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Customer Publications (A total of 1249 papers published)

601
Exchange Protein Directly Activated by cAMP (EPAC) Regulates Neuronal Polarization through Rap1B

Pablo Muñoz-Llancao, Daniel R. Henríquez, Carlos Wilson, Felipe Bodaleo, Erik W. Boddeke, Frank Lezoualc'h, Martina Schmidt, Christian González-Billault

The Journal of Neuroscience (Society for Neuroscience) The Netherlands, Chile, France, 01 August 2015

Neuroscience

Key words:Exchange protein, cAMP, neuronal polarization, Rap1B

Organism: Rat

Cell Line: Hippocampal neurons 

602
Outcome in Heart Failure with Preserved Ejection Fraction: The Role of Myocardial Structure and Right Ventricular Performance

Georg Goliasch, Caroline Zotter-Tufaro, Stefan Aschauer, Franz Duca, Benedikt Koell, Andreas A. Kammerlander, Robin Ristl, Irene M. Lang, Gerald Maurer, Julia Mascherbauer, Diana Bonderman

PLOS ONE (PLOS) Austria, 30 July 2015

Cardiology

Key words:Extracellular matrix, biopsy, blood pressure, heart failure, hemodynamics, echocardiography, pulmonary arteries, ejection fraction

Organism: Human

Tissue: Heart

Pathological State: Heart Failure

603
Elevated S100A9 expression in tumor stroma functions as an early recurrence marker for early-stage oral cancer patients through increased tumor cell …

WY Fang, YW Chen, JR Hsiao, CS Liu, YZ Kuo, YC Wang, KC Chang, ST Tsai, MZ Chang, SH Lin, LW Wu

Oncotarget (NCBI) Taiwan, 22 July 2015

Oncology

Key words:S100A9, oral cancer, recurrence, IL-6, macrophages

Organism: Human

Tissue: Skin

Pathological State: Cancer

604
Development of Blood and Lymphatic Endothelial Cells in Embryonic and Fetal Human Skin

Schuster C, Mildner M, Botta A, Nemec L, Rogojanu R, Beer L, Fiala C, Eppel W, Bauer W, Petzelbauer P, Elbe-Bürger A

American Journal of Pathology (Elsevier) Austria, 16 July 2015

Pathology

Key words:Blood, lymphatic endothelial cells, embryonic, fetal human skin

Organism: Human

Tissue: Skin

605
POLE Proofreading Mutations Elicit an Antitumor Immune Response in Endometrial Cancer

Inge C. van Gool, Florine A. Eggink, Luke Freeman-Mills, Ellen Stelloo, Emanuele Marchi, Marco de Bruyn, Claire Palles, Remi A. Nout, Cor D. de Kroon, Elisabeth M. Osse, Paul Klenerman, Carien L. Creutzberg, Ian P.M. Tomlinson, Vincent T.H.B.M. Smit, Hans

Clinical Cancer Research (AACR) The Netherlands, UK, 15 July 2015

Oncology

Key words:Pole proofreading mutation, antitumor, immune response, endometrial cancer

Organism: Human

Tissue: Endometrium

Pathological State: Cancer

606
Langerhans Cells Maintain Local Tissue Tolerance in a Model of Systemic Autoimmune Disease

Jennifer K. King, Rachael L. Philips, Anna U. Eriksson, Peter J. Kim, Ramesh C. Halder, Delphine J. Lee, Ram Raj Singh

The Journal of Immunology (The Journal of Immunology) USA, 15 July 2015

Immunology

Key words:Lupus, langerhans cells

Organism: Mouse

Tissue: Skin

607
miR-135b- and miR-146b-dependent silencing of calcium-sensing receptor expression in colorectal tumors

Irfete S. Fetahu, Samawansha Tennakoon, Kate E. Lines, Charlotte Gröschel, Abhishek Aggarwal, Ildiko Mesteri, Sabina Baumgartner-Parzer, Robert M. Mader, Rajesh V. Thakker, Eniko Kállay

International Journal of Cancer (Wiley) Austria, UK, 14 July 2015

Oncology

Key words:Calcium-sensing receptor, microRNAs, colorectal cancer, miR-135b, miR-146b

Organism: Human

Pathological State: Cancer

Cell Line: Caco‐2 cells

608
mi R‐135b‐and mi R‐146b‐dependent silencing of calcium‐sensing receptor expression in colorectal tumors

Irfete S. Fetahu, Samawansha Tennakoon, Kate E. Lines, Charlotte Gröschel, Abhishek Aggarwal, Ildiko Mesteri, Sabina Baumgartner‐Parzer, Robert M. Mader, Rajesh V. Thakker , Enikő Kállay

International Journal of Cancer (Wiley) Austria, UK, 14 July 2015

Oncology

Key words:calcium‐sensing receptor, microRNAs, colorectal cancer, miR‐135b, miR‐146b

Organism: Human

Pathological State: Cancer

Cell Line: Caco2 and HT29 cells

609
Tumor dosimetry for I-131 trastuzumab therapy in a Her2+ NCI N87 xenograft mouse model using the Siemens SYMBIA E gamma camera with a pinhole collimator

Young Sub Lee, Jin Su Kim, Kyung Deuk Cho, Joo Hyun Kang, Sang Moo Lim

Journal of Instrumentation (IOP Publishing) South Korea, 06 July 2015

Oncology

Key words:Tumor dosimetry, xenograft mouse model, gamma camera, Siemens

Organism: Mouse

Pathological State: Cancer

Cell Line: Her2 Cells

610
Male-Specific Alleviation of Iron-Induced Striatal Injury by Inhibition of Autophagy

Li-Fang Wang, Kazunari K. Yokoyama, Tzu-Yin Chen, Hsiu-Wen Hsiao, Pei-Chi Chiang, Ya-Ching Hsieh, Steven Lo, Chin Hsu

PLOS ONE (PLOS) Taiwan, USA, 06 July 2015

Neuroscience

Key words:Autophagic cell death, neurons, neostriatum, neuronal tuning, histology, DNA fragmentation, mice, ovariectomy

Organism: Mouse

Tissue: Brain

Pathological State: Stratial Injury

611
miR-22 and miR-29a are members of the androgen receptor cistrome modulating LAMC1 and Mcl-1 in prostate cancer

Lorenza Pasqualini, Huajie Bu, Martin Puhr, Narisu Narisu, Johannes Rainer, Bettina Schlick, Georg Schäfer, Mihaela Angelova, Zlatko Trajanoski, Stefan T. Börno, Michal R. Schweiger, Christian Fuchsberger, Helmut Klocker

Molecular Endocrinology (Oxford Journals) Austria, USA, Italy, Germany, 01 July 2015

Endocrinology, Oncology

Key words:miR-22 , miR-29a ,Androgen Receptor Cistrome, LAMC1, Mcl-1, Prostate Cancer

Organism: Human

Tissue: Prostate

Pathological State: Cancer

612
Noncanonical Effects of IRF9 in Intestinal Inflammation: More than Type I and Type III Interferons

Isabella Rauch, Felix Rosebrock, Eva Hainzl, Susanne Heider, Andrea Majoros, Sebastian Wienerroither, Birgit Strobl, Silvia Stockinger, Lukas Kenner, Mathias Müller, Thomas Decker

Mollecular and Cellular Biology (ASM) Austria, 01 July 2015

Immunology

Key words:IRF9, intestinal inflammation, interferons

Organism: Mouse

Tissue: Colon

Pathological State: Colitis

613
Membrane-bound Klotho is not expressed endogenously in healthy or uraemic human vascular tissue

Rik Mencke, Geert Harms, Katarina Mirkovic, Joyce Struik, Joris Van Ark, Ellen Van Loon, Melissa Verkaik, Martin H. De Borst, Clark J. Zeebregts, Joost G. Hoenderop, Marc G. Vervloet, Jan-Luuk Hillebrands

Cardiovascular Research (Oxford University Press) The Netherlands, 01 July 2015

Cardiology

Key words:Membrane-bound Klotho, uraemic human vascular tissue

Organism: Human

Tissue: Kidney, Blood Vessels

614
T-cell Expression of IL10 Is Essential for Tumor Immune Surveillance in the Small Intestine

Kristen L. Dennis, Abdulrahman Saadalla, Nichole R. Blatner, Shuya Wang, Vysak Venkateswaran, Fotini Gounari, Hilde Cheroutre, Casey T. Weaver, Axel Roers, Nejat K. Egilmez, Khashayarsha Khazaie

Cancer Immunology Research (AACR) USA, Germany, 01 July 2015

Oncology

Key words:T -cell, IL10, tumor immune surveillance, small intestine

Organism: Mouse

Tissue: Small Intestine

615
Lanreotide-conjugated PEG-DSPE micelles: an efficient nanocarrier targeting to somatostatin receptor positive tumors

Nan Zheng, Wenbing Dai, Hua Zhang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Kun Wang, Jian Lia, Qiang Zhang

Journal of Drug Targeting (Taylor & Francis) China, 24 June 2015

Oncology

Key words:Lanreotide, over-express somatostatin receptor 2, 2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy (poly-(ethylene glycol))-2000]

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

616
Precision-cut kidney slices (PCKS) to study development of renal fibrosis and efficacy of drug targeting ex vivo

Fariba Poosti, Bao Tung Pham, Dorenda Oosterhuis, Klaas Poelstra, Harry van Goor, Peter Olinga, Jan-Luuk Hillebrands

Disease Models & Mechanisms (The Company of Biologists) The Netherlands, 24 June 2015

Nephrology

Key words:Drug targeting, Fibrosis, Kidney, Tissue slices

Organism: Mouse

Tissue: Kidney

Pathological State: Fibrosis

617
Memantine attenuates delayed vasospasm after experimental subarachnoid hemorrhage via modulating endothelial nitric oxide synthase

CY Huang, LC Wang, YS Shan, CH Pan, KJ Tsai

International Journal of Molecular Sciences (MDPI) Taiwan, 23 June 2015

Neuroscience

Key words:memantine; nitric oxide synthase; subarachnoid hemorrhage; vasospasm

Organism: Rat

Tissue: Brain

Pathological State: Vasospasm

618
STAT3 regulated ARF expression suppresses prostate cancer metastasis

Jan Pencik, Michaela Schlederer, Wolfgang Gruber, Christine Unger, Steven M. Walker, Athena Chalaris, Isabelle J. Marié, Melanie R. Hassler, Tahereh Javaheri, Osman Aksoy, Jaine K. Blayney, Nicole Prutsch, Anna Skucha, Merima Herac, Oliver H. Krämer, Pete

Nature Communications (Nature) Austria, UK, Germany, USA, Italy, Sweden, 22 June 2015

Oncology

Key words:STAT3 and p14ARF expression, PI3K–AKT–mTOR signalling pathway, ARF–Mdm2–p53 tumour suppressor axis

Organism: Mouse

Tissue: Xenograft Tumor, Colon

Pathological State: Cancer

619
The Role of ExoS in Dissemination of Pseudomonas aeruginosa during Pneumonia

Stephanie M. Rangel, Maureen H. Diaz, Claire A. Knoten, Angelica Zhang, Alan R. Hauser

Plos Pathogens (PLOS) USA, 19 June 2015

Pulmonology

Key words:Pneumocytes, pneumonia, bacterial pathogens, pseudomonas aeruginosa, pulmonary imaging, cell staining, phagocytes, blood

Organism: Mouse

Tissue: Lung

Pathological State: Pneumonia

620
Endothelial-to-mesenchymal transition contributes to fibro-proliferative vascular disease and is modulated by fluid shear stress

Jan-Renier A.J. Moonen, Ee Soo Lee, Marc Schmidt, Monika Maleszewska, Jasper A. Koerts, Linda A. Brouwer, Theo G. Van Kooten, Marja J.A. Van Luyn, Clark J. Zeebregts, Guido Krenning, Martin C. Harmsen

Cardiovascular Research (Oxford University Press) The Netherlands, Germany, 17 June 2015

Cardiology

Key words:LRRFIP1, EMT, Wnt/β-catenin signaling, β-catenin destruction complex, Reverse EMT

Organism: Human

Cell Line: HUVECs (Human umbilical vein endothelial cells)

621
Left Shift 1+ flag for the detection of band neutrophils: interlaboratory variations and recommendations for the routine laboratory

F. WEERKAMP, P. H. TAAL, B. A. De BOER and ON BEHALF OF THE ADdifVIA WORKING GROUP

International Journal of Laboratory Hematology (Wiley) The Netherlands, 16 June 2015

Hematology

Key words:Differential leukocyte count, left shift flag, band neutrophils, routine laboratory

Organism: Human

Cell Line: Blood

622
Image analysis for accurately counting CD4+ and CD8+ T cells in human tissue

Kurt Diema, Amalia Magaret, Alexis Klock, Lei Jina, Jia Zhu, Lawrence Corey

Journal of Virological Methods (Elsevier) USA, 12 June 2015

Virology

Key words:Cell counting, immunohistochemistry (IHC), software cell counting, HSV-2, cellProfiler

Organism: Human

Tissue: Penis

Pathological State: Virus Infection

623
Sorafenib and its derivative SC-1 exhibit antifibrotic effects through signal transducer and activator of transcription 3 inhibition

Tung-Hung Su, Chung-Wai Shiau, Ping Jao, Chen-Hua Liu, Chun-Jen Liu, Wei-Tien Tai, Yung-Ming Jeng, Hung-Chih Yang, Tai-Chung Tseng, Hsiang-Po Huang, Huei-Ru Cheng, Pei-Jer Chen, Kuen-Feng Chen, Jia-Horng Kao, Ding-Shinn Chen

PNAS (PNAS) Taiwan, 09 June 2015

Cell Biology

Key words:Hepatic stellate, cell STAT3 SHP-1, hepatitis B, liver fibrosis

624
298 MAST CELLS ARE ABUNDANT IN CUTANEOUS T‐CELL LYMPHOMAS AND CORRELATE WITH DISEASE STAGE

P. Gorniak, B. Budziszewska, B. Pula, M. Wasylecka, K. Borg, G. Nowak, H. Makuch - Lasica, E. Lech - Maranda, K. Warzocha, P. Juszczynski

Hematological Oncology (Wiley) Poland, 09 June 2015

Oncology

Key words:Cerebral ischemia–reperfusion injury, oxidative stress, apoptosis, superoxide, NADPH oxidase

Organism: Human

Tissue: Lymphoid Tissue

625
CD47 blockade inhibits tumor progression human osteosarcoma in xenograft models

JF Xu, XH Pan, SJ Zhang, C Zhao, BS Qiu, HF Gu, JF Hong, L Cao, Y Chen, B Xia, Q Bi, YP Wang

Oncotarget (NCBI) China, 08 June 2015

Oncology

Key words:osteosarcoma, CD47, antibody, immunotherapy

Organism: Mouse

Tissue: Lung, Xenograft Tumor

Pathological State: Cancer

626
ERG Activates the YAP1 Transcriptional Program and Induces the Development of Age-Related Prostate Tumors

Liem T. Nguyen, Maria S. Tretiakova, Mark R. Silvis, Jared Lucas, Olga Klezovitch, Ilsa Coleman, Hamid Bolouri, Vassily I. Kutyavin, Colm Morrissey, Lawrence D. True, Peter S. Nelson, Valeri Vasioukhin

Cancer Cell (Elsevier) USA, 08 June 2015

Oncology

Key words:Prostate cancer, actin cytoskeleton

Organism: Human

Tissue: Prostate

Pathological State: Cancer

627
The Dishevelled-binding protein CXXC5 negatively regulates cutaneous wound healing

Soung-Hoon Lee, Mi-Yeon Kim, Hyun-Yi Kim, Young-Mi Lee, Heesu Kim, Kyoung Ae Nam, Mi Ryung Roh, Do Sik Min, Kee Yang Chung, Kang-Yell Choi

The Journal of Experimental Medicine (The Rockefeller University Press) South Korea, 08 June 2015

Regenerative Medicine

Key words:Idiopathic pulmonary fibrosis, mesenchymal stem cell, mitochondrial membrane

Organism: Human

Tissue: Skin

Pathological State: Skin Wound

628
AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis

Jino Park, Michaela Schlederer, Martin Schreiber, Ryan Ice, Olaf Merkel, Martin Bilban, Sebastian Hofbauer, Soojin Kim, Joseph Addison, Jie Zou, Chunyan Ji, Silvia T. Bunting, Zhengqi Wang, Menachem Shoham, Gang Huang, Zsuzsanna Bago-Horvath, Laura F. Gib

Oncotarget (NCBI) USA, Austria, Germany, China, 07 June 2015

Oncology

Key words:AF1q, TCF7, CD44, Wnt, metastasis

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

629
Atopic donor status does not influence the uptake of the major grass pollen allergen, Phl p 5, by dendritic cells

Kazem Ashjaei, Dieter Palmberger, Merima Bublin, Erika Bajna, Heimo Breiteneder, Reingard Grabherr, Isabella Ellinger, Karin Hoffmann-Sommergruber

Journal of Immunological Methods (Elsevier) Austria, 05 June 2015

Immunology

Key words:Allergen; Endocytosis; Grass pollen; Monocyte derived dendritic cells; Phl p 5; SF-nsLTP

Organism: Human

Pathological State: Allergy

Cell Line: Blood

630
Synergistic antitumor effects of radiation and proteasome inhibitor treatment in pancreatic cancer through the induction of autophagy and the downregulation of TRAF6

Hui-Wen Chiu, Shu-Wen Lin, Li-Ching Lin, Yung-Ho Hsu, Yuh-Feng Lin, Sheng-Yow Ho, Yuan-Hua Wu, Ying-Jan Wang

Cancer Letters (Elsevier) Taiwan, 04 June 2015

Oncology

Key words:Radiation; Proteasome inhibitor; Autophagy; Endoplasmic reticulum stress; Pancreatic cancer

Organism: Mouse

Tissue: Xenograft Tumor, Pancreas

Pathological State: Cancer

631
Mast cell-macrophage dynamics in modulation of dengue virus infection in skin

Ya-Ting Chu, Shu-Wen Wan, Robert Anderson, Yee-Shin Lin

Immunology (Wiley) Taiwan, Canada, 04 June 2015

Immunology

Key words:Dengue virus, KitW-sh/W-sh mice, macrophage, mast cell

Organism: Mouse

Tissue: Skin

Pathological State: Virus Infection

632
Silencing of LRRFIP1 reverses the epithelial–mesenchymal transition via inhibition of the Wnt/β-catenin signaling pathway

Daisuke Douchi, Hideo Ohtsuka, Kyohei Ariake, Kunihiro Masuda, Shuhei Kawasaki, Kei Kawaguchi, Koji Fukase, Masaya Oikawa, Fuyuhiko Motoi, Takeshi Naitoh, Yu Katayose, Shinichi Egawa, Michiaki Unno

Cancer Letters (Elsevier) Japan, 03 June 2015

Oncology

Key words:LRRFIP1; EMT; Wnt/β-catenin signaling; β-catenin destruction complex; Reverse EMT

Organism: Human

Tissue: Pancreas

Pathological State: Cancer

633
Clinically applicable magnetic-labeling of natural killer cells for MRI of transcatheter delivery to liver tumors: preclinical validation for clinical translation

Kangan Li, Andrew C Gordon, Linfeng Zheng, Weiguo Li, Yang Guo, Jing Sun, Guixiang Zhang, Guohong Han, Andrew C Larson, Zhuoli Zhang

Nanomedicine (Future Medicine) China, USA, 01 June 2015

Nanomedicine

Key words:Intraportal vein, heparin-protamine-ferumoxytol, HPF-labeled NK cells

Organism: Rat

Tissue: Xenograft Tumor, Liver

Pathological State: Cancer

634
Prognostic Significance and Determinants of the 6-Min Walk Test in Patients With Heart Failure and Preserved Ejection Fraction

Caroline Zotter-Tufaro, Julia Mascherbaue, Franz Duca, Benedikt Koell, Stefan Aschaue, Andreas A. Kammerlande, Adelheid Panzenboeck, Roela Sadushi-Kolici, Christine Bangert, Daniela Laimer, Robin Ristl, Irene M. Lang, Diana Bonderman

JACC: Heart Failure (Elsevier) Austria, 01 June 2015

Cardiology

Key words:cardiac catheterization; exercise test; extracellular matrix; pulmonary circulation

Organism: Human

Tissue: Heart

Pathological State: Fibrosis

635
Mastocytosis: the new differential diagnosis of CD30-positive neoplasms

Irina Maric, Katherine R. Calvoa

Leukemia & Lymphoma (Taylor & Francis) USA, 01 June 2015

Oncology

Key words:Mastocytosis disease

636
Paracrine factors of human amniotic fluid-derived mesenchymal stem cells show strong anti-fibrotic properties by inhibiting myofibroblast differentiation and …

MM Mia, RA Bank

Journal of Stem Cell Research & Therapy (OMICS) The Netherlands, 21 May 2015

Stem Cell Research

Key words:Fibrosis; Fibroblasts; Myofibroblasts; TGFβ1; Mesenchymal stem cells; Extracellular matrix

Organism: Human

Cell Line: adipose tissue derived stem cells

637
Suppression of NADPH oxidase- and mitochondrion-derived superoxide by Notoginsenoside R1 protects against cerebral ischemia–reperfusion injury through estrogen receptor-dependent activation of Akt/Nrf2 pathways

X. Meng, M. Wang, X. Wang, G. Sun, J. Ye, H. Xu, X. Sun

Free Radical Research (Taylor & Francis) China, 20 May 2015

Neuroscience

Key words:Cerebral ischemia–reperfusion injury, oxidative stress, apoptosis, superoxide, NADPH oxidase

Organism: Rat

Tissue: Brain

Pathological State: Cerebral Ischemia

638
Hypoxia-preconditioned mesenchymal stem cells attenuate bleomycin-induced pulmonary fibrosis

Ying-Wei Lan, Kong-Bung Choo, Chuan-Mu Chen, Tsai-Hsien Hung, Young-Bin Chen, Chung-Hsing Hsieh, Han-Pin Kuo, Kowit-Yu Chong

Stem Cell Research and Therapy (Springer) China, Malaysia, 20 May 2015

Stem Cell Research

Key words:Bleomycin, diopathic pulmonary fibrosis, hypoxia-inducible factor, hepatocyte growth factor, connective tissue growth factor

Organism: Mouse

Tissue: Lung

Pathological State: Fibrosis

639
Texture analysis of 125I-A5B7 anti-CEA antibody SPECT differentiates metastatic colorectal cancer model phenotypes and anti-vascular therapy response

V Rajkumar, V Goh, M Siddique, M Robson, G Boxer, RB Pedley, GJR Cook

British Journal of Cancer (Wiley) UK, 19 May 2015

Oncology

Key words:Cancer models, Colorectal cancer Computed tomography Tumour heterogeneity

Organism: Mouse

Tissue: Liver

Pathological State: Cancer

640
Intracellular calcium levels as screening tool for nanoparticle toxicity

Claudia Meindl, Tatjana Kueznik, Martina Bösch, Eva Roblegg, Eleonore Fröhlich

Journal of Applied Toxicology (Wiley) Austria, 14 May 2015

Toxicology

Key words:Nanoparticles, cytotoxicity, apoptosis, lysosomes, calcium imaging

Organism: Human

Cell Line: EAhy926 cells (Human endothelial cell line)

641
Expression of Interferon γ by Decidual Cells and Natural Killer Cells at the Human Implantation Site

Chie-Pein Chen,Longzhu Piao, Xilin Chen, Jianhua Yu, Rachel Masch, Frederick Schatz, Charles J. Lockwood, S. Joseph Huang

Reproductive Sciences (SAGE Journals) Taiwan, USA, 11 May 2015

Reproductive Medicine

Key words:Interferon γ, NK cells, decidual cells

Organism: Human

Tissue: Endometrium

642
The systemic multiplication of Gallibacterium anatis in experimentally infected chickens is promoted by immunosuppressive drugs which have a less specific effect on the depletion of leukocytes

Surya Paudel, Claudia Hess, Patricia Wernsdorf, Tobias Käser, Sarah Meitz, Erika Jensen-Jarolim, Michael Hess, Dieter Liebhart

Veterinary Immunology and Immunopathology (Elsevier) Austria, 08 May 2015

Immunology

Key words:Gallibacterium anatis, chickensc, leukocyte quantification, non-selective immunosuppression

Organism: Chicken

Tissue: Spleen

Pathological State: Bacterial Infection

643
K-Ras stabilization by estrogen via PKCδ is involved in endometrial tumorigenesis

KH Koo, WJ Jeong, YH Cho, JC Park, DS Min, KY Choi

Oncotarget (NCBI) South Korea, 08 May 2015

Oncology

Key words:endometrial cancer, estrogen, tumorigenesis, K-Ras, PKCδ

Organism: Human

Tissue: Endometrium

Pathological State: Cancer

644
siRNA-based spherical nucleic acids reverse impaired wound healing in diabetic mice by ganglioside GM3 synthase knockdown

Pratik S. Randeria, Mark A. Seeger, Xiao-Qi Wang, Heather Wilson, Desmond Shipp, Chad A. Mirkin, Amy S. Paller

PNAS (PNAS) USA, 05 May 2015

Dermatology

Key words:SNA, nanoparticle, siRNA, GM3 synthase, diabetic wound healing

Organism: Mouse

Tissue: Adipose Tissue, Muscle

Pathological State: Obesity, Diabetes

645
CCL7 contributes to the TNF-alpha-dependent inflammation of lesional psoriatic skin

Patrick M. Brunner, Elisabeth Glitzner, Baerbel Reininger, Irene Klein, Georg Stary, Michael Mildner, Pavel Uhrin, Maria Sibilia, Georg Stingl

Experimental Dermatology (Wiley) Austria, 04 May 2015

Dermatology

Key words:CCL7, chemokines, myeloid cells, psoriasis, TNF-α

Organism: Human

Tissue: Skin

Pathological State: Psoriasis

646
Effect of Sodium-Glucose Cotransport Inhibition on Polycystic Kidney Disease Progression in PCK Rats

Sarika Kapoor, Daniel Rodriguez, Meliana Riwanto, Ilka Edenhofer, Stephan Segerer, Katharyn Mitchell, Rudolf P. Wüthrich

PLOS ONE (PLOS) Switzerland, 30 April 2015

Nephrology

Key words:sodium-glucose-cotransporter-2 (SGLT2), polycystic kidney disease, aquaretic drug tolvaptan

Organism: Rat

Tissue: Kidney

Pathological State: Polycystic Kidney Disease

647
Frontal cortex and hippocampus neurotransmitter receptor complex level parallels spatial memory performance in the radial arm maze

Bharanidharan Shanmugasundaram, Ajinkya Sase, András G. Miklosi, Fernando J. Sialana, Saraswathi Subramaniyan, Yogesh D. Aher, Marion Gröger, Harald Höger, Keiryn L. Bennett, Gert Lubec

Behavioural Brain Research (Elsevier) Austria, 28 April 2015

Neuroscience

Key words:Radial arm maze; Neurotransmitter receptor complex; Blue native PAGE; Spatial memory; D1-GluN1 complex

Organism: Rat

Tissue: Brain

648
Oncogenic role of miR-155 in anaplastic large cell lymphoma lacking the t(2;5) translocation

Olaf Merkel, Frank Hamacher, Robert Griessl, Lisa Grabner, Ana-Iris Schiefer, Nicole Prutsch, Constance Baer, Gerda Egger, Michaela Schlederer, Peter William Krenn, Tanja Nicole Hartmann, Ingrid Simonitsch-Klupp, Christoph Plass, Philipp Bernhard Staber,

Journal of Pathology (Wiley) Germany, Austria, UK, 27 April 2015

Oncology

Key words:miR-155, ALCL, ALK kinase, cytokines, IL-21, IL-22, IL-10

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

649
Enhancer of zeste homolog-2 (EZH2) methyltransferase regulates transgelin/smooth muscle-22α expression in endothelial cells in response to interleukin-1β and transforming growth factor-β2

Monika Maleszewska, Rutger A.F. Gjaltema, Guido Krenning, Martin C. Harmsen

Cellular Signalling (Elsevier) The Netherlands, 24 April 2015

Cell Biology

Key words:Endothelial cell, EZH2; SM22α, inflammation, fibrosis, chromatin

Organism: Human

Cell Line: HUVECs (Human umbilical vein endothelial cells)

650
Deoxycholate bile acid directed synthesis of branched Au nanostructures for near infrared photothermal ablation

Dong-Hyun Kima, Andrew C. Larson

Biomaterials (Elsevier) USA, 17 April 2015

Nanomedicine

Key words:Gold nanoparticles, bile acid, green chemistry, photothermal treatment, nanomedicine

Organism: Mouse

Tissue: Xenograft Tumor, Pancreas

Pathological State: Cancer

651
A-kinase-anchoring proteins coordinate inflammatory responses to cigarette smoke in airway smooth muscle

Wilfred J. Poppinga, Irene H. Heijink, Laura J. Holtzer, Philipp Skroblin, Enno Klussmann, Andrew J. Halayko, Wim Timens, Harm Maarsingh, Martina Schmidt

American Journal of Physiology (Elsevier) The Netherlands, Germany, Canada, USA, 15 April 2015

Pulmonology

Key words:CX3CR1, cuprizone, demyelination, spectroscopy, MRI

Organism: Human

Tissue: Lung

Pathological State: Chronic Obstructive Pulmonary Disease

652
Cytotoxity of nanoparticles is influenced by size, proliferation and embryonic origin of the cells used for testing

Eleonore Fröhlich, Claudia Meindl, Eva Roblegg, Antonia Griesbacher, Thomas R. Pieber

Nanotoxicology (Taylor & Francis) Austria, 13 April 2015

Toxicology

Key words:Calcium-sensing receptor, tumor suppressor, colon Inflammation, cancer EMT, cancer stem cell, calcimimetic

Organism: Human

Cell Line: EAhy926 cells and U-937 cells

653
Der p2 internalization by epithelium synergistically augments toll-like receptor-mediated proinflammatory signaling

SC Yin, EC Liao, CL Chiu, CY Chang, JJ Tsai

Allergy, Asthma & Immunology Research (Kamje Press) Taiwan, 10 April 2015

Allergy

Key words:Internalization; Der p2; human airway epithelium; Toll-like receptor 2; inflammation; calcitriol

Organism: Human

Tissue: Nasal Mucosa

654
Papain Degrades Tight Junction Proteins of Human Keratinocytes In Vitro and Sensitizes C57BL/6 Mice via the Skin Independent of its Enzymatic Activity or TLR4 Activation

Caroline Stremnitzer, Krisztina Manzano-Szalai, Anna Willensdorfer, Philipp Starkl, Mario Pieper, Peter König, Michael Mildner, Erwin Tschachler, Ursula Reichart, Erika Jensen-Jarolim

Journal of Investigative Dermatology (Elsevier) Austria, Germany, 09 April 2015

Dermatology

Key words:Dermatophagoides pteronyssinus, transepidermal water loss, phosphate-buffered saline, Toll-like receptor 4

Organism: Mouse

Tissue: Skin

655
EBV Oncogene N-LMP1 Induces CD4 T Cell–Mediated Angiogenic Blockade in the Murine Tumor Model

The Journal of Immunology (The Journal of Immunology) China, 06 April 2015

Oncology

Key words:Antiangiogenic N-LMP1–specific T cell, Tumor single cells, In vivo angiogenesis assays

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

656
Chondroitin sulfate-polyethylenimine copolymer-coated superparamagnetic iron oxide nanoparticles as an efficient magneto-gene carrier for microRNA-encoding …

YL Lo, HL Chou, ZX Liao, SJ Huang, JH Ke, YS Liu, CC Chiu, LF Wang

Nanoscale (Royal Society of Chemistry) Taiwan, 01 April 2015

Nanomedicine

Key words:Magnetofection, MicroRNA, Glioblastoma, Gene delivery

Organism: Human

Pathological State: Cancer

Cell Line: U87 cells

657
Lung-specific loss of α3 laminin worsens bleomycin-induced pulmonary fibrosis

LI Morales-Nebreda, MR Rogel…

American Journal of Respiratory Cell and Molecular Biology (ATS Journals) USA, Mexico, 01 April 2015

Pulmonology

Key words:laminin; matrix; pulmonary fibrosis; development

Organism: Mouse

Tissue: Lung

Pathological State: Fibrosis

658
Molecular characterization of whole mount prostate specimens using 5-color fluorescence labeling, virtual slide technology and automated image analysis

Georg E. Steiner, Gwenaelle Gaillard, Karina Pfeil, Claudia Strele, Christine Linder, Vincent Laurain, Radu Rogojanu, Rupert C. Ecker, Katja Oesterreicher, Lukas Kenner, Johannes Schmid, Helmut Klocker

Cancer Research (AACR) Austria, 01 April 2015

Medical Image Analysis

Key words:Prostate tissue samples, tubular epithelial ducts, epithelial and non-epithelial cells

659
nk4a/Arf-Dependent Loss of Parietal Cells Induced by Oxidative Stress Promotes CD44-Dependent Gastric Tumorigenesis

Ryo Seishima, Takeyuki Wada, Kenji Tsuchihashi, Shogo Okazaki, Momoko Yoshikawa, Hiroko Oshima, Masanobu Oshima, Toshiro Sato, Hirotoshi Hasegawa, Yuko Kitagawa, James R. Goldenring, Hideyuki Saya, Osamu Nagano

Cancer Prevention Research (AACR) Japan, USA, 26 March 2015

Oncology

Key words:Spasmolytic polypeptide–expressing metaplasia, reactive oxygen species, parietal cells

Organism: Mouse

Tissue: Stomach

660
Trained immunity in newborn infants of HBV-infected mothers

Michelle Hong, Elena Sandalova, Diana Low, Adam J. Gehring, Stefania Fieni, Barbara Amadei, Simonetta Urbani, Yap-Seng Chong, Ernesto Guccione, Antonio Bertoletti

Nature Communications (Nature) Singapore, Italy, UK, 25 March 2015

Immunology, Virology

Key words:Calcium-sensing receptor, colon cancer, calcium, vitamin D, chemoprevention, calcimimetic

Organism: Human

Pathological State: Virus Infection

Cell Line: CD2- cells (non-T non-NK cells)

661
Low-dose irradiation affects expression of inflammatory markers in the heart of ApoE-/-mice

Daniel Mathias, Ronald E. J. Mitchel, Mirela Barclay, Heather Wyatt, Michelle Bugden, Nicholas D. Priest, Stewart C. Whitman †, Markus Scholz, Guido Hildebrandt, Manja Kamprad, Annegret Glasow

Plos One (PLOS) Germany, Canada, 23 March 2015

Cardiology

Key words:Collagens, Dosimetry, Inflammation ,Fibrinogen ,Blood plasma ,Heart ,White blood cells ,Endothelial cells

Organism: Mouse

Tissue: Heart

662
Reproductive Sciences

Reproductive Sciences (SAGE Journals) , 22 March 2015

Reproductive Medicine

663
CD20+ T cells have a predominantly Tc1 effector memory phenotype and are expanded in the ascites of patients with ovarian cancer

Marco de Bruyn, Valerie R Wiersma, Maartje C A Wouters, Douwe F Samplonius, Harry G Klip, Wijnand Helfrich, Hans W Nijman, Paul Eggletonc, Edwin Bremer

OncoImmunology (Taylor & Francis) The Netherlands, UK, Canada, 19 March 2015

Immunology

Key words:Ascites, cancer immunology, CD20, ovarian cancer, trogocytosis, APC, Antigen-Presenting Cell, CTL, Cytotoxic T Lymphocyte, FSC, Forward Scatter, OC, Ovarian Cancer, PBMC, Peripheral Blood Mononuclear Cell, SCC, Side Scatter, TC, Cytotoxic T cell, TCM, Cen

Organism: Human

Tissue: Tonsil, Ovaries

Pathological State: Cancer

664
Cuprizone-induced demyelination and demyelination-associated inflammation result in different proton magnetic resonance metabolite spectra

Jelle Praet, Jasmien Orije, Firat Kara, Caroline Guglielmetti, Eva Santermans, Jasmijn Daans, Niel Hens, Marleen Verhoye, Zwi Berneman, Peter Ponsaerts, Annemie Van der Linden

NMR in Biomedicine (Wiley) Belgium, 19 March 2015

Oncology

Key words:GDF10/BMP3b, TGFBR3, oral cancer, prognostic marker, EMT, chemotherapy resistance

Organism: Mouse

Tissue: Brain

Pathological State: Demyelination

665
Tissue Microarrays for Translational Research

Ronald Simon, Martina Mirlacher

Microarrays in Diagnostics and Biomarker Development (Springer) Germany, 19 March 2015

Biological Methods

Key words:Tissue microarray,

666
MAP4K4 regulates integrin-FERM binding to control endothelial cell motility

Philip Vitorino, Stacey Yeung, Ailey Crow, Jesse Bakke, Tanya Smyczek, Kristina West, Erin McNamara, Jeffrey Eastham-Anderson, Stephen Gould, Seth F. Harris, Chudi Ndubaku & Weilan Ye

Nature (Nature) USA, 18 March 2015

Cell Biology

Key words:Focal adhesion

Organism: Mouse

Pathological State: Cancer

667
The calcium-sensing receptor suppresses epithelial-to-mesenchymal transition and stem cell- like phenotype in the colon

Abhishek Aggarwal, Maximilian Prinz-Wohlgenannt, Charlotte Gröschel, Samawansha Tennakoon, Anastasia Meshcheryakova, Wenhan Chang, Edward M Brown, Diana Mechtcheriakova, Enikö Kállay

Molecular Cancer (Springer) Austria, USA, 18 March 2015

Oncology

Key words:EVI1, MS4A3, transcriptional repression, myeloid leukemia, tumor growth

Organism: Mouse, Human

Tissue: Colon

Pathological State: Cancer

Cell Line: HT29 cells (colon cancer cell line)

668
CARDIAC MAGNETIC RESONANCE T1 MAPPING FOR QUANTIFICATION OF EXTRACELLULAR MATRIX - VALIDATION BY MYOCARDIAL BIOPSY

Andreas Anselm Kammerlander, Caroline Tufaro, Alina Bachmann, Beatrice Marzluf, Stefan Aschauer, Andreas Greiser, Diana Bonderman, Julia Mascherbauer

Journal of the American College of Cardiology (Elsevier) Austria, 16 March 2015

Cardiology

Key words:Diffuse myocardial fibrosis, extracellular matrix expansion, cardiac magnetic resonance

Organism: Human

Tissue: Heart

Pathological State: Heart Failure

669
The Upregulation of LAG-3 on T Cells Defines a Subpopulation with Functional Exhaustion and Correlates with Disease Progression in HIV-Infected Subjects

The Journal of Immunology (The American Association of Immunologists) China, 16 March 2015

Immunology, Virology

Key words:Plasmodium infection, virus–specific CD8+ T cells, human embryonic kidney cells

Organism: Human

Tissue: Lymphoid Tissue

Pathological State: Virus Infection

670
Effect of 1,25-dihydroxyvitamin D3 on the Wnt pathway in non-malignant colonic cells

Charlotte Gröschel, Abhishek Aggarwal, Samawansha Tennakoon, Julia Höbaus, Maximilian Prinz-Wohlgenannt, Brigitte Marian, Petra Heffeter, Walter Berger, Eniko Kállay

The Journal of Steroid Biochemistry and Molecular Biology (Elsevier) Austria, 14 March 2015

Oncology

Key words:1,25-Dihydroxyvitamin D3, colorectal cancer, chemoprevention, wnt pathway, LGR5

Organism: Human

Tissue: Colon

Pathological State: Cancer

671
Vimentin regulates activation of the NLRP3 inflammasome

Gimena dos Santos, Micah R. Rogel, Margaret A. Baker, James R. Troken, Daniela Urich, Luisa Morales-Nebreda, Joseph A. Sennello, Mikhail A. Kutuzov, Albert Sitikov, Jennifer M. Davis, Anna P. Lam, Paul Cheresh, David Kamp, Dale K. Shumaker, G. R. Scott Bu

Nature Communications (Nature) USA, 12 March 2015

Cell Biology

Key words:Cytoskeletal proteins, Inflammasome, NOD-like receptors, Respiratory tract diseases

Organism: Mouse

Tissue: Heart, Lung

672
Nitric Oxide Prevents Alveolar Senescence and Emphysema in a Mouse Model

Amanda E. Boe, Mesut Eren, Luisa Morales-Nebreda, Sheila B. Murphy, G. R. Scott Budinger, Gökhan M. Mutlu, Toshio Miyata, Douglas E. Vaughan

PLOS ONE (PLOS) USA, Japan, 10 March 2015

Pulmonology

Key words:Nω-nitro-L-arginine methyl ester, alveolar tissue destruction, plasminogen activator inhibitor-1

Organism: Mouse

Tissue: Lung

Pathological State: Chronic Obstructive Pulmonary Disease

673
Clinical improvement in psoriasis with specific targeting of interleukin-23

Tamara Kopp, Elisabeth Riedl, Christine Bangert, Edward P. Bowman, Elli Greisenegger, Ann Horowitz, Harald Kittler, Wendy M. Blumenschein, Terrill K. McClanahan, Thomas Marbury, Claus Zachariae, Danlin Xu, Xiaoli Shirley Hou, Anish Mehta, Anthe S. Zandvli

Nature (Nature) Austria, USA, Denmark, 09 March 2015

Dermatology

Key words:Psoriasis, interleukin-23

674
Induction of c-Cbl contributes to anti-cancer effects of HDAC inhibitor in lung cancer

TT Wei, YC Lin, PH Lin, JY Shih, CW Chou, WJ Huang, YC Yang, PW Hsiao, CC Chen

Oncotarget (NCBI) Taiwan, 08 March 2015

Oncology

Key words:c-Cbl, EGFR, HDAC inhibitors, lung cancer

Organism: Mouse

Tissue: Lung

Pathological State: Cancer

675
Active vitamin D potentiates the anti-neoplastic effects of calcium in the colon: A cross talk through the calcium-sensing receptor

Abhishek Aggarwal, Julia Höbaus, Samawansha Tennakoon, Maximilian Prinz-Wohlgenannt, João Graça, Sally A. Price, Petra Heffeter, Walter Berger, Sabina Baumgartner-Parzer, Enikö Kállay

The Journal of Steroid Biochemistry and Molecular Biology (Elsevier) Austria, UK, 07 March 2015

Oncology

Key words:Calcium-sensing receptor, Colon cancer, Calcium, Vitamin D, Chemoprevention, Calcimimetic

Organism: Mouse

Tissue: Colon

676
Zileuton, 5-Lipoxygenase Inhibitor, Acts as a Chemopreventive Agent in Intestinal Polyposis, by Modulating Polyp and Systemic Inflammation

Elias Gounaris, Michael J. Heiferman, Jeffrey R. Heiferman, Manisha Shrivastav, Dominic Vitello, Nichole R. Blatner, Lawrence M. Knab, Joseph D. Phillips, Eric C. Cheon, Paul J. Grippo, Khashayarsha Khazaie, Hidayatullah G. Munshi, David J. Bentrem

PLOS ONE (PLOS) USA, 06 March 2015

Oncology

Key words:Calcium-sensing receptor, tumor suppressor, colorectal cancer, colon, calcium, calcimimetic, calcilytic

Organism: Mouse

Tissue: Small Intestine

Pathological State: Cancer

677
Disruption of ​STAT3 signalling promotes ​KRAS-induced lung tumorigenesis

Beatrice Grabner, Daniel Schramek, Kristina M. Mueller, Herwig P. Moll, Jasmin Svinka, Thomas Hoffmann, Eva Bauer, Leander Blaas, Natascha Hruschka, Katalin Zboray, Patricia Stiedl, Harini Nivarthi, Edith Bogner, Wolfgang Gruber, Thomas Mohr, Ralf Harun Z

Nature Communications (Nature) Austria, USA, Italy, Hungary, 03 March 2015

Oncology

Key words:Interleukin-6, oncostatin-M, epidermal growth factor, Lung cancer

Organism: Human

Tissue: Lung

Pathological State: Cancer

678
Comparative Proteomic Analysis Reveals Activation of Mucosal Innate Immune Signaling Pathways during Cholera

Crystal N. Ellis,Regina C. LaRocquea, Taher Uddin, Bryan Krastins, Leslie M. Mayo-Smith, David Sarracino, Elinor K. Karlsson, Atiqur Rahman, Tahmina Shirin, Taufiqur R. Bhuiyan, Fahima Chowdhury, Ashraful Islam Khan, Edward T. Ryan,, Stephen B. Calderwood

Infection and Immunity (ASM) USA, Bangladesh, 01 March 2015

Immunology

Key words:Tissue microarray, Tissue cores, Population studies, Virtual microscopy, Data exchange, Standards Validation studies, Quality assurance, Donor block, Recipient block, Multitumo,r Tissue microarray, Progression tissue microarray, Prognosis tissue microarra

Organism: Human

Tissue: Small Intestine

Pathological State: Bacterial Infection

679
Loss of GDF10/BMP3b as a prognostic marker collaborates with TGFBR3 to enhance chemotherapy resistance and epithelial-mesenchymal transition in oral squamous cell carcinoma

Chieh-Wen Cheng, Jenn-Ren Hsiao, Chi-Chen Fan, Yu-Kang Lo, Chi-Yuan Tzen, Li-Wha Wu, Wei-Yu Fang, Ann-Joy Cheng, Chung-Hsing Chen, I-Shou Chang, Shih Sheng Jiang, Jang-Yang Chang, Alan Yueh-Luen Lee

Molecular Carcinogenesis (Wiley) Taiwan, 01 March 2015

Oncology

Key words:Growth differentiation factor-10, transforming growth factor-β (TGF-β) superfamily, oral squamous cell carcinoma

Organism: Human

Tissue: Oral Mucosa

Pathological State: Cancer

680
EVI1 promotes tumor growth via transcriptional repression of MS4A3

Gerwin Heller, Anna Rommer, Katarina Steinleitner, Julia Etzler, Hubert Hackl, Petra Heffeter, Erwin Tomasich, Martin Filipits, Birgit Steinmetz, Thais Topakian, Simone Klingenbrunner, Barbara Ziegler, Andreas Spittler, Sabine Zöchbauer-Müller, Walter Ber

Journal of Hematology and Oncology (Springer) Austria, 01 March 2015

Oncology

Key words:EVI1, MS4A3, Transcriptional repression, Myeloid leukemia, Tumor growth

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

681
16 Dectin-2 is essentially involved in innate immune response of experimental arthritis

V Stögner, T Shvets, B Niederreiter, M Koenders, WB van den Berg, JS Smolen, K Redlich, S Hayer

Annals of the Rheumatic Diseases (BMJ) Austria, The Netherlands, 01 March 2015

Rheumatology

Key words:C-type lectin receptor Dectin-2, Toll-like receptors, myeloid cells

Organism: Mouse

Tissue: Blood

Pathological State: Rheumatoid Arthritis

682
Poly(lactide-co-glycolide) microspheres for MRI-monitored delivery of sorafenib in a rabbit VX2 model

Jeane Chena, Sarah B. White, Kathleen R. Harris, Weiguo Li, Jonathan W.T. Yap, Dong-Hyun Kim, Robert J. Lewandowski, Lonnie D. Shea, Andrew C. Larson

Biomaterials (Elsevier) USA, 25 February 2015

Nanomedicine

Key words:Sorafenib, hepatocellular carcinoma, poly(lactide-co-glycolide), magnetic resonance imaging

Organism: Rabbit

Tissue: Liver, Stomach, Lung

683
Regulatory T cell-deficient scurfy mice develop systemic autoimmune features resembling lupus-like disease

Eva N Hadaschik, Xiaoying Wei, Harald Leiss, Britta Heckmann, Birgit Niederreiter, Günter Steiner, Walter Ulrich, Alexander H Enk, Josef S Smolen, Georg H Stummvoll

Arthritis Research & Therapy (BioMed Central) Germany, China, Austria, 23 February 2015

Rheumatology

Key words:Systemic lupus erythematosus, severe interface dermatitis, arthritis, mesangioproliferative glomerulonephritis

Organism: Mouse

Tissue: Joint

Pathological State: Lupus

684
The calcium-sensing receptor: A promising target for prevention of colorectal cancer

Abhishek Aggarwal, Maximilian Prinz-Wohlgenannt, Samawansha Tennakoona, Julia Höbaus, Cedric Boudot, Romuald Mentaverri, Edward M. Brown, Sabina Baumgartner-Parzer, Enikö Kállay

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (Elsevier) Austria, France, USA, 18 February 2015

Oncology

Key words:Calcium-sensing receptor, tumor suppressor, colorectal cancer, colon, calcium, calcimimetic, calcilytic

Organism: Human

Pathological State: Cancer

Cell Line: Caco2-15 and HT29 cells

685
MRI visible drug eluting magnetic microspheres for transcatheter intra-arterial delivery to liver tumors

DH Kim, J Chen, RA Omary, AC Larson

Theranostics (NCBI) USA, 07 February 2015

Oncology, Nanomedicine

Key words:MRI, microspheres, liver tumors

Organism: Rat

Tissue: Liver

Pathological State: Cancer

686
Generation of an anti-EpCAM antibody and epigenetic regulation of EpCAM in colorectal cancer

Mei-Ying Liao, Mark Yen-Ping Kuo, Tung-Ying Lu, Yi-Ping Wang, Han-Chung Wu

International Journal of Oncology (Spandidos Publications) Taiwan, 05 February 2015

Oncology

Key words:epigenetic regulation, EpCAM, colorectal cancer

Organism: Human

Tissue: Colon

Pathological State: Cancer

687
Tissue Microarray

Myra L. Wilkerson, Stephen M. Hewitt

Handbook of Practical Immunohistochemistry (Springer) USA, 05 February 2015

Biological Methods

Key words:Tissue microarray, tissue cores, population studies, virtual microscopy, data exchange, standards, validation studies, quality assurance, donor block, recipient block, multitumor, tissue microarray, progression tissue microarray, prognosis tissue microarr

688
Extracellular matrix expansion by cardiac magnetic resonance T1 mapping- validation with myocardial biopsy

Andreas Kammerlander, Caroline Tufaro, Alina F Bachmann, Beatrice A Marzluf, Stefan Aschauer, Andreas Greiser, Diana Bonderman, Julia Mascherbauer

Journal of Cardiovascular Magnetic Resonance (Springer) Austria, Germany, 03 February 2015

Cardiology

Key words:Cardiology, angiology, imaging/radiology

Organism: Human

Tissue: Heart

Pathological State: Heart Failure

689
The expression of thymic stromal lymphopoietin in primary tumors of breast cancer is associated with prognosis

Yu H, Yang J, Li Y, Jiao S

Pub Med (Pub Med) China, 01 February 2015

Oncology

Key words:Rythymic stromal lymphopoietin, disease-free survival, Univariate LOG-RANK

Organism: Human

Tissue: Breast

Pathological State: Cancer

690
Distinct in vitro properties of embryonic and extraembryonic fibroblast-like cells are reflected in their in vivo behavior following grafting in the adult mouse brain

Costa R, Bergwerf I, Santermans E, De Vocht N, Praet J, Daans J, Le Blon D, Hoornaert C, Reekmans K, Hens N, Goossens H, Berneman Z, Parolini O, Alviano F, Ponsaerts P.

Cell Transplantation (SAGE Journals) Italy, 01 February 2015

Transplantation Medicine

Key words:Fetal membrane-derived stromal cells, Embryonic fibroblasts, Immunomodulation, Transplantation, Brain, Angiogenesis

Organism: Mouse

Tissue: Brain

691
The Major Birch Pollen Allergen Bet v 1 Induces Different Responses in Dendritic Cells of Birch Pollen Allergic and Healthy Individuals

Ursula Smole, Christian Radauer, Nina Lengger, Martin Svoboda, Neil Rigby, Merima Bublin, Sonja Gaier, Karin Hoffmann-Sommergruber, Erika Jensen-Jarolim, Diana Mechtcheriakova , Heimo Breiteneder

PLOS ONE (PLOS) USA, Austria, UK, 30 January 2015

Allergy

Key words:Allergens, cytokines, gene expression, pollen, immune response, fluorescence competition, monocytes, chemokines

Organism: Human

Pathological State: Allergy

Cell Line: iMoDCs ( immature monocyte-derived dendritic cells)

692
Biomarkers in Lung Diseaes: from Pathogenesis to Prediction to New Therapies: A-kinase-anchoring proteins coordinate inflammatory responses to cigarette …

Wilfred J. Poppinga, Irene H. Heijink, Laura J. Holtzer, Philipp Skroblin, Enno Klussmann, Andrew J. Halayko, Wim Timens, Harm Maarsingh, Martina Schmidt

American Journal of Physiology (American Physiological, Society) The Netherlands, Germany, Canada, USA, 30 January 2015

Pulmonology

Key words:Compartmentalization, A-kinase-anchoring protein, inflammation, cyclic AMP, chronic obstructive pulmonary disease

Organism: Human

Cell Line: Human bronchial ASM cells

693
Correlation of circular RNA abundance with proliferation–exemplified with colorectal and ovarian cancer, idiopathic lung fibrosis, and normal human tissues

Anna Bachmayr-Heyda, Agnes T. Reiner, Katharina Auer, Nyamdelger Sukhbaatar, Stefanie Aust, Thomas Bachleitner-Hofmann, Ildiko Mesteri, Thomas W. Grunt, Robert Zeillinger & Dietmar Pils

Scientific reports (Nature) Austria, 27 January 2015

Oncology

Key words:Cancer genetics, Epigenetics

Organism: Human

Tissue: Colon

Pathological State: Cancer

694
Mapping spatial heterogeneity in the tumor microenvironment: a new era for digital pathology

Andreas Heindl, Sidra Nawaz, Yinyin Yuan

Nature (Nature) UK, 19 January 2015

Oncology

Key words:Tumor, digital pathology, mapping, spatial heterogeneity

695
Loss of mitochondrial exo/endonuclease EXOG affects mitochondrial respiration and induces ROS-mediated cardiomyocyte hypertrophy

Wardit Tigchelaar, Hongjuan Yu, Anne Margreet de Jong, Wiek H. van Gilst, Pim van der Harst, B. Daan Westenbrink, Rudolf A. de Boer, Herman H. W. Silljé

Cell Physiology (APS Journals) The Netherlands, China, 15 January 2015

Cardiology

Key words:Cardiomyocytes, hypertrophy, mitochondria, mitochondrial respiration, ROS

Organism: Rat

Pathological State: Hypertrophy

Cell Line: NRVCs (neonatal rat ventricular cardiomyocytes)

696
Down-regulation of TIMP-1 inhibits cell migration, invasion, and metastatic colonization in lung adenocarcinoma

Ying-Hua Chang, Yi-Jen Chiu, Hung-Chi Cheng, Fang-Ju Liu, Wu-Wei Lai, Hsiao-Jen Chang, Pao-Chi Liao

Tumor Biology (Springer) Taiwan, USA, 13 January 2015

Oncology

Key words:TIMP-1, migration, invasion,metastatic colonization, pericellular fibronectin assembly, lung adenocarcinoma

Organism: Human

Tissue: Lung

Pathological State: Cancer

697
Localization of sunitinib, its metabolites and its target receptors in tumour-bearing mice: a MALDI-MS imaging study

S Torok, A Vegvari, M Rezeli, T E Fehniger, J Tovari, S Paku, V Laszlo, B Hegedus, A Rozsas, B Dome, G. Marko-Varga

British Journal of Pharmacology (Wiley) Hungary, Austria, Sweden, Japan, 12 January 2015

Pharmacology

Key words:C-26 adenocarcinoma cells, matrix-assisted laser desorption ionization MS imaging, VEGF receptor-2

Organism: Mouse

Tissue: Allograft Tumor, Colon

Pathological State: Cancer

698
Epitope topography controls bioactivity in supramolecular nanofibers

S Sur, F Tantakitti, JB Matson, SI Stupp

Biomaterials Science (Royal Society of Chemistry) USA, 09 January 2015

Nanomedicine

Key words:Epitope topography, bioactivity, nanofibers

Organism: Mouse

Cell Line: mouse embryonic fibroblasts

699
A multidisciplinary approach unravels early and persistent effects of X-ray exposure at the onset of prenatal neurogenesis

Tine Verreet, Roel Quintens, Debby Van Dam, Mieke Verslegers, Mirella Tanori, Arianna Casciati, Mieke Neefs, Liselotte Leysen, Arlette Michaux, Ann Janssen, Emiliano D’Agostino, Greetje Vande Velde, Sarah Baatout, Lieve Moons, Simonetta Pazzaglia, Anna Sa

Journal of Neurodevelopmental Disorders (Springer) Belgium, Italy, The Netherlands, 09 January 2015

Neuroscience

Key words:Apoptosis, Brain development, Cognitive dysfunction, MRI, Radiation

Organism: Mouse

Tissue: Brain

700
Relationship between Apoptosis Imaging and Radioiodine Therapy in Tumor Cells with Different Sodium Iodide Symporter Gene Expression

Kyung Oh Jung, Hyewon Youn, Young-Hwa Kim, Seunghoo Kim, Juri Na, Yong-Il Kim, Jin Woo Park, Keon Wook Kang, Dong Soo Lee, June-Key Chung

Molecular Imaging (SAGE Journals) South Korea, 01 January 2015

Oncology

Key words:Apoptosis Imaging, Radioiodine Therapy, Tumor Cells, Sodium Iodide Symporter

Organism: Human

Pathological State: Cancer

Cell Line: human colorectal adenocarcinoma cell line (HT29)

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