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On May 3rd, TissueGnostics surpassed 1,500 scientific reference publications

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 Most of the 1500 research publications referencing TissueGnostics (over 50%) originated in the United States, Austria, Germany, Taiwan (China) and mainland China.

  

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Customer Publications (A total of 1522 papers published)

401
Afatinib restrains K-RAS–driven lung tumorigenesis

Herwig P. Moll, Klemens Pranz, Monica Musteanu, Beatrice Grabner, Natascha Hruschka, Julian Mohrherr

Science Translational Medicine (American Association for the Advancement of Science) Austria, 20 June 2018

Oncology

Key words: Afatinib, K-RAS, lung cancer, pan-ERBB, tyrosine kinase inhibitors

Organism: Mouse

Tissue: Lung

Pathological State: Cancer

402
Competition between TIAM1 and Membranes Balances Endophilin A3 Activity in Cancer Metastasis

Kumud R.Poudel MinnaRoh-Johnson AllenSu ThuongHo HarithaMathsyaraja SarahAnderson William M.Grady Cecilia B.Moens MaraliceConacci-Sorrell Robert N.Eisenman

Developmental Cell (Cell Press) USA, 18 June 2018

Oncology

Key words: BAR domain; PTEN; Rac1; TIAM1; cell migration; endocytosis; endophilin; membrane remodeling; metastasis

Organism: Mouse

Tissue: Whole Organism

Pathological State: Cancer

403
Endothelial colony forming cells from human umbilical cord blood improved severe erectile dysfunction in obese type II diabetic rats

Abrar Al-Mahmood Siddiqueea , P. Ganesan Adaikana, , Lang Chu Laua , Baharudin Bin Saida , Mark Chongb , Jerry Chanc , Swee Hin Teoh

Life Science (Elsevier) Singapore, 18 June 2018

Reproductive Medicine

Key words: Severe erectile dysfunction, Human endothelial colony forming cells, Intracavernosal pressure, Zucker diabetic fatty rats

Organism: Rat

Tissue: Penis

Pathological State: Erectile dysfunction

404
Quantitative measurement of breast carcinoma fibrosis for the prediction in the risk of bone metastasis

Chong Sun, Bin Wang, Jianmin Li, Junjie Shangguan, Matteo Figini, Kang Zhou, Liang Pan, Quanhong Ma, Zhuoli Zhang

American Journal of Translational Research (e-Century Publishing Corporation) China, 15 June 2018

Oncology

Key words: Invasive breast carcinoma; bone metastasis; collagen deposition; early prediction

Organism: Human

Tissue: Breast

Pathological State: Cancer

405
Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles

Sander C Steenbeek, Thang V Pham, Joep de Ligt, Anoek Zomer, Jaco C Knol, Sander R Piersma, Tim Schelfhorst, Rick Huisjes, Raymond M Schiffelers, Edwin Cuppen, Connie R Jimenez, Jacco van Rheenen

EMBO Journal (EMBO press) The Netherlands, 15 June 2018

Oncology

Key words: Cre‐LoxP; extracellular vesicles; intratumoral heterogeneity; intravital microscopy; signaling networks

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

406
Substance P modulates bone remodeling properties of murine osteoblasts and osteoclasts

Tanja Niedermair, Stephan Schirner, Raphael Seebröker, Rainer H. Straub, Susanne Grässel

Scientific Reports (Nature) Germany, 15 June 2018

Physiology

Key words: Substance P, bone remodeling, osteoblasts, osteoclasts, Bone, Mechanisms of disease

Organism: Mouse

Cell Line: Osteoclast, Osteoblast

407
Synergistic Antitumor Effect of Oligogalacturonides and Cisplatin on Human Lung Cancer A549 Cells

Cian-Song Huang, Ai-Chun Huang, Ping-Hsiu Huang, Diana Lo, Yuh-Tai Wang, Ming-Chang Wu

International Journal of Molecular Sciences (MDPI) Taiwan, 14 June 2018

Oncology

Key words: adjuvant therapy; cisplatin; oligogalacturonides; synergistic effect

Organism: Human

Pathological State: Cancer

Cell Line: A549 (Lung carcinoma cells)

408
Nerve Growth Factor (NGF)—Receptor Survival Axis in Head and Neck Squamous Cell Carcinoma

József Dudás, Wolfgang Dietl, Angela Romani, Susanne Reinold, Rudolf Glueckert, Anneliese Schrott-Fischer, Daniel Dejaco, Lejo Johnson Chacko, Raphaela Tuertscher, Volker Hans Schartinger, Herbert Riechelmann

International Journal of Molecular Sciences (MDPI) Austria, 14 June 2018

Oncology

Key words: TissueFaxs; cell cycle arrest; cytokeratin; necrosis

Organism: Human

Tissue: Mucosa

Pathological State: Cancer

409
Breast Cancer Histological Image Classification Using Fine-Tuned Deep Network Fusion

A Mahbod, I Ellinger, R Ecker, Ö Smedby, C Wang

(Springer) , 06 June 2018

Key words: Breast cancer Histological images Classification Deep learning

410
Targeted intracerebral delivery of the anti-inflammatory cytokine IL13 promotes alternative activation of both microglia and macrophages after stroke

Somayyeh Hamzei Taj, Debbie Le Blon, Chloé Hoornaert, Jasmijn Daans, Alessandra Quarta, Jelle Praet, Annemie Van der Linden, Peter Ponsaerts, Mathias Hoehn

Journal of Neuroinflammation (Springer) Germany, 04 June 2018

Immunology

Key words: Interleukin 13; Mesenchymal stem cells; Microglia/macrophage polarization; Neuroinflammation; Stroke

Organism: Mouse

Tissue: Brain

Pathological State: Cerebral Ischemia

411
Novel Conducting and Biodegradable Copolymers with Noncytotoxic Properties toward Embryonic Stem Cells

Aruã C. da Silva, Ana Teresa S. Semeano, André H. B. Dourado, Henning Ulrich, Susana I. Cordoba de Torresi

ACS OMEGA (ACS Publications) Brazil, 31 May 2018

Stem Cell Research

Key words: Cell and Molecular biology; Conducting polymers; Environmental biology; Polyesters

Organism: Human

Cell Line: Human embryonic stem cells (hESCs)

412
Hierarchical Multiplexing Nanodroplets for Imaging-Guided Cancer Radiotherapy via DNA Damage Enhancement and Concomitant DNA Repair Prevention

Wei Jiang, Quan Li, Liang Xiao, Jiaxiang Dou, Yi Liu, Wenhao Yu, Yinchu Ma, Xiaoqiu Li, Ye-Zi You, Zhuting Tong, Hang Liu, Hui Liang, Ligong Lu, Xiaoding Xu, Yandan Yao, Guoqing Zhang, Yucai Wang, and Jun Wang

ACS NANO (ACS Publications) China, 29 May 2018

Nanomedicine

Key words: cancer radiotherapy; DNA damage and repair; hierarchical nanostructure; multimodal imaging; tumor hypoxia

Organism: Mouse

Tissue: Allograft Tumor

Pathological State: Cancer

413
Acellular vascular matrix grafts from human placenta chorion: Impact of ECM preservation on graft characteristics, protein composition and in vivo performance

Karl H. Schneider, Marjan Enayati, Christian Grasl, Ingrid Walter, Lubos Budinsky, Gabriel Zebic, Christoph Kaun, Anja Wagner, Klaus Kratochwill, Heinz Redl, Andreas Teuschl, Bruno K. Podesser, Helga Bergmeister

Biomaterials (Elsevier) Austria, 29 May 2018

Regenerative Medicine

Key words: Decellularized matrix, Human placenta, Small diameter vascular grafts, Cell migration, Biocompatibility

Organism: Human

Tissue: Placenta

414
Identification of galectin-3 as an autoantigen in patients with IgG4-related disease

Cory A. Perugino, DO,a,b* Sultan B. AlSalem, MBBS, MMSc,b,c* Hamid Mattoo, PhD,b Emanuel Della-Torre, MD, PhD,b,d Vinay Mahajan, Gayathri Ganesh, Hugues Allard-Chamard, Zachary Wallace, Sydney B. Montesi, Johannes Kreuzer, Wilhelm Haas, John H. Stone, Shiv Pillai

Journal of Allergy and Clinical Immunology (Elsevier) UK, USA, Italy, 29 May 2018

Immunology

Key words: IgG4-related disease, plasmablast, autoantigen, galectin-3, autoantibody

Organism: Human

Tissue: Pancreas

Pathological State: IgG4-Related Disease

415
Allocation of Interferon Gamma mRNA Positive Cells in Caecum Hallmarks a Protective Trait Against Histomonosis

Fana Alem Kidane, Taniya Mitra, Patricia Wernsdorf, Michael Hess, Dieter Liebhart

Frontiers in Immunology (Frontiers Media S.A.) Austria, 28 May 2018

Immunology

Key words: Histomonas meleagridis; histomonosis; image analysis; immunofluorescence; in situ hybridization; interferon gamma; interleukin-13; vaccination

Organism: Turkey, Chicken

Tissue: Small Intestine, Liver, Spleen

Pathological State: Parasitic Infection

416
The overexpression of Fra1 disorders the inflammatory cytokine secretion by mTEC of myasthenia gravis thymus

Q.‐R. Li W.‐P. Ni N.‐J. Lei J.‐Y. Yang X.‐Y. Xuan P.‐P. Liu G.‐M. Gong F. Yan Y.‐S. Feng R. Zhao Y. Du

Scandinavian journal of Immunology (Blackwell Publishing Inc.) China, 28 May 2018

Neuroscience

Key words: Fos-related antigen-1; inflammatory cytokine; medulla thymic epithelial cells; myasthenia gravis

Organism: Human

Tissue: Thymus

Pathological State: Myasthenia Gravis

417
Therapeutic effects of dietary intervention on neuroinflammation and brain metabolism in a rat model of photothrombotic stroke

Ewelina Kurtys Cindy Casteels Caroline C. Real Ulrich L. M. Eisel J. Martin Verkuyl Laus M. Broersen Hans C. Klein Rudi A. J. O. Dierckx Janine Doorduin Erik F. J. de Vries

CNS Neuroscience and Therapeutics (Wiley) The Netherlands, 27 May 2018

Neuroscience

Key words: PET imaging; neuroinflammation; nutrition; photothrombotic stroke

Organism: Rat

Tissue: Brain

Pathological State: Cerebral Ischemia

418
Decreased argininosuccinate synthetase expression in Thai patients with cholangiocarcinoma and the effects of ADI-PEG20 treatment in CCA cell lines

Somphon Roeksomtawin, Panida Navasumrit, Somchamai Waraprasit, Varabhorn Parnlob, Thaniya Sricharunrat, Vajarabhongsa Bhudhisawasdi, Niramol Savaraj, Mathuros Ruchirawat

Oncology Letters (Spandidos Publications) Thailand, 24 May 2018

Oncology

Key words: Ki-67; arginine deprivation; argininosuccinate synthetase; cholangiocarcinoma; pegylated arginine deiminase

Organism: Human

Tissue: Liver

Pathological State: Cancer

Cell Line: Cholangiocarcinoma cell lines (RmCCA-1 and HuCCA), human fibroblast cell line (BJ-1)

419
Cordycepin induces apoptosis of human ovarian cancer cells by inhibiting CCL5-mediated Akt/NF-κB signaling pathway

Zhen Yang Cui, Soo Jung Park, Eunbi Jo, In-Hu Hwang, Kyung-Bok Lee, Sung-Woo Kim, Dae Joon Kim, Jong Chun Joo, Seok Hoon Hong, Min-Goo Lee and Ik-Soon Jang

Cell Death Discovery (Nature) South Korea, USA, 23 May 2018

Oncology

Organism: Human

Pathological State: Cancer

Cell Line: SKOV-3 cells

420
BMP-2 restoration aids in recovery from liver fibrosis by attenuating TGF-β1 signaling

Yueh-Hua Chung, Ying-Hsien Huang, Tien-Huei Chu, Chun-Lin Chen, Pey-Ru Lin, Shih-Chung Huang, Deng-Chyang Wu, Chao-Cheng Huang, Tsung-Hui Hu, Ying-Hsien Kao and Ming-Hong Tai

Laboratory Investigation (Nature) Taiwan, 22 May 2018

Hepathology

Key words: BMP-2, liver fibrosis, TGF-β1 signaling

Organism: Human

Tissue: Liver

Pathological State: Hepatitis, Liver Cirrhosis

421
Kinin and Purine Signaling Contributes to Neuroblastoma Metastasis

Henning Ulrich, Mariusz Z. Ratajczak, Gabriela Schneider, Elena Adinolfi, Elisa Orioli, Enéas G. Ferrazoli, Talita Glaser, Juliana Corrêa-Velloso, Poliana C. M. Martins, Fernanda Coutinho, Ana P. J. Santos, Micheli M. Pillat, Ulrich Sack, Claudiana Lameu

Frontiers in Pharmacology (Frontiers Media S.A.) Brazil, 18 May 2018

Oncology

Key words: bone marrow; bradykinin; metastasis; neuroblastoma; purinergic system

Organism: Human

Pathological State: Cancer

Cell Line: CHP-100 cells

422
Lactobacillus casei Variety rhamnosus Probiotic Preventively Attenuates 5-Fluorouracil/Oxaliplatin-Induced Intestinal Injury in a Syngeneic Colorectal Cancer Model

Ching-Wei Chang, Chia-Yuan Liu, Hung-Chang Lee, Yen-Hua Huang, Li-Hui Li, Jen-Shiu Chiang Chiau, Tsang-En Wang, Cheng-Hsin Chu, Shou-Chuan Shih, Tung-Hu Tsai, Yu-Jen Chen

Frontiers in Microbiology (Frontiers Media S.A.) Taiwan, 15 May 2018

Oncology

Key words: FOLFOX; Lactobacillus; apoptosis; gut microbiota; intestinal mucositis

Organism: Mouse

Tissue: Allograft Tumor

Pathological State: Cancer

423
Catalpol inhibits migration and induces apoptosis in gastric cancer cells and in athymic nude mice

Zheng-HuaWangZhan-ShengHu

Biomedicine and Pharmacotherapy (Elsevier) China, 14 May 2018

Oncology

Key words: Gastric cancer, Catalpol, Migration, Apoptosis and ROS, DDP

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

424
A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment

Amelie Griveau, GiorgioS eano, Samuel J. Shelton, Robert Kupp, Arman Jahangiri, Kirsten Obernier, Shanmugarajan Krishnan, Olle R. Lindberg, Tracy J. Yuen, An-Chi Tien, Jennifer K.Sabo, Nancy Wang, Ivy Chen, Jona sKloepper, Louis Larrouquere, Mitrajit Ghosh, Itay Tirosh, Emmanuelle Huillard, Arturo Alvarez-Buylla, Michael C. Oldham, Anders I. Persson, William A. Weiss, Tracy T. Batchelor, Anat Stemmer-Rachamimov, Mario L.Suvà, Joanna J. Phillips, Manish K .Aghi, Shwetal Mehta, Rakesh K. Jain, David H. Rowitch

Cancer Cell (Cell Press) USA, 14 May 2018

Oncology

Key words: Olig2; Wnt; angiogenesis; astrocyte; blood-brain barrier; glioma; invasiveness; oligodendrocyte precursor; p53; vessel co-option

Organism: Human, Mouse

Tissue: Brain, Xenograft Tumor

Pathological State: Cancer

425
Hematological findings in non-treated and gamma-irradiated mice deficient for MIC-1/GDF15.

M. HOFER, Z. HOFEROVÁ, J. REMŠÍK, M. NOVÁKOVÁ, J. PROCHÁZKOVÁ, R. FEDR, J. KOHOUTEK, L. DUŠEK, A. HAMPL, K. SOUČEK

Physiological Research (BioMed Central) Czech Republic, 10 May 2018

Hematology

Key words: GDF15 knockout mice; hematopoiesis; ionizing radiation; stress-induced cytokine

Organism: Mouse

Tissue: Spleen, Bone

426
DNA damage predicts prognosis and treatment response in colorectal liver metastases superior to immunogenic cell death and T cells

Johannes Laengle, Judith Stift, Agnes Bilecz, Brigitte Wolf, Andrea Beer, Balazs Hegedus, Stefan Stremitzer, Patrick Starlinger, Dietmar Tamandl, Dietmar Pils, Michael Bergmann

Theranostics (Ivyspring International Publisher) Austria, 10 May 2018

Oncology

Key words: DNA damage, calreticulin, immunogenic cell death, colorectal liver metastases

Organism: Human

Tissue: Colon

Pathological State: Cancer

427
Regorafenib inhibits tumor progression through suppression of ERK/NF-κB activation in hepatocellular carcinoma bearing mice

Mao-Chi Weng, Mei-Hui Wang, Jai-Jen Tsai, Yu-Cheng Kuo, Yu-Chang Liu, Fei-Ting Hsu, Hsin-Ell Wang

Bioscience Reports (Kluwer Academic Publishers) Taiwan, 05 May 2018

Oncology

Key words: Bioluminescence imaging; Regorafenib; apoptosis; hepatocellular carcinoma; nuclear factor kappaB

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

428
Effects of chitosan and chitosan N-acetylcysteine solutions on conjunctival epithelial cells

N Schuerer, E Stein, A Inic-Kanada, E Ghasemian, Marijana Stojanovic, Jacqueline Montanaro, Nora Bintner, Christine Hohenadl, Robert Sachsenhofer, Talin Barisani-Asenbauera

Journal of EuCornea (Elsevier) Austria, Serbia, 02 May 2018

Ophthalmology

Key words: Chitosan Chitosan-N-acetylcysteine Uptake Conjunctival epithelial cells Drug delivery

Organism: Guinea Pig

Tissue: Eye

429
Rab37 in lung cancer mediates exocytosis of soluble ST2 and thus skews macrophages toward tumor‐suppressing phenotype

Hong‐Tai Tzeng Ching‐Chin Su Chih‐Peng Chang Wu‐Wei Lai Wu‐Chou Su Yi‐Ching Wang

International journal of cancer (Wiley) Taiwan, 01 May 2018

Oncology

Key words: Rab37; ST2; exocytosis; macrophage; tumor microenvironment

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

430
Blimp-1 prolongs allograft survival without regimen via influencing T cell development in favor of regulatory T cells while suppressing Th1

Aline Yen LingWanga Charles Yuen YungLoh Shyi-JouChen Huang-KaiKao Cheng-HungLin Sheng-HaoChuang Chin-MingLee Huey-KangSytwu Fu-ChanWei

Molecular Immunology (Elsevier) Taiwan, 23 April 2018

Immunology

Key words: Allograft tolerance, B lymphocyte-induced maturation protein, T cells

Organism: Mouse

Tissue: Skin

Pathological State: Organ Transplantation

431
Eupatilin inhibits the proliferation of human esophageal cancer TE1 cells by targeting the Akt‑GSK3β and MAPK/ERK signaling cascades

Xiaona Wang Yanyan Zhu Lili Zhu Xinhuan Chen Yanyan Xu Yafei Zhao Yingzhe Shao Feng Li Yanan Jiang Jing Lu Youtian Huang Xiaobin Chang Juan Zhang Xiang Li Kangdong Liu Mingyao Zhao Ziming Dong Jimin Zhao

Oncology Reports (Demetrios A. Spandidos Ed. and Pub.) China, 23 April 2018

Oncology

Key words: Eupatilin, human esophageal cancer, TE1 cells, Akt‑GSK3β, MAPK/ERK

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

432
IL-33/ST2 axis mediates hyperplasia of intrarenal urothelium in obstructive renal injury

Wei-Yu Chen, Jenq-Lin Yang, Yi-Hsiu Wu, Lung-Chih Li, Ru-Fang Li, Ya-Ting Chang, Lo-Hsin Dai, Wan-Chen Wang, Ya-Jen Chang

Experimental and Molecular Medicine (Nature) Taiwan, 20 April 2018

Nephrology

Key words: IL-33/ST2 axis, hyperplasia, renal injury, unilateral ureteral obstruction (UUO)

Organism: Mouse

Tissue: Kidney

Pathological State: Kidney Injury

433
Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal

Samra Turajlic, Hang Xu, Kevin Litchfield, Andrew Rowan, Stuart Horswell, Tim Chambers

CELL (Cell Press) UK, 19 April 2018

Oncology

Key words: branched evolution; cancer evolution; chromosome instability; deterministic evolution; intratumor heterogeneity; linear evolution; metastasis; punctuated evolution; renal cell cancer; tumor diversity

Organism: Human

Tissue: Kidney

Pathological State: Cancer

434
Tumor-induced generation of splenic erythroblast-like Ter-cells promotes tumor progression

Han Y, Liu Q, Hou J, Gu Y, Zhang Y, Chen Z, Fan J, Zhou W, Qiu S, Zhang Y, Dong T, Li N, Jiang Z, Zhu H, Zhang Q, Ma Y, Zhang Q, Wang Q, Yu Y, Li N, Cao X

CELL (Cell Press) China, 19 April 2018

Oncology

Key words: Ter-119; Ter-cell; artemin; cancer immunotherapy; erythroblast-like; hepatocellular carcinoma; prognosis biomarker

Organism: Mouse

Tissue: Liver

Pathological State: Cancer

435
Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal

Samra Turajlic, Hang Xu, Kevin Litchfield, Andrew Rowan, Tim Chambers, Jose I. Lopez, David Nicol

CELL (Cell Press) UK, 19 April 2018

Oncology

Key words: chromosome instability; cytoreductive nephrectomy; evolution of metastasis; loss of 9p; metastasectomy; metastasis; oligometastasis; renal cell cancer; solitary metastasis

Organism: Human

Tissue: Kidney

Pathological State: Cancer

436
Conditional depletion of GSK3b protects oligodendrocytes from apoptosis and lessens demyelination in the acute cuprizone model

Bin Xing Lauren E. Brink Kelly Maers Mara L. Sullivan Richard J. Bodnar Donna B. Stolz Franca Cambi

GLIA (Wiley) USA, 18 April 2018

Neuroscience

Key words: GSK3b; cell death; glia; multiple sclerosis

Organism: Mouse

Tissue: Brain

437
CD10 inhibits cell motility but expression is associated with advanced stage disease in colorectal cancer

Teresa P.RaposoabMireia SuecaComescAdeyemiIdowuaBoraAgitaJamesHassallabWakkasFadhilabRobertNicadRupertEckerdTakashiYaoeMohammadIlyas

Experimental and Molecular Pathology (Elsevier) UK, 11 April 2018

Oncology

Key words: CD10, NEP, CALLA, Colorectal cancer, Epithelial-mesenchymal transition, Metastasis

Organism: Human

Tissue: Colon

Pathological State: Cancer

438
Increased HOXA5 expression provides a selective advantage for gain of whole chromosome 7 in IDH wild-type glioblastoma

Patrick J. Cimino Youngmi Kim Hua-Jun Wu Jes Alexander, Hans-Georg Wirsching Frank Szulzewsky,1 Ken Pitter,7 Tatsuya Ozawa,1,8 Jiguang Wang,9,10,16 Julio Vazquez,11 Sonali Arora,1 Raul Rabadan Ross Levine Franziska Michor and Eric C. Holland

Genes and Development (Cold Spring Harbor Laboratory Press) USA, 09 April 2018

Oncology

Key words: glioblastoma, HoxA, homeobox RCAS, chromosome 7 gain

Organism: Mouse

Tissue: Brain

Pathological State: Cancer

439
Photodynamic Effect of Methylene Blue and Low Level Laser Radiation in Head and Neck Squamous Cell Carcinoma Cell Lines

Barbara Kofler, Angela Romani, Christian Pritz, Teresa Bernadette Steinbichler, Volker Hans Schartinger, Herbert Riechelmann, Jozsef Dudas

International Journal of Molecular Sciences (MDPI) Austria, 07 April 2018

Oncology

Key words: TissueFaxs; head and neck carcinoma; methylene blue; photodynamic therapy

Organism: Human

Pathological State: Cancer

Cell Line: Detroit 562 cells (pharynx carcinoma)

440
The expansion in lymphoid organs of IL-4+ BATF+ T follicular helper cells is linked to IgG4 class switching in vivo

Takashi Maehara, Hamid Mattoo, Vinay S Mahajan, Samuel JH Murphy, Grace J Yuen, Noriko Ishiguro, Miho Ohta, Masafumi Moriyama, Takako Saeki, Hidetaka Yamamoto, Masaki Yamauchi, Joe Daccache, Tamotsu Kiyoshima, Seiji Nakamura, John H Stone, Shiv Pillai

Life Science () USA, Japan, 05 April 2018

Immunology

Key words: T follicular helper (TFH), BATF+ ,IgG4 class switching, Sjögren’s syndrome,secondary lymphoid organs

Organism: Human

Tissue: Salivary Gland

441
Glycyrrhetinic Acid Antagonizes Pressure-Induced Venous Remodeling in Mice

Hanna Kuk,Caroline Arnold,Andreas H. Wagner,Markus Hecker,Carsten Sticht, and Thomas Korff

Frontiers in Physiology (Frontiers Media S.A.) Germany, 04 April 2018

Physiology

Key words: endothelial cells; spider veins; venous hypertension; venous remodeling; wall stress

Organism: Human

Cell Line: HUVEC, HUVSMC (human umbilical vein endothelial and SMCs)

442
Amentoflavone enhances the therapeutic efficacy of sorafenib by inhibiting anti-apoptotic potential and potentiating apoptosis in hepatocellular carcinoma in vivo

JJ Tsai, FT Hsu, PJ Pan, CW Chen, YC Kuo

Anticancer Research (International Institute of Anticancer Research) Taiwan, 01 April 2018

Oncology

Key words: Amentoflavone sorafenib hepatocellular carcinoma ERK AKT apoptosis

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

443
Cordyceps militaris Extract Inhibits the NF-κB pathway and Induces Apoptosis through MKK7-JNK Signaling Activation in TK-10 Human Renal Cell Carcinoma

SJ Park, HJ Jang, IH Hwang, JM Kim, E Jo, MG Lee, IS Jang, J Cheon Joo

Natural Product Communications (SAGE Journals) South Korea, 01 April 2018

Oncology

Key words: Cordyceps militaris, Apoptosis, NF-κB, MKK7, JNK, TK-10

Organism: Human

Pathological State: Cancer

Cell Line: TK-10 renal cancer cell lines

444
Periostin antisense oligonucleotide suppresses bleomycin‐induced formation of a lung premetastatic niche for melanoma

Takashi Semba Eiji Sugihara Nagisa Kamoshita Sayaka Ueno Keitaro Fukuda Masafumi Yoshino Kazumasa Takao Kazunori Yoshikawa Kenji Izuhara Yoshimi Arima Makoto Suzuki Hideyuki Saya

Cancer Science (Wiley) Japan, 31 March 2018

Oncology

Key words: antisense oligonucleotide; lung fibrosis; melanoma; periostin; premetastatic niche

Organism: Mouse

Tissue: Lung

445
MRI‐guided interventional natural killer cell delivery for liver tumor treatment

Zhanliang Su, Xifu Wang, Linfeng Zheng, Tianchu Lyu, Matteo Figini, Bin Wang, Daniel Procissi, Junjie Shangguan, Chong Sun, Liang Pan, Lei Qin, Bin Zhang, Yury Velichko, Riad Salem, Vahid Yaghmai, Andrew C. Larson, Zhuoli Zhang

Cancer Medicine (Wiley) USA, 30 March 2018

Oncology

Key words: Adoptive transfer immunotherapy; hepatocellular carcinoma; interventional oncology; magnetic resonance imaging; natural killer cell

Organism: Rat

Tissue: Liver

Pathological State: Cancer

446
Collagen morphology influences macrophage shape and marker expression in vitro

Gwenda F. Vasse, Philipp T. Kühn, Qihui Zhou, Shardul A. Bhusari, Catharina Reker-Smit, Barbro N. Melgert, Patrick van Rijn

Journal of Immunology and Regenerative Medicine (Elsevier) The Netherlands, 30 March 2018

Immunology

Key words: Extracellular matrix, Collagen type I, Pulmonary fibrosis, Ym1, CD206, Migration

Organism: Human

Cell Line: Alveolar-like Makrophhages

447
Olaparib is effective in combination with, and as maintenance therapy after, first‐line endocrine therapy in prostate cancer cells

Gertrud E. Feiersinger1,Kristina Trattnig1, Peter D. Leitner, Fabian Guggenberger,Alexander Oberhuber, Sarah Peer, Martin Hermann, Ira Skvortsova, Jana Vrbkova, Jan Bouchal, Zoran Culig and Fred eric R. Santer

Molecular Oncology (Wiley) Austria, 15 March 2018

Oncology

Key words: PARP inhibition; combination therapy; endocrine therapy; maintenance therapy; olaparib; prostate cancer

Organism: Human

Pathological State: Cancer

Cell Line: LNCaP-abl (Prostate carcinoma cell lines)

448
Loss of Neuroglobin Expression Alters Cdkn1a/Cdk6-Expression Resulting in Increased Proliferation of Neural Stem Cells

Evi Luyckx, Wendy Van Leuven, Daniel Andre, Alessandra Quarta, Kristien Reekmans, Erik Fransen, Luc Moens, Thomas Hankeln, Peter Ponsaerts, and Sylvia Dewilde

Stem Cells and Development (Mary Ann Liebert Inc.) Belgium, Germany, 15 March 2018

Stem Cell Research

Key words: neuroglobin – cell cycle – transcriptomics – neural stem cells

Organism: Mouse

Cell Line: Neural stem cells

449
Effects of iota-carrageenan on ocular Chlamydia trachomatis infection in vitro and in vivo

Aleksandra Inic-Kanada, Elisabeth Stein, Marijana Stojanovic, Nadine Schuerer, Ehsan Ghasemian, Ana Filipovic, Emilija Marinkovic, Dejana Kosanovic, Talin Barisani-Asenbauer

Journal of Applied Phycology (Kluwer Academic Publishers) Austria, 13 March 2018

Microbiology

Key words: Carrageenan, Trachoma, Natural products, Chlamydia

Organism: Human

Pathological State: Bacterial Infection

Cell Line: HCjE cells (human corneal-limbal and conjunctival epithelial cell line)

450
Prostaglandin E2 Is Required for BMP4-Induced Mesoderm Differentiation of Human Embryonic Stem Cells

Bowen Zhang,1,2,3 Lijuan He,1,2,3 Yiming Liu,1,2 Jing Zhang,1,2 Quan Zeng,1,2 Sihan Wang,1,2 Zeng Fan,1,2 Fang Fang Lin Chen Yang Lv Jiafei Xi Wen Yue Yanhua Li and Xuetao Pei

Stem Cell Reports (Cell Press) China, 13 March 2018

Stem Cell Research

Key words: prostaglandin E2, cyclooxygenase-1, BMP4, mesoderm, differentiation, human embryonic stem cells, β-catenin,

Organism: Human

Cell Line: WA01 and WA09 hESCs

451
Atlas of the Striatum and Globus Pallidus in the Tree Shrew: Comparison with Rat and Mouse

Rong-Jun Ni,Zhao-Huan Huang,Yu-Mian Shu,Yu Wang Tao Li, Jiang-Ning Zhou

Neuroscience Bulletin (Springer) China, 05 March 2018

Neuroscience

Key words: Striatum, Globus pallidus, Basal ganglia, Reconstruction, Rodent, Parvalbumin

Organism: Tree Shrew

Tissue: Brain

452
Novel platforms of multiplexed immunofluorescence for study of paraffin tumor tissues

Edwin Roger Parra

Journal of Cancer Treatment and Diagnosis () USA, 01 March 2018

Cytometry

Key words: Multiplexed proteins identification Immunofluorescence Signal Amplification Spatial Cell Distribution Image Analysis

453
4:20 PM Abstract No. 350 Interferon-gamma-eluting microspheres for MRI-guided immunotherapy of liver cancer

W.ParkA.GordonS.ChoX.HuangK.HarrisZ.ZhangA.LarsonD.Kim

Journal of Vascular and Interventional Radiology (Elsevier) USA, 01 March 2018

Oncology

Organism: Rabbit

Tissue: Liver

Pathological State: Cancer

454
In vitro behavior of human mesenchymal stem cells on poly(N-isopropylacrylamide) based biointerfaces obtained by matrix assisted pulsed laser evaporation

Madalina Icriverzi, Laurentiu Rusen, Livia Elena Sima, Antoniu Moldovan, Simona Brajnicov, Anca Bonciu, Natalia Mihailescu, Maria Dinescu, Anisoara Cimpean, Anca Roseanu, Valentina Dinca

Applied Surface Science (Elsevier) Romania, 28 February 2018

Cell Biology

Key words: pNIPAM coatings, MAPLE, mesenchymal stem cells

Organism: Human

Cell Line: Human mesenchymal stem cells (hMSCs)

455
CXCL5 facilitates melanoma cell-neutrophil interaction and lymph node metastasis

Ana Soler Cardona, Agnes Forsthuber, Katharina Lipp, Stefanie Ebersbergr, Magdalena Heinz, Klaudia Schossleitner, Elisabeth Buchberger, Mario Gröger, Peter Petzelbauer, Christoph Hoeller, Erwin Wagner, Robert Loewe

Journal of Investigative Dermatology (Elsevier) Austria, 21 February 2018

Dermatology

Key words: CXCL5, melanoma cells, chemokine mRNA expression

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

456
[18F]FEPPA: Improved Automated Radiosynthesis, Binding Affinity, and Preliminary in Vitro Evaluation in Colorectal Cancer

Neydher Berroterán-Infante, Theresa Balber, Petra Fürlinger, Michael Bergmann, Rupert Lanzenberger, Marcus Hacker, Markus Mitterhauser and Wolfgang Wadsak

ACS Medicinal Chemistry Letters (ACS Publications) Austria, 21 February 2018

Radiotherapy

Key words: Affinity, autoradiography, colorectal cancer, FEPPA, radiosynthesis, TSPO

Organism: Human

Tissue: Colon

Pathological State: Cancer

457
Hypoxia-Preconditioned Human Umbilical Vein Endothelial Cells Protect Against Neurovascular Damage After Hypoxic Ischemia in Neonatal Brain

Yi-Chao Lee, Ying-Chao Chang, Chia-Ching Wu,Chao-Ching Huang

Molecular Neurobiology (Springer) Taiwan, 19 February 2018

Neuroscience

Key words: Neonatal brain injury, neurovascular protection, hypoxia-preconditioned, human umbilical vein endothelial cells, hypoxia-inducible factor 1-alpha

Organism: Human

Cell Line: HUVECs (Human umbilical vein endothelial cells)

458
Inflammatory Monocytes Drive Influenza A Virus–Mediated Lung Injury in Juvenile Mice

Bria M. Coates, Kelly L. Staricha, Clarissa M. Koch, Yuan Cheng, Dale K. Shumaker, G. R. Scott Budinger, Harris Perlman, Alexander V. Misharin and Karen M. Ridge

Journal of Immunology (American Association of Immunologists) USA, 14 February 2018

Immunology

Key words: Influenza A virus (IAV), NLRP3 inflammasome, cytokines, monocytes

Organism: Mouse

Tissue: Lung, Heart

459
Preclinical In Vitro and In Vivo Evaluation of [18F]FE@SUPPY for Cancer PET Imaging: Limitations of a Xenograft Model for Colorectal Cancer

T. Balber, J.Singer, N. Berroterán-Infante, M. Dumanic, L. Fetty, J. Fazekas-Singer , C. Vraka, L. Nics, M. Bergmann, K. Pallitsch, H. Spreitzer, W. Wadsak , M. Hacker, E. Jensen-Jarolim, H. Viernstein, and M. Mitterhauser ,

Contrast Media and Molecular Imaging (Wiley) Austria, 13 February 2018

Oncology

Key words: [18F]FE@SUPPY, Cancer PET Imaging, Colorectal Cancer

Organism: Mouse

Tissue: Colon

Pathological State: Cancer

460
Calcium signaling mediates five types of cell morphological changes to form neural rosettes

Hana Hříbková, Marta Grabiec, Dobromila Klemová, Iva Slaninová, Yuh-Man Sun

Journal of Cell Science (The Company of Biologists) Czech Republic, 12 February 2018

Neuroscience

Key words: Embryonic stem cells, neural stem cell niche, neural rosette formation, calcium, neurogenesis, adherens junctions, cytoskeleton proteins

Organism: Human

Cell Line: Human ESC-derived neural rosettes

461
Functional loss of p53 cooperates with the in vivo microenvironment to promote malignant progression of gastric cancers

Junko Ohtsuka, Hiroko Oshima, Issei Ezawa, Ryo Abe, Masanobu Oshima and Rieko Ohki

Scientific Reports (Nature) Japan, 02 February 2018

Oncology

Key words: Gastric cancer, p53 mutations, tumour-suppressor proteins

Organism: Mouse

Tissue: Stomach

Pathological State: Cancer

462
Angiogenin Attenuates Scar Formation in Burn Patients by Reducing Fibroblast Proliferation and Transforming Growth Factor β1 Secretion

SC Pan, CH Lee, CL Chen, WY Fang, LW Wu

Annals of Plastic Surgery (LWW Journals) Taiwan, 01 February 2018

Regenerative Medicine

Key words: angiogenin, fibroblast, scar, Smad2, transforming growth factor β1

Organism: Human

Tissue: Skin

Pathological State: Burn Wound

463
Differentiation-associated urothelial cytochrome P450 oxidoreductase predicates the xenobiotic-metabolizing activity of “luminal” muscle-invasive bladder cancers

Simon C. Baker, Volker M. Arlt, Radek Indra, Madeleine Joel, Marie Stiborová, Ian Eardley, Niaz Ahmad, Wolfgang Otto, Maximilian Burger, Peter Rubenwolf, David H. Phillips, Jennifer Southgate

Molecular Carcinogenesis (Wiley) UK, 01 February 2018

Oncology

Key words: Urothelium, carcinogens, normal human urothelial (NHU) cells , EROD activity

Organism: Human

Cell Line: NHU cells (Normal human urothelial)

464
Grey matter OPCs are less mature and less sensitive to IFNγ than white matter OPCs: consequences for remyelination

Dennis H. Lentferink, Jacomien M. Jongsma, Inge Werkman and Wia Baron

Scientific Reports (Nature) The Netherlands, 01 February 2018

Neuroscience

Key words: Multiple sclerosis (MS), central nervous system, oligodendrocyte progenitor cells (OPCs)

Organism: Rat

Cell Line: OPS cells (Oligodendrocyte progenitor cells)

465
Assessing the selective therapeutic efficacy of superparamagnetic erlotinib nanoparticles in lung cancer by using quantitative magnetic resonance imaging and a nuclear factor kappa-B reporter gene system

Fei-Ting Hsu, Hua-Shan Liu, Ahmed Atef Ahmed Ali, Ping-Huei Tsai, Yu-Chieh Kao, Chia-Feng Lu, Hsu-Shan Huang Cheng-Yu Chen

Nanomedicine: Nanotechnology, Biology and Medicine (Elsevier) Taiwan, 31 January 2018

Nanomedicine

Key words: Erlotinib, superparamagnetic iron oxide, magnetic resonance imaging, nuclear factor-κBNon-small-cell lung cancer

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

466
Expression of cystatin C in the female reproductive tract and its effect on human sperm capacitation

Robert Kuo-Kuang Lee, Huan-Chin Tseng, Yuh-Ming Hwu, Chi-Chen Fan, Ming-Huei Lin, Jhih-Jie Yu, Ling-Yu Yeh and Sheng-Hsiang Li

Reproductive Biology and Endocrinology (Springer) Taiwan, 30 January 2018

Reproductive Medicine

Key words: Cystatin C (CST3), seminal plasma, sperm protein tyrosine phosphorylation

Organism: Human

Tissue: Uterus

467
AXL promotes Zika virus infection in astrocytes by antagonizing type I interferon signalling

Jian Chen, Yi-feng Yang, Yu Yang, Peng Zou, Jun Chen, Yongquan He, Sai-lan Shui, Yan-ru Cui, Ru Bai, Ya-jun Liang, Yunwen Hu, Biao Jiang, Lu Lu, Xiaoyan Zhang, Jia Liu and Jianqing Xu

Nature Microbiology (Nature) China, 29 January 2018

Microbiology

Key words: Zika virus (ZIKV), neonatal microcephaly, Guillain–Barré syndrome, AXL

Organism: Mosquito

Pathological State: Virus Infection

Cell Line: C6/36 cells

468
SPK1-transfected UCMSC has better therapeutic activity than UCMSC in the treatment of experimental autoimmune encephalomyelitis model of Multiple sclerosis

Yun-Liang Wang, Peng Xue, Chun-Yang Xu, Zhen Wang, Xin-Shan Liu, Lin-Lin Hua, Hong-Ying Bai, Zhi-Lei Zeng, Hai-Feng Duan and Jin-Feng Li

Scientific Reports (Nature) China, 29 January 2018

Neuroscience

Key words: Multiple Sclerosis (MS), central nervous system , permanent neurological damage, cytokine

Organism: Human

Cell Line: Human umbilical cord mesenchymal stem cells (HUC-MSC-SPK1)

469
Histamine drives severity of innate inflammation via histamine 4 receptor in murine experimental colitis

J B Wechsler, A Szabo, C L Hsu, R A Krier-Burris, H A Schroeder, M Y Wang, R G Carter, T E Velez, L M Aguiniga, J B Brown, M L Miller, B K Wershil, T A Barrett and P J Bryce

Mucosal Immunology (Nature) USA, 24 January 2018

Immunology

Organism: Mouse

Tissue: Colon

Pathological State: Colitis

470
Injectable hydroxyphenyl derivative of hyaluronic acid hydrogel modified with RGD as scaffold for spinal cord injury repair

Kristyna Zaviskova, Dmitry Tukmachev, Jana Dubisova, Irena Vackova, Ales Hejcl, Julie Bystronova, Martin Pravda, Ivana Scigalkova, Romana Sulakova, Vladimir Velebny, Lucie Wolfova, Sarka Kubinova

Journal of Biomedical Materials Research (Wiley) Czech Republic, 23 January 2018

Regenerative Medicine

Key words: Hydrogel, spinal cord injury (SCI), hydroxyphenyl derivative of hyaluronic acid (HA-PH)

Organism: Rat

Tissue: Spinal Cord

Pathological State: Spinal Cord Injury

471
CCR5/CCL5 axis interaction promotes migratory and invasiveness of pancreatic cancer cells

Santosh Kumar Singh, Manoj K. Mishra, Isam-Eldin A. Eltoum, Sejong Bae, James W. Lillard Jr. and Rajesh Singh

Scientific Reports (Nature) USA, 22 January 2018

Oncology

Key words: Pancreatic cancer (PC), CCR5, CCL5, F-actin polymerization

Organism: Human

Tissue: Pancreas

Pathological State: Cancer

472
Posterior reversible encephalopathy syndrome in stroke-prone spontaneously hypertensive rats on high-salt diet

Fanny Herisson, Iris Zhou, Jerome Mawet, E Du, Arnavaz H Barfejani, Tao Qin, Marilyn J Cipolla, Philip Z Sun, Natalia S Rost, Cenk Ayata

Journal of Cerebral Blood Flow and Metabolism (SAGE Journals) USA, 19 January 2018

Oncology

Key words: Animal models, hypertension, posterior cerebral reversible encephalopathy, cerebral blood flow, white matter

Organism: Rat

Tissue: Brain

Pathological State: Encephalopathy

473
Simvastatin induces G1 arrest by up-regulating GSK3β and down-regulating CDK4/cyclin D1 and CDK2/cyclin E1 in human primary colorectal cancer cells

Ming-Jenn Chen, An-Ching Cheng, Ming-Fen Lee, Yi-Chiang Hsu

Journal of Cellular Physiology (Wiley) Taiwan, 15 January 2018

Oncology

Key words: Simvastatin (SIM), colorectal cancer (CRC), CDK4/cyclin D1

Organism: Human

Tissue: Colon

Pathological State: Cancer

474
Canine macrophages can like human macrophages be in vitro activated toward the M2a subtype relevant in allergy

Ina Herrmanna, Jelena Gotovina, Judit Fazekas-Singera, Michael B.Fischer, Karin Hufnagl, Rodolfo Bianchini, Erika Jensen-Jarolima

Developmental and Comparative Immunology (Elsevier) Austria, 10 January 2018

Immunology

Key words: Allergy , canine, comparative, DH82M1 macrophage, M2a macrophage, polarization

Organism: Dog, Human

Pathological State: Cancer

Cell Line: U937 and DH82 cells (Makrophage like cells)

475
Formation of nanotubular TiO2 structures with varied surface characteristics for biomaterial applications

Robinson Aguirre, Mónica Echeverry-Rendón, David Quintero, Juan G. Castaño, Martin C. Harmsen, Sara Robledo, Félix Echeverría E

Journal of Biomedical Materials Research (Wiley) Colombia, 09 January 2018

Biological Materials

Key words: Anodization, titanium, nanotubular TiO2, counterion

Organism: Human

Cell Line: Adipose tissue derived stromal cells (ADSC)

476
Physical-chemical characterization and biological assessment of simple and lithium-doped biological-derived hydroxyapatite thin films for a new generation of metallic implants

A.C.Popescu, P.E.Florian, G.E.Stan, G.Popescu-Pelin, I.Zgura, M.Enculescu, F.N.Oktard, R.Trusca, L.E.Sima, A.Roseanu, L.Duta

Applied Surface Science (Elsevier) Romania, Turkey, 06 January 2018

Regenerative Medicine

Key words: Biological-derived hydroxyapatite, Lithium doping, Pulsed Laser Deposition, Sustainable resources, In vitro assessment

Organism: Human

Cell Line: Human mesenchymal stem cells (hMSCs)

477
Does combined therapy of curcumin and epigallocatechin gallate have a synergistic neuroprotective effect against spinal cord injury?

Jiri Ruzicka, Lucia Machova Urdzikova, Barbora Svobodova, Anubhav G. Amin, Kristyna Karova, Jana Dubisova, Kristyna Zaviskova, Sarka Kubinova, Meic Schmidt, Meena Jhanwar-Uniyal, and Pavla Jendelova

Neural Regeneration Research (Publishing House of Neural Regeneration Research) Czech Republic, USA, 01 January 2018

Regenerative Medicine

Key words: spinal cord injury, epigallocatechin gallate, curcumin, inflammatory response, neural regeneration

Organism: Rat

Tissue: Spinal Cord

Pathological State: Spinal Cord Injury

478
Zinc finger protein 143 expression is closely related to tumor malignancy via regulating cell motility in breast cancer

AR Paek, JY Mun, KM Hong, J Lee, DW Hong, HJ You

BMb Reports (NCBI) South Korea, 31 December 2017

Oncology

Key words: Invasive ductal carcinoma, Metastasis, Motility, ZNF143

Organism: Human

Tissue: Breast

Pathological State: Cancer

479
AKT3 drives adenoid cystic carcinoma development in salivary glands

Katalin Zboray, Julian Mohrherr, Patricia Stiedl, Klemens Pranz, Laura Wandruszka, Beatrice Grabner, Robert Eferl, Richard Moriggl, Dagmar Stoiber, Kazuhito Sakamoto, Kay-Uwe Wagner, Helmut Popper, Emilio Casanova, Herwig P. Moll

Cancer Medicine (Wiley) Austria, 28 December 2017

Oncology

Key words: AKT3, adenoid cystic carcinoma, MMTV-tTA mouse model, oncogene addiction, salivary gland cancer

Organism: Mouse

Tissue: Salivary Gland

Pathological State: Cancer

480
A benchmark for comparing precision medicine methods in thyroid cancer diagnosis using tissue microarrays

Ching-Wei Wang, Yu-Ching Lee, Evelyne Calista, Fan Zhou, Hongtu Zhu, Ryohei Suzuki, Daisuke Komura, Shumpei Ishikawa, Shih-Ping Cheng

Bioinformatics (Oxford University Press) Taiwan, USA, Japan, 23 December 2017

Biological Methods

Key words: precision medicine, cancer diagnosis, tissue microarray

Organism: Human

Tissue: Thyroid

Pathological State: Cancer

481
Actein induces autophagy and apoptosis in human bladder cancer by potentiating ROS/JNK and inhibiting AKT pathways

Lu Ji, Bing Zhong, Xi Jiang, Fei Mao, Gang Liu, Bin Song, Cheng-Yuan Wang, Yong Jiao, Jiang-Ping Wang, Zhi-Bin Xu, Xing Li, and Bo Zhan

Oncotarget (Impact Journals) China, 22 December 2017

Oncology

Key words: human bladder cancer, Actein (ACT), autophagy and apoptosis, ROS and JNK, AKT

Organism: Mouse, Human

Tissue: Xenograft Tumor, Liver, Lung, Kidney

Pathological State: Cancer

482
Recurrent infection progressively disables host protection against intestinal inflammation

WH Yang, DM Heithoff, PV Aziz, M Sperandio, V Nizet, MJ Mahan, JD Marth

Science (American Association for the Advancement of Science) USA, Germany, 22 December 2017

Immunology

Key words: Recurrent infection, host protection, intestinal inflammation

Organism: Mouse

Tissue: Small Intestine, Colon

Pathological State: Inflammation

483
CD151, A Novel Host Factor of Nuclear Export Signaling in Influenza Virus Infection

Yongkang Qiao, Yan Ya, Kai Sen Tan, Sheryl SL. Tan, Ju Ee Seet, Thiruma Valavan Arumugam, Vincent TK. Chow, De Yun Wang

Journal of Allergy and Clinical Immunology (Elsevier) Singapore, 21 December 2017

Immunology

Key words: Influenza A virus (IAV), CD151, nuclear export, host innate immunity, inflammasome, IAV severity

Organism: Mouse

Tissue: Lung

Pathological State: Virus Infection

484
Renal allograft rejection, lymphocyte infiltration, and de novo donor-specific antibodies in a novel model of non-adherence to immunosuppressive therapy

Louisa Kühne, Bettina Jung, Helen Poth, Antonia Schuster, Simone Wurm, Petra Ruemmele, Bernhard Banas, Tobias Bergler

BMC Immunology (BioMed Central) Germany, 19 December 2017

Immunology

Key words: Donor specific antibodies, humoral rejection, renal transplantation, non-adherence, leukocyte infiltration, BAFF

Organism: Rat

Tissue: Kidney

Pathological State: Organ Transplantation

485
Mitochondrial ROS activates ERK/autophagy pathway as a protected mechanism against deoxypodophyllotoxin-induced apoptosis

Sang-Hun Kim, Kwang-Youn Kim, Sul-Gi Park, Sun-Nyoung Yu, Young-Wook Kim, Hyo-Won Nam, Hyun-Hee An, Young-Woo Kim, and Soon-Cheol Ahn

Oncotarget (Impact Journals) South Korea, USA, 19 December 2017

Oncology

Key words: Deoxypodophyllotoxin, apoptosis, autophagy, mitochondrial ROS, ERK

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

486
Magnolol inhibits venous remodeling in mice

Hanna Kuk, Caroline Arnold, Ralph Meyer, Markus Hecker and Thomas Korff

Scientific Reports (Nature) Germany, 19 December 2017

Cardiology

Key words: Magnolol, venous vasculature, endothelial cells, varicose/spider veins, peripheral vascular disease

Organism: Human

Cell Line: HUVECs (Human umbilical vein endothelial cells)

487
TDP-43 proteolysis is associated with astrocyte reactivity after traumatic brain injury in rodents

CY Huang, YC Lee, PC Li, PC Liliang, K Lu, KW Wang, LC Chang, LY Shiu, MF Chen, YT Sun, HK Wang

Journal of Neuroimmunology (Elsevier) Taiwan, 15 December 2017

Neuroscience

Key words: Astrocyte, Astrogliosis, Traumatic brain injury, Transactivation response DNA-binding protein 43

Organism: Rat

Tissue: Brain

Pathological State: Traumatic Brain Injury

488
Novel Hydrogel-Advanced Modified Clay Nanocomposites as Possible Vehicles for Drug Delivery and Controlled Release

Raluca Ianchis, Claudia M. Ninciuleanu, Ioana C. Gifu, Elvira Alexandrescu, Raluca Somoghi, Augusta R. Gabor, Silviu Preda, Cristina L. Nistor, Sabina Nitu, Cristian Petcu, Madalina Icriverzi, Paula E. Florian and Anca M. Roseanu

Nanomaterials (MDPI) Romania, 13 December 2017

Nanomedicine

Key words: hydrogel; clay; nanocomposites; biocompatibility

Organism: Cow

Cell Line: HT29 and MDBK cells

489
18F-FDG PET Biomarkers Help Detect Early Metabolic Response to Irreversible Electroporation and Predict Therapeutic Outcomes in a Rat Liver Tumor Model

Xifu Wang, Zhanliang Su, Tianchu Lyu, Matteo Figini, Daniel Procissi, Junjie Shangguan, Chong Sun, Bin Wang, Na Shang, Shanzhi Gu, Quanhong Ma, Andrew C. Gordon, Kai Lin, Jian Wang, Robert J. Lewandowski, Riad Salem, Vahid Yaghmai, Andrew C. Larson, Zhuoli Zhang

Radiology (Radiological Society of North America) USA, China, 12 December 2017

Radiotherapy, Oncology

Key words: 18F-FDG PET, Biomarkers, Metabolic Response, Irreversible Electroporation, Liver Tumor

Organism: Rat

Tissue: Liver

Pathological State: Cancer

490
Comparison of MOLLI, shMOLLLI, and SASHA in discrimination between health and disease and relationship with histologically derived collagen volume fraction

Nicholas Child, Gonca Suna, Darius Dabir, May-Lin Yap, Toby Rogers, Misha Kathirgamanathan, Eduardo Arroyo-Ucar, Rocio Hinojar, Islam Mahmoud, Christopher Young, Olaf Wendler, Manuel Mayr, Banher Sandhu, Geraint Morton, Marion Muhly-Reinholz, Stefanie Dimmeler, Eike Nagel, Valentina O Puntmann

European Heart Journal (Oxford University Press) UK, Germany, Spain, 11 December 2017

Cardiology

Key words: T1 mapping, MOLLI, shMOLLI, SASHA, collagen, aortic valve stenosis, myocardium, troponin, myocardial fibrosis, collagen, respiratory care units, therapeutic equivalency, transverse spin relaxation time

Organism: Human

Tissue: Heart

Pathological State: Fibrosis

491
INO80 haploinsufficiency inhibits colon cancer tumorigenesis via replication stress-induced apoptosis

Shin-Ai Lee, Han-Sae Lee, Shin-Kyoung Hur, Sang Won Kang, Goo Taeg Oh, Daekee Lee, and Jongbum Kwon

Oncotarget (Impact Journals) South Korea, 06 December 2017

Oncology

Key words: INO80 chromatin remodeling complex, colon cancer, APC Min mouse model, replication stress, apoptosis

Organism: Mouse

Tissue: Small Intestine, Colon

Pathological State: Cancer

492
Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer

An Ning Cheng, Chi-Chen Fan, Yu-Kang Lo, Cheng-Liang Kuo, Hui-Chun Wang, I.-Hsin Lien, Shu-Yu Lin, Chung-Hsing Chen, Shih Sheng Jiang, I.-Shou Chang, Hsueh-Fen Juan, Ping-Chiang Lyu and Alan Yueh-Luen Lee

Scientific Reports (Nature) Taiwan, 05 December 2017

Oncology

Key words: Phosphorylation, cancer therapeutic resistance, Cdc7-Dbf4 kinase, stress

Organism: Human

Tissue: Mucosa

Pathological State: Cancer

493
Nocturnal resveratrol administration inhibits chemically induced breast cancer formation in rats

T. KISKOVA, V. DEMECKOVA, Z. JENDZELOVSKA, M. KIKTAVA, K. VENGLOVSKA, M. BOHMDORFER, W. JAGER, T. THALHAMMER

JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (Polish Physiological Society) Slovakia, Austria, 01 December 2017

Oncology

Key words: resveratrol, circadian rhythm, carcinogenesis, breast cancer, immunity, reactive oxygen species

Organism: Rat

Tissue: Breast

Pathological State: Cancer

494
IgE autoreactivity in bullous pemphigoid: eosinophils and mast cells as major targets of pathogenic immune reactants

P.C. Freire, C.H. Muñoz, G. Stingl

British Journal of Dermatology (Wiley) Austria, 28 November 2017

Dermatology

Key words: Bullous pemphigoid (BP), urticarial eruptions, IgG, IgE

Organism: Human

Tissue: Skin

Pathological State: Bullous Pemphigoid

495
Interaction of factor VII activating protease (FSAP) with neutrophil extracellular traps (NETs)

Simona Grasso, Ariane Neumann, Irene M.Lang, Michael Etscheid, Marenvon Köckritz-Blickwede, Sandip M.Kanse

Thrombosis Research (Elsevier) Austria, Germany, Norway, 21 November 2017

Cell Biology

Key words: NETs, FSAP, thrombosis, inflammation

Organism: Human

Tissue: Blood Vessels

496
Analysis of anti-TNF-induced skin lesions reveals strong Th1 activation with some distinct immunological characteristics

E. Stoffel, H. Maier, E. Riedl, M.-C. Brüggen, B. Reininger, M. Schaschinger, C. Bangert, E. Guenova, G. Stingl, P.M. Brunner

British Journal of Dermatology (Wiley) Austria, USA, 16 November 2017

Dermatology

Key words: Psoriasiform, eczematous eruptions, anti-TNF-α therapy, IFN-γ

Organism: Human

Tissue: Skin

Pathological State: Crohn's Disease, Colitis, Rheumatoid Arthritis, Psoriasis, Eczema

497
Chronic Stress Alters Striosome-Circuit Dynamics, Leading to Aberrant Decision-Making

Alexander Friedman, Daigo Homma, Bernard Bloem, Leif G.Gibb, Ken-ichi Amemori, Dan Hu, Sebastien Delcasso, Timothy F.Truong, Joyce Yang, Adam S.Hood, Katrina A.Mikofalvy, Dirk W.Beck, Norah Nguyen, Erik D.Nelson, Sebastian E.Toro Arana, Ruth H.Vorder Bruegge, Ki A.Goosens, Ann M.Graybiel

CELL (Cell Press) USA, 16 November 2017

Neuroscience

Key words: Striatum, basal ganglia, cost-benefit, prefrontal cortex, optogenetics, prelimbic cortex, parvalbumin-positive interneurons, fast-spiking interneuron, sexcitation-inhibition balance

Organism: Rat

Tissue: Brain

498
Phospholipase D inhibitors reduce human prostate cancer cell proliferation and colony formation

Amanda R Noble, Norman J Maitland, Daniel M Berney and Martin G Rumsby

British Journal of Cancer (Nature) UK, 14 November 2017

Oncology

Key words: Phospholipases, mTOR, PKB/Akt, prostate cancer (PCa), benign prostatic hyperplasia (BPH)

Organism: Human

Tissue: Kidney, Prostate

Pathological State: Cancer

499
Controlled release of liposome-encapsulated temozolomide for brain tumour treatment by convection-enhanced delivery

Chung-Yin Lin, Rui-Jin Li, Chiung-Yin Huang, Kuo-Chen Wei

Journal of Drug Targeting (Taylor and Francis) Taiwan, 14 November 2017

Oncology

Key words: Convention-enhanced delivery, drug delivery, liposome, temozolomide, brain tumour

Organism: Mouse

Tissue: Brain

Pathological State: Cancer

500
Analysis of the Human Mucosal Response to Cholera Reveals Sustained Activation of Innate Immune Signaling Pathways

Daniel L. Bourque, Taufiqur Rahman Bhuiyan, Diane P. Genereux, Rasheduzzaman Rashu, Crystal N. Ellis, Fahima Chowdhury, Ashraful I. Khan, Nur Haq Alam, Anik Paul Lazina Hossain, Leslie M. Mayo-Smith, Richelle C. Charles, Ana A. Weil, Regina C. LaRocque, Stephen B. Calderwood, Edward T. Ryan, Elinor K. Karlsson, Firdausi Qadri and Jason B. Harris

Infection and Immunity (American Society for Microbiology) USA, 13 November 2017

Immunology

Key words: Vibrio cholerae infection, cholera, Caco-2 or THP-1 cells

Organism: Human

Tissue: Small Intestine

Pathological State: Bacterial Infection

501
Digital image analysis in breast pathology—from image processing techniques to artificial intelligence

Stephanie Robertson, Hossein Azizpour, Kevin Smith, Johan Hartman

Translational Research (Elsevier) Sweden, 07 November 2017

Oncology

Key words: Breast cancer, histopathology, biomarker, artificial intelligence (AI)

Organism: Human

Tissue: Breast

Pathological State: Cancer

502
Cyclin D1 promoter -56 and -54 bp CpG un-methylation predicts invasive progression in arsenic-induced Bowen’s disease

Wei-Ting Liao, Huey-Ling You, Chee-Yin Chai, Chih-Hung Lee, Cheng-Che E. Lang, Shun-Jen Chang, Chu-Ling Yui, Hsin-Su Yu

Journal of Dermatological Science (Elsevier) Taiwan, 31 October 2017

Oncology

Key words: Arsenic-induced Bowen’s disease, cyclin D1 un-methylation, aneuploidy, predictor, invasive progression

Organism: Human

Tissue: Skin

Pathological State: Bowen’s Disease, Cancer

503
HER2 challenge contest: a detailed assessment of automated HER2 scoring algorithms in whole slide images of breast cancer tissues

Talha Qaiser ,Abhik Mukherjee, Chaitanya Reddy PB, Sai D Munugoti, Vamsi Tallam, Tomi Pitkäaho, Taina Lehtimäki, Thomas Naughton, Matt Berseth, Aníbal Pedraza, Ramakrishnan Mukundan, Matthew Smith, Abhir Bhalerao, Erik Rodner, Marcel Simon, Joachim Denzler, Chao-Hui Huang, Gloria Bueno, David Snead, Ian O Ellis, Mohammad Ilyas, Nasir Rajpoot

Histopathology (Wiley) UK, 27 October 2017

Medical Image Analysis

Key words: Human epidermal growth factor receptor 2 (HER2), IHC, invasive breast cancer (BCa)

504
CCR7 Is Important for Mesangial Cell Physiology and Repair

Simone Wurm, Andreas Steege, Eva-Maria Rom-Jurek, Claudia R. van Roeyen, Armin Kurtz, Bernhard Banas, Miriam C. Banas

Journal of Histochemistry and Cytochemistry (SAGE Journals) Germany, 27 October 2017

Oncology

Key words: Homeostatic chemokine receptor CCR7, human mesangial cells, glomerulogenesis, mesangial biology

Organism: Mouse

Tissue: Kidney

505
Guanylate-binding protein 2 regulates Drp1-mediated mitochondrial fission to suppress breast cancer cell invasion

Juan Zhang, Yu Zhang, Wenshuang Wu, Fang Wang, Xinyu Liu, Guanghou Shui and Chunlai Nie

Cell Death & Disease (Nature) China, 26 October 2017

Oncology

Key words: Guanylate-binding protein 2 (GBP2), interferon-γ (IFN-γ), mitochondrial fission, shRNA

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

506
The Pericytic Phenotype of Adipose Tissue-derived Stromal Cells is Promoted by NOTCH2

Vincenzo Terlizzi, Matthias Kolibabka, Janette Kay Burgess, Hans Peter Hammes, Martin Conrad Harmsen

Stem Cells (Wiley) Germany, The Netherlands, 25 October 2017

Stem Cell Research

Key words: Diabetic retinopathy (DR), adipose tissue‐derived stromal cells (ASC), NOTCH2, human umbilical cord vein endothelial cells (HUVEC)

Organism: Human

Cell Line: HUVECs (Human umbilical vein endothelial cells)

507
The natural compound 2,3,5,4′-tetrahydroxystilbene-2-O-β-d glucoside protects against adriamycin-induced nephropathy through activating the Nrf2-Keap1 antioxidant pathway

En-Yuan Lin, Uyanga Bayarsengee, Ching-Chiung Wang, Yung-Hsiao Chiang, Chao-Wen Cheng

Environmental Toxicology (Wiley) Taiwan, 24 October 2017

Toxicology

Key words: Tetrahydroxystilbene-2-O-β-d-glucoside (THSG), Polygoni Multiflori, adriamycin (AD), quinone oxidoreductase (NQO)-1

Organism: Mouse

Tissue: Kidney

508
Initial graft size and not the innate immune response limit survival of engrafted neural stem cells

Stefanie Vogel, Markus Aswendt, Melanie Nelles, Nadine Henn, Gabriele Schneider, Mathias Hoehn

Journal of Tissue Engineering and Regenerative Medicine (Wiley) Germany, 22 October 2017

Neuroscience

Key words: Transplantation of neural stem cells (NSCs), Luc2 and copGFP, bioluminescence imaging (BLI)

Organism: Mouse

Tissue: Brain

509
Tumor angiogenesis and bone metastasis - Correlation in invasive breast carcinoma

Chong Sun, Jianmin Li, Bin Wang, Junjie Shangguan, Matteo Figini, Na Shang, Liang Pan, Zhuoli Zhang

Journal of Immunological Methods (Elsevier) USA, 21 October 2017

Oncology

Key words: Breast carcinoma, bone metastasis,tumor angiogenesis, pathological biomarkers

Organism: Human

Tissue: Breast

Pathological State: Cancer

510
TDP-43 proteolysis is associated with astrocyte reactivity after traumatic brain injury in rodents

Chih-Yuan Huang, Yi-Che Lee, Ping-Chia Li, Po-Chou Liliang, Kang Lu, Kuo-Wei Wang, Li-Ching Chang, Li-Yen Shiu, Ming-Feng Chen, Yuan-Ting Sun, Hao-kuang Wang

Journal of Neuroimmunology (Elsevier) Taiwan, 20 October 2017

Neuroscience

Key words: Astrocyte, astrogliosis, traumatic brain injury, transactivation response DNA-binding protein 43

Organism: Rat

Tissue: Brain

Pathological State: Traumatic Brain Injury

511
The non-canonical ubiquitin activating enzyme UBA6 suppresses epithelial-mesenchymal transition of mammary epithelial cells

X Liu, L Sun, DB Gursel, C Cheng, S Huang, AW Rademaker, SA Khan, J Yin, H Kiyokawa

Oncotarget (Impact Journals) USA, 20 October 2017

Oncology

Key words: ubiquitination, breast cancer, EMT, Rho GTPase, cell cycle

Organism: Human

Cell Line: MCF-10A cells

512
Human alternative Klotho mRNA is a nonsense-mediated mRNA decay target inefficiently spliced in renal disease

Rik Mencke, Geert Harms, Jill Moser, Matijs van Meurs, Arjan Diepstra, Henri G. Leuvenink, and Jan-Luuk Hillebrands

Journal of Clinical Investigation (American Society for Clinical Investigation) The Netherlands, 19 October 2017

Nephrology

Key words: Aging, Nephrology, Chronic kidney disease, RNA processing

Organism: Human

Cell Line: HK-2 cells

513
DNA-binding of the Tet-transactivator curtails antigen-induced lymphocyte activation in mice

Eleonora Ottina, Victor Peperzak, Katia Schoeler, Emma Carrington, Roswitha Sgonc, Marc Pellegrini, Simon Preston, Marco J. Herold, Andreas Strasser and Andreas Villunger

Nature Communications (Nature) Austria, Australia, 18 October 2017

Immunology

Key words: Tet-On/Off system, BCL2 overexpression, CRISPR/Cas9, RNA interference (RNAi)

Organism: Mouse

Tissue: Spleen

514
Cordycepin promotes apoptosis in renal carcinoma cells by activating the MKK7-JNK signaling pathway through inhibition of c-FLIPL expression

In-Hu Hwang , Seung Yoon Oh , Hyun-Jin Jang, Eunbi Jo, Jong Cheon Joo, Kyung-Bok Lee, Hwa-Seung Yoo, Mi Young Lee, Soo Jung Park, Ik-Soon Jang

PLoS One (PLOS) South Korea, 18 October 2017

Oncology

Key words: Cellular FLICE inhibitory protein (c-FLIP), NF-κB, apoptosis, cordycepin

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

515
Lactobacillus gasseri attenuates allergic airway inflammation through PPARγ activation in dendritic cells

Miao-Hsi Hsieh, Ren-Long Jan, Lawrence Shih-Hsin Wu, Pei-Chi Chen, Hui-Fang Kao,Wen-Shuo Kuo, Jiu-Yao Wang

Journal of Molecular Medicine (Springer) Taiwan, 14 October 2017

Allergy Research

Key words: Allergy asthma, lactic acid bacillus, peroxisome proliferator-activated receptor gamma (PPARγ), dendritic cells

Organism: Mouse

Tissue: Lung

Pathological State: Bacterial Infection

516
GD1a Overcomes Inhibition of Myelination by Fibronectin via Activation of Protein Kinase A: Implications for Multiple Sclerosis

Jing Qin, Arend H. Sikkema, Kristine van der Bij, Jenny C. de Jonge, Karin Klappe, Vera Nies, Johan W. Jonker, Jan Willem Kok, Dick Hoekstra and Wia Baron

Journal of Neuroscience (SFN) The Netherlands, 11 October 2017

Neuroscience

Key words: Fibronectin, ganglioside, multiple sclerosis, oligodendrocyte, remyelination

Organism: Mouse

Tissue: Brain

517
Actein induces apoptosis in leukemia cells through suppressing RhoA/ROCK1 signaling pathway

Wen-Di Zhou, Xiang Wang, Xing-Zhen Sun, Jian Hu, Rong-Rong Zhang, Ze Hong

International Journal of Oncology (Spandidos Publications) China, 10 October 2017

Oncology

Key words: Actein, apoptosis,leukemia, RhoA/ROCK1 signaling pathway

Organism: Mouse

Pathological State: Cancer

518
Therapeutic Effects of Monoclonal Antibody against Dengue Virus NS1 in a STAT1 Knockout Mouse Model of Dengue Infection

Shu-Wen Wan, Pei-Wei Chen, Chin-Yu Chen, Yen-Chung Lai, Ya-Ting Chu, Chia-Yi Hung, Han Lee, Hsuan Franziska Wu, Yung-Chun Chuang, Jessica Lin, Chih-Peng Chang, Shuying Wang, Ching-Chuan Liu, Tzong-Shiann Ho, Chiou-Feng Lin, Chien-Kuo Lee, Betty A. Wu-Hsieh, Robert Anderson, Trai-Ming Yeh and Yee-Shin Lin

The Journal of Immunology (American Association of Immunologists) Taiwan, 10 October 2017

Immunology

Key words: Dengue virus (DENV), dengue fever, DENV nonstructural protein 1 (NS1)

Organism: Mouse

Tissue: Skin

Pathological State: Virus Infection

519
Linarin sensitizes tumor necrosis factor-related apoptosis (TRAIL)-induced ligand-triggered apoptosis in human glioma cells and in xenograft nude mice

Zan-feng Xu, Xiao-ke Sun, Ying Lan, Chao Han, Yong-dong Zhang, Gang Chen

Biomedicine and Pharmacotherapy (Elsevier) China, 06 October 2017

Oncology

Key words: TRAIL, glioma, linarin (LIN), apoptosis, ROS generation

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

520
PD-1 Expression in Head and Neck Squamous Cell Carcinomas Derives Primarily from Functionally Anergic CD4+ TILs in the Presence of PD-L1+ TAMs

Austin K. Mattox, Jina Lee, William H. Westra, Robert H. Pierce, Ronald Ghossein, William C. Faquin, Thomas J. Diefenbach, Luc G. Morris, Derrick T. Lin, Lori J. Wirth, Armida Lefranc-Torres, Eiichi Ishida, Patrick D. Chakravarty, Lauren Johnson, Yang C. Zeng, Huabiao Chen, Mark C. Poznansky, Neil M. Iyengar and Sara I. Pai

Cancer Research (AACR Publications) USA, 25 September 2017

Oncology

Key words: Oral tongue squamous cell carcinoma (OTSCC), PD-1, tumor microenvironment (TME), tumor-infiltrating lymphocytes (TIL)

Organism: Human

Tissue: Head and Neck

Pathological State: Cancer

521
Axonal components of nerves innervating the human arm

Bernhard Gesslbauer, Laura A. Hruby, Aidan D. Roche, Dario Farina, Roland Blumer, Oskar C. Aszmann

Annals of Neurology (Wiley) Austria, 20 September 2017

Neuroscience

Key words: Nerves, sensory and motir axons, spinal cord, neurofilament

Organism: Human

Tissue: Nerves

522
The microRNA ame-miR-279a regulates sucrose responsiveness of forager honey bees (Apis mellifera)

Fang Liu, Tengfei Shi, Wei Yin, Xin Su, Lei Qi, Zachary Y.Huang, Shaowu Zhang, Linsheng Yu

Insect Biochemistry and Molecular Biology (Elsevier) USA, China, 20 September 2017

Zoology

Key words: microRNA, honey bee, proboscis extension reflex, sucrose responsiveness, division of labour

Organism: Honey Bee

Tissue: Brain

523
Role of BDNF and neurotrophic receptors in human inner ear development

LJ Chacko, MJF Blumer, E Pechrigg, H Rask-Andersen, W Dietl, A Haim, H Fritsch, R Glueckert, J Dudas, A Schrott-Fischer

Cell and Tissue Research (Springer) Austria, Seweden, 19 September 2017

Developmental Biology

Key words: Inner ear, Human, BDNF, Neurotrophin receptors, In situ hybridization

Organism: Human

Tissue: Bone

524
Tumor-associated B-cells induce tumor heterogeneity and therapy resistance

Rajasekharan Somasundaram, Gao Zhang, Mizuho Fukunaga-Kalabis, Michela Perego, Clemens Krepler, Xiaowei Xu, Christine Wagner, Denitsa Hristova, Jie Zhang, Tian Tian, Zhi Wei, Qin Liu, Kanika Garg, Johannes Griss, Rufus Hards, Margarita Maurer, Christine Hafner, Marius Mayerhöfer, Georgios Karanikas, Ahmad Jalili, Verena Bauer-Pohl, Felix Weihsengruber, Klemens Rappersberger, Josef Koller, Roland Lang, Courtney Hudgens, Guo Chen, Michael Tetzlaff, Lawrence Wu, Dennie Tompers Frederick, Richard A. Scolyer, Georgina V. Long, Manashree Damle, Courtney Ellingsworth, Leon Grinman, Harry Choi, Brian J. Gavin, Margaret Dunagin, Arjun Raj, Nathalie Scholler, Laura Gross, Marilda Beqiri, Keiryn Bennet

Nature Communications (Nature) USA, Austria, 19 September 2017

Oncology

Key words: Melanoma, oncogenic BRAFV600E, growth factor FGF-2,

Organism: Human

Tissue: Skin, Lymphoid Tissue

Pathological State: Cancer

525
Development of a radiolabeled caninized anti-EGFR antibody for comparative oncology trials

Judit Fazekas-Singer, Neydher Berroterán-Infante, Christina Rami-Mark, Monika Dumanic, Miroslawa Matz, Michael Willmann, Fritz Andreae, Josef Singer, Wolfgang Wadsak, Markus Mitterhauser, and Erika Jensen-Jarolim

Oncotarget (Impact Journals) Austria, 15 September 2017

Oncology

Key words: epidermal growth factor receptor, radio-immunotherapy, canine mammary carcinoma, canine antibody, comparative oncology

Organism: Dog

Tissue: Breast

Pathological State: Cancer

526
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) promotes EGF receptor signaling of oral squamous cell carcinoma metastasis via the complex N-glycosylation

W-F Chiang, T-M Cheng, C-C Chang, S-H Pan, C A Changou, T-H Chang, K-H Lee, S-Y Wu, Y-F Chen, K-H Chuang, D-B Shieh, Y-L Chen, C-C Tu, W-L Tsui and M-H Wu

Oncogene (Nature) Taiwan, 11 September 2017

Oncology

Key words: Glycosylation, CEACAM6, OSCC (oral squamous cell carcinoma), EGFR

Organism: Human

Pathological State: Cancer

Cell Line: OC-2 and OEC-M1 cells

527
The Novel Compound Sul-121 Preserves Endothelial Function and Inhibits Progression of Kidney Damage in Type 2 Diabetes Mellitus in Mice

S. P. H. Lambooy, A. Bidadkosh, D. Nakladal, A. van Buiten, R. A. T. Girgis, A. C. van der Graaf, T. J. Wiedenmann, R. A. Koster, P. Vogelaar, H. Buikema, R. H. Henning and L. E. Deelman

Scientific Reports (Nature) The Netherlands, 11 September 2017

Nephrology

Key words: Type 2 diabetes mellitus (T2DM), diabetic nephropathy, Sul-121, glomerular fibronectin expression

Organism: Mouse

Tissue: Kidney

Pathological State: Diabetes

528
A green tea polyphenol epigallocatechin-3-gallate enhances neuroregeneration after spinal cord injury by altering levels of inflammatory cytokines

Lucia Machova Urdzikova, Jiri Ruzicka, Kristyna Karova, Anna Kloudova, Barbora Svobodova, Anubhav Amin, Jana Dubisova, Meic Schmidt, Sarka Kubinova, Meena Jhanwar-Uniyal, Pavla Jendelova

Neuropharmacology (Elsevier) Czech Republic, 09 September 2017

Neuroscience

Key words: EGCG, green tea, spinal cord injury, neuroregeneration, cytokines, neuroprotection, p65NFkB

Organism: Rat

Tissue: Spinal Cord

Pathological State: Spinal Cord Injury

529
579 High-risk human papillomavirus infection in Bowen’s disease and Squamous Cell Carcinomas of the hands

S.Dorfe, S.Haas, P.Birner, R.Kirnbauer, P.Petzelbauer, S.Radakovic, H.Pehamberger, L.Harpain, A.Handisurya

Journal of Investigative Dermatology (Elsevier) Austria, 08 September 2017

Dermatology

Key words: Papillomavirus infection, Bowen’s disease, squamous cell carcinomas

Organism: Human

Tissue: Skin

Pathological State: Bowen’s Disease, Cancer

530
Exploring Metabolic Configurations of Single Cells within Complex Tissue Microenvironments

Anne Miller, Csörsz Nagy, Bernhard Knapp, Johannes Laengle, Elisabeth Ponweiser, Marion Groeger, Philipp Starkl, Michael Bergmann, Oswald Wagner, Arvand Haschemi

Cell Metabolism (Elsevier) Austria, 07 September 2017

Cell Biology

Key words: Metabolic configuration, single cell, intracellular metabolism, intercellular metabolism, enzyme histochemistry, microenvironment, immunometabolism, cancer metabolism, metabolic biomarke, metabolic imaging method

Organism: Mouse, Human

Tissue: Liver, Muscle, Colon, Breast

Pathological State: Cancer

531
4103Validation of cardiac magnetic resonance T1 mapping in cardiac amyloidosis

F. Duca, C. Zotter-Tufaro, A.A. Kammerlander, A. Panzenboeck, S. Aschauer, B. Boerries, H. Agis, R. Kain, D. Bonderman, J. Mascherbauer

European Heart Journal (Oxford University Press) Austria, 29 August 2017

Cardiology

Key words: cardiac amyloidosis, cardiac mri

Organism: Human

Tissue: Heart

Pathological State: Cardiac Amyloidosis

532
Placental Dysfunction Underlies Increased Risk of Fetal Growth Restriction and Stillbirth in Advanced Maternal Age Women

Samantha C. Lean, Alexander E. P. Heazell, Mark R. Dilworth, Tracey A. Mills and Rebecca L. Jones

Scientific Reports (Nature) UK, 29 August 2017

Reproductive Medicine

Key words: Ageing, disease model, intrauterine growth, reproductive disorders

Organism: Human

Tissue: Placenta

533
Selective targeting of a novel vasodilator to the uterine vasculature to treat impaired uteroplacental perfusion in pregnancy

Natalie Cureton, Iana Korotkova, Bernadette Baker, Susan Greenwood, Mark Wareing, Venkata R Kotamraju, Tambet Teesalu, Francesco Cellesi, Nicola Tirelli, Erkki Ruoslahti, John D Aplin, and Lynda K Harris

Theranostics (NCBI) UK, USA, Estonia, Italy, 29 August 2017

Reproductive Medicine

Key words: pregnancy, placenta, nitric oxide, endothelium, vascular biology, drug targeting

Organism: Mouse

Tissue: Placenta

534
Loss of host-derived osteopontin creates a glioblastoma-promoting microenvironment

Frank Szulzewsky, Nina Schwendinger, Dilansu Güneykaya, Patrick J Cimino, Dolores Hambardzumyan, Michael Synowitz, Eric C Holland, Helmut Kettenmann

Neuro-Oncology (Oxford University Press) USA, Germany, 26 August 2017

Oncology

Key words: glioblastoma, microglia, macrophage, osteopontin, SPP1, glioblastoma cd45 antigens macrophage-1 antigen macrophages microglia monocytes brain mice neoplasms osteopontin

Organism: Human

Pathological State: Cancer

Cell Line: Ki67 cells

535
Combination of cuprizone and experimental autoimmune encephalomyelitis to study inflammatory brain lesion formation and progression

Bernhard Josef Rüther,Miriam Scheld,Daniela Dreymueller,Tim Clarner,Eugenia Kress,Lars-Ove Brandenburg,Tine Swartenbroekx,Chloé Hoornaert,Peter Ponsaerts,Petra Fallier-Becker,Cordian Beyer,Sven Olaf Rohr,Christoph Schmitz,Uta Chrzanowski,Tanja Hochstrasser,Stella Nyamoya,Markus Kipp

GLIA (Wiley) Germany, 24 August 2017

Neuroscience

Key words: Brain-intrinsic degenerative cascades, multiple sclerosis, Cup/EAE model

Organism: Mouse

Tissue: Brain

Pathological State: Encephalomyelitis

536
Tumor-Associated Macrophages Promote Epigenetic Silencing of Gelsolin through DNA Methyltransferase 1 in Gastric Cancer Cells

Hao-Chen Wang, Chin-Wang Chen, Chia-Lung Yang, I-Min Tsai, Ya-Chin Hou, Chang-Jung Chen and Yan-Shen Shan

Cancer Immunology Research (AACR Publications) Taiwan, 23 August 2017

Oncology

Key words: Tumor suppressor gelsolin (GSN), gastric cancer, DNA methylation

Organism: Human

Tissue: Endometrium

Pathological State: Cancer

537
Zika virus infects renal proximal tubular epithelial cells with prolonged persistency and cytopathic effects

Jian Chen, Yi-feng Yang, Jun Chen, Xiaohui Zhou, Zhaoguang Dong, Tianyue Chen, Yu Yang, Peng Zou, Biao Jiang, Yunwen Hu, Lu Lu, Xiaoyan Zhang, Jia Liu, Jianqing Xu and Tongyu Zhu

Emerging Microbes and Infections (Nature) China, 23 August 2017

Immunology, Virology

Key words: Cytopathic effects, prolonged persistency, renal proximal tubular epithelial cells, urinary system, Zika virus

Organism: Mouse

Tissue: Kidney

Pathological State: Virus Infection

538
Efficient cell death induction in human glioblastoma cells by photodynamic treatment with Tetrahydroporphyrin-Tetratosylat (THPTS) and ionizing irradiation

Peter Hambsch, Yury P. Istomin, Dimitri A. Tzerkovsky, Ina Patties, Jochen Neuhaus, Rolf-Dieter Kortmann, Stanislav Schastak, and Annegret Glasow

Oncotarget (Impact Journals) Germany, Belarus, 23 August 2017

Oncology

Key words: photodynamic therapy, glioblastoma, THPTS, combination, ionizing radiation

Organism: Human

Cell Line: Human authenticated GBM cell lines (A-172, U-87 MG, and DBTRG-05MG)

539
Reactive oxygen species–mediated switching expression of MMP-3 in stromal fibroblasts and cancer cells during prostate cancer progression

Chia-Ling Hsieh, Che-Ming Liu, Hsin-An Chen, Shun-Tai Yang, Katsumi Shigemura, Koichi Kitagawa, Fukashi Yamamichi, Masato Fujisawa, Yun-Ru Liu, Wei-Hua Lee, Kuan-Chou Chen, Chia-Ning Shen, Cheng-Chieh Lin, Leland W. K. Chung and Shian-Ying Sung

Scientific Reports (Nature) Taiwan, 22 August 2017

Oncology

Key words: Stromelysin 1 (MMP-3) and 2 (MMP-10), prostate cancer-associated stromal fibroblasts (CAFs),extracellular matrix (ECM)

Organism: Human

Tissue: Prostate

Pathological State: Cancer

540
Screening platform for cell contact guidance based on inorganic biomaterial micro/nanotopographical gradients

Qihui Zhou, Olga Castañeda Ocampo, Carlos Guimarães, Philipp Kuhn, Theo van Kooten, and Patrick van Rijn

Applied Materials and Interfaces (ACS Publications) The Netherlands, 21 August 2017

Stem Cell Research

Key words: Biomimetic surface, high-throughput screening, inorganic biomaterials, stem cell behavior, topographical gradient

Organism: Human

Cell Line: Mesenchymal stem cells from human bone marrow (hBM-MSCs)

541
Bifidobacterium Infantis Ameliorates Chemotherapy-Induced Intestinal Mucositis Via Regulating T Cell Immunity in Colorectal Cancer Rats

Mi H, Dong Y, Zhang B, Wang H, Peter C.C.K, Gao P,Fu H, Gao Y

Celular Physiology And Biochemistry (Karger) China, 18 August 2017

Oncology

Key words: Bifidobacterium infantis, intestinal mucositis, 5-fluorouracil, oxaliplatin, CD4+CD25+Foxp3+ Tregs, CD4+CD17A+ cells, colorectal cancer

Organism: Rat

Tissue: Allograft Tumor

Pathological State: Cancer

542
An Integrated Systems Biology Approach Identifies TRIM25 as a Key Determinant of Breast Cancer Metastasis

Logan A. Walsh, Mariano J. Alvarez, Erich Y. Sabio, Marsha Reyngold, Vladimir Makarov, Suranjit Mukherjee, Ken-Wing Lee, Alexis Desrichard, Şevin Turcan, Martin G. Dalin, Vinagolu K. Rajasekhar, Shuibing Chen, Linda T. Vahdat, Andrea Califano, Timothy A. Chan

Cell Reports (Cell Press) USA, 15 August 2017

Oncology

Key words: ARACNe, MARINa, VIPER, breast, cancer, metastasis, transcription, TRIM25, EFP

Organism: Mouse

Tissue: Allograft Tumor, Lung

Pathological State: Cancer

543
Impact of Type III Secretion Effectors and of Phenoxyacetamide Inhibitors of Type III Secretion on Abscess Formation in a Mouse Model of Pseudomonas aeruginosa Infection

Bryan J. Berubea, Katherine R. Murphya, Matthew C. Torhanc, Nicholas O. Bowlinc, John D. Williamsc, Terry L. Bowlinc, Donald T. Moirc and Alan R. Hausera,b

Antimicrobial Agents and Chemotherapy (American Society for Microbiology) USA, 14 August 2017

Microbiology

Key words: Pseudomonas aeruginosa, abscesses, neutrophils, phenoxyacetamide inhibitors, type III secretion

Organism: Mouse

Tissue: Liver, Spleen

Pathological State: Abscess

544
Effects of sulfur mustard on mesenchymal stem cells

Annette Schmidt, Dirk Steinritz, Simone Rothmiller, Horst Thiermann, A. Michael Scherer

Toxicology Letters (Elsevier) Germany, 14 August 2017

Toxicology

Key words: Sulfur mustard, mesenchymal stem cells, senescence, apoptosis, proliferation

Organism: Human

Cell Line: Mesenchymal stem cells from human bone marrow (hBM-MSCs)

545
Attenuation of Follicular Helper T Cell–Dependent B Cell Hyperactivity by Abatacept Treatment in Primary Sjögren's Syndrome

Gwenny M. Verstappen,Petra M. Meiners,Odilia B. J. Corneth,Annie Visser,Suzanne Arends,Wayel H. Abdulahad,Rudi W. Hendriks,Arjan Vissink,Frans G. M. Kroese,Hendrika Bootsma

Arthritis & Rheumatology (Wiley) The Netherlands, 13 August 2017

Rheumatology

Key words: CTLA-4Ig, CD4+ T cell , Sjögren's syndrome, marker ICOS

Organism: Human

Pathological State: Sjögren's Syndrome

546
Role of glial-cell-derived neurotrophic factor in salivary gland stem cell response to irradiation

Xiaohong Peng, Kärt Varendi, Martti Maimets, Jaan-Olle Andressoo, Rob P.Coppes

Radiotherapy and Oncology (Elsevier) The Netherlands, 04 August 2017

Oncology

Key words: Salivary glands, GDNF, stem cells, spheres, radiation-induced xerostomia

Organism: Human

Tissue: Salivary Gland

547
Traditional Chinese medicine Danggui Buxue Tang inhibits colorectal cancer growth through induction of autophagic cell death

ST Chen, TY Lee, TH Tsai, YC Huang, YC Lin, CP Lin, HR Shieh, ML Hsu, CW Chi, MC Le, HH Chang, YJ Chen

Oncotarget (Impact Journals) Taiwan, 03 August 2017

Oncology

Key words: Danggui Buxue Tang, colorectal cancer, autophagy, traditional Chinese medicine, mammalian target of rapamycin (mTOR)

Organism: Mouse

Tissue: Colon, Xenograft Tumor

Pathological State: Cancer

548
The Prognostic Role of T1 Mapping Sequences: Can T1 Mapping Parameters Have a Role in Risk Stratification?

EY Choi, CH Park, TH Kim

Cardiovascular Imaging Asia (Kamje Press) South Korea, 31 July 2017

Cardiology

Key words: Cardiac magnetic resonance imaging; T1 mapping; Prognosis

Organism: Human

Tissue: Heart

549
Inhibition of colony stimulating factor-1 receptor abrogates microenvironment-mediated therapeutic resistance in gliomas

D Yan, J Kowal, L Akkari, A J Schuhmacher, J T Huse, B L West and J A Joyce

Oncogene (Nature) USA, Switzerland, 31 July 2017

Oncology

Key words: Glioblastomas, tumor microenvironment (TME)-mediated extrinsic resistance, PDGF-B-driven proneural glioma mouse model

Organism: Mouse

Tissue: Brain

Pathological State: Cancer

550
Parathyroid hormone regulates fates of murine osteoblast precursors in vivo

DH Balani, N Ono, HM Kronenberg

The Journal of Clinical Investigation (American Society for Clinical Investigation) USA, 31 July 2017

Stem Cell Research

Key words: Parathyroid hormone, osteoblast precursors, bone biology, stem cells

Organism: Mouse

Tissue: Bone

551
Transglutaminase 2 Inhibition Reverses Mesenchymal Transdifferentiation of Glioma Stem Cells by Regulating C/EBPβ Signaling

Jinlong Yin, Young Taek Oh, Jeong-Yub Kim, Sung Soo Kim, Eunji Choi, Tae Hoon Kim, Jun Hee Hong, Nakho Chang, Hee Jin Cho, Jason K. Sa, Jeong Cheol Kim, Hyung Joon Kwon, Saewhan Park, Weiwei Lin, Ichiro Nakano, Ho-Shin Gwak, Heon Yoo, Seung-Hoon Lee, Jeongwu Lee, Jong Heon Kim, Soo-Youl Kim, Do-Hyun Nam, Myung-Jin Park and Jong Bae Park

Cancer Research (AACR Publications) South Korea, 28 July 2017

Oncology

Key words: Necrosis, glioblastoma, transglutaminase 2 (TGM2), transcription factors (TF)

Organism: Mouse

Tissue: Brain

Pathological State: Cancer

552
CD103+ tumor-infiltrating lymphocytes are tumor-reactive intraepithelial CD8+ T cells associated with prognostic benefit and therapy response in cervical cancer

Fenne L. Komdeur, Thalina M. Prins, Stephanie van de Wall, Annechien Plat, G. Bea A. Wisman, Harry Hollema, Toos Daemen , David N. Church, Marco de Bruyn, The Netherlands and Hans W. Nijman

OncoImmunology (Taylor and Francis) The Netherlands, 24 July 2017

Oncology

Key words: CD103, cervical cancer, intraepithelial T cells, therapeutic vaccination, tumor-infiltrating lymphocytes

Organism: Human

Tissue: Uterus

Pathological State: Cancer

553
Fasting metabolism modulates the interleukin-12/interleukin-10 cytokine axis

Johannes J. Kovarik, Elisabeth Kernbauer, Markus A. Hölzl, Johannes Hofer, Guido A. Gualdoni, Klaus G. Schmetterer, Fitore Miftari, Yury Sobanov, Anastasia Meshcheryakova, Diana Mechtcheriakova, Nadine Witzeneder, Georg Greiner, Anna Ohradanova-Repic, Petra Waidhofer-Söllner, Marcus D. Säemann, Thomas Decker, Gerhard J. Zlabinge

PLoS One (PLOS) Austria, 24 July 2017

Immunology

Key words: Cell metabolism, mammalian target of rapamycin (mTOR), interleukin (IL)-12 and anti-inflammatory IL-10

Organism: Mouse

Tissue: Liver, Spleen

554
Precision cut lung slices as test system for candidate therapeutics in organophosphate poisoning

Julia Herbert, Horst Thiermann, Franz Worek,Timo Wille

Toxicology (Elsevier) Germany, 22 July 2017

Toxicology

Key words: Chemical warfare agents, nerve agents, pesticide,lung, PCLS, precision cut lung slices

Organism: Rat

Tissue: Lung

555
Large-scale 3-dimensional quantitative imaging of tissues: state-of-the-art and translational implications

SethWinfree, Michael J.Ferkowicz, Pierre C.Dagher, Katherine J.Kelly, Michael T.Eadon, Timothy A.Sutton, Troy A.Markel, Mervin C.Yoder, Kenneth W.Dunn, Tarek M.El-Achkar

Translational Research (Elsevier) USA, 22 July 2017

Medical Imaging

Key words: 2D2 dimensional, 3D3 dimensional, LSM- light sheet microscopy, IHCS- imaging high content screening, VTEA -Volumetric tissue exploration and analysis, 3DTC-3 dimensional tissue cytometry

556
Neuron-Specific Fluorescence Reporter-Based Live Cell Tracing for Transdifferentiation of Mesenchymal Stem Cells into Neurons by Chemical Compound

Do Won Hwang, Hyun Woo Kwon, Jaeho Jang, Hee Jung Jung, Kwang Rok Kim, and Dong Soo Lee

Stem Cells International (Hindawi Publishing Corporation) South Korea, 20 July 2017

Stem Cell Research

557
Strategies to develop endogenous stem cell-recruiting bioactive materials for tissue repair and regeneration

Settimio Pacelli, Sayantani Basu, Jonathan Whitlow, Aparna Chakravarti, Francisca Acost, Arushi Varshney, Saman Modaresia, Cory Berkland, Arghya Paul

Advanced Drug Delivery Reviews (Elsevier) USA, 19 July 2017

Regenerative Medicine

Key words: Stem cell homing, growth factor delivery, chemoattractant gradients, endothelialization, extracellular matrix, bone graft substitutes, myocardial regeneration

Organism: Human

Cell Line: Human mesenchymal stem cells (hMSCs)

558
The c.1085A>G genetic variant of CSF1R gene regulates tumor immunity by altering the proliferation, polarization, and function of macrophages

Yu-Min Yeh, Shan-Ju Hsu, Peng-Chan Lin, Keng-Fu Hsu, Pei-Ying Wu, Wu-Chou Su, Jang-Yang Chang and Meng-Ru Shen

Clinical Cancer Research (AACR Publications) Taiwan, 19 July 2017

Oncology

Key words: Tumor, CSF1R, low VEGF expression, altering the polarization and function of macrophages

Organism: Human

Tissue: Colon, Ovaries, Endometrium

Pathological State: Cancer

559
Production of reactive persulfide species in chronic obstructive pulmonary disease

Tadahisa Numakura, Hisatoshi Sugiura, Takaaki Akaike, Tomoaki Ida, Shigemoto Fujii, Akira Koarai, Mitsuhiro Yamada, Katsuhiro Onodera, Yuichiro Hashimoto, Rie Tanaka, Kei Sato, Yutaka Shishikura, Taizou Hirano, Satoru Yanagisawa, Naoya Fujino, Tatsuma Okazaki, Tsutomu Tamada, Yasushi Hoshikawa, Yoshinori Okada, Masakazu Ichinose

Thorax (BMJ Journals) Japan, 19 July 2017

Pulmonology

Key words: Oxidative Stress

Organism: Human

Tissue: Lung

Pathological State: Chronic Obstructive Pulmonary Disease

560
MicroRNA 155-deficiency leads to decreased autoantibody levels and reduced severity of nephritis and pneumonitis in pristaneinduced lupus

Harald Leiss, Wilhelm Salzberger, Barbara Jacobs, Irina Gessl, Nicolas Kozakowski, Stephan Bluml, Antonia Puchner, Attila Kiss, Bruno K. Podesser, Josef S. Smolen,Georg H. Stummvoll

PLoS One (PLOS) Austria, 18 July 2017

Immunology

Key words: Systemic lupus, miR155-deficient, PBS-injected mice, glomerulonephritis, pneumonitis

Organism: Mouse

Tissue: Kidney

Pathological State: Lupus

561
Analysis of cysteine-X-cysteine motif chemokine ligands 9, 10, and 11, their receptor CXCR3, and their possible role on the recruitment of immune cells at the maternal–conceptus interface in pigs†

Jisoo Han, Min Jeong Gu, Inkyu Yoo, Yohan Cho,i Hwanhee Jang, Minjeong Kim, Cheol-Heui Yun, Hakhyun Ka

Biology of Reproduction (Oxford University Press) South Korea, 15 July 2017

Immunology

Key words: Pig, pregnancy, uterus, endometrium, CXCL9, CXCL10, CXCL11

Organism: Human

Tissue: Endometrium

Pathological State: Cancer

562
Expansion of BCR/ABL1+ cells requires PAK2 but not PAK1

Leo Edlinger, Angelika Berger-Becvar, Ingeborg Menzl, Gregor Hoermann, Georg Greiner, Eva Grundschober, Zsuzsanna Bago-Horvath, Wael Al-Zoughbi, Gerald Hoefler, Christine Brostjan, Lars Gille, Richard Moriggl, Andreas Spittler, Veronika Sexl, Andrea Hoelbl-Kovacic

British Journal of Haematology (Wiley) Austria, 14 July 2017

Oncology

Key words: The p21-activated kinases (PAKs), BCR/ABL1+ haematopoietic malignancy, leukaemic cells

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

563
Placental homing peptide-microRNA inhibitor conjugates for targeted enhancement of intrinsic placental growth signaling

F Beards, LE Jones, J Charnock, K Forbes, LK Harris

Theranostics (NCBI) UK, 14 July 2017

Reproductive Medicine

Key words: fetal growth restriction, IGF-II, microRNA, placenta, proliferation, pregnancy

Organism: Human

Tissue: Placenta

564
RIP3 attenuates the pancreatic damage induced by deletion of ATG7

Xiaodong Zhou, Li Xie, Leizhou Xia, Frank Bergmann, Markus W Büchler, Guido Kroemer, Thilo Hackert and Franco Fortunato

Cell Death & Disease (Nature) Germany, 13 July 2017

Gastroenterology

Key words: Pancreatitis, Rip3, acinar cells, autophagy and necroptosis

Organism: Human, Mouse

Tissue: Pancreas

565
Small cell lung cancer: model of circulating tumor cell tumorospheres in chemoresistance

Lukas Klameth, Barbara Rath, Maximilian Hochmaier, Doris Moser, Marlene Redl, Felicitas Mungenast, Katharina Gelles, Ernst Ulsperger, Robert Zeillinger and Gerhard Hamilton

Scientific Reports (Nature) Austria, 13 July 2017

Oncology

Key words: Small cell lung cancer (SCLC), circulating tumor cells (CTCs), Ki67 and carbonic anhydrase 9 (CAIX)

Organism: Human

Tissue: Lung

Pathological State: Cancer

566
Tailor-made purified human platelet lysate concentrated in neurotrophins for treatment of Parkinson's disease

Ming-Li Choua, Joe-Wei Wu, Flore Gouel, Aurélie Jonneaux, Kelly Timmerman, Ting-Yi Renn, Charlotte Laloux, Hung-Ming Chang, Liang-Tzung Lin, Jean-Christophe Devedjian, David Devos , Thierry Burnou

Biomaterials (Elsevier) Taiwan, 12 July 2017

Biological Materials

Key words: Platelet lysate, neuroprotection, parkinson, MPTP, neurotrophins, growth factors

Organism: Mouse

Tissue: Brain

567
CCAAT/enhancer-binding protein delta promotes intracellular lipid accumulation in M1 macrophages of vascular lesions

Hong-Yue Lai, Ling-Wei Hsu, Hsin-Hwa Tsai, Yu-Chih Lo, Shang-Hsun, Yang Ping-Yen Liu, Ju-Ming Wang

Cardiovascular Research (Oxford University Press) Taiwan, 11 July 2017

Cardiology

Key words: CEBPD, inflammation, macrophages, PTX3, statins

Organism: Mouse

Pathological State: Vascular lesions

Cell Line: Macrophages and nile red-positive cells

568
Instructing cells with programmable peptide DNA hybrids

Ronit Freeman, Nicholas Stephanopoulos, Zaida Álvarez, Jacob A Lewis, Shantanu Sur, Chris M Serrano, Job Boekhoven, Sungsoo S. Lee and Samuel I. Stupp

Nature Communications (Nature) USA, 10 July 2017

Cell Biology

Key words: Native extracellular matrix, peptide-DNA (P-DNA)

Organism: Mouse

Cell Line: NIH-3T3 mouse embryonic fibroblasts

569
Synthetic lethal genetic interactions between Rad54 and PARP-1 in mouse development and oncogenesis

Mirella Tanori, Arianna Casciati, Francesco Berardinelli, Simona Leonardi, Emanuela Pasquali, Francesca Antonelli, Barbara Tanno, Paola Giardullo, Alessandro Pannicelli, Gabriele Babini, Ilaria De Stefano, Antonella Sgura, Mariateresa Mancuso, Anna Saran, and Simonetta Pazzaglia

Oncotarget (Impact Journals) Italy, 07 July 2017

Oncology

Key words: cerebellum, expression profiles, medulloblastoma, apoptosis, senescence

Organism: Mouse

Tissue: Brain

Pathological State: Cancer

570
A novel in vitro model of villitis of unknown etiology demonstrates altered placental hormone and cytokine profile

Hayley Derricott, Alexander E.P. Heazell, Susan L. Greenwood, Rebecca L. Jones

American Journal of Reproductive Immunology (Wiley) UK, 06 July 2017

Reproductive Medicine

Key words: Placental dysfunction, villitis of unknown etiology, T cell, fetal growth restriction

Organism: Human

Cell Line: Placental explant culture

571
Tyrosine Kinase Expressed in Hepatocellular Carcinoma, TEC, Controls Pluripotency and Early Cell Fate Decisions of Human Pluripotent Stem Cells via Regulation of Fibroblast Growth Factor-2 Secretion

Tereza Vanova, Zaneta Konecna, Zuzana Zbonakova, Giuseppe La Venuta, Karolina Zoufalova, Sarka Jelinkova,Miroslav Varecha, Vladimir Rotrekl, Pavel Krejci, Walter Nickel, Petr Dvorak, Michaela Kunova Bosakova

Stem Cells (Wiley) Czech Republic, 06 July 2017

Stem Cell Research

Key words: Human pluripotent stem cells (hPSCs), fibroblast growth factor (FGF) receptors, hepatocellular carcinoma (TEC)

Organism: Human

Cell Line: hPSCs (Human pluripotent stem cells)

572
Increased migration of antigen presenting cells to newly-formed lymphatic vessels in transplanted kidneys by glycol-split heparin

Ditmer T. Talsma, Kirankumar Katta, Miriam Boersema, Saritha Adepu,Annamaria Naggi, Giangiacomo Torri, Coen Stegeman, Gerjan Navis, Harry van Goor,Jan-Luuk Hillebrands,Saleh Yazdani, Jacob van den Born

PLoS One (PLOS) The Netherlands, 30 June 2017

Transplantation Medicine

Key words: Chronic renal transplant, lymphatic chemokine-proteoglycan, renal graft

Organism: Rat

Tissue: Kidney

Pathological State: Organ Transplantation

573
Keratinocytes produce IL-17c to protect peripheral nervous systems during human HSV-2 reactivation

Tao Peng, R. Savanh Chanthaphavong, Sijie Sun, James A. Trigilio, Khamsone Phasouk, Lei Jin, Erik D. Layton, Alvason Z. Li, Colin E. Correnti, Willem De van der Schueren, Julio Vazquez, Diana R. O’Day, Ian A. Glass, David M. Knipe, Anna Wald, Lawrence Corey, Jia Zhu

Journal Of Experimental Medicine (Rockefeller University Press) USA, 29 June 2017

Neuroscience

Key words: Herpes simplex virus (HSV), keratinocytes, IL-17c , nervous system

Organism: Human

Tissue: Skin

Cell Line: Keratinocytes

574
Interaction of tankyrase and peroxiredoxin II is indispensable for the survival of colorectal cancer cells

Dong Hoon Kang, Doo Jae Lee, Sunmi Lee, So-Young Lee, Yukyung Jun, Yerin Kim, Youngeun Kim, Ju-Seog Lee, Dae-Kee Lee, Sanghyuk Lee, Eek-Hoon Jho, Dae-Yeul Yu and Sang Won Kang

Nature Communications (Nature) South Korea, 28 June 2017

Oncology

Key words: Colon cancer, mechanisms of disease

Organism: Mouse

Tissue: Small Intestine

575
Hinokitiol up-regulates miR-494-3p to suppress BMI1 expression and inhibits self-renewal of breast cancer stem/progenitor cells

Shih-Ming Chen, Bing-Yen Wang, Che-Hsin Lee, Hsueh-Te Lee, Jung-Jung Li, Guan-Ci Hong, Yu-Chieh Hung, Peng-Ju Chien, Che-Ying Chang, Li-Sung Hsu, and Wen-Wei Chang

Oncotarget (Impact Journals) Taiwan, 27 June 2017

Oncology

Key words: hinokitiol, miR-494-3p, BMI1, breast cancer, cancer stem cells

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

576
The bile acid receptor FXR attenuates acinar cell autophagy in chronic pancreatitis

Xiaodong Zhou, Li Xie, Frank Bergmann, Volker Endris, Oliver Strobel, Markus W Büchler, Guido Kroemer, Thilo Hackert and Franco Fortunato

Cell Death Discovery (Nature) Germany, 19 June 2017

Gastroenterology

Key words: Apoptosis, chronic pancreatitis, macroautophagy, necroptosis

Organism: Human, Mouse

Tissue: Pancreas

Pathological State: Pancreatitis

577
Breviscapine (BVP) inhibits prostate cancer progression through damaging DNA by minichromosome maintenance protein-7 (MCM-7) modulation

Yang-boGuan, Dong-rongYang, Shao-junNong, JianNi, Chun-huiHu, JianLi, JinZhu, Yu-xiShan

Biomedicine and Pharmacotherapy (Elsevier) China, 17 June 2017

Oncology

Key words: Breviscapine, human prostate cancer, DNA damage, MCM-7, Apoptosis

Organism: Human, Mouse

Tissue: Prostate, Xenograft Tumor

Pathological State: Cancer

578
Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation

Pounami Samadder, Tereza Suchánková, Ondřej Hylse, Prashant Khirsariya, Fedor Nikulenkov, Stanislav Drápela, Nicol Straková, Petr Vaňhara, Kateřina Vašíčková, Hana Kolářová, Lucia Binó, Miroslava Bittová, Petra Ovesná, Peter Kollár, Radek Fedr, Milan Ešner, Josef Jaroš, Aleš Hampl, Lumír Krejčí, Kamil Paruch and Karel Souček

Molecular Cancer Therapeutics (AACR Publications) Czech Republic, 15 June 2017

Oncology

Key words: Tumor cells, serine threonine kinase, DNA antimetabolites

Organism: Human, Mouse

Tissue: Skin, Xenograft Tumor

Pathological State: Cancer

579
Inhibition of the NOD-like receptor protein 3 inflammasome is protective in juvenile influenza A virus infection

Bria M. Coates, imageKelly L. Staricha, imageNandini Ravindran, imageClarissa M. Koch, imageYuan Cheng, imageJennifer M. Davis, imageDale K. Shumaker and imageKaren M. Ridge

Frontiers in Immunology (Frontiers Media S.A.) USA, 10 June 2017

Immunology

Key words: Inhibition of the NOD-Like Receptor Protein 3 Inflammasome Is Protective in Juvenile Influenza A Virus Infection

Organism: Mouse

Tissue: Lung

Pathological State: Virus Infection

580
Clinical significance of the estrogen-modifying enzymes steroid sulfatase and estrogen sulfotransferase in epithelial ovarian cancer

Felicitas Mungenast, Stefanie Aust, Ignace Vergote, Adriaan Vanderstichele, Jalid Sehouli, Elena Braicu, Sven Mahner, Dan Cacsire Castillo-Tong, Robert Zeillinger, and Theresia Thalhammer1

Oncology Letters (Spandidos Publications) Austria, Belgium, Germany, 03 June 2017

Oncology

Key words: pithelial ovarian cancer, estrogen, estrogen metabolizing enzymes, STS, sulfotransferase, SULT1E1, E2, ovarian cancer

Organism: Human

Tissue: Ovaries

Pathological State: Cancer

581
Mutant Mice With Calcium-Sensing Receptor Activation Have Hyperglycemia That Is Rectified by Calcilytic Therapy

Valerie N Babinsky, Fadil M Hannan, Reshma D Ramracheya, Quan Zhang, M Andrew Nesbit, Alison Hugill, Liz Bentley , Tertius A Hough , Elizabeth Joynson Michelle Stewart, Abhishek Aggarwal, Maximilian Prinz-Wohlgenannt, Caroline M Gorvin, Enikö Kallay, Sara Wells, Roger D Cox , Duncan Richards, Patrik Rorsman, Rajesh V Thakker

Endocrinology (Oxford University Press) UK, 02 June 2017

Endocrinology

Key words: Calcium-Sensing Receptor, CaSR, Hyperglycemia, Calcilytic Therapy, glucose homeostasis, Diabetes

Organism: Mouse

Tissue: Xenograft Tumor, Pancreas

Pathological State: Cancer

582
Resveratrol Pretreatment Attenuates Concanavalin A-induced Hepatitis through Reverse of Aberration in the Immune Response and Regenerative Capacity in Aged Mice

Tse-Hung Huang, Chin-Chang Chen, Hsuan-Miao Liu, Tzung-Yan Lee and Sue-Heui Shieh

Scientific Reports (Nature) Taiwan, 02 June 2017

Immunology, Virology

Key words: Age-related autoimmune hepatitis, cell senescence, apoptosis, concanavalin A (Con A),

Organism: Mouse

Tissue: Liver

583
Extracellular matrix hydrogel derived from human umbilical cord as a scaffold for neural tissue repair and its comparison with extracellular matrix from porcine tissues

Zuzana Kočí, Karel Výborný, Jana Dubišová, Irena Vacková, Aleš Jäger, Oleg Lunov, Klára Jiráková, and Šárka Kubinová

Tissue Engineering Part C (Mary Ann Liebert Inc.) Czech Republic, 01 June 2017

Regenerative Medicine

Key words: Hydrogel, Umbilical Cord, Neural Tissue Repair, Extracellular Matrix, Porcine Tissues

Organism: Rat

Tissue: Spinal Cord

Cell Line: Dorsal root ganglia

584
Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation

Andrea E. Calvert, Alexandra Chalastanis, Yongfei Wu, Lisa A. Hurley, Fotini M. Kouri, Yingtao Bi, Maureen Kachman, Jasmine L. May, Elizabeth Bartom, Youjia Hua, Rama K. Mishra, Gary E. Schiltz, Oleksii Dubrovskyi, Andrew P. Mazar, Marcus E. Peter, Hongwu Zheng, C. David James, Charles F. Burant, Navdeep S. Chandel, Ramana V. Davuluri, Craig Horbinski, Alexander H. Stegh

Cell Reports (Cell Press) USA, 30 May 2017

Oncology

Key words: wild-type IDH1; GBM; metabolism; differentiation; NADPH; lipids; reactive oxygen species (ROS); EGFR; targeted therapy

Organism: Mouse

Pathological State: Cancer

Cell Line: GIC-20 (Glioma initiating cells)

585
Automated Image Analysis of HER2 Fluorescence In Situ Hybridization to Refine Definitions of Genetic Heterogeneity in Breast Cancer Tissue

Gedmante Radziuviene, Allan Rasmusson, Renaldas Augulis, Daiva Lesciute-Krilaviciene, Aida Laurinaviciene, Eduard Clim, and Arvydas Laurinavicius

BioMed Research International (Hindawi Publishing Corporation) Lithuania, Austria, 28 May 2017

Medical Image Analysis

Key words: Automated Image Analysis, HER2 FISH, Genetic Heterogeneity, Breast Cancer

Organism: Human

Tissue: Breast

Pathological State: Cancer

586
Galangin ameliorates cisplatin-induced nephrotoxicity by attenuating oxidative stress, inflammation and cell death in mice through inhibition of ERK and NF-kappaB signaling

Yu-Ching Huang, Ming-ShiunTsai, Pei-Chi Hsieh, Jheng-Hong Shih, Tsu-Shing Wang, Yi-Chun Wang, Ting-Hui Lin, Sue-Hong Wang

Toxicology and Applied Pharmacology (Elsevier) China, 27 May 2017

Oncology

Key words: Cisplatin nephrotoxicity; ERK; Galangin; Inflammation; NF-κB; Oxidative stress

Organism: Mouse

Tissue: Kidney

Pathological State: Kidney Injury

587
Hepatic IFIT3 predicts interferon-α therapeutic response in patients of hepatocellular carcinoma

Yingyun Yang,Ye Zhou,Jin Hou,Chunmei Bai,Zhenyang Li,Jia Fan,Irene O.L. Ng,Weiping Zhou,Huichuan Sun,Qiongzhu Dong,Joyce M.F. Lee,Chung-Mau Lo,Kwan Man,Yun Yang,Nan Li,Guoshan Ding,Yizhi Yu,Xuetao Cao

Hepatology (Wiley) China, 26 May 2017

Oncology

Key words: Adjuvant interferon-α (IFN-α), hepatocellular carcinoma (HCC), IFIT3,

Organism: Human

Tissue: Liver

Pathological State: Cancer

588
QUICK FIRE CASES- SESSION III

European Heart Journal (Oxford University Press) Denmark, 25 May 2017

Cardiology

Key words: Myocardium, diagnosis, fire - disaster,s fire - physical, phenomenon cardiac, mri

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

589
SIRT3-Mediated Dimerization of IDH2 Directs Cancer Cell Metabolism and Tumor

Xianghui Zou, Yueming Zhu, Seong-Hoon Park, Guoxiang Liu, Joseph O'Brien, Haiyan Jiang and David Gius

Cancer Research (AACR Publications) USA, 23 May 2017

Oncology

Key words: Isocitrate dehydrogenase IDH2, α-ketoglutarate,cancer cells, SIRT3

Organism: Human

Tissue: Breast

Pathological State: Cancer

590
Single allele Lmbrd1 knockout results in cardiac hypertrophy

Tseng LT, Lin CL, Pan KH, Tzen KY, Su MJ, Tsai CT, Li YH, Li PC, Chiang FT, Chang SC, Chang MF

Journal of the Formosan Medical Association (Elsevier) Taiwan, 23 May 2017

Cardiology

Key words: Cardiac hypertrophy, Disease animal model, Gene knockout, Mouse Lmbrd1 gene, Human LMBRD1 gene, LMBD1 protein

Organism: Mouse

Tissue: Heart

Pathological State: Hypertrophy

591
MicroRNA-146a governs fibroblast activation and joint pathology in arthritis

Victoria Saferdinga, Antonia Puchnera, Eliana Goncalves-Alvesa, Melanie Hofmanna, Michael Bonellia, Julia S. Brunnerb, Emine Sahinb, Birgit Niederreitera, Silvia Hayera, Hans P. Kienera, Elisa Einwallnerc, Ramzi Nehmard, Raphael Carapitod, Philippe Georgeld, Marije I. Koenderse, Mark Boldinf, Gernot Schabbauerb, Mariola Kurowska-Stolarskag, Günter Steinera, h, Josef S. Smolena, Kurt Redlicha, Stephan Blüml

Journal of Autoimmunity (Elsevier) Austria, 22 May 2017

Rheumatology

Key words: Synovial fibroblasts, miR-146a, tumor necrosis factor (TNF) receptor, factor 6 (TRAF6), osteoprotegerin (OPG)

Organism: Human

Tissue: Bone

Pathological State: Rheumatoid Arthritis

592
Significance of B10 cell in patients with thymoma complicated with myasthenia gravis

Y Lu, F Meng, Y Yang, L Li, D Wang, Y Cui, S Dong, W Wang

Oncotarget (Impact Journals) China, 17 May 2017

Oncology

Key words: regulatory B cell, B10 cell, thymoma, myasthenia gravis, autoimmune abnormality

Organism: Human

Tissue: Thymus

Pathological State: Cancer

593
Enhanced Bruton's Tyrosine Kinase Activity in Peripheral Blood B Lymphocytes From Patients With Autoimmune Disease

Odilia B. J. Corneth,Gwenny M. P. Verstappen,Sandra M. J. Paulissen,Marjolein J. W. de Bruijn,Jasper Rip,Melanie Lukkes,Jan Piet van Hamburg,Erik Lubberts,Hendrika Bootsma,Frans G. M. Kroese,Rudi W. Hendriks

Arthritis & Rheumatology (Wiley) The Netherlands, 10 May 2017

Rheumatology

Key words: Bruton's tyrosine kinase (BTK), B cell receptor (BCR), Sjögren's syndrome (SS), BTK phosphorylation

Organism: Human

Tissue: Salivary Gland

Pathological State: Sjögren's Syndrome

594
Hyaluronan keeps mesenchymal stem cells quiescent and maintains the differentiation potential over time

Tzyy Yue Wong,Chiung-Hsin Chang,Chen-Hsiang Yu,Lynn L. H. Huang

Aging Cell (Wiley) Taiwan, 04 May 2017

Stem Cell Research

Key words: Hyaluronan (HA), mesenchymal stem cells (MSCs), cellular aging, human placenta-derived MSCs (PDMSC)

Organism: Human

Cell Line: Human mesenchymal stem cells (hMSCs)

595
CD1b-autoreactive T cells contribute to hyperlipidemia-induced skin inflammation in mice

Sreya Bagchi, Ying He, Hong Zhang, Liang Cao, Ildiko Van Rhijn, D. Branch Moody, Johann E. Gudjonsson, and Chyung-Ru Wang

Journal of Clinical Investigation (American Society for Clinical Investigation) USA, 02 May 2017

Immunology

Key words: Autoimmunity, Immunology

Organism: Mouse

Tissue: Heart, Skin

596
A novel histone deacetylase inhibitor TMU-35435 enhances etoposide cytotoxicity through the proteasomal degradation of DNA-PKcs in triple-negative breast cancer

Yuan-Hua Wu, Chi-Wei Hong, Yi-Ching Wang, Wei-Jan Huang, Ya-Ling Yeh, Bour-Jr Wang1, Ying-Jan Wang, Hui-Wen Chiu

Cancer Letters (Elsevier) Taiwan, 24 April 2017

Oncology

Key words: DNA damage, DNA repair, Ubiquitin–proteasome system, Triple-negative breast cancer

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

597
Cytotoxicity of Natural Killer Cells Activated Through NKG2D Contributes to the Development of Bronchiolitis Obliterans in a Murine Heterotopic Tracheal Transplant Model

T. Kawakami,K. Ito,Y. Matsuda,M. Noda,A. Sakurada,Y. Hoshikawa,Y. Okada,K. Ogasawara

American Journal of Transplantation (Wiley) Japan, 21 April 2017

Transplantation Medicine

Key words: Basic (laboratory) research/science, lung transplantation/pulmonology, bronchiolitis obliterans (BOS), natural killer (NK) cells/NK receptors

Organism: Mouse

Tissue: Lung

Pathological State: Organ Transplantation

598
Two different, mutually exclusively distributed, TP53 mutations in ovarian and peritoneal tumor tissues of a serous ovarian cancer patient: indicative for tumor origin?

Nyamdelger Sukhbaatar, Anna Bachmayr-Heyda, Katharina Auer, Stefanie Aust, Simon Deycmar, Reinhard Horvat and Dietmar Pils

Molecular Case Studies (CSH Press) Austria, 14 April 2017

Oncology

Key words: Mutually exclusive p53 mutations in ovarian cancer

Organism: Human

Tissue: Ovaries

Pathological State: Cancer

599
Immunomodulatory Magnetic Microspheres for Augmenting Tumor-Specific Infiltration of Natural Killer (NK) Cells

Wooram Park , Andrew C. Gordon, Soojeong Cho, Xiaoke Huang, Kathleen R. Harris, Andrew C. Larson, and Dong-Hyun Kim

Applied Materials and Interfaces (ACS Publications) USA, 13 April 2017

Oncology

Key words: And image-guided therapy, cancer immunotherapy interferon-gamma (IFN-γ), microspheres, natural killer (NK) cells infiltration

Organism: Human

600
Extravillous Trophoblast and Endothelial Cell Crosstalk Mediates Leukocyte Infiltration to the Early Remodeling Decidual Spiral Arteriole Wall

Ruhul H. Choudhury, Caroline E. Dunk, Stephen J. Lye, John D. Aplin, Lynda K. Harris and Rebecca L. Jones

The Journal of Immunology (American Association of Immunologists) UK, Canada, 10 April 2017

Immunology

Key words: Decidual spiral arteriole (SpA), uterine decidual NK (dNK) cells, extravillous trophoblasts (EVTs), chemokines

Organism: Human

Tissue: Endometrium

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