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Customer Publications (A total of 1320 papers published)

201
Endothelial colony forming cells from human umbilical cord blood improved severe erectile dysfunction in obese type II diabetic rats

Abrar Al-Mahmood Siddiqueea , P. Ganesan Adaikana, , Lang Chu Laua , Baharudin Bin Saida , Mark Chongb , Jerry Chanc , Swee Hin Teoh

Life Science (Elsevier) Singapore, 18 June 2018

Reproductive Medicine

Key words:Severe erectile dysfunction, Human endothelial colony forming cells, Intracavernosal pressure, Zucker diabetic fatty rats

Organism: Rat

Tissue: Penis

Pathological State: Erectile dysfunction

202
Substance P modulates bone remodeling properties of murine osteoblasts and osteoclasts

Tanja Niedermair, Stephan Schirner, Raphael Seebröker, Rainer H. Straub, Susanne Grässel

Scientific Reports (Nature) Germany, 15 June 2018

Physiology

Key words:Substance P, bone remodeling, osteoblasts, osteoclasts, Bone, Mechanisms of disease

Organism: Mouse

Cell Line: Osteoclast, Osteoblast

203
Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles

Sander C Steenbeek, Thang V Pham, Joep de Ligt, Anoek Zomer, Jaco C Knol, Sander R Piersma, Tim Schelfhorst, Rick Huisjes, Raymond M Schiffelers, Edwin Cuppen, Connie R Jimenez, Jacco van Rheenen

The EMBO Journal (EMBO press) The Netherlands, 15 June 2018

Oncology

Key words:Cre‐LoxP; extracellular vesicles; intratumoral heterogeneity; intravital microscopy; signaling networks

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

204
Quantitative measurement of breast carcinoma fibrosis for the prediction in the risk of bone metastasis

Chong Sun, Bin Wang, Jianmin Li, Junjie Shangguan, Matteo Figini, Kang Zhou, Liang Pan, Quanhong Ma, Zhuoli Zhang

American Journal of Translational Research (e-Century Publishing Corporation) China, 15 June 2018

Oncology

Key words:Invasive breast carcinoma; bone metastasis; collagen deposition; early prediction

Organism: Human

Tissue: Breast

Pathological State: Cancer

205
Synergistic Antitumor Effect of Oligogalacturonides and Cisplatin on Human Lung Cancer A549 Cells

Cian-Song Huang, Ai-Chun Huang, Ping-Hsiu Huang, Diana Lo, Yuh-Tai Wang, Ming-Chang Wu

International Journal of Molecular Sciences (MDPI) Taiwan, 14 June 2018

Oncology

Key words:adjuvant therapy; cisplatin; oligogalacturonides; synergistic effect

Organism: Human

Pathological State: Cancer

Cell Line: A549 (Lung carcinoma cells)

206
Nerve Growth Factor (NGF)—Receptor Survival Axis in Head and Neck Squamous Cell Carcinoma

József Dudás, Wolfgang Dietl, Angela Romani, Susanne Reinold, Rudolf Glueckert, Anneliese Schrott-Fischer, Daniel Dejaco, Lejo Johnson Chacko, Raphaela Tuertscher, Volker Hans Schartinger, Herbert Riechelmann

International Journal of Molecular Sciences (MDPI) Austria, 14 June 2018

Oncology

Key words:TissueFaxs; cell cycle arrest; cytokeratin; necrosis

Organism: Human

Tissue: Oral Mucosa

Pathological State: Cancer

207
Breast Cancer Histological Image Classification Using Fine-Tuned Deep Network Fusion

A Mahbod, I Ellinger, R Ecker, Ö Smedby, C Wang

(Springer) , 06 June 2018

Key words:Breast cancer Histological images Classification Deep learning

208
Targeted intracerebral delivery of the anti-inflammatory cytokine IL13 promotes alternative activation of both microglia and macrophages after stroke

Somayyeh Hamzei Taj, Debbie Le Blon, Chloé Hoornaert, Jasmijn Daans, Alessandra Quarta, Jelle Praet, Annemie Van der Linden, Peter Ponsaerts, Mathias Hoehn

Journal of Neuroinflammation (Springer) Germany, 04 June 2018

Immunology

Key words:Interleukin 13; Mesenchymal stem cells; Microglia/macrophage polarization; Neuroinflammation; Stroke

Organism: Mouse

Tissue: Brain

Pathological State: Cerebral Ischemia

209
Novel Conducting and Biodegradable Copolymers with Noncytotoxic Properties toward Embryonic Stem Cells

Aruã C. da Silva, Ana Teresa S. Semeano, André H. B. Dourado, Henning Ulrich, Susana I. Cordoba de Torresi

ACS OMEGA (ACS Publications) Brazil, 31 May 2018

Stem Cell Research

Key words:Cell and Molecular biology; Conducting polymers; Environmental biology; Polyesters

Organism: Human

Cell Line: Human embryonic stem cells (hESCs)

210
Hierarchical Multiplexing Nanodroplets for Imaging-Guided Cancer Radiotherapy via DNA Damage Enhancement and Concomitant DNA Repair Prevention

Wei Jiang, Quan Li, Liang Xiao, Jiaxiang Dou, Yi Liu, Wenhao Yu, Yinchu Ma, Xiaoqiu Li, Ye-Zi You, Zhuting Tong, Hang Liu, Hui Liang, Ligong Lu, Xiaoding Xu, Yandan Yao, Guoqing Zhang, Yucai Wang, and Jun Wang

ACS NANO (ACS Publications) China, 29 May 2018

Nanomedicine

Key words:cancer radiotherapy; DNA damage and repair; hierarchical nanostructure; multimodal imaging; tumor hypoxia

Organism: Mouse

Tissue: Allograft Tumor

Pathological State: Cancer

211
Identification of galectin-3 as an autoantigen in patients with IgG4-related disease

Cory A. Perugino, DO,a,b* Sultan B. AlSalem, MBBS, MMSc,b,c* Hamid Mattoo, PhD,b Emanuel Della-Torre, MD, PhD,b,d Vinay Mahajan, Gayathri Ganesh, Hugues Allard-Chamard, Zachary Wallace, Sydney B. Montesi, Johannes Kreuzer, Wilhelm Haas, John H. Stone, Shiv Pillai

Journal of Allergy and Clinical Immunology (Elsevier) UK, USA, Italy, 29 May 2018

Immunology

Key words:IgG4-related disease, plasmablast, autoantigen, galectin-3, autoantibody

Organism: Human

Tissue: Pancreas

Pathological State: IgG4-Related Disease

212
Acellular vascular matrix grafts from human placenta chorion: Impact of ECM preservation on graft characteristics, protein composition and in vivo performance

Karl H. Schneider, Marjan Enayati, Christian Grasl, Ingrid Walter, Lubos Budinsky, Gabriel Zebic, Christoph Kaun, Anja Wagner, Klaus Kratochwill, Heinz Redl, Andreas Teuschl, Bruno K. Podesser, Helga Bergmeister

Biomaterials (Elsevier) Austria, 29 May 2018

Tissue Engineering

Key words:Decellularized matrix, Human placenta, Small diameter vascular grafts, Cell migration, Biocompatibility

Organism: Human

Tissue: Placenta

213
Allocation of Interferon Gamma mRNA Positive Cells in Caecum Hallmarks a Protective Trait Against Histomonosis

Fana Alem Kidane, Taniya Mitra, Patricia Wernsdorf, Michael Hess, Dieter Liebhart

Frontiers in Immunology (Frontiers Media S.A.) Austria, 28 May 2018

Immunology

Key words:Histomonas meleagridis; histomonosis; image analysis; immunofluorescence; in situ hybridization; interferon gamma; interleukin-13; vaccination

Organism: Turkey, Chicken

Tissue: Small Intestine, Liver, Spleen

Pathological State: Parasitic Infection

214
The overexpression of Fra1 disorders the inflammatory cytokine secretion by mTEC of myasthenia gravis thymus

Q.‐R. Li W.‐P. Ni N.‐J. Lei J.‐Y. Yang X.‐Y. Xuan P.‐P. Liu G.‐M. Gong F. Yan Y.‐S. Feng R. Zhao Y. Du

Scandinavian journal of Immunology (Blackwell Publishing Inc.) China, 28 May 2018

Neuroscience

Key words:Fos-related antigen-1; inflammatory cytokine; medulla thymic epithelial cells; myasthenia gravis

Organism: Human

Tissue: Thymus

Pathological State: Myasthenia Gravis

215
Therapeutic effects of dietary intervention on neuroinflammation and brain metabolism in a rat model of photothrombotic stroke

Ewelina Kurtys Cindy Casteels Caroline C. Real Ulrich L. M. Eisel J. Martin Verkuyl Laus M. Broersen Hans C. Klein Rudi A. J. O. Dierckx Janine Doorduin Erik F. J. de Vries

CNS Neuroscience and Therapeutics (Wiley) The Netherlands, 27 May 2018

Neuroscience

Key words:PET imaging; neuroinflammation; nutrition; photothrombotic stroke

Organism: Rat

Tissue: Brain

Pathological State: Cerebral Ischemia

216
Decreased argininosuccinate synthetase expression in Thai patients with cholangiocarcinoma and the effects of ADI-PEG20 treatment in CCA cell lines

Somphon Roeksomtawin, Panida Navasumrit, Somchamai Waraprasit, Varabhorn Parnlob, Thaniya Sricharunrat, Vajarabhongsa Bhudhisawasdi, Niramol Savaraj, Mathuros Ruchirawat

Oncology Letters (Spandidos Publications) Thailand, 24 May 2018

Oncology

Key words:Ki-67; arginine deprivation; argininosuccinate synthetase; cholangiocarcinoma; pegylated arginine deiminase

Organism: Human

Tissue: Liver

Pathological State: Cancer

Cell Line: Cholangiocarcinoma cell lines (RmCCA-1 and HuCCA), human fibroblast cell line (BJ-1)

217
Cordycepin induces apoptosis of human ovarian cancer cells by inhibiting CCL5-mediated Akt/NF-κB signaling pathway

Zhen Yang Cui, Soo Jung Park, Eunbi Jo, In-Hu Hwang, Kyung-Bok Lee, Sung-Woo Kim, Dae Joon Kim, Jong Chun Joo, Seok Hoon Hong, Min-Goo Lee and Ik-Soon Jang

Cell Death Discovery (Nature) South Korea, USA, 23 May 2018

Oncology

Organism: Human

Pathological State: Cancer

Cell Line: SKOV-3 cells

218
BMP-2 restoration aids in recovery from liver fibrosis by attenuating TGF-β1 signaling

Yueh-Hua Chung, Ying-Hsien Huang, Tien-Huei Chu, Chun-Lin Chen, Pey-Ru Lin, Shih-Chung Huang, Deng-Chyang Wu, Chao-Cheng Huang, Tsung-Hui Hu, Ying-Hsien Kao and Ming-Hong Tai

Laboratory Investigation (Nature) Taiwan, 22 May 2018

Hepathology

Key words:BMP-2, liver fibrosis, TGF-β1 signaling

Organism: Human

Tissue: Liver

Pathological State: Hepatitis, Liver Cirrhosis

219
Kinin and Purine Signaling Contributes to Neuroblastoma Metastasis

Henning Ulrich, Mariusz Z. Ratajczak, Gabriela Schneider, Elena Adinolfi, Elisa Orioli, Enéas G. Ferrazoli, Talita Glaser, Juliana Corrêa-Velloso, Poliana C. M. Martins, Fernanda Coutinho, Ana P. J. Santos, Micheli M. Pillat, Ulrich Sack, Claudiana Lameu

Frontiers in Pharmacology (Frontiers Media S.A.) Brazil, 18 May 2018

Oncology

Key words:bone marrow; bradykinin; metastasis; neuroblastoma; purinergic system

Organism: Human

Pathological State: Cancer

Cell Line: CHP-100 cells

220
Lactobacillus casei Variety rhamnosus Probiotic Preventively Attenuates 5-Fluorouracil/Oxaliplatin-Induced Intestinal Injury in a Syngeneic Colorectal Cancer Model

Ching-Wei Chang, Chia-Yuan Liu, Hung-Chang Lee, Yen-Hua Huang, Li-Hui Li, Jen-Shiu Chiang Chiau, Tsang-En Wang, Cheng-Hsin Chu, Shou-Chuan Shih, Tung-Hu Tsai, Yu-Jen Chen

Frontiers in Microbiology (Frontiers Media S.A.) Taiwan, 15 May 2018

Oncology

Key words:FOLFOX; Lactobacillus; apoptosis; gut microbiota; intestinal mucositis

Organism: Mouse

Tissue: Allograft Tumor

Pathological State: Cancer

221
A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment

Amelie Griveau, GiorgioS eano, Samuel J. Shelton, Robert Kupp, Arman Jahangiri, Kirsten Obernier, Shanmugarajan Krishnan, Olle R. Lindberg, Tracy J. Yuen, An-Chi Tien, Jennifer K.Sabo, Nancy Wang, Ivy Chen, Jona sKloepper, Louis Larrouquere, Mitrajit Ghosh, Itay Tirosh, Emmanuelle Huillard, Arturo Alvarez-Buylla, Michael C. Oldham, Anders I. Persson, William A. Weiss, Tracy T. Batchelor, Anat Stemmer-Rachamimov, Mario L.Suvà, Joanna J. Phillips, Manish K .Aghi, Shwetal Mehta, Rakesh K. Jain, David H. Rowitch

Cancer Cell (Cell Press) USA, 14 May 2018

Oncology

Key words:Olig2; Wnt; angiogenesis; astrocyte; blood-brain barrier; glioma; invasiveness; oligodendrocyte precursor; p53; vessel co-option

Organism: Human, Mouse

Tissue: Brain, Xenograft Tumor

Pathological State: Cancer

222
Catalpol inhibits migration and induces apoptosis in gastric cancer cells and in athymic nude mice

Zheng-HuaWangZhan-ShengHu

Biomedicine and Pharmacotherapy (Elsevier) China, 14 May 2018

Oncology

Key words:Gastric cancer, Catalpol, Migration, Apoptosis and ROS, DDP

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

223
DNA damage predicts prognosis and treatment response in colorectal liver metastases superior to immunogenic cell death and T cells

Johannes Laengle, Judith Stift, Agnes Bilecz, Brigitte Wolf, Andrea Beer, Balazs Hegedus, Stefan Stremitzer, Patrick Starlinger, Dietmar Tamandl, Dietmar Pils, Michael Bergmann

Theranostics (Ivyspring International Publisher) Austria, 10 May 2018

Oncology

Key words:DNA damage, calreticulin, immunogenic cell death, colorectal liver metastases

Organism: Human

Tissue: Colon

Pathological State: Cancer

224
Hematological findings in non-treated and gamma-irradiated mice deficient for MIC-1/GDF15.

M. HOFER, Z. HOFEROVÁ, J. REMŠÍK, M. NOVÁKOVÁ, J. PROCHÁZKOVÁ, R. FEDR, J. KOHOUTEK, L. DUŠEK, A. HAMPL, K. SOUČEK

Physiological Research (BioMed Central) Czech Republic, 10 May 2018

Hematology

Key words:GDF15 knockout mice; hematopoiesis; ionizing radiation; stress-induced cytokine

Organism: Mouse

Tissue: Spleen, Bone

225
Regorafenib inhibits tumor progression through suppression of ERK/NF-κB activation in hepatocellular carcinoma bearing mice

Mao-Chi Weng, Mei-Hui Wang, Jai-Jen Tsai, Yu-Cheng Kuo, Yu-Chang Liu, Fei-Ting Hsu, Hsin-Ell Wang

Bioscience Reports (Kluwer Academic Publishers) Taiwan, 05 May 2018

Oncology

Key words:Bioluminescence imaging; Regorafenib; apoptosis; hepatocellular carcinoma; nuclear factor kappaB

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

226
Effects of chitosan and chitosan N-acetylcysteine solutions on conjunctival epithelial cells

N Schuerer, E Stein, A Inic-Kanada, E Ghasemian, Marijana Stojanovic, Jacqueline Montanaro, Nora Bintner, Christine Hohenadl, Robert Sachsenhofer, Talin Barisani-Asenbauera

Journal of EuCornea (Elsevier) Austria, Serbia, 02 May 2018

Ophthalmology

Key words:Chitosan Chitosan-N-acetylcysteine Uptake Conjunctival epithelial cells Drug delivery

Organism: Guinea Pig

Tissue: Eye

227
Rab37 in lung cancer mediates exocytosis of soluble ST2 and thus skews macrophages toward tumor‐suppressing phenotype

Hong‐Tai Tzeng Ching‐Chin Su Chih‐Peng Chang Wu‐Wei Lai Wu‐Chou Su Yi‐Ching Wang

International journal of cancer (Wiley) Taiwan, 01 May 2018

Oncology

Key words:Rab37; ST2; exocytosis; macrophage; tumor microenvironment

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

228
Eupatilin inhibits the proliferation of human esophageal cancer TE1 cells by targeting the Akt‑GSK3β and MAPK/ERK signaling cascades

Xiaona Wang Yanyan Zhu Lili Zhu Xinhuan Chen Yanyan Xu Yafei Zhao Yingzhe Shao Feng Li Yanan Jiang Jing Lu Youtian Huang Xiaobin Chang Juan Zhang Xiang Li Kangdong Liu Mingyao Zhao Ziming Dong Jimin Zhao

Oncology Reports (Demetrios A. Spandidos Ed. and Pub.) China, 23 April 2018

Oncology

Key words:Eupatilin, human esophageal cancer, TE1 cells, Akt‑GSK3β, MAPK/ERK

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

229
Blimp-1 prolongs allograft survival without regimen via influencing T cell development in favor of regulatory T cells while suppressing Th1

Aline Yen LingWanga Charles Yuen YungLoh Shyi-JouChen Huang-KaiKao Cheng-HungLin Sheng-HaoChuang Chin-MingLee Huey-KangSytwu Fu-ChanWei

Molecular Immunology (Elsevier) Taiwan, 23 April 2018

Immunology

Key words:Allograft tolerance, B lymphocyte-induced maturation protein, T cells

Organism: Mouse

Tissue: Skin

Pathological State: Organ Transplantation

230
IL-33/ST2 axis mediates hyperplasia of intrarenal urothelium in obstructive renal injury

Wei-Yu Chen, Jenq-Lin Yang, Yi-Hsiu Wu, Lung-Chih Li, Ru-Fang Li, Ya-Ting Chang, Lo-Hsin Dai, Wan-Chen Wang, Ya-Jen Chang

Experimental and Molecular Medicine (Nature) Taiwan, 20 April 2018

Nephrology

Key words:IL-33/ST2 axis, hyperplasia, renal injury, unilateral ureteral obstruction (UUO)

Organism: Mouse

Tissue: Kidney

Pathological State: Kidney Injury

231
Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal

Samra Turajlic, Hang Xu, Kevin Litchfield, Andrew Rowan, Stuart Horswell, Tim Chambers

CELL (Cell Press) UK, 19 April 2018

Oncology

Key words:branched evolution; cancer evolution; chromosome instability; deterministic evolution; intratumor heterogeneity; linear evolution; metastasis; punctuated evolution; renal cell cancer; tumor diversity

Organism: Human

Tissue: Kidney

Pathological State: Cancer

232
Tumor-induced generation of splenic erythroblast-like Ter-cells promotes tumor progression

Han Y, Liu Q, Hou J, Gu Y, Zhang Y, Chen Z, Fan J, Zhou W, Qiu S, Zhang Y, Dong T, Li N, Jiang Z, Zhu H, Zhang Q, Ma Y, Zhang Q, Wang Q, Yu Y, Li N, Cao X

CELL (Cell Press) China, 19 April 2018

Oncology

Key words:Ter-119; Ter-cell; artemin; cancer immunotherapy; erythroblast-like; hepatocellular carcinoma; prognosis biomarker

Organism: Mouse

Tissue: Liver

Pathological State: Cancer

233
Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal

Samra Turajlic, Hang Xu, Kevin Litchfield, Andrew Rowan, Tim Chambers, Jose I. Lopez, David Nicol

CELL (Cell Press) UK, 19 April 2018

Oncology

Key words:chromosome instability; cytoreductive nephrectomy; evolution of metastasis; loss of 9p; metastasectomy; metastasis; oligometastasis; renal cell cancer; solitary metastasis

Organism: Human

Tissue: Kidney

Pathological State: Cancer

234
Conditional depletion of GSK3b protects oligodendrocytes from apoptosis and lessens demyelination in the acute cuprizone model

Bin Xing Lauren E. Brink Kelly Maers Mara L. Sullivan Richard J. Bodnar Donna B. Stolz Franca Cambi

GLIA (Wiley) USA, 18 April 2018

Neuroscience

Key words:GSK3b; cell death; glia; multiple sclerosis

Organism: Mouse

Tissue: Brain

235
CD10 inhibits cell motility but expression is associated with advanced stage disease in colorectal cancer

Teresa P.RaposoabMireia SuecaComescAdeyemiIdowuaBoraAgitaJamesHassallabWakkasFadhilabRobertNicadRupertEckerdTakashiYaoeMohammadIlyas

Experimental and Molecular Pathology (Elsevier) UK, 11 April 2018

Oncology

Key words:CD10, NEP, CALLA, Colorectal cancer, Epithelial-mesenchymal transition, Metastasis

Organism: Human

Tissue: Colon

Pathological State: Cancer

236
Increased HOXA5 expression provides a selective advantage for gain of whole chromosome 7 in IDH wild-type glioblastoma

Patrick J. Cimino Youngmi Kim Hua-Jun Wu Jes Alexander, Hans-Georg Wirsching Frank Szulzewsky,1 Ken Pitter,7 Tatsuya Ozawa,1,8 Jiguang Wang,9,10,16 Julio Vazquez,11 Sonali Arora,1 Raul Rabadan Ross Levine Franziska Michor and Eric C. Holland

Genes and Development (Cold Spring Harbor Laboratory Press) USA, 09 April 2018

Oncology

Key words:glioblastoma, HoxA, homeobox RCAS, chromosome 7 gain

Organism: Mouse

Tissue: Brain

Pathological State: Cancer

237
Photodynamic Effect of Methylene Blue and Low Level Laser Radiation in Head and Neck Squamous Cell Carcinoma Cell Lines

Barbara Kofler, Angela Romani, Christian Pritz, Teresa Bernadette Steinbichler, Volker Hans Schartinger, Herbert Riechelmann, Jozsef Dudas

International Journal of Molecular Sciences (MDPI) Austria, 07 April 2018

Oncology

Key words:TissueFaxs; head and neck carcinoma; methylene blue; photodynamic therapy

Organism: Human

Pathological State: Cancer

Cell Line: Detroit 562 cells (pharynx carcinoma)

238
The expansion in lymphoid organs of IL-4+ BATF+ T follicular helper cells is linked to IgG4 class switching in vivo

Takashi Maehara, Hamid Mattoo, Vinay S Mahajan, Samuel JH Murphy, Grace J Yuen, Noriko Ishiguro, Miho Ohta, Masafumi Moriyama, Takako Saeki, Hidetaka Yamamoto, Masaki Yamauchi, Joe Daccache, Tamotsu Kiyoshima, Seiji Nakamura, John H Stone, Shiv Pillai

Life Science Alliance () USA, Japan, 05 April 2018

Immunology

Key words:T follicular helper (TFH), BATF+ ,IgG4 class switching, Sjögren’s syndrome,secondary lymphoid organs

Organism: Human

Tissue: Salivary Gland

239
Glycyrrhetinic Acid Antagonizes Pressure-Induced Venous Remodeling in Mice

Hanna Kuk,Caroline Arnold,Andreas H. Wagner,Markus Hecker,Carsten Sticht, and Thomas Korff

Frontiers in Physiology (Frontiers Media S.A.) Germany, 04 April 2018

Physiology

Key words:endothelial cells; spider veins; venous hypertension; venous remodeling; wall stress

Organism: Human

Cell Line: HUVEC, HUVSMC (human umbilical vein endothelial and SMCs)

240
Amentoflavone enhances the therapeutic efficacy of sorafenib by inhibiting anti-apoptotic potential and potentiating apoptosis in hepatocellular carcinoma in vivo

JJ Tsai, FT Hsu, PJ Pan, CW Chen, YC Kuo

Anticancer Research (International Institute of Anticancer Research) Taiwan, 01 April 2018

Oncology

Key words:Amentoflavone sorafenib hepatocellular carcinoma ERK AKT apoptosis

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

241
Cordyceps militaris Extract Inhibits the NF-κB pathway and Induces Apoptosis through MKK7-JNK Signaling Activation in TK-10 Human Renal Cell Carcinoma

SJ Park, HJ Jang, IH Hwang, JM Kim, E Jo, MG Lee, IS Jang, J Cheon Joo

Natural Product Communications (SAGE Journals) South Korea, 01 April 2018

Oncology

Key words:Cordyceps militaris, Apoptosis, NF-κB, MKK7, JNK, TK-10

Organism: Human

Pathological State: Cancer

Cell Line: TK-10 renal cancer cell lines

242
Periostin antisense oligonucleotide suppresses bleomycin‐induced formation of a lung premetastatic niche for melanoma

Takashi Semba Eiji Sugihara Nagisa Kamoshita Sayaka Ueno Keitaro Fukuda Masafumi Yoshino Kazumasa Takao Kazunori Yoshikawa Kenji Izuhara Yoshimi Arima Makoto Suzuki Hideyuki Saya

Cancer Science (Wiley) Japan, 31 March 2018

Oncology

Key words:antisense oligonucleotide; lung fibrosis; melanoma; periostin; premetastatic niche

Organism: Mouse

Tissue: Lung

243
MRI‐guided interventional natural killer cell delivery for liver tumor treatment

Zhanliang Su, Xifu Wang, Linfeng Zheng, Tianchu Lyu, Matteo Figini, Bin Wang, Daniel Procissi, Junjie Shangguan, Chong Sun, Liang Pan, Lei Qin, Bin Zhang, Yury Velichko, Riad Salem, Vahid Yaghmai, Andrew C. Larson, Zhuoli Zhang

Cancer Medicine (Wiley) USA, 30 March 2018

Oncology

Key words:Adoptive transfer immunotherapy; hepatocellular carcinoma; interventional oncology; magnetic resonance imaging; natural killer cell

Organism: Rat

Tissue: Liver

Pathological State: Cancer

244
Collagen morphology influences macrophage shape and marker expression in vitro

Gwenda F. Vasse, Philipp T. Kühn, Qihui Zhou, Shardul A. Bhusari, Catharina Reker-Smit, Barbro N. Melgert, Patrick van Rijn

Journal of Immunology and Regenerative Medicine (Elsevier) The Netherlands, 30 March 2018

Immunology

Key words:Extracellular matrix, Collagen type I, Pulmonary fibrosis, Ym1, CD206, Migration

Organism: Human

Cell Line: Alveolar-like Makrophhages

245
Olaparib is effective in combination with, and as maintenance therapy after, first‐line endocrine therapy in prostate cancer cells

Gertrud E. Feiersinger1,Kristina Trattnig1, Peter D. Leitner, Fabian Guggenberger,Alexander Oberhuber, Sarah Peer, Martin Hermann, Ira Skvortsova, Jana Vrbkova, Jan Bouchal, Zoran Culig and Fred eric R. Santer

Molecular Oncology (Wiley) Austria, 15 March 2018

Oncology

Key words:PARP inhibition; combination therapy; endocrine therapy; maintenance therapy; olaparib; prostate cancer

Organism: Human

Pathological State: Cancer

Cell Line: LNCaP-abl (Prostate carcinoma cell lines)

246
Loss of Neuroglobin Expression Alters Cdkn1a/Cdk6-Expression Resulting in Increased Proliferation of Neural Stem Cells

Evi Luyckx, Wendy Van Leuven, Daniel Andre, Alessandra Quarta, Kristien Reekmans, Erik Fransen, Luc Moens, Thomas Hankeln, Peter Ponsaerts, and Sylvia Dewilde

Stem Cells and Development (Mary Ann Liebert Inc.) Belgium, Germany, 15 March 2018

Stem Cell Research

Key words:neuroglobin – cell cycle – transcriptomics – neural stem cells

Organism: Mouse

Cell Line: Neural stem cells

247
Effects of iota-carrageenan on ocular Chlamydia trachomatis infection in vitro and in vivo

Aleksandra Inic-Kanada, Elisabeth Stein, Marijana Stojanovic, Nadine Schuerer, Ehsan Ghasemian, Ana Filipovic, Emilija Marinkovic, Dejana Kosanovic, Talin Barisani-Asenbauer

Journal of Applied Phycology (Kluwer Academic Publishers) Austria, 13 March 2018

Microbiology

Key words:Carrageenan, Trachoma, Natural products, Chlamydia

Organism: Human

Pathological State: Bacterial Infection

Cell Line: HCjE cells (human corneal-limbal and conjunctival epithelial cell line)

248
Prostaglandin E2 Is Required for BMP4-Induced Mesoderm Differentiation of Human Embryonic Stem Cells

Bowen Zhang,1,2,3 Lijuan He,1,2,3 Yiming Liu,1,2 Jing Zhang,1,2 Quan Zeng,1,2 Sihan Wang,1,2 Zeng Fan,1,2 Fang Fang Lin Chen Yang Lv Jiafei Xi Wen Yue Yanhua Li and Xuetao Pei

Stem Cell Reports (Cell Press) China, 13 March 2018

Stem Cell Research

Key words:prostaglandin E2, cyclooxygenase-1, BMP4, mesoderm, differentiation, human embryonic stem cells, β-catenin,

Organism: Human

Cell Line: WA01 and WA09 hESCs

249
Atlas of the Striatum and Globus Pallidus in the Tree Shrew: Comparison with Rat and Mouse

Rong-Jun Ni,Zhao-Huan Huang,Yu-Mian Shu,Yu Wang Tao Li, Jiang-Ning Zhou

Neuroscience Bulletin (Springer) China, 05 March 2018

Neuroscience

Key words:Striatum, Globus pallidus, Basal ganglia, Reconstruction, Rodent, Parvalbumin

Organism: Treeshrew, Rat, Mouse

Tissue: Brain

250
Novel platforms of multiplexed immunofluorescence for study of paraffin tumor tissues

Edwin Roger Parra

Journal of Cancer Treatment and Diagnosis () USA, 01 March 2018

Cytometry

Key words:Multiplexed proteins identification Immunofluorescence Signal Amplification Spatial Cell Distribution Image Analysis

251
4:20 PM Abstract No. 350 Interferon-gamma-eluting microspheres for MRI-guided immunotherapy of liver cancer

W.ParkA.GordonS.ChoX.HuangK.HarrisZ.ZhangA.LarsonD.Kim

Journal of Vascular and Interventional Radiology (Elsevier) USA, 01 March 2018

Oncology

Organism: Rabbit

Tissue: Liver

Pathological State: Cancer

252
In vitro behavior of human mesenchymal stem cells on poly(N-isopropylacrylamide) based biointerfaces obtained by matrix assisted pulsed laser evaporation

Madalina Icriverzi, Laurentiu Rusen, Livia Elena Sima, Antoniu Moldovan, Simona Brajnicov, Anca Bonciu, Natalia Mihailescu, Maria Dinescu, Anisoara Cimpean, Anca Roseanu, Valentina Dinca

Applied Surface Science (Elsevier) Romania, 28 February 2018

Cell Biology

Key words:pNIPAM coatings, MAPLE, mesenchymal stem cells

Organism: Human

Cell Line: Human mesenchymal stem cells (hMSCs)

253
[18F]FEPPA: Improved Automated Radiosynthesis, Binding Affinity, and Preliminary in Vitro Evaluation in Colorectal Cancer

Neydher Berroterán-Infante, Theresa Balber, Petra Fürlinger, Michael Bergmann, Rupert Lanzenberger, Marcus Hacker, Markus Mitterhauser and Wolfgang Wadsak

Medicinal Chemistry Letters (ACS Publications) Austria, 21 February 2018

Radiotherapy

Key words:Affinity, autoradiography, colorectal cancer, FEPPA, radiosynthesis, TSPO

Organism: Human

Tissue: Colon

Pathological State: Cancer

254
CXCL5 facilitates melanoma cell-neutrophil interaction and lymph node metastasis

Ana Soler Cardona, Agnes Forsthuber, Katharina Lipp, Stefanie Ebersbergr, Magdalena Heinz, Klaudia Schossleitner, Elisabeth Buchberger, Mario Gröger, Peter Petzelbauer, Christoph Hoeller, Erwin Wagner, Robert Loewe

Journal of Investigative Dermatology (Elsevier) Austria, 21 February 2018

Dermatology

Key words:CXCL5, melanoma cells, chemokine mRNA expression

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

255
Hypoxia-Preconditioned Human Umbilical Vein Endothelial Cells Protect Against Neurovascular Damage After Hypoxic Ischemia in Neonatal Brain

Yi-Chao Lee, Ying-Chao Chang, Chia-Ching Wu,Chao-Ching Huang

Molecular Neurobiology (Springer) Taiwan, 19 February 2018

Neuroscience

Key words:Neonatal brain injury, neurovascular protection, hypoxia-preconditioned, human umbilical vein endothelial cells, hypoxia-inducible factor 1-alpha

Organism: Human

Cell Line: HUVECs (Human umbilical vein endothelial cells)

256
Inflammatory Monocytes Drive Influenza A Virus–Mediated Lung Injury in Juvenile Mice

Bria M. Coates, Kelly L. Staricha, Clarissa M. Koch, Yuan Cheng, Dale K. Shumaker, G. R. Scott Budinger, Harris Perlman, Alexander V. Misharin and Karen M. Ridge

The Journal of Immunology (American Association of Immunologists) USA, 14 February 2018

Immunology

Key words:Influenza A virus (IAV), NLRP3 inflammasome, cytokines, monocytes

Organism: Mouse

Tissue: Lung, Heart

257
Preclinical In Vitro and In Vivo Evaluation of [18F]FE@SUPPY for Cancer PET Imaging: Limitations of a Xenograft Model for Colorectal Cancer

T. Balber, J.Singer, N. Berroterán-Infante, M. Dumanic, L. Fetty, J. Fazekas-Singer , C. Vraka, L. Nics, M. Bergmann, K. Pallitsch, H. Spreitzer, W. Wadsak , M. Hacker, E. Jensen-Jarolim, H. Viernstein, and M. Mitterhauser ,

Contrast Media and Molecular Imaging (Wiley) Austria, 13 February 2018

Oncology

Key words:[18F]FE@SUPPY, Cancer PET Imaging, Colorectal Cancer

Organism: Mouse

Tissue: Colon

Pathological State: Cancer

258
Calcium signaling mediates five types of cell morphological changes to form neural rosettes

Hana Hříbková, Marta Grabiec, Dobromila Klemová, Iva Slaninová, Yuh-Man Sun

Journal of Cell Science (The Company of Biologists) Czech Republic, 12 February 2018

Neuroscience

Key words:Embryonic stem cells, neural stem cell niche, neural rosette formation, calcium, neurogenesis, adherens junctions, cytoskeleton proteins

Organism: Human

Cell Line: Human ESC-derived neural rosettes

259
Functional loss of p53 cooperates with the in vivo microenvironment to promote malignant progression of gastric cancers

Junko Ohtsuka, Hiroko Oshima, Issei Ezawa, Ryo Abe, Masanobu Oshima and Rieko Ohki

Scientific Reports (Nature) Japan, 02 February 2018

Oncology

Key words:Gastric cancer, p53 mutations, tumour-suppressor proteins

Organism: Mouse

Tissue: Stomach

Pathological State: Cancer

260
Differentiation-associated urothelial cytochrome P450 oxidoreductase predicates the xenobiotic-metabolizing activity of “luminal” muscle-invasive bladder cancers

Simon C. Baker, Volker M. Arlt, Radek Indra, Madeleine Joel, Marie Stiborová, Ian Eardley, Niaz Ahmad, Wolfgang Otto, Maximilian Burger, Peter Rubenwolf, David H. Phillips, Jennifer Southgate

Molecular Carcinogenesis (Wiley) UK, 01 February 2018

Oncology

Key words:Urothelium, carcinogens, normal human urothelial (NHU) cells , EROD activity

Organism: Human

Cell Line: NHU cells (Normal human urothelial)

261
Angiogenin Attenuates Scar Formation in Burn Patients by Reducing Fibroblast Proliferation and Transforming Growth Factor β1 Secretion

SC Pan, CH Lee, CL Chen, WY Fang, LW Wu

Annals of Plastic Surgery (LWW Journals) Taiwan, 01 February 2018

Regenerative Medicine

Key words:angiogenin, fibroblast, scar, Smad2, transforming growth factor β1

Organism: Human

Tissue: Skin

Pathological State: Burn Wound

262
Grey matter OPCs are less mature and less sensitive to IFNγ than white matter OPCs: consequences for remyelination

Dennis H. Lentferink, Jacomien M. Jongsma, Inge Werkman and Wia Baron

Scientific Reports (Nature) The Netherlands, 01 February 2018

Neuroscience

Key words:Multiple sclerosis (MS), central nervous system, oligodendrocyte progenitor cells (OPCs)

Organism: Rat

Cell Line: OPS cells (Oligodendrocyte progenitor cells)

263
Assessing the selective therapeutic efficacy of superparamagnetic erlotinib nanoparticles in lung cancer by using quantitative magnetic resonance imaging and a nuclear factor kappa-B reporter gene system

Fei-Ting Hsu, Hua-Shan Liu, Ahmed Atef Ahmed Ali, Ping-Huei Tsai, Yu-Chieh Kao, Chia-Feng Lu, Hsu-Shan Huang Cheng-Yu Chen

Nanomedicine: Nanotechnology, Biology and Medicine (Elsevier) Taiwan, 31 January 2018

Nanomedicine

Key words:Erlotinib, superparamagnetic iron oxide, magnetic resonance imaging, nuclear factor-κBNon-small-cell lung cancer

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

264
Expression of cystatin C in the female reproductive tract and its effect on human sperm capacitation

Robert Kuo-Kuang Lee, Huan-Chin Tseng, Yuh-Ming Hwu, Chi-Chen Fan, Ming-Huei Lin, Jhih-Jie Yu, Ling-Yu Yeh and Sheng-Hsiang Li

Reproductive Biology and Endocrinology (Springer) Taiwan, 30 January 2018

Reproductive Medicine

Key words:Cystatin C (CST3), seminal plasma, sperm protein tyrosine phosphorylation

Organism: Human

Tissue: Uterus

265
AXL promotes Zika virus infection in astrocytes by antagonizing type I interferon signalling

Jian Chen, Yi-feng Yang, Yu Yang, Peng Zou, Jun Chen, Yongquan He, Sai-lan Shui, Yan-ru Cui, Ru Bai, Ya-jun Liang, Yunwen Hu, Biao Jiang, Lu Lu, Xiaoyan Zhang, Jia Liu and Jianqing Xu

Nature Microbiology (Nature) China, 29 January 2018

Microbiology

Key words:Zika virus (ZIKV), neonatal microcephaly, Guillain–Barré syndrome, AXL

Organism: Mosquito

Pathological State: Virus Infection

Cell Line: C6/36 cells

266
SPK1-transfected UCMSC has better therapeutic activity than UCMSC in the treatment of experimental autoimmune encephalomyelitis model of Multiple sclerosis

Yun-Liang Wang, Peng Xue, Chun-Yang Xu, Zhen Wang, Xin-Shan Liu, Lin-Lin Hua, Hong-Ying Bai, Zhi-Lei Zeng, Hai-Feng Duan and Jin-Feng Li

Scientific Reports (Nature) China, 29 January 2018

Neuroscience

Key words:Multiple Sclerosis (MS), central nervous system , permanent neurological damage, cytokine

Organism: Human

Cell Line: Human umbilical cord mesenchymal stem cells (HUC-MSC-SPK1)

267
Histamine drives severity of innate inflammation via histamine 4 receptor in murine experimental colitis

J B Wechsler, A Szabo, C L Hsu, R A Krier-Burris, H A Schroeder, M Y Wang, R G Carter, T E Velez, L M Aguiniga, J B Brown, M L Miller, B K Wershil, T A Barrett and P J Bryce

Mucosal Immunology (Nature) USA, 24 January 2018

Immunology

Organism: Mouse

Tissue: Colon

Pathological State: Colitis

268
Injectable hydroxyphenyl derivative of hyaluronic acid hydrogel modified with RGD as scaffold for spinal cord injury repair

Kristyna Zaviskova, Dmitry Tukmachev, Jana Dubisova, Irena Vackova, Ales Hejcl, Julie Bystronova, Martin Pravda, Ivana Scigalkova, Romana Sulakova, Vladimir Velebny, Lucie Wolfova, Sarka Kubinova

Journal of Biomedical Materials Research (Wiley) Czech Republic, 23 January 2018

Tissue Engineering

Key words:Hydrogel, spinal cord injury (SCI), hydroxyphenyl derivative of hyaluronic acid (HA-PH)

Organism: Rat

Tissue: Spinal Cord

Pathological State: Spinal Cord Injury

269
CCR5/CCL5 axis interaction promotes migratory and invasiveness of pancreatic cancer cells

Santosh Kumar Singh, Manoj K. Mishra, Isam-Eldin A. Eltoum, Sejong Bae, James W. Lillard Jr. and Rajesh Singh

Scientific Reports (Nature) USA, 22 January 2018

Oncology

Key words:Pancreatic cancer (PC), CCR5, CCL5, F-actin polymerization

Organism: Human

Tissue: Pancreas

Pathological State: Cancer

270
Posterior reversible encephalopathy syndrome in stroke-prone spontaneously hypertensive rats on high-salt diet

Fanny Herisson, Iris Zhou, Jerome Mawet, E Du, Arnavaz H Barfejani, Tao Qin, Marilyn J Cipolla, Philip Z Sun, Natalia S Rost, Cenk Ayata

Journal of Cerebral Blood Flow and Metabolism (SAGE Journals) USA, 19 January 2018

Oncology

Key words:Animal models, hypertension, posterior cerebral reversible encephalopathy, cerebral blood flow, white matter

Organism: Rat

Tissue: Brain

Pathological State: Encephalopathy

271
Simvastatin induces G1 arrest by up-regulating GSK3β and down-regulating CDK4/cyclin D1 and CDK2/cyclin E1 in human primary colorectal cancer cells

Ming-Jenn Chen, An-Ching Cheng, Ming-Fen Lee, Yi-Chiang Hsu

Journal of Cellular Physiology (Wiley) Taiwan, 15 January 2018

Oncology

Key words:Simvastatin (SIM), colorectal cancer (CRC), CDK4/cyclin D1

Organism: Human

Tissue: Colon

Pathological State: Cancer

272
Canine macrophages can like human macrophages be in vitro activated toward the M2a subtype relevant in allergy

Ina Herrmanna, Jelena Gotovina, Judit Fazekas-Singera, Michael B.Fischer, Karin Hufnagl, Rodolfo Bianchini, Erika Jensen-Jarolima

Developmental and Comparative Immunology (Elsevier) Austria, 10 January 2018

Immunology

Key words:Allergy , canine, comparative, DH82M1 macrophage, M2a macrophage, polarization

Organism: Dog, Human

Pathological State: Cancer

Cell Line: U937 and DH82 cells (Makrophage like cells)

273
Formation of nanotubular TiO2 structures with varied surface characteristics for biomaterial applications

Robinson Aguirre, Mónica Echeverry-Rendón, David Quintero, Juan G. Castaño, Martin C. Harmsen, Sara Robledo, Félix Echeverría E

Journal of Biomedical Materials Research (Wiley) Colombia, 09 January 2018

Biological Materials

Key words:Anodization, titanium, nanotubular TiO2, counterion

Organism: Human

Cell Line: Adipose tissue derived stromal cells (ADSC)

274
Physical-chemical characterization and biological assessment of simple and lithium-doped biological-derived hydroxyapatite thin films for a new generation of metallic …

A.C.Popescu, P.E.Florian, G.E.Stan, G.Popescu-Pelin, I.Zgura, M.Enculescu, F.N.Oktard, R.Trusca, L.E.Sima, A.Roseanu, L.Duta

Applied Surface Science (Elsevier) Romania, Turkey, 06 January 2018

Tissue Engineering

Key words:Biological-derived hydroxyapatite, Lithium doping, Pulsed Laser Deposition, Sustainable resources, In vitro assessment

Organism: Human

Cell Line: Human mesenchymal stem cells (hMSCs)

275
Does combined therapy of curcumin and epigallocatechin gallate have a synergistic neuroprotective effect against spinal cord injury?

Jiri Ruzicka, Lucia Machova Urdzikova, Barbora Svobodova, Anubhav G. Amin, Kristyna Karova, Jana Dubisova, Kristyna Zaviskova, Sarka Kubinova, Meic Schmidt, Meena Jhanwar-Uniyal, and Pavla Jendelova

Neural Regeneration Research (Publishing House of Neural Regeneration Research) Czech Republic, USA, 01 January 2018

Regenerative Medicine

Key words:spinal cord injury, epigallocatechin gallate, curcumin, inflammatory response, neural regeneration

Organism: Rat

Tissue: Spinal Cord

Pathological State: Spinal Cord Injury

276
Zinc finger protein 143 expression is closely related to tumor malignancy via regulating cell motility in breast cancer

AR Paek, JY Mun, KM Hong, J Lee, DW Hong, HJ You

BMb Reports (NCBI) South Korea, 31 December 2017

Oncology

Key words:Invasive ductal carcinoma, Metastasis, Motility, ZNF143

Organism: Human

Tissue: Breast

Pathological State: Cancer

277
AKT3 drives adenoid cystic carcinoma development in salivary glands

Katalin Zboray, Julian Mohrherr, Patricia Stiedl, Klemens Pranz, Laura Wandruszka, Beatrice Grabner, Robert Eferl, Richard Moriggl, Dagmar Stoiber, Kazuhito Sakamoto, Kay-Uwe Wagner, Helmut Popper, Emilio Casanova, Herwig P. Moll

Cancer Medicine (Wiley) Austria, 28 December 2017

Oncology

Key words:AKT3, adenoid cystic carcinoma, MMTV-tTA mouse model, oncogene addiction, salivary gland cancer

Organism: Mouse

Tissue: Salivary Gland

Pathological State: Cancer

278
A benchmark for comparing precision medicine methods in thyroid cancer diagnosis using tissue microarrays

Ching-Wei Wang, Yu-Ching Lee, Evelyne Calista, Fan Zhou, Hongtu Zhu, Ryohei Suzuki, Daisuke Komura, Shumpei Ishikawa, Shih-Ping Cheng

Bioinformatics (Oxford University Press) Taiwan, USA, Japan, 23 December 2017

Biological Methods

Key words:precision medicine, cancer diagnosis, tissue microarray

Organism: Human

Tissue: Thyroid

Pathological State: Cancer

279
Recurrent infection progressively disables host protection against intestinal inflammation

WH Yang, DM Heithoff, PV Aziz, M Sperandio, V Nizet, MJ Mahan, JD Marth

Science (American Association for the Advancement of Science) USA, Germany, 22 December 2017

Immunology

Key words:Recurrent infection, host protection, intestinal inflammation

Organism: Mouse

Tissue: Small Intestine, Colon

Pathological State: Inflammation

280
Actein induces autophagy and apoptosis in human bladder cancer by potentiating ROS/JNK and inhibiting AKT pathways

Lu Ji, Bing Zhong, Xi Jiang, Fei Mao, Gang Liu, Bin Song, Cheng-Yuan Wang, Yong Jiao, Jiang-Ping Wang, Zhi-Bin Xu, Xing Li, and Bo Zhan

Oncotarget (Impact Journals) China, 22 December 2017

Oncology

Key words:human bladder cancer, Actein (ACT), autophagy and apoptosis, ROS and JNK, AKT

Organism: Mouse, Human

Tissue: Xenograft Tumor, Liver, Lung, Kidney

Pathological State: Cancer

281
CD151, A Novel Host Factor of Nuclear Export Signaling in Influenza Virus Infection

Yongkang Qiao, Yan Ya, Kai Sen Tan, Sheryl SL. Tan, Ju Ee Seet, Thiruma Valavan Arumugam, Vincent TK. Chow, De Yun Wang

Journal of Allergy and Clinical Immunology (Elsevier) Singapore, 21 December 2017

Immunology

Key words:Influenza A virus (IAV), CD151, nuclear export, host innate immunity, inflammasome, IAV severity

Organism: Mouse

Tissue: Lung

Pathological State: Virus Infection

282
Renal allograft rejection, lymphocyte infiltration, and de novo donor-specific antibodies in a novel model of non-adherence to immunosuppressive therapy

Louisa Kühne, Bettina Jung, Helen Poth, Antonia Schuster, Simone Wurm, Petra Ruemmele, Bernhard Banas, Tobias Bergler

BMC Immunology (BioMed Central) Germany, 19 December 2017

Immunology

Key words:Donor specific antibodies, humoral rejection, renal transplantation, non-adherence, leukocyte infiltration, BAFF

Organism: Rat

Tissue: Kidney

Pathological State: Organ Transplantation

283
Magnolol inhibits venous remodeling in mice

Hanna Kuk, Caroline Arnold, Ralph Meyer, Markus Hecker and Thomas Korff

Scientific Reports (Nature) Germany, 19 December 2017

Cardiology

Key words:Magnolol, venous vasculature, endothelial cells, varicose/spider veins, peripheral vascular disease

Organism: Human

Cell Line: HUVECs (Human umbilical vein endothelial cells)

284
Mitochondrial ROS activates ERK/autophagy pathway as a protected mechanism against deoxypodophyllotoxin-induced apoptosis

Sang-Hun Kim, Kwang-Youn Kim, Sul-Gi Park, Sun-Nyoung Yu, Young-Wook Kim, Hyo-Won Nam, Hyun-Hee An, Young-Woo Kim, and Soon-Cheol Ahn

Oncotarget (Impact Journals) South Korea, USA, 19 December 2017

Oncology

Key words:Deoxypodophyllotoxin, apoptosis, autophagy, mitochondrial ROS, ERK

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

285
Research report TDP-43 proteolysis is associated with astrocyte reactivity after traumatic brain injury in rodents Abbreviated title: TDP-43 proteolysis is …

CY Huang, YC Lee, PC Li, PC Liliang, K Lu, KW Wang, LC Chang, LY Shiu, MF Chen, YT Sun, HK Wang

Journal of Neuroimmunology (Elsevier) Taiwan, 15 December 2017

Neuroscience

Key words:Astrocyte, Astrogliosis, Traumatic brain injury, Transactivation response DNA-binding protein 43

Organism: Rat

Tissue: Brain

Pathological State: Traumatic Brain Injury

286
Novel Hydrogel-Advanced Modified Clay Nanocomposites as Possible Vehicles for Drug Delivery and Controlled Release

Raluca Ianchis, Claudia M. Ninciuleanu, Ioana C. Gifu, Elvira Alexandrescu, Raluca Somoghi, Augusta R. Gabor, Silviu Preda, Cristina L. Nistor, Sabina Nitu, Cristian Petcu, Madalina Icriverzi, Paula E. Florian and Anca M. Roseanu

Nanomaterials (MDPI) Romania, 13 December 2017

Nanomedicine

Key words:hydrogel; clay; nanocomposites; biocompatibility

Organism: Cow

Cell Line: HT29 and MDBK cells

287
18F-FDG PET Biomarkers Help Detect Early Metabolic Response to Irreversible Electroporation and Predict Therapeutic Outcomes in a Rat …

Xifu Wang, Zhanliang Su, Tianchu Lyu, Matteo Figini, Daniel Procissi, Junjie Shangguan, Chong Sun, Bin Wang, Na Shang, Shanzhi Gu, Quanhong Ma, Andrew C. Gordon, Kai Lin, Jian Wang, Robert J. Lewandowski, Riad Salem, Vahid Yaghmai, Andrew C. Larson, Zhuoli Zhang

Radiology (Radiological Society of North America) USA, China, 12 December 2017

Radiotherapy, Oncology

Key words:18F-FDG PET, Biomarkers, Metabolic Response, Irreversible Electroporation, Liver Tumor

Organism: Rat

Tissue: Liver

Pathological State: Cancer

288
Comparison of MOLLI, shMOLLLI, and SASHA in discrimination between health and disease and relationship with histologically derived collagen volume fraction

Nicholas Child, Gonca Suna, Darius Dabir, May-Lin Yap, Toby Rogers, Misha Kathirgamanathan, Eduardo Arroyo-Ucar, Rocio Hinojar, Islam Mahmoud, Christopher Young, Olaf Wendler, Manuel Mayr, Banher Sandhu, Geraint Morton, Marion Muhly-Reinholz, Stefanie Dimmeler, Eike Nagel, Valentina O Puntmann

European Heart Journal (Oxford University Press) UK, Germany, Spain, 11 December 2017

Cardiology

Key words:T1 mapping, MOLLI, shMOLLI, SASHA, collagen, aortic valve stenosis, myocardium, troponin, myocardial fibrosis, collagen, respiratory care units, therapeutic equivalency, transverse spin relaxation time

Organism: Human

Tissue: Heart

Pathological State: Fibrosis

289
INO80 haploinsufficiency inhibits colon cancer tumorigenesis via replication stress-induced apoptosis

Shin-Ai Lee, Han-Sae Lee, Shin-Kyoung Hur, Sang Won Kang, Goo Taeg Oh, Daekee Lee, and Jongbum Kwon

Oncotarget (Impact Journals) South Korea, 06 December 2017

Oncology

Key words:INO80 chromatin remodeling complex, colon cancer, APC Min mouse model, replication stress, apoptosis

Organism: Mouse

Tissue: Small Intestine, Colon

Pathological State: Cancer

290
Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer

An Ning Cheng, Chi-Chen Fan, Yu-Kang Lo, Cheng-Liang Kuo, Hui-Chun Wang, I.-Hsin Lien, Shu-Yu Lin, Chung-Hsing Chen, Shih Sheng Jiang, I.-Shou Chang, Hsueh-Fen Juan, Ping-Chiang Lyu and Alan Yueh-Luen Lee

Scientific Reports (Nature) Taiwan, 05 December 2017

Oncology

Key words:Phosphorylation, cancer therapeutic resistance, Cdc7-Dbf4 kinase, stress

Organism: Human

Tissue: Oral Mucosa

Pathological State: Cancer

291
Nocturnal resveratrol administration inhibits chemically induced breast cancer formation in rats

T. KISKOVA, V. DEMECKOVA, Z. JENDZELOVSKA, M. KIKTAVA, K. VENGLOVSKA, M. BOHMDORFER, W. JAGER, T. THALHAMMER

JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (Polish Physiological Society) Slovakia, Austria, 01 December 2017

Oncology

Key words:resveratrol, circadian rhythm, carcinogenesis, breast cancer, immunity, reactive oxygen species

Organism: Rat

Tissue: Breast

Pathological State: Cancer

292
IgE autoreactivity in bullous pemphigoid: eosinophils and mast cells as major targets of pathogenic immune reactants

P.C. Freire, C.H. Muñoz, G. Stingl

British Journal of Dermatology (Wiley) Austria, 28 November 2017

Dermatology

Key words:Bullous pemphigoid (BP), urticarial eruptions, IgG, IgE

Organism: Human

Tissue: Skin

Pathological State: Bullous Pemphigoid

293
Interaction of factor VII activating protease (FSAP) with neutrophil extracellular traps (NETs)

Simona Grasso, Ariane Neumann, Irene M.Lang, Michael Etscheid, Marenvon Köckritz-Blickwede, Sandip M.Kanse

Thrombosis Research (Elsevier) Austria, Germany, Norway, 21 November 2017

Cell Biology

Key words:NETs, FSAP, thrombosis, inflammation

Organism: Human

Tissue: Blood Vessels

294
Analysis of anti-TNF-induced skin lesions reveals strong Th1 activation with some distinct immunological characteristics

E. Stoffel, H. Maier, E. Riedl, M.-C. Brüggen, B. Reininger, M. Schaschinger, C. Bangert, E. Guenova, G. Stingl, P.M. Brunner

British Journal of Dermatology (Wiley) Austria, USA, 16 November 2017

Dermatology

Key words:Psoriasiform, eczematous eruptions, anti-TNF-α therapy, IFN-γ

Organism: Human

Tissue: Skin

Pathological State: Crohn's Disease, Colitis, Rheumatoid Arthritis, Psoriasis, Eczema

295
Chronic Stress Alters Striosome-Circuit Dynamics, Leading to Aberrant Decision-Making

Alexander Friedman, Daigo Homma, Bernard Bloem, Leif G.Gibb, Ken-ichi Amemori, Dan Hu, Sebastien Delcasso, Timothy F.Truong, Joyce Yang, Adam S.Hood, Katrina A.Mikofalvy, Dirk W.Beck, Norah Nguyen, Erik D.Nelson, Sebastian E.Toro Arana, Ruth H.Vorder Bruegge, Ki A.Goosens, Ann M.Graybiel

CELL (Cell Press) USA, 16 November 2017

Neuroscience

Key words:Striatum, basal ganglia, cost-benefit, prefrontal cortex, optogenetics, prelimbic cortex, parvalbumin-positive interneurons, fast-spiking interneuron, sexcitation-inhibition balance

Organism: Rat

Tissue: Brain

296
Controlled release of liposome-encapsulated temozolomide for brain tumour treatment by convection-enhanced delivery

Chung-Yin Lin, Rui-Jin Li, Chiung-Yin Huang, Kuo-Chen Wei

Journal of Drug Targeting (Taylor and Francis) Taiwan, 14 November 2017

Oncology

Key words:Convention-enhanced delivery, drug delivery, liposome, temozolomide, brain tumour

Organism: Mouse

Tissue: Brain

Pathological State: Cancer

297
Phospholipase D inhibitors reduce human prostate cancer cell proliferation and colony formation

Amanda R Noble, Norman J Maitland, Daniel M Berney and Martin G Rumsby

British Journal of Cancer (Nature) UK, 14 November 2017

Oncology

Key words:Phospholipases, mTOR, PKB/Akt, prostate cancer (PCa), benign prostatic hyperplasia (BPH)

Organism: Human

Tissue: Kidney, Prostate

Pathological State: Cancer

298
Analysis of the Human Mucosal Response to Cholera Reveals Sustained Activation of Innate Immune Signaling Pathways

Daniel L. Bourque, Taufiqur Rahman Bhuiyan, Diane P. Genereux, Rasheduzzaman Rashu, Crystal N. Ellis, Fahima Chowdhury, Ashraful I. Khan, Nur Haq Alam, Anik Paul Lazina Hossain, Leslie M. Mayo-Smith, Richelle C. Charles, Ana A. Weil, Regina C. LaRocque, Stephen B. Calderwood, Edward T. Ryan, Elinor K. Karlsson, Firdausi Qadri and Jason B. Harris

Infection and Immunity (American Society for Microbiology) USA, 13 November 2017

Immunology

Key words:Vibrio cholerae infection, cholera, Caco-2 or THP-1 cells

Organism: Human

Tissue: Small Intestine

Pathological State: Bacterial Infection

299
Digital image analysis in breast pathology—from image processing techniques to artificial intelligence

Stephanie Robertson, Hossein Azizpour, Kevin Smith, Johan Hartman

Translational Research (Elsevier) Sweden, 07 November 2017

Oncology

Key words:Breast cancer, histopathology, biomarker, artificial intelligence (AI)

Organism: Human

Tissue: Breast

Pathological State: Cancer

300
Cyclin D1 promoter -56 and -54 bp CpG un-methylation predicts invasive progression in arsenic-induced Bowen’s disease

Wei-Ting Liao, Huey-Ling You, Chee-Yin Chai, Chih-Hung Lee, Cheng-Che E. Lang, Shun-Jen Chang, Chu-Ling Yui, Hsin-Su Yu

Journal of Dermatological Science (Elsevier) Taiwan, 31 October 2017

Oncology

Key words:Arsenic-induced Bowen’s disease, cyclin D1 un-methylation, aneuploidy, predictor, invasive progression

Organism: Human

Tissue: Skin

Pathological State: Bowen’s Disease, Cancer

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