Featured Articles

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Webinar

26 May, 2025

Exploring Immune Cell Interactions and Tissue Regeneration through Imaging

immunophenotyping

organoid detection

immunology

regenerative medicine

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Application Note

12 Mar, 2025

Investigating T-Cell Communities in Immune Tissues with StrataQuest 8

image analysis

spatial analysis

multiplex IF

immunology

Latest Articles

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White Paper

03 Sep, 2025

Advanced Imaging Reveals Why Some Breast Cancers Resist Treatment

Breast cancer continues to affect millions of people around the world—and for most, the diagnosis involves a hormone receptor-positive subtype.

oncology

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Event

29 Aug, 2025

Meet Us at the Annual Meeting of the Australian and New Zealand Society for Immunology (ASI)

TissueGnostics will be at the ASI 2025 meeting, 1–5 December in Perth, Australia. Join one of the region’s largest immunology events and meet our team to discuss your imaging needs.

tissue slide scanners

image analysis

immunology

collaboration

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Event

20 Aug, 2025

Highlights from TissueGnostics’ IUIS 2025 Industry Session

TissueGnostics’ industry session at IUIS 2025 was a success, uniting immunologists around advances in spatial biology and AI-powered imaging. Thanks to Dr. Ecker, A/Prof. Mechtcheriakova, Prof. Batra, and all who joined us. Until next time!

spatial analysis

immunology

omics research

AI-powered analysis

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App

30 Jul, 2025

New StrataQuest App: IF ARTIFICIAL SKIN

The IF Artificial Skin App stratifies skin equivalents into dermis and epidermis, further dividing the epidermis into stratum corneum, suprabasal, and basal layers. It outputs area, mean staining intensity, nuclei counts, and % of marker-positive cells for each layer and sublayer. Read publication here 

tissue segmentation

cell phenotyping

disease modeling

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Event

07 Jul, 2025

Uniting against Cancer Relapse: Successful Mid-Term Meeting of the eRaDicate Project

TissueGnostics proudly participated in the recent mid-term meeting and first doctoral school of the Horizon Europe Marie Skłodowska-Curie Doctoral Network (DN) project eRaDicate.

oncology

translational research

collaboration

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News

05 Jun, 2025

MyScope: Free Online Microscopy Training

Microscopy Australia’s MyScope platform offers free online modules with theory, simulators, and quizzes to support training in microscopy techniques.

brightfield

fluorescence

technology advancements

expert insights

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News

11 Jun, 2025

TissueGnostics is an Industrial Partner of SMART Cooperative Research Centre

TG joins SMART CRC as an industrial partner. This $238M initiative accelerates curative therapies for cancer, heart disease, Alzheimer’s, arthritis, and age-related conditions.

oncology

regenerative medicine

technology advancements

collaboration

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Blog Post

26 May, 2025

Investigating CIDs with a Brightfield Microscopy System

Chronic inflammatory diseases (CIDs) involve prolonged inflammation causing tissue damage and dysfunction.

brightfield

immunology

infectious diseases

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Customer Publication

13 May, 2025

Identification of hypoxic macrophages in glioblastoma with therapeutic potential

Wang et al. used spatial transcriptomics to characterize subsets of tumor-associated macrophages (TAMs) known as monocyte-derived TAMs. They identified a cluster of hypoxia-TAM oversecreting adrenomedullin with multiplex immunostaining imaged with TissueFAXS Spectra, and StrataQuest for marker identification.

spatial analysis

tumor microenvironment

immunophenotyping

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Blog Post

12 May, 2025

What is a Tissue Slide Scanner?

Tissue slide scanners combine whole-slide imaging, multispectral analysis, and AI-driven software to deliver quantitative, context-rich insights into cells, tissues, and microenvironments, advancing biomedical research.

tissue slide scanners

digital pathology

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White Paper

01 May, 2025

Epigenetic Carcinogenesis: Quantitative Insights from HistoQuest Analysis

The evolving understanding of cancer biology underscores the pivotal role of epigenetic modifications - heritable yet reversible changes in gene expression that do not alter the DNA sequence.

single-cell analysis

tumor microenvironment

oncology

biomarker discovery

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Webinar

30 Apr, 2025

Unlocking the Lymphoid Structures with Germinal Centers

Dr. Diana Mechtcheriakova, Medical University of Vienna, presents research on lymphoid structures in systemic immunity and anti-cancer responses, with applications in colorectal cancer.

tissue slide scanners

oncology

immunophenotyping

immunology

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White Paper

23 Apr, 2025

The Role of PD-1+ Treg/PD-1+ CTL Ratio and Tertiary Lymphoid Structures in Gastric Cancer

A new study shows PD-1+ Treg/CTL ratio combined with TLS predicts prognosis and treatment response in gastric cancer using mIF, TissueFAXS, and StrataQuest.

oncology

multiplex IF

immunophenotyping

immunology

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Customer Publication

15 Apr, 2025

CD39+CD8+ T Cells as a Marker for Diagnosis and Prognosis of ESCC

A research group in China analyzed CD39+CD8+ T cells in esophageal squamous cell carcinoma. Based on mIF-stained samples acquired on the TissueFAXS platform, they propose these cells as new markers for diagnosis and prognosis.

oncology

biomarker discovery

immunophenotyping

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Customer Publication

09 Apr, 2025

TCL1A+ B Cells Are Critical for TLS Formation and the Prognosis of OSCC

Researchers demonstrate TCL1A+ B cells drive TLS formation in OSCC and serve as a positive prognostic factor using mIF and TissueFAXS imaging.

oncology

biomarker discovery

multiplex IF

immunology

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News

26 Feb, 2025

Call for Papers: Cancer Organoid Co-Culture Models for Enhanced Cancer Research and Modelling

Frontiers in Medicine launches a call for papers on cancer organoid co-culture models, with Prof. Uwe Ritter, Dr. Talita Glaser and Dr. Rupert Ecker (CEO, TissueGnostics) as topic editors. Deadline: 03.09.2025.

oncology

organoid detection

precision medicine

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Webinar

04 Feb, 2025

Using Tissue Cytometry for Investigation of Fatty Liver Disease

This webinar explores how tissue cytometry enables investigation of fatty liver disease, providing insights into liver pathology and immune interactions.

tissue slide scanners

biomarker discovery

immunology

disease modeling

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Blog Post

20 Jan, 2025

What is AI-Powered Tissue Classification?

AI-powered tissue classification applies machine learning to identify and categorize tissue types. It supports consistent, quantitative analysis of morphology, tumor microenvironments, and disease processes in research and diagnostics.

tissue segmentation

AI-powered analysis

digital pathology

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About Us

TissueGnostics provides advanced solutions for whole-slide imaging and image analysis in biological and clinical research. Our products help researchers to scan and analyze complex tissue samples, enabling more detailed insights into tissue structure, cellular interactions, and spatial cell landscape.

 

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