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HE Alveoli Hamster

Detect nuclei and alveoli in HE-stained lung sections, classify alveoli into user-defined size ranges, and quantify tissue area, total alveoli area, and number/% per size class. Adaptable to other species.

brightfield

metastructures

hamster, rodents, H&E, lung, aveoli, pneumology

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The HE Aveoli Hamster App provides detection of nuclei, aveoli, and the categorization of aveoli in user defined size classes (e.g. 0-1000µm2, 1000-8000µm2, 8000-15000µm2) in HE stained tissue sections. It outputs total tissue area (µm2), total aveoli area (µm2), number and % of aveoli for user-defined size classes. This App can be easily adapted to tissues of other species such as mouse or rat.

Image courtesy of Marc Scott, TRI, Queensland University

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Original Image

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Detection of nuclei

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Detection of alveoli

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Combined detection

metastructures

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Blog Post

17 May, 2023

An Intro to Deep Learning in Biomedical Imaging

We support the following file formats:

  • TissueFAXS (aqproj)
  • StrataFAXS II (vmic)
  • PreciPoint (vmic, gtif)
  • Generic BigTIFF Import
  • Support for multipage BigTIFF files
  • OME-TIFF
  • JPEG, PNG, BMP, TIFF
  • Zeiss (czi)

  • Hamamatsu NanoZoomer (ndpi)
  • Aperio (svs)
  • Leica (scn)
  • 3D HISTECH Pannoramic
  • Mirax (mrxs)
  • Olympus (vsi)
  • More slide scanners to be added!

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IHC Lung Cancer Mouse

Segment murine lung sections into tumor and non-cancerous tissue using a machine learning classifier, detect hematoxylin-stained nuclei, and quantify tumor area and marker-positive cellular phenotypes.

metastructures

single-cell analysis

tumor microenvironment

immunohistochemistry, lung cancer, tumor microenvironment, mouse, lung

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Pulmo

Segment nuclei and lung metastructures (total tissue, bronchioles, vessels, alveoli), detect cellular phenotypes within each component, and measure up to 20 morphometric parameters per metastructure and nucleus.

metastructures

single-cell analysis

immunophenotyping

lung cancer, lung anatomy, bronchioles, blood vessels, alveoles, immunohistochemistry, neutrophiles, brightfield

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Custom App development

Perfectly tailored image analysis solutions for your research.

You have a specific research question that needs to be answered? We offer custom development of image analysis pipelines for specific tasks, be it detection of cellular phenotypes or quantification of tissue structures. After discussing your goals with one of our experts, you will get a ready-to-use App and be a step closer to an impactful publication.

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TissueGnostics GmbH
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About Us

TissueGnostics provides advanced solutions for whole-slide imaging and image analysis in biological and clinical research. Our products help researchers to scan and analyze complex tissue samples, enabling more detailed insights into tissue structure, cellular interactions, and spatial cell landscape.

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