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Customer Publications (A total of 1249 papers published)

501
OX40 ligand newly expressed on bronchiolar progenitors mediates influenza infection and further exacerbates pneumonia

Taizou Hirano, Toshiaki Kikuchi, Naoki Tode, Arif Santoso, Mitsuhiro Yamada, Yoshiya Mitsuhashi, Riyo Komatsu, Takeshi Kawabe, Takeshi Tanimoto, Naoto Ishii, Yuetsu Tanaka, Hidekazu Nishimura, Toshihiro Nukiwa, Akira Watanabe, Masakazu Ichinose

EMBO Molecular Medicine (Wiley) Japan, 14 March 2016

Pathology

Key words:Bronchioles, glycosylation regeneration, OX40 ligand, viral pneumonia

Organism: Dog

Pathological State: Virus Infection

Cell Line: MDCK cells

502
Internalization of nanopolymeric tracers does not alter characteristics of placental cells

Paolo Bigini, Elisa R. Zanier, Silvia Saragozza, Simona Maciotta, Pietro Romele, Patrizia Bonassi Signoroni, Antonietta Silini, Francesca Pischiutta, Eliana Sammali, Claudia Balducci, Martina B. Violatto, Laura Talamini, David Garry, Davide Moscatelli, Ra

Journal of Cellular and Molecular Medicine (Wiley) Italy, 14 March 2016

Cell Biology

Key words:Cell tracing, nanoparticles, mesenchymal stem/stromal cells, placenta, amnion, chorion, hypoxia, ischaemia

Organism: Human

Tissue: Placenta

503
Acquisition of chemoresistance and other malignancy-related features of colorectal cancer cells are incremented by ribosome-inactivating stress

CK Oh, SJ Lee, SH Park, Y Moon

Journal of Biological Chemistry (ASBMB) South Korea, 09 March 2016

Oncology

Key words:Ribosome-inactivating stress (RIS); Colorectal cancer; Activating transcription factor 3 (ATF3); Macrophage inhibitory cytokine-1 (MIC-1); Chemosensitivity

Organism: Mouse

Tissue: Allograft Tumor, Colon

Pathological State: Cancer

504
In primary Sjögren's syndrome high absolute numbers and proportions of B cells in parotid glands predict responsiveness to rituximab as defined by ESSDAI, but not by SSRI

Konstantina Delli, Erlin A Haacke, Frans GM Kroese, Rodney P Pollard, Stephan Ihrler, Bert van der Vegt, Arjan Vissink, Hendrika Bootsma, Frederik KL Spijkervet

Annals of the Rheumatic Diseases (BMJ) The Netherlands, 09 March 2016

Rheumatology

Key words:Sjogren's syndrome, b cells, parotide glands, rituximab

Organism: Human

Tissue: Salivary Gland

Pathological State: Sjögren's Syndrome

505
Exploring the role of sphingolipid machinery during the epithelial to mesenchymal transition program using an integrative approach

Anastasia Meshcheryakova, Martin Svoboda, Ammar Tahir, Harald C. Köfeler, Alexander Triebl, Felicitas Mungenast, Georg Heinze, Christopher Gerner, Philip Zimmermann, Markus Jaritz, and Diana Mechtcheriakova

Oncotarget (NCBI) Austria, Switzerland, 07 March 2016

Oncology

Key words:sphingolipid-related targets, sphingosine 1-phosphate/ceramide rheostat, multigene signature, epithelial to mesenchymal transition, lung cancer

Organism: Human

Pathological State: Cancer

Cell Line: lung adenocarcinoma epithelial cell line, A549

506
Intrathecal transplantation of embryonic stem cell-derived spinal GABAergic neural precursor cells attenuates neuropathic pain in a spinal cord injury rat model

Insik Hwang, Suk-Chan Hahm Suk-Chan Hahm, Kyung-Ah Choi, Sung-Ho Park, Hyesun Jeong, Ji-Hye Yea, Junesun Kim, Ph.D., Sunghoi Hong, Ph.D.

Cell Transplantation (SAGE Journals) South Korea, 01 March 2016

Regenerative Medicine

Key words:Spinal cord injury (SCI), Neuropathic pain, Spinal GABAergic neurons, Intrathecal transplantation

Organism: Rat

Tissue: Spinal Cord

Pathological State: Spinal Cord Injury

507
Platelet-rich plasma influences expansion and paracrine function of adipose-derived stromal cells in a dose-dependent fashion

Willemsen, Joep C. N.; Spiekman, Maroesjka; Stevens, H. P. Jeroen; van der Lei, Berend; Harmsen, Martin C.

Plastic and Reconstructive Surgery (Ingentaconnect) The Netherlands, 01 March 2016

Regenerative Medicine

Organism: Human

Tissue: Adipose Tissue

508
Double Linear Gradient Biointerfaces for Determining Two-Parameter Dependent Stem Cell Behavior

Patrick Van Rijn, Philipp Kuhn, Qihui Zhou, Torben Van Der Boon, Aneta Schaap-Oziemlak, Theo Van Kooten

ChemNanoMat (Wiley) The Netherlands, 26 February 2016

Biological Methods

Key words:Biointerfaces, gradients, stem cell, wettability, stiffness

Organism: Human

Cell Line: hBM-MSC (mesenchymal stem cells from human bone marrow)

509
Fenretinide: a potential treatment for endometriosis

Mary Ellen Pavone, Saurabh S. Malpani, Matthew Dyson, J. Julie Kim, Serdar E. Bulun

Reproductive Sciences (SAGE Journals) USA, 25 February 2016

Reproductive Medicine

Key words:endometriosis, fenretinide, apoptosis, retinol, retinoid, STRA6, retinoic acid

Organism: Mouse

Tissue: Endometrium

Pathological State: Endometriosis

510
Cooperation of ETV6/RUNX1 and BCL2 enhances immunoglobulin production and accelerates glomerulonephritis in transgenic mice

Eva Bauer, Michaela Schlederer, Ruth Scheicher, Jaqueline Horvath, Petra Aigner, Ana-Iris Schiefer, Renate Kain, Heinz Regele, Gregor Hoermann, Günter Steiner, Lukas Kenner, Veronika Sexl, Andreas Villunger, Richard Moriggl, and Dagmar Stoiber

Oncotarget (NCBI) Austria, 23 February 2016

Oncology

Key words:ETV6/RUNX1, BCL2, glomerulonephritis, lymphoma, autoimmunity, Immunology and Microbiology Section, Immune response, Immunity

Organism: Mouse

Tissue: Kidney

511
In situ analysis of intrahepatic virological events in chronic hepatitis B virus infection

Xiaonan Zhang, Wei Lu, Ye Zheng, Weixia Wang, Lu Bai, Liang Chen, Yanling Feng, Zhanqing Zhang, and Zhenghong Yuan

The Journal of Clinical Investigation (American Society of Clinical Investigation) China, 22 February 2016

Virology

Key words:intrahepatic virological events, chronic hepatitis B virus infection

Organism: Human

Tissue: Liver

Pathological State: Virus Infection

512
In EXOG-depleted cardiomyocytes cell death is marked by a decreased mitochondrial reserve capacity of the electron transport chain

Wardit Tigchelaar, Anne Margreet De Jong, Wiek H. van Gilst, Rudolf A. De Boer, Herman H.W. Silljé

Inside the Cell (Wiley) The Netherlands, 18 February 2016

Cell Biology

Key words:Cardiomyocyte, cell death, EXOG, hypertrophy, mitochondria

Organism: Rat

Cell Line: NRVC cells ( neonatal rat ventricular cardiomyocytes )

513
Fc receptor-mediated phagocytosis in tissues as a potent mechanism for preventive and therapeutic HIV vaccine strategies

M Sips, M Krykbaeva, T J Diefenbach, M Ghebremichael, B A Bowman, A-S Dugast, A W Boesch, H Streeck, D S Kwon, M E Ackerman, T J Suscovich, P Brouckaert, T W Schacker & G Alter

Mucosal Immunology (Nature) USA, Belgium, Germany, 17 February 2016

Key words:Cell signalling, HIV infections, Phagocytosis, Vaccines

514
Aging has small effects on initial ischemic acute kidney injury development despite changing intrarenal immunologic micromilieu in mice

Hye Ryoun Jang, Ji Hyeon Park, Ghee Young Kwon, Jae Berm Park, Jung Eun Lee, Dae Joong Kim, Yoon-Goo Kim, Sung Joo Kim, Ha Young Oh, Wooseong Huh

American Journal of Physiology (APS) South Korea, 15 February 2016

Physiology

Key words:Aging, ischemic, kidney injury, immunologic, micromilieu

Organism: Mouse

Tissue: Kidney

Pathological State: Kidney Injury

515
The in vitro response of tissue stem cells to irradiation with different LETs

Peter W. Nagle, Nynke A. Hosper, Emily M. Ploeg, Marc-Jan van Goethem, Sytze Brandenburg, Johannes A. Langendijk, Roland K. Chiu, Robert P. Coppes

International Journal of Radiation Oncology (Elsevier) The Netherlands, 12 February 2016

Oncology

Key words:In vitro, tissue stem cells, irradiantion, LETs

Organism: Human

Cell Line: HSG cells (human salivary gland cells)

516
Far-infrared promotes burn wound healing by suppressing NLRP3 inflammasome caused by enhanced autophagy

Hui-Wen Chiu, Cheng-Hsien Chen, Jen-Ning Chang, Chien-Hsiung Chen, Yung-Ho Hsu

Journal of Molecular Medicine (Springer) Taiwan, 11 February 2016

Regenerative Medicine

Key words:Far-infrared, burn wound healing, autophagy NLRP3 inflammasome

Organism: Rat

Tissue: Skin

Pathological State: Burn Wound

517
Serum Autoantibodies in Chronic Prostate Inflammation in Prostate Cancer Patients

Bettina Schlick, Petra Massoner, Angelika Lueking, Pornpimol Charoentong, Mirjam Blattner, Georg Schaefer, Klaus Marquart, Carmen Theek, Peter Amersdorfer, Dirk Zielinski, Matthias Kirchner, Zlatko Trajanoski, Mark A. Rubin, Stefan Müllner, Peter Schulz-K

PLOS ONE (PLOS) Austria, 10 February 2016

Oncology

Key words:Prostate cancer, autoantibodies, inflammation, prostate gland, inflammatory diseases, microarrays, prostate diseases, radical prostatectomy

Organism: Human

Tissue: Prostate

Pathological State: Cancer

518
Acquisition of tumorigenic potential and enhancement of angiogenesis in pulmonary stem/progenitor cells through Oct-4 hyperexpression

SY Gu, CC Ho, YK Huang, HW Chen, YC Wang…

Oncotarget (NCBI) Taiwan, 09 February 2016

Oncology

Key words:pulmonary stem/progenitor cells, cancer initiating cells, Oct-4, angiogenesis, angiopoietins/Tie2

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

519
MINI ORAL SESSIONS (MINI38.12 Multiplex Immunofluorescence Identifies Differences in Immune Microenvironment & Prognostic Biomarkers between Mesothelioma Subtypes)

Tanguy Seiwert, Stephanie Mcgregor, Chengyi Shu, Igor Feldman, Tong Zi, Zhixiang Zuo, Arun Khattri, Aliya Husain, Hadi Duraid, Wickii T. Vigneswaran,Thomas N. Krausz, Sriram Sathyanarayanan, Hedy Lee Kindle

Journal of Thoracic Oncology (Elsevier) USA, 05 February 2016

Oncology

Key words:Multiplex immunofluorescence, immmune microenvironment, biomarkers, mesothelioma

Organism: Human

Tissue: Mesothelium

Pathological State: Cancer

520
Oxytocin promotes functional coupling between paraventricular nucleus and both sympathetic and parasympathetic cardioregulatory nuclei

Jason R. Yee, William M. Kenkel, Jessie L. Frijling, Sonam Dodhia, Kenneth G. Onishi, Santiago Tovar, Maha J. Saber, Gregory F. Lewis, Wensheng Liu, Stephen W. Porges C. Sue Carter

Hormones and Behavior (Elsevier) USA, 04 February 2016

Endocrinology

Key words:Oxytocin, functional coupling, paraventricular nucleus, cardioregulatory nuclei

Organism: Mouse

Tissue: Brain

521
Characterizing Villitis of Unknown Etiology and Inflammation in Stillbirth

Hayley Derricott, Rebecca L. Jones, Susan L. Greenwood, Gauri Batra, Margaret J. Evans, Alexander E.P. Heazell

The American Journal of Pathology (Elsevier) UK, 03 February 2016

Reproductive Medicine

Key words:Villitis, inflammation, stillbirth

Organism: Human

Tissue: Placenta

Pathological State: Villitis 

522
Prevention of SHIV transmission by topical IFN-β treatment

RS Veazey, HA Pilch-Cooper, TJ Hope, G Alter, AM Carias, M Sips, X Wang, B Rodriguez, SF Sieg, A Reich, P Wilkinson, MJ Cameron & MM Lederman

Mucosal Immunology (Nature) USA, 03 February 2016

Virology

Key words:Drug therapy, HIV infections, Mucosal immunology, Viral transmission

Organism: Monkey

Tissue: Uterus

Pathological State: Virus Infection

523
Infiltration of lymphocyte subpopulations into cancer microtissues as a tool for the exploration of immunomodulatory agents and biomarkers

Stefan Koeck , Marit Zwierzina, Julia M. Huber, Mario Bitsche, Edith Lorenz, Gabriele Gamerith, Jozsef Dudas, Jens M. Kelm, Heinz Zwierzina, Arno Amann

Immunobiology (Elsevier) Austria, Switzerland, 01 February 2016

Immunology

Key words:3D, biomarker, co-culture, cancer, immune cells, infiltration, subpopulation

Organism: Human

Pathological State: Cancer

Cell Line: A549, Colo699, Calu-6 cells (human non-small-cell lung cancer cells)

524
Treatment Regimen, Surgical Outcome, and T-cell Differentiation Influence Prognostic Benefit of Tumor-Infiltrating Lymphocytes in High-Grade Serous Ovarian Cancer

Maartje C.A. Wouters, Fenne L. Komdeur1, Hagma H. Workel, Harry G. Klip, Annechien Plat, Neeltje M. Kooi, G. Bea A. Wisman, Marian J.E. Mourits, Henriette J.G. Arts, Maaike H.M. Oonk, Refika Yigit, Steven de Jong, Cornelis J.M. Melief, Harry Hollema, Evel

Clinical Cancer Research (High Wire) The Netherlands, 01 February 2016

Oncology

Key words:T-cell diferentiation, tumor-infiltrating lymphocytes, serous ovarian cancer

Organism: Human

Tissue: Ovaries

Pathological State: Cancer

525
FGF2 inhibits endothelial–mesenchymal transition through microRNA-20a-mediated repression of canonical TGF-ß signaling

Ana C. P. Correia, Jan-Renier A. J. Moonen, Marja G. L. Brinker, Guido Krenning

Journal of Cell Science (The Company of Biologists) The Netherlands, 01 February 2016

Cell Biology

Key words:Endothelial–mesenchymal transition, microRNA-20a-mediated repression, canonical TGF-β signaling

Organism: Human

Cell Line: HUVECs(Human umbilical vein endothelial cells)

526
Injectable extracellular matrix hydrogels as scaffolds for spinal cord injury repair

Dmitry Tukmachev, Serhiy Forostyak, Zuzana Koci, Kristyna Zaviskova, Irena Vackova, Karel Vyborny, Ioanna Sandvig, Axel Sandvig, Christopher J. Medberry, Stephen F. Badylak, Eva Sykova, and Sarka Kubinova

Tissue Engineering A (Mary Ann Libert) Czech Republic, Norway, UK, Sweden, USA, 28 January 2016

Tissue Engineering

Key words:spinal cord injury; hydrogel; extracellular matrix; scaffold; tissue engineering; stem cells

Organism: Rat

Tissue: Spinal Cord

Pathological State: Spinal Cord Injury

527
Amelioration of Experimental Autoimmune Arthritis Through Targeting of Synovial Fibroblasts by Intraarticular Delivery of MicroRNAs 140-3p and 140-5p

Jia-Shiou Peng, Shih-Yao Chen, Chao-Liang Wu, Hao-Earn Chong, Yun-Chiao Ding, Ai-Li Shiau, Chrong-Reen Wang

Arthritis & Rheumatology (Wiley) Taiwan, 25 January 2016

Rheumatology

Key words:Autoimmune arthritis, synovial fibroblasts, MicroRNAs

Organism: Mouse

Tissue: Joint

Pathological State: Rheumatoid Arthritis

528
Fumaric acid esters promote neuronal survival upon ischemic stress through activation of the Nrf2 but not HIF-1 signaling pathway

Jiemeng Lin-Holderer, Lexiao Li, Daniel Gruneberg, Hugo H. Marti, Reiner Kunze

Neuropharmacology (Elsevier) Germany, 19 January 2016

Neuroscience

Key words:Dimethyl fumarate, monomethyl fumarate, fumaric acid esters, Nrf2, HIF, ischemia

Organism: Mouse

Tissue: Brain

529
Energy landscapes and functions of supramolecular systems

Faifan Tantakitti, Job Boekhoven, Xin Wang, Roman V. Kazantsev, Tao Yu, Jiahe Li, Ellen Zhuang, Roya Zandi, Julia H. Ortony, Christina J. Newcomb, Liam C. Palmer, Gajendra S. Shekhawat, Monica Olvera de la Cruz, George C. Schatz & Samuel I. Stupp

Nature materials (Nature) USA, 18 January 2016

Biological Materials

Key words:Bioinspired materials, Materials science

Organism: Mouse

Cell Line: C2C12 mouse pre-myoblasts

530
Software-assisted morphometric and phenotype analyses of human peripheral blood monocyte-derived macrophages induced by a microenvironment model of human esophageal squamous cell carcinoma

Mari Nishio, Naoki Urakawa, Manabu Shigeoka, Nobuhisa Takase, Yumi Ichihara, Noriaki Arai, Yu-ichiro Koma, Hiroshi Yokozaki

Pathology International (Wiley) Japan, 18 January 2016

Pathology

Key words:Esophageal cancer, image analysis, macrophages, tumor microenvironment

Organism: Human

Cell Line: PBMCs (Peripheral blood mononuclear cells )

531
Towards personalised treatment in primary Sjögren's syndrome: baseline parotid histopathology predicts responsiveness to rituximab treatment

Konstantina Delli, Erlin A Haacke, Frans G M Kroese, Rodney P Pollard, Stephan Ihrler, Bert van der Vegt, Arjan Vissink, Hendrika Bootsma, Frederik K L Spijkervet

Annals of the Rheumatic Diseases (High Wire) The Netherlands, Germany, 15 January 2016

Rheumatology

Key words:Sjögren's syndrome, parotid histopathology, responsiveness to rituximab treatment

Organism: Human

Tissue: Parotid Gland

Pathological State: Sjögren's Syndrome

532
Low birth weight associates with hippocampal gene expression

J.P. Buschdorf, M.L. Ong, S.X. Ong, J.L. MacIsaac, K. Chng, M.S. Kobor, M.J. Meaney, J.D. Holbrook

Neuroscience (Elsevier) Singapore, Canada, 12 January 2016

Neuroscience

Key words:Low birth weight, hippocampus, DNA methylation, mental disorders, microarray

Organism: Monkey

Tissue: Brain

533
Inhibition of Aerobic Glycolysis Attenuates Disease Progression in Polycystic Kidney Disease

Meliana Riwanto, Sarika Kapoor, Daniel Rodriguez, Ilka Edenhofer, Stephan Segerer, Rudolf P. Wüthrich

PLOS ONE (PLOS) Switzerland, 11 January 2016

Nephrology

Key words:Kidneys, glycolysis, renal system, epithelial cells, glucose metabolism, apoptosis, ERK signaling cascade, polycystic kidney disease

Organism: Rat

Tissue: Kidney

Pathological State: Polycystic Kidney Disease

534
Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer

Leila Akkari, Vasilena Gocheva, Marsha L. Quick, Jemila C. Kester, Alison K. Spencer, Alfred L. Garfall, Robert L. Bowman, Johanna A. Joyce

Genes & Development (CHS Press) USA, Switzerland, 10 January 2016

Oncology

Key words:Cathepsin protease, compensatory mechanism, cancer

Organism: Mouse

Tissue: Pancreas

Pathological State: Cancer

535
Toll-Like Receptor 4 Is Essential in the Development of Abdominal Aortic Aneurysm

Chao-Han Lai, Kuan-Chieh Wang, Fang-Tzu Lee, Hung-Wen Tsai, Chih-Yuan Ma, Tsung-Lin Cheng, Bi-Ing Chang, Yu-Jen Yang, Guey-Yueh Shi, Hua-Lin Wu

PLOS ONE (PLOS) Taiwan, 07 January 2016

Immunology

Key words:Macrophages, immune receptor signaling, aneurysms, inflammation, toll-like receptors, aorta, small interfering RNAs, cytokines

Organism: Mouse

Tissue: Kidney

536
The single-chain anti-TNF-a antibody DLX105 induces clinical and biomarker responses upon local administration in patients with chronic plaque-type psoriasis

Athanasios Tsianakas, Patrick M. Brunner, Kamran Ghoreschi, Claudia Berger, Karin Loser, Martin Röcken, Georg Stingl, Thomas Luger, Thomas Jung

Experimental Dermatology (Wiley) Germany, Austria, Switzerland, 06 January 2016

Dermatology

Key words:Psoriasis, TNF-alpha, TNF-alpha-blocker

Organism: Human

Tissue: Skin

Pathological State: Psoriasis

537
3, 4-Dihydroxy-L-phenylalanine as a novel covalent linker of extracellular matrix proteins to polyacrylamide hydrogels with a tunable stiffness

Olaf Y. Wouters, Diana T.A. Ploeger, Sander M. van Putten, and Ruud A. Bank

Tissue Engineering Part C (Mary Ann Libert) The Netherlands, 05 January 2016

Tissue Engineering

Key words:Tissue Enigneering, 3,4-Dihydroxy-L-Phenylalanine, Linker, Extracellular Matrix, Hydrogel, Stiffness

Organism: Human

Cell Line: human dermal fetal fibroblasts

538
T1 Mapping by CMR Imaging : From Histological Validation to Clinical Implication

Andreas A. Kammerlander, Beatrice A. Marzluf, Caroline Zotter-Tufaro, Stefan Aschaue, Franz Duca, Alina Bachman, Klaus Knechtelsdorfer, Matthias Wiesinger, Stefan Pfaffenberge, Andreas Greiser Irene M. Lang, Diana Bonderman, Julia Mascherbauer

JACC: Cardiovascular Imaging (Elsevier) Austria, Germany, 01 January 2016

Cardiology

Key words:CMR imaging, histological validation

Organism: Human

Tissue: Heart

539
N-octanoyl dopamine attenuates the development of transplant vasculopathy in rat aortic allografts via smooth muscle cell protective mechanisms

J Wedel, MC Hottenrott, M Bulthuis, S Huitema, BA Yard, JK Hillebrands

Transplantation (Wolters Kluwer) The Netherlands, Germany, 01 January 2016

Transplantation Medicine

Key words:N-octanoyl Dopamine, Transplant Vasculopathy, Aortic Allografts, Smooth Muscle Cells, Protective Mechanisms

Organism: Rat

Tissue: Blood Vessels

540
The anti-inflammatory compound curcumin enhances locomotor and sensory recovery after spinal cord injury in rats by immunomodulation

Lucia Machova Urdzikova , Kristyna Karova , Jiri Ruzicka , Anna Kloudova , Craig Shannon , Jana Dubisova , Raj Murali , Sarka Kubinova , Eva Sykova , Meena Jhanwar-Uniyal and Pavla Jendelova

International Journal of Molecular Sciences (MDPI) Czech Republic, USA, 31 December 2015

Neuroscience

Key words:spinal cord injury; curcumin; inflammation; cytokines; secondary processes; NF-κB

Organism: Rat

Tissue: Spinal Cord

Pathological State: Spinal Cord Injury

541
Mercury toxicokinetics of the healthy human term placenta involve amino acid transporters and ABC transporters

Elisabeth Strak, Isabella Ellinger, Christina Balthasar, Matthias Scheinast, Jasmin Schatz, Tamara Szattler, Sonja Bleichert, Leila Saleh, Martin Knöfler, Harald Zeisler, Markus Hengstschläger, Margit Rosner, Hans Salzer, Claudia Gundacker

Toxicology (Elsevier) Austria, 29 December 2015

Toxicology

Key words:Mercury, placenta, amino acid transporters

Organism: Human

Tissue: Placenta

542
Long-Term In Vitro Expansion of Salivary Gland Stem Cells Driven by Wnt Signals

Martti Maimets, Cecilia Rocchi, Reinier Bron, Sarah Pringle, Jeroen Kuipers, Ben N.G. Giepmans, Robert G.J. Vries, Hans Clevers, Gerald de Haan, Ronald van Os, Robert P. Coppes

Stem Cell Reports (Elsevier) The Netherlands, 24 December 2015

Stem Cell Research

Key words:Stem cells, in vitro expansion, wnt signals

Organism: Human

Tissue: Salivary Gland

543
Long-term in vitro expansion of salivary gland stem cells driven by Wnt signals

Martti Maimets, Cecilia Rocchi, Reinier Bron, Sarah Pringle, Jeroen Kuipers, Ben N.G. Giepmans, Robert G.J. Vries, Hans Clevers, Gerald de Haan, Ronald van Os, Robert P. Coppes

Stem Cell Reports (Elsevier) The Netherlands, 24 December 2015

Stem Cell Research

Key words:In Vitro Expansion, Salivary Gland, Stem Cells, Wnt

Organism: Mouse

Tissue: Salivary Gland

544
Co-culture of placental explants with isolated CD4 and CD8 T cells: a functional model to define the consequences of placental inflammation

Hayley Derricott, Rebecca L. Jones, Alexander E.P. Heazell, Susan L. Greenwood

Journal of Biological Methods () UK, 22 December 2015

Reproductive Medicine

Key words:inflammation, placenta, T lymphocytes, villitis, VUE

Organism: Human

Cell Line: placental T-cells

545
Mycolic acid-specific T cells protect against Mycobacterium tuberculosis infection in a humanized transgenic mouse model

J Zhao, S Siddiqui, S Shang, Y Bian, S Bagchi, Y He, CR Wang

eLife (eLife Sciences Publications) USA, 10 December 2015

Microbiology

Key words:Mycolic acid-specific T cells, Mycobacterium tuberculosis, humanized transgenic mouse model

Organism: Mouse

Tissue: Lung

Pathological State: Bacterial Infection

546
Reproductive periodicity, spawning induction, and larval metamorphosis of the hemichordate acorn worm Ptychodera flava

Ching-Yi Lin, Che-Huang Tung, Jr-Kai Yu, Yi-Hsien Su

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution (Wiley) Taiwan, 10 December 2015

Zoology

Key words:Reproductive periodicity, larval metamorphosis, hemichordate

Organism: Acorn worm

Tissue: Penis

547
Low Hodgkin/Reed-Sternberg Cell Density Assessed with Automated Image Analysis Is a Poor Prognostic Factor in Classic Hodgkin Lymphoma Patients

Vit Prochazka, Tereza Dyskova, Zuzana Prouzova, Tomas Papajik, Jiri Minarik, Juraj Duras, Jozef Michalka, Alice Sykorova, Peter Mikula, Ludek Raida and Eva Kriegova

Blood (American Society of Hematology) Czech Republic, 03 December 2015

Oncology

Key words:Cell Density, Automated Image Analysis, Prognostic Factor, Hodgkin Lymphoma

Organism: Human

Tissue: Lymphoid Tissue

Pathological State: Cancer

548
Quantitative Analysis of Tissue Inflammation and Responses to Treatment in Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked (IPEX) Syndrome and Review of Literature

Chih-An Chen, Wan-Chen Chung, Yuan-Yow Chiou, Yao-Jong Yang, Yung-Chieh Lin, Hans D. Ochs, Dr. Chi-Chang Shieh

Journal of Microbiology, Immunology and Infection (Elsevier) Taiwan, USA, 01 December 2015

Immunology, Microbiology

Key words:Immune dysregulation, polyendocrinopathy, enteropathy, X-Linked (IPEX) syndrome, regulatory T cells, T helper 2 cells

Organism: Human

Tissue: Small Intestine

Pathological State: Endocrinopathy, Enteropathy, X-linked syndrome

549
Hirsutella sinensis mycelium attenuates bleomycin-induced pulmonary inflammation and fibrosis in vivo

TT Huang, HC Lai, YF Ko, DM Ojcius, YW Lan, J Martel, JD Young,

J Cancer Treat Diagnosis (nature.com) Taiwan, USA, 26 November 2015

Microbiology

Key words:Drug development, Inflammasome

Organism: Human

Tissue: Lung

Pathological State: Inflammation, Fibrosis

550
Dynamic Trk and G Protein Signalings Regulate Dopaminergic Neurodifferentiation in Human Trophoblast Stem Cells

Eing-Mei Tsai, Yu-Chih Wang, Tony Tung-Yin Lee, Cheng-Fang Tsai, Hung-Sheng Chen, Feng-Jie Lai, Kazunari K. Yokoyama, Tsung-Hsun Hsieh, Ruey-Meei Wu, Jau-nan Lee

PLOS ONE (PLOS) Taiwan, USA, 25 November 2015

Neuroscience

Key words:Neurons, DNA transcription, G-protein signaling, stem cells, genomic signal processing, retinoic acid signaling cascade, retinoid signaling, neuronal differentiation

Organism: Human

Cell Line: hTS cells

551
Alpha-Actinin 4 Is Associated with Cancer Cell Motility and Is a Potential Biomarker in Non–Small Cell Lung Cancer

MC Wang, YH Chang, CC Wu, YC Tyan, HC Chang, YG Goan, WW Lai, PN Cheng, PC Liao

Journal of Thoracic Oncology (Elsevier) Taiwan, 20 November 2015

Oncology

Key words:ACTN4, non–small-cell lung cancers, CL1-0 and CL1-5 cell lines, siRNA

Organism: Human

Tissue: Lung

Pathological State: Cancer

552
Curcumin Suppresses Phthalate-Induced Metastasis and the Proportion of Cancer Stem Cell (CSC)-like Cells via the Inhibition of AhR/ERK/SK1 Signaling in Hepatocellular Carcinoma

Cheng-Fang Tsai, Tsung-Hua Hsieh, Jau-Nan Lee, Chia-Yi Hsu, Yu-Chih Wang, Kung-Kai Kuo, Hua-Lin Wu, Chien-Chih Chiu, Eing-Mei Tsa, and Po-Lin Kuo

Journal of Agricultural Food Chemistry (ACS Publications) Taiwan, 20 November 2015

Oncology

Key words:Phthalate, curcumin, hepatocellular carcinoma, metastasis, side population, cancer stem cells

Organism: Mouse

Tissue: Liver, Lung

553
MiR-125b is critical for fibroblast-to-myofibroblast transition and cardiac fibrosis

Varun Nagpal , Rahul Rai , Aaron T. Place , Sheila B. Murphy , Suresh K. Verma , Asish K. Ghosh , and Douglas E. Vaughan

Circulation (AHA Journals) USA, 19 November 2015

Cardiology

Key words:RNA sequence, fibrosis, angiotensin II, transforming growth factor, miR-125b

Organism: Mouse

Tissue: Heart

Pathological State: Fibrosis

554
IMPS-11 Expression and prognostic impact of immune modulatory molecule PD-L1 in meningioma

S Han, G Reis, G Kohanbash, S Srivastav…

Neuro-Oncology (Oxford Journals) USA, 09 November 2015

Oncology

Key words:meningioma, patient prognosis, impact, molecule, programmed cell death 1 ligand 1

Organism: Human

Tissue: Brain

Pathological State: Cancer

555
CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow

A Nakamura-Ishizu, K Takubo, H Kobayashi, K Suzuki-Inoue, T Suda

Journal of Experimental Medicine (Rockefeller University Press) Japan, 09 November 2015

Stem Cell Research

Key words:CLEC-2, megakaryocyte, hematopoietic stem cells, bone marrow

Organism: Mouse

Tissue: Bone Marrow

556
Transdermal drug targeting and functional imaging of tumor blood vessels in the mouse auricle

H Schröder, D Komljenovic, M Hecker, T Korff

The FASEB Journal (FASEB) Germany, 06 November 2015

Oncology

Key words:angiogenesis • blood vessel growth • bortezomib • mouse model • perfusion

Organism: Mouse

Tissue: Ear

Pathological State: Cancer

557
Melanin pigmentation in rat eyes: in vivo imaging by polarization-sensitive optical coherence tomography and comparison to histology

B Baumann, J Schirmer, S Rauscher…

Investigative Ophthalmology & Visual Science (ARVO Journals) Austria, 01 November 2015

Ophthalmology

Key words:Melanin Pigmentation, Eyes, In Vivo Imaging, Polarization-Sensitive Optical Coherence Tomography

Organism: Rat

Tissue: Eye

558
Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-a Production in Women

Morgane Griesbeck, Susanne Ziegler, Sophie Laffont, Nikaïa Smith, Lise Chauveau, Phillip Tomezsko, Armon Sharei, Georgio Kourjian, Filippos Porichis, Meghan Hart, Christine D. Palmer, Michael Sirignano, Claudia Beisel, Heike Hildebrandt, Claire Cénac, Ale

Journal of Immunology (AAI) France, Germany, UK, Australia, 30 October 2015

Immunology

Key words:Plasmacytoid dendridic cell levels, IRF5

Organism: Human, Mouse

Cell Line: PBMCs (Peripheral blood mononuclear cells )

559
Astrocytic CCAAT/Enhancer-Binding Protein Delta Contributes to Glial Scar Formation and Impairs Functional Recovery After Spinal Cord Injury

Shao-Ming Wang, Jung-Yu C. Hsu, Chiung-Yuan Ko, Nai-En Chiu, Wai-Ming Kan, Ming-Derg Lai, Ju-Ming Wang

Molecular Neurobiology (Springer) Taiwan, 28 October 2015

Neuroscience

Key words:Astrogliosis C/EBPd, MMP-3 RhoA, astrocyte migration

Organism: Mouse

Tissue: Spinal Cord

Pathological State: Spinal Cord Injury

560
Novel p53-dependent anticancer strategy by targeting iron signaling and BNIP3L-induced mitophagy

Nastasia Wilfinger, Shane Austin, Barbara Scheiber-Mojdehkar, Walter Berger, Siegfried Reipert, Monika Praschberger, Jakob Paur, Robert Trondl, Bernhard K. Keppler, Christoph C. Zielinski, and Karin Nowikovsky

Oncotarget (NCBI) Austria, 26 October 2015

Oncology

Key words:cancer, p53, BNIP3L, mitophagy, gallium complex

Organism: Human

Pathological State: Cancer

Cell Line: Human colon carcinoma cells

561
Quantitative Image Analysis of Epithelial and Stromal Area in Histological Sections of Colorectal Cancer: An Emerging Diagnostic Tool.

R. Rogojanu, T. Thalhammer, U. Thiem, A. Heindl, I. Mesteri, A. Seewald, W. Jäger, C. Smochina, I. Ellinger, G. Bises

Biomed Research International (Hindawi Publishing Corporation) Austria, Romania, 22 October 2015

Oncology

Key words:Image analysis, histology, colorectal cancer, diagnosis tool

Organism: Human

Tissue: Colon

Pathological State: Cancer

562
Glucose-regulated protein 94 mediates cancer progression via AKT and eNOS in hepatocellular carcinoma

Chien-Yu Huang, Uyanga Batzorig, Wan-Li Cheng, Ming-Te Huang, Wei- Yu Chen, Po-Li Wei, Yu-Jia Chang

Tumor Biology (Springer) Taiwan, Mongolia, 22 October 2015

Oncology

Key words:GRP94 HCC eNOS AKT Proliferation

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

563
An Emerging Approach for Parallel Quantification of Intracellular Protozoan Parasites and Host Cell Characterization Using TissueFAXS Cytometry

Maximilian Schmid, Bianca Dufner, Julius Dürk, Konstanze Bedal, Kristina Stricker, Lukas Ali Prokoph, Christoph Koch, Anja K. Wege, Henner Zirpel, Ger van Zandbergen, Rupert Ecker, Bogdan Boghiu, Uwe Ritter

PLOS ONE (PLOS) Germany, Austria, 21 October 2015

Parasitology

Key words:Macrophages, parasitic diseases, host cells, leishmania major, DAPI staining, cell staining, host-pathogen interactions, intracellular pathogens

Organism: Mouse

Pathological State: Parasitic Infection

Cell Line: Makrophages

564
Redox Regulation of Pro-IL-1β Processing May Contribute to the Increased Severity of Serum-Induced Arthritis in NOX2-Deficient Mice

Ya-Fang Huang, Pei-Chi Lo, Chia-Liang Yen, Peter Andrija Nigrovic, Wen-Chen Chao, Wei-Zhi Wang, George Chengkang Hsu, Yau-Sheng Tsai, and Chi-Chang Shieh

Antioxidants & Redox Signaling (Mary Ann Libert) Taiwan, USA, 21 October 2015

Rheumatology

Key words:Redox Regulation,Pro-IL-1β,Serum-Induced Arthritis, NOX2

Organism: Mouse

Tissue: Joint

Pathological State: Rheumatoid Arthritis

565
Development of recombinant collagen-peptide-based vehicles for delivery of adipose-derived stromal cells (ADSC)

M. Parvizi, J.A. Plantinga, C. van Spreuwel-Goossens, S. van Dongen, S. G. Kluijtmans, M.C. Harmsen

Journal of Biomedical Materials Research Part A (Wiley) The Netherlands, 14 October 2015

Biological Materials

Key words:Recombinant-Collagen Microspheres, integrin binding motives, crosslinked, ADSC, delivery

Organism: Human

Cell Line: Adipose tissue derived stromal cells (ADSC)

566
Cardioprotective Actions of TGFßRI Inhibition Through Stimulating Autocrine/Paracrine of Survivin and Inhibiting Wnt in Cardiac Progenitors

Yu-Sian Ho, Wan-Hsuan Tsai, Fen-Chiung Lin, Wei-Pang Huang, Lung-Chun Lin, Sean M. Wu, Yu-Ru Liu, Wen-Pin Chen

Stem Cells (Wiley) Taiwan, USA, 10 October 2015

Stem Cell Research

Key words:Nkx2.5, sca1, Birc5, survivin, MEK/ERK, Wnt3a

Organism: Mouse

Tissue: Heart

Pathological State: Fibrosis

567
YAP1 Is a Driver of Myofibroblast Differentiation in Normal and Diseased Fibroblasts

Bram Piersma, Saskia de Rond, Paul M.N. Werker, Stellar Boo, Boris Hinz, Marike M. van Beuge, Ruud A. Bank

The American Journal of Pathology (Elsevier) The Netherlands, Canada, 10 October 2015

Pathology

Key words:Myofibroblast, fibroblasts, YAP 1

Organism: Human

Pathological State: Dupuytren's Disease

Cell Line: Dermal fibroblasts

568
The pro-fibrotic properties of transforming growth factor on human fibroblasts are counteracted by caffeic acid by inhibiting myofibroblast formation and collagen synthesis

Masum M. Mia, Ruud A. Bank

Cell and Tissue Research (Springer) The Netherlands, 09 October 2015

Cell Biology

Key words:Fibrosis, collagen, myofibroblasts, caffeic acid, lysyl hydroxylase

Organism: Human

Cell Line: HDFa and HLFa Fibroblasts

569
Characterization of sulfur mustard resistant keratinocyte cell line HaCaT/SM

Wolf Markus, Siegert Markus, Rothmiller Simone, Scheithauer Nina, Strobelt Romano, Steinritz Dirk, Thiermann Horst, Schmidt Annette

Toxicology Letters (Elsevier) Germany, 09 October 2015

Toxicology

Key words:Sulfur mustard, resistance, keratinocytes

Organism: Human

Cell Line: HaCaTs (human keratinocyte cell line )

570
Synergy of endothelial and neural progenitor cells from adipose-derived stem cells to preserve neurovascular structures in rat hypoxic-ischemic brain injury

Yuan-Yu Hsueh, Ya-Ju Chang, Chia-Wei Huang, Fitri Handayani, Yi-Lun Chiang, Shih-Chen Fan, Chien-Jung Ho, Yu-Min Kuo, Shang-Hsun Yang, Yuh-Ling Chen, Sheng-Che Lin, Chao-Ching Huang & Chia-Ching Wu

Scientific reports (Nature) Taiwan, 08 October 2015

Neuroscience

Key words:Neural progenitors, stem cells, brain injury

Organism: Rat

Tissue: Brain

Pathological State: Cerebral Ischemia

571
Sympathetic Neurotransmitters Modulate Osteoclastogenesis and Osteoclast Activity in the Context of Collagen-Induced Arthritis

Dominique Muschter, Nicole Schäfer, Hubert Stangl, Rainer H. Straub, Susanne Grässel

PLOS ONE (PLOS) Germany, 02 October 2015

Rheumatology

Key words:Osteoclasts, neurotransmitters, arthritis, macrophages, apoptosis, gene expression, adenylyl cyclase, immune receptors

Organism: Human

Pathological State: Cancer

Cell Line: SAOS–2 cells

572
Intestinal Epithelial Cell Tyrosine Kinase 2 Transduces IL-22 Signals To Protect from Acute Colitis

Eva Hainzl, Silvia Stockinger, Isabella Rauch, Susanne Heider, David Berry, Caroline Lassni, Clarissa Schwab, Felix Rosebrock, Gabriel Milinovich, Michaela Schlederer, Michael Wagner, Christa Schleper, Alexander Loy, Tim Urich, Lukas Kenner, Xiaonan Han,

The Journal of Immunology (AAI) Austria, USA, 02 October 2015

Gastroenterology

Key words:Intestinal epithelial cell, acute colitis

Organism: Mouse

Tissue: Colon

Pathological State: Colitis

573
Putative Prostate Cancer Risk SNP in an AR Binding Site of the Melanophilin Gene Illustrates Enrichment of Risk SNPs in AR Target Sites

Huajie Bu, Narisu Narisu, Bettina Schlick, Johannes Rainer, Thomas Manke, Georg Schäfer, Lorenza Pasqualini, Peter Chines, Michal R. Schweiger, Christian Fuchsberger, Helmut Klocker

Human Mutation (Wiley) Austria, Germany, Italy, USA, 28 September 2015

Oncology

Key words:Prostate cancer, risk SNPs, androgen receptor, melanophilin, MLPH;androgen regulation, AR

Organism: Human

Tissue: Prostate

Pathological State: Cancer

574
The decrease in histone methyltransferase EZH2 in response to fluid shear stress alters endothelial gene expression and promotes quiescence

Monika Maleszewska, Byambasuren Vanchin, Martin C. Harmsen, Guido Krenning

Angiogenesis (Springer) The Netherlands, Germany, 28 September 2015

Cell Biology

Key words:Endothelial cell, enhancer of zeste homolog-2 (EZH2), fluid shear stress (FSS), mechanotransduction, chromatin

Organism: Human

Cell Line: HUVECs (Human umbilical vein endothelial cells)

575
A sunblock based on bioadhesive nanoparticles

Y Deng, A Ediriwickrema, F Yang, J Lewis, M Girardi…

British Journal of … (nature.com) , 28 September 2015

576
Amelioration of Chemotherapy-Induced Intestinal Mucositis by Orally Administered Probiotics in a Mouse Model

Chun-Yan Yeung , Wai-Tao Chan , Chun-Bin Jiang, Mei-Lien Cheng, Chia-Yuan Liu, Szu-Wen Chang, Jen-Shiu Chiang Chiau, Hung-Chang Lee

PLOS ONE (PLOS) Taiwan, 25 September 2015

Oncology

Key words:Probiotics, gastrointestinal tract, diarrhea, mouse models, cytokines, jejunum, lactobacillus, cancer treatment

Organism: Mouse

Tissue: Small Intestine

Pathological State: Mucositis

577
The great escape: Pseudomonas breaks out of the lung

A Zhang, SM Rangel, AR Hauser

Microbial Cell (NCBI) USA, 23 September 2015

Microbiology

Key words:Pseudomonas aeruginosa, ExoS, pneumonia, dissemination

Organism: Mouse

Tissue: Lung

Pathological State: Bacterial Infection

578
Type 3 innate lymphoid cells maintain intestinal epithelial stem cells after tissue damage

Patricia Aparicio-Domingo, Monica Romera-Hernandez, Julien J. Karrich, Ferry Cornelissen, Natalie Papazian, Dicky J. Lindenbergh-Kortleve, James A. Butler, Louis Boon, Mark C. Coles, Janneke N. Samsom, Tom Cupedo

Journal of Experimental Medicine (Rockefeller University Press) The Netherlands, UK, 21 September 2015

Stem Cell Research

Key words:Type 3 innate lymphoid cells, intestinal epithelial stem cells, tissue damage

Organism: Mouse

Tissue: Small Intestine, Colon

579
Bone marrow micro-environmental CD4+ and CD8+ lymphocyte infiltration patterns define overall- and progression free survival in standard risk Multiple Myeloma – an analysis from the Austrian Myeloma Registry

Wolfgang Willenbacher, Ella Willenbacher, Claudia Zelle-Rieser, Rainer Biedermann, Roman Weger, Karin Jöhrer, Andrea Brunner

Leukemia & Lymphoma (Taylor & Francis) Austria, 19 September 2015

Oncology

Key words:Bone marrow, lymphocite infiltration, myeloma

Organism: Human

Tissue: Bone

Pathological State: Cancer

580
Nuclear HDAC6 inhibits invasion by suppressing NF-κB/MMP2 and is inversely correlated with metastasis of non-small cell lung cancer

CJ Yang, YP Liu, HY Dai, YL Shiue, CJ Tsai…

Oncotarget (NCBI) Taiwan, 15 September 2015

Oncology

Key words:HDAC6, NF-κB, MMP2, metastasis, lung cancer

Organism: Human

Tissue: Lung

Pathological State: Cancer

581
Quantitative functional MRI in a clinical orthotopic model of pancreatic cancer in immunocompetent Lewis rats

Zhuoli Zhang, Linfeng Zheng, Weiguo Li, Andrew C Gordon, Yi Huan, Junjie Shangguan, Daniel Procissi, David J Bentrem, Andrew C Larson

American Journal of Translational Research (e-Century Publishing Corporation) USA, China, 15 September 2015

Oncology

Key words:Magnetic resonance imaging, imaging biomarker, pancreatic cancer, immunocompetent Lewis rats

Organism: Rat

Tissue: Pancreas

Pathological State: Cancer

582
Sulfur and nitrogen mustards induce characteristic poly(ADP-ribosyl)ation responses in HaCaT keratinocytes with distinctive cellular consequences

Aswin Mangerich, Malgorzata Debiak, Matthias Birtel, Viviane Ponath, Frank Balszuweit, Kirsten Lex, Rita Martello, Waltraud Burckhardt-Boer, Romano Strobelt, Markus Siegert, Horst Thiermanb, Dirk Steinritz, Annette Schmidt, Alexander Bürkle

Toxicology Letters (Elsevier) Germany, 14 September 2015

Toxicology

Key words:Poly(ADP-ribose), PARP inhibitors, sulfur mustard, nitrogen mustard, genotoxicity, HaCaT, mass spectrometry, micronucleus

Organism: Human

Cell Line: HaCaTs (human keratinocyte cell line )

583
Efficient therapy of ischaemic lesions with VEGF121-fibrin in an animal model of systemic sclerosis.

Allipour Birgani S, Mailänder M, Wasle I, Dietrich H, Gruber J, Distler O, Sgonc R

Annals of the Rheumatic Diseases (BMJ) Austria, Switzerland, 11 September 2015

Rheumatology

Key words:Outcomes research, systemic sclerosis, treatment

Organism: Chicken

Tissue: Skin

Pathological State: Systemic Sclerosis

584
The ß-catenin signaling pathway induces aggressive potential in breast cancer by up-regulating the chemokine CCL5

Rika Yasuhara, Tarou Irié, Kenya Suzuki, Terumasa Sawada, Noriko Miwa, Akiko Sasaki, Yuko Tsunoda, Seigo Nakamura, Kenji Mishima

Experimental Cell Research (Elsevier) Japan, 10 September 2015

Oncology

Key words:ß-Catenin, metastasis, breast cancer, cytokines, CCL5

Organism: Human

Tissue: Breast

Pathological State: Cancer

585
Sur8/Shoc2 promotes cell motility and metastasis through activation of Ras-PI3K signaling

S Kaduwal, WJ Jeong, JC Park, KH Lee, YM Lee, SH Jeon, YB Lim, DS Min, KY Choi

Oncotarget (NCBI) South Korea, 05 September 2015

Oncology

Key words:Sur8, Ras, PI3K, cell migration, metastasis

Organism: Human

Tissue: Skin

Pathological State: Cancer

586
The IκB kinase inhibitor ACHP strongly attenuates TGF β1‐induced myofibroblast formation and collagen synthesis

Masum M. Mia, Ruud A. Bank

Journal of Cellular and Molecular Medicine (Wiley) The Netherlands, 04 September 2015

Cell Biology

Key words:Fibrosis, collagen, myofibroblasts, fibronectin, lysyl hydroxylase

Organism: Human

Cell Line: HDFa and HLFa Fibroblasts

587
Molecular profiling of long-term survivors identifies a subgroup of glioblastoma characterized by chromosome 19/20 co-gain

Christoph Geisenberger, Andreas Mock, Rolf Warta,Carmen Rapp, Christian Schwager, Andrey Korshunov, Ann-Katrin Nied, David Capper, Benedikt Brors, Christine Jungk, David Jones, V. Peter Collins, Koichi Ichimura, L. Magnus Bäcklund, Elena Schnabel, Michel

Acta Neuropathologica (Springer) Germany, UK, Japan, Sweden, USA, 01 September 2015

Pathology

Key words:Glioblastoma, molecular profiling, microglia, long-term survival, short-term survival

Organism: Human

Tissue: Brain

Pathological State: Cancer

588
Increased complexity in carcinomas: analyzing and modeling the interaction of human cancer cells with their microenvironment

Mira Stadler, Stefanie Walter, Angelika Walzl, Nina Kramer, Christine Unger, Martin Scherze, Daniela Unterleuthner, Markus Hengstschläger, Georg Krupitza, Helmut Dolznig

Seminars in Cancer Biology (Elsevier) Austria, 28 August 2015

Oncology

Key words:Carcinoma, human cancer cells, microenvironment

589
Vascular Proteomics Reveal Novel Proteins Involved in SMC Phenotypic Change: OLR1 as a SMC Receptor Regulating Proliferation and Inflammatory Response

Dong Hoon Kang, Mina Choi, Soyoung Chang, Min Young Lee, Doo Jae Lee, Kyungsun Choi, Junseong Park, Eun Chun Han, Daehee Hwang, Kihwan Kwon, Hanjoong Jo, Chulhee Choi, Sang Won Kang

PLOS ONE (PLOS) South Korea, 25 August 2015

Cell Biology

Key words:Carotid arteries, small interfering RNAs, transfection, proteomics, membrane proteins, immunohistochemistry techniques, protein interaction networks, network analysis

Organism: Human

Tissue: Blood Vessels

590
Acceleration of atherogenesis in ApoE−/− mice exposed to acute or low-dose-rate ionizing radiation

Mariateresa Mancuso, Emanuela Pasquali, Ignacia Braga-Tanaka, Satoshi Tanaka, Alessandro Pannicelli, Paola Giardullo, Simonetta Pazzaglia, Soile Tapio, Michael J. Atkinson, Anna Saran

Oncotarget (NCBI) Italy, Japan, Germany, 22 August 2015

Oncology

Key words:Atherosclerosis, ApoE mice, radiation, aorta

Organism: Mouse

Tissue: Heart, Blood Vessels

591
Stefin B deficiency reduces tumor growth via sensitization of tumor cells to oxidative stress in a breast cancer model

M Butinar, M T Prebanda, J Rajkovic, B Jeric, V Stoka, C Peters, T Reinheckel, A Krüger, V Turk, B Turk and O Vasiljeva

Oncogene (Nature) Slovenia, Germany, USA, 19 August 2015

Oncology

Key words:Tumor cells, oxidative stress, breast cancer

Organism: Mouse

Tissue: Breast

Pathological State: Cancer

592
Differential Utilization of Dietary Fatty Acids in Benign and Malignant Cells of the Prostate

Andrea Dueregger, Bernd Schöpf, Theresa Eder, Julia Höfer, Erich Gnaiger, Astrid Aufinger, Lukas Kenner, Bernhard Perktold, Reinhold Ramoner, Helmut Klocker, Iris E. Eder

PLOS ONE (PLOS) Austria, 18 August 2015

Oncology

Key words:Prostate gland, mitochondria, glucose, glucose metabolism, mitochondrial DNA, fatty acids, cell metabolism, prostate cancer

Organism: Human

Pathological State: Cancer

Cell Line: Prostate Cancer cells

593
Impact of CYP24A1 overexpression on growth of colorectal tumour xenografts in mice fed with vitamin D and soy

Julia Höbaus, Samawansha Tennakoon, Petra Heffeter, Charlotte Groesche, Abhishek Aggarwal, Doris M. Hummel, Ursula Thiem, Rodrig Marculescu, Walter Berger, Enikö Kállay

International Journal of Cancer (Wiley) Austria, 17 August 2015

Oncology

Key words:Colon cancer, vitamin D, CYP24A1, soy, xenograft

Organism: Human

Pathological State: Cancer

Cell Line: HT29 cells

594
Interleukin 2 Topical Cream for Treatment of Diabetic Foot Ulcer: Experiment Protocol

SWS Chan

JMIR Research Protocols (JMIR Publications) USA, 14 August 2015

Dermatology

Key words:type 1 diabetes, topical cream, chronic wound healing, immunotherapy, IL-2

Organism: Mouse

Tissue: Skin

595
An Echinococcus multilocularis antigen B3 proteoform that shows specific antibody responses against active stage alveolar echinococcosis

CS Ahn, H Cai, JG Kim, X Han, X Ma, YA Bae, HJ Yang, I Kang, H Wang, Y Kong

Journal of Clinical Microbiology (American Society for Microbiology) China, South Korea, 12 August 2015

Microbiology

Key words:Echinococcus multilocularis, Antigen B3, Antibody Response, Alveolar Echinococcosis

Organism: Human, Mouse

Tissue: Blood

Pathological State: Bacterial Infection

596
Mesenchymal stem cell-based HSP70 promoter-driven VEGFA induction by resveratrol alleviates elastase-induced emphysema in a mouse model

Young-Bin Chen, Ying-Wei Lan, Lih-Geeng Chen, Tsung-Teng Huang, Kong-Bung Choo, Winston T. K. Cheng, Hsuan-Shu Lee , Kowit-Yu Chong

Cell Stress and Chaperones (Springer) China, 05 August 2015

Cell Biology

Key words:Stem cell-based gene therapy, resveratrol Hsp70 promoter VEGFA, mouse model, emphysema

Organism: Mouse

Tissue: Lung

597
Abstract 1292: Validation study on quantitative analysis method of interrelationships between immune cells and prostate epithelial and cancer cells

Gero Kramer, Lukas Kenner, Thomas Szekeres, Shahrokh Shariat, Sarah Schwarz

Cancer Research (AACR) Austria, 01 August 2015

Oncology

Key words:Quantitative analysis, immune cells, prostate epithelial, cancer cells

Organism: Human

Tissue: Prostate

Pathological State: Cancer

598
Abstract 1091: A new image processing approach for functional context-based analysis of tryptase positive mast cells in cutaneous T-cell lymphomas

Radu Rogojanu, Johanna Eder, Waltraud Jerey, Gabriele Klosner, Verene Paulitschke, Isabella Ellinger, Theresia Thalhammer, Dan Kolmer, Franz Trautinger

Cancer Research (AACR) Austria, 01 August 2015

Oncology

Key words:Image processing, tryptase positive mast cells, cutaneous, T-cell lymphoma

Organism: Human

Tissue: Skin

Pathological State: Cancer

599
Significant Therapeutic Efficacy with Combined Radioimmunotherapy and Cetuximab in Preclinical Models of Colorectal Cancer

Vessela Vassileva, Vineeth Rajkumar, Mario Mazzantini, Mathew Robson, Adam Badar, Surinder Sharma, Erik Årstad, Daniel Hochhauser, Mark F. Lythgoe, Geoffrey M. Boxer, Rosmund Barbara Pedley

The Journal of Nuclear Medicine (SNMMI) UK, 01 August 2015

Oncology

Key words:Radioimmunotherapy, cetuximab, colorectal cancer

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

600
Early inflammatory responses following cell grafting in the CNS trigger activation of the subventricular zone: a proposed model of sequential cellular events

Praet J, Santermans E, Daans J, Le Blon D, Hoornaert C, Goossens H, Hens N, Van der Linden A, Berneman Z, Ponsaerts P.

Cell Transplantation (SAGE Journals) Belgium, 01 August 2015

Neuroscience

Key words:Cell transplantation, Graft apoptosis, Immune response, Angiogenesis, Cell proliferation

Organism: Mouse

Tissue: Brain

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