Customer Publications (A total of 3040 papers published)

Houttuynia cordata Thunb Promotes Activation of HIF-1A–FOXO3 and MEF2A Pathways to Induce Apoptosis in Human HepG2 Hepatocellular Carcinoma Cells

Jung Min Kim, In-Hu Hwang, Ik-Soon Jang, Min Kim, In Seok Bang, Soo Jung Park, Yun-Jo Chung, Jong-Cheon Joo, Min-Goo Lee

Integrative Cancer Therapies (SAGE Journals) South Korea, 03 October 2016

Oncology

Key words: Cancer, cell apoptosis, hypoxia-inducible factor (HIF)-1A [more]

Hyperglycemia induces bioenergetic changes in adipose-derived stromal cells while their pericytic function is retained

Ghazaleh Hajmousa, Alvaro A Elorza, Vera JM Nies, Erik L Jensen, Ruxandra A Nagy, and Martin C Harmsen

Stem Cells and Development (Mary Ann Liebert Inc.) The Netherlands, Chile, 01 October 2016

Stem Cell Research

Key words: Adipose Derived Stromal Cells, Diabetic Retinopathy, Pericyte, Hyperglycemia [more]

NSAID-activated gene 1 mediates pro-inflammatory signaling activation and paclitaxel chemoresistance in type I human epithelial ovarian cancer stem-like cells

KH Kim, SH Park, KH Do, J Kim, KU Choi, Y Moon

Histochemistry and Cell Biology (NCBI) South Korea, 30 September 2016

Oncology

Key words: NAG-1, epithelial ovary cancer, paclitaxel, NF-κB, chemoresistance [more]

Interleukin-13 immune gene therapy prevents CNS inflammation and demyelination via alternative activation of microglia and macrophages

Caroline Guglielmetti,Debbie Le Blon, Eva Santermans, Angelica Salas-Perdomo, Jasmijn Daans, Nathalie De Vocht, Disha Shah, Chloé Hoornaert, Jelle Praet, Jurgen Peerlings, Firat Kara, Christian Bigot, Zhenhua Mai, Herman Goossens, Niel Hens, Sven Hendrix, Marleen Verhoye, Anna M Planas, Zwi Berneman, Annemie van der Linden, Peter Ponsaerts

GLIA (Wiley) Belgium, 29 September 2016

Neuroscience

Key words: IL-13, microglia, macrophages, severe oligodendrocyte loss and demyelination, mouse nodel [more]

Comparison of cancer cells cultured in 2D vs 3D reveals differences in AKT/mTOR/S6-kinase signaling and drug response

Angelika Riedl, Michaela Schlederer, Karoline Pudelko, Mira Stadler, Stefanie Walter, Daniela Unterleuthner, Christine Unger, Nina Kramer, Markus Hengstschläger, Lukas Kenner, Dagmar Pfeiffer, Georg Krupitza, Helmut Dolznig

Journal of Cell Science (The Company of Biologists) Austria, 23 September 2016

Oncology

Key words: Cancer cells, colon cancer, AKT/mTOR/S6-kinase, ERK phosphorylation [more]

Targeted multimodal nano-reporters for pre-procedural MRI and intra-operative image-guidance

Joonseok Lee, Andrew C Gordon, Hacksung Kim, Wooram Park, Soojeong Cho, Byeongdu Lee, Andrew C Larson, Elena A Rozhkova, Dong-Hyun Kim

Biomaterials (Elsevier) USA, 19 September 2016

Bioimaging

Key words: Upconversion nanoparticles, Medical imaging, Cancer, Interventional radiology, Multimodal probe [more]

CD103+ intraepithelial T cells in high-grade serous ovarian cancer are phenotypically diverse TCRαβ+ CD8αβ+ T cells that can be targeted for cancer immunotherapy

Fenne L Komdeur, Maartje CA Wouters, Hagma H Workel, Aline M Tijans, Anouk LJ Terwindt, Kim L Brunekreeft, Annechien Plat, Harry G Klip, Florine A Eggink, Ninke Leffers, Wijnand Helfrich, Douwe F Samplonius, Edwin Bremer, G Bea A Wisman, Toos Daemen, Evelien W Duiker, Harry Hollema, Hans W Nijman and Marco de Bruyn

Oncotarget (Impact Journals) The Netherlands, 16 September 2016

Oncology

Key words: tumor-infiltrating lymphocytes, high-grade serous ovarian cancer, CD103, TGF-β, cancer immunotherapy [more]

Expression and prognostic impact of immune modulatory molecule PD-L1 in meningioma

Seunggu J Han, Gerald Reis, Gary Kohanbash, Shruti Shrivastav, Stephen T Magill, Annette M Molinaro, Michael W McDermott, Philip V Theodosopoulos, Manish K Aghi, Mitchel S Berger, Nicholas A Butowski, Igor Barani, Joanna J Phillips, Arie Perry, Hideho Okada

Journal of Neuro-Oncology (Springer) USA, 13 September 2016

Neuroscience

Key words: Meningioma, PD-L1, B7-H1, Immunotherapy, Checkpoint, Lymphocyte, Macrophage [more]

Paricalcitol attenuates cardiac fibrosis and expression of endothelial cell transition markers in isoproterenol-induced cardiomyopathic rats

CC Lai, CP Liu, PW Cheng, PJ Lu, M Hsiao, WH Lu, GC Sun, JC Liou, CJ Tseng

Critical Care Medicine (Ingentaconnect) Taiwan, 09 September 2016

Cardiology

Key words: cardiac fibrosis, cardiomyopathy, endothelial-to-mesenchymal cell transition, vitamin D activator [more]

The effects of oral and topical corticosteroid in rabbit corneas

Kaoru Araki-Sasaki, Osamu Katsuta, Hidetoshi Mano, Takashi Nagano and Masatsugu Nakamura

BMC Ophthalmology (BioMed Central) Japan, 05 September 2016

Ophthalmology

Key words: Corticosteroid, Keratitis, Cornea, Wound healing, Pharmacokinetics [more]

Presentation of underglycosylated mucin 1 in pancreatic adenocarcinoma (PDAC) at early stages

ST Lo, P Pantazopouos, Z Medarova, A Moore

American Journal of Cancer Research (NCBI) USA, 01 September 2016

Oncology

Key words: Pancreatic cancer, underglycosylated mucin 1, tumor antigen, immunohistochemistry [more]

Neural stem cells secrete factors facilitating brain regeneration upon constitutive Raf-Erk activation

Yong-Hee Rhee, Sang-Hoon Yi, Joo Yeon Kim, Mi-Yoon Chang, A-Young Jo, Jinyoung Kim, Chang-Hwan Park, Je-Yoel Cho, Young-Jin Choi, Woong Sun and Sang-Hun Lee

Scientific Reports (Nature) South Korea, 24 August 2016

Neuroscience

Key words: Neurology, neural stem cells, Raf-Erk pathway, radial glial cells [more]

Degradation of Kidney and Psoas Muscle Proteins as Indicators of Post-Mortem Interval in a Rat Model, with Use of Lateral Flow Technology

Dong-Gi Lee, Kyeong Eun Yang, Jeong Won Hwang, Hwan-Soo Kang, Seung-Yeul Lee, Seoyeon Choi, Joonchul Shin, Ik-Soon Jang, Hyun Joo An, Heesun Chung, Hyo-Il Jung, Jong-Soon Choi

PLoS One (PLOS) South Korea, 23 August 2016

Forensic Science

Key words: Post-mortem interval (PMI) markers, kidney, muscle, GAPDH [more]

Toward the Automated Detection and Characterization of Osteoclasts in Microscopic Images

Andreas Heindl, Martin Schepelmann, Robert Nica, Rupert Ecker, Peter Pietschmann, Alexander K Seewald, Theresia Thalhammer, Isabella Ellinger

Principles of Osteoimmunology (Springer) Austria, 19 August 2016

Medical Image Analysis

Key words: Osteoimmunology, microscopes, biological samples, automated image segmentation and analysis

LIN28A enhances the therapeutic potential of cultured neural stem cells in a Parkinson's disease model

Yong-Hee Rhee, Tae-Ho Kim, A-Young Jo, Mi-Yoon Chang, Chang-Hwan Park, Sang-Mi Kim, Jae-Jin Song, Sang-Min Oh, Sang-Hoon Yi, Hyeon Ho Kim, Bo-Hyun You, Jin-Wu Nam, Sang-Hun Lee

Brain: A journal of neurology (Oxford University Press) South Korea, 18 August 2016

Neuroscience

Key words: LIN28A, neural stem cell (NSC) culture, repair capacity, Parkinson's disease [more]

Dynamic Modulation of Microglia/Macrophage Polarization by miR-124 after Focal Cerebral Ischemia

Somayyeh Hamzei Taj, Widuri Kho, Markus Aswendt, Franziska M Collmann, Claudia Green, Joanna Adamczak, Annette Tennstaedt, Mathias Hoehn

Journal of Neuroimmune Pharmacology (Springer) Germany, 18 August 2016

Neuroscience

Key words: Stroke, Microglia/macrophage polarization, Pro-inflammatory and anti-inflammatory phenotypes, miRNA-124, Neuroinflammation [more]

The antiviral alkaloid berberine reduces chikungunya virus-induced mitogen-activated protein kinase (MAPK) signaling

Finny S Varghese, Bastian Thaa, Siti Naqiah Amrun, Diane Simarmata, Kai Rausalu, Tuula A Nyman, Andres Merits, Gerald M McInerney2, Lisa FP Ng, Tero Ahola

Journal of Virology (American Society for Microbiology) Finland, 17 August 2016

Virology

Key words: Chikungunya virus, non-toxic plant alkaloid berberine, mitogen-activated protein kinase [more]

Bradykinin promotes neuron-generating division of neural progenitor cells via ERK activation

Micheli M Pillat, Claudiana Lameu, Cleber A Trujillo, Talita Glaser, Angélica R Cappellari, Priscilla D Negraes, Ana M O Battastini, Telma T Schwindt, Alysson Muotri, Henning Ulrich

Journal of Cell Science (The Company of Biologists) Brazil, 15 August 2016

Neuroscience

Key words: Bradykinin, neurogenesis, TIS21 (PC3/BTG2) expression [more]

G9a/RelB regulates self-renewal and function of colon-cancer-initiating cells by silencing Let-7b and activating the K-RAS/β-catenin pathway

Shih-Ting Cha, Ching-Ting Tan, Cheng-Chi Chang, Chia-Yu Chu, Wei-Jiunn Lee, Been-Zen Lin, Ming-Tsan Lin and Min-Liang Kuo

Nature Cell Biology (Nature) Taiwan, 15 August 2016

Oncology

Key words: Colorectal cancer, cancer-initiating cells phenotypes, K-RAS/β-catenin pathway [more]

Prevention of Colitis and Colitis-Associated Colorectal Cancer by a Novel Polypharmacological Histone Deacetylase Inhibitor

Tzu-Tang Wei, Yi-Ting Lin, Ruo-Yu Tseng, Chia-Tung Shun, Yu-Chin Lin, Ming-Shiang Wu, Jim-Min Fang, Ching-Chow Chen

Clinical Cancer Research (AACR Publications) Taiwan, 14 August 2016

Oncology

Key words: Colorectal cancer, colitis, HDAC, HMGR [more]

Localization of TrkB and p75 receptors in peritoneal and deep infiltrating endometriosis: an immunohistochemical study

Agung Dewanto, Jozsef Dudas, Rudolf Glueckert, Sylvia Mechsner, Anneliese Schrott-Fischer, Ludwig Wildt and Beata Seeber

Reproductive Biology and Endocrinology (Springer) Germany, 12 August 2016

Reproductive Medicine

Key words: Neurotrophins,  BDNF,  endometriosis,  immunohistochemistry [more]

Hypoxia-inducible factor-1α promotes glomerulosclerosis and regulates COL1A2 expression through interactions with Smad3

Bethany Baumann, Tomoko Hayashida, Xiaoyan Liang, H William Schnaper

Kidney International (Elsevier) USA, 05 August 2016

Physiology

Key words: Fibrosis, glomerulus, hypoxia, TGF-β [more]

Role of the immune system in the peritoneal tumor spread of high grade serous ovarian cancer

Katharina Auer, Anna Bachmayr-Heyda, Nyamdelger Sukhbaatar, Stefanie Aust, Klaus G Schmetterer, Samuel M Meier, Christopher Gerner, Christoph Grimm, Reinhard Horvat, and Dietmar Pils

Oncotarget (Impact Journals) Austria, 03 August 2016

Oncology

Key words: epithelial ovarian cancer, peritoneal tumor spread, flow cytometry, PD-1, next generation sequencing [more]

Sur8 mediates tumorigenesis and metastasis in colorectal cancer

Young-Mi Lee, Saluja Kaduwal, Kug Hwa Lee, Jong-Chan Park, Woo-Jeong Jeong, Kang-Yell Choi

Experimental & Molecular Medicine (Nature) South Korea, 29 July 2016

Oncology

Key words: Scaffold protein, Ras-extracellular signal-regulated kinase, doxycyline, HCT116 cells [more]

CD271 regulates the proliferation and motility of hypopharyngeal cancer cells

Mai Mochizuki, Keiichi Tamai, Takayuki Imai, Sayuri Sugawara, Naoko Ogama, Mao Nakamura, Kazuto Matsuura, Kazunori Yamaguchi, Kennichi Satoh, Ikuro Sato, Hozumi Motohashi, Kazuo Sugamura, Nobuyuki Tanaka

Scientific Reports (Nature) Japan, 29 July 2016

Oncology

Key words: CD271 (p75 neurotrophin receptor), human hypopharyngeal cancer, head and neck squamous cell carcinoma [more]

Regulation of actin dynamics by WNT-5A: implications for human airway smooth muscle contraction

Tim Koopmans, Kuldeep Kumawat, Andrew J Halayko, Reinoud Gosens

Scientific Reports (Nature) The Netherlands, 29 July 2016

Cell Biology

Key words: Airway hyperresponsiveness, asthm, intracellular calcium flux, actin polymerisation [more]

Tissue-Resident CD169+ Macrophages Form a Crucial Front Line against Plasmodium Infection

Pravesh Gupta, Si Min Lai, Jianpeng Sheng, Piotr Tetlak, Akhila Balachander, Carla Claser, Laurent Renia, Klaus Karjalainen, Christiane Ruedl

Cell Reports (Cell Press) Singapore, 28 July 2016

Cell Biology

Key words: Plasmodium berghei ANKA, malaria, myeloid cells, macrophages [more]

In situ mapping of innate lymphoid cells in human skin: evidence for remarkable differences between normal and inflamed skin

Marie-Charlotte Brüggen, Wolfgang M Bauer, Bärbel Reininger, Eduard Clim, Catalin Captarencu Georg E Steiner, Patrick M Brunner, Barbara Meier, Lars E French, Georg Sting

Journal of Investigative Dermatology (Elsevier) Austria, Switzerland, Romania, 22 July 2016

Dermatology

Key words: Lymphoid Cells, Human Skin, Inflamed Skin, atopic dermatitis, psoriasis [more]

4 – Proffered Paper: Immunological changes during tumor progression from primary to recurrent glioblastoma

C Herold-Mende, C Rapp, R Warta, A Unterberg, P Beckhove

European Journal of Cancer (Elsevier) , 14 July 2016

Oncology

Key words: Cancer, tumor, glioblastoma [more]

Multimodal Imaging of Nanocomposite Microspheres for Transcatheter Intra-Arterial Drug Delivery to Liver Tumors

Dong-Hyun Kim, Weiguo Li, Jeane Chen, Zhuoli Zhang, Richard M Green, Sui Huang and Andrew C Larson

Scientific Reports (Nature) USA, 13 July 2016

Oncology

Key words: Biomedical materials, cancer imaging, hepatic artery, nanotechnology in cancer, targeted therapies [more]

Quantitative comparison and reproducibility of pathologist scoring and digital image analysis of estrogen receptor β2 immunohistochemistry in prostate cancer

Anthony E Rizzardi, Xiaotun Zhang, Rachel Isaksson Vogel, Suzanne Kolb, Milan S Geybels, Yuet-Kin Leung, Jonathan C Henriksen, Shuk-Mei Ho, Julianna Kwak, Janet L Stanford, and Stephen C Schmechel

Diagnostic Pathology (BioMed Central) USA, 11 July 2016

Pathology

Key words: Prostate cancer, Biomarkers, Digital pathology, Quantification, Estrogen receptor β2 [more]

Induction of Suppressor Cells and Increased Tumor Growth following Chronic Psychosocial Stress in Male Mice

Dominic Schmidt, Daniel Peterlik, Stefan O Reber, Anja Lechner, Daniela N Männel

PLoS One (PLOS) Germany, 08 July 2016

Neuroscience

Key words: Chronic subordinate colony, myeloid cells, hypothalamus-pituitary-adrenal, sympathetic nervous system [more]

Lesional CD4+ IFN-γ+ cytotoxic T lymphocytes in IgG4-related dacryoadenitis and sialoadenitis

Takashi Maehara, Hamid Mattoo, Miho Ohta, Vinay S Mahajan, Masafumi Moriyama, Masaki Yamauchi, Jefte Drijvers, Seiji Nakamura, John H Stone, Shiv S Pillai

Annals of the Rheumatic Diseases (BMJ Journals) Japan, 29 June 2016

Rheumatology

Key words: IgG4-related disease, T lymphocytes, Sjögren's syndrome, [more]

Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma

Hweixian Leong Penny, Je Lin Sieow, Giulia Adriani, Wei Hseun Yeap, Peter See Chi Ee, Boris San Luis, Bernett Lee, Terence Lee, Shi Ya Mak, Ying Swan Ho, Choon Kiat Ong, Ruby Y J Huang, Florent Ginhoux, Olaf Rotzschke, Roger D Kamm and Siew, Cheng Wong

OncoImmunology (Taylor and Francis) Singapore, 21 June 2016

Oncology

Key words: Metabolism, macrophages, pancreatic cancer, metastasis [more]

ICAM-1 Binding Rhinoviruses A89 and B14 Uncoat in Different Endosomal Compartments

Rick Conzemius, Haleh Ganjian, Dieter Blaas and Renate Fuchs

Journal of Virology (American Society for Microbiology) Austria, 20 June 2016

Virology

Key words: Human rhinovirus A89 (HRV-A89) and HRV-B14, RNA genome, endocytic recycling compartment (ERC) [more]

Validation of tumor protein marker quantification by two independent automated immunofluorescence image analysis platforms

Amy R Peck, Melanie A Girondo, Chengbao Liu, Albert J Kovatich, Jeffrey A Hooke, Craig D Shriver, Hai Hu, Edith P Mitchell, Boris Freydin, Terry Hyslop, Inna Chervoneva and Hallgeir Rui

Modern Pathology (Nature) USA, 17 June 2016

Medical Image Analysis

Key words: Histology, biomarkers, breast tumor

Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells

Chen-Chi Liu, Shih-Pei Lin, Han-Shui Hsu, Shung-Haur Yang, Chiu-Hua Lin, Muh-Hwa Yang, Mien-Chie Hung and Shih-Chieh Hung

Nature Communications (Nature) Taiwan, 16 June 2016

Oncology

Key words: Biological sciences, cancer, cell biology [more]

A new fluorescence/PET probe for targeting intracellular human telomerase reverse transcriptase (hTERT) using Tat peptide-conjugated IgM

Kyung oh Jung, Hyewon Youn, Seung Hoo Kim, Young-Hwa Kim, Keon Wook Kang, June-Key Chunga

Biochemical and Biophysical Research Communications (Elsevier) South Korea, 15 June 2016

Biological Methods

Key words: Intracellular and intranuclear protein, hTERT, tat peptide, IgM antibody, 64Cu, Live cell imaging [more]

Ribosome inactivation leads to attenuation of intestinal polymeric Ig receptor expression via differential regulation of human antigen R

KH Do, SH Park, J Kim, M Yu, Y Moon

The Journal of Immunology (American Association of Immunologists) South Korea, 15 June 2016

Immunology

Key words: Ribosome, Polymeric Ig Receptor, Differential Regulation, Human Antigen R [more]

Development of a novel mouse model of hepatocellular carcinoma with nonalcoholic steatohepatitis using a high-fat, choline-deficient diet and intraperitoneal injection of diethylnitrosamine

Norihiro Kishida, Sachiko Matsuda, Osamu ItanoEmail author, Masahiro Shinoda, Minoru Kitago,Hiroshi Yagi, Yuta Abe, Taizo Hibi, Yohei Masugi, Koichi Aiura, Michiie Sakamoto and Yuko Kitagawa

BMC Gastroenterology (BioMed Central) Japan, 13 June 2016

Oncology

Key words: Nonalcoholic steatohepatitis, hepatocellular carcinoma, diethylnitrosamine, high-fat choline-deficient diet, mouse model [more]

Automated muscle fiber type population analysis with ImageJ of whole rat muscles using rapid myosin heavy chain immunohistochemistry

Konstantin D Bergmeister, Marion Gröger, Martin Aman, Anna Willensdorfer, Krisztina Manzano-Szalai, Stefan Salminger and Oskar C Aszmann

Muscle and Nerve (Wiley) Austria, 13 June 2016

Medical Image Analysis

Key words: Automated muscle fiber analysis, fiber population, ImageJ, muscle fiber type, myosin heavy chain, rat [more]

Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation

Pu-Hyeon Cha, Yong-Hee Cho, Sang-Kyu Lee, JaeHeon Lee, Woo-Jeong Jeong, Byoung-San Moon, Ji-Hye Yun, Jee Sun Yang, Sooho Choi, Juyong Yoon, Hyun-Yi Kim, Mi-Yeon Kim, Saluja Kaduwal, Weontae Lee, Do Sik Min, Hoguen Kim, Gyoonhee Han and Kang-Yell Choi

Nature Chemical Biology (Nature) South Korea, 13 June 2016

Oncology

Key words: Cancer therapy, cell signalling, screening, small molecules [more]

Clonorchis sinensis omega-class glutathione transferases play major roles in the protection of the reproductive system during maturation and the response to oxidative stress

Jeong-Geun Kim, Chun-Seob Ahn, Seon-Hee Kim, Young-An Bae, Na-Young Kwon, Insug Kang, Hyun-Jong Yang, Woon-Mok Sohn, Yoon Kong

Parasites and Vectors (BioMed Central) South Korea, 13 June 2016

Parasitology

Key words: Clonorchis sinensis, glutathione transferase (GST), omega-class GST, sexual maturation, reproductive system, oxidative stress [more]

Amniotic Fluid Cells Proliferation in Normal and Down Syndrome Subjects

A Honcea, R Iulian, AG Pavel, I Ion, LE Sima

ARS Medica Tomitana (Sciendo) Romania, 11 June 2016

Reproductive Medicine

Key words: Down syndrome, Trisomy 21, amniotic fluid-derived stem cells, proliferation, cell cycle [more]

Epidermal desmoglein 1 expression is reduced in kidney transplant recipients compared to immunocompetent patients

Jodi L Johnson, Paul Hoover, Borko D Jovanovic, Kathleen J Green, John J Friedewald, June K Robinson

Journal of Investigative Dermatology (Elsevier) USA, 11 June 2016

Dermatology

Key words: Calcineurin inhibitor, desmoglein, E-cadherin, epidermal growth factor receptor, histone deacetylase inhibitor, immunocompetent patient, K1/10, Keratin 1 or 10, kidney transplant recipient, mycophenolate mofitil, plakoglobin, squamous cell carcinoma, ultraviolet light [more]

ApoE deficiency exacerbates the development and sustainment of a semi-chronic K/BxN serum transfer-induced arthritis model

Amy M Archer, Rana Saber, Shawn Rose, Alexander Shaffer, Alexander V Misharin, FuNien Tsai, G Kenneth Haines III, Salina Dominguez, Mesut Eren, Douglas E Vaughan, Carla M Cuda and Harris Perlman

Journal of Translational Medicine (BioMed Central) USA, 10 June 2016

Immunology

Key words: Arthritis, cholesterol, inflammation, animal models of human disease [more]

Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells in vitro and in an orthotopic mouse model

Hui-Wen Chiu, Ya-Ling Yeh, Yi-Ching Wang, Wei-Jan Huang, Sheng-Yow Ho, Pinpin Lin, Ying-Jan Wang

Molecular Cancer (Springer) Taiwan, 10 June 2016

Oncology

Key words: Histone deacetylase inhibitor, radiation, triple-negative breast cancer, autophagy [more]

Infiltration of Macrophages Correlates with Severity of Allograft Rejection and Outcome in Human Kidney Transplantation

Tobias Bergler, Bettina Jung, Felix Bourier, Louisa Kühne, Miriam C Banas, Petra Rümmele, Simone Wurm, Bernhard Banas

PLoS One (PLOS) Germany, 10 June 2016

Transplantation Medicine

Key words: Macropaghes, T-lymphocytes, calcineriurin, inhibitor, renal transplantation [more]

Gain of BDNF Function in Engrafted Neural Stem Cells Promotes the Therapeutic Potential for Alzheimer's Disease

Cheng-Chun Wu, Cheng-Chang Lien, Wen-Hsien Hou, Po-Min Chiang,Kuen-Jer Tsai

Scientific Reports (Nature) Taiwan, 06 June 2016

Neuroscience

Key words: Dementia, neural stem cells, regeneration and repair in the nervous system, stem-cell research [more]

Non-invasive, neuron-specific gene therapy by focused ultrasound-induced blood-brain barrier opening in Parkinson's disease mouse model

CY Lin, HY Hsieh, CM Chen, SR Wu, CH Tsai, CY Huang, MY Hua, CK Yeh, HL Liu

Journal of Controlled Release (Elsevier) Taiwan, 26 May 2016

Neuroscience

Key words: Focused ultrasound, Gene therapy, Blood-brain barrier opening, Microbubbles, GDNF [more]

Functional studies on primary tubular epithelial cells indicate a tumor suppressor role of SETD2 in clear cell renal cell carcinoma

J Li, J Kluiver, J Osinga, H Westers, MB van Werkhoven, Marc A Seelen, Rolf H Sijmons, Ankevan den Berg, Klaas Kok

Neoplasia (Elsevier) The Netherlands, 26 May 2016

Oncology

Key words: Primary Tubular Epithelial Cells, Tumor Suppression, SETD2, Renal Cell Carcinoma [more]

GBIQ: a non-arbitrary, non-biased method for quantification of fluorescent images

Youichirou Ninomiya, Wei Zhao,Yumiko Saga

Scientific Reports (Nature) Japan, 23 May 2016

Medical Image Analysis

Key words: Image processing, software [more]

The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas

Daniela F Quail, Robert L Bowman, Leila Akkari, Marsha L Quick, Alberto J Schuhmacher, Jason T Huse, Eric C Holland, James C Sutton, Johanna A Joyce

Science (American Association for the Advancement of Science) USA, 20 May 2016

Oncology

Key words: Mouse models, glioblastoma multiforme, macrophage [more]

Knockout of ho-1 protects the striatum from ferrous iron-induced injury in a male-specific manner in mice

Li-Fang Wang, Kazunari K Yokoyama, Chih-Lung Lin, Tzu-Yin Chen, Hsiu-Wen Hsiao, Pei-Chi Chiang, Chin Hsu

Scientific Reports (Nature) Taiwan, 20 May 2016

Neuroscience

Key words: Neuronal physiology, reproductive biology [more]

Anti-TGF-β Antibody, 1D11, Ameliorates Glomerular Fibrosis in Mouse Models after the Onset of Proteinuria

Xiaoyan Liang, H William Schnaper, Taiji Matsusaka, Ira Pastan, Steve Ledbetter,Tomoko Hayashida

PLoS One (PLOS) USA, 17 May 2016

Nephrology

Key words: Renal fibrosis [more]

HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity

Niek GJ Leusa, Petra E van der Woudena, Thea van den Boscha, Wouter TR Hooghiemstraa, Maria E Ourailidoua, Loes EM Kistemakerc, Rainer Bischoffb, Reinoud Gosensc, Hidde J Haismaa, Frank J Dekker

Biochemical Pharmacology (Elsevier) The Netherlands, 15 May 2016

Pharmacology

Key words: Lysine acetylation, HDACs, inflammation, NF-κB p65, HDAC inhibitors, lung disease [more]

Exploration of more effective neurorrhaphy in facial nerve reconstruction: A comparison focusing on the difference of neural window size and condition of the neurorrhaphy site

Kentaro Ono, Yuhei Yamamoto, Ryuji Shichinohe, Naoki Murao, Akihiko Oyama, Emi Funayama, Hiroshi Furukawa

Journal of Plastic, Reconstructive and Aesthetic Surgery (Elsevier) Japan, 12 May 2016

Neuroscience

Key words: Nerve reconstruction, Facial palsy, Side to side, End to side, Rat [more]

The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth

Harini Nivarthi, Claire Gordziel, Madeleine Themanns, Nina Kramer, Markus Eberl, Björn Rabe, Michaela Schlederer, Stefan Rose-John, Thomas Knösel, Lukas Kenner, Patricia Freund, Fritz Aberger, Xiaonan Han, Robert Kralovics, Helmut Dolznig, Susanne Jennek, Karlheinz Friedrich, and Richard Moriggl

Oncotarget (Impact Journals) Austria, germany, USA, 12 May 2016

Oncology

Key words: STAT1, STAT3, colorectal cancer [more]

MAL Is a Regulator of the Recruitment of Myelin Protein PLP to Membrane Microdomains

Marjolein Bijlard, Jenny C de Jonge, Bert Klunder, Anita Nomden, Dick Hoekstra, Wia Baron

PLoS One (PLOS) The Netherlands, 12 May 2016

Neuroscience

Key words: Oligodendrocytes, myelin membrane, rat brain tissue [more]

In situ hybridization to detect and localize signature cytokines of T-helper (Th) 1 and Th2 immune responses in chicken tissues

Fana Alem Kidane, Ivana Bilic, Taniya Mitra, Patricia Wernsdorf, Michael Hess, Dieter Liebhart

Veterinary Immunology and Immunopathology (Elsevier) Austria, 12 May 2016

Immunology

Key words: In situ hybridization, RNA probes, ChIFN-γ, ChIL-4, ChIL-13 [more]

Acidic pH-triggered drug-eluting nanocomposites for magnetic resonance imaging-monitored intra-arterial drug delivery to hepatocellular carcinoma

W Park, J Chen, S Cho, S Park, AC Larson, K Na, DH Kim

Applied Materials and Interfaces (ACS Publications) USA, South Korea, 09 May 2016

Nanomedicine, Oncology

Key words: hepatocellular carcinoma, image-guided therapy, iron oxide nanoparticles, nanocomposite microspheres, pH-responsive materials, sorafenib [more]

Interleukin-25 is detrimental for recovery after spinal cord injury in mice

Dearbhaile Dooley, Evi Lemmens, Peter Ponsaerts, Sven Hendrix

Journal of Neuroinflammation (Springer) Belgium, 06 May 2016

Neuroscience

Key words: IL-25, type 2 immune response, spinal cord injury, basso mouse scale, locomotor recovery Th1 Th2 [more]

CCR6 expression in colon cancer is associated with advanced disease and supports epithelial-to-mesenchymal transition

Neeraj Kapur, Hina Mir, Clarence E Clark III, Uma Krishnamurti, Derrick J Beech, James W Lillard and Shailesh Singh

British Journal of Cancer (Nature) USA, 05 May 2016

Oncology

Key words: Colon cancer, Epithelial–mesenchymal transition, Metastasis, Tumour biomarkers [more]

PPARγ inhibits VSMC proliferation and migration via attenuating oxidative stress through upregulating UCP2

Y Zhou, MJ Zhang, BH Li, L Chen, Y Pi, YW Yin, CY Long, X Wang, MJ Sun, X Chen, CY Gao, JC Li, LL Zhang

PLoS One (PLOS) China, 04 May 2016

Cell Biology

Key words: Oxidative stress, Reactive oxygen species, Carotid arteries, Mitochondria, Antioxidants, MTT assay, Fluorescence microscopy, Growth factors [more]

Loss of HIF-1β in macrophages attenuates AhR/ARNT-mediated tumorigenesis in a PAH-driven tumor model

Nina Henke, Nerea Ferreirós, Gerd Geisslinger, Martina G Ding, Silke Essler, Dominik C Fuhrmann, Theresa Geis, Dmitry Namgaladze, Nathalie Dehne, and Bernhard Brüne

Oncotarget (Impact Journals) Germany, 03 May 2016

Oncology

Key words: xenobiotics, CYP1A1, DNA damage, breast cancer, fibrosarcoma [more]

449 In situ mapping of innate lymphoid cells in normal and inflamed human skin

M Brüggen, W Bauer, B Reininger, E Clim, C Captarencu, B Meier, PM Brunner, L French, G Stingl

Journal of Investigative Dermatology (Elsevier) Austria, 01 May 2016

Immunology

Key words: Innate lymphoid cells, atopic dermatitis, psoriasis, normal human skin, immunofluorescence [more]

Paracrine Factors from Irradiated Peripheral Blood Mononuclear Cells Improve Skin Regeneration and Angiogenesis in a Porcine Burn Model

Stefan Hacker, Rainer Mittermayr, Stefanie Nickl, Thomas Haider, Diana Lebherz-Eichinger, Lucian Beer, Andreas Mitterbauer, Harald Leiss, Matthias Zimmermann, Thomas Schweiger, Claudia Keibl, Helmut Hofbauer, Christian Gabriel, Mariann Pavone-Gyöngyösi, Heinz Redl, Erwin Tschachler, Michael Mildner, Hendrik Jan Ankersmit

Scientific Reports (Nature) Austria, 29 April 2016

Regenerative Medicine

Key words: Drug development, regeneration, translational research, trauma [more]

SIRT2-mediated deacetylation and tetramerization of pyruvate kinase directs glycolysis and tumor growth

David Gius

Cancer Research (AACR Publications) USA, 27 April 2016

Oncology

Key words: Mitochondria, pyruvate kinase, acetylation, mammary tumor cells [more]

Benzyl butyl phthalate promotes breast cancer stem cell expansion via SPHK1/S1P/S1PR3 signaling

Yu-Chih Wang, Cheng-Fang Tsai, Hsiao-Li Chuang, Yi-Chih Chang, Hung-Sheng Chen, Jau-Nan Lee, and Eing-Mei Tsai

Oncotarget (Impact Journals) Taiwan, 26 April 2016

Oncology

Key words: Aryl hydrocarbon receptor, sphingosine kinase 1, sphingosine 1-phosphate, sphingosine-1-phosphate receptor 3, breast cancer stem cells [more]

Tumor-associated B cells in cutaneous primary melanoma and improved clinical outcome

Kanika Garg, Margarita Maurer, Johannes Griss, Marie-Charlotte Brüggen, Ingrid H Wolf, Christine Wagnera, Niels Willi, Kirsten D Mertz, Stephan N Wagner

Human Pathology (Elsevier) Austria, 20 April 2016

Pathology

Key words: CD20, prognosis, melanoma, tumor microenvironment, tumor-associated B cells (TAB), tumor-infiltrating lymphocytes [more]

Effectiveness of a Layer-by-Layer Microbubbles-Based Delivery System for Applying Minoxidil to Enhance Hair Growth

Ai-Ho Liao,Ying-Jui Lu, Yi-Chun Lin, Hang-Kang Chen, Huey-Kang Sytwu, Chih-Hung Wang

Theranostics (Ivyspring International Publisher) Taiwan, 11 April 2016

Oncology

Key words: Microbubbles, ultrasound, transdermal drug delivery, minoxidil, chitosan oligosaccharide lactate, hair growth [more]

Biocompatibility Assessment of a New Biodegradable Vascular Graft via In Vitro Co-culture Approaches and In Vivo Model

Marjan Enayati, Magdalena Eilenberg, Christian Grasl, Peter Riedl, Christoph Kaun, Barbara Messner, Ingrid Walter, Robert Liska, Heinrich Schima, Johann Wojta, Bruno K Podesser, Helga Bergmeister

Annals of Biomedical Engineering (Springer) Austria, 07 April 2016

Regenerative Medicine

Key words: Vascular graft, biocompatibility, biodegradable polyurethane, fibroblast-macrophage co-culture [more]

Dose-escalation study for the targeting of CD44v+cancer stem cells by sulfasalazine in patients with advanced gastric cancer (EPOC1205)

Kohei Shitara, Toshihiko Doi, Osamu Nagano, Chiyo K Imamura, Takeshi Ozeki, Yuya Ishii, Kenji Tsuchihashi, Shunji Takahashi, Takako E Nakajima, Shuichi Hironaka, Miki Fukutani, Hiromi Hasegawa, Shogo Nomura, Akihiro Sato, Yasuaki Einaga, Takeshi Kuwata, Hideyuki Saya, Atsushi Ohtsu

Gastric Cancer (Springer) Japan, 07 April 2016

Oncology

Key words: Cancer stem cellCD44 variant positiveGastric cancerSulfasalazinexCT [more]

Oxidative phosphorylation and mitochondrial function differ between human prostate tissue and cultured cells

Bernd Schöpf, Georg Schäfer, Anja Weber, Heribert Talasz,Iris E Eder, Helmut Klocker, Erich Gnaiger

FEBS Journal (FEBS PRESS) Austria, 06 April 2016

Cell Biology

Key words: electron transfer system, high‐resolution respirometry, mitochondria, oxidative phosphorylation, prostate metabolism [more]

Cross-talk between DopaChromeTautomerase and Caveolin-1 is melanoma cell phenotype specific and potentially involved in tumor progression.

Popa IL, Milac AL, Sima LE, Alexandru PR, Pastrama F, Munteanu CV, Negroiu Gabriela

Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) Romania, 06 April 2016

Oncology

Key words: Antigen processing, caveolin, epithelial-mesenchymal transition (EMT), melanoma, structural model [more]

Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival

Jonas Kloeppera,Lars Riedemanna, Zohreh Amoozgara,1, Giorgio Seanoa, Katharina Suseka, Veronica Yua, Nisha Dalviea, Robin L Amelunga, Meenal Dattaa,Jonathan W Songa,Vasileios Askoxylakisa, Jennie W Taylora,Christine Lu-Emersona,Ana Batistaa,Nathaniel D Kirkpatricka,Keehoon Junga, Matija Snuderla, Alona Muzikanskye, Kay G Stubenrauchf, Oliver Krieterf, Hiroaki Wakimotog, Lei Xu1, Lance L Munna, Dan G Dudaa, Dai Fukumuraa, Tracy T Batchelorc, Rakesh K Jaina,

PNAS (PNAS) USA, 04 April 2016

Oncology

Key words: Anti-angiogenic therapy, tumor microenvironment, anti-tumor immunity, macrophage polarization, microglia reprogramming [more]

CD103 defines intraepithelial CD8+ PD1+ tumour-infiltrating lymphocytes of prognostic significance in endometrial adenocarcinoma

Hagma H Workel, Fenne L Komdeur, Maartje CA Wouters, Annechien Plat, Harry G Klip, Florine A Eggink, G Bea A Wisman, Henriette JG Arts, Maaike HM Oonk, Marian JE Mourits, Refika Yigit, Marco Versluis, Evelien W Duiker, Harry Hollema, Marco de Bruyn, Hans W Nijman

European Journal of Cancer (Elsevier) The Netherlands, 31 March 2016

Oncology

Key words: Tumour-infiltrating lymphocytes, endometrial cancer, adenocarcinoma, CD103, survival [more]

Combining ultrasound and lactobacilli treatment for high-fat-diet-induced obesity in mice

A-H Liao, C-B Jiang, C-C Li, H-C Chuang, J-S Chiang Chiau, W-T Chan, C-Y Yeung, M-L Cheng, H-C Lee

Journal of Animal Physiology and Animal Nutrition (Wiley) Taiwan, 29 March 2016

Physiology

Key words: Actobacilli, ultrasound, high-fat-diet-induced obesity mice, micro-CT, fat deposition [more]

Myeloid PTEN deficiency impairs tumor-immune surveillance via immune-checkpoint inhibition

M Kuttke, E Sahin, J Pisoni, S Percig, A Vogel, D Kraemmer, L Hanzl, J S Brunner, H Paar, K Soukup, A Halfmann, A M Dohnal, C W Steiner, S Blüml, J Basilio, B Hochreiter, M Salzmann, B Hoesel, G Lametschwandtner, R Eferl, J A Schmidd and G Schabbauer

OncoImmunology (Taylor and Francis) Austria, 28 March 2016

Immunology

Key words: Colitis-associated colon cancer, myeloid Pi3K, tumor immune-surveillance [more]

Chemotherapy of Colorectal Liver Metastases Induces a Rapid Rise in Intermediate Blood Monocytes which Predicts Treatment Response

Dominic Schauer, Patrick Starlinger, Lejla Alidzanovic, Philipp Zajc, Thomas Maier, Alexandra Feldman, Robin Padickakudy, Elisabeth Buchberger, Vanessa Elleder, Andreas Spittlera, Judith Stift, Lorand Pop, Birgit Gruenberger, Thomas Gruenbergera, Christine Brostjan

OncoImmunology (Taylor and Francis) Austria, 22 March 2016

Immunology

Key words: Chemotherapy, colorectal liver metastase, blood monocytes [more]

A specific area of olfactory cortex involved in stress hormone responses to predator odours

Kunio Kondoh, Zhonghua Lu, Xiaolan Ye, David P Olson, Bradford B Lowell and Linda B Buck

Nature (Nature) USA, 21 March 2016

Neuroscience

Key words: Neural circuits, Olfactory cortex, Sensory processing [more]

MiRNA-124 induces neuroprotection and functional improvement after focal cerebral ischemia

Somayyeh Hamzei Taj, Widuri Kho, Adrien Riou, Dirk Wiedermann, Mathias Hoehn

Biomaterials (Elsevier) The Netherlands, 19 March 2016

Neuroscience

Key words: MicroRNA-124, ischemic stroke, immune cell modulation/polarization, neuroprotection, functional improvement, arginase-1 [more]

Neuronal deficiency of HIF prolyl 4-hydroxylase 2 in mice improves ischemic stroke recovery in an HIF dependent manner

Lexiao Li, Pamela Saliba, Stefan Reischl, Hugo H Marti, Reiner Kunze

Neurobiology of Disease (Elsevier) Germany, 19 March 2016

Neuroscience

Key words: PHD2, HIF, neuron, focal cerebral ischemia, hypoxia, VEGF, angiogenesis [more]

Unfractionated bone marrow cells attenuate paraquat-induced glomerular injury and acute renal failure by modulating the inflammatory response

SY Gu, TY Yeh, SY Lin, FC Peng

Scientific Reports (Nature) Taiwan, 18 March 2016

Nephrology

Key words: Acute kidney injury, Bone marrow transplantation [more]

High Resolution Ultrasonography for Assessment of Renal Cysts in the PCK Rat Model of Autosomal Recessive Polycystic Kidney Disease

S Kapoor, D Rodriguez, K Mitchell, RP Wüthrich

Kidney and Blood Pressure Research (Karger) Switzerland, 17 March 2016

Nephrology

Key words: High resolution diagnostic imaging, Total cyst volume, Polycystic kidney disease, PCK rat, Total kidney volume [more]

Efficient generation of smooth muscle cells from adipose-derived stromal cells by 3D mechanical stimulation can substitute the use of growth factors in vascular tissue engineering

Mojtaba Parvizi, Lydia AM Bolhuis-Versteeg, Andrá A Poot, Martin C Harmsen

Biotechnology Journal (Wiley) The Netherlands, 15 March 2016

Regenerative Medicine

Key words: Adipose tissue-derived stromal cells (ASC), poly(1, 3-trimethylene carbonate) (PTMC), smooth muscle cells (SMC), transforming Growth Factor beta 1 (TGF-ß1), vascular tissue engineering [more]

OX40 ligand newly expressed on bronchiolar progenitors mediates influenza infection and further exacerbates pneumonia

Taizou Hirano, Toshiaki Kikuchi, Naoki Tode, Arif Santoso, Mitsuhiro Yamada, Yoshiya Mitsuhashi, Riyo Komatsu, Takeshi Kawabe, Takeshi Tanimoto, Naoto Ishii, Yuetsu Tanaka, Hidekazu Nishimura, Toshihiro Nukiwa, Akira Watanabe, Masakazu Ichinose

EMBO Molecular Medicine (EMBO press) Japan, 14 March 2016

Pathology

Key words: Bronchioles, glycosylation regeneration, OX40 ligand, viral pneumonia [more]

Internalization of nanopolymeric tracers does not alter characteristics of placental cells

Paolo Bigini, Elisa R Zanier, Silvia Saragozza, Simona Maciotta, Pietro Romele, Patrizia Bonassi Signoroni, Antonietta Silini, Francesca Pischiutta, Eliana Sammali, Claudia Balducci, Martina B Violatto, Laura Talamini, David Garry, Davide Moscatelli, Raffaele Ferrari, Mario Salmona, Maria Grazia De Simoni, Federico Maggi, Giuseppe Simoni, Francesca Romana Grati, Ornella Parolini

Journal of Cellular and Molecular Medicine (Wiley) Italy, 14 March 2016

Cell Biology

Key words: Cell tracing, nanoparticles, mesenchymal stem/stromal cells, placenta, amnion, chorion, hypoxia, ischaemia [more]

In primary Sjögren's syndrome high absolute numbers and proportions of B cells in parotid glands predict responsiveness to rituximab as defined by ESSDAI, but not by SSRI

Konstantina Delli, Erlin A Haacke, Frans GM Kroese, Rodney P Pollard, Stephan Ihrler, Bert van der Vegt, Arjan Vissink, Hendrika Bootsma, Frederik KL Spijkervet

Annals of the Rheumatic Diseases (BMJ Journals) The Netherlands, 09 March 2016

Rheumatology

Key words: Sjogren's syndrome, b cells, parotide glands, rituximab [more]

Acquisition of chemoresistance and other malignancy-related features of colorectal cancer cells are incremented by ribosome-inactivating stress

CK Oh, SJ Lee, SH Park, Y Moon

Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) South Korea, 09 March 2016

Oncology

Key words: Ribosome-inactivating stress (RIS), Colorectal cancer, Activating transcription factor 3 (ATF3), Macrophage inhibitory cytokine-1 (MIC-1), Chemosensitivity [more]

Exploring the role of sphingolipid machinery during the epithelial to mesenchymal transition program using an integrative approach

Anastasia Meshcheryakova, Martin Svoboda, Ammar Tahir, Harald C Köfeler, Alexander Triebl, Felicitas Mungenast, Georg Heinze, Christopher Gerner, Philip Zimmermann, Markus Jaritz, and Diana Mechtcheriakova

Oncotarget (Impact Journals) Austria, Switzerland, 07 March 2016

Oncology

Key words: sphingolipid-related targets, sphingosine 1-phosphate/ceramide rheostat, multigene signature, epithelial to mesenchymal transition, lung cancer [more]

Intrathecal transplantation of embryonic stem cell-derived spinal GABAergic neural precursor cells attenuates neuropathic pain in a spinal cord injury rat model

Insik Hwang, Suk-Chan Hahm Suk-Chan Hahm, Kyung-Ah Choi, Sung-Ho Park, Hyesun Jeong, Ji-Hye Yea, Junesun Kim, PhD, Sunghoi Hong, PhD

Cell Transplantation (SAGE Journals) South Korea, 01 March 2016

Regenerative Medicine

Key words: Spinal cord injury (SCI), Neuropathic pain, Spinal GABAergic neurons, Intrathecal transplantation [more]

Platelet-rich plasma influences expansion and paracrine function of adipose-derived stromal cells in a dose-dependent fashion

Willemsen, Joep C N, Spiekman, Maroesjka, Stevens, H P Jeroen, van der Lei, Berend, Harmsen, Martin C

Plastic and Reconstructive Surgery (Ingentaconnect) The Netherlands, 01 March 2016

Regenerative Medicine

[more]

Double Linear Gradient Biointerfaces for Determining Two-Parameter Dependent Stem Cell Behavior

Patrick Van Rijn, Philipp Kuhn, Qihui Zhou, Torben Van Der Boon, Aneta Schaap-Oziemlak, Theo Van Kooten

ChemNanoMat (Wiley) The Netherlands, 26 February 2016

Biological Methods

Key words: Biointerfaces, gradients, stem cell, wettability, stiffness [more]

Fenretinide: a potential treatment for endometriosis

Mary Ellen Pavone, Saurabh S Malpani, Matthew Dyson, J Julie Kim, Serdar E Bulun

Reproductive Sciences (SAGE Journals) USA, 25 February 2016

Reproductive Medicine

Key words: endometriosis, fenretinide, apoptosis, retinol, retinoid, STRA6, retinoic acid [more]

Cooperation of ETV6/RUNX1 and BCL2 enhances immunoglobulin production and accelerates glomerulonephritis in transgenic mice

Eva Bauer, Michaela Schlederer, Ruth Scheicher, Jaqueline Horvath, Petra Aigner, Ana-Iris Schiefer, Renate Kain, Heinz Regele, Gregor Hoermann, Günter Steiner, Lukas Kenner, Veronika Sexl, Andreas Villunger, Richard Moriggl, and Dagmar Stoiber

Oncotarget (Impact Journals) Austria, 23 February 2016

Oncology

Key words: ETV6/RUNX1, BCL2, glomerulonephritis, lymphoma, autoimmunity, Immunology and Microbiology Section, Immune response, Immunity [more]

In situ analysis of intrahepatic virological events in chronic hepatitis B virus infection

Xiaonan Zhang, Wei Lu, Ye Zheng, Weixia Wang, Lu Bai, Liang Chen, Yanling Feng, Zhanqing Zhang, and Zhenghong Yuan

The Journal of Clinical Investigation (American Society for Clinical Investigation) China, 22 February 2016

Virology

Key words: intrahepatic virological events, chronic hepatitis B virus infection [more]

In EXOG-depleted cardiomyocytes cell death is marked by a decreased mitochondrial reserve capacity of the electron transport chain

Wardit Tigchelaar, Anne Margreet De Jong, Wiek H van Gilst, Rudolf A De Boer, Herman HW Silljé

Inside the Cell (Wiley) The Netherlands, 18 February 2016

Cell Biology

Key words: Cardiomyocyte, cell death, EXOG, hypertrophy, mitochondria [more]

Fc receptor-mediated phagocytosis in tissues as a potent mechanism for preventive and therapeutic HIV vaccine strategies

M Sips, M Krykbaeva, T J Diefenbach, M Ghebremichael, B A Bowman, A-S Dugast, A W Boesch, H Streeck, D S Kwon, M E Ackerman, T J Suscovich, P Brouckaert, T W Schacker and G Alter

Mucosal Immunology (Nature) USA, Belgium, Germany, 17 February 2016

Key words: Cell signalling, HIV infections, Phagocytosis, Vaccines [more]

Aging has small effects on initial ischemic acute kidney injury development despite changing intrarenal immunologic micromilieu in mice

Hye Ryoun Jang, Ji Hyeon Park, Ghee Young Kwon, Jae Berm Park, Jung Eun Lee, Dae Joong Kim, Yoon-Goo Kim, Sung Joo Kim, Ha Young Oh, Wooseong Huh

American Journal of Physiology (APS Journals) South Korea, 15 February 2016

Physiology

Key words: Aging, ischemic, kidney injury, immunologic, micromilieu [more]

The in vitro response of tissue stem cells to irradiation with different LETs

Peter W Nagle, Nynke A Hosper, Emily M Ploeg, Marc-Jan van Goethem, Sytze Brandenburg, Johannes A Langendijk, Roland K Chiu, Robert P Coppes

International Journal of Radiation Oncology (Elsevier) The Netherlands, 12 February 2016

Oncology

Key words: In vitro, tissue stem cells, irradiantion, LETs [more]

Far-infrared promotes burn wound healing by suppressing NLRP3 inflammasome caused by enhanced autophagy

Hui-Wen Chiu, Cheng-Hsien Chen, Jen-Ning Chang, Chien-Hsiung Chen, Yung-Ho Hsu

Journal of Molecular Medicine (Springer) Taiwan, 11 February 2016

Regenerative Medicine

Key words: Far-infrared, burn wound healing, autophagy NLRP3 inflammasome [more]

Serum Autoantibodies in Chronic Prostate Inflammation in Prostate Cancer Patients

Bettina Schlick, Petra Massoner, Angelika Lueking, Pornpimol Charoentong, Mirjam Blattner, Georg Schaefer, Klaus Marquart, Carmen Theek, Peter Amersdorfer, Dirk Zielinski, Matthias Kirchner, Zlatko Trajanoski, Mark A Rubin, Stefan Müllner, Peter Schulz-Knappe, Helmut Klocker

PLoS One (PLOS) Austria, 10 February 2016

Oncology

Key words: Prostate cancer, autoantibodies, inflammation, prostate gland, inflammatory diseases, microarrays, prostate diseases, radical prostatectomy [more]

Acquisition of tumorigenic potential and enhancement of angiogenesis in pulmonary stem/progenitor cells through Oct-4 hyperexpression

SY Gu, CC Ho, YK Huang, HW Chen, YC Wang, CY Kuo, SC Teng, WM Fu, PC Yang, CW Wu, FC Peng, TY Ling

Oncotarget (Impact Journals) Taiwan, 09 February 2016

Oncology

Key words: pulmonary stem/progenitor cells, cancer initiating cells, Oct-4, angiogenesis, angiopoietins/Tie2 [more]

MINI ORAL SESSIONS (MINI38.12 Multiplex Immunofluorescence Identifies Differences in Immune Microenvironment and Prognostic Biomarkers between Mesothelioma Subtypes)

Tanguy Seiwert, Stephanie Mcgregor, Chengyi Shu, Igor Feldman, Tong Zi, Zhixiang Zuo, Arun Khattri, Aliya Husain, Hadi Duraid, Wickii T Vigneswaran,Thomas N Krausz, Sriram Sathyanarayanan, Hedy Lee Kindle

Journal of Thoracic Oncology (Elsevier) USA, 05 February 2016

Oncology

Key words: Multiplex immunofluorescence, immmune microenvironment, biomarkers, mesothelioma [more]

Oxytocin promotes functional coupling between paraventricular nucleus and both sympathetic and parasympathetic cardioregulatory nuclei

Jason R Yee, William M Kenkel, Jessie L Frijling, Sonam Dodhia, Kenneth G Onishi, Santiago Tovar, Maha J Saber, Gregory F Lewis, Wensheng Liu, Stephen W Porges C Sue Carter

Hormones and Behavior (Elsevier) USA, 04 February 2016

Endocrinology

Key words: Oxytocin, functional coupling, paraventricular nucleus, cardioregulatory nuclei [more]

Characterizing Villitis of Unknown Etiology and Inflammation in Stillbirth

Hayley Derricott, Rebecca L Jones, Susan L Greenwood, Gauri Batra, Margaret J Evans, Alexander EP Heazell

The American Journal of Pathology (Elsevier) UK, 03 February 2016

Reproductive Medicine

Key words: Villitis, inflammation, stillbirth [more]

Prevention of SHIV transmission by topical IFN-β treatment

RS Veazey, HA Pilch-Cooper, TJ Hope, G Alter, AM Carias, M Sips, X Wang, B Rodriguez, SF Sieg, A Reich, P Wilkinson, MJ Cameron and MM Lederman

Mucosal Immunology (Nature) USA, 03 February 2016

Virology

Key words: Drug therapy, HIV infections, Mucosal immunology, Viral transmission [more]

Treatment Regimen, Surgical Outcome, and T-cell Differentiation Influence Prognostic Benefit of Tumor-Infiltrating Lymphocytes in High-Grade Serous Ovarian Cancer

Maartje CA Wouters, Fenne L Komdeur1, Hagma H Workel, Harry G Klip, Annechien Plat, Neeltje M Kooi, G Bea A Wisman, Marian JE Mourits, Henriette JG Arts, Maaike HM Oonk, Refika Yigit, Steven de Jong, Cornelis JM Melief, Harry Hollema, Evelien W Duiker, Toos Daemen, Marco de Bruyn, Hans W Nijman

Clinical Cancer Research (High Wire) The Netherlands, 01 February 2016

Oncology

Key words: T-cell diferentiation, tumor-infiltrating lymphocytes, serous ovarian cancer [more]

FGF2 inhibits endothelial–mesenchymal transition through microRNA-20a-mediated repression of canonical TGF-ß signaling

Ana C P Correia, Jan-Renier A J Moonen, Marja G L Brinker, Guido Krenning

Journal of Cell Science (The Company of Biologists) The Netherlands, 01 February 2016

Cell Biology

Key words: Endothelial–mesenchymal transition, microRNA-20a-mediated repression, canonical TGF-β signaling [more]

Infiltration of lymphocyte subpopulations into cancer microtissues as a tool for the exploration of immunomodulatory agents and biomarkers

Stefan Koeck, Marit Zwierzina, Julia M Huber, Mario Bitsche, Edith Lorenz, Gabriele Gamerith, Jozsef Dudas, Jens M Kelm, Heinz Zwierzina, Arno Amann

Immunobiology (Elsevier) Austria, Switzerland, 01 February 2016

Immunology

Key words: 3D, biomarker, co-culture, cancer, immune cells, infiltration, subpopulation [more]

Injectable extracellular matrix hydrogels as scaffolds for spinal cord injury repair

Dmitry Tukmachev, Serhiy Forostyak, Zuzana Koci, Kristyna Zaviskova, Irena Vackova, Karel Vyborny, Ioanna Sandvig, Axel Sandvig, Christopher J Medberry, Stephen F Badylak, Eva Sykova, and Sarka Kubinova

Tissue Engineering Part A (Mary Ann Liebert Inc.) Czech Republic, Norway, UK, Sweden, USA, 28 January 2016

Regenerative Medicine

Key words: spinal cord injury, hydrogel, extracellular matrix, scaffold, tissue engineering, stem cells [more]

Amelioration of Experimental Autoimmune Arthritis Through Targeting of Synovial Fibroblasts by Intraarticular Delivery of MicroRNAs 140-3p and 140-5p

Jia-Shiou Peng, Shih-Yao Chen, Chao-Liang Wu, Hao-Earn Chong, Yun-Chiao Ding, Ai-Li Shiau, Chrong-Reen Wang

Arthritis & Rheumatology (Wiley) Taiwan, 25 January 2016

Rheumatology

Key words: Autoimmune arthritis, synovial fibroblasts, MicroRNAs [more]

Fumaric acid esters promote neuronal survival upon ischemic stress through activation of the Nrf2 but not HIF-1 signaling pathway

Jiemeng Lin-Holderer, Lexiao Li, Daniel Gruneberg, Hugo H Marti, Reiner Kunze

Neuropharmacology (Elsevier) Germany, 19 January 2016

Neuroscience

Key words: Dimethyl fumarate, monomethyl fumarate, fumaric acid esters, Nrf2, HIF, ischemia [more]

Novel technologies and emerging biomarkers for personalized cancer immunotherapy

Jianda Yuan, Priti S Hegde, Raphael Clynes, Periklis G Foukas, Alexandre Harari, Thomas O Kleen, Pia Kvistborg, Cristina Maccalli, Holden T Maecker, David B Page, Harlan Robins, Wenru Song, Edward C Stack, Ena Wang, Theresa L Whiteside, Yingdong Zhao, Heinz Zwierzina, Lisa H Butterfield and Bernard A Fox

Journal for ImmunoTherapy of Cancer (Springer) Qatar, USA, Switzerland, Greece, Germany, The Netherlands, Italy, Austria, 19 January 2016

Oncology

Key words: Immune checkpoint blockade, Cancer immunotherapy, Biomarkers, Task Force, Immune monitoring, Technology, Bioinformatics [more]

Energy landscapes and functions of supramolecular systems

Faifan Tantakitti, Job Boekhoven, Xin Wang, Roman V Kazantsev, Tao Yu, Jiahe Li, Ellen Zhuang, Roya Zandi, Julia H Ortony, Christina J Newcomb, Liam C Palmer, Gajendra S Shekhawat, Monica Olvera de la Cruz, George C Schatz and Samuel I Stupp

Nature Materials (Nature) USA, 18 January 2016

Biomaterials

Key words: Bioinspired materials, Materials science [more]

Software-assisted morphometric and phenotype analyses of human peripheral blood monocyte-derived macrophages induced by a microenvironment model of human esophageal squamous cell carcinoma

Mari Nishio, Naoki Urakawa, Manabu Shigeoka, Nobuhisa Takase, Yumi Ichihara, Noriaki Arai, Yu-ichiro Koma, Hiroshi Yokozaki

Pathology International (Wiley) Japan, 18 January 2016

Pathology

Key words: Esophageal cancer, image analysis, macrophages, tumor microenvironment [more]

Towards personalised treatment in primary Sjögren's syndrome: baseline parotid histopathology predicts responsiveness to rituximab treatment

Konstantina Delli, Erlin A Haacke, Frans G M Kroese, Rodney P Pollard, Stephan Ihrler, Bert van der Vegt, Arjan Vissink, Hendrika Bootsma, Frederik K L Spijkervet

Annals of the Rheumatic Diseases (High Wire) The Netherlands, Germany, 15 January 2016

Rheumatology

Key words: Sjögren's syndrome, parotid histopathology, responsiveness to rituximab treatment [more]

Low birth weight associates with hippocampal gene expression

JP Buschdorf, ML Ong, SX Ong, JL MacIsaac, K Chng, MS Kobor, MJ Meaney, JD Holbrook

Neuroscience (Elsevier) Singapore, Canada, 12 January 2016

Neuroscience

Key words: Low birth weight, hippocampus, DNA methylation, mental disorders, microarray [more]

Inhibition of Aerobic Glycolysis Attenuates Disease Progression in Polycystic Kidney Disease

Meliana Riwanto, Sarika Kapoor, Daniel Rodriguez, Ilka Edenhofer, Stephan Segerer, Rudolf P Wüthrich

PLoS One (PLOS) Switzerland, 11 January 2016

Nephrology

Key words: Kidneys, glycolysis, renal system, epithelial cells, glucose metabolism, apoptosis, ERK signaling cascade, polycystic kidney disease [more]

Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer

Leila Akkari, Vasilena Gocheva, Marsha L Quick, Jemila C Kester, Alison K Spencer, Alfred L Garfall, Robert L Bowman, Johanna A Joyce

Genes and Development (CHS Press) USA, Switzerland, 10 January 2016

Oncology

Key words: Cathepsin protease, compensatory mechanism, cancer [more]

Toll-Like Receptor 4 Is Essential in the Development of Abdominal Aortic Aneurysm

Chao-Han Lai, Kuan-Chieh Wang, Fang-Tzu Lee, Hung-Wen Tsai, Chih-Yuan Ma, Tsung-Lin Cheng, Bi-Ing Chang, Yu-Jen Yang, Guey-Yueh Shi, Hua-Lin Wu

PLoS One (PLOS) Taiwan, 07 January 2016

Immunology

Key words: Macrophages, immune receptor signaling, aneurysms, inflammation, toll-like receptors, aorta, small interfering RNAs, cytokines [more]

The single-chain anti-TNF-a antibody DLX105 induces clinical and biomarker responses upon local administration in patients with chronic plaque-type psoriasis

Athanasios Tsianakas, Patrick M Brunner, Kamran Ghoreschi, Claudia Berger, Karin Loser, Martin Röcken, Georg Stingl, Thomas Luger, Thomas Jung

Experimental Dermatology (Wiley) Germany, Austria, Switzerland, 06 January 2016

Dermatology

Key words: Psoriasis, TNF-alpha, TNF-alpha-blocker [more]

3, 4-Dihydroxy-L-phenylalanine as a novel covalent linker of extracellular matrix proteins to polyacrylamide hydrogels with a tunable stiffness

Olaf Y Wouters, Diana TA Ploeger, Sander M van Putten, and Ruud A Bank

Tissue Engineering Part C (Mary Ann Liebert Inc.) The Netherlands, 05 January 2016

Regenerative Medicine

Key words: Tissue Enigneering, 3, 4-Dihydroxy-L-Phenylalanine, Linker, Extracellular Matrix, Hydrogel, Stiffness [more]

T1 Mapping by CMR Imaging : From Histological Validation to Clinical Implication

Andreas A Kammerlander, Beatrice A Marzluf, Caroline Zotter-Tufaro, Stefan Aschaue, Franz Duca, Alina Bachman, Klaus Knechtelsdorfer, Matthias Wiesinger, Stefan Pfaffenberge, Andreas Greiser Irene M Lang, Diana Bonderman, Julia Mascherbauer

JACC: Cardiovascular Imaging (Elsevier) Austria, Germany, 01 January 2016

Cardiology

Key words: CMR imaging, histological validation [more]

N-octanoyl dopamine attenuates the development of transplant vasculopathy in rat aortic allografts via smooth muscle cell protective mechanisms

J Wedel, MC Hottenrott, M Bulthuis, S Huitema, BA Yard, JK Hillebrands

Transplantation (Wolters Kluwer) The Netherlands, Germany, 01 January 2016

Transplantation Medicine

Key words: N-octanoyl Dopamine, Transplant Vasculopathy, Aortic Allografts, Smooth Muscle Cells, Protective Mechanisms [more]

The anti-inflammatory compound curcumin enhances locomotor and sensory recovery after spinal cord injury in rats by immunomodulation

Lucia Machova Urdzikova, Kristyna Karova, Jiri Ruzicka, Anna Kloudova, Craig Shannon, Jana Dubisova, Raj Murali, Sarka Kubinova, Eva Sykova, Meena Jhanwar-Uniyal and Pavla Jendelova

International Journal of Molecular Sciences (MDPI) Czech Republic, USA, 31 December 2015

Neuroscience

Key words: spinal cord injury, curcumin, inflammation, cytokines, secondary processes, NF-κB [more]

Mercury toxicokinetics of the healthy human term placenta involve amino acid transporters and ABC transporters

Elisabeth Strak, Isabella Ellinger, Christina Balthasar, Matthias Scheinast, Jasmin Schatz, Tamara Szattler, Sonja Bleichert, Leila Saleh, Martin Knöfler, Harald Zeisler, Markus Hengstschläger, Margit Rosner, Hans Salzer, Claudia Gundacker

Toxicology (Elsevier) Austria, 29 December 2015

Toxicology

Key words: Mercury, placenta, amino acid transporters [more]

Long-term in vitro expansion of salivary gland stem cells driven by Wnt signals

Martti Maimets, Cecilia Rocchi, Reinier Bron, Sarah Pringle, Jeroen Kuipers, Ben NG Giepmans, Robert GJ Vries, Hans Clevers, Gerald de Haan, Ronald van Os, Robert P Coppes

Stem Cell Reports (Elsevier) The Netherlands, 24 December 2015

Stem Cell Research

Key words: In Vitro Expansion, Salivary Gland, Stem Cells, Wnt [more]

Long-Term In Vitro Expansion of Salivary Gland Stem Cells Driven by Wnt Signals

Martti Maimets, Cecilia Rocchi, Reinier Bron, Sarah Pringle, Jeroen Kuipers, Ben NG Giepmans, Robert GJ Vries, Hans Clevers, Gerald de Haan, Ronald van Os, Robert P Coppes

Stem Cell Reports (Elsevier) The Netherlands, 24 December 2015

Stem Cell Research

Key words: Stem cells, in vitro expansion, wnt signals [more]

Co-culture of placental explants with isolated CD4 and CD8 T cells: a functional model to define the consequences of placental inflammation

Hayley Derricott, Rebecca L Jones, Alexander EP Heazell, Susan L Greenwood

Journal of Biological Methods (Springer) UK, 22 December 2015

Reproductive Medicine

Key words: inflammation, placenta, T lymphocytes, villitis, VUE [more]

Mycolic acid-specific T cells protect against Mycobacterium tuberculosis infection in a humanized transgenic mouse model

J Zhao, S Siddiqui, S Shang, Y Bian, S Bagchi, Y He, CR Wang

eLife (eLife Sciences Publications) USA, 10 December 2015

Microbiology

Key words: Mycolic acid-specific T cells, Mycobacterium tuberculosis, humanized transgenic mouse model [more]

Reproductive periodicity, spawning induction, and larval metamorphosis of the hemichordate acorn worm Ptychodera flava

Ching-Yi Lin, Che-Huang Tung, Jr-Kai Yu, Yi-Hsien Su

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution (Wiley) Taiwan, 10 December 2015

Zoology

Key words: Reproductive periodicity, larval metamorphosis, hemichordate [more]

Low Hodgkin/Reed-Sternberg Cell Density Assessed with Automated Image Analysis Is a Poor Prognostic Factor in Classic Hodgkin Lymphoma Patients

Vit Prochazka, Tereza Dyskova, Zuzana Prouzova, Tomas Papajik, Jiri Minarik, Juraj Duras, Jozef Michalka, Alice Sykorova, Peter Mikula, Ludek Raida and Eva Kriegova

Blood (American Society of Hematology) Czech Republic, 03 December 2015

Oncology

Key words: Cell Density, Automated Image Analysis, Prognostic Factor, Hodgkin Lymphoma [more]

Quantitative Analysis of Tissue Inflammation and Responses to Treatment in Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked (IPEX) Syndrome and Review of Literature

Chih-An Chen, Wan-Chen Chung, Yuan-Yow Chiou, Yao-Jong Yang, Yung-Chieh Lin, Hans D Ochs, Dr Chi-Chang Shieh

Journal of Microbiology, Immunology and Infection (Elsevier) Taiwan, USA, 01 December 2015

Immunology, Microbiology

Key words: Immune dysregulation, polyendocrinopathy, enteropathy, X-Linked (IPEX) syndrome, regulatory T cells, T helper 2 cells [more]

Hirsutella sinensis mycelium attenuates bleomycin-induced pulmonary inflammation and fibrosis in vivo

TT Huang, HC Lai, YF Ko, DM Ojcius, YW Lan, J Martel, JD Young,

J Cancer Treat Diagnosis (Nature) Taiwan, USA, 26 November 2015

Microbiology

Key words: Drug development, Inflammasome [more]

Dynamic Trk and G Protein Signalings Regulate Dopaminergic Neurodifferentiation in Human Trophoblast Stem Cells

Eing-Mei Tsai, Yu-Chih Wang, Tony Tung-Yin Lee, Cheng-Fang Tsai, Hung-Sheng Chen, Feng-Jie Lai, Kazunari K Yokoyama, Tsung-Hsun Hsieh, Ruey-Meei Wu, Jau-nan Lee

PLoS One (PLOS) Taiwan, USA, 25 November 2015

Neuroscience

Key words: Neurons, DNA transcription, G-protein signaling, stem cells, genomic signal processing, retinoic acid signaling cascade, retinoid signaling, neuronal differentiation [more]

Curcumin Suppresses Phthalate-Induced Metastasis and the Proportion of Cancer Stem Cell (CSC)-like Cells via the Inhibition of AhR/ERK/SK1 Signaling in Hepatocellular Carcinoma

Cheng-Fang Tsai, Tsung-Hua Hsieh, Jau-Nan Lee, Chia-Yi Hsu, Yu-Chih Wang, Kung-Kai Kuo, Hua-Lin Wu, Chien-Chih Chiu, Eing-Mei Tsa, and Po-Lin Kuo

Journal of Agricultural and Food Chemistry (ACS Publications) Taiwan, 20 November 2015

Oncology

Key words: Phthalate, curcumin, hepatocellular carcinoma, metastasis, side population, cancer stem cells [more]

Alpha-Actinin 4 Is Associated with Cancer Cell Motility and Is a Potential Biomarker in Non–Small Cell Lung Cancer

MC Wang, YH Chang, CC Wu, YC Tyan, HC Chang, YG Goan, WW Lai, PN Cheng, PC Liao

Journal of Thoracic Oncology (Elsevier) Taiwan, 20 November 2015

Oncology

Key words: ACTN4, non–small-cell lung cancers, CL1-0 and CL1-5 cell lines, siRNA [more]

MiR-125b is critical for fibroblast-to-myofibroblast transition and cardiac fibrosis

Varun Nagpal, Rahul Rai, Aaron T Place, Sheila B Murphy, Suresh K Verma, Asish K Ghosh, and Douglas E Vaughan

Circulation (AHA Journals) USA, 19 November 2015

Cardiology

Key words: RNA sequence, fibrosis, angiotensin II, transforming growth factor, miR-125b [more]

IMPS-11 Expression and prognostic impact of immune modulatory molecule PD-L1 in meningioma

Seunggu Han, Gerald Reis, Gary Kohanbash, Shruti Srivastav, Stephen Magill, Annette Molinaro, Michael McDermott, Philip Theodosopoulos, Manish Aghi, Mitchel Berger, Igor Barani, Joanna Phillips, Arie Perry, Hideho Okada

Neuro-Oncology (Oxford University Press) USA, 09 November 2015

Oncology

Key words: meningioma, patient prognosis, impact, molecule, programmed cell death 1 ligand 1 [more]

CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow

A Nakamura-Ishizu, K Takubo, H Kobayashi, K Suzuki-Inoue, T Suda

Journal of Experimental Medicine (Rockefeller University Press) Japan, 09 November 2015

Stem Cell Research

Key words: CLEC-2, megakaryocyte, hematopoietic stem cells, bone marrow [more]

Transdermal drug targeting and functional imaging of tumor blood vessels in the mouse auricle

H Schröder, D Komljenovic, M Hecker, T Korff

The FASEB Journal (FASEB) Germany, 06 November 2015

Oncology

Key words: angiogenesis • blood vessel growth • bortezomib • mouse model • perfusion [more]

Melanin pigmentation in rat eyes: in vivo imaging by polarization-sensitive optical coherence tomography and comparison to histology

Bernhard Baumann, Johannes Schirmer, Sabine Rauscher, Stanislava Fialová, Martin Glösmann, Marco Augustin, Michael Pircher, Marion Gröger, Christoph K Hitzenberger

Investigative Ophthalmology & Visual Science (ARVO Journals) Austria, 01 November 2015

Ophthalmology

Key words: Melanin Pigmentation, Eyes, In Vivo Imaging, Polarization-Sensitive Optical Coherence Tomography [more]

Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-a Production in Women

Morgane Griesbeck, Susanne Ziegler, Sophie Laffont, Nikaïa Smith, Lise Chauveau, Phillip Tomezsko, Armon Sharei, Georgio Kourjian, Filippos Porichis, Meghan Hart, Christine D Palmer, Michael Sirignano, Claudia Beisel, Heike Hildebrandt, Claire Cénac, Alexandra-Chloé Villani, Thomas J Diefenbach, Sylvie Le Gall, Olivier Schwartz, Jean-Philippe Herbeuval, Brigitte Autran, Jean-Charles Guéry, J Judy Chang, and Marcus Altfeld

The Journal of Immunology (American Association of Immunologists) France, Germany, UK, Australia, 30 October 2015

Immunology

Key words: Plasmacytoid dendridic cell levels, IRF5 [more]

Astrocytic CCAAT/Enhancer-Binding Protein Delta Contributes to Glial Scar Formation and Impairs Functional Recovery After Spinal Cord Injury

Shao-Ming Wang, Jung-Yu C Hsu, Chiung-Yuan Ko, Nai-En Chiu, Wai-Ming Kan, Ming-Derg Lai, Ju-Ming Wang

Molecular Neurobiology (Springer) Taiwan, 28 October 2015

Neuroscience

Key words: Astrogliosis C/EBPd, MMP-3 RhoA, astrocyte migration [more]

Novel p53-dependent anticancer strategy by targeting iron signaling and BNIP3L-induced mitophagy

Nastasia Wilfinger, Shane Austin, Barbara Scheiber-Mojdehkar, Walter Berger, Siegfried Reipert, Monika Praschberger, Jakob Paur, Robert Trondl, Bernhard K Keppler, Christoph C Zielinski, and Karin Nowikovsky

Oncotarget (Impact Journals) Austria, 26 October 2015

Oncology

Key words: cancer, p53, BNIP3L, mitophagy, gallium complex [more]

Quantitative Image Analysis of Epithelial and Stromal Area in Histological Sections of Colorectal Cancer: An Emerging Diagnostic Tool.

R Rogojanu, T Thalhammer, U Thiem, A Heindl, I Mesteri, A Seewald, W Jäger, C Smochina, I Ellinger, G Bises

Biomed Research International (Hindawi Publishing Corporation) Austria, Romania, 22 October 2015

Oncology

Key words: Image analysis, histology, colorectal cancer, diagnosis tool [more]

Glucose-regulated protein 94 mediates cancer progression via AKT and eNOS in hepatocellular carcinoma

Chien-Yu Huang, Uyanga Batzorig, Wan-Li Cheng, Ming-Te Huang, Wei- Yu Chen, Po-Li Wei, Yu-Jia Chang

Tumor Biology (Springer) Taiwan, Mongolia, 22 October 2015

Oncology

Key words: GRP94 HCC eNOS AKT Proliferation [more]

Redox Regulation of Pro-IL-1β Processing May Contribute to the Increased Severity of Serum-Induced Arthritis in NOX2-Deficient Mice

Ya-Fang Huang, Pei-Chi Lo, Chia-Liang Yen, Peter Andrija Nigrovic, Wen-Chen Chao, Wei-Zhi Wang, George Chengkang Hsu, Yau-Sheng Tsai, and Chi-Chang Shieh

Antioxidants and Redox Signaling (Mary Ann Liebert Inc.) Taiwan, USA, 21 October 2015

Rheumatology

Key words: Redox Regulation, Pro-IL-1β, Serum-Induced Arthritis, NOX2 [more]

An Emerging Approach for Parallel Quantification of Intracellular Protozoan Parasites and Host Cell Characterization Using TissueFAXS Cytometry

Maximilian Schmid, Bianca Dufner, Julius Dürk, Konstanze Bedal, Kristina Stricker, Lukas Ali Prokoph, Christoph Koch, Anja K Wege, Henner Zirpel, Ger van Zandbergen, Rupert Ecker, Bogdan Boghiu, Uwe Ritter

PLoS One (PLOS) Germany, Austria, 21 October 2015

Parasitology

Key words: Macrophages, parasitic diseases, host cells, leishmania major, DAPI staining, cell staining, host-pathogen interactions, intracellular pathogens [more]

The Role of Lysophosphatidic Acid on Airway Epithelial Cell Denudation in a Murine Heterotopic Tracheal Transplant Model

Yukiko Tando, Chiharu Ota, Mitsuhiro Yamada, Satoshi Kamata, Mutsuo Yamaya, Kuniyuki Kano, Shinichi Okudaira, Junken Aoki, and Hiroshi Kubo,

Transplantation (Wolters Kluwer) Japan, 19 October 2015

Transplantation Medicine

Key words: Lysophosphatidic Acid, Airway Epithelial Cells, Denudation, Murine Heterotopic Tracheal Transplant Model [more]

Development of recombinant collagen-peptide-based vehicles for delivery of adipose-derived stromal cells (ADSC)

M Parvizi, JA Plantinga, C van Spreuwel-Goossens, S van Dongen, S G Kluijtmans, MC Harmsen

Journal of Biomedical Materials Research (Wiley) The Netherlands, 14 October 2015

Biomaterials

Key words: Recombinant-Collagen Microspheres, integrin binding motives, crosslinked, ADSC, delivery [more]

Cardioprotective Actions of TGFßRI Inhibition Through Stimulating Autocrine/Paracrine of Survivin and Inhibiting Wnt in Cardiac Progenitors

Yu-Sian Ho, Wan-Hsuan Tsai, Fen-Chiung Lin, Wei-Pang Huang, Lung-Chun Lin, Sean M Wu, Yu-Ru Liu, Wen-Pin Chen

Stem Cells (Wiley) Taiwan, USA, 10 October 2015

Stem Cell Research

Key words: Nkx2.5, sca1, Birc5, survivin, MEK/ERK, Wnt3a [more]

YAP1 Is a Driver of Myofibroblast Differentiation in Normal and Diseased Fibroblasts

Bram Piersma, Saskia de Rond, Paul MN Werker, Stellar Boo, Boris Hinz, Marike M van Beuge, Ruud A Bank

The American Journal of Pathology (Elsevier) The Netherlands, Canada, 10 October 2015

Pathology

Key words: Myofibroblast, fibroblasts, YAP 1 [more]

The pro-fibrotic properties of transforming growth factor on human fibroblasts are counteracted by caffeic acid by inhibiting myofibroblast formation and collagen synthesis

Masum M Mia, Ruud A Bank

Cell and Tissue Research (Springer) The Netherlands, 09 October 2015

Cell Biology

Key words: Fibrosis, collagen, myofibroblasts, caffeic acid, lysyl hydroxylase [more]

Characterization of sulfur mustard resistant keratinocyte cell line HaCaT/SM

Wolf Markus, Siegert Markus, Rothmiller Simone, Scheithauer Nina, Strobelt Romano, Steinritz Dirk, Thiermann Horst, Schmidt Annette

Toxicology Letters (Elsevier) Germany, 09 October 2015

Toxicology

Key words: Sulfur mustard, resistance, keratinocytes [more]

YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model

Tsion Zewdu Minas, Jenny Han, Tahereh Javaheri, Sung-Hyeok Hong, Michaela Schlederer, Yasemin Saygideğer-Kont, Haydar Çelik, Kristina M Mueller, Idil Temel, Metin Özdemirli, Heinrich Kovar, Hayriye Verda Erkizan, Jeffrey Toretsky, Lukas Kenner, Richard Moriggl,and Aykut Üren

Oncotarget (Impact Journals) USA, Austria, 08 October 2015

Oncology

Key words: EWS-FLI1, ETS fusion proteins, YK-4-279, ewing sarcoma, erythoid leukemia [more]

Synergy of endothelial and neural progenitor cells from adipose-derived stem cells to preserve neurovascular structures in rat hypoxic-ischemic brain injury

Yuan-Yu Hsueh, Ya-Ju Chang, Chia-Wei Huang, Fitri Handayani, Yi-Lun Chiang, Shih-Chen Fan, Chien-Jung Ho, Yu-Min Kuo, Shang-Hsun Yang, Yuh-Ling Chen, Sheng-Che Lin, Chao-Ching Huang and Chia-Ching Wu

Scientific Reports (Nature) Taiwan, 08 October 2015

Neuroscience

Key words: Neural progenitors, stem cells, brain injury [more]

Sympathetic Neurotransmitters Modulate Osteoclastogenesis and Osteoclast Activity in the Context of Collagen-Induced Arthritis

Dominique Muschter, Nicole Schäfer, Hubert Stangl, Rainer H Straub, Susanne Grässel

PLoS One (PLOS) Germany, 02 October 2015

Rheumatology

Key words: Osteoclasts, neurotransmitters, arthritis, macrophages, apoptosis, gene expression, adenylyl cyclase, immune receptors [more]

Intestinal Epithelial Cell Tyrosine Kinase 2 Transduces IL-22 Signals To Protect from Acute Colitis

Eva Hainzl, Silvia Stockinger, Isabella Rauch, Susanne Heider, David Berry, Caroline Lassni, Clarissa Schwab, Felix Rosebrock, Gabriel Milinovich, Michaela Schlederer, Michael Wagner, Christa Schleper, Alexander Loy, Tim Urich, Lukas Kenner, Xiaonan Han, Thomas Decker, Birgit Strobl, Mathias Müller

The Journal of Immunology (American Association of Immunologists) Austria, USA, 02 October 2015

Gastroenterology

Key words: Intestinal epithelial cell, acute colitis [more]

The decrease in histone methyltransferase EZH2 in response to fluid shear stress alters endothelial gene expression and promotes quiescence

Monika Maleszewska, Byambasuren Vanchin, Martin C Harmsen, Guido Krenning

Angiogenesis (Springer) The Netherlands, Germany, 28 September 2015

Cell Biology

Key words: Endothelial cell, enhancer of zeste homolog-2 (EZH2), fluid shear stress (FSS), mechanotransduction, chromatin [more]

Putative Prostate Cancer Risk SNP in an AR Binding Site of the Melanophilin Gene Illustrates Enrichment of Risk SNPs in AR Target Sites

Huajie Bu, Narisu Narisu, Bettina Schlick, Johannes Rainer, Thomas Manke, Georg Schäfer, Lorenza Pasqualini, Peter Chines, Michal R Schweiger, Christian Fuchsberger, Helmut Klocker

Human Mutation (Wiley) Austria, Germany, Italy, USA, 28 September 2015

Oncology

Key words: Prostate cancer, risk SNPs, androgen receptor, melanophilin, MLPH, androgen regulation, AR [more]

A sunblock based on bioadhesive nanoparticles

Y Deng, A Ediriwickrema, F Yang, J Lewis, M Girardi, WM Saltzman

Nature Materials (Nature) USA, 28 September 2015

Nanomedicine

Key words: Biomedical engineering, Drug delivery [more]

Amelioration of Chemotherapy-Induced Intestinal Mucositis by Orally Administered Probiotics in a Mouse Model

Chun-Yan Yeung, Wai-Tao Chan, Chun-Bin Jiang, Mei-Lien Cheng, Chia-Yuan Liu, Szu-Wen Chang, Jen-Shiu Chiang Chiau, Hung-Chang Lee

PLoS One (PLOS) Taiwan, 25 September 2015

Oncology

Key words: Probiotics, gastrointestinal tract, diarrhea, mouse models, cytokines, jejunum, lactobacillus, cancer treatment [more]

The great escape: Pseudomonas breaks out of the lung

A Zhang, SM Rangel, AR Hauser

Microbial Cell (NCBI) USA, 23 September 2015

Microbiology

Key words: Pseudomonas aeruginosa, ExoS, pneumonia, dissemination [more]

Type 3 innate lymphoid cells maintain intestinal epithelial stem cells after tissue damage

Patricia Aparicio-Domingo, Monica Romera-Hernandez, Julien J Karrich, Ferry Cornelissen, Natalie Papazian, Dicky J Lindenbergh-Kortleve, James A Butler, Louis Boon, Mark C Coles, Janneke N Samsom, Tom Cupedo

Journal of Experimental Medicine (Rockefeller University Press) The Netherlands, UK, 21 September 2015

Stem Cell Research

Key words: Type 3 innate lymphoid cells, intestinal epithelial stem cells, tissue damage [more]

Bone marrow micro-environmental CD4+ and CD8+ lymphocyte infiltration patterns define overall- and progression free survival in standard risk Multiple Myeloma – an analysis from the Austrian Myeloma Registry

Wolfgang Willenbacher, Ella Willenbacher, Claudia Zelle-Rieser, Rainer Biedermann, Roman Weger, Karin Jöhrer, Andrea Brunner

Leukemia and Lymphoma (Taylor and Francis) Austria, 19 September 2015

Oncology

Key words: Bone marrow, lymphocite infiltration, myeloma [more]

Quantitative functional MRI in a clinical orthotopic model of pancreatic cancer in immunocompetent Lewis rats

Zhuoli Zhang, Linfeng Zheng, Weiguo Li, Andrew C Gordon, Yi Huan, Junjie Shangguan, Daniel Procissi, David J Bentrem, Andrew C Larson

American Journal of Translational Research (e-Century Publishing Corporation) USA, China, 15 September 2015

Oncology

Key words: Magnetic resonance imaging, imaging biomarker, pancreatic cancer, immunocompetent Lewis rats [more]

Nuclear HDAC6 inhibits invasion by suppressing NF-κB/MMP2 and is inversely correlated with metastasis of non-small cell lung cancer

CJ Yang, YP Liu, HY Dai, YL Shiue, CJ Tsai, MS Huang, YT Yeh

Oncotarget (Impact Journals) Taiwan, 15 September 2015

Oncology

Key words: HDAC6, NF-κB, MMP2, metastasis, lung cancer [more]

Sulfur and nitrogen mustards induce characteristic poly(ADP-ribosyl)ation responses in HaCaT keratinocytes with distinctive cellular consequences

Aswin Mangerich, Malgorzata Debiak, Matthias Birtel, Viviane Ponath, Frank Balszuweit, Kirsten Lex, Rita Martello, Waltraud Burckhardt-Boer, Romano Strobelt, Markus Siegert, Horst Thiermanb, Dirk Steinritz, Annette Schmidt, Alexander Bürkle

Toxicology Letters (Elsevier) Germany, 14 September 2015

Toxicology

Key words: Poly(ADP-ribose), PARP inhibitors, sulfur mustard, nitrogen mustard, genotoxicity, HaCaT, mass spectrometry, micronucleus [more]

Efficient therapy of ischaemic lesions with VEGF121-fibrin in an animal model of systemic sclerosis.

Allipour Birgani S, Mailänder M, Wasle I, Dietrich H, Gruber J, Distler O, Sgonc R

Annals of the Rheumatic Diseases (BMJ Journals) Austria, Switzerland, 11 September 2015

Rheumatology

Key words: Outcomes research, systemic sclerosis, treatment [more]

The ß-catenin signaling pathway induces aggressive potential in breast cancer by up-regulating the chemokine CCL5

Rika Yasuhara, Tarou Irié, Kenya Suzuki, Terumasa Sawada, Noriko Miwa, Akiko Sasaki, Yuko Tsunoda, Seigo Nakamura, Kenji Mishima

Experimental Cell Research (Elsevier) Japan, 10 September 2015

Oncology

Key words: ß-Catenin, metastasis, breast cancer, cytokines, CCL5 [more]

Sur8/Shoc2 promotes cell motility and metastasis through activation of Ras-PI3K signaling

S Kaduwal, WJ Jeong, JC Park, KH Lee, YM Lee, SH Jeon, YB Lim, DS Min, KY Choi

Oncotarget (Impact Journals) South Korea, 05 September 2015

Oncology

Key words: Sur8, Ras, PI3K, cell migration, metastasis [more]

The IκB kinase inhibitor ACHP strongly attenuates TGF β1‐induced myofibroblast formation and collagen synthesis

Masum M Mia, Ruud A Bank

Journal of Cellular and Molecular Medicine (Wiley) The Netherlands, 04 September 2015

Cell Biology

Key words: Fibrosis, collagen, myofibroblasts, fibronectin, lysyl hydroxylase [more]

Molecular profiling of long-term survivors identifies a subgroup of glioblastoma characterized by chromosome 19/20 co-gain

Christoph Geisenberger, Andreas Mock, Rolf Warta,Carmen Rapp, Christian Schwager, Andrey Korshunov, Ann-Katrin Nied, David Capper, Benedikt Brors, Christine Jungk, David Jones, V Peter Collins, Koichi Ichimura, L Magnus Bäcklund, Elena Schnabel, Michel Mittelbron, Bernd Lahrmann, Siyuan Zheng, Roel G W Verhaak, Niels Grabe, Stefan M Pfister, Christian Hartmann, Andreas von Deimling, Jürgen Debus, Andreas Unterberg, Amir Abdollahi, Christel Herold-Mende

Acta Neuropathologica (Springer) Germany, UK, Japan, Sweden, USA, 01 September 2015

Pathology

Key words: Glioblastoma, molecular profiling, microglia, long-term survival, short-term survival [more]

Increased complexity in carcinomas: analyzing and modeling the interaction of human cancer cells with their microenvironment

Mira Stadler, Stefanie Walter, Angelika Walzl, Nina Kramer, Christine Unger, Martin Scherze, Daniela Unterleuthner, Markus Hengstschläger, Georg Krupitza, Helmut Dolznig

Seminars in Cancer Biology (Elsevier) Austria, 28 August 2015

Oncology

Key words: Carcinoma, human cancer cells, microenvironment

SPIO-labeled yttrium microspheres for MR imaging quantification of transcatheter intrahepatic delivery in a rodent model

W Li, Z Zhang, AC Gordon, J Chen, J Nicolai, RJ Lewandowski, RA Omary, AC Larson

Radiology (Radiological Society of North America) USA, 27 August 2015

Bioimaging

[more]

Vascular Proteomics Reveal Novel Proteins Involved in SMC Phenotypic Change: OLR1 as a SMC Receptor Regulating Proliferation and Inflammatory Response

Dong Hoon Kang, Mina Choi, Soyoung Chang, Min Young Lee, Doo Jae Lee, Kyungsun Choi, Junseong Park, Eun Chun Han, Daehee Hwang, Kihwan Kwon, Hanjoong Jo, Chulhee Choi, Sang Won Kang

PLoS One (PLOS) South Korea, 25 August 2015

Cell Biology

Key words: Carotid arteries, small interfering RNAs, transfection, proteomics, membrane proteins, immunohistochemistry techniques, protein interaction networks, network analysis [more]

Acceleration of atherogenesis in ApoE−/− mice exposed to acute or low-dose-rate ionizing radiation

Mariateresa Mancuso, Emanuela Pasquali, Ignacia Braga-Tanaka, Satoshi Tanaka, Alessandro Pannicelli, Paola Giardullo, Simonetta Pazzaglia, Soile Tapio, Michael J Atkinson, Anna Saran

Oncotarget (Impact Journals) Italy, Japan, Germany, 22 August 2015

Oncology

Key words: Atherosclerosis, ApoE mice, radiation, aorta [more]

Stefin B deficiency reduces tumor growth via sensitization of tumor cells to oxidative stress in a breast cancer model

M Butinar, M T Prebanda, J Rajkovic, B Jeric, V Stoka, C Peters, T Reinheckel, A Krüger, V Turk, B Turk and O Vasiljeva

Oncogene (Nature) Slovenia, Germany, USA, 19 August 2015

Oncology

Key words: Tumor cells, oxidative stress, breast cancer [more]

Differential Utilization of Dietary Fatty Acids in Benign and Malignant Cells of the Prostate

Andrea Dueregger, Bernd Schöpf, Theresa Eder, Julia Höfer, Erich Gnaiger, Astrid Aufinger, Lukas Kenner, Bernhard Perktold, Reinhold Ramoner, Helmut Klocker, Iris E Eder

PLoS One (PLOS) Austria, 18 August 2015

Oncology

Key words: Prostate gland, mitochondria, glucose, glucose metabolism, mitochondrial DNA, fatty acids, cell metabolism, prostate cancer [more]

Impact of CYP24A1 overexpression on growth of colorectal tumour xenografts in mice fed with vitamin D and soy

Julia Höbaus, Samawansha Tennakoon, Petra Heffeter, Charlotte Groesche, Abhishek Aggarwal, Doris M Hummel, Ursula Thiem, Rodrig Marculescu, Walter Berger, Enikö Kállay

International Journal of Cancer (Wiley) Austria, 17 August 2015

Oncology

Key words: Colon cancer, vitamin D, CYP24A1, soy, xenograft [more]

Interleukin 2 Topical Cream for Treatment of Diabetic Foot Ulcer: Experiment Protocol

SWS Chan

JMIR Research Protocols (JMIR Publications) USA, 14 August 2015

Dermatology

Key words: type 1 diabetes, topical cream, chronic wound healing, immunotherapy, IL-2 [more]

An Echinococcus multilocularis antigen B3 proteoform that shows specific antibody responses against active stage alveolar echinococcosis

CS Ahn, H Cai, JG Kim, X Han, X Ma, YA Bae, HJ Yang, I Kang, H Wang, Y Kong

Journal of Clinical Microbiology (American Society for Microbiology) China, South Korea, 12 August 2015

Microbiology

Key words: Echinococcus multilocularis, Antigen B3, Antibody Response, Alveolar Echinococcosis [more]

Mesenchymal stem cell-based HSP70 promoter-driven VEGFA induction by resveratrol alleviates elastase-induced emphysema in a mouse model

Young-Bin Chen, Ying-Wei Lan, Lih-Geeng Chen, Tsung-Teng Huang, Kong-Bung Choo, Winston T K Cheng, Hsuan-Shu Lee, Kowit-Yu Chong

Cell Stress and Chaperones (Springer) China, 05 August 2015

Cell Biology

Key words: Stem cell-based gene therapy, resveratrol Hsp70 promoter VEGFA, mouse model, emphysema [more]

Abstract 1091: A new image processing approach for functional context-based analysis of tryptase positive mast cells in cutaneous T-cell lymphomas

Radu Rogojanu, Johanna Eder, Waltraud Jerey, Gabriele Klosner, Verene Paulitschke, Isabella Ellinger, Theresia Thalhammer, Dan Kolmer, Franz Trautinger

Cancer Research (AACR Publications) Austria, 01 August 2015

Oncology

Key words: Image processing, tryptase positive mast cells, cutaneous, T-cell lymphoma [more]

Abstract 1292: Validation study on quantitative analysis method of interrelationships between immune cells and prostate epithelial and cancer cells

Gero Kramer, Lukas Kenner, Thomas Szekeres, Shahrokh Shariat, Sarah Schwarz

Cancer Research (AACR Publications) Austria, 01 August 2015

Oncology

Key words: Quantitative analysis, immune cells, prostate epithelial, cancer cells [more]

Early inflammatory responses following cell grafting in the CNS trigger activation of the subventricular zone: a proposed model of sequential cellular events

Praet J, Santermans E, Daans J, Le Blon D, Hoornaert C, Goossens H, Hens N, Van der Linden A, Berneman Z, Ponsaerts P

Cell Transplantation (SAGE Journals) Belgium, 01 August 2015

Neuroscience

Key words: Cell transplantation, Graft apoptosis, Immune response, Angiogenesis, Cell proliferation [more]

Exchange Protein Directly Activated by cAMP (EPAC) Regulates Neuronal Polarization through Rap1B

Pablo Muñoz-Llancao, Daniel R Henríquez, Carlos Wilson, Felipe Bodaleo, Erik W Boddeke, Frank Lezoualc'h, Martina Schmidt, Christian González-Billault

Journal of Neuroscience (Society for Neuroscience) The Netherlands, Chile, France, 01 August 2015

Neuroscience

Key words: Exchange protein, cAMP, neuronal polarization, Rap1B [more]

Significant Therapeutic Efficacy with Combined Radioimmunotherapy and Cetuximab in Preclinical Models of Colorectal Cancer

Vessela Vassileva, Vineeth Rajkumar, Mario Mazzantini, Mathew Robson, Adam Badar, Surinder Sharma, Erik Årstad, Daniel Hochhauser, Mark F Lythgoe, Geoffrey M Boxer, Rosmund Barbara Pedley

The Journal of Nuclear Medicine (SNMMI) UK, 01 August 2015

Oncology

Key words: Radioimmunotherapy, cetuximab, colorectal cancer [more]

Outcome in Heart Failure with Preserved Ejection Fraction: The Role of Myocardial Structure and Right Ventricular Performance

Georg Goliasch, Caroline Zotter-Tufaro, Stefan Aschauer, Franz Duca, Benedikt Koell, Andreas A Kammerlander, Robin Ristl, Irene M Lang, Gerald Maurer, Julia Mascherbauer, Diana Bonderman

PLoS One (PLOS) Austria, 30 July 2015

Cardiology

Key words: Extracellular matrix, biopsy, blood pressure, heart failure, hemodynamics, echocardiography, pulmonary arteries, ejection fraction [more]

Elevated S100A9 expression in tumor stroma functions as an early recurrence marker for early-stage oral cancer patients through increased tumor cell invasion, angiogenesis, macrophage recruitment and interleukin-6 production

WY Fang, YW Chen, JR Hsiao, CS Liu, YZ Kuo, YC Wang, KC Chang, ST Tsai, MZ Chang, SH Lin, LW Wu

Oncotarget (Impact Journals) Taiwan, 22 July 2015

Oncology

Key words: S100A9, oral cancer, recurrence, IL-6, macrophages [more]

Development of Blood and Lymphatic Endothelial Cells in Embryonic and Fetal Human Skin

Schuster C, Mildner M, Botta A, Nemec L, Rogojanu R, Beer L, Fiala C, Eppel W, Bauer W, Petzelbauer P, Elbe-Bürger A

The American Journal of Pathology (Elsevier) Austria, 16 July 2015

Pathology

Key words: Blood, lymphatic endothelial cells, embryonic, fetal human skin [more]

POLE Proofreading Mutations Elicit an Antitumor Immune Response in Endometrial Cancer

Inge C van Gool, Florine A Eggink, Luke Freeman-Mills, Ellen Stelloo, Emanuele Marchi, Marco de Bruyn, Claire Palles, Remi A Nout, Cor D de Kroon, Elisabeth M Osse, Paul Klenerman, Carien L Creutzberg, Ian PM Tomlinson, Vincent THBM Smit, Hans W Nijman, Tjalling Bosse, David N Church

Clinical Cancer Research (AACR Publications) The Netherlands, UK, 15 July 2015

Oncology

Key words: Pole proofreading mutation, antitumor, immune response, endometrial cancer [more]

Langerhans Cells Maintain Local Tissue Tolerance in a Model of Systemic Autoimmune Disease

Jennifer K King, Rachael L Philips, Anna U Eriksson, Peter J Kim, Ramesh C Halder, Delphine J Lee, Ram Raj Singh

The Journal of Immunology (American Association of Immunologists) USA, 15 July 2015

Immunology

Key words: Lupus, langerhans cells [more]

mi R‐135b‐and mi R‐146b‐dependent silencing of calcium‐sensing receptor expression in colorectal tumors

Irfete S Fetahu, Samawansha Tennakoon, Kate E Lines, Charlotte Gröschel, Abhishek Aggarwal, Ildiko Mesteri, Sabina Baumgartner‐Parzer, Robert M Mader, Rajesh V Thakker, Enikő Kállay

International Journal of Cancer (Wiley) Austria, UK, 14 July 2015

Oncology

Key words: calcium‐sensing receptor, microRNAs, colorectal cancer, miR‐135b, miR‐146b [more]

miR-135b- and miR-146b-dependent silencing of calcium-sensing receptor expression in colorectal tumors

Irfete S Fetahu, Samawansha Tennakoon, Kate E Lines, Charlotte Gröschel, Abhishek Aggarwal, Ildiko Mesteri, Sabina Baumgartner-Parzer, Robert M Mader, Rajesh V Thakker, Eniko Kállay

International Journal of Cancer (Wiley) Austria, UK, 14 July 2015

Oncology

Key words: Calcium-sensing receptor, microRNAs, colorectal cancer, miR-135b, miR-146b [more]

Tumor dosimetry for I-131 trastuzumab therapy in a Her2+ NCI N87 xenograft mouse model using the Siemens SYMBIA E gamma camera with a pinhole collimator

Young Sub Lee, Jin Su Kim, Kyung Deuk Cho, Joo Hyun Kang, Sang Moo Lim

Journal of Instrumentation (IOP Science) South Korea, 06 July 2015

Oncology

Key words: Tumor dosimetry, xenograft mouse model, gamma camera, Siemens [more]

Male-Specific Alleviation of Iron-Induced Striatal Injury by Inhibition of Autophagy

Li-Fang Wang, Kazunari K Yokoyama, Tzu-Yin Chen, Hsiu-Wen Hsiao, Pei-Chi Chiang, Ya-Ching Hsieh, Steven Lo, Chin Hsu

PLoS One (PLOS) Taiwan, USA, 06 July 2015

Neuroscience

Key words: Autophagic cell death, neurons, neostriatum, neuronal tuning, histology, DNA fragmentation, mice, ovariectomy [more]