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On May 3rd 2020, TissueGnostics surpassed 1,500 scientific reference publications

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 Most of the 1500 research publications referencing TissueGnostics (over 50%) originated in the United States, Austria, Germany, Taiwan (China) and mainland China.

  

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Customer Publications (A total of 1580 papers published)

1001
Effect of 1,25-dihydroxyvitamin D3 on the Wnt pathway in non-malignant colonic cells

Charlotte Gröschel, Abhishek Aggarwal, Samawansha Tennakoon, Julia Höbaus, Maximilian Prinz-Wohlgenannt, Brigitte Marian, Petra Heffeter, Walter Berger, Eniko Kállay

The Journal of Steroid Biochemistry and Molecular Biology (Elsevier) Austria, 14 March 2015

Oncology

Key words: 1,25-Dihydroxyvitamin D3, colorectal cancer, chemoprevention, wnt pathway, LGR5

Organism: Human

Tissue: Colon

Pathological State: Cancer

1002
Vimentin regulates activation of the NLRP3 inflammasome

Gimena dos Santos, Micah R. Rogel, Margaret A. Baker, James R. Troken, Daniela Urich, Luisa Morales-Nebreda, Joseph A. Sennello, Mikhail A. Kutuzov, Albert Sitikov, Jennifer M. Davis, Anna P. Lam, Paul Cheresh, David Kamp, Dale K. Shumaker, G. R. Scott Budinger and Karen M. Ridge

Nature Communications (Nature) USA, 12 March 2015

Cell Biology

Key words: Cytoskeletal proteins, Inflammasome, NOD-like receptors, Respiratory tract diseases

Organism: Mouse

Tissue: Heart, Lung

1003
Nitric Oxide Prevents Alveolar Senescence and Emphysema in a Mouse Model

Amanda E. Boe, Mesut Eren, Luisa Morales-Nebreda, Sheila B. Murphy, G. R. Scott Budinger, Gökhan M. Mutlu, Toshio Miyata, Douglas E. Vaughan

PLoS One (PLOS) USA, Japan, 10 March 2015

Pulmonology

Key words: Nω-nitro-L-arginine methyl ester, alveolar tissue destruction, plasminogen activator inhibitor-1

Organism: Mouse

Tissue: Lung

Pathological State: Chronic Obstructive Pulmonary Disease

1004
Clinical improvement in psoriasis with specific targeting of interleukin-23

Tamara Kopp, Elisabeth Riedl, Christine Bangert, Edward P. Bowman, Elli Greisenegger, Ann Horowitz, Harald Kittler, Wendy M. Blumenschein, Terrill K. McClanahan, Thomas Marbury, Claus Zachariae, Danlin Xu, Xiaoli Shirley Hou, Anish Mehta, Anthe S. Zandvliet, Diana Montgomery, Frank van Aarle and Sauzanne Khalilieh

Nature (Nature) Austria, USA, Denmark, 09 March 2015

Dermatology

Key words: Psoriasis, interleukin-23

1005
Induction of c-Cbl contributes to anti-cancer effects of HDAC inhibitor in lung cancer

TT Wei, YC Lin, PH Lin, JY Shih, CW Chou, WJ Huang, YC Yang, PW Hsiao, CC Chen

Oncotarget (Impact Journals) Taiwan, 08 March 2015

Oncology

Key words: c-Cbl, EGFR, HDAC inhibitors, lung cancer

Organism: Mouse

Tissue: Lung

Pathological State: Cancer

1006
Active vitamin D potentiates the anti-neoplastic effects of calcium in the colon: A cross talk through the calcium-sensing receptor

Abhishek Aggarwal, Julia Höbaus, Samawansha Tennakoon, Maximilian Prinz-Wohlgenannt, João Graça, Sally A. Price, Petra Heffeter, Walter Berger, Sabina Baumgartner-Parzer, Enikö Kállay

The Journal of Steroid Biochemistry and Molecular Biology (Elsevier) Austria, UK, 07 March 2015

Oncology

Key words: Calcium-sensing receptor, Colon cancer, Calcium, Vitamin D, Chemoprevention, Calcimimetic

Organism: Mouse

Tissue: Colon

1007
Zileuton, 5-Lipoxygenase Inhibitor, Acts as a Chemopreventive Agent in Intestinal Polyposis, by Modulating Polyp and Systemic Inflammation

Elias Gounaris, Michael J. Heiferman, Jeffrey R. Heiferman, Manisha Shrivastav, Dominic Vitello, Nichole R. Blatner, Lawrence M. Knab, Joseph D. Phillips, Eric C. Cheon, Paul J. Grippo, Khashayarsha Khazaie, Hidayatullah G. Munshi, David J. Bentrem

PLoS One (PLOS) USA, 06 March 2015

Oncology

Key words: Calcium-sensing receptor, tumor suppressor, colorectal cancer, colon, calcium, calcimimetic, calcilytic

Organism: Mouse

Tissue: Small Intestine

Pathological State: Cancer

1008
Disruption of ​STAT3 signalling promotes ​KRAS-induced lung tumorigenesis

Beatrice Grabner, Daniel Schramek, Kristina M. Mueller, Herwig P. Moll, Jasmin Svinka, Thomas Hoffmann, Eva Bauer, Leander Blaas, Natascha Hruschka, Katalin Zboray, Patricia Stiedl, Harini Nivarthi, Edith Bogner, Wolfgang Gruber, Thomas Mohr, Ralf Harun Zwick, Lukas Kenner, Valeria Poli, Fritz Aberger, Dagmar Stoiber, Gerda Egger, Harald Esterbauer, Johannes Zuber, Richard Moriggl, Robert Eferl, Balázs Gy?rffy, Josef M. Penninger, Helmut Popper ,Emilio Casanova

Nature Communications (Nature) Austria, USA, Italy, Hungary, 03 March 2015

Oncology

Key words: Interleukin-6, oncostatin-M, epidermal growth factor, Lung cancer

Organism: Human

Tissue: Lung

Pathological State: Cancer

1009
16 Dectin-2 is essentially involved in innate immune response of experimental arthritis

V Stögner, T Shvets, B Niederreiter, M Koenders, WB van den Berg, JS Smolen, K Redlich, S Hayer

Annals of the Rheumatic Diseases (BMJ Journals) Austria, The Netherlands, 01 March 2015

Rheumatology

Key words: C-type lectin receptor Dectin-2, Toll-like receptors, myeloid cells

Organism: Mouse

Pathological State: Rheumatoid Arthritis

1010
Comparative Proteomic Analysis Reveals Activation of Mucosal Innate Immune Signaling Pathways during Cholera

Crystal N. Ellis,Regina C. LaRocquea, Taher Uddin, Bryan Krastins, Leslie M. Mayo-Smith, David Sarracino, Elinor K. Karlsson, Atiqur Rahman, Tahmina Shirin, Taufiqur R. Bhuiyan, Fahima Chowdhury, Ashraful Islam Khan, Edward T. Ryan,, Stephen B. Calderwood, Firdausi Qadri Jason B. Harris

Infection and Immunity (ASM) USA, Bangladesh, 01 March 2015

Immunology

Key words: Tissue microarray, Tissue cores, Population studies, Virtual microscopy, Data exchange, Standards Validation studies, Quality assurance, Donor block, Recipient block, Multitumo,r Tissue microarray, Progression tissue microarray, Prognosis tissue microarray, Normal tissue microarray, Frozen tissue microarray, Cell line tissue microarray, Xenograft tissue microarray, Cutting edge matrix assembly tissue microarray, Immunohistochemistry , Chromogenic in situ hybridization (CISH), Fluorescent in situ hybridization (FISH), Quantum dots, Multiplex immunoblotting, Hierarchical clustering analysis, Hierarchical naïve, Bayes model, Random forest clustering

Organism: Human

Tissue: Small Intestine

Pathological State: Bacterial Infection

1011
EVI1 promotes tumor growth via transcriptional repression of MS4A3

Gerwin Heller, Anna Rommer, Katarina Steinleitner, Julia Etzler, Hubert Hackl, Petra Heffeter, Erwin Tomasich, Martin Filipits, Birgit Steinmetz, Thais Topakian, Simone Klingenbrunner, Barbara Ziegler, Andreas Spittler, Sabine Zöchbauer-Müller, Walter Berger, Rotraud Wieser

Journal of Hematology and Oncology (Springer) Austria, 01 March 2015

Oncology

Key words: EVI1, MS4A3, Transcriptional repression, Myeloid leukemia, Tumor growth

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

1012
Loss of GDF10/BMP3b as a prognostic marker collaborates with TGFBR3 to enhance chemotherapy resistance and epithelial-mesenchymal transition in oral squamous cell carcinoma

Chieh-Wen Cheng, Jenn-Ren Hsiao, Chi-Chen Fan, Yu-Kang Lo, Chi-Yuan Tzen, Li-Wha Wu, Wei-Yu Fang, Ann-Joy Cheng, Chung-Hsing Chen, I-Shou Chang, Shih Sheng Jiang, Jang-Yang Chang, Alan Yueh-Luen Lee

Molecular Carcinogenesis (Wiley) Taiwan, 01 March 2015

Oncology

Key words: Growth differentiation factor-10, transforming growth factor-β (TGF-β) superfamily, oral squamous cell carcinoma

Organism: Human

Tissue: Mucosa

Pathological State: Cancer

1013
Poly(lactide-co-glycolide) microspheres for MRI-monitored delivery of sorafenib in a rabbit VX2 model

Jeane Chena, Sarah B. White, Kathleen R. Harris, Weiguo Li, Jonathan W.T. Yap, Dong-Hyun Kim, Robert J. Lewandowski, Lonnie D. Shea, Andrew C. Larson

Biomaterials (Elsevier) USA, 25 February 2015

Nanomedicine

Key words: Sorafenib, hepatocellular carcinoma, poly(lactide-co-glycolide), magnetic resonance imaging

Organism: Rabbit

Tissue: Liver, Stomach, Lung

1014
Regulatory T cell-deficient scurfy mice develop systemic autoimmune features resembling lupus-like disease

Eva N Hadaschik, Xiaoying Wei, Harald Leiss, Britta Heckmann, Birgit Niederreiter, Günter Steiner, Walter Ulrich, Alexander H Enk, Josef S Smolen, Georg H Stummvoll

Arthritis Research and Therapy (BioMed Central) Germany, China, Austria, 23 February 2015

Rheumatology

Key words: Systemic lupus erythematosus, severe interface dermatitis, arthritis, mesangioproliferative glomerulonephritis

Organism: Mouse

Tissue: Bone, Connective Tissue

Pathological State: Lupus

1015
The calcium-sensing receptor: A promising target for prevention of colorectal cancer

Abhishek Aggarwal, Maximilian Prinz-Wohlgenannt, Samawansha Tennakoona, Julia Höbaus, Cedric Boudot, Romuald Mentaverri, Edward M. Brown, Sabina Baumgartner-Parzer, Enikö Kállay

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (Elsevier) Austria, France, USA, 18 February 2015

Oncology

Key words: Calcium-sensing receptor, tumor suppressor, colorectal cancer, colon, calcium, calcimimetic, calcilytic

Organism: Human

Pathological State: Cancer

Cell Line: Caco2 cells, HT29 cells

1016
MRI visible drug eluting magnetic microspheres for transcatheter intra-arterial delivery to liver tumors

DH Kim, J Chen, RA Omary, AC Larson

Theranostics (NCBI) USA, 07 February 2015

Oncology, Nanomedicine

Key words: MRI, microspheres, liver tumors

Organism: Rat

Tissue: Liver

Pathological State: Cancer

1017
Tissue Microarray

Myra L. Wilkerson, Stephen M. Hewitt

Handbook of Practical Immunohistochemistry (Springer) USA, 05 February 2015

Biological Methods

Key words: Tissue microarray, tissue cores, population studies, virtual microscopy, data exchange, standards, validation studies, quality assurance, donor block, recipient block, multitumor, tissue microarray, progression tissue microarray, prognosis tissue microarray, normal tissue microarray, frozen tissue microarray, cell line tissue microarray, xenograft tissue microarray, cutting edge matrix assembly tissue microarray, immunohistochemistry, chromogenic in situ hybridization (CISH), fluorescent in situ hybridization (FISH), quantum dots, multiplex immunoblotting, hierarchical clustering analysis, hierarchical naïve Bayes model, random forest clustering

1018
Generation of an anti-EpCAM antibody and epigenetic regulation of EpCAM in colorectal cancer

Mei-Ying Liao, Mark Yen-Ping Kuo, Tung-Ying Lu, Yi-Ping Wang, Han-Chung Wu

International Journal of Oncology (Spandidos Publications) Taiwan, 05 February 2015

Oncology

Key words: epigenetic regulation, EpCAM, colorectal cancer

Organism: Human

Tissue: Colon

Pathological State: Cancer

1019
Extracellular matrix expansion by cardiac magnetic resonance T1 mapping- validation with myocardial biopsy

Andreas Kammerlander, Caroline Tufaro, Alina F Bachmann, Beatrice A Marzluf, Stefan Aschauer, Andreas Greiser, Diana Bonderman, Julia Mascherbauer

Journal of Cardiovascular Magnetic Resonance (Springer) Austria, Germany, 03 February 2015

Cardiology

Key words: Cardiology, angiology, imaging/radiology

Organism: Human

Tissue: Heart

Pathological State: Heart Failure

1020
Distinct in vitro properties of embryonic and extraembryonic fibroblast-like cells are reflected in their in vivo behavior following grafting in the adult mouse brain

Costa R, Bergwerf I, Santermans E, De Vocht N, Praet J, Daans J, Le Blon D, Hoornaert C, Reekmans K, Hens N, Goossens H, Berneman Z, Parolini O, Alviano F, Ponsaerts P.

Cell Transplantation (SAGE Journals) Italy, 01 February 2015

Transplantation Medicine

Key words: Fetal membrane-derived stromal cells, Embryonic fibroblasts, Immunomodulation, Transplantation, Brain, Angiogenesis

Organism: Mouse

Tissue: Brain

1021
The expression of thymic stromal lymphopoietin in primary tumors of breast cancer is associated with prognosis

Yu H, Yang J, Li Y, Jiao S

Chinese journal of cellular and molecular immunology (NCBI) China, 01 February 2015

Oncology

Key words: Rythymic stromal lymphopoietin, disease-free survival, Univariate LOG-RANK

Organism: Human

Tissue: Breast

Pathological State: Cancer

1022
Biomarkers in Lung Diseaes: from Pathogenesis to Prediction to New Therapies: A-kinase-anchoring proteins coordinate inflammatory responses to cigarette smoke in airway smooth muscle

Wilfred J. Poppinga, Irene H. Heijink, Laura J. Holtzer, Philipp Skroblin, Enno Klussmann, Andrew J. Halayko, Wim Timens, Harm Maarsingh, Martina Schmidt

American Journal of Physiology (APS Journals) The Netherlands, Germany, Canada, USA, 30 January 2015

Pulmonology

Key words: Compartmentalization, A-kinase-anchoring protein, inflammation, cyclic AMP, chronic obstructive pulmonary disease

Organism: Human

Cell Line: Human bronchial ASM cells

1023
The Major Birch Pollen Allergen Bet v 1 Induces Different Responses in Dendritic Cells of Birch Pollen Allergic and Healthy Individuals

Ursula Smole, Christian Radauer, Nina Lengger, Martin Svoboda, Neil Rigby, Merima Bublin, Sonja Gaier, Karin Hoffmann-Sommergruber, Erika Jensen-Jarolim, Diana Mechtcheriakova , Heimo Breiteneder

PLoS One (PLOS) USA, Austria, UK, 30 January 2015

Allergy Research

Key words: Allergens, cytokines, gene expression, pollen, immune response, fluorescence competition, monocytes, chemokines

Organism: Human

Pathological State: Allergy

Cell Line: iMoDCs ( immature monocyte-derived dendritic cells)

1024
Correlation of circular RNA abundance with proliferation–exemplified with colorectal and ovarian cancer, idiopathic lung fibrosis, and normal human tissues

Anna Bachmayr-Heyda, Agnes T. Reiner, Katharina Auer, Nyamdelger Sukhbaatar, Stefanie Aust, Thomas Bachleitner-Hofmann, Ildiko Mesteri, Thomas W. Grunt, Robert Zeillinger and Dietmar Pils

Scientific Reports (Nature) Austria, 27 January 2015

Oncology

Key words: Cancer genetics, Epigenetics

Organism: Human

Tissue: Colon

Pathological State: Cancer

1025
Mapping spatial heterogeneity in the tumor microenvironment: a new era for digital pathology

Andreas Heindl, Sidra Nawaz, Yinyin Yuan

Nature (Nature) UK, 19 January 2015

Oncology

Key words: Tumor, digital pathology, mapping, spatial heterogeneity

1026
Loss of mitochondrial exo/endonuclease EXOG affects mitochondrial respiration and induces ROS-mediated cardiomyocyte hypertrophy

Wardit Tigchelaar, Hongjuan Yu, Anne Margreet de Jong, Wiek H. van Gilst, Pim van der Harst, B. Daan Westenbrink, Rudolf A. de Boer, Herman H. W. Silljé

Cell Physiology (APS Journals) The Netherlands, China, 15 January 2015

Cardiology

Key words: Cardiomyocytes, hypertrophy, mitochondria, mitochondrial respiration, ROS

Organism: Rat

Pathological State: Hypertrophy

Cell Line: NRVCs (neonatal rat ventricular cardiomyocytes)

1027
Down-regulation of TIMP-1 inhibits cell migration, invasion, and metastatic colonization in lung adenocarcinoma

Ying-Hua Chang, Yi-Jen Chiu, Hung-Chi Cheng, Fang-Ju Liu, Wu-Wei Lai, Hsiao-Jen Chang, Pao-Chi Liao

Tumor Biology (Springer) Taiwan, USA, 13 January 2015

Oncology

Key words: TIMP-1, migration, invasion,metastatic colonization, pericellular fibronectin assembly, lung adenocarcinoma

Organism: Human

Tissue: Lung

Pathological State: Cancer

1028
Localization of sunitinib, its metabolites and its target receptors in tumour-bearing mice: a MALDI-MS imaging study

S Torok, A Vegvari, M Rezeli, T E Fehniger, J Tovari, S Paku, V Laszlo, B Hegedus, A Rozsas, B Dome, G. Marko-Varga

British Journal of Pharmacology (Wiley) Hungary, Austria, Sweden, Japan, 12 January 2015

Pharmacology

Key words: C-26 adenocarcinoma cells, matrix-assisted laser desorption ionization MS imaging, VEGF receptor-2

Organism: Mouse

Tissue: Allograft Tumor, Colon

Pathological State: Cancer

1029
Epitope topography controls bioactivity in supramolecular nanofibers

S Sur, F Tantakitti, JB Matson, SI Stupp

Biomaterials Science (Royal Society of Chemistry) USA, 09 January 2015

Nanomedicine

Key words: Epitope topography, bioactivity, nanofibers

Organism: Mouse

Cell Line: Mouse embryonic fibroblasts

1030
A multidisciplinary approach unravels early and persistent effects of X-ray exposure at the onset of prenatal neurogenesis

Tine Verreet, Roel Quintens, Debby Van Dam, Mieke Verslegers, Mirella Tanori, Arianna Casciati, Mieke Neefs, Liselotte Leysen, Arlette Michaux, Ann Janssen, Emiliano D’Agostino, Greetje Vande Velde, Sarah Baatout, Lieve Moons, Simonetta Pazzaglia, Anna Saran, Uwe Himmelreich, Peter Paul De Deyn, Mohammed Abderrafi Benotmane

Journal of Neurodevelopmental Disorders (Springer) Belgium, Italy, The Netherlands, 09 January 2015

Neuroscience

Key words: Apoptosis, Brain development, Cognitive dysfunction, MRI, Radiation

Organism: Mouse

Tissue: Brain

1031
SMAD2 and p38 signaling pathways act in concert to determine XY primordial germ cell fate in mice

Q Wu, K Fukuda, M Weinstein, JM Graff, Y Saga

Development (The Company of Biologists) Japan, USA, 01 January 2015

Developmental Biology

Key words: sex determination,,Meiosis, SMAD2 signaling, p38 signaling, Nanos2, Smad2/3 conditional knockout mice

Organism: Mouse

Tissue: Testis

1032
Zinc and pioglitazone effects on ovaries and endometrium in diabetes

C Gales, C Zamfir, B Stoica, M Nechifor

Farmacia () Romania, 01 January 2015

Reproductive Medicine

Key words: diabetes, zinc, pioglitazone, endometrium

Organism: Rat

Tissue: Uterus, Ovaries

Pathological State: Diabetes

1033
Relationship between Apoptosis Imaging and Radioiodine Therapy in Tumor Cells with Different Sodium Iodide Symporter Gene Expression

Kyung Oh Jung, Hyewon Youn, Young-Hwa Kim, Seunghoo Kim, Juri Na, Yong-Il Kim, Jin Woo Park, Keon Wook Kang, Dong Soo Lee, June-Key Chung

Molecular Imaging (SAGE Journals) South Korea, 01 January 2015

Oncology

Key words: Apoptosis Imaging, Radioiodine Therapy, Tumor Cells, Sodium Iodide Symporter

Organism: Human

Pathological State: Cancer

Cell Line: Human colorectal adenocarcinoma cell line (HT29)

1034
Comparative assessment of biocompatibility of NiCr and CoCr alloys used in metalfused-to-ceramic technology

RALUCA MONICA COMANEANU, VIOLETA HANCU, HORIA MIHAIL BARBU, COSTIN COMAN, COSMIN MIHAI COTRUT, MIHAIL TARCOLEA, ANA MARIA HOLICOV, ALINA ORMENISAN

REVISTA DE CHIMIE () Romania, 01 January 2015

Biological Methods

Key words: NiCr and CoCr alloys, metal-fused-to-ceramic restoration, biomaterial, biocompatibility

Organism: Human

Cell Line: Human Osteosarcoma cell line (HOS)

1035
MRI-Monitored Intra-Tumoral Injection of Iron-Oxide Labeled Clostridium novyi-NT Anaerobes in Pancreatic Carcinoma Mouse Model

Linfeng Zheng, Zhuoli Zhang, Khashayarsha Khazaie, Saurabh Saha, Robert J. Lewandowski, Guixiang Zhang, Andrew C. Larson

PLoS One (PLOS) USA, China, 30 December 2014

Oncology

Key words: Magnetic resonance imaging, catheters, anaerobic bacteria, gram staining, fluorescence microscopy, transmission electron microscopy, in vivo imaging, nanoparticles

Organism: Mouse

Tissue: Pancreas

Pathological State: Cancer

1036
Coronary Neutrophil Extracellular Trap Burden and Deoxyribonuclease Activity in ST-Elevation Acute Coronary Syndrome Are Predictors of ST-Segment Resolution and Infarct Size

Andreas Mangold, Sherin Alias, Thomas Scherz, Thomas Hofbauer, Johannes Jakowitsch, Adelheid Panzenböck, Daniel Simon, Daniela Laimer, Christine Bangert, Andreas Kammerlander, Julia Mascherbauer, Max-Paul Winter, Klaus Distelmaier, Christopher Adlbrecht, Klaus T. Preissner, Irene M. Lang

Circulation Research (AHA Journals) Germany, Austria, 29 December 2014

Cardiology

Key words: Atherosclerosis, coronary occlusion, coronary thrombosis, deoxyribonucleases, extracellular traps, myocardial infarction, neutrophils

Organism: Human

Tissue: Blood Vessels

1037
PIAS1 is a crucial factor for prostate cancer cell survival and a valid target in docetaxel resistant cells

Martin Puhr, Julia Hoefer, Hannes Neuwirt, Iris E. Eder, Johann Kern, Georg Schäfer, Stephan Geley, Isabel Heidegger, Helmut Klocker, Zoran Culig

Oncotarget (Impact Journals) Austria, 24 December 2014

Oncology

Key words: prostate cancer, PIAS1, docetaxel, chemotherapy resistance, apoptosis

Organism: Human

Tissue: Prostate

Pathological State: Cancer

1038
TLR4-mediated inflammation promotes foam cell formation of vascular smooth muscle cell by upregulating ACAT1 expression

Y-W Yin, S-Q Liao, M-J Zhang, Y Liu, B-H Li, Y Zhou, L Chen, C-Y Gao, J-C Li and L-L Zhang

Cell Death & Disease (Nature) China, 18 December 2014

Cardiology

Key words: Atherosclerosis, Cell signalling, Foam cells, Inflammation

Organism: Mouse

Tissue: Blood Vessels

1039
Epidermal Elafin Expression Is an Indicator of Poor Prognosis in Cutaneous Graft-versus-Host Disease

Marie-Charlotte Brüggen, Peter Petzelbauer, Hildegard Greinix, Emmanuel Contassot, Dragana Jankovic, Lars French, Gérard Socié, Werner Rabitsch, Zoya Kuzmina, Peter Kalhs, Robert Knobler, Georg Stingl, Georg Stary

Journal of Investigative Dermatology (Elsevier) Austria, Switzerland, France, 18 December 2014

Dermatology

Key words: Epidermal elafin, cutaneous graft, host disease

Organism: Human

Tissue: Skin

Pathological State: Graft-versus-Host Disease

1040
The cognitive defects of neonatally irradiated mice are accompanied by changed synaptic plasticity, adult neurogenesis and neuroinflammation

Stefan J Kempf, Arianna Casciati, Sonja Buratovic, Dirk Janik, Christine von Toerne, Marius Ueffing, Frauke Neff, Simone Moertl, Bo Stenerlöw, Anna Saran, Michael J Atkinson, Per Eriksson, Simonetta Pazzaglia, Soile Tapio

Molecular Neurodegeneration (BioMed Central) Germany, Italy, Sweden, 16 December 2014

Neuroscience

Key words: Dendritic spines, hippocampus, cortex, CREB, miR-132, ionising radiation, proteomics, Rac1, cofilin, alzheimer

Organism: Mouse

Tissue: Brain

1041
Quantitative measurement of cancer tissue biomarkers in the lab and in the clinic

Daniel E Carvajal-Hausdorf, Kurt A Schalper, Veronique M Neumeister and David L Rimm

Laboratory Investigation (Nature) USA, 15 December 2014

Oncology

Key words: Breast cancer

1042
Carboxylated Short Single-Walled Carbon Nanotubes But Not Plain and Multi-Walled Short Carbon Nanotubes Show in vitro Genotoxicity

Maria Mrakovcic, Claudia Meindl, Gerd Leitinger, Eva Roblegg, Eleonore Fröhlich

Toxicological Sciences (Oxford University Press) Austria, 10 December 2014

Toxicology

Key words: Carbon nanotubes, cytotoxicity, genotoxicity, oxidative stress, HPRT mutation, assay micronucleus

Cell Line: V79 cells

1043
Pharmacodynamic and Therapeutic Investigation of Focused Ultrasound-Induced Blood-Brain Barrier Opening for Enhanced Temozolomide Delivery in Glioma Treatment

Hao-Li Liu, Chiung-Yin Huang, Ju-Yu Chen, Hay-Yan Jack Wang, Pin-Yuan Chen, Kuo-Chen Wei

PLoS One (PLOS) Taiwan, 09 December 2014

Oncology

Key words: Cancer treatment, magnetic resonance imaging, glioma, drug therapy, pharmacodynamics, blood plasma, liquid chromatography-mass spectrometry, glioma cells

Organism: Mouse

Tissue: Brain

Pathological State: Cancer

1044
Effects of azithromycin and tanomastat on experimental bronchiolitis obliterans

Katharina Krenn, Matthias Gmeiner, Patrick Paulus, Nezir Sela, Linda Torres, Karin Zins, Gerhard Dekan, Seyedhossein Aharinejad

Journal of thoracic and cardiovascular surgery (Elsevier) Austria, Germany, 04 December 2014

Pulmonology

Key words: Azithromycin, tanomastat

Organism: Rat

Tissue: Lung

Pathological State: Bronchiolitis Obliterans

1045
Clec4n Is Essentially Involved in Innate Immune Response of Experimental Arthritis

V. Stögner, T. Shvets, B. Niederreiter, M. Koenders, W. van den Berg,J. Smolen, K. Redlich, S. Hayer

Rehabilitation () The Netherlands, 04 December 2014

Rheumatology

1046
TonEBP/NFAT5 regulates ACTBL2 expression in biomechanically activated vascular smooth muscle cells

M Hödebeck, C Scherer, AH Wagner, M Hecker, T Korff

Frontiers in Physiology (Frontiers Media S.A.) Germany, 03 December 2014

Physiology

Organism: Human

Cell Line: HUASMCs

1047
Selective delivery of IFN-γ to renal interstitial myofibroblasts: a novel strategy for the treatment of renal fibrosis

Fariba Poosti, Ruchi Bansal, Saleh Yazdani, Jai Prakash, Eduard Post, Pieter Klok, Jacob van den Born, Martin H. de Borst, Harry van Goor, Klaas Poelstra, Jan-Luuk Hillebrands

FASEB Journal (FASEB) The Netherlands, 02 December 2014

Nephrology

Key words: Drug targeting, PDGFRβ, kidney, unilateral ureteral obstruction

Organism: Mouse

Cell Line: NIH3T3 Fibroblasts

1048
Prognostic Significance and Determinants of the 6-minute Walk Test in Patients with Pulmonary Hypertension Associated with Heart Failure and Preserved Ejection Fraction

C Tufaro, J Mascherbauer, F Duca, S Aschauer, A Panzenboeck, C Bangert, D Laimer, I Lang, D Bonderman

Pneumologie (Thieme) Austria, 01 December 2014

Pulmonology

Key words: Exertional fatigue, dyspnea, pulmonary hypertension, heart failure with preserved ejection fraction

1049
Stat5 gene dosage in T cells modulates CD8+ T-cell homeostasis and attenuates contact hypersensitivity response in mice

H. Nivarthi, M. Prchal-Murphy, A. Swoboda, M. Hager, M. Schlederer, L. Kenner, J. Tuckermann, V. Sexl, R. Moriggl, O. Ermakova

Allergy (Wiley) Austria, Germany, Italy, 30 November 2014

Allergy Research

Key words: Allergic contact dermatitis, Stat5,T cells

Organism: Mouse

Tissue: Ear

1050
Protection of Shengmai Recipe on Improving Cardiac Function and Attenuating Kidney Injury in Pressure Overload Rats

Feng-jiao Sun, Peng-wei Zhuang, Yu Wang, Jin-bao Zhang, Zhi-qiang Lu, Yan Wang, Mi-xia Zhang, Jin Wu, Zhuo Chen, Meng Sun, Yan-jun Zhang

Chinese Herbal Medicines (Elsevier) China, 27 November 2014

Cardiology

Key words: Chronic heart failure, left ventricular systolic function, myocardial fibrosis, renal ischemia lesion, Shengmai Recipe

Organism: Mouse

Tissue: Heart, Kidney

Pathological State: Kidney Injury

1051
A subset of chondrogenic cells provides early mesenchymal progenitors in growing bones

N Ono, W Ono, T Nagasawa, HM Kronenberg

Nature Cell Biology (Nature) USA, Japan, 24 November 2014

Stem Cell Research

Key words: Bone development, Mesenchymal stem cells

Organism: Mouse

Tissue: Bone

1052
CD16+ monocytes with smooth muscle cell characteristics are reduced in human renal chronic transplant dysfunction

M. Boersema, J.C. van den Born, J. van Ark, G. Harms, M.A. Seelen, M.C.R.F. van Dijk, H. van Goor, G.J. Navis, E.R. Popa, J.L. Hillebrands

Immunobiology (Elsevier) The Netherlands, 21 November 2014

Immunology

Key words: Chronic transplant dysfunction, Kidney, Monocytes, Monocyte heterogeneity, Smooth-muscle-like cells, Transplantation

Organism: Human

Tissue: Kidney

Pathological State: Renal Chronic Transplant Dysfunction

1053
CD16⁺ monocytes with smooth muscle cell characteristics are reduced in human renal chronic transplant dysfunction.

M Boersema, J van Ark, MA Seelen, MCRF van Dijk, H van Goor, GJ navis, ER Popa, JL Hillebrands

Immunobiology (Elsevier) The Netherlands, 21 November 2014

Transplantation Medicine

Key words: Chronic transplant dysfunction, Kidney, Monocytes, Monocyte heterogeneity, Smooth-muscle-like cells, Transplantation

Organism: Human

Tissue: Kidney

Pathological State: Renal Chronic Transplant Dysfunction

1054
Hepatic stellate cells secretes type I collagen to trigger epithelial mesenchymal transition of hepatoma cells

MC Yang, CJ Wang, PC Liao, CJ Yen, YS Shan

American Journal of Cancer Research (NCBI) China, Taiwan, 19 November 2014

Oncology

Key words: Hepatic stellate cell, collagen type I, epithelial-mesenchymal transition

Organism: Human

Tissue: Liver

1055
Comparison of CD163+ macrophages and CD206+ cells in lesional skin of CD30+ lymphoproliferative disorders of lymphomatoid papulosis and primary cutaneous anaplastic large-cell lymphoma

Aya Kakizaki, Taku Fujimura, Yumi Kambayashi, Sadanori Furudate, Mitsuko Kawano, Kouetsu Ogasawara, Setsuya Aiba

Acta Dermato Venereologica (Ingentaconnect) Japan, 18 November 2014

Dermatology

Key words: CD163+ Macrophages, CD206+ Cells, Skin Lesion, CD30+ LymphoproliferativeDisorders, Lymphomatoid Papulosis, Primary Cutaneous Anaplastic Large-cell Lymphoma

Organism: Human

Tissue: Skin

Pathological State: Lymphomatoid Papulosis, Cancer

1056
Effect of preemptive treatment with human umbilical cord blood-derived mesenchymal stem cells on the development of renal ischemia-reperfusion injury in mice

Hye Ryoun Jang, Ji Hyeon Park, Ghee Young Kwon, Jung Eun Lee, Wooseong Huh, Hye Jin Jin, Soo Jin Choi, Wonil Oh, Ha Young Oh, Yoon-Goo Kim

American Journal of Physiology - Renal Physiology (APS Journals) South Korea, 15 November 2014

Nephrology

Key words: Mesenchymal stem cells, inflammation, renal ischemia-reperfusion injury, human umbilical cord blood-derived mesenchymal stem cells

Organism: Mouse

Tissue: Kidney

Pathological State: Renal Ischemia-Reperfusion Injury

1057
Generation of induced pluripotent stem cells without genetic defects by small molecules

Hang-Soo Parka, Insik Hwanga, Kyung-Ah Choia, Hyesun Jeonga, Ji-Yun Leeb, Sunghoi Hong

Biomaterials (Elsevier) South Korea, 15 November 2014

Biological Materials

Key words: Induced pluripotent stem cells, small molecules, genomic stability, DNA double-strand breaks

Organism: Mouse

Cell Line: Fibroblasts and iPSCs

1058
An increase in integrin-linked kinase non-canonically confers NF-κB-mediated growth advantages to gastric cancer cells by activating ERK1/2

Po-Chun Tseng, Chia-Ling Chen, Yan-Shen Shan, Wen-Teng Chang, Hsiao-Sheng Liu, Tse-Ming Hong, Chia-Yuan Hsieh, Sheng-Hsiang Lin, Chiou-Feng Lin

Cell Communication and Signaling (Springer) Taiwan, 15 November 2014

Oncology

Key words: ILK, Cell growth, IQGAP1, ERK1/2, NK-κB

Organism: Human

Tissue: Stomach

Pathological State: Cancer

1059
No evidence of cell cycle dysregulation in mantle cell lymphoma in vivo

Niklas Vogt, Dmitriy Abramov, Karoline Koch, Neus Masqué-Soler, Monika Szczepanowski, and Wolfram Klapper

Leukemia and Lymphoma (Informa) Germany, Russia, 14 November 2014

Oncology

Key words: Mantle cell lymphoma, cyclin D1, Ki67, cell cycle, immunofluorescence

Organism: Human

Tissue: Lymphoid Tissue

Pathological State: Cancer

1060
The Patched 1 Tumor-Suppressor Gene Protects the Mouse Lens from Spontaneous and Radiation-Induced Cataract

Ilaria De Stefano, Barbara Tanno, Paola Giardullo, Simona Leonardi, Emanuela Pasquali, Francesca Antonelli, Mirella Tanori, Arianna Casciati, Simonetta Pazzaglia, Anna Saran, Mariateresa Mancuso

The American Journal of Pathology (Elsevier) Italy, 14 November 2014

Cell Biology

Key words: Epithelial-to-mesenchymal transition, lens epithelial cells, growth factor β, medulloblastoma, Gorlin syndrome

Organism: Mouse

Tissue: Eye

Pathological State: Cataract

1061
Characterization and anti-tumor effects of chondroitin sulfate–chitosan nanoparticles delivery system

Chieh-Shen Hu, Sung-Ling Tang, Chiao-Hsi Chiang, Hossein Hosseinkhani, Po-Da Hong, Ming-Kung Yeh

Journal of Nanoparticle Research (Springer) Taiwan, 07 November 2014

Oncology

Key words: Cell uptake efficiency, hepg2 cell, dox concentration, chondroitin sulfate, encapsulation efficiency, chitosan nanoparticle, anthracycline, gold nanoparticle,disaccharide, hepg2 cell line,entrapment efficiency,tumor volume

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

1062
The Pseudomonas aeruginosa type III translocon is required for biofilm formation at the epithelial barrier

Cindy S. Tran, Stephanie M. Rangel, Henrik Almblad, Arlinet Kierbel, Michael Givskov, Tim Tolker-Nielsen, Alan R. Hauser, Joanne N. Engel

PLoS Pathogens (PLOS) Uruguay, Singapore, Denmark, USA, 06 November 2014

Microbiology

Key words: Bacterial biofilms, Pseudomonas aeruginosa, Pulmonary imaging, Antibiotic resistance, Host cells Cell staining, Confocal microscopy, Mouse models

Organism: Mouse

Tissue: Lung

Pathological State: Pseudomonas Infection

1063
Pharmacological inhibition of TGFβ receptor improves Nkx2.5 cardiomyoblast-mediated regeneration

Wen-Pin Chen, Yuan-Hung Liu, Yi-Jin Ho, Sean M. Wu

Cardiovascular Research (Oxford University Press) Taiwan, USA, 01 November 2014

Regenerative Medicine

Key words: Nkx2.5, Cardiomyoblast, TGFβ, Regeneration, Myocardial infarction

Organism: Mouse

Tissue: Heart

1064
GATA2 Regulates Differentiation Of Bone Marrow-Derived Mesenchymal Stem Cells

Mayumi Kamata, Yoko Okitsu, Tohru Fujiwara, Masahiko Kanehira, Shinji Nakajima, Taro Takahashi, Ai Inoue, Noriko Fukuhara, Yasushi Onishi, Kenichi Ishizawa, Ritsuko Shimizu, Masayuki Yamamoto, Hideo Harigae

Haematologica (Ferrata Storti Foundation) Japan, 01 November 2014

Stem Cell Research

Key words: Bone marrow, stem cells

Organism: Human

Cell Line: BM-MSCs

1065
The role of cytokines and chemokines in the T-cell-mediated autoimmune process in alopecia areata

Taisuke Ito, Yoshiki Tokura

Experimental Dermatology (Wiley) Japan, 29 October 2014

Dermatology

Key words: Alopecia areata, chemokine, cytokine, immune privilege, swarm of bees

Organism: Mouse

Pathological State: Alopecia Areata

Cell Line: Th17 cells

1066
Megakaryocytes are essential for HSC quiescence through the production of thrombopoietin

Ayako Nakamura-Ishizua, Keiyo Takubo, Masato Fujioka, Toshio Suda

Biochemical and Biophysical Research Communications (Elsevier) Japan, 24 October 2014

Hematology

Key words: Megakaryocytes, hematopoietic stem cells, thrombopoietin, niche, bone marrow

Organism: Mouse

Tissue: Bone Marrow

1067
Fenretinide: A Novel Treatment for Endometrial Cancer

Navdha Mittal, Saurabh Malpani, Matthew Dyson, Masanori Ono, John S. Coon, Julie J. Kim, Julian C. Schink, Serdar E. Bulun, Mary Ellen Pavone

PLoS One (PLOS) USA, 23 October 2014

Oncology

Key words: Cancer treatment, apoptosis, uterine cancer, vitamin A, gene expression, small interfering RNAs, retinoic acid, cancer therapy

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

1068
Loss of Gsα Early in the Osteoblast Lineage Favors Adipogenic Differentiation of Mesenchymal Progenitors and Committed Osteoblast Precursors

Partha Sinha, Piia Aarnisalo, Rhiannon Chubb, Noriaki Ono, Keertik Fulzele, Martin Selig, Hamid Saeed, Min Chen, Lee S Weinstein, Paola Divieti Pajevic, Henry M Kronenberg, Joy Y Wu

Journal of Bone and Mineral Research (Wiley) USA, Finland, 20 October 2014

Rheumatology

Key words: Osteoblasts, GSA, mesenchymal progenitors, adipocytes

Organism: Mouse

Tissue: Adipose Tissue

1069
Role of fractalkine in the pathogenesis of primary Sjögren syndrome: increased serum levels of fractalkine, its expression in labial salivary glands, and the association with clinical manifestations

Jae Ho Lee, Seung-Ki Kwok, Seung Min Jung, Jennifer Lee, Jae-Seon Lee, Seung Ye Baek, Eun-Kyung Kim, Ji Hyeon Ju, Sung-Hwan Park and Ho-Youn Kim

Journal of Rheumatology (jrheum.org) South Korea, 15 October 2014

Rheumatology

Key words: SJÖGREN SYNDROME, FRACTALKINE, CX3CR1

Organism: Human

Tissue: Head and Neck

Pathological State: Cancer

1070
Langerhans cells promote early germinal center formation in response to Leishmania-derived cutaneous antigens

Nicole Zimara, Christian Florian, Maximilian Schmid, Bernard Malissen, Adrien Kissenpfennig, Daniela N. Männel, Matthias Edinger, James A. Hutchinson, Petra Hoffmann, Uwe Ritter

European Journal of Immunology (Wiley) Germany, France, UK, 13 October 2014

Immunology

Key words: B cells, follicular helper, germinal center reaction, langerhans cells, leishmania major, T cells

Organism: Human

Pathological State: Leishmaniasis

Cell Line: B-Cells

1071
The pre- and post-somatic segments of the human type I spiral ganglion neurons – Structural and functional considerations related to cochlear implantation

W. Liu, F. Edin, F. Atturo, G. Rieger, H. Löwenheime, P. Senn, M. Blumer, A. Schrott-Fischer, H. Rask-Andersen, R. Glueckert

Neuroscience (Elsevier) Sweden, Italy, Austria, Germany, Switzerland, 12 October 2014

Neuroscience

Key words: Human cochlea, spiral ganglion neurons, non-myelinated Schwann cells, laminin-ß2, collagen IV, immunohistochemistry

Organism: Human

Tissue: Ear

1072
Specific expression of OATPs in primary small cell lung cancer (SCLC) cells as novel biomarkers for diagnosis and therapy

Stefan Brenner, Lukas Klameth, d, Juliane Riha, Madeleine Schölm, Gerhard Hamilton, Erika Bajna, Christoph Ausch, Angelika Reiner, Walter Jäger, Theresia Thalhammer , Veronika Buxhofer-Ausch

Cancer Letters (Elsevier) Austria, 06 October 2014

Oncology

Key words: Small cell lung cancer (SCLC), organic anion transporting polypeptide (OATP), neurogenic marker, chemotherapy, OATP gene expression

Organism: Human

Tissue: Brain, Lung

Pathological State: Cancer

1073
TGF-β is an inducer of ZEB1-dependent mesenchymal transdifferentiation in glioblastoma that is associated with tumor invasion

JV Joseph, S Conroy, T Tomar, E Eggens-Meijer, K Bhat, S Copray, AME Walenkamp, E Boddeke, V Balasubramanyian, M Wagemakers, WFA den Dunnen and FAE Kruyt

Cell Death & Disease (Nature) The Netherlands, USA, 02 October 2014

Oncology

Key words: Cell signalling, CNS cancer, Transdifferentiation, Transforming growth factor beta

Organism: Mouse

Tissue: Brain

Pathological State: Cancer

1074
Adipose tissue–derived stromal cells inhibit TGF-β1–induced differentiation of human dermal fibroblasts and keloid scar–derived fibroblasts in a paracrine fashion

M Spiekman, E Przybyt, JA Plantinga, S Gibbs,B van der Lei, M Harmsen

Plastic and Reconstructive Surgery (Wolters Kluwer) The Netherlands, 01 October 2014

Stem Cell Research

Organism: Human

Cell Line: Dermal Fibroblasts

1075
The Inner Foreskin of Healthy Males at Risk of HIV Infection Harbors Epithelial CD4+ CCR5+ Cells and Has Features of an Inflamed Epidermal Barrier

Maria P. Lemos, Javier R. Lama, Shelly T. Karuna, Youyi Fong, Silvia M. Montano, Carmela Ganoza, Raphael Gottardo, Jorge Sanchez, M. Juliana McElrath

PLoS One (PLOS) USA, Peru, 30 September 2014

Virology

Key words: Epidermis, inflammation, membrane staining, epithelium, keratinocytes, HIV infections, circumcision HIV

Organism: Human

Tissue: Penis

1076
Late effects of local irradiation on the expression of inflammatory markers in the Arteria saphena of C57BL/6 wild-type and ApoE-knockout mice

I. Patties, B. Habelt, B. Rosin, W. Dörr, G. Hildebrandt, A. Glasow

Radiation and Environmental Biophysiscs (Springer) Germany, Austria, 27 September 2014

Immunology

Key words: A. saphe ,inflammation, irradiatin , ApoE-knockout mice, atherosclerosis, macrovasculature

Organism: Mouse

Tissue: Blood Vessels

1077
CCR9/CCL25 expression in non-small cell lung cancer correlates with aggressive disease and mediates key steps of metastasis

Pranav Gupta, Praveen K. Sharma, Hina Mir, Rajesh Singh, Nalinaksha Singh, Goetz H. Kloecker, James W. Lillard, and Shailesh Singh

Oncotarget (Impact Journals) USA, India, 25 September 2014

Oncology

Key words: CCR9, CCL25, Chemokine receptor, Non-small cell lung cancer

Organism: Human

Tissue: Lung

Pathological State: Cancer

1078
Extracellular matrix components of adipose derived stromal cells promote alignment, organization, and maturation of cardiomyocytes in vitro

Ewa Przybyt, Marja J. A. van Luyn andMartin C. Harmsen

Journal of Biomedical Materials Research (Wiley) The Netherlands, 24 September 2014

Transplantation Medicine

Key words: Myocardial infarction, cardiomyocytes, adipose derived stromal cells, extracellular matrix

Organism: Human

Cell Line: Adipose derived stromal cells

1079
Myeloid-derived suppressor cell functionality and interaction with Leishmania major parasites differ in C57BL/6 and BALB/c mice

Maximilian Schmid, Nicole Zimara, Anja Kathrin Wege, Uwe Ritter

European Journal of Immunology (Wiley) Germany, 19 September 2014

Immunology

Key words: Arginase-1, bone marrow, inducible nitric oxide synthase, leishmania major, myeloid-derived suppressor cells

Organism: Mouse

Pathological State: Bacterial Infection

Cell Line: Myeloid‐derived suppressor cells

1080
Intratracheal administration of influenza virus is superior to intranasal administration as a model of acute lung injury

Luisa Morales-Nebreda, Monica Chi, Emilia Lecuona, Navdeep S. Chandel, Laura A. Dada, Karen Ridge, Saul Soberanes, Recep Nigdelioglu, Jacob I. Sznajder, Gökhan M. Mutlu, G.R. Scott Budinger, Kathryn A. Radigan

Journal of Virological Methods (Elsevier) USA, 17 September 2014

Virology

Key words: Influenza A infection, inoculation, mice, lung injury, intratracheal, intranasal

Organism: Mouse

Tissue: Lung

Pathological State: Viral Infection

1081
Antigen-loaded dendritic cell migration: MR imaging in a pancreatic carcinoma model

Zhuoli Zhang , Weiguo Li, Daniele Procissi, Kangan Li, Alexander Y. Sheu, Andrew C. Gordon, Yang Guo, Khashayarsha Khazaie, Yi Huan, Guohong Han, Andrew C. Larson

Radiology (Radiological Society of North America) China, 15 September 2014

Oncology

Organism: Mouse

Tissue: Pancreas

Pathological State: Cancer

1082
Role of TRAP1 and estrogen receptor alpha in patients with ovarian cancer -A study of the OVCAD consortium

Stefanie Aust, Anna Bachmayr-Heyda, Petra Pateisky, Dan Tong, Silvia Darb-Esfahani, Carsten Denkert, Radoslav Chekerov, Jalid Sehouli, Sven Mahner, Toon Van Gorp, Ignace Vergote, Paul Speiser, Reinhard Horvat, Robert Zeillinger, Dietmar Pils

Molecular Cancer (Springer) Austria, Germany, Belgium, The Netherlands, 14 September 2014

Oncology

Key words: TRAP1, estrogen receptorImmunohistochemistry, prognosis, ovarian cancer

Organism: Human

Tissue: Ovaries

Pathological State: Cancer

1083
Specific roles for dendritic cell subsets during initiation and progression of psoriasis

Elisabeth Glitzner, Ana Korosec, Patrick M Brunner, Barbara Drobits, Nicole Amberg, Helia B Schonthaler, Tamara Kopp, Erwin F Wagner, Georg Stingl, Martin Holcmann,Maria Sibilia

EMBO Molecular Medicine (Wiley) Austria, Spain, 12 September 2014

Dermatology

Key words: AP-1, IL-23, langerhans cells, plasmacytoid dendritic cells, psoriasis

Organism: Human

Tissue: Skin

Pathological State: Psoriasis

1084
An Activatable Prodrug for the Treatment of Metastatic Tumors

Eun-Joong Kim, Sankarprasad Bhuniya, Hyunseung Lee, Hyun Min Kim, Chaejoon Cheong, Sukhendu Maiti, Kwan Soo Hong, Jong Seung Kim

Journal of the American Chemical Society (ACS Publications) South Korea, 11 September 2014

Oncology

Key words: Metastatic cancers, tumor cell growth, cellular imaging

Organism: Mouse

Tissue: Lung, Xenograft Tumor

Pathological State: Cancer

1085
Olfactory Receptor Patterning in a Higher Primate

Lisa F. Horowitz, Luis R. Saraiva, Donghui Kuang, Kyoung-hye Yoon, Linda B. Buck

Journal of Neuroscience (SFN) USA, 10 September 2014

Neuroscience

Key words: Macaque odorant receptor, primate trace-amine associated receptor

Organism: Monkey

Tissue: Mucosa

1086
Late inflammatory and thrombotic changes in irradiated hearts of C57BL/6 wild-type and atherosclerosis-prone ApoE-deficient mice

I. Patties, J. Haagen, W. Dörr, G. Hildebrandt, A. Glasow

Strahlentherapie und Onkologie (Springer) Germany, Austria, 09 September 2014

Radiotherapy

Key words: Irradiatio,n microvasculature, Heart Inflammation, Atheroscrosis Bestrahlung, Mikrovaskulatur, Herz Entzündung Atherosklerose

Organism: Mouse

Tissue: Heart

1087
Energy metabolism analysis reveals the mechanism of inhibition of breast cancer cell metastasis by PEG-modified graphene oxide nanosheets

Teng Zhoua, Bo Zhang, Peng Wei,Yipeng Du, Hejiang Zhou, Meifang Yu, Liang Yan, Wendi Zhang, Guangjun Nie, Chunying Chen, Yaping Tu, Taotao Wei

Biomaterials (Elsevier) China, USA, 08 September 2014

Nanomedicine

Key words: PEG-modified graphene oxide, breast cancer cell, metastasis, cytoskeletal assembly, mitochondrial oxidative phosphorylation

Organism: Mouse

Tissue: Lung

1088
STAT3β controls inflammatory responses and early tumor onset in skin and colon experimental cancer models

Francesca Marino, Valeria Orecchia, Gabriella Regis, Monica Musteanu, Beatrice Tassone, Cristina Jon, Marco Forni, Enzo Calautti, Roberto Chiarle, Robert Eferl, and Valeria Poli

American Journal of Cancer Research (NCBI) Italy, Austria, Spain, USA, 06 September 2014

Oncology

Key words: STAT3 isoforms, STAT3β, inflammation, inflammation-driven tumorigenesis, colitis-associated cancer, AOM/DSS protocol, skin tumorigenesis, DMBA/TPA protocol, genetically modified mice

Organism: Human

Tissue: Skin

Pathological State: Cancer

1089
Optimisation of the quantitative analysis of inflammatory cell infiltrates in breast cancer/Optimizarea analizei cantitative a infiltratului celular inflamator în cancerul …

AR Vrânceanu, CC Tărniceriu, D Jitaru, C Terinte, F Zugun-Eloae, E Carasevici

Revista Romana de Medicina de Laborator () Romania, 03 September 2014

Oncology

Organism: Human

Tissue: Breast

Pathological State: Cancer

1090
NEW INSIGHTS IN PULMONARY HYPERTENSION

European Heart Journal (Oxford University Press) Italy, 31 August 2014

Cardiology

1091
Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix

Leila Akkari, Vasilena Gocheva, Jemila C. Kester, Karen E. Hunter, Marsha L. Quick, Lisa Sevenich, Hao-Wei Wang, Christoph Peters, Laura H. Tang, David S. Klimstra, Thomas Reinheckel, Johanna A. Joyce

Genes and Development (CSH Press) USA, Germany, 29 August 2014

Oncology

Key words: Cell invasion, cell migration, tumor microenvironment protease

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

1092
Quantitative LA-ICP-MS imaging of platinum in chemotherapy treated human malignant pleural mesothelioma samples using printed patterns as standard

M Bonta, H Lohninger, V Laszlo, B Hegedus, A Limbeck

Journal of Analytical Atomic Spectrometry (Royal Society of Chemistry) Austria, Hungary, 29 August 2014

Oncology

Organism: Human

Tissue: Lung

Pathological State: Cancer

1093
Macrophage Migration Inhibitory Factor Triggers Chemotaxis of CD74+CXCR2+ NKT Cells in Chemically Induced IFN-γ–Mediated Skin Inflammation

Chia-Yuan Hsi, Chia-Ling Chen, Yee-Shin Lin, Trai-Ming Yeh, Tsung-Ting Tsai, Ming-Yuan Hong, Chiou-Feng Lin

The Journal of Immunology (American Association of Immunologists) Taiwan, 29 August 2014

Immunology

Key words: Human NK cell, macrophage migration inhibitory factor

Organism: Human

Cell Line: Isolated primary human blood cell

1094
Vascularization of primary and secondary ossification centres in the human growth plate

Sonja M Walzer, Erdal Cetin, Ruth Grübl-Barabas, Irene Sulzbacher, Beate Rueger, Werner Girsch, Stefan Toegel, Reinhard Windhager, Michael B Fischer

BMC Developmental Biology (Springer) Austria, 28 August 2014

Developmental Biology

Key words: Growth plate, vascularization, primary ossification centres, secondary ossification centres, progenitor cells

Organism: Human

Tissue: Bone

1095
Type I interferons have opposing effects during the emergence and recovery phases of colitis

Isabella Rauch, Eva Hainzl, Felix Rosebrock, Susanne Heider, Clarissa Schwab, David Berry, Dagmar Stoiber, Michael Wagner, Christa Schleper, Alexander Loy, Tim Urich, Mathias Müller, Birgit Strobl, Lukas Kenner,Thomas Decker

European Journal of Immunology (Wiley) Austria, 25 August 2014

Immunology

Key words: Colitis, inflammation, interferons, interleukin-1, microbiota

Organism: Mouse

Tissue: Colon

Pathological State: Colitis

1096
Shock Wave Treatment Enhances Cell Proliferation and Improves Wound Healing by ATP Release-coupled Extracellular Signal-regulated Kinase (ERK) Activation

Anna M. Weihs, Christiane Fuchs, Andreas H. Teusch, Joachim Hartinger, Paul Slezak, Rainer Mittermayr, Heinz Redl§,Wolfgang G. Junger, Harald H. Sitte, Dominik Rünzler

Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) Austria, 12 August 2014

Regenerative Medicine

Key words: ATP Cell proliferation, extracellular signal-regulated kinase (ERK), signal transduction, wound healing, shock wave treatment

Organism: Rat

Tissue: Skin

1097
Histological Characterization and Quantification of Cellular Events Following Neural and Fibroblast(-Like) Stem Cell Grafting in Healthy and Demyelinated CNS Tissue

Jelle Praet, Eva Santermans, Kristien Reekmans, Nathalie de Vocht, Debbie Le Blon, Chloé Hoornaert, Jasmijn Daans, Herman Goossens, Zwi Berneman, Niel Hens, Annemie Van der Linden, Peter Ponsaert

Animal Models for Stem Cell Therapy (Springer) Belgium, 04 August 2014

Stem Cell Research

Key words: Neural stem cell, mouse embryonic fibroblasts, cell grafting, cuprizone, quantitative histology, inflammation

1098
Analysis of tumour-and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S

Lisa Sevenich, Robert L. Bowman, Steven D. Mason, Daniela F. Quail, Franck Rapaport, Benelita T. Elie, Edi Brogi, Priscilla K. Brastianos, William C. Hahn, Leslie J. Holsinger, Joan Massagué, Christina S. Leslie and Johanna A. Joyce

Nature Cell Biology (Nature) USA, 03 August 2014

Oncology

Key words: Cancer microenvironment, Metastasis

Organism: Mouse

Tissue: Brain

Pathological State: Cancer

1099
Benzyl butyl phthalate induces migration, invasion, and angiogenesis of Huh7 hepatocellular carcinoma cells through nongenomic AhR/G-protein signaling

Cheng-Fang Tsai, Tsung-Hua Hsieh, Jau-Nan Lee, Chia-Yi Hsu, Yu-Chih Wang, Feng-Jie Lai, Kung-Kai Kuo, Hua-Lin Wu, Eing-Mei Tsai and Po-Lin Kuo

BMC Cancer (Springer) Taiwan, 01 August 2014

Oncology

Key words: Phthalate, Aryl hydrocarbon receptor, Angiogenesis, Migration, Hepatocellular carcinoma

Organism: Mouse

Tissue: Liver, Xenograft Tumor

Pathological State: Cancer

1100
The vitamin D system is deregulated in pancreatic diseases

Doris Hummel, Abhishek Aggarwal, Katalin Borka, Erika Bajna, Enikö Kállay, Henrik Csaba Horváth

The Journal of Steroid Biochemistry and Molecular Biology (Elsevier) Austria, Hungary, Switzerland, 30 July 2014

Oncology

Key words: Vitamin D, CYP24A1, VDR, CaSR, chronic pancreatitis, pancreatic ductal adenocarcinoma, pancreatic cancer

Organism: Human

Tissue: Pancreas

1101
Hardware and Software

Yves Sucaet, Wim Waelput

Hardware and Software (Springer) Belgium, 23 July 2014

Medical Imaging

Key words: Digital pathology, slide scanner, tile scanner, line scanner, file format, medical imaging WSI DP MRXS NDPI SVS BIF

1102
Single Administration of p2TA (AB103), a CD28 Antagonist Peptide, Prevents Inflammatory and Thrombotic Reactions and Protects against Gastrointestinal Injury in Total-Body Irradiated Mice

Salida Mirzoeva, Tatjana Paunesku, M. Beau Wanzer, Anat Shirvan, Raymond Kaempfer, Gayle E. Woloschak, William Small Jr

PLoS One (PLOS) USA, Israel, 23 July 2014

Gastroenterology

Key words: Inflammation, ayclins, fibrinogen, macrophages, gamma rays, cytokines, infrared radiation, small intestine

Organism: Mouse

Tissue: Small Intestine, Lung, Spleen

1103
Absence of substance P and the sympathetic nervous system impact on bone structure and chondrocyte differentiation in an adult model of endochondral ossification

Tanja Niedermaira, Volker Kuhn, Fatemeh Doranehgard, Richard Stange, Britta Wieskötter, Johannes Beckmann, Philipp Salmen, Hans-Robert Springorum, Rainer H. Straub, Andreas Zimmer, Joachim Grifka, Susanne Grässel

Matrix Biology (Elsevier) Germany, Austria, 22 July 2014

Neuroscience

Key words: Substance P, sympathetic nerve fibers, fracture callus, bone structure, bone formation, bone resorption, biomechanics, endochondral ossification

Organism: Mouse

Tissue: Bone Marrow

1104
Wnt Coreceptor Lrp5 Is a Driver of Idiopathic Pulmonary Fibrosis

Anna P. Lam , Jose D. Herazo-Maya , Joseph A. Sennello , Annette S. Flozak , Susan Russell , Gökhan M. Mutlu , G. R. Scott Budinger , Ramanuj DasGupta , John Varga , Naftali Kaminski , and Cara J. Gottardi

American Journal of Respiratory and Critical Care Medicine (ATS Journals) USA, 15 July 2014

Pulmonology

Key words: lung fibrosis, Wnt/β-catenin signaling, peripheral blood mononuclear cell

Organism: Human

Tissue: Lung

Pathological State: Idiopathic Pulmonary Fibrosis

1105
Reliable Quantification of Protein Expression and Cellular Localization in Histological Sections

Michaela Schlederer, Kristina M. Mueller, Johannes Haybaeck, Susanne Heider, Nicole Huttary, Margit Rosner, Markus Hengstschläger, Richard Moriggl, Helmut Dolznig, Lukas Kenner

PLoS One (PLOS) Austria, 11 July 2014

Pathology

Key words: Image analysis, pathologists, cell staining, hepatocytes, protein expression, cytoplasmic staining, transcription factors, hepatocellular carcinoma

Organism: Mouse

1106
EpCAM is overexpressed in local and metastatic prostate cancer, suppressed by chemotherapy and modulated by MET-associated miRNA-200c/205

P Massoner, T Thomm, B Mack, G Untergasser, A Martowicz, K Bobowski, H Klocker, O Gires and M Puhr

British journal of Cancer (Nature) Austria, Germany, 03 July 2014

Oncology

Key words: Biomarkers, Cancer therapeutic resistance, Oncogenesis, Prostate cancer

Organism: Human

Tissue: Pancreas

Pathological State: Cancer

1107
Alteration in the Wnt microenvironment directly regulates molecular events leading to pulmonary senescence

Tamas Kovacs, Veronika Csongei, Diana Feller, David Ernszt, Gabor Smuk, Veronika Sarosi, Laszlo Jakab, Krisztian Kvell, Domokos Bartis Judit E. Pongracz

Aging Cell (Wiley) Hungary, UK, 01 July 2014

Cell Biology

Key words: Molecular biology of aging, pulmonary senescence, Wnt microenvironment

Organism: Human

Tissue: Lung

1108
Distinct spatial distribution of microglia and macrophages following mesenchymal stem cell implantation in mouse brain

Debbie Le Blon, Chloé Hoornaert, Jasmijn Daans, Eva Santermans, Niel Hens, Herman Goossens, Zwi Berneman, Peter Ponsaerts

Immunology and Cell Biology (Wiley) Belgium, 01 July 2014

Immunology

Organism: Mouse

Tissue: Brain

1109
Comprehensive assessment of HIV target cells in the distal human gut suggests increasing HIV susceptibility toward the anus

MJ. McElrath, K. Smythe, J. Randolph-Habecker, KR. Melton, TA. Goodpaster, S. Hughes, M. Mack, A. Sato, G. Diaz, G. Steinbach, R. Novak, M. Curlin, JD. Lord, J. Maenza, A. Duerr, N. Frahm, F. Hladik

Journal of acquired immune deficiency Syndrome (NCBI) USA, Germany, 01 July 2014

Virology

Organism: Human

Tissue: Colon

Pathological State: Viral Infection

1110
Podocalyxin-like 1 promotes invadopodia formation and metastasis through activation of Rac1/Cdc42/cortactin signaling in breast cancer cells

Cheng-Wei Lin, Min-Shiou Sun, Mei-Ying Liao, Chu-Hung Chung, Yi-Hsuan Chi, Li-Tin Chiou, John Yu, Kuo-Lung Lou, Han-Chung Wu

Carcinogenesis (Oxford University Press) Taiwan, 26 June 2014

Oncology

Key words: Podocalyxin-like 1 invadopodia, cortactin invasion metastasis

Organism: Human

Tissue: Colon, Breast

Pathological State: Cancer

1111
Memantine Alleviates Brain Injury and Neurobehavioral Deficits after Experimental Subarachnoid Hemorrhage

Chih-Yuan Huang, Liang-Chao Wang, Hao-Kuang Wang, Chia-Hsin Pan, Ya-Yun Cheng, Yan-Shen Shan, Chung-Ching Chio, Kuen-Jer Tsai

Molecular Neurobiology (Springer) Taiwan, 22 June 2014

Neuroscience

Key words: Blood-brain barrier, memantine, neuroprotection, nitric oxide synthase, subarachnoid hemorrhage

Organism: Rat

Tissue: Brain

Pathological State: Hemorrhage

1112
OP0103 Decreased Lupus Severity in Mir155 Deficient Mice

H. Leiss, W. Salzberger, I. Gessl, N. Kozakowski, S. Blüml, A. Puchner, B. Niederreiter, G. Steiner, J. Smolen, G. Stummvoll

Annals of the Rheumatic Diseases (BMJ Journals) Austria, 14 June 2014

Rheumatology

Key words: MicroRNAs, MiR155-deficient, glomerulonephritis, serum antibody, T helper cell homeostasis

Organism: Mouse

Tissue: Kidney, Lung

Pathological State: Lupus

1113
OP0300 Effect of VEGF121-Fibrin on the Expression of VEGF Receptors in Ischemic Lesions of UCD-206 Chickens, an Animal Model for Systemic Sclerosis

S. Allipour-Birgani, H. Dietrich, J. Gruber, O. Distler, A. Zisch, R. Sgonc

Annals of the Rheumatic Diseases (BMJ Journals) Austria, Switzerland, 14 June 2014

Rheumatology

Key words: Systemic sclerosis, perivascular mononuclear cell infiltration, Microvascular injury, angiogenesis, vascular endothelial cell growth factor

Organism: Chicken

Tissue: Skin

1114
An integrated approach for the systematic evaluation of polymeric nanoparticles in healthy and diseased organisms

Leopoldo Sitia, Katia Paolella, Michela Romano, Martina Bruna Violatto, Raffaele Ferrari, Stefano Fumagalli, Laura Colombo, Ezia Bello, Maria Grazia De Simoni, Maurizio D’Incalci, Massimo Morbidelli, Eugenio Erba, Mario Salmona, Davide Moscatelli, Paolo Bigini

Journal of Nanoparticle Research (Springer) Italy, Switzerland, 12 June 2014

Nanomedicine

Key words: Optical imaging, cellular uptake, protein corona, breast tumor, cell cycle phase, nu nu mouse, atomic force microscopy, lymph node, involvment, intracellular delivery, tumor vasculature

Organism: Human

Cell Line: 4T1 and MDA-MB cells

1115
A hormone-dependent feedback-loop controls androgen receptor levels by limiting MID1, a novel translation enhancer and promoter of oncogenic signaling

Andrea Köhler, Ümmühan Demir, Eva Kickstein, Sybille Krauss, Johanna Aigner, Beatriz Aranda-Orgillés, Antonios I Karagiannidis, Clemens Achmüller, Huajie Bu, Andrea Wunderlich, Michal-Ruth Schweiger, Georg Schaefer, Susann Schweiger, Helmut Klocker, Rainer Schneider

Molecular Cancer (Springer) Austria, Germany, UK, 09 June 2014

Oncology

Key words: Androgen receptor, MID1, Translation, Prostate cancer, Reciprocal regulation

Organism: Human

Tissue: Pancreas

Pathological State: Cancer

1116
B Cells and Ectopic Follicular Structures: Novel Players in Anti-Tumor Programming with Prognostic Power for Patients with Metastatic Colorectal Cancer

Anastasia Meshcheryakova, Dietmar Tamandl, Erika Bajna, Judith Stift, Martina Mittlboeck, Martin Svoboda, Denise Heiden, Stefan Stremitzer, Erika Jensen-Jarolim, Thomas Grünberger, Michael Bergmann, Diana Mechtcheriakova

PLoS One (PLOS) Austria, 06 June 2014

Immunology

Key words: B cells, immune cells, macrophages, cell staining, portal veins, colorectal cancer, DAPI staining, nuclear staining

Organism: Human

Tissue: Colon

Pathological State: Cancer

1117
Angiogenesis as prospective molecular biology technique for cancer study

Grigore T. Popa

Romanian Biotechnological Letters (University of Bucharest) Romania, 03 June 2014

Oncology

Key words: esophagus, tumor, neoangiogenesis, quantitative study

Organism: Human

Tissue: Esophagus

Pathological State: Cancer

1118
Circulating Cytokines and Alarmins Associated with Placental Inflammation in High-Risk Pregnancies

Sylvie Girard, Alexander E. P. Heazell, Hayley Derricott, Stuart M. Allan, Colin P. Sibley, Vikki M. Abrahams, Rebecca L. Jones

American Journal of Reproductive Immunology (Wiley) UK, USA, Canada, 28 May 2014

Reproductive Medicine

Key words: High-risk pregnancy, inflammation, placental dysfunction, stillbirth

Organism: Human

Tissue: Placenta

1119
A novel rat full-thickness hemi-abdominal wall/hindlimb osteomyocutaneous combined flap: influence of allograft mass and vascularized bone marrow content on vascularized composite allograft survival

Alejandro E. Ramirez, Hui-Yun Cheng3, William W. Lao, Yen-Ling Wang, Chih-Jen Wen, Christopher G. Wallace, Chih-Fan Lin, Ling-Yi Shih, Sheng-Hao Chuang and Fu-Chan Wei

Transplant International (Wiley) Taiwan, Chile, USA, 24 May 2014

Transplantation Medicine

Key words: Abdominal wall transplantation, allograft mass, allograft survival, combined flap, vascularized bone marrow, vascularized composite allotransplantation

Organism: Rat

Tissue: Whole Organism

1120
Coexpression of CD44-positive/CD133-positive cancer stem cells and CD204-positive tumor-associated macrophages is a predictor of survival in pancreatic ductal adenocarcinoma

Ya-Chin Hou, Ying-Jui Chao, Hui-Ling Tung, Hao-Chen Wang, Yan-Shen Shan

Cancer (Wiley) Taiwan, 19 May 2014

Oncology

Key words: Pancreatic ductal adenocarcinoma, cancer stem cells, tumor-associated macrophages, tissue microarrays, CD44, CD133, CD204

Organism: Human

Tissue: Pancreas

Pathological State: Cancer

1121
Cav3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage

Shin-Shiou Lin, Bing-Hsiean Tzeng,Kuan-Rong Lee, Richard J. H. Smith, Kevin P. Campbell, Chien-Chang Chen

PNAS (PNAS) Taiwan, USA, 13 May 2014

Physiology

Key words: Chondrogenesis, tracheal cartilage, mesenchymal cells, chondrocytes

Organism: Mouse

Tissue: Lung

1122
Cell cycle association and hypoxia regulation of excision repair cross complementation group 1 protein (ERCC1) in tumor cells of head and neck cancer

József Dudás, Volker H. Schartinger, Angela Romani, Gabriele Schweigl, Kristian Kordsmeyer, Patricia Irina Marta, Christoph Url, Florian Kral, Herbert Riechelmann

Tumor Biology (Springer) Austria, 12 May 2014

Oncology

Key words: Gene expression, cell cycle phase, bronchial epithelial cell, nuclear extract

Organism: Human

Tissue: Head and Neck

Pathological State: Cancer

1123
Relevance of estrogen activating STS and inactivating SULT1E1 enzymes and estrogen receptors [alpha/beta] in patients with advanced ovarian cancer

Felicitas Mungenast, Stefanie Aust, Martin Svoboda, Katharina Ocko, Lukas Klameth, Dan Cacsire Castilo-Tong, Robert Zeillinger, Toon Van Gorp, Ignace Vergote, Ioana Braicu, Jalid Sehouli, Sven Mahner, M Fogel and Theresia Thalhammer

16th European Congress of Endocrinology (Endocrine Abstracts) Austria, Belgium, Germany, Israel, 07 May 2014

Oncology

1124
A new rat model for orthotopic abdominal wall allotransplantation

WW Lao, YL Wang, AE Ramirez, HY Cheng, FC Wie

Plastic Reconstruction Surgery Global open (NCBI) Taiwan, 07 May 2014

Oncology

Organism: Rat

Tissue: Muscle

Pathological State: Allotransplantation

1125
1172 (pp34) myocardial Biopsy for the Validation of Cardiac Magnetic Resonance T1 Mapping for Quantification of Extracellular Matrix

A Kammerlander, C Tufaro, S Pfaffenberger, B Marzluf, S Aschauer, J Babayev, D Bonderman, J Mascherbauer

European Heart Journal (Oxford University Press) Austria, 01 May 2014

Cardiology

Organism: Human

Tissue: Heart

1126
A new fluorescence/PET probe for intracellular human telomerase reverse transcriptase (hTERT) using Tat peptide-conjugated antibody

Kyung Oh Jung, Hyewon Youn, Mi Jeong Kim, Keon Wook Kang, Dong Soo Lee and June-Key Chung

Journal of Nuclear Medicine () South Korea, 01 May 2014

Biological Methods

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

1127
Increase of Zinc Finger Protein 179 in Response to CCAAT/Enhancer Binding Protein Delta Conferring an Antiapoptotic Effect in Astrocytes of Alzheimer’s Disease

Shao-Ming Wang, Yi-Chao Lee, Chiung-Yuan Ko, Ming-Derg Lai, Ding-Yen Lin, Ping-Chieh Pao, Jhih-Ying Chi, Yu-Wei Hsiao, Tsung-Lin Liu, Ju-Ming Wang

Molecular Neurobiology (Springer) Taiwan, 01 May 2014

Neuroscience

Key words: Alzheimer's disease CEBPD ZNF179, astrocytes, antiapoptosis

Organism: Mouse

Tissue: Brain

Pathological State: Alzheimer’s Disease

1128
PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors

Rieko Ohki, Kozue Saito, Yu Chen, Tatsuya Kawase, Nobuyoshi Hiraoka, Raira Saigawa, Maiko Minegishi, Yukie Aita, Goichi Yanai, Hiroko Shimizu, Shinichi Yachida, Naoaki Sakata, Ryuichiro Doi, Tomoo Kosugi, Kazuaki Shimada, Benjamin Tycko, Toshihiko Tsukada, Yae Kanai, Shoichiro Sumi, Hideo Namiki, Yoichi Taya, Tatsuhiro Shibata, Hitoshi Nakagama

PNAS (PNAS) Japan, 01 May 2014

Oncology

Key words: p53 PH domain everolimus p53 target gene mTOR

Organism: Mouse

Tissue: Pancreas

Pathological State: Cancer

1129
ISAC XXII International Congress

ISAC XXII International Congress

Cytometry (Wiley) , 21 April 2014

Cytometry

1130
Epicutaneously applied Der p 2 induces a strong TH2-biased antibody response in C57BL/6 mice, independent of functional TLR4

C. Stremnitzer, K. Manzano-Szalai, P. Starkl, A. Willensdorfer, S. Schrom, J. Singer, U. Reichart, S. Akira, E. Jensen-Jarolim

Allergy (Wiley) Austria, 16 April 2014

Allergy Research

Key words: Allergic dermatitis, Der p 2, house dust mite, LPS, TLR4

Organism: Mouse

Tissue: Skin

1131
Direct comparison of the dynamics of IL-25- and ‘allergen’-induced airways inflammation, remodelling and hypersensitivity in a murine asthma model

X. J. Yao, K. W. Huang, Y. Li, Q. Zhang, J. J. Wang, W. Wang, J. Liu, Z. Lv, Y. Q. An, Y. Z. Ding, C. J. Corrigan, W. Wang, Y. C. Sun, S. Ying

Clinical and Experimental Allergy (Wiley) China, UK, 16 April 2014

Allergy Research

Key words: Asthma, IL-25, IL-25 receptor, murine model, pathogenesis, remodelling

Organism: Mouse

Tissue: Lung

Pathological State: Fibrosis

1132
Poly(lactide-co-glycolide) microspheres for MRI-monitored transcatheter delivery of sorafenib to liver tumors

Jeane Chen, Alexander Y. Sheu, Weiguo Li, Zhuoli Zhang, c, Dong-Hyun Kim, Robert J. Lewandowski, Reed A. Omary, Lonnie D. Shea, Andrew C. Larson

Journal of Controlled Release (Elsevier) USA, 13 April 2014

Oncology

Key words: Sorafenib, hepatocellular carcinoma, magnetic resonance imaging, poly(lactide-co-glycolide)

Organism: Rat

Tissue: Liver

1133
Abstract 1662: Towards automated analysis of prostate inflammatory state: Assessing density and distance of infiltrating T-cells (CD3+) to glandular structures in prostate biopsies by a new software

Radu Rogojanu, Bogdan Boghiu, Georg Schaefer, Theresia Thalhammer, Georg Steiner, Rupert Ecker, Bettina Schlick, Thomas Szekeres, Isabella Ellinger

Cancer Research (AACR Publications) Austria, Romania, 09 April 2014

Medical Image Analysis

Key words: Biopsies, automated analysis

Organism: Human

Tissue: Prostate

Pathological State: Cancer

1134
T cell-associated α4β7 but not α4β1 integrin is required for the induction and perpetuation of chronic colitis

E Kurmaeva, JD Lord, S Zhang, JR Bao, CG Kevil, MB Grisham and DV Ostanin

Mucosal Immunology (Nature) USA, 09 April 2014

Immunology

Key words: Antibody therapy, Colitis, Crohn's disease, Mucosal immunology

Organism: Human

Tissue: Colon

1135
Calcium-sensing receptor silencing in colorectal cancer is associated with promoter hypermethylation and loss of acetylation on histone 3

Irfete S. Fetahu, Julia Höbaus, Abhishek Aggarwal, Doris M. Hummel, Samawansha Tennakoon, Ildiko Mesteri, Sabina Baumgartner-Parzer, Eniko Kállay

International Journal of Cancer (Wiley) Austria, 02 April 2014

Oncology

Key words: Calcium-sensing receptor, DNA methylation, histone acetylation, histone methylation, colorectal cancer

Organism: Human

Cell Line: Coga1, Caco2 and HT29 cells

1136
Oncogenic functions of IGF1R and INSR in prostate cancer include enhanced tumor growth, cell migration and angiogenesis

I Heidegger, J Kern, P Ofer, H Klocker, P Massoner

Oncotarget (Impact Journals) Austria, 02 April 2014

Oncology

Key words: Prostate cancer, IGF targeting therapies, insulin-like growth factor receptor-1 (IGF1R), insulin receptor (INSR)

Organism: Human

Tissue: Prostate

Pathological State: Cancer

1137
Transplantation of cyclic stretched fibroblasts accelerates the wound-healing process in streptozotocin-induced diabetic mice

E Lee, DY Kim, E Chung, EA Lee, KS Park, Y Son

Cell Transplantation (SAGE Journals) South Korea, 01 April 2014

Transplantation Medicine

Key words: Cell survival, Cyclic stretch, Mechanical stimulus, Angiogenesis, Wound healing

Organism: Mouse

Pathological State: Diabetes

Cell Line: Fibroblasts

1138
Protective effect of magnesium and metformin on endometrium and ovary in experimental diabetes mellitus

C Gales, C Zamfir, D Radulescu, B Stoica, M Nechifor

Magnesium research (John Libbey) Romania, 01 April 2014

Reproductive Medicine

Key words: magnesium, endometrium, ovary, diabetes mellitus

Organism: Mouse

Pathological State: Diabetes

Cell Line: Fibroblasts

1139
Muscle–fat MRI: 1.5 tesla and 3.0 tesla versus histology

Andrew C. Smith, Todd B. Parrish, Rebecca Abbott, Mark A. Hoggarth, Karl Mendoza, Yu Fen Chen, James M. Elliott

Muscle and nerve (Wiley) USA, 28 March 2014

Medical Imaging

Key words: MRI, muscle fat infiltrates, muscle imaging, muscle/fat fraction, muscle, fat

Organism: Rabbit

Tissue: Muscle

1140
Oxygen therapy does not increase production and damage induced by reactive oxygen species in focal cerebral ischemia

Li Suna, Guido Wolfertsb, Roland Veltkamp

Neuroscience Letters (Elsevier) Germany, 28 March 2014

Neuroscience

Key words: Cerebral ischemia, oxygen therapy, HBO, reactive oxygen species, SOD2

Organism: Mouse

Tissue: Brain

Pathological State: cerebral ischemia

1141
Myofibroblasts in Murine Cutaneous Fibrosis Originate From Adiponectin-Positive Intradermal Progenitors

Roberta Goncalves Marangoni, Benjamin D. Korman, Jun Wei, Tammara A. Wood, Lauren V. Grham, Michael L. Whithfield, Philipp E. Scherrr, Warren G. Tourtellott, John Varga

Arthritis & Rheumatology (Wiley) USA, 27 March 2014

Rheumatology

Key words: Myofibroblasts, systemic sclerosis, growth factor β, canonical adipogenic markers

Organism: Mouse

Tissue: Skin

Pathological State: Fibrosis

1142
In vivo real-time fluorescence visualization and brain-targeting mechanisms of lipid nanocarriers with different fatty ester:oil ratios

Chih-Jen Wen, Tzu-Chen Yen, Saleh A Al-Suwayeh, Hui-Wen Chang, Jia-You Fang

Future Medicine (FSG) Taiwan, Saudi Arabia, 27 March 2014

Nanomedicine

Key words: Lipid nanocarriers, cetyl palmitate, squalene, sulforhodamine B

Organism: Rat

Tissue: Brain

1143
RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis

Marion Lapierre, Sandrine Bonnet, Caroline Bascoul-Mollevi, Imade Ait-Arsa, Stéphan Jalaguier, Maguy Del Rio, Michela Plateroti, Paul Roepman, Marc Ychou, Julie Pannequin, Frédéric Hollande, Malcolm Parker, and Vincent Cavailles1

Journal of Clinical Investigation (American Society for Clinical Investigation) France, The Netherlands, UK, 25 March 2014

Oncology

Organism: Human

Tissue: Colon

Pathological State: Cancer

1144
Ambivalent role of pFAK-Y397 in serous ovarian cancer-a study of the OVCAD consortium

Stefanie Aust, Katharina Auer, Anna Bachmayr-Heyda, Carsten Denkert, Jalid Sehouli, Ioana Braicu, Sven Mahner, Sandrina Lambrechts, Ignace Vergote, Christoph Grimm, Reinhard Horvat, Dan Cacsire Castillo-Tong, Robert Zeillinger Dietmar Pils

Molecular Cancer (Springer) Austria, Germany, Belgium, 21 March 2014

Oncology

Key words: FAK, pFAK, molecular subclassification, immunohistochemistry, prognosis, ovarian cancer

Organism: Human

Tissue: Ovaries

Pathological State: Cancer

1145
Protection against Dengue Virus Infection in Mice by Administration of Antibodies against Modified Nonstructural Protein 1

Shu-Wen Wan, Yi-Tien Lu, Chia-Hui Huang, Chiou-Feng Lin, Robert Anderson, Hsiao-Sheng Liu, Trai-Ming Yeh, Yu-Ting Yen, Betty A. Wu-Hsieh , Yee-Shin Lin

PLoS One (PLOS) Taiwan, Canada, 21 March 2014

Virology

Key words: Hemorrhage, endothelial cells, platelets, complement system, dengue fever, hematoxylin staining, inoculation, macrophages

Organism: Mouse

Tissue: Skin

Pathological State: Dengue Virus Infection

1146
Lamin B2 prevents chromosome instability by ensuring proper mitotic chromosome segregation

T Kuga, H Nie, T Kazami, M Satoh, K Matsushita, F Nomura, K Maeshima, Y Nakayama and T Tomonaga

Oncogenesis (Nature) Japan, 17 March 2014

Oncology

Key words: Chromosome segregation, Colorectal cancer, Mitotic spindle

Organism: Human

Tissue: Colon

Pathological State: Cancer

1147
Hedgehog Pathway Inhibition in Chondrosarcoma Using the Smoothened Inhibitor IPI-926 Directly Inhibits Sarcoma Cell Growth

Veronica T. Campbell, Puviindran Nadesan, S. Amanda Ali, Chang Ye Yale Wang, Heather Whetstone, Raymond Poon, Qingxia Wei, John Keilty, Jennifer Proctor, Lauren W. Wang, Suneel S. Apte, Karen McGovern, Benjamin A. Alman, Jay S. Wunder

Molecular Cancer Therapeutics (AACR Publications) USA, Canada, 14 March 2014

Oncology

Key words: Hedgehog (Hh) pathway, Chondrosarcoma, transmembrane receptor Patched

Organism: Mouse

Tissue: Xenograft Tumor, Cartilage

Pathological State: Cancer

1148
Blockade of Fas Signaling in Breast Cancer Cells Suppresses Tumor Growth and Metastasis via Disruption of Fas Signaling-initiated Cancer-related Inflammation

Qiuyan Liu, Qinchun Tan, Yuanyuan Zheng, Kun Chen, Cheng Qia, Nan Li, Qingqing Wang, Xuetao Cao

Journal of Biological Chemistry (American Society for Biochemistry and Molecular Biology) China, 13 March 2014

Oncology

Key words: Breast Cancer, fas inflammation, prostaglandins, tumor metastases IL-6 MDSC PGE2

Organism: Mouse

Tissue: Breast

Pathological State: Cancer

1149
Interleukin-1β Attenuates Myofibroblast Formation and Extracellular Matrix Production in Dermal and Lung Fibroblasts Exposed to Transforming Growth Factor-β1

Masum M. Mia, Ruud A. Bank, Miriam Boersema

PLoS One (PLOS) The Netherlands, 12 March 2014

Cell Biology

Key words: Fibroblasts, collagens, gene expression, fibrosis, immunofluorescence staining, tissue repair, cytokines, lungs

Organism: Human

Cell Line: HDFa and HLFa cells

1150
5th International meeting on angiogenesis

Angiogenesis (Springer) The Netherlands, 08 March 2014

Regenerative Medicine

1151
Impact of the Smoothened Inhibitor, IPI-926, on Smoothened Ciliary Localization and Hedgehog Pathway Activity

Marisa O. Peluso, Veronica T. Campbell, Joseph A. Harari, Thomas T. Tibbitts, Jennifer L. Proctor, Nigel Whitebread, James M. Conley, Kerry F. White, Jeffery L. Kutok, Margaret A. Read, Karen McGovern, Kerrie L. Faia

PLoS One (PLOS) USA, 07 March 2014

Oncology

Key words: Hedgehog signaling NIH 3T3 cells, cancer treatment, cell binding assay, cilia, gene expression, luciferase, cell staining

Organism: Human

Cell Line: HEPM and NIH-3T3 cells

1152
Excessive activation of the alternative complement pathway in autosomal dominant polycystic kidney disease

Z. Su, X. Wang, Gao,Y.Liu, C.Pan, H. Hu, R. P. Beyer, M. Shi, J. Zhou, J. Zhang, A. L. Serra, R. P. Wüthrich, C. Mei

Journal of Internal Medicine (Wiley) China, Switzerland, USA, 02 March 2014

Nephrology

Key words: Autosomal dominant polycystic kidney disease, complement, complement inhibitor, glycoproteomics, urine

Organism: Rat

Tissue: Kidney

Pathological State: Polycystic Kidney Disease

1153
AB0206 Altered Expression of Angiopoietins and Tie-2 in Ischemic Lesions of UCD-206 Chickens, an Animal Model for Systemic Sclerosis

S. Allipour Birgani, H. Dietrich, R. Sgonc

Annals of the Rheumatic Diseases (BMJ Journals) Austria, 01 March 2014

Rheumatology

Key words: Systemic sclerosis, vascular endothelial growth factor , endothelial cells

1154
Multimodality imaging to assess immediate response to irreversible electroporation in a rat liver tumor model

Yue Zhang, Sarah B. White, Jodi R. Nicolai, Zhuoli Zhang, Derek L. West, Dong-hyun Kim, A. Lee Goodwin, Frank H. Miller, Reed A. Omary, Andrew C. Larson

Radiology (Radiological Society of North America) USA, 18 February 2014

Oncology

Organism: Rat

Tissue: Liver

Pathological State: Cancer

1155
Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma

Winnie W. Lo, Jay S. Wunder, Brendan C. Dickson, Veronica Campbell, Karen McGovern , Benjamin A. Alman, Irene L. Andrulis

Cancer (Wiley) Canada, USA, 15 February 2014

Oncology

Key words: Osteosarcoma, hedgehog signaling, ligand-dependent,IPI-926, microenvironment

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

1156
Iron deficiency alters megakaryopoiesis and platelet phenotype independent of thrombopoietin

Rayko Evstatiev, Adam Bukaty, Kristine Jimenez, Stefanie Kulnigg-Dabsch, Lidia Surman, Werner Schmid, Robert Eferl, Kathrin Lippert, Barbara Scheiber-Mojdehkar, Hans Michael Kvasnicka, Vineeta Khare, Christoph Gasch

American Journal of Hematology (Wiley) Austria, Germany, 14 February 2014

Hematology

Key words: Iron deficiency

Organism: Rat

Tissue: Bone Marrow

1157
NKG2D+ IFN-γ+ CD8+ T Cells Are Responsible for Palladium Allergy

Mitsuko Kawano, Masafumi Nakayama, Yusuke Aoshima, Kyohei Nakamura, Mizuho Ono, Tadashi Nishiya, Syou Nakamura, Yuri Takeda, Akira Dobashi, Akiko Takahashi, Misato Endo, Akiyo Ito, Kyosuke Ueda, Naoki Sato, Shigehito Higuchi, Takeru Kondo, Suguru Hashimoto, Masamichi Watanabe, Makoto Watanabe, Tetsu Takahashi,Keiichi Sasaki, Masanori Nakamura, Takehiko Sasazuki, Takayuki Narushima, Ryuji Suzuki, Kouetsu Ogasawara

PLoS One (PLOS) Japan, 12 February 2014

Allergy Research

Key words: T cells, cytotoxic T cells, allergies, mouse models, adoptive transfer, lymphocytes, allergy immunotherapy, lymph nodes

Organism: Mouse

Tissue: Lymphoid Tissue

Pathological State: Allergy

1158
Successful treatment of adult onset Langerhans cell histiocytosis with bi-weekly administration of pegylated interferon-α

Sadanori Furudate, Taku Fujimura, Yumi Kambayashi, Mitsuko Kawano, Kouetsu Ogasawara, Akira Tsukada, Erika Tamabuchi, Takahiro Haga, Akira Hashimoto and Setsuya Aiba

Acta Dermato Venereologica (Ingentaconnect) Japan, 04 February 2014

Dermatology

Organism: Human

Tissue: Skin

Pathological State: Histiocytosis

1159
Serum Level of IL-10 Is Increased in Patients with Endometriosis, and IL-10 Promotes the Growth of Lesions in a Murine Model

Jau-Ling Suen, Yu Chang, Pu-Rong Chiu, Tsung-Hua Hsieh, Edward Hsi, Yu-Chieh Chen, Yu-Fang Chen, Eing-Mei Tsai

The American Journal of Pathology (American Society for Investigative Pathology) Taiwan, 01 February 2014

Pathology

Key words: Immune dysregulation, anti-inflammatory cytokine IL-10, Monocyte-derived dendritic cells

Organism: Mouse

Tissue: Uterus

Pathological State: Endometriosis

1160
Metformin anti-tumor effect via disruption of the MID1 translational regulator complex and AR downregulation in prostate cancer cells

Ummuhan Demir, Andrea Koehler, Rainer Schneider, Susann Schweiger, Helmut Klocker

BMC Cancer (Springer) Austria, Germany, 31 January 2014

Oncology

Key words: Metformin, Androgen receptor, MID1-α4/PP2A protein complex, AMPK ,Translational regulation, CoIP

Organism: Human

Cell Line: LNCaP, Du-145, VCaP and PC-3 cells

1161
Role of oncogenic K-Ras in cancer stem cell activation by aberrant Wnt/β-catenin signaling

BS Moon, WJ Jeong, J Park, TI Kim, DS Min, KY Choi

Journal of the National Cancer Institute (Oxford University Press) South Korea, 31 January 2014

Oncology

Key words: signal transduction, mutation, cd44 antigens, transplantation, heterologous, mice, neoplasms, k-ras oncogene, homing-associated cell adhesion molecule, cancer stem cells

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

1162
Die prognostische Bedeutung von Tumor-infiltrierenden CD8+Zellen: eine detaillierte Analyse in Hinblick auf Tumor-Debulking und Zell-Proliferation

S Aust, A Bachmayr-Heyda, S Polterauer, D Pils, DC Castillo-Tong, OVCAD Consortium

Geburtshilfe und Frauenheilkunde (Thieme) Austria, 30 January 2014

Immunology

1163
The role of the organic anion transporting polypeptide OATP4A1 in immunactivation in colorectal cancer and inflammatory colon disease.

Christoph Alexander Ausch, Simone Zotter, Maidah Scheikh, Heike Bauer, Marina Mollik, Erika Bajna, Christian Sebesta, Angelika Reiner, Theresia Thalhammer and Veronika Buxhofer-Ausch

Journal of Clinical Oncology (American Society of Clinical Oncology) , 20 January 2014

Oncology

Key words: Prostaglandins, cyclic nucleotides, second messenger proteins, tumor cells growth

1164
A dual role for autophagy in a murine model of lung cancer

Shuan Rao, Luigi Tortola, Thomas Perlot, Gerald Wirnsberger, Maria Novatchkova, Roberto Nitsch, Peter Sykacek, Lukas Frank, Daniel Schramek, Vukoslav Komnenovic, Verena Sigl, Karin Aumayr, Gerald Schmauss, Nicole Fellner, Stephan Handschuh, Martin Glösmann, Pawel Pasierbek, Michaela Schlederer, Guenter P. Resch, Yuting Ma, Heng Yang, Helmuth Popper, Lukas Kenner, Guido Kroemer and Josef M. Penninger

Nature Communications (Nature) Austria, France, 20 January 2014

Oncology

Key words: Autophagy, Lung cancer, Oncogenesis

Organism: Mouse

Tissue: Lung

Pathological State: Cancer

1165
Glycogen Synthase Kinase 3β (GSK3β) Regulates Differentiation and Proliferation in Neural Stem Cells from the Rat Subventricular Zone 1

Martin H. Maurer, Jens O. Brömme, Robert E. Feldmann, Jr Anne Järve, Fatemeh Sabouri, Heinrich F. Bürgers, Dominik W. Schelshorn, Carola Krüger, Armin Schneider, Wolfgang Kuschinsky

Journal of Proteome Research (ACS Publications) Germany, 18 January 2014

Stem Cell Research

Key words: Neural stem cell, Neurosphere, Glycogen Synthase Kinase 3β, Two-dimensional gel electrophoresis, Rat, Subventricular zone

Organism: Rat

Tissue: Brain

1166
NF-E2-related factor 2 promotes compensatory liver hypertrophy after portal vein branch ligation in mice

Keiichi Shirasaki, Keiko Taguchi, Michiaki Unno, Hozumi Motohashi, Masayuki Yamamoto

Hepatology (Wiley) Japan, 17 January 2014

Hepathology

Key words: Hepatectomy, portal vein embolization, phosphoinositide 3-kinase, protein kinase B (PI3K/Akt) pathway

Organism: Mouse

Tissue: Liver

1167
Hepatic RIG-I Predicts Survival and Interferon-α Therapeutic Response in Hepatocellular Carcinoma

Jin Hou, Ye Zhou, Yuanyuan Zheng, Jia Fan, Weiping Zhou, Irene O.L. Ng, Huichuan Sun, Lunxiu Qin, Shuangjian Qiu, Joyce M.F. Lee, Chung-Mau Lo, Kwan Man, Yuan Yang, Yun Yang, Yingyun Yang, Qian Zhang, Xuhui Zhu, Nan Li, Zhengxin Wang, Guoshan Ding, Shi-Mei Zhuang, Limin Zheng, Xiaoling Luo, Yuan Xie, Anmin Liang, Zhugang Wang, Ming Zhang, Qiang Xia, Tingbo Liang, Yizhi Yu, Xuetao Cao

Cancer Cell (Cell Press) China, 13 January 2014

Oncology

Key words: Hepatocellular carcinoma, interferon-α, retinoic acid-inducible gene-I

Organism: Human

Tissue: Liver

Pathological State: Liver Hemangioma

1168
Diverse T-cell responses characterize the different manifestations of cutaneous graft-versus-host disease

Marie-Charlotte Brüggen, Irene Klein, Hildegard Greinix, Wolfgang Bauer, Zoya Kuzmina, Werner Rabitsch, Peter Kalhs, Peter Petzelbauer, Robert Knobler, Georg Stingl, Georg Stary

Blood (American Society of Hematology) Austria, 09 January 2014

Transplantation Medicine

Key words: Distinct T-cell patterns characterize the acute and chronic forms of cutaneous GVHD, increased TSLP expression is an indicator of acute cutaneous GVHD development.

Organism: Human

Tissue: Skin

Pathological State: Cutaneous graft-versus-host disease

1169
Resveratrol enhances the chemopreventive effect of celecoxib in chemically induced breast cancer in rats

Terézia Kisková, Rastislav Jendzelovsky, Erdenetsetsek Rentsen, Alexandra Maier-Salamon, Natalia Kokosova, Zuzana Papcova,Jaromır Mikes, Peter Orendas, Bianka Bojkova, Peter Kubatka, Martin Svoboda, Karol Kajo, Peter Fedorocko, Walter Jager, Cem Ekmekcioglu, Monika Kassayova and Theresia Thalhammer

European Journal of Cancer Prevention (Wolters Kluwer) Austria, 01 January 2014

Oncology

Key words: celecoxib, chemically induced breast cancer, COX2, GDF15, MCF-7 cells, oxidative stress, resveratrol

Organism: Rat

Tissue: Breast

Pathological State: Cancer

1170
Macrophage Quantification in Different Breast Tumor Compartments.

Haisan, Anca, Petreus, T., Jitaru, Daniela, Danciu, M., Carasevici, E.

Jurnalul de Chirurgie (search.ebscohost.com) Romania, 01 January 2014

Oncology

1171
Lymph node status assessed through the log odds ratio–a better tool in the prognosis of colorectal cancer relapse

ST Makkai-Popa, S Luncă, E Târcoveanu, E Carasevici, G Dimofte

Romanian Journal of Morphology and Embryology () Romania, 01 January 2014

Oncology

Key words: disease-free interval, lymph node ratio, log odds ratio.

1172
HISTOQUEST–MODALITY OF MICROANATOMICAL ANALYSIS OF THE IMMUNOHISTOCHEMICAL COLORATION IN BREAST CANCER AND DATA …

Vrânceanu, Anca, Tărniceriu, Claudia Cristina, Makkai, S., Carasevici, E.

(search.ebscohost.com) Romania, 01 January 2014

Oncology

1173
Role of endocytic uptake in transfection efficiency of solid lipid nanoparticles-based nonviral vectors

Aritz Perez Ruiz de Garibay, María Ángeles Solinís Aspiazu, Alicia Rodríguez Gascón, Haleh Ganjian, Renate Fuchs

Journal of Gene Medicine (Wiley) Spain, Austria, 27 December 2013

Nanomedicine

Key words: Endocytosis, lysosome, nonviral vector, solid lipid nanoparticles, transfection

Organism: Human

Cell Line: HeLa cells

1174
Ginsenoside Rg3 Up-regulates the Expression of Vascular Endothelial Growth Factor in Human Dermal Papilla Cells and Mouse Hair Follicles

Dae Hyun Shin, Youn Jeong Cha, Kyeong Eun Yang, Ik-Soon Jang, Chang-Gue Son, Bo Hyeon Kim, Jung Min Kim

Phytotherapy Research (Wiley) South Korea, 26 December 2013

Dermatology

Key words: Rg3, hair growth, DP cell, gene expression profiles, VEGF, stemness marker

Organism: Human

Cell Line: Dermal Papilla cells

1175
Application of quinidine on rat sciatic nerve decreases the amplitude and increases the latency of evoked responses

Kuang-I Cheng, I-Ling Lin, Lin-Li Chang, I-Ming Jou, Chung-Sheng Lai, Jhi-Joung Wang, Hung-Chen Wang, Aij-Lie Kwan

Journal of Anesthesia (Springer) Taiwan, 15 December 2013

Anesthesiology

Key words: Sciatic nerve, lidocaine, sciatic nerve fiber, contralateral hind limb, rat sciatic nerve, quinidine concentration, sodium channel, ranvier node, myelinated nerve fiber, local anesthetic, nerve conduction, peripheral nerve, neuropathic pain, conduction velocity

Organism: Rat

Tissue: Brain

1176
Autophagy suppresses tumorigenesis of hepatitis B virus-associated hepatocellular carcinoma through degradation of microRNA-224

Sheng-Hui Lan, Shan-Ying Wu, Roberto Zuchini, Xi-Zhang Lin, Ih-Jen Su, Ting-Fen Tsai, Yen-Ju Lin, Cheng-Tao Wu and Hsiao-Sheng Liu

Hepatology (Wiley) Taiwan, 13 December 2013

Oncology

Key words: microRNA-224, miR‐224 antagonist, autophagosome fraction, autophagy‐related genes, chloroquine, double distilled water, digoxigenin, hepatitis B virus, hepatitis B virus X protein, hepatocellular carcinoma, hepatitis C virus

Organism: Human

Tissue: Liver

Pathological State: Cancer

1177
Overexpression of FGF9 in colon cancer cells is mediated by hypoxia-induced translational activation

Tsung-Ming Chen, Yu-Heng Shih, Joseph T. Tseng, Ming-Chih Lai, Chih-Hao Wu, Yi-Han Li, Shaw-Jenq Tsai, H. Sunny Sun

Nucleic Acids Research (Oxford University Press) Taiwan, 10 December 2013

Oncology

Key words: Human fibroblast growth factor 9 , hypoxia, colon cancer cells

Organism: Human

Tissue: Colon

Pathological State: Cancer

1178
Localized Hyperthermia with Iron Oxide–Doped Yttrium Microparticles: Steps toward Image-Guided Thermoradiotherapy in Liver Cancer

Andrew C. Gordon, Robert J. Lewandowski, Riad Salem,, Delbert E. Day, Reed A. Omary, Andrew C. Larson

Journal of Vascular and Interventional Radiology (Elsevier) USA, 06 December 2013

Oncology

Key words: Hepatocellular carcinoma, normal hepatic parenchyma, alternating magnetic field

Organism: Rat

Tissue: Liver

Pathological State: Cancer

1179
MAR-mediated integration of plasmid vectors for in vivo gene transfer and regulation

Stefania Puttini, Ruthger W van Zwieten, Damien Saugy, Malgorzata Lekka, Florence Hogger, Deborah Ley, Andrzej J Kulik, Nicolas Mermod

BMC Molecular Biology (Springer) Switzerland, Poland, 02 December 2013

Genetics

Key words: Inducible expression, non-viral vectors, MAR elements, erythropoietin, utrophin, gene therapy

Organism: Mouse

Tissue: Muscle

1180
Langerhans cell maturation is accompanied by induction of N-cadherin and the transcriptional regulators of epithelial–mesenchymal transition ZEB1/2

Sabine Konradi, Nighat Yasmin1, Denise Haslwanter, Michele Weber, Bernhard Gesslbauer, Michael Sixt, Herbert Strobl

European Journal of Immunology (Wiley) Austria, 02 December 2013

Immunology

Key words: Cell migration, dendritic cells, epithelial-to-mesenchymal transition, langerhans cells, maturation

Organism: Human

Cell Line: Langerhans cells

1181
Transdifferentiation of Adipose-Derived Stem Cells into Keratinocyte-Like Cells: Engineering a Stratified Epidermis

Claudia Chavez-Munoz, Khang T. Nguyen,Wei Xu, Seok-Jong Hong,Thomas A. Mustoe, Robert D. Galiano

PLoS One (PLOS) USA, 02 December 2013

Stem Cell Research

Key words: Keratinocytes, cell staining, transdifferentiation, cell differentiation, mesenchymal stem cells, DAPI staining, antibiotics, fibroblasts

Organism: Human

Cell Line: Adipose-Derived Stem Cells

1182
Targeting SOD1 reduces experimental non–small-cell lung cancer

Andrea Glasauer, Laura A. Sena, Lauren P. Diebold, Andrew P. Mazar, and Navdeep S. Chandel

Journal of Clinical Investigation (American Society for Clinical Investigation) USA, 02 December 2013

Oncology

Organism: Mouse

Tissue: Lung

Pathological State: Cancer

1183
A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog

Astrid Hagelkruys, Sabine Lagger, Julia Krahmer, Alexandra Leopoldi, Matthias Artaker, Oliver Pusch, Jürgen Zezua, Simon Weissmann, Yunli Xie, Christian Schöfer, Michaela Schlederer, Gerald Brosch, Patrick Matthias, Jim Selfridge, Hans Lassmann, Jürgen A. Knoblich, Christian Seiser

Development (The Company of Biologists) Austria, Switzerland, UK, 19 November 2013

Neuroscience

Key words: Histone deacetylases, neural cells, histone acetyltransferases, central nervous system

Organism: Mouse

Tissue: Brain

1184
Developmental and oncogenic radiation effects on neural stem cells and their differentiating progeny in mouse cerebellum

Mirella Tanori, Emanuela Pasquali, Simona Leonardi, Arianna Casciati, Paola Giardullo, Ilaria De Stefano, Mariateresa Mancuso, Anna Saran, Simonetta Pazzaglia

Stem Cells (Wiley) Italy, 15 November 2013

Stem Cell Research

Key words: Ptc1+/- mice, apoptosis, DNA repair, p21, medulloblastoma, carcinogenesis, neural stem cells, progenitor cells

Organism: Mouse

Tissue: Brain

1185
Epidermal Growth Factor Receptor Targeted Nuclear Delivery and High-Resolution Whole Cell X-ray Imaging of Fe3O4@TiO2 Nanoparticles in Cancer Cells

Ye Yuan, Si Chen, Tatjana Paunesku, Sophie Charlotte Gleber, William C. Liu, Caroline B. Doty, Rachel Mak, Junjing Deng, Qiaoling Jin, Barry Lai, Keith Brister, Claus Flachenecker, Chris Jacobsen, Stefan Vogt, Gayle E. Woloschak

ACS NANO (ACS Publications) USA, 12 November 2013

Medical Imaging

Key words: Nanoparticles, titanium dioxide, photoactivation, X-ray fluorescence microscopy, epidermal growth factor receptor

Organism: Human

Cell Line: HeLa cells

1186
Cardiac magnetic resonance postcontrast T1 time is associated with outcome in patients with heart failure and preserved ejection fraction

Mascherbauer J, Marzluf BA, Tufaro C, Pfaffenberger S, Graf A, Wexberg P, Panzenböck A, Jakowitsch J, Bangert C, Laimer D, Schreiber C, Karakus G, Hülsmann M, Pacher R, Lang IM, Maurer G, Bonderman D.

Circulation:Cardiovascular Imaging (AHA Journals) Austria, Turkey, 06 November 2013

Cardiology

Key words: Hypertension, pulmonary, magnetic resonance imaging, prognosis

Organism: Human

Tissue: Heart

Pathological State: Heart Failure

1187
Alcohol Exacerbates LPS-Induced Fibrosis in Subclinical Acute Pancreatitis

Haitao Gu, Franco Fortunato, Frank Bergmann, Markus W. Büchler, David C. Whitcomb, Jens Werner

American journal of Pathology (Elsevier) Germany, 01 November 2013

Gastroenterology

Key words: Pancreatic acinar cells, alcoholic acute pancreatitis, growth factor-β of acinar cells, pancreatic fibrosis

Organism: Rat

Tissue: Pancreas

Pathological State: Cancer

1188
Hypercapnia Impairs Lung Neutrophil Function and Increases Mortality in Murine Pseudomonas Pneumonia

Khalilah L. Gates , Heather A. Howell , Aisha Nair , Christine U. Vohwinkel , Lynn C. Welch , Greg J. Beitel , Alan R. Hauser , Jacob I. Sznajder , and Peter H. S. Sporn

American Journal of Respiratory Cell and Molecular Biology (ATS Journals) USA, 01 November 2013

Pulmonology

Key words: arbon dioxide, pulmonary infection, reactive oxygen species, phagocytosis, inflammation

Organism: Mouse

Tissue: Lung

Pathological State: Pseudomonas Pneumonia

1189
Corelation of Lymphocytic Infiltrates with the Prognosis of Recurrent Colo-Rectal Cancer

ST Makkai-Popa, S Luncã, G Dimofte, A Vrânceanu, D. Franciug, I Ivanov, F Zugun, E Târcoveanu, E Carasevici

Chirurgia (revistachirurgia) Romania, 01 November 2013

Oncology

Key words: relapse prognosis, colo-rectal cancer, quantitative assessment of immunohistochemical staining, digital image analysis, cytotoxic T cells

Organism: Human

Tissue: Colon

Pathological State: Cancer

1190
Targeting of sodium–glucose cotransporters with phlorizin inhibits polycystic kidney disease progression in Han: SPRD rats

X Wang, S Zhang, Y Liu, D Spichtig, S Kapoor, H koepsell, N Mohebbi, S Sergerer, AL Serra, D Rodriguez, O Devuyst, C Mei, RP Wüthrich

Kidney international (Elsevier) Switzerland, China, Germany, 01 November 2013

Nephrology

Key words: polycystic, phlorizin, rat, sodium–glucose cotransport

Organism: Rat

Tissue: Kidney

Pathological State: Polycystic kidney disease

1191
Renal Heparan Sulfate Proteoglycans Modulate Fibroblast Growth Factor 2 Signaling in Experimental Chronic Transplant Dysfunction

Kirankumar Katta, Miriam Boersema, Saritha Adepu, Heleen Rienstra, Johanna W.A.M. Celie, Rik Mencke, Grietje Molema, Harry van Goor, Jo H.M. Berden, Gerjan Navis, Jan-Luuk Hillebrands, Jacob van den Born

The American Journal of Pathology (Elsevier) The Netherlands, 01 November 2013

Transplantation Medicine

Key words: Renal transplantation, proteoglycans, chronic transplant dysfunction, laser-microdissected glomeruli

Organism: Rat

Tissue: Kidney

Pathological State: Chronic Transplant Dysfunction

1192
AKIP1, a cardiac hypertrophy induced protein that stimulates cardiomyocyte growth via the Akt pathway

H Yu, W Tigchelaar, B Lu, WH van Gilst, RA De Boer, B Daan Westenbrink, HHW Sillje

International Journal of Molecular Sciences (MDPI) The Netherlands, China, 28 October 2013

Cardiology

Key words: cardiac hypertrophy, AKIP1, Akt, kinase, remodeling

Organism: Rat

Cell Line: Neonatal rat ventricular cardiomyocytes

1193
Regulation of the calcium-sensing receptor expression by 1,25-dihydroxyvitamin D3, interleukin-6, and tumor necrosis factor alpha in colon cancer cells

Irfete S. Fetahu, Doris M. Hummel, Teresa Manhardt, Abhishek Aggarwal, Sabina Baumgartner-Parzer, Eniko Kállay

The Journal of Steroid Biochemistry and Molecular Biology (Elsevier) Austria, 28 October 2013

Oncology

Key words: Calcium-sensing receptor, colon cancer, tumor necrosis factor alpha, interleukin, 1,25-dihydroxyvitamin D3, Inflammation

Organism: Human

Cell Line: Caco-2 Cells

1194
Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie

Oncology research and treatment (Karger) Austria, 22 October 2013

Oncology

1195
Effects on tumor development and metastatic dissemination by the NKG2D lymphocyte receptor expressed on cancer cells

A El-Gazzar, X Cai, R S Reeves, Z Dai, A Caballero-Benitez, D L McDonald, J Vazquez, T A Gooley, G E Sale, T Spies and V Groh

Oncogene (Nature) USA, 21 October 2013

Oncology

Key words: Breast cancer, Metastasis, Oncogene proteins, Oncogenesis

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

1196
Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation

Marco Peviani, Eleonora Salvaneschi, Leonardo Bontempi, Alessandro Petese, Antonio Manzo, Daniela Rossi, Mario Salmona, Simona Collina, Paolo Bigini, Daniela Curti

Neurobiology of Disease (Elsevier) Italy, 16 October 2013

Neuroscience

Key words: Sigma-1 receptor, motor neurons, BDNF, reactive gliosis, neurodegeneration, obbler

Organism: Mouse

Tissue: Spinal Cord

Pathological State: Motor Neuron Disease

1197
Overexpression of the Transcriptional Repressor Complex BCL-6/BCoR Leads to Nuclear Aggregates Distinct from Classical Aggresomes

Elisabeth Buchberger, Miriam El Harchi, Dietmar Payrhuber, Anna Zommer, Dominic Schauer, Ingrid Simonitsch-Klupp, Martin Bilban, Christine Brostjan

PLoS One (PLOS) Austria, 11 October 2013

Cell Biology

Key words: Transfection, chaperone proteins, heat shock response, plasmid construction, cell staining, immunostaining, nuclear bodies, protein structure

Organism: Human

Cell Line: Primary Ecs

1198
Suberoylanilide Hydroxamic Acid, an Inhibitor of Histone Deacetylase, Enhances Radiosensitivity and Suppresses Lung Metastasis in Breast Cancer In Vitro and In Vivo

Hui-Wen Chiu, Ya-Ling Yeh, Yi-Ching Wang, Wei-Jan Huang, Yi-An Chen, Yi-Shiou Chiou, Sheng-Yow Ho, Pinpin Lin, Ying-Jan Wang

PLoS One (PLOS) Taiwan, 10 October 2013

Oncology

Key words: Cancer treatment, autophagic cell death, breast cancer, DNA damage, apoptosis, metastasis, fluorescence microscopy, DNA repair

Organism: Mouse

Tissue: Breast

Pathological State: Cancer

1199
Necro-inflammatory response of pancreatic acinar cells in the pathogenesis of acute alcoholic pancreatitis

H Gu, J Werner, F Bergmann, DC Whitcomb, MW Büchler, F Fortunato

Cell Death & Disease (Nature) Germany, USA, 03 October 2013

Gastroenterology

Key words: Acute pancreatitis, Inflammation, Necroptosis

Organism: Rat, Human

Tissue: Pancreas

Pathological State: Acute alcoholic pancreatitis

1200
Characterization of T Cell Receptors of Th1 Cells Infiltrating Inflamed Skin of a Novel Murine Model of Palladium-Induced Metal Allergy

Hiroshi Kobayashi, Kenichi Kumagai, Takanori Eguchi, Hiroaki Shigematsu, Kazutaka Kitaura, Mitsuko Kawano, Tatsuya Horikawa, Satsuki Suzuki, Takaji Matsutani, Kouetsu Ogasawara, Yoshiki Hamada, Ryuji Suzuki

PLoS One (PLOS) Japan, 03 October 2013

Allergy Research

Key words: T cells, allergies, T cell receptors, polymerase chain reaction, cytokines, inflammation, chemokines, sequence analysis

Organism: Mouse

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