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Customer Publications (A total of 1287 papers published)

601
Cardioprotective Actions of TGFßRI Inhibition Through Stimulating Autocrine/Paracrine of Survivin and Inhibiting Wnt in Cardiac Progenitors

Yu-Sian Ho, Wan-Hsuan Tsai, Fen-Chiung Lin, Wei-Pang Huang, Lung-Chun Lin, Sean M. Wu, Yu-Ru Liu, Wen-Pin Chen

Stem Cells (Wiley) Taiwan, USA, 10 October 2015

Stem Cell Research

Key words:Nkx2.5, sca1, Birc5, survivin, MEK/ERK, Wnt3a

Organism: Mouse

Tissue: Heart

Pathological State: Fibrosis

602
YAP1 Is a Driver of Myofibroblast Differentiation in Normal and Diseased Fibroblasts

Bram Piersma, Saskia de Rond, Paul M.N. Werker, Stellar Boo, Boris Hinz, Marike M. van Beuge, Ruud A. Bank

The American Journal of Pathology (Elsevier) The Netherlands, Canada, 10 October 2015

Pathology

Key words:Myofibroblast, fibroblasts, YAP 1

Organism: Human

Pathological State: Dupuytren's Disease

Cell Line: Dermal fibroblasts

603
The pro-fibrotic properties of transforming growth factor on human fibroblasts are counteracted by caffeic acid by inhibiting myofibroblast formation and collagen synthesis

Masum M. Mia, Ruud A. Bank

Cell and Tissue Research (Springer) The Netherlands, 09 October 2015

Cell Biology

Key words:Fibrosis, collagen, myofibroblasts, caffeic acid, lysyl hydroxylase

Organism: Human

Cell Line: HDFa and HLFa Fibroblasts

604
Characterization of sulfur mustard resistant keratinocyte cell line HaCaT/SM

Wolf Markus, Siegert Markus, Rothmiller Simone, Scheithauer Nina, Strobelt Romano, Steinritz Dirk, Thiermann Horst, Schmidt Annette

Toxicology Letters (Elsevier) Germany, 09 October 2015

Toxicology

Key words:Sulfur mustard, resistance, keratinocytes

Organism: Human

Cell Line: HaCaTs (human keratinocyte cell line )

605
Synergy of endothelial and neural progenitor cells from adipose-derived stem cells to preserve neurovascular structures in rat hypoxic-ischemic brain injury

Yuan-Yu Hsueh, Ya-Ju Chang, Chia-Wei Huang, Fitri Handayani, Yi-Lun Chiang, Shih-Chen Fan, Chien-Jung Ho, Yu-Min Kuo, Shang-Hsun Yang, Yuh-Ling Chen, Sheng-Che Lin, Chao-Ching Huang and Chia-Ching Wu

Scientific Reports (Nature) Taiwan, 08 October 2015

Neuroscience

Key words:Neural progenitors, stem cells, brain injury

Organism: Rat

Tissue: Brain

Pathological State: Cerebral Ischemia

606
YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model

Tsion Zewdu Minas, Jenny Han, Tahereh Javaheri, Sung-Hyeok Hong, Michaela Schlederer, Yasemin Saygideğer-Kont, Haydar Çelik, Kristina M. Mueller, Idil Temel, Metin Özdemirli, Heinrich Kovar, Hayriye Verda Erkizan, Jeffrey Toretsky, Lukas Kenner, Richard Moriggl,and Aykut Üren

Oncotarget (Impact Journals) USA, Austria, 08 October 2015

Oncology

Key words:EWS-FLI1, ETS fusion proteins, YK-4-279, ewing sarcoma, erythoid leukemia

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

607
Sympathetic Neurotransmitters Modulate Osteoclastogenesis and Osteoclast Activity in the Context of Collagen-Induced Arthritis

Dominique Muschter, Nicole Schäfer, Hubert Stangl, Rainer H. Straub, Susanne Grässel

PLOS ONE (PLOS) Germany, 02 October 2015

Rheumatology

Key words:Osteoclasts, neurotransmitters, arthritis, macrophages, apoptosis, gene expression, adenylyl cyclase, immune receptors

Organism: Human

Pathological State: Cancer

Cell Line: SAOS2 cells (primary osteogenic sarcoma cells)

608
Intestinal Epithelial Cell Tyrosine Kinase 2 Transduces IL-22 Signals To Protect from Acute Colitis

Eva Hainzl, Silvia Stockinger, Isabella Rauch, Susanne Heider, David Berry, Caroline Lassni, Clarissa Schwab, Felix Rosebrock, Gabriel Milinovich, Michaela Schlederer, Michael Wagner, Christa Schleper, Alexander Loy, Tim Urich, Lukas Kenner, Xiaonan Han, Thomas Decker, Birgit Strobl, Mathias Müller

The Journal of Immunology (American Association of Immunologists) Austria, USA, 02 October 2015

Gastroenterology

Key words:Intestinal epithelial cell, acute colitis

Organism: Mouse

Tissue: Colon

Pathological State: Colitis

609
The decrease in histone methyltransferase EZH2 in response to fluid shear stress alters endothelial gene expression and promotes quiescence

Monika Maleszewska, Byambasuren Vanchin, Martin C. Harmsen, Guido Krenning

Angiogenesis (Springer) The Netherlands, Germany, 28 September 2015

Cell Biology

Key words:Endothelial cell, enhancer of zeste homolog-2 (EZH2), fluid shear stress (FSS), mechanotransduction, chromatin

Organism: Human

Cell Line: HUVECs (Human umbilical vein endothelial cells)

610
Putative Prostate Cancer Risk SNP in an AR Binding Site of the Melanophilin Gene Illustrates Enrichment of Risk SNPs in AR Target Sites

Huajie Bu, Narisu Narisu, Bettina Schlick, Johannes Rainer, Thomas Manke, Georg Schäfer, Lorenza Pasqualini, Peter Chines, Michal R. Schweiger, Christian Fuchsberger, Helmut Klocker

Human Mutation (Wiley) Austria, Germany, Italy, USA, 28 September 2015

Oncology

Key words:Prostate cancer, risk SNPs, androgen receptor, melanophilin, MLPH;androgen regulation, AR

Organism: Human

Tissue: Prostate

Pathological State: Cancer

611
A sunblock based on bioadhesive nanoparticles

Y Deng, A Ediriwickrema, F Yang, J Lewis, M Girardi…

British journal of Cancer (Nature) , 28 September 2015

612
Amelioration of Chemotherapy-Induced Intestinal Mucositis by Orally Administered Probiotics in a Mouse Model

Chun-Yan Yeung , Wai-Tao Chan , Chun-Bin Jiang, Mei-Lien Cheng, Chia-Yuan Liu, Szu-Wen Chang, Jen-Shiu Chiang Chiau, Hung-Chang Lee

PLOS ONE (PLOS) Taiwan, 25 September 2015

Oncology

Key words:Probiotics, gastrointestinal tract, diarrhea, mouse models, cytokines, jejunum, lactobacillus, cancer treatment

Organism: Mouse

Tissue: Small Intestine

Pathological State: Mucositis

613
The great escape: Pseudomonas breaks out of the lung

A Zhang, SM Rangel, AR Hauser

Microbial Cell (NCBI) USA, 23 September 2015

Microbiology

Key words:Pseudomonas aeruginosa, ExoS, pneumonia, dissemination

Organism: Mouse

Tissue: Lung

Pathological State: Bacterial Infection

614
Type 3 innate lymphoid cells maintain intestinal epithelial stem cells after tissue damage

Patricia Aparicio-Domingo, Monica Romera-Hernandez, Julien J. Karrich, Ferry Cornelissen, Natalie Papazian, Dicky J. Lindenbergh-Kortleve, James A. Butler, Louis Boon, Mark C. Coles, Janneke N. Samsom, Tom Cupedo

Journal of Experimental Medicine (Rockefeller University Press) The Netherlands, UK, 21 September 2015

Stem Cell Research

Key words:Type 3 innate lymphoid cells, intestinal epithelial stem cells, tissue damage

Organism: Mouse

Tissue: Small Intestine, Colon

615
Bone marrow micro-environmental CD4+ and CD8+ lymphocyte infiltration patterns define overall- and progression free survival in standard risk Multiple Myeloma – an analysis from the Austrian Myeloma Registry

Wolfgang Willenbacher, Ella Willenbacher, Claudia Zelle-Rieser, Rainer Biedermann, Roman Weger, Karin Jöhrer, Andrea Brunner

Leukemia and Lymphoma (Taylor and Francis) Austria, 19 September 2015

Oncology

Key words:Bone marrow, lymphocite infiltration, myeloma

Organism: Human

Tissue: Bone

Pathological State: Cancer

616
Quantitative functional MRI in a clinical orthotopic model of pancreatic cancer in immunocompetent Lewis rats

Zhuoli Zhang, Linfeng Zheng, Weiguo Li, Andrew C Gordon, Yi Huan, Junjie Shangguan, Daniel Procissi, David J Bentrem, Andrew C Larson

American Journal of Translational Research (e-Century Publishing Corporation) USA, China, 15 September 2015

Oncology

Key words:Magnetic resonance imaging, imaging biomarker, pancreatic cancer, immunocompetent Lewis rats

Organism: Rat

Tissue: Pancreas

Pathological State: Cancer

617
Nuclear HDAC6 inhibits invasion by suppressing NF-κB/MMP2 and is inversely correlated with metastasis of non-small cell lung cancer

CJ Yang, YP Liu, HY Dai, YL Shiue, CJ Tsai…

Oncotarget (Impact Journals) Taiwan, 15 September 2015

Oncology

Key words:HDAC6, NF-κB, MMP2, metastasis, lung cancer

Organism: Human

Tissue: Lung

Pathological State: Cancer

618
Sulfur and nitrogen mustards induce characteristic poly(ADP-ribosyl)ation responses in HaCaT keratinocytes with distinctive cellular consequences

Aswin Mangerich, Malgorzata Debiak, Matthias Birtel, Viviane Ponath, Frank Balszuweit, Kirsten Lex, Rita Martello, Waltraud Burckhardt-Boer, Romano Strobelt, Markus Siegert, Horst Thiermanb, Dirk Steinritz, Annette Schmidt, Alexander Bürkle

Toxicology Letters (Elsevier) Germany, 14 September 2015

Toxicology

Key words:Poly(ADP-ribose), PARP inhibitors, sulfur mustard, nitrogen mustard, genotoxicity, HaCaT, mass spectrometry, micronucleus

Organism: Human

Cell Line: HaCaTs (human keratinocyte cell line )

619
Efficient therapy of ischaemic lesions with VEGF121-fibrin in an animal model of systemic sclerosis.

Allipour Birgani S, Mailänder M, Wasle I, Dietrich H, Gruber J, Distler O, Sgonc R

Annals of the Rheumatic Diseases (BMJ Journals) Austria, Switzerland, 11 September 2015

Rheumatology

Key words:Outcomes research, systemic sclerosis, treatment

Organism: Chicken

Tissue: Skin

Pathological State: Systemic Sclerosis

620
The ß-catenin signaling pathway induces aggressive potential in breast cancer by up-regulating the chemokine CCL5

Rika Yasuhara, Tarou Irié, Kenya Suzuki, Terumasa Sawada, Noriko Miwa, Akiko Sasaki, Yuko Tsunoda, Seigo Nakamura, Kenji Mishima

Experimental Cell Research (Elsevier) Japan, 10 September 2015

Oncology

Key words:ß-Catenin, metastasis, breast cancer, cytokines, CCL5

Organism: Human

Tissue: Breast

Pathological State: Cancer

621
Sur8/Shoc2 promotes cell motility and metastasis through activation of Ras-PI3K signaling

S Kaduwal, WJ Jeong, JC Park, KH Lee, YM Lee, SH Jeon, YB Lim, DS Min, KY Choi

Oncotarget (Impact Journals) South Korea, 05 September 2015

Oncology

Key words:Sur8, Ras, PI3K, cell migration, metastasis

Organism: Human

Tissue: Skin

Pathological State: Cancer

622
The IκB kinase inhibitor ACHP strongly attenuates TGF β1‐induced myofibroblast formation and collagen synthesis

Masum M. Mia, Ruud A. Bank

Journal of Cellular and Molecular Medicine (Wiley) The Netherlands, 04 September 2015

Cell Biology

Key words:Fibrosis, collagen, myofibroblasts, fibronectin, lysyl hydroxylase

Organism: Human

Cell Line: HDFa and HLFa Fibroblasts

623
Molecular profiling of long-term survivors identifies a subgroup of glioblastoma characterized by chromosome 19/20 co-gain

Christoph Geisenberger, Andreas Mock, Rolf Warta,Carmen Rapp, Christian Schwager, Andrey Korshunov, Ann-Katrin Nied, David Capper, Benedikt Brors, Christine Jungk, David Jones, V. Peter Collins, Koichi Ichimura, L. Magnus Bäcklund, Elena Schnabel, Michel Mittelbron, Bernd Lahrmann, Siyuan Zheng, Roel G. W. Verhaak, Niels Grabe, Stefan M. Pfister, Christian Hartmann, Andreas von Deimling, Jürgen Debus, Andreas Unterberg, Amir Abdollahi, Christel Herold-Mende

Acta Neuropathologica (Springer) Germany, UK, Japan, Sweden, USA, 01 September 2015

Pathology

Key words:Glioblastoma, molecular profiling, microglia, long-term survival, short-term survival

Organism: Human

Tissue: Brain

Pathological State: Cancer

624
Increased complexity in carcinomas: analyzing and modeling the interaction of human cancer cells with their microenvironment

Mira Stadler, Stefanie Walter, Angelika Walzl, Nina Kramer, Christine Unger, Martin Scherze, Daniela Unterleuthner, Markus Hengstschläger, Georg Krupitza, Helmut Dolznig

Seminars in Cancer Biology (Elsevier) Austria, 28 August 2015

Oncology

Key words:Carcinoma, human cancer cells, microenvironment

625
SPIO-labeled yttrium microspheres for MR imaging quantification of transcatheter intrahepatic delivery in a rodent model

W Li, Z Zhang, AC Gordon, J Chen, J Nicolai…

Radiology (Radiological Society of North America) USA, 27 August 2015

Medical Imaging

Organism: Rat

Tissue: Liver

626
Vascular Proteomics Reveal Novel Proteins Involved in SMC Phenotypic Change: OLR1 as a SMC Receptor Regulating Proliferation and Inflammatory Response

Dong Hoon Kang, Mina Choi, Soyoung Chang, Min Young Lee, Doo Jae Lee, Kyungsun Choi, Junseong Park, Eun Chun Han, Daehee Hwang, Kihwan Kwon, Hanjoong Jo, Chulhee Choi, Sang Won Kang

PLOS ONE (PLOS) South Korea, 25 August 2015

Cell Biology

Key words:Carotid arteries, small interfering RNAs, transfection, proteomics, membrane proteins, immunohistochemistry techniques, protein interaction networks, network analysis

Organism: Human

Tissue: Blood Vessels

627
Acceleration of atherogenesis in ApoE−/− mice exposed to acute or low-dose-rate ionizing radiation

Mariateresa Mancuso, Emanuela Pasquali, Ignacia Braga-Tanaka, Satoshi Tanaka, Alessandro Pannicelli, Paola Giardullo, Simonetta Pazzaglia, Soile Tapio, Michael J. Atkinson, Anna Saran

Oncotarget (Impact Journals) Italy, Japan, Germany, 22 August 2015

Oncology

Key words:Atherosclerosis, ApoE mice, radiation, aorta

Organism: Mouse

Tissue: Heart, Blood Vessels

628
Stefin B deficiency reduces tumor growth via sensitization of tumor cells to oxidative stress in a breast cancer model

M Butinar, M T Prebanda, J Rajkovic, B Jeric, V Stoka, C Peters, T Reinheckel, A Krüger, V Turk, B Turk and O Vasiljeva

Oncogene (Nature) Slovenia, Germany, USA, 19 August 2015

Oncology

Key words:Tumor cells, oxidative stress, breast cancer

Organism: Mouse

Tissue: Breast

Pathological State: Cancer

629
Differential Utilization of Dietary Fatty Acids in Benign and Malignant Cells of the Prostate

Andrea Dueregger, Bernd Schöpf, Theresa Eder, Julia Höfer, Erich Gnaiger, Astrid Aufinger, Lukas Kenner, Bernhard Perktold, Reinhold Ramoner, Helmut Klocker, Iris E. Eder

PLOS ONE (PLOS) Austria, 18 August 2015

Oncology

Key words:Prostate gland, mitochondria, glucose, glucose metabolism, mitochondrial DNA, fatty acids, cell metabolism, prostate cancer

Organism: Human

Pathological State: Cancer

Cell Line: Prostate Cancer cells

630
Impact of CYP24A1 overexpression on growth of colorectal tumour xenografts in mice fed with vitamin D and soy

Julia Höbaus, Samawansha Tennakoon, Petra Heffeter, Charlotte Groesche, Abhishek Aggarwal, Doris M. Hummel, Ursula Thiem, Rodrig Marculescu, Walter Berger, Enikö Kállay

International Journal of Cancer (Wiley) Austria, 17 August 2015

Oncology

Key words:Colon cancer, vitamin D, CYP24A1, soy, xenograft

Organism: Human

Pathological State: Cancer

Cell Line: HT29 cells (colon cancer cell line)

631
Interleukin 2 Topical Cream for Treatment of Diabetic Foot Ulcer: Experiment Protocol

SWS Chan

JMIR Research Protocols (JMIR Publications) USA, 14 August 2015

Dermatology

Key words:type 1 diabetes, topical cream, chronic wound healing, immunotherapy, IL-2

Organism: Mouse

Tissue: Skin

632
An Echinococcus multilocularis antigen B3 proteoform that shows specific antibody responses against active stage alveolar echinococcosis

CS Ahn, H Cai, JG Kim, X Han, X Ma, YA Bae, HJ Yang, I Kang, H Wang, Y Kong

Journal of Clinical Microbiology (American Society for Microbiology) China, South Korea, 12 August 2015

Microbiology

Key words:Echinococcus multilocularis, Antigen B3, Antibody Response, Alveolar Echinococcosis

Organism: Human, Mouse

Tissue: Blood

Pathological State: Bacterial Infection

633
Mesenchymal stem cell-based HSP70 promoter-driven VEGFA induction by resveratrol alleviates elastase-induced emphysema in a mouse model

Young-Bin Chen, Ying-Wei Lan, Lih-Geeng Chen, Tsung-Teng Huang, Kong-Bung Choo, Winston T. K. Cheng, Hsuan-Shu Lee , Kowit-Yu Chong

Cell Stress and Chaperones (Springer) China, 05 August 2015

Cell Biology

Key words:Stem cell-based gene therapy, resveratrol Hsp70 promoter VEGFA, mouse model, emphysema

Organism: Mouse

Tissue: Lung

634
Abstract 1091: A new image processing approach for functional context-based analysis of tryptase positive mast cells in cutaneous T-cell lymphomas

Radu Rogojanu, Johanna Eder, Waltraud Jerey, Gabriele Klosner, Verene Paulitschke, Isabella Ellinger, Theresia Thalhammer, Dan Kolmer, Franz Trautinger

Cancer Research (AACR Publications) Austria, 01 August 2015

Oncology

Key words:Image processing, tryptase positive mast cells, cutaneous, T-cell lymphoma

Organism: Human

Tissue: Skin

Pathological State: Cancer

635
Abstract 1292: Validation study on quantitative analysis method of interrelationships between immune cells and prostate epithelial and cancer cells

Gero Kramer, Lukas Kenner, Thomas Szekeres, Shahrokh Shariat, Sarah Schwarz

Cancer Research (AACR Publications) Austria, 01 August 2015

Oncology

Key words:Quantitative analysis, immune cells, prostate epithelial, cancer cells

Organism: Human

Tissue: Prostate

Pathological State: Cancer

636
Significant Therapeutic Efficacy with Combined Radioimmunotherapy and Cetuximab in Preclinical Models of Colorectal Cancer

Vessela Vassileva, Vineeth Rajkumar, Mario Mazzantini, Mathew Robson, Adam Badar, Surinder Sharma, Erik Årstad, Daniel Hochhauser, Mark F. Lythgoe, Geoffrey M. Boxer, Rosmund Barbara Pedley

The Journal of Nuclear Medicine (SNMMI) UK, 01 August 2015

Oncology

Key words:Radioimmunotherapy, cetuximab, colorectal cancer

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

637
Exchange Protein Directly Activated by cAMP (EPAC) Regulates Neuronal Polarization through Rap1B

Pablo Muñoz-Llancao, Daniel R. Henríquez, Carlos Wilson, Felipe Bodaleo, Erik W. Boddeke, Frank Lezoualc'h, Martina Schmidt, Christian González-Billault

The Journal of Neuroscience (Society for Neuroscience) The Netherlands, Chile, France, 01 August 2015

Neuroscience

Key words:Exchange protein, cAMP, neuronal polarization, Rap1B

Organism: Rat

Cell Line: Hippocampal neurons 

638
Early inflammatory responses following cell grafting in the CNS trigger activation of the subventricular zone: a proposed model of sequential cellular events

Praet J, Santermans E, Daans J, Le Blon D, Hoornaert C, Goossens H, Hens N, Van der Linden A, Berneman Z, Ponsaerts P.

Cell Transplantation (SAGE Journals) Belgium, 01 August 2015

Neuroscience

Key words:Cell transplantation, Graft apoptosis, Immune response, Angiogenesis, Cell proliferation

Organism: Mouse

Tissue: Brain

639
Outcome in Heart Failure with Preserved Ejection Fraction: The Role of Myocardial Structure and Right Ventricular Performance

Georg Goliasch, Caroline Zotter-Tufaro, Stefan Aschauer, Franz Duca, Benedikt Koell, Andreas A. Kammerlander, Robin Ristl, Irene M. Lang, Gerald Maurer, Julia Mascherbauer, Diana Bonderman

PLOS ONE (PLOS) Austria, 30 July 2015

Cardiology

Key words:Extracellular matrix, biopsy, blood pressure, heart failure, hemodynamics, echocardiography, pulmonary arteries, ejection fraction

Organism: Human

Tissue: Heart

Pathological State: Heart Failure

640
Elevated S100A9 expression in tumor stroma functions as an early recurrence marker for early-stage oral cancer patients through increased tumor cell …

WY Fang, YW Chen, JR Hsiao, CS Liu, YZ Kuo, YC Wang, KC Chang, ST Tsai, MZ Chang, SH Lin, LW Wu

Oncotarget (Impact Journals) Taiwan, 22 July 2015

Oncology

Key words:S100A9, oral cancer, recurrence, IL-6, macrophages

Organism: Human

Tissue: Skin

Pathological State: Cancer

641
Development of Blood and Lymphatic Endothelial Cells in Embryonic and Fetal Human Skin

Schuster C, Mildner M, Botta A, Nemec L, Rogojanu R, Beer L, Fiala C, Eppel W, Bauer W, Petzelbauer P, Elbe-Bürger A

American Journal of Pathology (Elsevier) Austria, 16 July 2015

Pathology

Key words:Blood, lymphatic endothelial cells, embryonic, fetal human skin

Organism: Human

Tissue: Skin

642
POLE Proofreading Mutations Elicit an Antitumor Immune Response in Endometrial Cancer

Inge C. van Gool, Florine A. Eggink, Luke Freeman-Mills, Ellen Stelloo, Emanuele Marchi, Marco de Bruyn, Claire Palles, Remi A. Nout, Cor D. de Kroon, Elisabeth M. Osse, Paul Klenerman, Carien L. Creutzberg, Ian P.M. Tomlinson, Vincent T.H.B.M. Smit, Hans W. Nijman, Tjalling Bosse, David N. Church

Clinical Cancer Research (AACR Publications) The Netherlands, UK, 15 July 2015

Oncology

Key words:Pole proofreading mutation, antitumor, immune response, endometrial cancer

Organism: Human

Tissue: Endometrium

Pathological State: Cancer

643
Langerhans Cells Maintain Local Tissue Tolerance in a Model of Systemic Autoimmune Disease

Jennifer K. King, Rachael L. Philips, Anna U. Eriksson, Peter J. Kim, Ramesh C. Halder, Delphine J. Lee, Ram Raj Singh

The Journal of Immunology (American Association of Immunologists) USA, 15 July 2015

Immunology

Key words:Lupus, langerhans cells

Organism: Mouse

Tissue: Skin

644
miR-135b- and miR-146b-dependent silencing of calcium-sensing receptor expression in colorectal tumors

Irfete S. Fetahu, Samawansha Tennakoon, Kate E. Lines, Charlotte Gröschel, Abhishek Aggarwal, Ildiko Mesteri, Sabina Baumgartner-Parzer, Robert M. Mader, Rajesh V. Thakker, Eniko Kállay

International Journal of Cancer (Wiley) Austria, UK, 14 July 2015

Oncology

Key words:Calcium-sensing receptor, microRNAs, colorectal cancer, miR-135b, miR-146b

Organism: Human

Pathological State: Cancer

Cell Line: Caco2 cells

645
mi R‐135b‐and mi R‐146b‐dependent silencing of calcium‐sensing receptor expression in colorectal tumors

Irfete S. Fetahu, Samawansha Tennakoon, Kate E. Lines, Charlotte Gröschel, Abhishek Aggarwal, Ildiko Mesteri, Sabina Baumgartner‐Parzer, Robert M. Mader, Rajesh V. Thakker , Enikő Kállay

International Journal of Cancer (Wiley) Austria, UK, 14 July 2015

Oncology

Key words:calcium‐sensing receptor, microRNAs, colorectal cancer, miR‐135b, miR‐146b

Organism: Human

Pathological State: Cancer

Cell Line: Caco2 cells, HT29 cells

646
Tumor dosimetry for I-131 trastuzumab therapy in a Her2+ NCI N87 xenograft mouse model using the Siemens SYMBIA E gamma camera with a pinhole collimator

Young Sub Lee, Jin Su Kim, Kyung Deuk Cho, Joo Hyun Kang, Sang Moo Lim

Journal of Instrumentation (IOP Science) South Korea, 06 July 2015

Oncology

Key words:Tumor dosimetry, xenograft mouse model, gamma camera, Siemens

Organism: Mouse

Pathological State: Cancer

Cell Line: Her2 Cells

647
Male-Specific Alleviation of Iron-Induced Striatal Injury by Inhibition of Autophagy

Li-Fang Wang, Kazunari K. Yokoyama, Tzu-Yin Chen, Hsiu-Wen Hsiao, Pei-Chi Chiang, Ya-Ching Hsieh, Steven Lo, Chin Hsu

PLOS ONE (PLOS) Taiwan, USA, 06 July 2015

Neuroscience

Key words:Autophagic cell death, neurons, neostriatum, neuronal tuning, histology, DNA fragmentation, mice, ovariectomy

Organism: Mouse

Tissue: Brain

Pathological State: Stratial Injury

648
T-cell Expression of IL10 Is Essential for Tumor Immune Surveillance in the Small Intestine

Kristen L. Dennis, Abdulrahman Saadalla, Nichole R. Blatner, Shuya Wang, Vysak Venkateswaran, Fotini Gounari, Hilde Cheroutre, Casey T. Weaver, Axel Roers, Nejat K. Egilmez, Khashayarsha Khazaie

Cancer Immunology Research (AACR Publications) USA, Germany, 01 July 2015

Oncology

Key words:T -cell, IL10, tumor immune surveillance, small intestine

Organism: Mouse

Tissue: Small Intestine

649
Membrane-bound Klotho is not expressed endogenously in healthy or uraemic human vascular tissue

Rik Mencke, Geert Harms, Katarina Mirkovic, Joyce Struik, Joris Van Ark, Ellen Van Loon, Melissa Verkaik, Martin H. De Borst, Clark J. Zeebregts, Joost G. Hoenderop, Marc G. Vervloet, Jan-Luuk Hillebrands

Cardiovascular Research (Oxford University Press) The Netherlands, 01 July 2015

Cardiology

Key words:Membrane-bound Klotho, uraemic human vascular tissue

Organism: Human

Tissue: Kidney, Blood Vessels

650
Noncanonical Effects of IRF9 in Intestinal Inflammation: More than Type I and Type III Interferons

Isabella Rauch, Felix Rosebrock, Eva Hainzl, Susanne Heider, Andrea Majoros, Sebastian Wienerroither, Birgit Strobl, Silvia Stockinger, Lukas Kenner, Mathias Müller, Thomas Decker

Mollecular and Cellular Biology (ASM) Austria, 01 July 2015

Immunology

Key words:IRF9, intestinal inflammation, interferons

Organism: Mouse

Tissue: Colon

Pathological State: Colitis

651
miR-22 and miR-29a are members of the androgen receptor cistrome modulating LAMC1 and Mcl-1 in prostate cancer

Lorenza Pasqualini, Huajie Bu, Martin Puhr, Narisu Narisu, Johannes Rainer, Bettina Schlick, Georg Schäfer, Mihaela Angelova, Zlatko Trajanoski, Stefan T. Börno, Michal R. Schweiger, Christian Fuchsberger, Helmut Klocker

Molecular Endocrinology (Oxford University Press) Austria, USA, Italy, Germany, 01 July 2015

Endocrinology, Oncology

Key words:miR-22 , miR-29a ,Androgen Receptor Cistrome, LAMC1, Mcl-1, Prostate Cancer

Organism: Human

Tissue: Prostate

Pathological State: Cancer

652
Precision-cut kidney slices (PCKS) to study development of renal fibrosis and efficacy of drug targeting ex vivo

Fariba Poosti, Bao Tung Pham, Dorenda Oosterhuis, Klaas Poelstra, Harry van Goor, Peter Olinga, Jan-Luuk Hillebrands

Disease Models and Mechanisms (The Company of Biologists) The Netherlands, 24 June 2015

Nephrology

Key words:Drug targeting, Fibrosis, Kidney, Tissue slices

Organism: Mouse

Tissue: Kidney

Pathological State: Fibrosis

653
Lanreotide-conjugated PEG-DSPE micelles: an efficient nanocarrier targeting to somatostatin receptor positive tumors

Nan Zheng, Wenbing Dai, Hua Zhang, Xueqing Wang, Jiancheng Wang, Xuan Zhang, Kun Wang, Jian Lia, Qiang Zhang

Journal of Drug Targeting (Taylor and Francis) China, 24 June 2015

Oncology

Key words:Lanreotide, over-express somatostatin receptor 2, 2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy (poly-(ethylene glycol))-2000]

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

654
Memantine attenuates delayed vasospasm after experimental subarachnoid hemorrhage via modulating endothelial nitric oxide synthase

CY Huang, LC Wang, YS Shan, CH Pan, KJ Tsai

International Journal of Molecular Sciences (MDPI) Taiwan, 23 June 2015

Neuroscience

Key words:memantine; nitric oxide synthase; subarachnoid hemorrhage; vasospasm

Organism: Rat

Tissue: Brain

Pathological State: Vasospasm

655
STAT3 regulated ARF expression suppresses prostate cancer metastasis

Jan Pencik, Michaela Schlederer, Wolfgang Gruber, Christine Unger, Steven M. Walker, Athena Chalaris, Isabelle J. Marié, Melanie R. Hassler, Tahereh Javaheri, Osman Aksoy, Jaine K. Blayney, Nicole Prutsch, Anna Skucha, Merima Herac, Oliver H. Krämer, Peter Mazal, Florian Grebien, Gerda Egger, Valeria Poli, Wolfgang Mikulits et al.

Nature Communications (Nature) Austria, UK, Germany, USA, Italy, Sweden, 22 June 2015

Oncology

Key words:STAT3 and p14ARF expression, PI3K–AKT–mTOR signalling pathway, ARF–Mdm2–p53 tumour suppressor axis

Organism: Mouse

Tissue: Xenograft Tumor, Colon

Pathological State: Cancer

656
The Role of ExoS in Dissemination of Pseudomonas aeruginosa during Pneumonia

Stephanie M. Rangel, Maureen H. Diaz, Claire A. Knoten, Angelica Zhang, Alan R. Hauser

Plos Pathogens (PLOS) USA, 19 June 2015

Pulmonology

Key words:Pneumocytes, pneumonia, bacterial pathogens, pseudomonas aeruginosa, pulmonary imaging, cell staining, phagocytes, blood

Organism: Mouse

Tissue: Lung

Pathological State: Pneumonia

657
Endothelial-to-mesenchymal transition contributes to fibro-proliferative vascular disease and is modulated by fluid shear stress

Jan-Renier A.J. Moonen, Ee Soo Lee, Marc Schmidt, Monika Maleszewska, Jasper A. Koerts, Linda A. Brouwer, Theo G. Van Kooten, Marja J.A. Van Luyn, Clark J. Zeebregts, Guido Krenning, Martin C. Harmsen

Cardiovascular Research (Oxford University Press) The Netherlands, Germany, 17 June 2015

Cardiology

Key words:LRRFIP1, EMT, Wnt/β-catenin signaling, β-catenin destruction complex, Reverse EMT

Organism: Human

Cell Line: HUVECs (Human umbilical vein endothelial cells)

658
Left Shift 1+ flag for the detection of band neutrophils: interlaboratory variations and recommendations for the routine laboratory

F. WEERKAMP, P. H. TAAL, B. A. De BOER and ON BEHALF OF THE ADdifVIA WORKING GROUP

International Journal of Laboratory Hematology (Wiley) The Netherlands, 16 June 2015

Hematology

Key words:Differential leukocyte count, left shift flag, band neutrophils, routine laboratory

Organism: Human

Cell Line: Blood

659
Image analysis for accurately counting CD4+ and CD8+ T cells in human tissue

Kurt Diema, Amalia Magaret, Alexis Klock, Lei Jina, Jia Zhu, Lawrence Corey

Journal of Virological Methods (Elsevier) USA, 12 June 2015

Virology

Key words:Cell counting, immunohistochemistry (IHC), software cell counting, HSV-2, cellProfiler

Organism: Human

Tissue: Penis

Pathological State: Virus Infection

660
Sorafenib and its derivative SC-1 exhibit antifibrotic effects through signal transducer and activator of transcription 3 inhibition

Tung-Hung Su, Chung-Wai Shiau, Ping Jao, Chen-Hua Liu, Chun-Jen Liu, Wei-Tien Tai, Yung-Ming Jeng, Hung-Chih Yang, Tai-Chung Tseng, Hsiang-Po Huang, Huei-Ru Cheng, Pei-Jer Chen, Kuen-Feng Chen, Jia-Horng Kao, Ding-Shinn Chen

PNAS (PNAS) Taiwan, 09 June 2015

Cell Biology

Key words:Hepatic stellate, cell STAT3 SHP-1, hepatitis B, liver fibrosis

661
298 MAST CELLS ARE ABUNDANT IN CUTANEOUS T‐CELL LYMPHOMAS AND CORRELATE WITH DISEASE STAGE

P. Gorniak, B. Budziszewska, B. Pula, M. Wasylecka, K. Borg, G. Nowak, H. Makuch - Lasica, E. Lech - Maranda, K. Warzocha, P. Juszczynski

Hematological Oncology (Wiley) Poland, 09 June 2015

Oncology

Key words:Cerebral ischemia–reperfusion injury, oxidative stress, apoptosis, superoxide, NADPH oxidase

Organism: Human

Tissue: Lymphoid Tissue

662
The Dishevelled-binding protein CXXC5 negatively regulates cutaneous wound healing

Soung-Hoon Lee, Mi-Yeon Kim, Hyun-Yi Kim, Young-Mi Lee, Heesu Kim, Kyoung Ae Nam, Mi Ryung Roh, Do Sik Min, Kee Yang Chung, Kang-Yell Choi

The Journal of Experimental Medicine (Rockefeller University Press) South Korea, 08 June 2015

Regenerative Medicine

Key words:Idiopathic pulmonary fibrosis, mesenchymal stem cell, mitochondrial membrane

Organism: Human

Tissue: Skin

Pathological State: Skin Wound

663
ERG Activates the YAP1 Transcriptional Program and Induces the Development of Age-Related Prostate Tumors

Liem T. Nguyen, Maria S. Tretiakova, Mark R. Silvis, Jared Lucas, Olga Klezovitch, Ilsa Coleman, Hamid Bolouri, Vassily I. Kutyavin, Colm Morrissey, Lawrence D. True, Peter S. Nelson, Valeri Vasioukhin

Cancer Cell (Cell Press) USA, 08 June 2015

Oncology

Key words:Prostate cancer, actin cytoskeleton

Organism: Human

Tissue: Prostate

Pathological State: Cancer

664
CD47 blockade inhibits tumor progression human osteosarcoma in xenograft models

JF Xu, XH Pan, SJ Zhang, C Zhao, BS Qiu, HF Gu, JF Hong, L Cao, Y Chen, B Xia, Q Bi, YP Wang

Oncotarget (Impact Journals) China, 08 June 2015

Oncology

Key words:osteosarcoma, CD47, antibody, immunotherapy

Organism: Mouse

Tissue: Lung, Xenograft Tumor

Pathological State: Cancer

665
AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis

Jino Park, Michaela Schlederer, Martin Schreiber, Ryan Ice, Olaf Merkel, Martin Bilban, Sebastian Hofbauer, Soojin Kim, Joseph Addison, Jie Zou, Chunyan Ji, Silvia T. Bunting, Zhengqi Wang, Menachem Shoham, Gang Huang, Zsuzsanna Bago-Horvath, Laura F. Gibson, Yon Rojanasakul, Scot Remick, Alexey Ivanov, Elena Pugacheva, Kevin D. Bunting, Richard Moriggl, Lukas Kenner, William Tse

Oncotarget (Impact Journals) USA, Austria, Germany, China, 07 June 2015

Oncology

Key words:AF1q, TCF7, CD44, Wnt, metastasis

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

666
Atopic donor status does not influence the uptake of the major grass pollen allergen, Phl p 5, by dendritic cells

Kazem Ashjaei, Dieter Palmberger, Merima Bublin, Erika Bajna, Heimo Breiteneder, Reingard Grabherr, Isabella Ellinger, Karin Hoffmann-Sommergruber

Journal of Immunological Methods (Elsevier) Austria, 05 June 2015

Immunology

Key words:Allergen; Endocytosis; Grass pollen; Monocyte derived dendritic cells; Phl p 5; SF-nsLTP

Organism: Human

Pathological State: Allergy

Cell Line: Blood

667
Mast cell-macrophage dynamics in modulation of dengue virus infection in skin

Ya-Ting Chu, Shu-Wen Wan, Robert Anderson, Yee-Shin Lin

Immunology (Wiley) Taiwan, Canada, 04 June 2015

Immunology

Key words:Dengue virus, KitW-sh/W-sh mice, macrophage, mast cell

Organism: Mouse

Tissue: Skin

Pathological State: Virus Infection

668
Synergistic antitumor effects of radiation and proteasome inhibitor treatment in pancreatic cancer through the induction of autophagy and the downregulation of TRAF6

Hui-Wen Chiu, Shu-Wen Lin, Li-Ching Lin, Yung-Ho Hsu, Yuh-Feng Lin, Sheng-Yow Ho, Yuan-Hua Wu, Ying-Jan Wang

Cancer Letters (Elsevier) Taiwan, 04 June 2015

Oncology

Key words:Radiation; Proteasome inhibitor; Autophagy; Endoplasmic reticulum stress; Pancreatic cancer

Organism: Mouse

Tissue: Xenograft Tumor, Pancreas

Pathological State: Cancer

669
Silencing of LRRFIP1 reverses the epithelial–mesenchymal transition via inhibition of the Wnt/β-catenin signaling pathway

Daisuke Douchi, Hideo Ohtsuka, Kyohei Ariake, Kunihiro Masuda, Shuhei Kawasaki, Kei Kawaguchi, Koji Fukase, Masaya Oikawa, Fuyuhiko Motoi, Takeshi Naitoh, Yu Katayose, Shinichi Egawa, Michiaki Unno

Cancer Letters (Elsevier) Japan, 03 June 2015

Oncology

Key words:LRRFIP1; EMT; Wnt/β-catenin signaling; β-catenin destruction complex; Reverse EMT

Organism: Human

Tissue: Pancreas

Pathological State: Cancer

670
Clinically applicable magnetic-labeling of natural killer cells for MRI of transcatheter delivery to liver tumors: preclinical validation for clinical translation

Kangan Li, Andrew C Gordon, Linfeng Zheng, Weiguo Li, Yang Guo, Jing Sun, Guixiang Zhang, Guohong Han, Andrew C Larson, Zhuoli Zhang

Nanomedicine (Future Medicine) China, USA, 01 June 2015

Nanomedicine

Key words:Intraportal vein, heparin-protamine-ferumoxytol, HPF-labeled NK cells

Organism: Rat

Tissue: Xenograft Tumor, Liver

Pathological State: Cancer

671
Prognostic Significance and Determinants of the 6-Min Walk Test in Patients With Heart Failure and Preserved Ejection Fraction

Caroline Zotter-Tufaro, Julia Mascherbaue, Franz Duca, Benedikt Koell, Stefan Aschaue, Andreas A. Kammerlande, Adelheid Panzenboeck, Roela Sadushi-Kolici, Christine Bangert, Daniela Laimer, Robin Ristl, Irene M. Lang, Diana Bonderman

JACC: Heart Failure (Elsevier) Austria, 01 June 2015

Cardiology

Key words:cardiac catheterization; exercise test; extracellular matrix; pulmonary circulation

Organism: Human

Tissue: Heart

Pathological State: Fibrosis

672
Mastocytosis: the new differential diagnosis of CD30-positive neoplasms

Irina Maric, Katherine R. Calvoa

Leukemia and Lymphoma (Taylor and Francis) USA, 01 June 2015

Oncology

Key words:Mastocytosis disease

673
Paracrine factors of human amniotic fluid-derived mesenchymal stem cells show strong anti-fibrotic properties by inhibiting myofibroblast differentiation and …

MM Mia, RA Bank

Journal of Stem Cell Research and Therapy (OMICS) The Netherlands, 21 May 2015

Stem Cell Research

Key words:Fibrosis; Fibroblasts; Myofibroblasts; TGFβ1; Mesenchymal stem cells; Extracellular matrix

Organism: Human

Cell Line: Adipose tissue derived stromal cells (ADSC)

674
Hypoxia-preconditioned mesenchymal stem cells attenuate bleomycin-induced pulmonary fibrosis

Ying-Wei Lan, Kong-Bung Choo, Chuan-Mu Chen, Tsai-Hsien Hung, Young-Bin Chen, Chung-Hsing Hsieh, Han-Pin Kuo, Kowit-Yu Chong

Stem Cell Research and Therapy (Springer) China, Malaysia, 20 May 2015

Stem Cell Research

Key words:Bleomycin, diopathic pulmonary fibrosis, hypoxia-inducible factor, hepatocyte growth factor, connective tissue growth factor

Organism: Mouse

Tissue: Lung

Pathological State: Fibrosis

675
Suppression of NADPH oxidase- and mitochondrion-derived superoxide by Notoginsenoside R1 protects against cerebral ischemia–reperfusion injury through estrogen receptor-dependent activation of Akt/Nrf2 pathways

X. Meng, M. Wang, X. Wang, G. Sun, J. Ye, H. Xu, X. Sun

Free Radical Research (Taylor and Francis) China, 20 May 2015

Neuroscience

Key words:Cerebral ischemia–reperfusion injury, oxidative stress, apoptosis, superoxide, NADPH oxidase

Organism: Rat

Tissue: Brain

Pathological State: Cerebral Ischemia

676
Texture analysis of 125I-A5B7 anti-CEA antibody SPECT differentiates metastatic colorectal cancer model phenotypes and anti-vascular therapy response

V Rajkumar, V Goh, M Siddique, M Robson, G Boxer, RB Pedley, GJR Cook

British Journal of Cancer (Wiley) UK, 19 May 2015

Oncology

Key words:Cancer models, Colorectal cancer Computed tomography Tumour heterogeneity

Organism: Mouse

Tissue: Liver

Pathological State: Cancer

677
Intracellular calcium levels as screening tool for nanoparticle toxicity

Claudia Meindl, Tatjana Kueznik, Martina Bösch, Eva Roblegg, Eleonore Fröhlich

Journal of Applied Toxicology (Wiley) Austria, 14 May 2015

Toxicology

Key words:Nanoparticles, cytotoxicity, apoptosis, lysosomes, calcium imaging

Organism: Human

Cell Line: EAhy926 cells (Human endothelial cell line)

678
Expression of Interferon γ by Decidual Cells and Natural Killer Cells at the Human Implantation Site

Chie-Pein Chen,Longzhu Piao, Xilin Chen, Jianhua Yu, Rachel Masch, Frederick Schatz, Charles J. Lockwood, S. Joseph Huang

Reproductive Sciences (SAGE Journals) Taiwan, USA, 11 May 2015

Reproductive Medicine

Key words:Interferon γ, NK cells, decidual cells

Organism: Human

Tissue: Endometrium

679
The systemic multiplication of Gallibacterium anatis in experimentally infected chickens is promoted by immunosuppressive drugs which have a less specific effect on the depletion of leukocytes

Surya Paudel, Claudia Hess, Patricia Wernsdorf, Tobias Käser, Sarah Meitz, Erika Jensen-Jarolim, Michael Hess, Dieter Liebhart

Veterinary Immunology and Immunopathology (Elsevier) Austria, 08 May 2015

Immunology

Key words:Gallibacterium anatis, chickensc, leukocyte quantification, non-selective immunosuppression

Organism: Chicken

Tissue: Spleen

Pathological State: Bacterial Infection

680
K-Ras stabilization by estrogen via PKCδ is involved in endometrial tumorigenesis

KH Koo, WJ Jeong, YH Cho, JC Park, DS Min, KY Choi

Oncotarget (Impact Journals) South Korea, 08 May 2015

Oncology

Key words:endometrial cancer, estrogen, tumorigenesis, K-Ras, PKCδ

Organism: Human

Tissue: Endometrium

Pathological State: Cancer

681
siRNA-based spherical nucleic acids reverse impaired wound healing in diabetic mice by ganglioside GM3 synthase knockdown

Pratik S. Randeria, Mark A. Seeger, Xiao-Qi Wang, Heather Wilson, Desmond Shipp, Chad A. Mirkin, Amy S. Paller

PNAS (PNAS) USA, 05 May 2015

Dermatology

Key words:SNA, nanoparticle, siRNA, GM3 synthase, diabetic wound healing

Organism: Mouse

Tissue: Adipose Tissue, Muscle

Pathological State: Obesity, Diabetes

682
CCL7 contributes to the TNF-alpha-dependent inflammation of lesional psoriatic skin

Patrick M. Brunner, Elisabeth Glitzner, Baerbel Reininger, Irene Klein, Georg Stary, Michael Mildner, Pavel Uhrin, Maria Sibilia, Georg Stingl

Experimental Dermatology (Wiley) Austria, 04 May 2015

Dermatology

Key words:CCL7, chemokines, myeloid cells, psoriasis, TNF-α

Organism: Human

Tissue: Skin

Pathological State: Psoriasis

683
Effect of Sodium-Glucose Cotransport Inhibition on Polycystic Kidney Disease Progression in PCK Rats

Sarika Kapoor, Daniel Rodriguez, Meliana Riwanto, Ilka Edenhofer, Stephan Segerer, Katharyn Mitchell, Rudolf P. Wüthrich

PLOS ONE (PLOS) Switzerland, 30 April 2015

Nephrology

Key words:sodium-glucose-cotransporter-2 (SGLT2), polycystic kidney disease, aquaretic drug tolvaptan

Organism: Rat

Tissue: Kidney

Pathological State: Polycystic Kidney Disease

684
Frontal cortex and hippocampus neurotransmitter receptor complex level parallels spatial memory performance in the radial arm maze

Bharanidharan Shanmugasundaram, Ajinkya Sase, András G. Miklosi, Fernando J. Sialana, Saraswathi Subramaniyan, Yogesh D. Aher, Marion Gröger, Harald Höger, Keiryn L. Bennett, Gert Lubec

Behavioural Brain Research (Elsevier) Austria, 28 April 2015

Neuroscience

Key words:Radial arm maze; Neurotransmitter receptor complex; Blue native PAGE; Spatial memory; D1-GluN1 complex

Organism: Rat

Tissue: Brain

685
Oncogenic role of miR-155 in anaplastic large cell lymphoma lacking the t(2;5) translocation

Olaf Merkel, Frank Hamacher, Robert Griessl, Lisa Grabner, Ana-Iris Schiefer, Nicole Prutsch, Constance Baer, Gerda Egger, Michaela Schlederer, Peter William Krenn, Tanja Nicole Hartmann, Ingrid Simonitsch-Klupp, Christoph Plass, Philipp Bernhard Staber, Richard Moriggl, Suzanne D Turner, Richard Greil, Lukas Kenner

Journal of Pathology (Wiley) Germany, Austria, UK, 27 April 2015

Oncology

Key words:miR-155, ALCL, ALK kinase, cytokines, IL-21, IL-22, IL-10

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

686
Enhancer of zeste homolog-2 (EZH2) methyltransferase regulates transgelin/smooth muscle-22α expression in endothelial cells in response to interleukin-1β and transforming growth factor-β2

Monika Maleszewska, Rutger A.F. Gjaltema, Guido Krenning, Martin C. Harmsen

Cellular Signalling (Elsevier) The Netherlands, 24 April 2015

Cell Biology

Key words:Endothelial cell, EZH2; SM22α, inflammation, fibrosis, chromatin

Organism: Human

Cell Line: HUVECs (Human umbilical vein endothelial cells)

687
Deoxycholate bile acid directed synthesis of branched Au nanostructures for near infrared photothermal ablation

Dong-Hyun Kima, Andrew C. Larson

Biomaterials (Elsevier) USA, 17 April 2015

Nanomedicine

Key words:Gold nanoparticles, bile acid, green chemistry, photothermal treatment, nanomedicine

Organism: Mouse

Tissue: Xenograft Tumor, Pancreas

Pathological State: Cancer

688
A-kinase-anchoring proteins coordinate inflammatory responses to cigarette smoke in airway smooth muscle

Wilfred J. Poppinga, Irene H. Heijink, Laura J. Holtzer, Philipp Skroblin, Enno Klussmann, Andrew J. Halayko, Wim Timens, Harm Maarsingh, Martina Schmidt

American Journal of Physiology (APS Journals) The Netherlands, Germany, Canada, USA, 15 April 2015

Pulmonology

Key words:CX3CR1, cuprizone, demyelination, spectroscopy, MRI

Organism: Human

Tissue: Lung

Pathological State: Chronic Obstructive Pulmonary Disease

689
Cytotoxity of nanoparticles is influenced by size, proliferation and embryonic origin of the cells used for testing

Eleonore Fröhlich, Claudia Meindl, Eva Roblegg, Antonia Griesbacher, Thomas R. Pieber

Nanotoxicology (Taylor and Francis) Austria, 13 April 2015

Toxicology

Key words:Calcium-sensing receptor, tumor suppressor, colon Inflammation, cancer EMT, cancer stem cell, calcimimetic

Organism: Human

Cell Line: EAhy926 cells (Human endothelial cell line)

690
Der p2 internalization by epithelium synergistically augments toll-like receptor-mediated proinflammatory signaling

SC Yin, EC Liao, CL Chiu, CY Chang, JJ Tsai

Allergy, Asthma and Immunology Research (Kamje Press) Taiwan, 10 April 2015

Allergy

Key words:Internalization; Der p2; human airway epithelium; Toll-like receptor 2; inflammation; calcitriol

Organism: Human

Tissue: Nasal Mucosa

691
Papain Degrades Tight Junction Proteins of Human Keratinocytes In Vitro and Sensitizes C57BL/6 Mice via the Skin Independent of its Enzymatic Activity or TLR4 Activation

Caroline Stremnitzer, Krisztina Manzano-Szalai, Anna Willensdorfer, Philipp Starkl, Mario Pieper, Peter König, Michael Mildner, Erwin Tschachler, Ursula Reichart, Erika Jensen-Jarolim

Journal of Investigative Dermatology (Elsevier) Austria, Germany, 09 April 2015

Dermatology

Key words:Dermatophagoides pteronyssinus, transepidermal water loss, phosphate-buffered saline, Toll-like receptor 4

Organism: Mouse

Tissue: Skin

692
EBV Oncogene N-LMP1 Induces CD4 T Cell–Mediated Angiogenic Blockade in the Murine Tumor Model

The Journal of Immunology (American Association of Immunologists) China, 06 April 2015

Oncology

Key words:Antiangiogenic N-LMP1–specific T cell, Tumor single cells, In vivo angiogenesis assays

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

693
Molecular characterization of whole mount prostate specimens using 5-color fluorescence labeling, virtual slide technology and automated image analysis

Georg E. Steiner, Gwenaelle Gaillard, Karina Pfeil, Claudia Strele, Christine Linder, Vincent Laurain, Radu Rogojanu, Rupert C. Ecker, Katja Oesterreicher, Lukas Kenner, Johannes Schmid, Helmut Klocker

Cancer Research (AACR Publications) Austria, 01 April 2015

Medical Image Analysis

Key words:Prostate tissue samples, tubular epithelial ducts, epithelial and non-epithelial cells

694
Chondroitin sulfate-polyethylenimine copolymer-coated superparamagnetic iron oxide nanoparticles as an efficient magneto-gene carrier for microRNA-encoding …

YL Lo, HL Chou, ZX Liao, SJ Huang, JH Ke, YS Liu, CC Chiu, LF Wang

Nanoscale (Royal Society of Chemistry) Taiwan, 01 April 2015

Nanomedicine

Key words:Magnetofection, MicroRNA, Glioblastoma, Gene delivery

Organism: Human

Pathological State: Cancer

Cell Line: U87 cells

695
Lung-specific loss of α3 laminin worsens bleomycin-induced pulmonary fibrosis

LI Morales-Nebreda, MR Rogel…

American Journal of Respiratory Cell and Molecular Biology (ATS Journals) USA, Mexico, 01 April 2015

Pulmonology

Key words:laminin; matrix; pulmonary fibrosis; development

Organism: Mouse

Tissue: Lung

Pathological State: Fibrosis

696
nk4a/Arf-Dependent Loss of Parietal Cells Induced by Oxidative Stress Promotes CD44-Dependent Gastric Tumorigenesis

Ryo Seishima, Takeyuki Wada, Kenji Tsuchihashi, Shogo Okazaki, Momoko Yoshikawa, Hiroko Oshima, Masanobu Oshima, Toshiro Sato, Hirotoshi Hasegawa, Yuko Kitagawa, James R. Goldenring, Hideyuki Saya, Osamu Nagano

Cancer Prevention Research (AACR Publications) Japan, USA, 26 March 2015

Oncology

Key words:Spasmolytic polypeptide–expressing metaplasia, reactive oxygen species, parietal cells

Organism: Mouse

Tissue: Stomach

697
Trained immunity in newborn infants of HBV-infected mothers

Michelle Hong, Elena Sandalova, Diana Low, Adam J. Gehring, Stefania Fieni, Barbara Amadei, Simonetta Urbani, Yap-Seng Chong, Ernesto Guccione, Antonio Bertoletti

Nature Communications (Nature) Singapore, Italy, UK, 25 March 2015

Immunology, Virology

Key words:Calcium-sensing receptor, colon cancer, calcium, vitamin D, chemoprevention, calcimimetic

Organism: Human

Pathological State: Virus Infection

Cell Line: CD2- cells (non-T non-NK cells)

698
Low-dose irradiation affects expression of inflammatory markers in the heart of ApoE-/-mice

Daniel Mathias, Ronald E. J. Mitchel, Mirela Barclay, Heather Wyatt, Michelle Bugden, Nicholas D. Priest, Stewart C. Whitman †, Markus Scholz, Guido Hildebrandt, Manja Kamprad, Annegret Glasow

Plos One (PLOS) Germany, Canada, 23 March 2015

Cardiology

Key words:Collagens, Dosimetry, Inflammation ,Fibrinogen ,Blood plasma ,Heart ,White blood cells ,Endothelial cells

Organism: Mouse

Tissue: Heart

699
Reproductive Sciences

Reproductive Sciences (SAGE Journals) , 22 March 2015

Reproductive Medicine

700
Tissue Microarrays for Translational Research

Ronald Simon, Martina Mirlacher

Microarrays in Diagnostics and Biomarker Development (Springer) Germany, 19 March 2015

Biological Methods

Key words:Tissue microarray,

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