Sirius Red Polarized
Quantify collagen type I (red) and type III (green) fibers in Sirius Red–stained polarized images, measuring region area and the area of red, green, and overlapping (double-positive) fibers.
metastructures
vascularization
sirius red, collagen I, collagen III, polarized light, fibres
The Sirius Red Polarized App allows for quantification of collagen type I and type III based on Sirius Red Staining imaged with polarized light. It outputs the region area (µm2), the area of collagen type I = red fibres (µm2), collagen type III = green fibres (µm2) and overlapping fibres (µm2).
Image courtesy of Dr. Mortiz Uhlig, University Hospital RWTH Aachen
Detection of collagen type I
Detection of collagen type III
Overlapping of collagen type I and III
vascularization
Application Note
01 Jun, 2023
Evaluating the Distance of Tumor Cells from Blood Vessels
metastructures
Blog Post
17 May, 2023
An Intro to Deep Learning in Biomedical Imaging
We support the following file formats:
- TissueFAXS (aqproj)
- StrataFAXS II (vmic)
- PreciPoint (vmic, gtif)
- Generic BigTIFF Import
- Support for multipage BigTIFF files
- OME-TIFF
- JPEG, PNG, BMP, TIFF
- Zeiss (czi)
- Hamamatsu NanoZoomer (ndpi)
- Aperio (svs)
- Leica (scn)
- 3D HISTECH Pannoramic
- Mirax (mrxs)
- Olympus (vsi)
- More slide scanners to be added!
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Custom App development
Perfectly tailored image analysis solutions for your research.
You have a specific research question that needs to be answered? We offer custom development of image analysis pipelines for specific tasks, be it detection of cellular phenotypes or quantification of tissue structures. After discussing your goals with one of our experts, you will get a ready-to-use App and be a step closer to an impactful publication.
