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Application Note

14 Oct, 2024

Quantitative Analysis of Cultured Cells: High-End Solution for Ready-To-Publish Data

A case study using StrataQuest image analysis on IF-processed cultured cells. The workflow automated cell identification, nuclei and cytoplasm counting, and marker intensity quantification.

intracellular analysis

image analysis

cell quantification

cell culture

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Customer Publication

20 May, 2022

The Effect of Neutrophil Extracellular Traps (NETs) on Fertility

Zambrano et al. (MDPI Animals) visualized neutrophil extracellular traps (NETs) in bull sperm–neutrophil co-cultures using TissueFAXS i PLUS, revealing cytotoxic effects of NET-derived proteins/enzymes on sperm viability and fertility potential.

intracellular analysis

cell-to-cell interaction

disease modeling

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Customer Publication

06 Dec, 2021

Tissue Cytometry in Anti-SARS-CoV-2 Drug Discovery

Zhang et al. (Signal Transduction Targeted Therapy) studied Azvudine in SARS-CoV-2 infected macaques and COVID-19 patients. TissueFAXS Q and TissueQuest quantified viral load, immune status, and TUNEL staining in thymus tissue.

intracellular analysis

cell quantification

infectious diseases

drug discovery

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Webinar

03 May, 2021

Automated Imaging of Metabolic Enzyme Activity in the Skin

Prof. Florian Gruber and Christopher Kremslehner (MedUni Vienna) present a metabolic imaging workflow integrating TissueFAXS i PLUS and StrataQuest to study UV-induced effects on skin (Redox Biology).

intracellular analysis

spatial analysis

cell phenotyping

regenerative medicine

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Customer Publication

31 Mar, 2021

In Situ Immunophenotyping in Foreign Body Reaction

A study in Hernia (Prof. Uwe Klinge, Univ. Aachen) used TG’s tissue cytometry to characterize adaptive and innate immune cells in foreign body reaction, including high-content immunophenotyping and proximity analysis.

intracellular analysis

immunophenotyping

immunology

disease modeling

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Customer Publication

12 Nov, 2020

Exploration of neuronal diversity among various species (HCN expression)

A recent publication in the Journal of Neuroscience Research from a research group from Medical University of Innsbruck addresses expression patterns, subcellular location, and age-dependent changes of HCN (voltage gated channel) across different mammalian species. TissueFAXS PLUS and HistoQuest were used to assess expression of HCN in-situ.

intracellular analysis

neuroscience

cell phenotyping

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TissueGnostics provides advanced solutions for whole-slide imaging and image analysis in biological and clinical research. Our products help researchers to scan and analyze complex tissue samples, enabling more detailed insights into tissue structure, cellular interactions, and spatial cell landscape.

 

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