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Customer Publications (A total of 1249 papers published)

Epicutaneously applied Der p 2 induces a strong TH2-biased antibody response in C57BL/6 mice, independent of functional TLR4

C. Stremnitzer, K. Manzano-Szalai, P. Starkl, A. Willensdorfer, S. Schrom, J. Singer, U. Reichart, S. Akira, E. Jensen-Jarolim

Allergy (Wiley) Austria, 16 April 2014


Key words:Allergic dermatitis, Der p 2, house dust mite, LPS, TLR4

Direct comparison of the dynamics of IL-25- and ‘allergen’-induced airways inflammation, remodelling and hypersensitivity in a murine asthma model

X. J. Yao, K. W. Huang, Y. Li, Q. Zhang, J. J. Wang, W. Wang, J. Liu, Z. Lv, Y. Q. An, Y. Z. Ding, C. J. Corrigan, W. Wang, Y. C. Sun, S. Ying

Clinical and Experimental Allergy (Wiley) China, UK, 16 April 2014


Key words:Asthma, IL-25, IL-25 receptor, murine model, pathogenesis, remodelling

Poly(lactide-co-glycolide) microspheres for MRI-monitored transcatheter delivery of sorafenib to liver tumors

Jeane Chen, Alexander Y. Sheu, Weiguo Li, Zhuoli Zhang, c, Dong-Hyun Kim, Robert J. Lewandowski, Reed A. Omary, Lonnie D. Shea, Andrew C. Larson

Journal of Controlled Release (Elsevier) USA, 13 April 2014


Key words:Sorafenib, hepatocellular carcinoma, magnetic resonance imaging, poly(lactide-co-glycolide)

Abstract 1662: Towards automated analysis of prostate inflammatory state: Assessing density and distance of infiltrating T-cells (CD3+) to glandular structures in prostate biopsies by a new software

Radu Rogojanu, Bogdan Boghiu, Georg Schaefer, Theresia Thalhammer, Georg Steiner, Rupert Ecker, Bettina Schlick, Thomas Szekeres, Isabella Ellinger

Cancer Research (AACR) Austria, Romania, 09 April 2014

Medical Image Analysis

Key words:Biopsies, automated analysis

T cell-associated α4β7 but not α4β1 integrin is required for the induction and perpetuation of chronic colitis

E Kurmaeva, JD Lord, S Zhang, JR Bao, CG Kevil, MB Grisham & DV Ostanin

Mucosal Immunology (Nature) USA, 09 April 2014


Key words:Antibody therapy, Colitis, Crohn's disease, Mucosal immunology

Oncogenic functions of IGF1R and INSR in prostate cancer include enhanced tumor growth, cell migration and angiogenesis

I Heidegger, J Kern, P Ofer, H Klocker, P Massoner

Oncotarget (NCBI) Austria, 02 April 2014


Key words:Prostate cancer, IGF targeting therapies, insulin-like growth factor receptor-1 (IGF1R), insulin receptor (INSR)

Calcium-sensing receptor silencing in colorectal cancer is associated with promoter hypermethylation and loss of acetylation on histone 3

Irfete S. Fetahu, Julia Höbaus, Abhishek Aggarwal, Doris M. Hummel, Samawansha Tennakoon, Ildiko Mesteri, Sabina Baumgartner-Parzer, Eniko Kállay

IJC (Wiley) Austria, 02 April 2014


Key words:Calcium-sensing receptor, DNA methylation, histone acetylation, histone methylation, colorectal cancer

Protective effect of magnesium and metformin on endometrium and ovary in experimental diabetes mellitus

C Gales, C Zamfir, D Radulescu, B Stoica, M Nechifor

Magnesium research (John Libbey) Romania, 01 April 2014

Reproductive Medicine

Key words:magnesium, endometrium, ovary, diabetes mellitus

Transplantation of cyclic stretched fibroblasts accelerates the wound-healing process in streptozotocin-induced diabetic mice

E Lee, DY Kim, E Chung, EA Lee, KS Park, Y Son

Cell Transplantation (SAGE Journals) South Korea, 01 April 2014

Transplantation Medicine

Key words:Cell survival, Cyclic stretch, Mechanical stimulus, Angiogenesis, Wound healing

Oxygen therapy does not increase production and damage induced by reactive oxygen species in focal cerebral ischemia

Li Suna, Guido Wolfertsb, Roland Veltkamp

Neuroscience Letters (Elsevier) Germany, 28 March 2014


Key words:Cerebral ischemia, oxygen therapy, HBO, reactive oxygen species, SOD2

In vivo real-time fluorescence visualization and brain-targeting mechanisms of lipid nanocarriers with different fatty ester:oil ratios

Chih-Jen Wen, Tzu-Chen Yen, Saleh A Al-Suwayeh, Hui-Wen Chang, Jia-You Fang

Future Medicine (FSG) Taiwan, Saudi Arabia, 27 March 2014


Key words:Lipid nanocarriers, cetyl palmitate, squalene, sulforhodamine B

Myofibroblasts in Murine Cutaneous Fibrosis Originate From Adiponectin-Positive Intradermal Progenitors

Roberta Goncalves Marangoni, Benjamin D. Korman, Jun Wei, Tammara A. Wood, Lauren V. Grham, Michael L. Whithfield, Philipp E. Scherrr, Warren G. Tourtellott, John Varga

Arthritis and Rheumatology (Wiley) USA, 27 March 2014


Key words:Myofibroblasts, systemic sclerosis, growth factor β, canonical adipogenic markers

RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis

Marion Lapierre, Sandrine Bonnet, Caroline Bascoul-Mollevi, Imade Ait-Arsa, Stéphan Jalaguier, Maguy Del Rio, Michela Plateroti, Paul Roepman, Marc Ychou, Julie Pannequin, Frédéric Hollande, Malcolm Parker, and Vincent Cavailles1

The Journal of Clinical Investigation (American Society of Clinical Investigation) France, The Netherlands, UK, 25 March 2014


Ambivalent role of pFAK-Y397 in serous ovarian cancer-a study of the OVCAD consortium

Stefanie Aust, Katharina Auer, Anna Bachmayr-Heyda, Carsten Denkert, Jalid Sehouli, Ioana Braicu, Sven Mahner, Sandrina Lambrechts, Ignace Vergote, Christoph Grimm, Reinhard Horvat, Dan Cacsire Castillo-Tong, Robert Zeillinger Dietmar Pils

Molecular cancer (Springer) Austria, Germany, Belgium, 21 March 2014


Key words:FAK, pFAK, molecular subclassification, immunohistochemistry, prognosis, ovarian cancer

Protection against Dengue Virus Infection in Mice by Administration of Antibodies against Modified Nonstructural Protein 1

Shu-Wen Wan, Yi-Tien Lu, Chia-Hui Huang, Chiou-Feng Lin, Robert Anderson, Hsiao-Sheng Liu, Trai-Ming Yeh, Yu-Ting Yen, Betty A. Wu-Hsieh , Yee-Shin Lin

Plos One (PLOS) Taiwan, Canada, 21 March 2014


Key words:Hemorrhage, endothelial cells, platelets, complement system, dengue fever, hematoxylin staining, inoculation, macrophages

Lamin B2 prevents chromosome instability by ensuring proper mitotic chromosome segregation

T Kuga, H Nie, T Kazami, M Satoh, K Matsushita, F Nomura, K Maeshima, Y Nakayama & T Tomonaga

Oncogenesis (Nature) Japan, 17 March 2014


Key words:Chromosome segregation, Colorectal cancer, Mitotic spindle

Hedgehog Pathway Inhibition in Chondrosarcoma Using the Smoothened Inhibitor IPI-926 Directly Inhibits Sarcoma Cell Growth

Veronica T. Campbell, Puviindran Nadesan, S. Amanda Ali, Chang Ye Yale Wang, Heather Whetstone, Raymond Poon, Qingxia Wei, John Keilty, Jennifer Proctor, Lauren W. Wang, Suneel S. Apte, Karen McGovern, Benjamin A. Alman, Jay S. Wunder

Molecular Cancer Therapeutics (AACR) USA, Canada, 14 March 2014


Key words:Hedgehog (Hh) pathway, Chondrosarcoma, transmembrane receptor Patched

Blockade of Fas Signaling in Breast Cancer Cells Suppresses Tumor Growth and Metastasis via Disruption of Fas Signaling-initiated Cancer-related Inflammation

Qiuyan Liu, Qinchun Tan, Yuanyuan Zheng, Kun Chen, Cheng Qia, Nan Li, Qingqing Wang, Xuetao Cao

JBC (JBC) China, 13 March 2014


Key words:Breast Cancer, fas inflammation, prostaglandins, tumor metastases IL-6 MDSC PGE2

Interleukin-1β Attenuates Myofibroblast Formation and Extracellular Matrix Production in Dermal and Lung Fibroblasts Exposed to Transforming Growth Factor-β1

Masum M. Mia, Ruud A. Bank, Miriam Boersema

Plos One (PLOS) The Netherlands, 12 March 2014

Cell Biology

Key words:Fibroblasts, collagens, gene expression, fibrosis, immunofluorescence staining, tissue repair, cytokines, lungs

5th International meeting on angiogenesis

Angiogenesis (Springer) The Netherlands, 08 March 2014

Regenerative Medicine

Impact of the Smoothened Inhibitor, IPI-926, on Smoothened Ciliary Localization and Hedgehog Pathway Activity

Marisa O. Peluso, Veronica T. Campbell, Joseph A. Harari, Thomas T. Tibbitts, Jennifer L. Proctor, Nigel Whitebread, James M. Conley, Kerry F. White, Jeffery L. Kutok, Margaret A. Read, Karen McGovern, Kerrie L. Faia

Plos One (PLOS) USA, 07 March 2014


Key words:Hedgehog signaling NIH 3T3 cells, cancer treatment, cell binding assay, cilia, gene expression, luciferase, cell staining

Excessive activation of the alternative complement pathway in autosomal dominant polycystic kidney disease

Z. Su, X. Wang, Gao,Y.Liu, C.Pan, H. Hu, R. P. Beyer, M. Shi, J. Zhou, J. Zhang, A. L. Serra, R. P. Wüthrich, C. Mei

Journal of Internal Medicine (Wiley) China, Switzerland, USA, 02 March 2014


Key words:Autosomal dominant polycystic kidney disease, complement, complement inhibitor, glycoproteomics, urine

AB0206 Altered Expression of Angiopoietins and Tie-2 in Ischemic Lesions of UCD-206 Chickens, an Animal Model for Systemic Sclerosis

S. Allipour Birgani, H. Dietrich, R. Sgonc

Annals of Rheumatic Diseases (BMJ) Austria, 01 March 2014


Key words:Systemic sclerosis, vascular endothelial growth factor , endothelial cells

Multimodality imaging to assess immediate response to irreversible electroporation in a rat liver tumor model

Yue Zhang, Sarah B. White, Jodi R. Nicolai, Zhuoli Zhang, Derek L. West, Dong-hyun Kim, A. Lee Goodwin, Frank H. Miller, Reed A. Omary, Andrew C. Larson

Radiology (RSNA) USA, 18 February 2014


Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma

Winnie W. Lo, Jay S. Wunder, Brendan C. Dickson, Veronica Campbell, Karen McGovern , Benjamin A. Alman, Irene L. Andrulis

Cancer (Wiley) Canada, USA, 15 February 2014


Key words:Osteosarcoma, hedgehog signaling, ligand-dependent,IPI-926, microenvironment

Iron deficiency alters megakaryopoiesis and platelet phenotype independent of thrombopoietin

Rayko Evstatiev, Adam Bukaty, Kristine Jimenez, Stefanie Kulnigg-Dabsch, Lidia Surman, Werner Schmid, Robert Eferl, Kathrin Lippert, Barbara Scheiber-Mojdehkar, Hans Michael Kvasnicka, Vineeta Khare, Christoph Gasch

American Journal of Hematology (Wiley) Austria, Germany, 14 February 2014


Key words:Iron deficiency

NKG2D+ IFN-γ+ CD8+ T Cells Are Responsible for Palladium Allergy

Mitsuko Kawano, Masafumi Nakayama, Yusuke Aoshima, Kyohei Nakamura, Mizuho Ono, Tadashi Nishiya, Syou Nakamura, Yuri Takeda, Akira Dobashi, Akiko Takahashi, Misato Endo, Akiyo Ito, Kyosuke Ueda, Naoki Sato, Shigehito Higuchi, Takeru Kondo, Suguru Hashimot

Plos One (PLOS) Japan, 12 February 2014


Key words:T cells, cytotoxic T cells, allergies, mouse models, adoptive transfer, lymphocytes, allergy immunotherapy, lymph nodes

Successful treatment of adult onset Langerhans cell histiocytosis with bi-weekly administration of pegylated interferon-α

Sadanori Furudate, Taku Fujimura, Yumi Kambayashi, Mitsuko Kawano, Kouetsu Ogasawara, Akira Tsukada, Erika Tamabuchi, Takahiro Haga, Akira Hashimoto and Setsuya Aiba

Acta Dermato Venereologica (ingentaconnect) Japan, 04 February 2014


Serum Level of IL-10 Is Increased in Patients with Endometriosis, and IL-10 Promotes the Growth of Lesions in a Murine Model

Jau-Ling Suen, Yu Chang, Pu-Rong Chiu, Tsung-Hua Hsieh, Edward Hsi, Yu-Chieh Chen, Yu-Fang Chen, Eing-Mei Tsai

Elsevier (Elsevier) Taiwan, 01 February 2014


Key words:Immune dysregulation, anti-inflammatory cytokine IL-10, Monocyte-derived dendritic cells

Role of oncogenic K-Ras in cancer stem cell activation by aberrant Wnt/β-catenin signaling

BS Moon, WJ Jeong, J Park, TI Kim, DS Min, KY Choi

Journal of the National Cancer Institute (Oxford Academic) South Korea, 31 January 2014


Key words:signal transduction, mutation, cd44 antigens, transplantation, heterologous, mice, neoplasms, k-ras oncogene, homing-associated cell adhesion molecule, cancer stem cells

Metformin anti-tumor effect via disruption of the MID1 translational regulator complex and AR downregulation in prostate cancer cells

Ummuhan Demir, Andrea Koehler, Rainer Schneider, Susann Schweiger, Helmut Klocker

Springer (Springer) Austria, Germany, 31 January 2014


Key words:Metformin, Androgen receptor, MID1-α4/PP2A protein complex, AMPK ,Translational regulation, CoIP

Die prognostische Bedeutung von Tumor-infiltrierenden CD8+Zellen: eine detaillierte Analyse in Hinblick auf Tumor-Debulking und Zell-Proliferation

S Aust, A Bachmayr-Heyda, S Polterauer, D Pils, DC Castillo-Tong, OVCAD Consortium

Thieme (Thieme) Austria, 30 January 2014


A dual role for autophagy in a murine model of lung cancer

Shuan Rao, Luigi Tortola, Thomas Perlot, Gerald Wirnsberger, Maria Novatchkova, Roberto Nitsch, Peter Sykacek, Lukas Frank, Daniel Schramek, Vukoslav Komnenovic, Verena Sigl, Karin Aumayr, Gerald Schmauss, Nicole Fellner, Stephan Handschuh, Martin Glösman

Nature Communications (Nature) Austria, France, 20 January 2014


Key words:Autophagy, Lung cancer, Oncogenesis

The role of the organic anion transporting polypeptide OATP4A1 in immunactivation in colorectal cancer and inflammatory colon disease.

Christoph Alexander Ausch, Simone Zotter, Maidah Scheikh, Heike Bauer, Marina Mollik, Erika Bajna, Christian Sebesta, Angelika Reiner, Theresia Thalhammer and Veronika Buxhofer-Ausch

American Society of Clinical Oncology (American Society of Clinical Oncology) , 20 January 2014


Key words:Prostaglandins, cyclic nucleotides, second messenger proteins, tumor cells growth

Glycogen Synthase Kinase 3β (GSK3β) Regulates Differentiation and Proliferation in Neural Stem Cells from the Rat Subventricular Zone 1

Martin H. Maurer, Jens O. Brömme, Robert E. Feldmann, Jr Anne Järve, Fatemeh Sabouri, Heinrich F. Bürgers, Dominik W. Schelshorn, Carola Krüger, Armin Schneider, Wolfgang Kuschinsky

ACS Publications (ACS Publications) Germany, 18 January 2014

Stem Cell Research

Key words:Neural stem cell, Neurosphere, Glycogen Synthase Kinase 3β, Two-dimensional gel electrophoresis, Rat, Subventricular zone

Hepatic RIG-I Predicts Survival and Interferon-α Therapeutic Response in Hepatocellular Carcinoma

Jin Hou, Ye Zhou, Yuanyuan Zheng, Jia Fan, Weiping Zhou, Irene O.L. Ng, Huichuan Sun, Lunxiu Qin, Shuangjian Qiu, Joyce M.F. Lee, Chung-Mau Lo, Kwan Man, Yuan Yang, Yun Yang, Yingyun Yang, Qian Zhang, Xuhui Zhu, Nan Li, Zhengxin Wang, Guoshan Ding, Shi-Me

Elsevier (Elsevier) China, 13 January 2014


Key words:Hepatocellular carcinoma, interferon-α, retinoic acid-inducible gene-I

Diverse T-cell responses characterize the different manifestations of cutaneous graft-versus-host disease

Marie-Charlotte Brüggen, Irene Klein, Hildegard Greinix, Wolfgang Bauer, Zoya Kuzmina, Werner Rabitsch, Peter Kalhs, Peter Petzelbauer, Robert Knobler, Georg Stingl, Georg Stary

ASH (ASH) Austria, 09 January 2014

Transplantation Medicine

Key words:Distinct T-cell patterns characterize the acute and chronic forms of cutaneous GVHD, increased TSLP expression is an indicator of acute cutaneous GVHD development.


Vrânceanu, Anca; Tărniceriu, Claudia Cristina; Makkai, S.; Carasevici, E.

( Romania, 01 January 2014


Lymph node status assessed through the log odds ratio–a better tool in the prognosis of colorectal cancer relapse

ST Makkai-Popa, S Luncă, E Târcoveanu, E Carasevici, G Dimofte

Romanian Journal of Morphology and Embryology () Romania, 01 January 2014


Key words:disease-free interval, lymph node ratio, log odds ratio.

Macrophage Quantification in Different Breast Tumor Compartments.

Haisan, Anca; Petreus, T.; Jitaru, Daniela; Danciu, M.; Carasevici, E.

Jurnalul de … ( Romania, 01 January 2014


Resveratrol enhances the chemopreventive effect of celecoxib in chemically induced breast cancer in rats

Terézia Kisková, Rastislav Jendzelovsky, Erdenetsetsek Rentsen, Alexandra Maier-Salamon, Natalia Kokosova, Zuzana Papcova,Jaromır Mikes, Peter Orendas, Bianka Bojkova, Peter Kubatka, Martin Svoboda, Karol Kajo, Peter Fedorocko, Walter Jager, Cem Ekmekciog

European Journal of Cancer Prevention (Wolters Kluwer) Austria, 01 January 2014


Key words:celecoxib, chemically induced breast cancer, COX2, GDF15, MCF-7 cells, oxidative stress, resveratrol

Role of endocytic uptake in transfection efficiency of solid lipid nanoparticles-based nonviral vectors

Aritz Perez Ruiz de Garibay, María Ángeles Solinís Aspiazu, Alicia Rodríguez Gascón, Haleh Ganjian, Renate Fuchs

The Journal of Gene Medicine (Wiley) Spain, Austria, 27 December 2013


Key words:Endocytosis, lysosome, nonviral vector, solid lipid nanoparticles, transfection

Ginsenoside Rg3 Up-regulates the Expression of Vascular Endothelial Growth Factor in Human Dermal Papilla Cells and Mouse Hair Follicles

Dae Hyun Shin, Youn Jeong Cha, Kyeong Eun Yang, Ik-Soon Jang, Chang-Gue Son, Bo Hyeon Kim, Jung Min Kim

Phytotherapy Research (Wiley) South Korea, 26 December 2013


Key words:Rg3, hair growth, DP cell, gene expression profiles, VEGF, stemness marker

Application of quinidine on rat sciatic nerve decreases the amplitude and increases the latency of evoked responses

Kuang-I Cheng, I-Ling Lin, Lin-Li Chang, I-Ming Jou, Chung-Sheng Lai, Jhi-Joung Wang, Hung-Chen Wang, Aij-Lie Kwan

Journal of Anesthesia (Springer) Taiwan, 15 December 2013


Key words:Sciatic nerve, lidocaine, sciatic nerve fiber, contralateral hind limb, rat sciatic nerve, quinidine concentration, sodium channel, ranvier node, myelinated nerve fiber, local anesthetic, nerve conduction, peripheral nerve, neuropathic pain, conduction ve

Autophagy suppresses tumorigenesis of hepatitis B virus-associated hepatocellular carcinoma through degradation of microRNA-224

Sheng-Hui Lan, Shan-Ying Wu, Roberto Zuchini, Xi-Zhang Lin, Ih-Jen Su, Ting-Fen Tsai, Yen-Ju Lin, Cheng-Tao Wu and Hsiao-Sheng Liu

Hepatology (Wiley) Taiwan, 13 December 2013


Key words:microRNA-224, miR‐224 antagonist, autophagosome fraction, autophagy‐related genes, chloroquine, double distilled water, digoxigenin, hepatitis B virus, hepatitis B virus X protein, hepatocellular carcinoma, hepatitis C virus

Overexpression of FGF9 in colon cancer cells is mediated by hypoxia-induced translational activation

Tsung-Ming Chen, Yu-Heng Shih, Joseph T. Tseng, Ming-Chih Lai, Chih-Hao Wu, Yi-Han Li, Shaw-Jenq Tsai, H. Sunny Sun

Nucleic Acids Research (Oxford Journals) Taiwan, 10 December 2013


Key words:Human fibroblast growth factor 9 , hypoxia, colon cancer cells

Localized Hyperthermia with Iron Oxide–Doped Yttrium Microparticles: Steps toward Image-Guided Thermoradiotherapy in Liver Cancer

Andrew C. Gordon, Robert J. Lewandowski, Riad Salem,, Delbert E. Day, Reed A. Omary, Andrew C. Larson

Journal of Vascular and Interventional Radiology (Elsevier) USA, 06 December 2013


Key words:Hepatocellular carcinoma, normal hepatic parenchyma, alternating magnetic field

MAR-mediated integration of plasmid vectors for in vivo gene transfer and regulation

Stefania Puttini, Ruthger W van Zwieten, Damien Saugy, Malgorzata Lekka, Florence Hogger, Deborah Ley, Andrzej J Kulik, Nicolas Mermod

BMC Molecular Biology (Springer) Switzerland, Poland, 02 December 2013


Key words:Inducible expression, non-viral vectors, MAR elements, erythropoietin, utrophin, gene therapy

Langerhans cell maturation is accompanied by induction of N-cadherin and the transcriptional regulators of epithelial–mesenchymal transition ZEB1/2

Sabine Konradi, Nighat Yasmin1, Denise Haslwanter, Michele Weber, Bernhard Gesslbauer, Michael Sixt, Herbert Strobl

European Journal of Immunology (Wiley) Austria, 02 December 2013


Key words:Cell migration, dendritic cells, epithelial-to-mesenchymal transition, langerhans cells, maturation

Transdifferentiation of Adipose-Derived Stem Cells into Keratinocyte-Like Cells: Engineering a Stratified Epidermis

Claudia Chavez-Munoz, Khang T. Nguyen,Wei Xu, Seok-Jong Hong,Thomas A. Mustoe, Robert D. Galiano

Plos One (PLOS) USA, 02 December 2013

Stem Cell Research

Key words:Keratinocytes, cell staining, transdifferentiation, cell differentiation, mesenchymal stem cells, DAPI staining, antibiotics, fibroblasts

A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog

Astrid Hagelkruys, Sabine Lagger, Julia Krahmer, Alexandra Leopoldi, Matthias Artaker, Oliver Pusch, Jürgen Zezua, Simon Weissmann, Yunli Xie, Christian Schöfer, Michaela Schlederer, Gerald Brosch, Patrick Matthias, Jim Selfridge, Hans Lassmann, Jürgen A.

Development (The Company of Biologists) Austria, Switzerland, UK, 19 November 2013


Key words:Histone deacetylases, neural cells, histone acetyltransferases, central nervous system

Developmental and oncogenic radiation effects on neural stem cells and their differentiating progeny in mouse cerebellum

Mirella Tanori, Emanuela Pasquali, Simona Leonardi, Arianna Casciati, Paola Giardullo, Ilaria De Stefano, Mariateresa Mancuso, Anna Saran, Simonetta Pazzaglia

Stem Cells (Wiley) Italy, 15 November 2013

Stem Cell Research

Key words:Ptc1+/- mice, apoptosis, DNA repair, p21, medulloblastoma, carcinogenesis, neural stem cells, progenitor cells

Epidermal Growth Factor Receptor Targeted Nuclear Delivery and High-Resolution Whole Cell X-ray Imaging of Fe3O4@TiO2 Nanoparticles in Cancer Cells

Ye Yuan, Si Chen, Tatjana Paunesku, Sophie Charlotte Gleber, William C. Liu, Caroline B. Doty, Rachel Mak, Junjing Deng, Qiaoling Jin, Barry Lai, Keith Brister, Claus Flachenecker, Chris Jacobsen, Stefan Vogt, Gayle E. Woloschak

ACS Nano (ACS Publications) USA, 12 November 2013

Medical Imaging

Key words:Nanoparticles, titanium dioxide, photoactivation, X-ray fluorescence microscopy, epidermal growth factor receptor

Cardiac magnetic resonance postcontrast T1 time is associated with outcome in patients with heart failure and preserved ejection fraction

Mascherbauer J, Marzluf BA, Tufaro C, Pfaffenberger S, Graf A, Wexberg P, Panzenböck A, Jakowitsch J, Bangert C, Laimer D, Schreiber C, Karakus G, Hülsmann M, Pacher R, Lang IM, Maurer G, Bonderman D.

Circulation:Cardiovascular Imaging (AHA Journals) Austria, Turkey, 06 November 2013


Key words:Hypertension, pulmonary, magnetic resonance imaging, prognosis

Alcohol Exacerbates LPS-Induced Fibrosis in Subclinical Acute Pancreatitis

Haitao Gu, Franco Fortunato, Frank Bergmann, Markus W. Büchler, David C. Whitcomb, Jens Werner

American journal of Pathology (Elsevier) Germany, 01 November 2013


Key words:Pancreatic acinar cells, alcoholic acute pancreatitis, growth factor-β of acinar cells, pancreatic fibrosis

Targeting of sodium–glucose cotransporters with phlorizin inhibits polycystic kidney disease progression in Han: SPRD rats

X Wang, S Zhang, Y Liu, D Spichtig, S Kapoor, H koepsell, N Mohebbi, S Sergerer, AL Serra, D Rodriguez, O Devuyst, C Mei, RP Wüthrich

Kidney international (Elsevier) Switzerland, China, Germany, 01 November 2013


Key words:polycystic, phlorizin, rat, sodium–glucose cotransport

Corelation of Lymphocytic Infiltrates with the Prognosis of Recurrent Colo-Rectal Cancer

ST Makkai-Popa, S Luncã, G Dimofte, A Vrânceanu, D. Franciug, I Ivanov, F Zugun, E Târcoveanu, E Carasevici

Chirurgia (revistachirurgia) Romania, 01 November 2013


Key words:relapse prognosis, colo-rectal cancer, quantitative assessment of immunohistochemical staining, digital image analysis, cytotoxic T cells

Hypercapnia Impairs Lung Neutrophil Function and Increases Mortality in Murine Pseudomonas Pneumonia

Khalilah L. Gates , Heather A. Howell , Aisha Nair , Christine U. Vohwinkel , Lynn C. Welch , Greg J. Beitel , Alan R. Hauser , Jacob I. Sznajder , and Peter H. S. Sporn

American journal of respiratory cell and molecular biology (ATS Journals) USA, 01 November 2013


Key words:arbon dioxide; pulmonary infection; reactive oxygen species; phagocytosis; inflammation

Renal Heparan Sulfate Proteoglycans Modulate Fibroblast Growth Factor 2 Signaling in Experimental Chronic Transplant Dysfunction

Kirankumar Katta, Miriam Boersema, Saritha Adepu, Heleen Rienstra, Johanna W.A.M. Celie, Rik Mencke, Grietje Molema, Harry van Goor, Jo H.M. Berden, Gerjan Navis, Jan-Luuk Hillebrands, Jacob van den Born

The American Journal of Pathology (Elsevier) The Netherlands, 01 November 2013

Transplantation Medicine

Key words:Renal transplantation, proteoglycans, chronic transplant dysfunction, laser-microdissected glomeruli

AKIP1, a cardiac hypertrophy induced protein that stimulates cardiomyocyte growth via the Akt pathway

H Yu, W Tigchelaar, B Lu, WH van Gilst, RA De Boer, B Daan Westenbrink, HHW Sillje

International journal of Molecular Sciences (MDPI) The Netherlands, China, 28 October 2013


Key words:cardiac hypertrophy; AKIP1; Akt; kinase; remodeling

Regulation of the calcium-sensing receptor expression by 1,25-dihydroxyvitamin D3, interleukin-6, and tumor necrosis factor alpha in colon cancer cells

Irfete S. Fetahu, Doris M. Hummel, Teresa Manhardt, Abhishek Aggarwal, Sabina Baumgartner-Parzer, Eniko Kállay

The Journal of Steroid Biochemistry and Molecular Biology (Elsevier) Austria, 28 October 2013


Key words:Calcium-sensing receptor, colon cancer, tumor necrosis factor alpha, interleukin, 1,25-dihydroxyvitamin D3, Inflammation

Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie

Oncology research and treatment (Karger) Austria, 22 October 2013


Effects on tumor development and metastatic dissemination by the NKG2D lymphocyte receptor expressed on cancer cells

A El-Gazzar, X Cai, R S Reeves, Z Dai, A Caballero-Benitez, D L McDonald, J Vazquez, T A Gooley, G E Sale, T Spies & V Groh

Oncogene (Nature) USA, 21 October 2013


Key words:Breast cancer, Metastasis, Oncogene proteins, Oncogenesis

Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation

Marco Peviani, Eleonora Salvaneschi, Leonardo Bontempi, Alessandro Petese, Antonio Manzo, Daniela Rossi, Mario Salmona, Simona Collina, Paolo Bigini, Daniela Curti

Neurobiology of Disease (Elsevier) Italy, 16 October 2013


Key words:Sigma-1 receptor, motor neurons, BDNF, reactive gliosis, neurodegeneration, obbler

Overexpression of the Transcriptional Repressor Complex BCL-6/BCoR Leads to Nuclear Aggregates Distinct from Classical Aggresomes

Elisabeth Buchberger, Miriam El Harchi, Dietmar Payrhuber, Anna Zommer, Dominic Schauer, Ingrid Simonitsch-Klupp, Martin Bilban, Christine Brostjan

Plos One (PLOS) Austria, 11 October 2013

Cell Biology

Key words:Transfection, chaperone proteins, heat shock response, plasmid construction, cell staining, immunostaining, nuclear bodies, protein structure

Suberoylanilide Hydroxamic Acid, an Inhibitor of Histone Deacetylase, Enhances Radiosensitivity and Suppresses Lung Metastasis in Breast Cancer In Vitro and In Vivo

Hui-Wen Chiu, Ya-Ling Yeh, Yi-Ching Wang, Wei-Jan Huang, Yi-An Chen, Yi-Shiou Chiou, Sheng-Yow Ho, Pinpin Lin, Ying-Jan Wang

Plos One (PLOS) Taiwan, 10 October 2013


Key words:Cancer treatment, autophagic cell death, breast cancer, DNA damage, apoptosis, metastasis, fluorescence microscopy, DNA repair

Characterization of T Cell Receptors of Th1 Cells Infiltrating Inflamed Skin of a Novel Murine Model of Palladium-Induced Metal Allergy

Hiroshi Kobayashi, Kenichi Kumagai, Takanori Eguchi, Hiroaki Shigematsu, Kazutaka Kitaura, Mitsuko Kawano, Tatsuya Horikawa, Satsuki Suzuki, Takaji Matsutani, Kouetsu Ogasawara, Yoshiki Hamada, Ryuji Suzuki

Plos One (PLOS) Japan, 03 October 2013


Key words:T cells, allergies, T cell receptors, polymerase chain reaction, cytokines, inflammation, chemokines, sequence analysis

Necro-inflammatory response of pancreatic acinar cells in the pathogenesis of acute alcoholic pancreatitis

H Gu, J Werner, F Bergmann, DC Whitcomb, MW Büchler, F Fortunato

Cell death & Disease (Nature) Germany, USA, 03 October 2013


Key words:Acute pancreatitis, Inflammation, Necroptosis

Comparison of Interleukin-17- Producing Cells in Different Clinical Types of Alopecia Areata

Tojo G., Fujimura T., Kawano M., Ogasawara K., Kambayashi Y.,Furudate S., Mizuashi M., Aiba S.

Dermatology (Karger) Japan, 01 October 2013


Key words:Alopecia areata Interleukin-17 Interferon Acute, diffuse and total alopecia

Up-Regulation of SOX9 in Sertoli Cells from Testiculopathic Patients Accounts for Increasing Anti-Mullerian Hormone Expression via Impaired Androgen Receptor Signaling

Kuo-Chung Lan, Yen-Ta Chen, Chawnshang Chang, Yung-Chiao Chang, Hsin-Jung Lin, Ko-En Huang, Hong-Yo Kang

Plos One (PLOS) Taiwan, USA, 01 October 2013


Key words:Sertoli cells, testes, androgens, spermatogenesis, reverse transcriptase-polymerase chain reaction, testosterone, adults, germ cells

Expression Of CD8 Is Associated With Non-Common Type Morphology And Outcome In Pediatric Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma

Dmitriy Abramov, Ilske Oschlies, Martin Zimmermann, Dmitriy Konovalov, Christine Damm-Welk, Wilhelm Wössmann, Wolfram Klapper

Haematologica (EHA) Germany, Russia, 01 October 2013


Key words:Anaplastic lymphoma kinase, CD30-positive T-cell lymphoma, vinblastine, autologous, allogeneic hematopoietic stem cell transplantation

Digital immunohistochemistry: new horizons and practical solutions in breast cancer pathology

Arvydas Laurinavicius, Justinas Besusparis, Justina Didziapetryte, Gedmante Radziuviene, Raimundas Meskauskas Aida Laurinaviciene

Diagnostic Pathology (BioMed Central) Lithuania, 30 September 2013


Key words:Breast cancer, Immunohistochemistry (IHC) biomarkers, tissue microarray

Loss of phosphatase and tensin homolog (PTEN) in myeloid cells controls inflammatory bone destruction by regulating the osteoclastogenic potential of myeloid cells

Stephan Blüml, Martin Friedrich, Tobias Lohmeyer, Emine Sahin, Victoria Saferding, Julia Brunner, Antonia Puchner, Peter Mandl, Birgit Niederreiter, Josef S Smolen, Gernot Schabbauer, Kurt Redlich

Annals of the Rheumatic Disease (BMJ) Austria, 27 September 2013


Key words:Rheumatic diseases, osteoclasts, Phosphoinositide-3-Kinase, Phosphatase and tensin homolog

Direct Comparison of Autologous and Allogeneic Transplantation of iPSC-Derived Neural Cells in the Brain of a Nonhuman Primate

Morizane A, Doi D, Kikuchi T, Okita K, Hotta A, Kawasaki T, Hayashi T, Onoe H, Shiina T, Yamanaka S, Takahashi J.

Stem Cell Reports (Cell Press) Japan, 26 September 2013

Transplantation Medicine

Prognostic impact of tumor infiltrating CD8+ T cells in association with cell proliferation in ovarian cancer patients - a study of the OVCAD consortium

Anna Bachmayr-Heyda, Stefanie Aust, Georg Heinze, Stephan Polterauer, Christoph Grimm, Elena Ioana Braicu, Jalid Sehouli, Sandrina Lambrechts, Ignace Vergote, Sven Mahner, Dietmar Pils, Eva Schuster, Theresia Thalhammer, Reinhard Horvat, Carsten Denkert,

BMC Cancer (BioMed Central) Austria, Germany, Belgium, 17 September 2013


Key words:Epithelial ovarian cancer, Cytotoxic T cells, Tumor proliferation, Prognostic impact, Residual tumor

A single extra copy of Dscr1 improves survival of mice developing spontaneous lung tumors through suppression of tumor angiogenesis

Jimin Shin, Jang Choon Lee, Kwan-Hyuck Baek

Cancer Letters (Elsevier) South Korea, 16 September 2013


Key words:Down syndrome, cancer, angiogenesis, Dscr1, Spontaneous lung tumorigenesis

Contribution of Toll-Like Receptor 2 to the Innate Response against Staphylococcus aureus Infection in Mice

Yimin, Masashi Kohanawa, Songji Zhao, Michitaka Ozaki,Sanae Haga, Guangxian Nan, Yuji Kuge, Nagara Tamaki

Plos One (PLOS) Japan, China, 13 September 2013


Key words:Staphylococcus aureus, macrophages, cytokines, bacterial pathogens, toll-like receptors, neutrophils, gene expression, blood

Comprehensive characterizations of nanoparticle biodistribution following systemic injection in mice

WY Liao, HJ Li, MY Chang, ACL Tang, AS Hoffman, PCH Hsieh

Nanoscale (Royal Society of Chemistry) Taiwan, USA, 06 September 2013


Digital microscopy assessment of angiogenesis in different breast cancer compartments

Haisan A, Rogojanu R, Croitoru C, Jitaru D, Tarniceriu C, Danciu M, Carasevici E.

Biomedical Research International (Hindawi Publishing Corporation) Romania, Austria, 01 September 2013

Medical Image Analysis

Key words:Tumour angiogenesis, microvessel density, breast cancer, tumour associated stroma, tumour parenchyma, tumour invasive front.

In vitro and in vivo uptake study of Escherichia coli Nissle 1917 bacterial ghosts: cell-based delivery system to target ocular surface diseases

Elisabeth Stein; Aleksandra Inic-Kanada; Sandra Belij; Jacqueline Montanaro; Nora Bintner; Simone Schlacher; Ulrike Beate Mayr; Werner Lubitz; Marijana Stojanovic; Hristo Najdenski; Talin Barisani-Asenbauer

Investigative Ophthalmology & Visual Science (ARVO Journals) Austria, Serbia, Bulgaria, 01 September 2013


Expression of E-cadherin, Twist, and p53 and their prognostic value in patients with oral squamous cell carcinoma

Chi-Chen Fan, Tao-Yeuan Wang, Yen-An Cheng, Shih Sheng Jiang, Chien-Wen Cheng, Alan Yueh-Luen Lee, Ting-Yu Kao

Journal of Cancer Research and Clinical Oncology (Springer) Taiwan, 30 August 2013


Key words:Ttwist expression, betel quid, betel quid chewing, oscc tissue, reduced e-cadherin,oscc tumor, oral cancer, oral squamous cell carcinoma, oral carcinogenesis, neck cancer, oral epithelium, emt marker, bladder cancer, e-cadherin promoter, emt transcription

Involvement of the Serine Protease Inhibitor, SERPINE2, and the Urokinase Plasminogen Activator in Cumulus Expansion and Oocyte Maturation

Chung-Hao Lu, Robert Kuo-Kuang Lee, Yuh-Ming Hwu, Ming-Huei Lin, Ling-Yu Yeh, Ying-Jie Chen, Shau-Ping Lin, Sheng-Hsiang Li

Plos One (PLOS) Taiwan, 30 August 2013

Reproductive Medicine

Key words:Oocytes, small interfering RNAs, extracellular matrix, immune serum, ovaries, vector cloning, complementary DNA, gene expression

Glycogen synthase kinase-3β–mediated CCAAT/enhancer-binding protein delta phosphorylation in astrocytes promot es migration and activation of microglia/macrophages

Chiung-Yuan Ko, Wen-Ling Wang, Shao-Ming Wang, Yu-Yi Chu, Wen-Chang Chang, Ju-Ming Wang

Neurobiology of aging (Elsevier) Taiwan, Japan, 29 August 2013


Key words:Alzheimer's disease, CEBPD, GSK3ß, astrocytes, microglia

Human Cytomegalovirus UL76 Elicits Novel Aggresome Formation via Interaction with S5a of the Ubiquitin Proteasome System

Shin-Rung Lin, Meei Jyh Jiang, Hung-Hsueh Wang, Cheng-Hui Hu, Ming-Shan Hsu, Edward Hsi, Chang-Yih Duh, Shang-Kwei Wang

Journal of Virology (ASM) China, 21 August 2013


Key words:Cytomegalovirus

Neohesperidin attenuates cerebral ischemia–reperfusion injury via inhibiting the apoptotic pathway and activating the Akt/Nrf2/HO-1 pathway

Journal of Asian Natural Products Research (Taylor & Francis) China, 16 August 2013


Key words:Cerebral ischemia

Panton-Valentine Leukocidin Facilitates the Escape of Staphylococcus aureus From Human Keratinocyte Endosomes and Induces Apoptosis

Chia-Yu Chi, Chia-Chun Lin, I-Chuang Liao, Yi-Chuan Yao, Fan-Ching Shen, Ching-Chuan Liu, Chiou-Feng Lin

The Journal of Infectious Disease (Oxford Journals) Taiwan, 15 August 2013


Key words:Endosome keratinocyte, Panton-Valentine leukocidin, Staphylococcus aureus

Circulating alpha-klotho levels are not disturbed in patients with type 2 diabetes with and without macrovascular disease in the absence of nephropathy

Joris van Ark, Hans-Peter Hammes, Marcory C R F van Dijk, Marc G Vervloet, Bruce H R Wolffenbuttel, Harry van Goor, Jan-Luuk Hillebrands

Cardiovascular Diabetology (Springer) The Netherlands, Germany, 14 August 2013


Key words:Vascular, diabetes

Carboxyl-Terminal Modulator Protein Positively Regulates Akt Phosphorylation and Acts as an Oncogenic Driver in Breast Cancer

Yu-Peng Liu, Wen-Chi Liao, Luo-Ping Ger, Jiun-Chin Chen, Tai-I Hsu, Yu-Cheng Lee, Hong-Tai Chang, Yu-Chia Chen, Yi-Hua Jan, Kuen-Haur Lee, Yu-Hao Zeng, Michael Hsiao, Pei-Jung Lu

Cancer Research (AACR) Taiwan, 13 August 2013


Key words:Tumorigenesis, cancer cells, carboxy-terminal modulator protein, Akt serine/threonine kinase

A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis

Karoline Kollmann, Gerwin Heller, Christine Schneckenleithner, Wolfgang Warsch, Ruth Scheicher, Rene G. Ott, Markus Schäfer, Sabine Fajmann, Michaela Schlederer, Ana-Iris Schiefer, Ursula Reichart, Matthias Mayerhofer, Christoph Hoeller, Sabine Zöchbauer-

Cancer Cell (Elsevier) Austria, UK, Spain, 12 August 2013


Key words:Cell cycle kinase CDK6, pro-angiogenic factor VEGF-A, tumor suppressor p16INK4a

Quantitative magnetization transfer MRI of desmoplasia in pancreatic ductal adenocarcinoma xenografts

Weiguo Li, Zhuoli Zhang, Jodi Nicolai, Guang-Yu Yang, Reed A. Omary, Andrew C. Larson

NMR in Biomedicine (Wiley) USA, 12 August 2013


Key words:Quantitative magnetization transfer, bound proton fraction, desmoplasia, pancreatic cancer, xenograft

An interleukin-17–mediated paracrine network promotes tumor resistance to anti-angiogenic therapy

Alicia S Chung, Xiumin Wu, Guanglei Zhuang, Hai Ngu, Ian Kasman, Jianhuan Zhang, Jean-Michel Vernes, Zhaoshi Jiang, Y Gloria Meng, Franklin V Peale, Wenjun Ouyang & Napoleone Ferrara

Nature Medicine (Nature) USA, 04 August 2013


Key words:Cancer

Entry of human rhinovirus 89 via ICAM-1 into HeLa epithelial cells is inhibited by actin skeleton disruption and by bafilomycin

Beatrix Pfanzagl, Daniel Andergassen, Johanna Edlmayr, Katarzyna Niespodziana, Rudolf Valenta, Dieter Blaas

Archives of Virology (Springer) Austria, 04 August 2013


Key words:Hela cell, transferrin, rhabdomyosarcoma, confocal immunofluorescence microscopy, cholesterol depletion, dextran, skeletal muscle cell, stress fiber formation, actin aggregate,lipid raft, breast cancer cell line, infected hela cell, actin patch, rock inhi

Interleukin-1β induced by Helicobacter pylori infection enhances mouse gastric carcinogenesis

Yasuyuki Shigematsu, Tohru Niwa, Emil Rehnberg, Takeshi Toyoda, Satoshi Yoshida, Akiko Mori, Mika Wakabayashi, Yoichiro Iwakura, Masao Ichinose, Yong-Joon Kim, Toshikazu Ushijima

Cancer Letters (Elsevier) Japan, South Korea, 03 August 2013


Key words:Interleukin-1ß, gastric cancer, helicobacter pylori infection, inflammation

Impact of constant storage temperatures and multiple warming cycles on the quality of stored red blood cells

T. Wagner, M.-A. Pabst, G. Leitinger, U. Reiter, N. Kozma, G. Lanzer, B. Huppertz

VoxSanguinis (Wiley) Austria, 02 August 2013


Key words:Electron microscopy, quality, RBC, storage, temperature.

Mobilizing monocytes to cross-present circulating viral antigen in chronic infection

Adam J. Gehring, Muzlifah Haniffa, Patrick T. Kennedy, Zi Zong Ho, Carolina Boni, Amanda Shin, Nasirah Banu, Adeline Chia, Seng Gee Lim, Carlo Ferrari, Florent Ginhoux, Antonio Bertolett

The Journal of Clinical Investigation (American Society of Clinical Investigation) Singapore, UK, Italy, 01 August 2013


Decreased hippocampal MR/GR ratio is associated with low-birth weight in Cynomolgus macaque neonates

JP Buschdorf, SX Ong, K Chng, MJ Meany

Journal of molecular endocrinology (Society for Endocrinology) Singapore, 01 August 2013

Reproductive Medicine

Key words:MR:GR ratio; cynomolgus macaque; glucocorticoid receptor; low birth weight

Infliximab induces downregulation of the IL-12/IL-23 axis in 6-sulfo-LacNac (slan)+ dendritic cells and macrophages

Patrick M. Brunner, Frieder Koszik, Bärbel Reininger, Madeleine L. Kalb, Wolfgang Bauer, Georg Stingl

Journal of Allergy and Clinical Immunology (Elsevier) Austria, 25 July 2013


Key words:Psoriasis, myeloid dendritic cells, 6-sulfo-LacNac, IL-12p40, TNF-a

Association of gamma-glutamyltransferase with severity of disease at diagnosis and prognosis of ovarian cancer

C Grimm, G Hofstetter, S Aust, I Mutz-Dehbalaie, M Bruch, G Heinze, J Rahhal-Schupp, A Reinthaller, N Concin, S Polterauer

British journal of Cancer (Nature) Austria, USA, 16 July 2013


Key words:Ovarian cancer, Prognostic markers

High resolution MRI for non-invasive mouse lymph node mapping

Zhuoli Zhang , Daniel Procissi, Weiguo Li, Dong-Hyun Kim, Kangan Li, Guohong Han, Yi Huan, Andrew C. Larson

Journal of Immunological Methods (Elsevier) USA, China, 11 July 2013


Key words:Mouse, Lymph node, Lymphatic drainage, India ink, Magnetic resonance imaging

A phase I trial of aminolevulinic acid-photodynamic therapy for treatment of oral leukoplakia

Stuart J. Wong, Bruce Campbell, Becky Massey, Denis P. Lynch, Ezra E.W. Cohen, Elizabeth Blair, Rebecca Selle, Julia Shklovskaya, Borko D. Jovanovic, Silvia Skripkauskas, Alexander Dew, Peter Kulesza, Vamsi Parimi, Raymond C. Bergan, e, Eva Szabo

Oral Oncology (Elsevier) USA, 08 July 2013


Key words:Leukoplakia, aminolevulinic acid, photodynamic therapy, phase I, laser

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