-Shan Chen, Han-Chung Wu

Biomaterials (Elsevier) Taiwan, 08 February 2011

Medical Imaging

Key words: c-Met, Phage display, scFv, Drug delivery system, Immunoliposome [more]

Adeno-associated virus-mediated anti-DR5 chimeric antibody expression suppresses human tumor growth in nude mice

Fujia Lv, Yuhe Qiu, Yaxi Zhang, Shilian Liu, Juan Shi, Yanxin Liu, Dexian Zheng

Cancer Letters (Elsevier) China, 08 February 2011

Oncology

Key words: Chimeric antibody, Death receptor 5, Gene transfer, Cancer therapy

Clinical and Cytological Effects of Pimecrolimus Cream 1% after Resolution of Active Atopic Dermatitis Lesions by Topical Corticosteroids: A Randomized Controlled Trial

Bangert C, Strober BE, Cork M, Ortonne J-P, Luger T, Bieber T, Ferguson A, Ecker RC, Kopp T, Weise-Riccardi S, Guettner A, Stingl G

Dermatology (Karger) Austria, USA, UK, France, Germany, 01 February 2011

Dermatology

Key words: Skin biopsies, dendritic cells, Langerhans cells, T cells, betamethasone-17α-valerate-induced AD

Irreversible electroporation in the liver: contrast-enhanced inversion-recovery MR imaging approaches to differentiate reversibly electroporated penumbra from Irreversibly Electroporated Ablation Zones

Yang Guo, Yue Zhang, Grace M Nijm, Alan V Sahakian, Guang-Yu Yang, Reed A Omary, Andrew C Larson

Radiology (Radiological Society of North America) USA, 01 February 2011

Hepathology

α-Catulin knockdown induces senescence in cancer cells

LC Fan, WF Chiang, CH Liang, YT Tsai, TY Wong, KC Chen, TM Hong, YL Chen

Oncogene (Nature) Taiwan, 31 January 2011

Oncology

Key words: Cancer, Gene regulation, Oncogenesis, Senescence

Entry of a heparan sulphate-binding HRV8 variant strictly depends on dynamin but not on clathrin, caveolin, and flotillin

Abdul Ghafoor Khan, Angela Pickl-Herk, Leszek Gajdzik, Thomas C Marlovits, Renate Fuchs, Dieter Blaas

Virology (Elsevier) Austria, 22 January 2011

Virology

Key words: Rhinovirus, Endocytosis, Dynamin, Macropinocytosis, Entry inhibitors, Endocytic pathway, Heparan sulphate, ICAM-1, Clathrin

Perifosine and CCI 779 Co-Operate to Induce Cell Death and Decrease Proliferation in PTEN-Intact and PTEN-Deficient PDGF-Driven Murine Glioblastoma

Kenneth L Pitter, Craig J Galbán, Stefanie Galbán, Omid Saeed-Tehrani, Fei Li, Nikki Charles, Michelle S Bradbury, Oren J Becher, Thomas L Chenevert, Alnawaz Rehemtulla, Brian D Ross, Eric C Holland, Dolores Hambardzumyan

PLoS One (PLOS) USA, 18 January 2011

Oncology

Key words: Glioma, Magnetic resonance imaging, Glioma cells, Adenocarcinomas, Cell death, In vivo imaging, Apoptosis

Detection of Nucleated Red Blood Cells in Maternal Circulation by Magnetic Sorting and in situ Hybridization

D Nemescu, D Constantinescu, V Martiniuc…

Gineco+ro () Romania, 01 January 2011

Reproductive Medicine

Key words: prenatal diagnosis, erythroblast, CD71, magnetic-activated cell sorting (MACS), flu o res cent in situ hybridization (FISH)

Novel Molecular Strategy Tests, Issued by Laparoscopy, That Can Predict the Progression and Severity of Endometriotic Disease

JB de la Joliniere, G Lesec, C Real, JM Ayoubi

Journal of Minimally Invasive Gynecology (AAGL) France, 01 January 2011

Reproductive Medicine

Enhanced sensitivity to Botulinum type A neurotoxin of human neuroblastoma SH-SY5Y cells after differentiation into mature neuronal cells

C Rasetti-Escargueil, CB Machado, R Preneta-Blanc

The Botulinum Journal (InderScience Publishers) UK, 01 January 2011

Toxicology

Key words: BoNT, Botulinum neurotoxin, neurotransmitter release, SH-SY5Y cell line, human neuroblastoma cells, differentiation, cell based assay, synaptic vesicles recycling.

Principles of Osteoimmunology

P Pietschmann

Principles of Osteoimmunology (Springer) Austria, 01 January 2011

Immunology

CORRELATIONS RELATED MORPHOFUNTIONAL ORGANIZATION OF ESOPHAGUS AND ITS TRANSPORT FUNCTION.

Goian, L, Veliceasa, B, Tărniceriu, Cristina Claudia, Frâncu, L L

Romanian Journal of Functional and Clinical, Macro- and Microscopical Anatomy and of Anthropology () Romania, 01 January 2011

Gastroenterology

THE QUALITATIVE MICROANATOMICAL ANALYSIS OF THE DISTRIBUTION OF THE INTRAMURAL BLOOD VESSELS IN THE ESOPHAGUS.

L Goian, CC Tărniceriu, LL Francu

Romanian Journal of Functional and Clinical, Macro- and Microscopical Anatomy and of Anthropology () Romania, 01 January 2011

Cardiology

Multifunctional hollow nanoparticles based on graft-diblock copolymers for doxorubicin delivery

Pei-Lin Lu, Yi-Chun Chen,Ta-Wei Ou, Hung-Hao Chen, Hsieh-Chih Tsai, Chih-Jen Wen, Chun-Liang Lo, Shiaw-Pyng Wey, Kun-Ju Lin,Tzu-Chen Yen, Ging-Ho Hsiu

Biomaterials (Elsevier) Taiwan, 22 December 2010

Biological Materials

Key words: Multifunctional hollow nanoparticles, Intracellular drug delivery, Cancer targeting, SPECT/CT imaging, Cancer therapy

Crucial function of histone deacetylase 1 for differentiation of teratomas in mice and humans

Sabine Lagger, Dominique Meunier, Mario Mikula, Reinhard Brunmeir, Michaela Schlederer, Matthias Artaker, Oliver Pusch, Gerda Egger, Astrid Hagelkruys, Wolfgang Mikulits, Georg Weitzer, Ernst W Muellner, Martin Susani, Lukas Kenner, Christian Seiser

EMBO Journal (EMBO Press) Austria, 20 December 2010

Oncology

Key words: Cancer treatment chromatinepigeneticsHDAC inhibitorshistone modifications

Lysophosphatidylcholine‐mediated functional inactivation of syndecan‐4 results in decreased adhesion and motility of dendritic cells

Johannes Bühligen, Mirko Himmel, Carl Gebhardt, Jan C Simon, Wolfgang Ziegler, Marco Averbeck

Journal of Cellular Physiology (Wiley) Germany, 15 December 2010

Cell Biology

Loss of ATM/Chk2/p53 Pathway Components Accelerates Tumor Development and Contributes to Radiation Resistance in Gliomas

Massimo Squatrito, Cameron W Brennan, Karim Helmy, Jason T Huse, John H Petrini, Eric C Holland

Cancer Cell (Cell Press) USA, 13 December 2010

Oncology

Key words: Glioblastoma mutliforme, DNA-damage response, ionizing radiation in vivo

Somatic Mutations throughout the Entire Mitochondrial Genome Are Associated with Elevated PSA Levels in Prostate Cancer Patients

Anita Kloss-Brandstätter, Georg Schäfer, Gertraud Erhart, Alexander Hüttenhofer, Stefan Coassin, Christof Seifarth, Monika Summerer, Jasmin Bektic, Helmut Klocker, Florian Kronenberg

American Journal of Human Genetics (Elsevier) Austria, 02 December 2010

Oncology

Key words: Somatic mitochondrial DNA (mtDNA) mutations, mitochondrial genes MT-CO2, MT-CO3, MT-ATP6, and MT-ND6, human mitochondrial genome

Neuronal hyperexcitability and seizures are associated with changes in glial–neuronal interactions in the hippocampus of a mouse model of epilepsy with mental retardation

Torun Melø, Paolo Bigini, Ursula Sonnewald, Silvia Balosso, Alfredo Cagnotto, Sara Barbera, Sarah Uboldi, Annamaria Vezzani, Tiziana Mennini

Journal of Neurochemistry (Wiley) Norway, Italy, 19 November 2010

Neuroscience

Key words: 13C nuclear magnetic resonance spectroscopy, astrocytes and microglia, glutamate and GABA, hippocampus, neuronal ceroid lipofuscinosis, seizures

Semi-automatic identification of punching areas for tissue microarray building: the tubular breast cancer pilot study

Federica Viti, Ivan Merelli, Mieke Timmermans, Michael den Bakker, Francesco Beltrame, Peter Riegman, Luciano Milanesi

BMC Bioinformatics (Springer) Italy, The Netherlands, 18 November 2010

Medical Image Analysis

Key words: Pixel Intensity, Pathological Region, Virtual Microscope, Donor Block, Unaffected Area

Nuclear localization of Nm23-H1 in head and neck squamous cell carcinoma is associated with radiation resistance

Haeng Ran Park, Se-Heon Kim, Sei Young Lee, Ji Min Sung, Ae Ran Park, Suki Kang, Baek Gil Kim, Yoon Pyo Choi, Yong-Bae Kim, Nam Hoon Cho

Cancer (Wiley) South Korea, 18 November 2010

Oncology

Key words: Nm23-H1, nuclear localization, radiation resistance, head and neck squamous cell carcinoma, predictor

Standards and impact of hematopathology in myelodysplastic syndromes (MDS)

Peter Valent, Attilio Orazi, Guntram Büsche, Annette Schmitt-Gräff, Tracy I George, Karl Sotlar, Berthold Streubel, Christine Beham-Schmid, Sabine Cerny-Reiterer, Otto Krieger, Arjan van de Loosdrecht, Wolfgang Kern, Kiyoyuki Ogata, Friedrich Wimazal, Judit Csomor, Judit Varkonyi, Wolfgang R Sperr, Martin Werner, Hans Kreipe, Horny Hans-Peter

Oncotarget (Impact Journals) Austria, Germany, Hungary, USA, Japan, The Netherlands, 16 November 2010

Oncology

Key words: MDS, hematopathology, diagnostic criteria, prognostication

p53 activation mediates polyglutamine-expanded ataxin-3 upregulation of Bax expression in cerebellar and pontine nuclei neurons

An-Hsun Chou, An-Chi Lin, Kue-Yi Hong, Su-Huei Hu, Ying-Ling Chen, Ju-Yu Chen, Hung-Li Wang

Neurochemistry International (Elsevier) Taiwan, 16 November 2010

Neuroscience

Key words: Spinocerebellar ataxia type 3, Polyglutamine-expanded ataxin-3, Cerebellum, Pontine nuclei, Bax,

The role of collagen receptors Endo180 and DDR-2 in the foreign body reaction against non-crosslinked collagen and gelatin

Qingsong Ye, Martin C Harmsen, Yijin Ren, Ruud A Bank

Biomaterials (Elsevier) The Netherlands, China, Australia, 10 November 2010

Biological Materials

Key words: Collagen, Gelatin, Endo180, DDR-2, Foreign body reaction, Giant cells

Highly malignant intra-hepatic metastatic hepatocellular carcinoma in rats

Y Guo, R Klein, RA Omary, GY Yang, AC Larson

American Journal of Translational Research (e-Century Publishing Corporation) USA, 01 November 2010

Hepathology

Key words: Hepatocellular carcinoma (HCC), rodent model, orthotopic implantation, N1-S1 rat HCC cell line, McARH7777 rat HCC cell line, MRI, histopathology

Spatiotemporal expression of the serine protease inhibitor, SERPINE2, in the mouse placenta and uterus during the estrous cycle, pregnancy, and lactation

Schu-Rern Chern, Sheng-Hsiang Li, Chung-Hao Lu, Edmund I Tsuen Chen

Reproductive Biology and Endocrinology (Springer) Taiwan, 27 October 2010

Reproductive Medicine

Key words: Estrous Cycle, Mouse Uterus, Trophoblast Giant Cell, Pregnant Uterus, Ectoplacental Cone

The anterior gradient 2 (AGR2) gene is overexpressed in prostate cancer and may be useful as a urine sediment marker for prostate cancer detection

Huajie Bu, Stefanie Bormann, Georg Schäfer, Wolfgang Horninger, Petra Massoner, Antje Neeb, Vinoth-Kumar Lakshmanan, Danilo Maddalo, Andrea Nestl, Holger Sültmann, Andrew CB Cato, Helmut Klocker

The Prostate (Wiley) Austria, Germany, 13 October 2010

Oncology

Key words: Urine prostate cancer marker, cell migration, cell-cycle progression, invasion, metastasis

Regulation of induced colonic inflammation by Lactobacillus acidophilus deficient in lipoteichoic acid

Mansour Mohamadzadeh, Erika A Pfeiler, Jeffrey B Brown, Mojgan Zadeh, Matthew Gramarossa, Elizabeth Managlia, Praveen Bere, Bara Sarraj, Mohammad W Khan, Krishna Chaitanya Pakanati, M Javeed Ansari, Sarah O'Flaherty, Terrence Barrett, Todd R Klaenhammer

PNAS (PNAS) USA, 12 October 2010

Immunology, Microbiology

Key words: Antiinflammatory lactobacilli Toll-like receptor 2 innate immunity

ABSTRACTS OF THE NINTH INTERNATIONAL CONFERENCE OF ANTICANCER RESEARCH

Anticancer Research (Anticancer Research) Greece, 10 October 2010

Oncology

Key words: Antitumor lymphocytes, ES cells, bioluminiscence imaging

Endo180 and MT1-MMP are involved in the phagocytosis of collagen scaffolds by macrophages and is regulated by interferon-gamma

Ye Q, Xing Q, Ren Y, Harmsen MC, Bank RA

European Cells and Materials (NCBI) The Netherlands, 07 October 2010

Regenerative Medicine

Key words: Hexamethylenediisocyanate, glutaraldehyde cross-linked sheep collagen,

Conditional IFNAR1 ablation reveals distinct requirements of Type I IFN signaling for NK cell maturation and tumor surveillance

Tatsuaki Mizutani, Nina Neugebauer, Eva M Putz, Nadine Moritz, Olivia Simma, Eva Zebedin-Brandl, Dagmar Gotthardt, Wolfgang Warsch, Eva Eckelhart, Hans-Peter Kantner, Ulrich Kalinke, Stefan Lienenklaus, Siegfried Weiss, Birgit Strobl, Mathias Müller, Veronika Sexl, Dagmar Stoiber

OncoImmunology (Taylor and Francis) Austria, Germany, 01 October 2010

Oncology

Key words: IFNAR1, IFNß, NK cells, leukemia, tumor surveillance

Transcriptional coactivators p300 and CBP stimulate estrogen receptor-beta signaling and regulate cellular events in prostate cancer

Jan Bouchal, Frédéric R Santer, Philipp PS Höschele, Eva Tomastikova, Hannes Neuwirt, Zoran Culig

The Prostate (Wiley) Austria, Czech Republic, 21 September 2010

Oncology

Key words: Transcriptional coactivators, prostate cancer, estrogen receptor-ß, migration, genistein

Physicochemical characterization and in vivo bioluminescence imaging of nanostructured lipid carriers for targeting the brain: apomorphine as a model drug

Shu-Hui Hsu, Chih-Jen Wen, S A Al-Suwayeh, Hui-Wen Chang, Tzu-Chen Yen, Jia-You Fang

Nanotechnology (IOP Science) Taiwan, 08 September 2010

Nanomedicine

Key words: Drug administration, Fluorescence microscopy, Drug release, Nuclear magnetic resonance, Brain Aqueous solutions, Saline Particle size, Transmission electron microscopy, Fluorescence, Nanoparticles Water Bioluminescence

Towards a versatile automated cell-detection system for science and diagnostics

Heindl, A, Dekan, S, Ellinger, I, Seewald, AK

Engineering in Medicine and Biology Society (IEEEXplore) Austria, 04 September 2010

Medical Image Analysis

Key words: Pixel, Proteins, Algorithm design and analysis, Histograms, Microscopy, Software tools

Self-assembling peptide amphiphile promotes plasticity of serotonergic fibers following spinal cord injury

Vicki M Tysseling, Vibhu Sahni, Eugene T Pashuck, Derin Birch, Amy Hebert, Catherine Czeisler, Samuel I Stupp, John A Kessler

Journal of Neuroscience Research (Wiley) USA, 03 September 2010

Neuroscience

Key words: Spinal cord injury, nanotechnology, biomaterials, regeneration, serotonin [more]

TGF-β IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer

Zhan Yao, Silvia Fenoglio, Ding Cheng Gao, Matthew Camiolo, Brendon Stiles, Trine Lindsted, Michaela Schlederer, Chris Johns, Nasser Altorki, Vivek Mittal, Lukas Kenner, Raffaella Sordella

PNAS (PNAS) USA, 31 August 2010

Oncology

Key words: Epidermal growth-factor receptor nonsmall cell lung cancer

Segmentation of cell nuclei within complex configurations in images with colon sections

Rogojanu, R, Bises, G, Smochina, C, Manta, V

Intelligent Computer Communication and Processing (IEEEXplore) Austria, Romania, 28 August 2010

Medical Image Analysis

Key words: Nuclei segmentation

MR imaging to assess immediate response to irreversible electroporation for targeted ablation of liver tissues: preclinical feasibility studies in a rodent model

Yue Zhang, Yang Guo, Ann B Ragin, Robert J Lewandowski, Guang-Yu Yang, Grace M Nijm, Alan V Sahakian, Reed A Omary, Andrew C Larson

Radiology (Radiological Society of North America) USA, 01 August 2010

Biological Methods

Tissue Microarrays in Cancer Research

Toby C Cornish, Angelo M De Marzo

Modern Molecular Biology (Springer) USA, 29 July 2010

Oncology

Key words: Tissue microarrays, formalin fixed, paraffin embedded tissue

Automated Analysis of Tissue Microarrays

Marisa Dolled-Filhart, Mark Gustavson, Robert L Camp, David L Rimm, John L Tonkinson, Jason Christiansen

Tissue Microarrays (Springer) USA, 21 July 2010

Medical Image Analysis

Key words: Immunohistochemistry, Automated analysis, AQUA, Tissue microarrays, Quantitative analysis, Biomarkers, Immunofluorescence

Neurons and Neuronal Stem Cells Survive in Glucose-Free Lactate and in High Glucose Cell Culture Medium During Normoxia and Anoxia

Sascha Wohnsland, Heinrich F Bürgers, Wolfgang Kuschinsky, Martin H Maurer

Neurochemical Research (Springer) Germany, Austria, 03 July 2010

Neuroscience

Key words: Global cerebral ischemia, hippocampal slice culture, glucose group, normoxic group, lactate concentration, organotypic slice culture, neuronal cell death, glucose deprivation, papain, neural progenitor cell, brain lactate, ketone body, iodide uptake, cortical neuron, rat pup

419 V600EB-RAF cooperates in Epithelial to Mesenquimal Transition regulating E-Cadherin and ILK-1 expression through the MEK/ERK-MAPK pathway

P Baquero, I Sánchez-Hernández, A Chiloeches

European Journal of Cancer (Elsevier) , 28 June 2010

Oncology

418 Differences in radiation, cisplatin, and cetuximab sensitivity between subpopulations of head and neck cancer cells

C Nilsson, L La Fleur, K Roberg

European Journal of Cancer (Elsevier) , 28 June 2010

Oncology

417 A c-Myc induced gene expression signature in human germinal center B cells predicts subtypes of aggressive non-Hodgkin Lymphoma

A Schrader, S Bentink, R Spang, D Lenze, M Hummel, M Kuo, P Murray, L Trümper, D Kube, M Vockerodt

European Journal of Cancer (Elsevier) , 28 June 2010

Oncology

416 Characterization and quantification of macrophages in colorectal cancer by an automated cell system

R Rogojanu, I Mesteri, I Ellinger, T Talhammer, E Kallay, A Heindl, A Seewald, G Bises

European Journal of Cancer (Elsevier) Austria, 28 June 2010

Medical Image Analysis

A Rat Model for Pressure Induced Deep Tissue Injury

Fang Lin, Mauli Modi, Briana Reprogle, Mike Bajema, Ziyan Wang, Gordon Kaskin, Mohsen Makhsous

ASME 2010 Summer Bioengineering Conference (ASME) USA, 16 June 2010

Biological Methods

Key words: Pressure, Biological tissues, Wounds

An advanced approach for the characterization of dendritic cell-induced T cell proliferation in situ

Christian Florian, Thomas Barth, Anja K Wege, Daniela N Männel, Uwe Ritter

Immunobiology (Elsevier) Germany, 09 June 2010

Immunology

Key words: BrdU incorporation, fluorochromes, lymph node, proliferation, T cells, TissueQuest

Neuropathologic and Biochemical Changes During Disease Progression in Liver X Receptor B_/_ Mice, A Model of Adult Neuron Disease

P Bigini, KR Steffensen, A Ferrario, L Diomede

Journal of Neuropathology and Experimental Neurology (American Association of Neuropathologists) USA, 01 June 2010

Neuroscience

Key words: Amytrophic lateral sclerosis, Cholesterol, CNS Inflammation, Glial cells, Liver X receptors, Motor neurons, Spinal neurons [more]

Neuropathologic and Biochemical Changes During Disease Progression in Liver X Receptor β−/− Mice, A Model of Adult Neuron Disease

Paolo Bigini, Knut R Steffensen, Anna Ferrario, Luisa Diomede, Giovanni Ferrara, Sara Barbera, Sonia Salzano, Elena Fumagalli, Pietro Ghezzi, Tiziana Mennini, Jan-Åke Gustafsson

Journal of Neuropathology and Experimental Neurology (Oxford University Press) USA, 01 June 2010

Neuroscience

Key words: Amyotrophic lateral sclerosis, Cholesterol, CNS inflammation, Glial cells, Liver X receptors, Motor neurons, Spinal neurons [more]

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

Frank Weinberg, Robert Hamanaka, William W Wheaton, Samuel Weinberg, Joy Joseph, Marcos Lopez, Balaraman Kalyanaraman, Gökhan M Mutlu, G R Scott Budinger, Navdeep S Chandel

PNAS (PNAS) USA, 11 May 2010

Oncology

Key words: Warburg Effect glutamine glycolysis lung cancer complex III

Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model

Benelita Tina Elie, Vasilena Gocheva, Tanaya Shree, Stacie A Dalrymple, Leslie J Holsinger, Johanna A Joyce

Biochimie (Elsevier) USA, 04 May 2010

Oncology

Key words: Cancer, Cysteine cathepsin, Protease, Therapy

Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase

Prakash G Chandak, Branislav Radovic, Elma Aflaki, Dagmar Kolb, Marlene Buchebner, Eleonore Fröhlich, Christoph Magnes, Frank Sinner, Guenter Haemmerle, Rudolf Zechner, Ira Taba, Sanja Levak-Fran, Dagmar Kratky

Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) Austria, USA, 27 April 2010

Cell Biology

Key words: ATP, Fatty Acid, Metabolism Glucose Lipase Lipid, Droplet Macrophage, Phagocytosis, Triacylglycerol

Automated segmentation of tissue images for computerized IHC analysis

S Di Cataldo, E Ficarra, A Acquaviva, E Macii

Computer Methods and Programs in Biomedicine (Elsevier) Italy, 01 April 2010

Medical Image Analysis

Key words: Immunohistochemistry, Tissue images, Tissue segmentation, Nuclear segmentation, Image processing

Rapid Pharmacokinetic and Biodistribution Studies Using Cholorotoxin-Conjugated Iron Oxide Nanoparticles: A Novel Non-Radioactive Method

Michelle Jeung-Eun Lee, Omid Veiseh, Narayan Bhattarai, Conroy Sun, Stacey J Hansen, Sally Ditzler, Sue Knoblaugh, Donghoon Lee, Richard Ellenbogen, Miqin Zhang, James M Olson

PLoS One (PLOS) USA, 04 March 2010

Medical Imaging

Key words: Nanoparticles, Spleen, Fluorescence imaging, Kidneys, Pharmacokinetics, Liver, Bone marrow, Iron oxides

Signal Transducer and Activator of Transcription 3 Protects From Liver Injury and Fibrosis in a Mouse Model of Sclerosing Cholangitis

Markus Mair, Gernot Zollner, Doris Schneller, Monica Mustean, Peter Fickert Judith Gumhol, Christian Schuste, Andrea Fuchsbichler, Martin Bilban, Stefanie Tauber, Harald Esterbauer, Lukas Kenner, Valeria Poli, Leander Blaas, Jan Wilhelm Kornfeld, Emilio Casanova, Wolfgang Mikulits, Michael Trauner, Robert Eferl

Gastroenterology (Elsevier) Austria, Germany, Italy, 26 February 2010

Gastroenterology

Key words: Stat3, Liver, Conditional Mouse Model, Cholestasis [more]

PI3Kγ Protects from Myocardial Ischemia and Reperfusion Injury through a Kinase-Independent Pathway

Bernhard J Haubner, G Gregory Neely, Jakob G J Voelkl, Federico Damilano, Keiji Kuba, Yumiko Imai, Vukoslav Komnenovic, Agnes Mayr, Otmar Pachinger, Emilio Hirsch, Josef M Penninger, Bernhard Metzler

PLoS One (PLOS) Austria, Italy, 22 February 2010

Cardiology

Key words: Reperfusion, Heart, Inflammation, Reperfusion injury, Infarction, Cardiac ventricles, Bone marrow cells, Bone marrow transplantation

Roles of hypoxia-inducible factor-1α (HIF-1α) versus HIF-2α in the survival of hepatocellular tumor spheroids

Heidi Menrad, Christian Werno, Tobias Schmid, Ekaterini Copanaki, Thomas Deller, Nathalie Dehne,Bernhard Brüne

Hepatology (Wiley) Germany, 19 February 2010

Hepathology

Key words: Hypoxia-inducible factors, hypoxic stress, tumor tissues, hepatocellular carcinoma, proapoptotic Bax

BMPR1a and BMPR1b Signaling Exert Opposing Effects on Gliosis after Spinal Cord Injury

Vibhu Sahni, Abhishek Mukhopadhyay, Vicki Tysseling, Amy Hebert, Derin Birch, Tammy L Mcguire, Samuel I Stupp, John A Kessler

Journal of Neuroscience (SFN) USA, 03 February 2010

Neuroscience

Key words: Spinal cord injury, bone morphogenetic protein, Western blot analysis [more]

Human Rhinovirus 14 Enters Rhabdomyosarcoma Cells Expressing ICAM-1 by a Clathrin-, Caveolin-, and Flotillin-Independent Pathway

Abdul Ghafoor Khan, Angela Pickl-Herk, Leszek Gajdzik, Thomas C Marlovits, Renate Fuchs, Dieter Blaas

Journal of Virology (American Society for Microbiology) Austria, 03 February 2010

Virology

Key words: Rhynovirus

Neutralization of Osteopontin Inhibits Obesity-Induced Inflammation and Insulin Resistance

Florian W Kiefer, Maximilian Zeyda, Karina Gollinger, Birgit Pfau, Angelika Neuhofer, Thomas Weichhart, Marcus D Säemann, René Geyeregger, Michaela Schlederer, Lukas Kenner, Thomas M Stulnig

Diabetes (Diabetes Journals) Austria, 27 January 2010

Endocrinology

Key words: Obesity, osteopontin, insulin sensitivity, fatty acid synthase (FAS), sterol regulatory element–binding protein-1c [more]

IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion

Vasilena Gocheva, Hao-Wei Wang, Bedrick B Gadea, Tanaya Shree, Karen E Hunter, Alfred L Garfall, Tara Berman, Johanna A Joyce

Genes and Development (CSH Press) USA, 15 January 2010

Oncology

Key words: Tumor-associated macrophage, tumor microenvironment, cysteine cathepsin protease, interleukin-4 invasion

Myosin light chain kinase mediates transcellular intravasation of breast cancer cells through the underlying endothelial cells: a three-dimensional FRET study

Satya Khuon, Luke Liang, Robert W Dettman, Peter H S Sporn, Robert B Wysolmerski, Teng-Leong Chew

Journal of Cell Science (The Company of Biologists) USA, 12 January 2010

Oncology

Key words: FRET imaging, Cytoskeletal signaling, Endothelium, Transcellular invasion, Tumor intravasation, Vascular engineering

Management of recurrence of symptoms of gastroesophageal reflux disease: synergistic effect of rebamipide with5 mg lansoprazole

N Yoshida, K Kamada, N Tomatsuri, T Suzuki, T Takagi, H Ichikawa, T Yoshikawa

Digestive diseases and Sciences (Springer) , 01 January 2010

Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice

Lisa Sevenich, Uta Schurigt, Kathrin Sachse, Mieczyslaw Gajda, Fee Werner, Sebastian Müller, Olga Vasiljeva, Anne Schwinde, Nicole Klemm, Jan Deussing, Christoph Peters, Thomas Reinheckel

PNAS (PNAS) Germany, 22 December 2009

Oncology

Key words: Lysosome mammary, adenocarcinoma, mouse model protease

In vivo labelling of resting monocytes in the reticuloendothelial system with fluorescent iron oxide nanoparticles prior to injury reveals that they are mobilized to infarcted myocardium

Karin Montet-Abou, Jean-Luc Daire, Jean-Noël Hyacinthe, Manuel Jorge-Costa, Kerstin Grosdemange, François Mach, Alke Petri-Fink, Heinrich Hofmann, Denis R Morel, Jean-Paul Vallée, Xavier Montet

European Heart Journal (Oxford University Press) Switzerland, 19 December 2009

Cardiology

Key words: Magnetic resonance imaging, Iron oxide nanoparticles, Inflammation, Myocardial infarction

Carbogen Gas–Challenge BOLD MR Imaging in a Rat Model of Diethylnitrosamine-induced Liver Fibrosis

Ning Jin, Jie Deng, Tamuna Chadashvili, Yue Zhang, Yang Guo, Zhuoli Zhang, Guang-Yu Yang, Reed A Omary, Andrew C Larson

Radiology (Radiological Society of North America) USA, 14 December 2009

Hepathology

Matrix metalloproteinase-9 mediates hypoxia-induced vascular leakage in the brain via tight junction rearrangement

Alexander T Bauer, Heinrich F Bürgers, Tamer Rabie, Hugo H Marti

Journal of Cerebral Blood Flow and Metabolism (SAGE Journals) Germany, 09 December 2009

Neuroscience

Key words: blood–brain barrier, hypoxia, in vivo, matrix metalloproteinase, occludin, vascular permeability

Interleukin-6 trans-signalling differentially regulates proliferation, migration, adhesion and maspin expression in human prostate cancer cells

Frédéric R Santer, Kamilla Malinowska, Zoran Culig, Ilaria T Cavarretta

Endocrine-Related Cancer (Society for Endocrinology) Austria, 04 December 2009

Oncology

Key words: IL-6 receptor, phosphotidylinositol 3-kinase, prostate cancer,

Stat3 Is a Negative Regulator of Intestinal Tumor Progression in ApcMin Mice

Monica Musteanu, Leander Blaas, Markus Mair, Michaela Schlederer, Martin Bilban Stefanie Tauber, Harald Esterbauer,Mathias Mueller, Emilio Casanova, Lukas Kenner, Valeria Poli, Robert Eferl

Gastroenterology (Elsevier) Austria, Italy, 04 December 2009

Oncology

Key words: APC, CEACAM1, Colorectal Cancer

Mimotope vaccination for therapy of allergic asthma: anti-inflammatory effects in a mouse model

J Wallmann, MM Epstein, P Singh, R Brunner, K Szalay, L El-Housseini, I Pali-Scholl, E Jensen-Jarolim

Clinical and Experimental Allergy (Wiley) Austria, 02 December 2009

Allergy Research

Key words: T lymphocytes, grass pollen allergens, Keyhole limpet haemocyanin (KLH)

Disruption of the growth hormone—Signal transducer and activator of transcription 5—Insulinlike growth factor 1 axis severely aggravates liver fibrosis in a mouse model of cholestasis

Leander Blaas, Jan-Wilhelm Kornfeld, Daniel Schramek, Monica Musteanu, Gernot Zollner, Judith Gumhold, Franziska van Zijl, Doris Schneller, Harald Esterbauer, Gerda Egger, Markus Mair, Lukas Kenner, Wolfgang Mikulits, Robert Eferl, Richard Moriggl, Josef Penninger, Michael Trauner, Emilio Casanova

Hepatology (Wiley) Austria, 30 November 2009

Hepathology

Key words: Liver Failure, Cirrhosis, Portal Hypertension [more]

Transient Protective Effect of B-Vitamins in Experimental Epilepsy in the Mouse Brain

Tamer Rabie, Wolfgang Mühlhofer, Thomas Bruckner, Anna Schwab, Alexander T Bauer, Manfred Zimmermann, Dieter Bonke, Hugo H Marti, Johannes Schenkel

Journal of Molecular Neuroscience (Springer) Germany, 24 September 2009

Neuroscience

Key words: Kainate administration, bcl-2 mrna expression, pyridoxine, kainate injection, tunel-positive cell, neuronal cell death, hippocampal ca3 region, genomic dna methylation, bcl-2 protein, dentate gyrus, follicular lymphoma, glutamate receptor, cognitive dysfunction, dead cell, saline-treated mouse

Epidermal loss of JunB leads to a SLE phenotype due to hyper IL-6 signaling

Pamina Pflegerl, Paul Vesely, Brigitte Hantusch, Michaela Schlederer, Rainer Zenz, Elke Janig, Günter Steiner, Arabella Meixner, Peter Petzelbauer, Peter Wolf, Afschin Soleiman, Gerda Egger, Richard Moriggl, Tadamitsu Kishimoto, Erwin F Wagner, Lukas Kenner

PNAS (PNAS) Austria, Spain, Japan, 15 September 2009

Dermatology

Key words: Epidermis IL-6R systemic lupus erythematosus

The potential role of c-Jun activation in patients with cutaneous lichen planus

Zuzana Marceková, Michael J Flaig, Maja Kekuš, Thomas Ruzicka, Rudolf A Rupec

Experimental Dermatology (Wiley) Germany, 15 September 2009

Oncology

Key words: C-Jun activation, immunohistochemistry, lichen planus, squamous cell carcinoma

Expression of sulfotransferases and sulfatases in human breast cancer: Impact on resveratrol metabolism

Michaela Miksits, Katrin Wlcek, Martin Svoboda, Theresia Thalhammer, Isabella Ellinger, Gabriele Stefanzl, Charles N Falany, Thomas Szekeres, Walter Jaeger

Cancer Letters (Elsevier) Austria, USA, 10 September 2009

Oncology

Key words: Resveratrol, Sulfation, Breast cancer, SULTs, Sulfatases, PCR, Immunofluorescence

COP1 contributes to UVB-induced signaling in human keratinocytes

Agnes Kinyo, Zsuzsanna Kiss-Laszlo, Szabolcs Hambalko, Attila Bebes, Maria Kiss, Marta Szell, Zsuzsanna Bata-Csörgo, Ferenc Nagy, Lajos Kemeny

Journal of Investigative Dermatology (Elsevier) Hungary, UK, 10 September 2009

Dermatology

The relationship between collagen scaffold cross-linking agents and neutrophils in the foreign body reaction

Qingsong Ye, Martin C Harmsen, Marja JA van Luyn, Ruud A Bank

Biomaterials (Elsevier) The Netherlands, China, Australia, 09 September 2009

Regenerative Medicine

Key words: Matrix metalloproteinase, Foreign body reaction, Giant cell formation, Phagocytosis, Interferon-gamma, Neutrophils

Down-regulation of Suppressor of Cytokine Signaling-3 Causes Prostate Cancer Cell Death through Activation of the Extrinsic and Intrinsic Apoptosis Pathways

Martin Puhr, Frédéric R Santer, Hannes Neuwirt, Martin Susani, Jeffrey A Nemeth, Alfred Hobisch, Lukas Kenner, Zoran Culig

Cancer Research (AACR Publications) Austria, USA, 08 September 2009

Oncology

Key words: Prostate cancer suppressor of cytokine signaling apoptosis extrinsic and intrinsic pathways

Organizational Issues in Providing High-Quality Human Tissues and Clinical Information for the Support of Biomedical Research

Walter C Bell, Katherine C Sexton, William E Grizzle

Cancer Gene Profiling (Springer) USA, 06 August 2009

Oncology

Key words: Human tissu, e Tissue banking, Tissue repository, Research infrastructure, IRB HIPAA

From virtual microscopy to systems pathology

Niels Grabe, Peter Schirmacher

Virchows Archiv (Springer) Germany, 04 August 2009

Microscopy

Vitamin D Analogs Differentially Control Antimicrobial Peptide/“Alarmin”Expression in Psoriasis

Mark Peric, Sarah Koglin, Yvonne Dombrowski, Katrin Groß, Eva Bradac, Amanda Büchau, Andreas Steinmeyer, Ulrich Zügel, Thomas Ruzicka, Jürgen Schauber

PLoS One (PLOS) Germany, 22 July 2009

Dermatology

Key words: Vitamin D, Keratinocytes, Psoriasis, Inflammation, ERK signaling cascade, Small interfering RNAs, Antimicrobials, Biopsy [more]

Novel mechanism of IGF-binding protein-3 action on prostate cancer cells: inhibition of proliferation, adhesion, and motility

Petra Massoner, Daniela Colleselli, Andrea Matscheski, Haymo Pircher, Stephan Geley, Pidder Jansen Dürr, Helmut Klocker

Endocrine-Related Cancer (Bioscientifica) Austria, 09 June 2009

Oncology

Key words: Prostate cancer, insulin-like growth factor (IGF), western-blot analysis

Sphingosine kinase 2 deficient tumor xenografts show impaired growth and fail to polarize macrophages towards an anti-inflammatory phenotype

Andreas Weigert, Susanne Schiffmann, Divya Sekar, Stephanie Ley, Heidi Menrad, Christian Werno, Sabine Grosch, Gerd Geisslinger, Bernhard Brüne

International Journal of Cancer (Wiley) Germany, 28 May 2009

Oncology

Key words: Cancer, angiogenesis, macrophages, sphingolipids, inflammation

Suppressor of Cytokine Signaling (SOCS)-1 Is Expressed in Human Prostate Cancer and Exerts Growth-Inhibitory Function through Down-Regulation of Cyclins and Cyclin-Dependent Kinases

Hannes Neuwirt, Martin Puhr, Frédéric R Santer, Martin Susani, Wolfgang Doppler, Gemma Marcias, Veronika Rauch, Maria Brugger, Alfred Hobisch, Lukas Kenner, Zoran Culig

The American Journal of Pathology (Elsevier) Austria, 01 May 2009

Oncology

Key words: Prostate cancer, gastric carcinoma, neck cancer, melanoma, chronic myleoid leukemia

Impaired Autolysosome Formation Correlates With Lamp-2 Depletion: Role of Apoptosis, Autophagy, and Necrosis in Pancreatitis

Franco Fortunato, Heinrich Bürgers, Frank Bergmann, Peter Rieger, Markus W Büchler, Guido Kroemer, Jens Werner

Gastroenterology (Elsevier) Germany, France, 09 April 2009

Gastroenterology

[more]

Coexpression of the melatonin receptor 1 and nestin in human breast cancer specimens

O Rögelsperger, C Ekmekcioglu, W Jäger, M Klimpfinger, R Königsberg, D Krenbek, F Sellner, T Thalhammer

Journal of Pineal Research (Wiley) Austria, 30 March 2009

Neuroscience

Key words: Breast cancer, MT1–nestin coexpression, immunofluorescence, quantification, TissueQuest [more]

Technical and Methodological Basics of Slide-Based Cytometry

Mittag A Bocsi J, Laffers W, Gerstner AOH

Cellular Diagnostics (Karger) Germany, 11 March 2009

Cytometry

Monocytes/macrophages in kidney allograft intimal arteritis: no association with markers of humoral rejection or with inferior outcome

Nicolas Kozakowski, Georg A Böhmig, Markus Exner, Afschin Soleiman, Nicole Huttary, Katalin Nagy-Bojarszky, Rupert C Ecker, Željko Kikic, Heinz Regele

Nephrology Dialysis Transplantation (Oxford University Press) Austria, 17 February 2009

Transplantation Medicine

Key words: Intimal arteritis, kidney allograft, lymphocyte, macrophage, monocyte [more]

Human Rhinovirus Type 2 Uncoating at the Plasma Membrane Is Not Affected by a pH Gradient but Is Affected by the Membrane Potential

Ursula Berka, Abdul Khan, Dieter Blaas, Renate Fuchs

Journal of Virology (American Society for Microbiology) Austria, 04 February 2009

Virology

[more]

Epidermal growth factor receptor is involved in enterocyte anoikis through the dismantling of E-cadherin-mediated junctions

Verónica-Haydée Lugo-Martínez, Constance S Petit, Stéphane Fouquet, Johanne Le Beyec, Jean Chambaz, Martine Pinçon-Raymond, Philippe Cardot, Sophie Thenet

Gastrointestinal and Liver Physiology (APS Journals) France, 01 February 2009

Gastroenterology

Key words: Intestinal epithelium [more]

Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke

Arthur Liesz, Elisabeth Suri-Payer, Claudia Veltkamp, Henrike Doerr, Clemens Sommer, Serge Rivest, Thomas Giese and Roland Veltkamp

Nature Medicine (Nature) Germany, Canada, 25 January 2009

Immunology, Neuroscience

[more]

The role of nanoparticle size in hemocompatibility

Andrea Mayer, Maria Vadon, Beate Rinner, Alexandra Novak, Reinhold Wintersteigerc, Eleonore Fröhlich

Toxicology (Elsevier) Austria, 22 January 2009

Toxicology

Key words: Nanotoxicology, Human blood, In vitro test system, Polystyrene particles, Particle siz, Surface charge, Nanoparticles [more]

The dark and the bright side of Stat3: proto-oncogene and tumor-suppressor

Andrea Ecker, Olivia Simma, Andrea Hoelbl, Lukas Kenner, Hartmut Beug, Richard Moriggl, Veronika Sexl

Frontiers in Bioscience (Frontiers Media S.A.) Austria, 01 January 2009

Oncology

[more]