Tissue slide scanners combine whole-slide imaging, multispectral analysis, and AI-driven software to deliver quantitative, context-rich insights into cells, tissues, and microenvironments, advancing biomedical research.

AI-powered tissue classification applies machine learning to identify and categorize tissue types. It supports consistent, quantitative analysis of morphology, tumor microenvironments, and disease processes in research and diagnostics.

Pyknotic nuclei, key indicators of cell death, are critical in histopathology and disease research. Using advanced imaging and TissueGnostics’ IF Pyknotic Nuclei App, researchers can achieve automated, accurate detection and quantification for deeper diagnostic insights.

AI is transforming imaging cytometry by enabling automated, accurate nuclei segmentation and tissue detection. With solutions like StrataQuest, researchers gain higher precision, efficiency, and insights into cellular structures for biomedical research and diagnostics

Dr. Lukas Kenner, Medical University of Vienna, discusses the impact of micro- and nanoplastic particles on human health, in particular potential effect on cancer development.

Precision medicine is reshaping healthcare by tailoring treatment to each patient’s molecular profile. With tools like tissue cytometry, TissueFAXS, and StrataQuest, researchers can uncover genetic drivers, track therapy response, and advance personalized care.

A new study shows that combining type I interferon (MxA) expression with CD8+ T cell density can predict patient response to neoadjuvant treatment in rectal adenocarcinoma. TissueFAXS CHROMA and StrataQuest enabled precise multispectral imaging and analysis.

Image-based cytometry is transforming tissue analysis by combining microscopy with flow cytometry features. It enables rapid, automated characterization of cells in their native environment, advancing pathology, oncology, and precision medicine with AI integration.

Multiplexing enables simultaneous detection of multiple markers in a single tissue sample. By combining advanced staining, automated imaging, and AI-powered analysis, it provides deeper insights into the tumor microenvironment and precision medicine.

A new MDPI Genes special issue, co-authored by Dr. Rupert Ecker (TissueGnostics) & Prof. Jyotsna Batra (QUT), explores genetic mechanisms and digital histopathology in hormone-sensitive cancers. The book covers methods and new insights in cancer biology and is available for free to read.

The IF Dots App in StrataQuest streamlines automated analysis of FISH stainings by detecting nuclei and quantifying dots per cell. This case study shows how the workflow enables accurate, exportable data for genetics research and clinical applications.

FISH enables precise detection of genetic aberrations in cells and is widely applied in diagnostics and personalized medicine. TissueGnostics’ StrataQuest IF Dots App streamlines FISH analysis by automating dot detection and quantification for high-quality data.

FISH is a powerful imaging-based technique for detecting DNA and RNA sequences directly in cells and tissues. This post explores the advantages of FISH, its complementary methods like CISH and RNAscope, and how TG solutions streamline automated FISH analysis.

How does FISH image analysis advance digital pathology? Learn how whole-slide imaging and AI-powered algorithms enable fast, accurate detection of chromosomal abnormalities, streamline workflows, and open new possibilities for precision medicine.

The Institute of Pathophysiology and Allergy Research (MedUni Vienna) has been named a Center of Excellence for Quantitative Digital Microscopy by TissueGnostics, recognizing its pioneering use of the TissueFAXS platform in over 45 high-impact publications.

TG and the University Clinic of Dentistry (Danube Private University) have received FFG funding for AutOPathStage. This project aims to develop a deep learning–based decision support system for classification of oral dysplasia – a disease of the oral cavity with malignant potential.

In Trillium Diagnostik, Dr. Felicitas Mungenast and Alexander Stickler-Barang highlight the role of immunophenotyping in tissue sections for diagnosing diseases. The full article is available in German.

As AI moves beyond hype, it is shaping biomedical research and clinical practice. In our Dossier on AI in Biomedicine, experts explore current applications, challenges, and how AI could transform healthcare by 2050.