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IHC Angio

Detect blood vessels based on appropriate stains (e.g. CD31), measure vessel and lumen areas, and export vessel number, density, and areas of vessels, endothelium, and lumina.

blood vessels, tumor vascularization, tumor microenvironment, brightfield

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The IHC Angio App detects blood vessels based on appropriate stains (e.g. CD31) and measures overall vessel area as well as lumen area. The vessel detection also can be set to close open stained vessel walls and to connect separated vessel sections within a definable distance. The APP outputs number and vessel density as well as areas of vessels, endothelium and lumina.

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Original image

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Endothelial cell detection

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Vessel lumen detection

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Blood vessel detection

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Application Note

01 Jun, 2023

Evaluating the Distance of Tumor Cells from Blood Vessels

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White Paper

17 Oct, 2025

Integrative Multiomics Approach Unveils Systemic Dysfunction in Colorectal Cancer (CRC)

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Blog Post

17 May, 2023

An Intro to Deep Learning in Biomedical Imaging

We support the following file formats:

  • TissueFAXS (aqproj)
  • StrataFAXS II (vmic)
  • PreciPoint (vmic, gtif)
  • Generic BigTIFF Import
  • Support for multipage BigTIFF files
  • OME-TIFF
  • JPEG, PNG, BMP, TIFF
  • Zeiss (czi)

  • Hamamatsu NanoZoomer (ndpi)
  • Aperio (svs)
  • Leica (scn)
  • 3D HISTECH Pannoramic
  • Mirax (mrxs)
  • Olympus (vsi)
  • More slide scanners to be added!

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IF Tumor Vascularization

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IHC Tumor Vascularization

Segment tissue into tumor and healthy/stromal regions, detect blood vessels (e.g., CD31), and quantify vessel number, area, density, and connectivity within each compartment.

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Image

Custom App development

Perfectly tailored image analysis solutions for your research.

You have a specific research question that needs to be answered? We offer custom development of image analysis pipelines for specific tasks, be it detection of cellular phenotypes or quantification of tissue structures. After discussing your goals with one of our experts, you will get a ready-to-use App and be a step closer to an impactful publication.

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About Us

TissueGnostics provides advanced solutions for whole-slide imaging and image analysis in biological and clinical research. Our products help researchers to scan and analyze complex tissue samples, enabling more detailed insights into tissue structure, cellular interactions, and spatial cell landscape.

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