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IF Insulin Islet

Detect insulin islets and whole tissue in IF samples, segment nuclei using deep learning, and quantify islet number, area, total cells, and marker-specific phenotypes in tissue and within islets.

insulin islets, pancreas, beta-cells

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The IF Insulin Islet App allows for detection marker stained insulin islets, the whole tissue, and cellular phenotypes stained by specific markers within the insulin islets. The App outputs, whole tissue area (µm2), number and area (µm2) of detected insulin islets. Number of cells and marker-specific phenotypes in the whole tissue as well as within the insulin islets.

Emma Hamilton-Williams, The University of Queensland, Australia

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Webinar

21 Oct, 2025

Multimodal Imaging of Cellular Senescence: Tissue Cytometry and Beyond

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White Paper

17 Oct, 2025

Integrative Multiomics Approach Unveils Systemic Dysfunction in Colorectal Cancer (CRC)

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Blog Post

17 May, 2023

An Intro to Deep Learning in Biomedical Imaging

We support the following file formats:

  • TissueFAXS (aqproj)
  • StrataFAXS II (vmic)
  • PreciPoint (vmic, gtif)
  • Generic BigTIFF Import
  • Support for multipage BigTIFF files
  • OME-TIFF
  • JPEG, PNG, BMP, TIFF
  • Zeiss (czi)

  • Hamamatsu NanoZoomer (ndpi)
  • Aperio (svs)
  • Leica (scn)
  • 3D HISTECH Pannoramic
  • Mirax (mrxs)
  • Olympus (vsi)
  • More slide scanners to be added!

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IHC Insulin Islets

The IHC Insulin Islet App detects marker-stained insulin islets, tissue area, and cell phenotypes within and outside the islets. Outputs include tissue and islet area, cell counts, and phenotype distribution.

metastructures

single-cell analysis

insulin islets, pancreas, beta-cells

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IF Granuloma

Detect granulomas using nuclear structure analysis and IF markers (e.g. CD11c, CD68), measure granuloma number, area, and density, and export up to 20 intensity, statistic, and morphometric parameters per cell compartment.

metastructures

immunophenotyping

dentritic cells, macrophages, inflammation, granulomas, mouse, liver, fluorescence, microeinvironment, immune cells

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IHC Membrane

Unmix up to three markers in IHC/HC slides, segment cells into nucleus, perinuclear area, cytoplasm, and membrane (e.g. HER2/neu), measure up to 20 intensity, statistic, and morphometric parameters per compartment plus membrane intensity and angle.

intracellular analysis

single-cell analysis

tumor microenvironment

HER2, breast cancer, immunohistochemistry, automated scoring

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Custom App development

Perfectly tailored image analysis solutions for your research.

You have a specific research question that needs to be answered? We offer custom development of image analysis pipelines for specific tasks, be it detection of cellular phenotypes or quantification of tissue structures. After discussing your goals with one of our experts, you will get a ready-to-use App and be a step closer to an impactful publication.

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About Us

TissueGnostics provides advanced solutions for whole-slide imaging and image analysis in biological and clinical research. Our products help researchers to scan and analyze complex tissue samples, enabling more detailed insights into tissue structure, cellular interactions, and spatial cell landscape.

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