Dr. Namrata Bhattacharya, Peter MacCallum Cancer Centre, presents her work on SCellBOW (Single-Cell Bag-of-Words) - a novel computational approach that facilitates effective identification and high-quality visualization of single-cell subpopulations.

Wang et al. used spatial transcriptomics to characterize subsets of tumor-associated macrophages (TAMs) known as monocyte-derived TAMs. They identified a cluster of hypoxia-TAM oversecreting adrenomedullin, confirmed by multiplex immunostaining with TissueFAXS Spectra imaging platform, and StrataQuest image analysis software was employed for marker identification.