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Event

29 Aug, 2025

Meet Us at the Annual Meeting of the Australian and New Zealand Society for Immunology (ASI)

TissueGnostics will be at the ASI 2025 meeting, 1–5 December in Perth, Australia. Join one of the region’s largest immunology events and meet our team to discuss your imaging needs.

tissue slide scanners

image analysis

immunology

collaboration

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Application Note

12 Mar, 2025

Investigating T-Cell Communities in Immune Tissues with StrataQuest 8

Multiplex fluorescence imaging of tonsil tissue analyzed in StrataQuest to quantify and map T-cell subsets within and around germinal centers.

image analysis

spatial analysis

multiplex IF

immunology

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Webinar

13 Nov, 2024

From Slide to Insight: High-Throughput Tissue Cytometry with TissueGnostics and CrestOptics

TissueGnostics and CrestOptics hosted a webinar demonstrating how TissueFAXS Confocal Cytometers integrate high-throughput imaging, modular workflows, and real-world applications in biomedical research.

image analysis

high-throughput imaging

collaboration

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White Paper

30 Oct, 2024

Improving the Efficacy of Immunotherapy in Lung Cancer Through Novel Target Discoveries

Researchers from Soochow University investigated the B7-H4/USP2a axis in lung cancer using TissueFAXS Spectra for TMA imaging and StrataQuest for protein expression analysis.

image analysis

tumor microenvironment

oncology

biomarker discovery

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Application Note

14 Oct, 2024

Quantitative Analysis of Cultured Cells: High-End Solution for Ready-To-Publish Data

A case study using StrataQuest image analysis on IF-processed cultured cells. The workflow automated cell identification, nuclei and cytoplasm counting, and marker intensity quantification.

intracellular analysis

image analysis

cell quantification

cell culture

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Application Note

11 Sep, 2024

A Glimpse into StrataQuest 8: Spatial Analysis in Colorectal Cancer

The newest StrataQuest supports in-depth neighborhood analysis with exportable data for statistics. It includes manifold learning (t-SNE, UMAP, SONG), violin plots, 3D diagrams, and other tools that give full control of data.

image analysis

spatial analysis

oncology

immunophenotyping

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Blog Post

08 Nov, 2023

Does Precision Medicine Represent a Healthcare Revolution?

Precision medicine is reshaping healthcare by tailoring treatment to each patient’s molecular profile. With tools like tissue cytometry, TissueFAXS, and StrataQuest, researchers can uncover genetic drivers, track therapy response, and advance personalized care.

image analysis

oncology

genomics

precision medicine

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Blog Post

23 Oct, 2023

Understanding the Challenges of Immunofluorescence Image Analysis

Immunofluorescence image analysis is a powerful tool for profiling tumor microenvironments, but multiplexing and complex datasets bring major challenges. With tools like TissueFAXS SPECTRA and StrataQuest, researchers can optimize workflows and improve accuracy.

image analysis

tumor microenvironment

multiplex IF

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News

16 Oct, 2023

Deep Learning for Improved Nuclei Segmentation in Microscopic Images

Dr. Amirreza Mahbod presents how deep learning enhances nuclei segmentation and tackles challenges in histological image analysis.

single-cell analysis

image analysis

AI-powered analysis

expert insights

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Application Note

14 Feb, 2023

Case Study: Analysis of FISH Using Tissue Cytometry

The IF Dots App in StrataQuest streamlines automated analysis of FISH stainings by detecting nuclei and quantifying dots per cell. This case study shows how the workflow enables accurate, exportable data for genetics research and clinical applications.

image analysis

FISH analysis

digital pathology

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Blog Post

18 Jan, 2023

Understanding the Different Types of FISH Evaluations

FISH is a powerful imaging-based technique for detecting DNA and RNA sequences directly in cells and tissues. This post explores the advantages of FISH, its complementary methods like CISH and RNAscope, and how TG solutions streamline automated FISH analysis.

image analysis

FISH analysis

digital pathology

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Blog Post

28 Nov, 2022

How FISH Image Analysis Factors into Next-Gen Digital Pathology

How does FISH image analysis advance digital pathology? Learn how whole-slide imaging and AI-powered algorithms enable fast, accurate detection of chromosomal abnormalities, streamline workflows, and open new possibilities for precision medicine.

image analysis

FISH analysis

precision medicine

digital pathology

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Blog Post

19 Oct, 2022

How Deep Learning is Used for Cell Counting

Deep learning is transforming cell counting by enabling precise nuclei segmentation, even in dense tissue microenvironments. Learn how TissueGnostics applies deep neural networks (DNNs) to automate and improve accuracy in tissue cytometry workflows.

image analysis

cell quantification

AI-powered analysis

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Blog Post

12 Oct, 2022

How Cell Counting Algorithms Work

Cell counting is central to biomedical research, but accuracy depends on advanced algorithms. This blog explores manual vs automated methods, and how TissueGnostics’ AI-driven cell counting algorithms enable reliable, high-throughput image-based analysis.

image analysis

cell quantification

AI-powered analysis

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Webinar

12 Oct, 2022

Quantitative Image-based Cytometry: Focus on the Foci!

Prof. Nicolas C. Hoch, University of Sao Paulo, is presenting his research on signaling and repair of DNA damage. He and his group are utilizing the power of TissueFAXS i PLUS slide scanning and the high-end image analysis solution, StrataQuest, for their research.

fluorescence

single-cell analysis

image analysis

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Webinar

27 Jun, 2022

Exploring the World of Multiplexing IF in Human Immune System Studies, ELMI 2022

Dr. Thomas Diefenbach, The Ragon Institute Boston, presents various approaches for multiplexing IF, utilizing the power of TissueFAXS high-throughput automated slide scanning and StrataQuest powered high-end image analysis.

image analysis

high-throughput imaging

multiplex IF

immunology

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Blog Post

08 Jun, 2022

How to Carry Out Complex Characterization of the Tissue Microenvironment

Characterizing the tissue microenvironment reveals how cells and structures interact in health and disease. This blog highlights its role in cancer research and how TissueGnostics solutions enable advanced imaging and quantitative analysis.

tissue slide scanners

image analysis

tumor microenvironment

oncology

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Interview

11 May, 2022

Disrupted B and T Cell Dynamics in COVID-19 Lymph Nodes Revealed by Tissue Cytometry

Dr. Thomas Diefenbach and colleagues at the Ragon Institute analyzed B and T cell populations in COVID-19 patient lymph nodes using TissueFAXS and StrataQuest. Their microscopy and image analysis revealed disrupted germinal centers and impaired humoral immunity.

single-cell analysis

image analysis

immunology

infectious diseases

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About Us

TissueGnostics provides advanced solutions for whole-slide imaging and image analysis in biological and clinical research. Our products help researchers to scan and analyze complex tissue samples, enabling more detailed insights into tissue structure, cellular interactions, and spatial cell landscape.

 

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