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IHC Macrophages

Detect macrophages in IHC samples, apply area and distance-range algorithms to measure Langerhans cell distances to the epidermis border inside/outside, and export up to 20 parameters per cell compartment plus boundary distance.

metastructures

single-cell analysis

immunophenotyping

immune cells, brightfield, macrophages, immunohistochemistry, epidermis, langerhans cells, dermatology, CD68

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The IHC Macrophages App detects macrophages based on adequately stained IHC samples (e.g. CD68). The App further proves area detection and distance range algorithms to determine the distance of Langerhans cells from the border of the epidermis within and without. Each segmented cell compartment is measured for up to 20 parameters, as is the distance of each cell to the boundary.

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Original image

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Nuclei and marker detection

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Dermis and epidermis detection

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Combined detection

immunophenotyping

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Webinar

20 Jan, 2026

Decoding Metastatic Potential in Colorectal Cancer Using Tissue Cytometry

single-cell analysis

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White Paper

30 Mar, 2026

Understanding NeuroCOVID-19: SARS-CoV-2 Disrupts Astrocyte Homeostatic Functions

metastructures

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Blog Post

17 May, 2023

An Intro to Deep Learning in Biomedical Imaging

We support the following file formats:

  • TissueFAXS (aqproj)
  • StrataFAXS II (vmic)
  • PreciPoint (vmic, gtif)
  • Generic BigTIFF Import
  • Support for multipage BigTIFF files
  • OME-TIFF
  • JPEG, PNG, BMP, TIFF
  • Zeiss (czi)

  • Hamamatsu NanoZoomer (ndpi)
  • Aperio (svs)
  • Leica (scn)
  • 3D HISTECH Pannoramic
  • Mirax (mrxs)
  • Olympus (vsi)
  • More slide scanners to be added!

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IHC Tumor Macrophages

Segment tissue into tumor and healthy areas, detect CD68+ macrophages, and quantify macrophage area within each tissue compartment.

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single-cell analysis

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Image

Custom App development

Perfectly tailored image analysis solutions for your research.

You have a specific research question that needs to be answered? We offer custom development of image analysis pipelines for specific tasks, be it detection of cellular phenotypes or quantification of tissue structures. After discussing your goals with one of our experts, you will get a ready-to-use App and be a step closer to an impactful publication.

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+43 1 216 11 90
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About Us

TissueGnostics provides advanced solutions for whole-slide imaging and image analysis in biological and clinical research. Our products help researchers to scan and analyze complex tissue samples, enabling more detailed insights into tissue structure, cellular interactions, and spatial cell landscape.

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