IF Skin Morphology
Segment epidermis and dermis in skin tissues, segment cells into nucleus, perinuclear area, and/or cytoplasm, define phenotypes of stained populations, classify cells inside/outside structures.
dermatology, epidermis, dermis, skin, fluorescence
The IF Skin Morphology App provides tissue detection including segmentation into epidermis and dermis based on specific IF staining. It segments the cells into nucleus, and/or perinuclear area and/or cytoplasm and determines the cellular phenotype of specific IF stained cell populations. The detected cells can be classified and visualized as being either within or outside of detected structures (epidermis and dermis). Each segmented cell compartment is measured for up to 20 intensity, statistics and morphometric parameters which can be displayed in diagrams and exported. Image Courtesy: Hosana Rodrigues, State University of Campinas
Hosana Rodrigues, State University of Campinas
Original Image
Dermis detection
Epidermis detection
Dermis/epidermis/nuclei detection
Webinar
21 Oct, 2025
Multimodal Imaging of Cellular Senescence: Tissue Cytometry and Beyond
Webinar
21 Oct, 2025
Multimodal Imaging of Cellular Senescence: Tissue Cytometry and Beyond
White Paper
17 Oct, 2025
Integrative Multiomics Approach Unveils Systemic Dysfunction in Colorectal Cancer (CRC)
Blog Post
17 May, 2023
An Intro to Deep Learning in Biomedical Imaging
We support the following file formats:
- TissueFAXS (aqproj)
- StrataFAXS II (vmic)
- PreciPoint (vmic, gtif)
- Generic BigTIFF Import
- Support for multipage BigTIFF files
- OME-TIFF
- JPEG, PNG, BMP, TIFF
- Zeiss (czi)
- Hamamatsu NanoZoomer (ndpi)
- Aperio (svs)
- Leica (scn)
- 3D HISTECH Pannoramic
- Mirax (mrxs)
- Olympus (vsi)
- More slide scanners to be added!
Related Apps
IF Artificial Skin
Stratify skin equivalents into dermis and epidermis, segment the stratum corneum, high/low suprabasal and basal layers, and quantify staining intensity, area, nuclei, and number/% of marker-positive cells for each layer.
dermatology, epidermis, dermis, skin, aging, oxidative UV damage, artificial skin
IF Immune status in situ
Characterize immune cell phenotypes relative to detected metastructures (e.g. tumors, glands), define distance ranges, measure cell-to-boundary distances inside/outside, and export up to 20 intensity, statistic, and morphometric parameters per cell compartment.
colon cancer, cytotoxic t cells, tumor microenvironment, PD1, CD8, spatial analysis, fluorescence
Custom App development
Perfectly tailored image analysis solutions for your research.
You have a specific research question that needs to be answered? We offer custom development of image analysis pipelines for specific tasks, be it detection of cellular phenotypes or quantification of tissue structures. After discussing your goals with one of our experts, you will get a ready-to-use App and be a step closer to an impactful publication.
