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Customer Publications (A total of 1320 papers published)

101
The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease

Lindsay Kosack, Bettina Wingelhofer, Alexandra Popa, Bojan Vilagos, Anna Orlova, Peter Majek, Katja Parapatics, Alexander Lercher, Benedikt Agerer, Anna Ringler, Johanna Klughammer, Mark Smyth, Kseniya Khamina, Hatoon Baazim, David A. Rosa, Jisung Park, Patrick T. Gunning, Christoph Bock, Hannah V. Siddle, Stefan Kubicek, Elizabeth P. Murchison, Keiryn L. Bennett, Richard Moriggl, View ORCID ProfileAndreas Bergthaler

Cancer Cell (Cell Press) Austria, Canada, UK, Australia, 14 January 2019

Oncology

Key words:ERBB, horizontal transmission, MHC class I, receptor tyrosine kinases, STAT3, Tasmanian devil, transmissible cancer, tumor vulnerability, systems biology xenograft

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

102
An integrated characterization of contractile, electrophysiological, and structural cardiotoxicity of Sophora tonkinensis Gapnep. in human pluripotent stem cell …

Ruiying Wang, Min Wang, Shan Wang, Ke Yang, Ping Zhou, Xueheng Xie, Qi Cheng, Jingxue Ye, Guibo Sun and Xiaobo Sun

Stem Cell Research and Therapy (Springer) China, 11 January 2019

Stem Cell Research

Key words:Cardiotoxicity, Sophora tonkinensis, hiPSC-CMs, Cardio-NLCS

Organism: Human

Cell Line: Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)

103
Brain-Derived Neurotrophin and TrkB in Head and Neck Squamous Cell Carcinoma

Dudás J, Riml A, Tuertscher R, Pritz C, Steinbichler TB, Schartinger VH, Sprung S, Glueckert R, Schrott-Fischer A, Johnson Chacko L, Riechelmann H

International Journal of Molecular Sciences (MDPI) Austria, 11 January 2019

Oncology

Key words:epithelial–mesenchymal transition; vimentin; cytokeratin; p53 mutation; paraffin embedding; riboprobe

Organism: Human

Tissue: Head, Neck

Pathological State: Cancer

104
Clinical significance of c-Met and phospho-c-Met (Tyr1234/1235) in ovarian cancer

L Lim, CC Wu, YT Hsu, FJ Sun, CL Chang

Taiwanese Journal of Obstetrics and Gynecology (Elsevier) Taiwan, 09 January 2019

Oncology

Key words:c-Met, phospho-c-Met, Ovarian cancer

Organism: Human

Tissue: Breast

Pathological State: Cancer

105
High-Throughput Synapse-Resolving Two-Photon Fluorescence Microendoscopy for Deep-Brain Volumetric Imaging In Vivo

Guanghan Meng, Yajie Liang, Sarah Sarsfield, Wan-chen Jiang, Rongwen Lu, Joshua Tate Dudman, Yeka Aponte, Na Ji

eLife (eLife Sciences Publications) USA, 03 January 2019

Neuroscience

Key words:two-photon fluorescence microendoscopy, volumetric imaging, Bessel beam, hippocampus, lateral hypothalamus

Organism: Mouse

Tissue: Brain

106
Genetic labeling reveals temporal and spatial expression pattern of D2 dopamine receptor in rat forebrain

Qing Yu, Ying-Zi Liu, Yan-Bing Zhu, Yao-Yi Wang, Qian Li, Dong-Min Yin

Brain Structure and Function (Springer) China, 02 January 2019

Neuroscience

Key words:Drd2, Knockin rats, Olfactory bulb, Cerebral cortex, Hippocampus 

Organism: Mouse, Rat

Tissue: Brain

107
Abundance of the Organic Anion-transporting Polypeptide OATP4A1 in Early-Stage Colorectal Cancer Patients: Association With Disease Relapse

V Buxhofer-Ausch, M Sheikh, C Ausch, S Zotter, H Bauer, M Mollik, A Reiner, A Gleiss, W Jäger, C Sebesta, S Kriwanek, T Thalhammer

Applied … (Ingentaconnect) , 01 January 2019

108
Loss of the dystonia gene Thap1 leads to transcriptional deficits that converge on common pathogenic pathways in dystonic syndromes

Natalie M Frederick, Parth V Shah, Alessandro Didonna ,Monica R Langley, Anumantha G Kanthasamy, Puneet Opal

Human Molecular Genetics (Oxford University Press) USA, 26 December 2018

Neuroscience

Key words:alleles, phenotype, dopamine, signal transduction, transcription, genetic basal ganglia dystonia homeostasis cytoskeleton embryo genes gliosis mice, knockout movement disorders rna, messenger synaptic transmission up-regulation (physiology) zinc fingers cerebellum mice transcription factor agonists antagonists haploinsufficiency nervous system development nestin protein torsion dystonia 6 loss of function mutation

Organism: Mouse

Tissue: Brain

109
Effects of cylindrospermopsin on cultured immortalized human airway epithelial cells

Barbara Kubickova, Petra Laboha, Jan-Peter Hildebrandt, Klara Hilscherová, Pavel Babica

Chemosphere (Elsevier) Czech Republic, Germany, 22 December 2018

Toxicology

Key words:Cyanobacteria, Cyanotoxin, HBE, Inhalation toxicity, MAPK

Organism: Human

Cell Line: Human bronchial epithelial cell line (HBE) 16HBE14o-cells

111
Spatial mapping of myeloid cells and macrophages by multiplexed tissue staining

Joshua Saylor, Zhaoxuan Ma, Helen S. Goodridge, Fangjin Huang, Anne E. Cress, Stephen J. Pandol, Stephen L. Shiao, Adriana C. Vidal, Lily Wu, Nicholas G. Nickols, Arkadiusz Gertych and Beatrice S. Knudsen

Frontiers in Immunology (Frontiers Media S.A.) USA, 14 December 2018

Immunology

Key words:FFPE; immunofluorescence; immunohistochemistry; macrophage; multiplex; myeloid; spatial profiling

Organism: Human

Tissue: Colon, Tonsil

Pathological State: Cancer

112
Predominant Striatal Input to the Lateral Habenula in Macaques Comes from Striosomes

Simon Hong, Satoko Amemori, Emily Chung, Daniel J. Gibson, Ken-ich iAmemori , Ann M.Graybiel

Current Biology (Cell Press) USA, Japan, 13 December 2018

Neuroscience

Key words:basal ganglia, dopamine, motivation, non-human primate, mood, learning, microstimulation

Organism: Monkey

Tissue: Brain

113
Melanocyte-specific gene 1 promotes melanoma progression by enhancing the expression of Bcl-2

Hui Zhao, Guosheng Wu, Ji Zhu, Mengyan Sun, Yuchong Wang, Yongjie Fan, Kai Wu, Hongda Bi, Haiying Dai, Chuan Lv, Chunyu Xue

Oncology Letters (Spandidos Publications) China, 12 December 2018

Oncology

Key words:melanocyte-specific gene 1, melanoma, cell viability, apoptosis, Bcl-2

Organism: Human

Tissue: Skin

Pathological State: Cancer

114
The FAK inhibitor BI 853520 inhibits spheroid formation and orthotopic tumor growth in malignant pleural mesothelioma

Viktoria Laszlo, Zsuzsanna Valko, Judit Ozsvar, Ildiko Kovacs, Tamas Garay, Mir Alireza Hoda, Thomas Klikovits, Paul Stockhammer, Clemens Aigner, Marion Gröger, Walter Klepetko, Walter Berger, Michael Grusch, Jozsef Tovari, Irene C. Waizenegger, Balazs Dome, Balazs Hegedus

Journal of Molecular Medicine (Springer) Austria, Germany, Hungary, 11 December 2018

Oncology

Key words:Mesothelioma, Focal adhesion kinase, Tyrosine kinase inhibitor, Angiogenesis, Spheroid formation, Orthotopic xenograft

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

115
Anti-inflammatory compound curcumin and mesenchymal stem cells in the treatment of spinal cord injury in rats.

Jiri Ruzicka, Lucia Machova Urdzikova, Anna Kloudova, Anubhav G. Amin, Jana Vallova, Sarka Kubinova, Meic H. Schmidt, Meena Jhanwar‑Uniyal and Pavla Jendelova

Acta Neurobiologiae Experimentalis (Nencki Institute of Experimental Biology) Czech Republic, USA, 05 December 2018

Regenerative Medicine

Key words:Spinal cord injury, human mesenchymal stem cells, curcumin, combined therapy, inflammatory response

Organism: Rat

Tissue: Spinal Cord

Pathological State: Spinal Cord Injury

Cell Line: Human mesenchymal stem cells (hMSCs)

116
The natural polyphenol curcumin induces apoptosis by suppressing STAT3 signaling in esophageal squamous cell carcinoma

Ying Liu, Xinhua Wang, Shuang Zeng, Xiane Zhang, Jimin Zhao, Xiaoyan Zhang, Xinhuan Chen, Wanjing Yang, Yili Yang, Ziming Dong, Jingyu Zhu Xin Xu, Fang Tian

Journal of Experimental and Clinical Cancer Research (Springer) China, 05 December 2018

Oncology

Key words:Curcumin, STAT3, Esophageal squamous cell carcinoma, Apoptosis, PDX model

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

117
Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression

Bing Song, Su-Hong Park, Jonathan C. Zhao, Ka-wing Fong, Shangze Li, Yongik Lee, Yeqing A. Yang, Subhasree Sridhar, Xiaodong Lu, Sarki A. Abdulkadir, Robert L. Vessella, Colm Morrissey, Timothy M. Kuzel, William J. Catalona, Ximing J. Yang, and Jindan Yu

Journal of Clinical Investigation (American Society for Clinical Investigation) USA, China, 04 December 2018

Oncology

Key words:Genetics; Oncology; Prostate cancer

Organism: Human

Tissue: Prostate

Pathological State: Cancer

118
Extracellular vesicles from mature dendritic cells (DC) differentiate monocytes into immature DC

Stefan Schierer, Christian Ostalecki, Elisabeth Zinser, Ricarda Lamprecht, Bianca Plosnita, Lena Stich, Jan Dörrie, ProfileManfred B Lutz, ProfileGerold Schuler, ProfileAndreas S Baur

Life Science Alliance () Germany, Austria, 03 December 2018

Immunology

Key words:Medical Research, Immunology

Organism: Human, Mouse

Cell Line: Monocyte-derived dentritic cells

119
Elevated Serum Interleukin-8 Level Correlates with Cancer-Related Cachexia and Sarcopenia: An Indicator for Pancreatic Cancer Outcomes

Ya-Chin Hou , Chih-Jung Wang , Ying-Jui Chao , Hao-Yun Chen , Hao-Chen Wang, Hui-Ling Tung , Jung-Ting Lin and Yan-Shen Shan

Journal of Clinical Medicine (MDPI) Taiwan, 01 December 2018

Oncology

Key words:pancreatic cancer; cancer cachexia; sarcopenia; interleukin (IL)-1β; IL-6; IL-8; tumor necrosis factor (TNF)-α

Organism: Human

Tissue: Pancreas

Pathological State: Cancer

120
Freshwater cyanotoxin cylindrospermopsin has detrimental stage-specific effects on hepatic differentiation from human embryonic stem cells

Tereza Vanova, Jan Raska, Pavel Babica, Iva Sovadinova, Michaela Kunova Bosakova, Petr Dvorak Ludek Blaha, Vladimir Rotrekl

Toxicological Sciences (Oxford University Press) Czech Republic, 30 November 2018

Stem Cell Research

Key words:cylindrospermopsin, hepatic differentiation, human embryonic stem cells, liver, cyanotoxin

Organism: Human

Cell Line: Human embryonic stem cell (hESCs)

121
Pterostilbene Attenuates Hexavalent Chromium-Induced Allergic Contact Dermatitis by Preventing Cell Apoptosis and Inhibiting IL-1β-Related NLRP3 Inflammasome Activation

Bour-Jr Wang , Hui-Wen Chiu, Yong-Lin Lee, Chia-Yi Li, Ying-Jan Wang, and Yu-Hsuan Lee

Journal of Clinical Medicine (MDPI) Taiwan, 27 November 2018

Allergy

Key words:Hexavalent chromium; pterostilbene; endoplasmic reticulum stress; inflammatory cytokines; NLRP3 inflammasome; allergic contact dermatitis

Organism: Mouse

Tissue: Skin

Pathological State: Dermatitis

122
ONECUT2 Is a Targetable Master Regulator of Lethal Prostate Cancer That Suppresses the Androgen Axis

Mirja Rotinen, Sungyong You, Julie Yang, Simon G. Coetzee, Mariana Reis-Sobreiro, Wen-Chin Huang, Fangjin Huang, Xinlei Pan, Alberto Yáñez, Dennis J. Hazelett, Chia-Yi Chu, Kenneth Steadman, Colm M. Morrissey, Peter S. Nelson, Eva Corey, Leland W. K. Chung, Stephen J. Freedland, Dolores Di Vizio, Isla P. Garraway, Ramachandran Murali, Beatrice S. Knudsen & Michael R. Freeman

Nature Medicine (Nature) USA, Taiwan, 26 November 2018

Oncology

123
Immune Cell and Cell Cluster Phenotyping, Quantitation, and Visualization Using In Silico Multiplexed Images and Tissue Cytometry

Kim R.M. Blenman, Marcus W. Bosenberg

Cytometry Part A (Wiley) USA, 23 November 2018

Cytometry

Key words:immune cells, cell clusters, quantitative imaging, multiplexed histology, tissue cytometry, TissueFAXS in silico analysis, FFPE

Organism: Mouse

Tissue: Spleen

Pathological State: Cancer

124
PD-L1 expression and the prognostic significance in gastric cancer: a retrospective comparison of three PD-L1 antibody clones (SP142, 28–8 and E1L3N)

Jing Ma, Jianhui Li, Meirui Qian, Weili Han, Miaomiao Tian, Zengshan Li, Zhe Wang, Shuixiang He and Kaichun Wu

Diagnostic Pathology (Springer) China, 21 November 2018

Oncology

Key words:Programmed cell death ligand 1, Immunohistochemistry, H-score, Multiplexed immunofluorescence

Organism: Human

Tissue: Stomach

Pathological State: Cancer

125
MicroRNA-451a overexpression induces accelerated neuronal differentiation of Ntera2/D1 cells and ablation affects neurogenesis in microRNA-451a-/- mice

Christa Trattnig , Muammer Üçal , Carmen Tam-Amersdorfer, Angela Bucko, Ulrike Zefferer, Gerda Grünbacher, Markus Absenger-Novak, Kristin Anna Öhlinger, Klaus Kraitsy, Daniel Hamberger, Ute Schaefer , Silke Patz

PLOS ONE (PLOS) Austria, 21 November 2018

Neuroscience

Key words:Neuronal differentiation, Neurites, Cell differentiation, Neurospheres, MicroRNAs , Neural networks, Fluorescence microscopy, Nestin

Organism: Mouse

Tissue: Brain

126
Oxidative muscles have better mitochondrial homeostasis than glycolytic muscles throughout life and maintain mitochondrial function during aging

Annunziata N. Crupi , Jordan S. Nunnelee , David J. Taylor , Amandine Thomas , Jean-Philippe Vit , Celine E. Riera 5 , Roberta A. Gottlieb , Helen S. Goodridge

Aging (Impact Journals) USA, 18 November 2018

Physiology

Key words:Aging; glycolytic; mitochondria; oxidative; sarcopenia; skeletal muscle

Organism: Mouse

Tissue: Muscle

127
Effect of dentin matrix components on the mineralization of human mesenchymal stromal cells

Dr. Xenos Petridis, Mr. Bas Pieter Beems, Dr. Phillip Tomson, Dr. Ben Scheven, Dr. Ben Giepmans, Dr. Jeroen Kuipers, Dr. Luc van der Sluis, Dr. Martin C Harmsen

Tissue Engineering Part A (Mary Ann Liebert Inc.) The Netherlands, UK, 16 November 2018

Tissue Engineering

Key words:dental pulp, dentin matrix, mesenchymal stromal cells, mineralization, tissue engineering, umbilical cord

Organism: Human

Cell Line: Dental pulp stem cells (DPSCs), Adipose tissue derived stem cells (ASCs)

128
Generation of human iPSCs from human prostate cancer-associated fibroblasts IBPi002-A

Zuzana Kahounová, Eva Slabáková, Lucia Binó, Ján Remšík, Radek Fedr, Jan Bouchal, Daniela Kurfűrstová, Radek Vrtěl, Vladimír Študent, Lucie Jurečková, Volodymyr Porokh, Aleš Hampl, Karel Souček

Stem Cell Research (Elsevier) Czech Republic, 16 November 2018

Stem Cell Research

Key words:induced stem cells, iPSCs, prostate fibroblasts, IBPi00-2

Organism: Human

Cell Line: Induced pluripotent cells (iPSCs)

129
Hepatocellular carcinoma-targeted nanoparticles for cancer therapy

Chien-Hsun Wu, Chun-Hsin Lan, Kuan-Lin Wu, Yao‑Ming Wu, Wann-Neng Jane , Michael Hsiao, Han-Chung Wu

International Journal of Oncology (Spandidos Publications) Taiwan, 16 November 2018

Oncology

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

130
Semi-Automated and Manual Methods for Counting Cells Expressing P75 Receptor in Endometriotic Lesions

Dewanto Agung, Sun Xiaoyan, Dudas Jozsef, Gluekert Rudolf, Schrott-Fischer Anneliese, W. D. Ludwig, Seeber Beata

() Indonesia, Austria, 12 November 2018

Cytometry

Key words:Observers,Immune system,Software,Lesions,Manuals,Biomedical imaging,Tools

131
Novel Protective Effects of Cistanche Tubulosa Extract Against Low-Luminance Blue Light-Induced Degenerative Retinopathy

Man-Ru Wua, Cheng-Hui Lina, Jau-Der Hob, George Hsiaoc, Yu-Wen Cheng

Cellular Physiology and Biochemistry (Karger) Taiwan, 07 November 2018

Ophthalmology

Key words:Cistanche tubulosa extract • Blue light • Apoptosis • Retinal pigment epithelial cells

Organism: Human

Cell Line: Retinal pigment epithelium cells (RPEs)

132
Increased frequency of systemic pro-inflammatory Vδ1+ γδ T cells in HIV elite controllers correlates with gut viral load

Gregory S. Olson, Sarah W. Moore, James M. Richter, John J. Garber, Brittany A. Bowman, Crystal A. Rawlings, Meaghan Flagg, Björn Corleis and Douglas S. Kwon

Scientific Reports (Nature) USA, 07 November 2018

Immunology, Virology

Key words:Chronic inflammation, Gammadelta T cells, HIV infections, Infection, Mucosal immunology

Organism: Human

Tissue: Small Intestine

Pathological State: Virus Infection

133
Loss of BAP1 expression is associated with genetic mutation and can predict outcomes in gallbladder cancer

Takashi Hirosawa, Masaharu Ishida , Kentaro Ishii, Keigo Kanehara, Katsuyoshi Kudo, Shinobu Ohnuma, Takashi Kamei, Fuyuhiko Motoi, Takeshi Naitoh, Florin M. Selaru, Michiaki Unno

PLOS ONE (PLOS) Japan, USA, 05 November 2018

Oncology

Key words:DNA methylation ,Small interfering RNAs ,Polymerase chain reaction ,Methylation ,Mutation detection ,Prognosis ,DNA sequence analysis ,Nonsense mutation

Organism: Human

Tissue: Gallbladder

Pathological State: Cancer

134
Genetic ablation of NFAT5/TonEBP in smooth muscle cells impairs flow- and pressure-induced arterial remodeling in mice

Caroline Arnold, Anja Feldner, Maren Zappe, Dorde Komljenovic, Carolina De La Torre, Philipp Ruzicka, Markus Hecker, Wolfgang Neuhofer, and Thomas Korff

The FASEB Journal (FASEB) Germany, 01 November 2018

Regenerative Medicine

Key words:hypertension, wall stress, transcriptome

Organism: Mouse

Cell Line: Primary aterial smooth muscle cells, vascular smooth muscle cells (VSMCs )

135
Tissue and host species-specific transcriptional changes in models of experimental visceral leishmaniasis

Helen Ashwin , Karin Seifert , Sarah Forrester , Najmeeyah Brown , Sandy MacDonald , Sally James , Dimitris Lagos , Jon Timmis , Jeremy C Mottram , Simon L. Croft , Paul M. Kaye

Wellcome Open Research (Wellcome Open Research) UK, 29 October 2018

Parasitology

Key words:Leishmania, infection, host response, transcriptomics, immunopathology

Organism: Mouse

Tissue: Spleen, Liver

Pathological State: Parasitic Infection

136
Azo-based small molecular hypoxia responsive theranostic for tumor-specific imaging and therapy

Ying Zhoua, Mrinmoy Maitib, Amit Sharmac, Miae Won, Le Yu, Lan Xi, Miao, Jinwoo Shin, Arup Podder, Kondapa Naidu Bobba, Jiyou Han, Sankarprasad Bhuniya, Jong Seung Kim

Journal of Controlled Release (Elsevier) China, India, South Korea, 28 October 2018

Oncology

Key words:molecular hypoxia, theranostic, tumor-specific imaging,

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

137
PI3K: A master regulator of brain metastasis‐promoting macrophages/microglia

Raquel Blazquez Darius Wlochowitz Alexander Wolff Stefanie Seitz Astrid Wachter Julia Perera‐Bel Annalen Bleckmann Tim Beißbarth Gabriela Salinas Markus J. Riemenschneider Martin Proescholdt Matthias Evert Kirsten Utpatel Laila Siam Bawarjan Schatlo Marko Balkenhol Christine Stadelmann Hans‐Ulrich Schildhaus Ulrike Korf Eileen Reinz Stefan Wiemann Elena Vollmer Mathias Schulz Uwe Ritter Uwe K. Hanisch Tobias Pukrop

GLIA (Wiley) Germany, 25 October 2018

Oncology

Key words:Astrocytes; BKM120; brain metastasis; macrophages; microglia; PI3K; RPPA

Organism: Mouse

Pathological State: Cancer

Cell Line: Monocyte‐derived macrophages (MDMs)

138
Alteration of mesenchymal stem cells polarity by laminar shear stimulation promoting β-catenin nuclear localization

Wei-TaChen, Wei-Tse Hsu, Meng-Hua Yen, Chun A. Changou, Chia-Li Han, Yu-Ju Chen, Ji-Yen Cheng, Tzu-Hao Chang, Oscar Kuang-Sheng Lee, Jennifer Hui-Chun Ho

Biomaterials (Elsevier) Taiwan, 23 October 2018

Stem Cell Research

Key words:β-catenin, Cardiovascular, Laminar shear, Mesenchymal stem cells, Wnt

Organism: Human

Cell Line: Human mesenchymal stem cells (hMSCs)

139
Gene expression profiling in a mouse model of Dravet syndrom

Nicole A.Hawkins, Jeffrey D.Calhoun, Alexandra M.Huffman, Jennifer A.Kearney

Experimental Neurology (Elsevier) USA, 19 October 2018

Neuroscience

Key words:Epilepsy; Epileptic encephalopathy; Gene expression; RNA-seq; Seizure; Voltage-gated sodium channel

Organism: Mouse

Tissue: Brain

Pathological State: Dravet Syndrome

140
Kinin-B2 Receptor Activity in Skeletal Muscle Regeneration and Myoblast Differentiation

Janaina M. Alves, Antonio H. Martins, Claudiana Lameu, Talita Glaser, Nawal M. Boukli, Vinicius Bassaneze, Rafael Dariolli, Isis C. Nascimento, Poliana C. M. Martins, Héllio D. N. de Souza, José Eduardo Krieger, Dulce E. Casarini, Vicencia M. Sales, João B. Pesquero, Henning Ulrich

Stem cell reviews and reports (Springer) USA, Brazil, 18 October 2018

Stem Cell Research

Key words:Mouse myoblast differentiation, Muscle repair, Kinin-B2 receptor, HOE-140

Organism: Mouse

Cell Line: Myoblast cell line - C2C12 Cells

141
Transforming growth factor beta 1 mediates the low-frequency vertical vibration enhanced production of tenomodulin and type I collagen in rat Achilles tendon

Chia-Hsin Chen, Yi-Hsiung Lin, Chung-Hwan Chen, Yan-Hsiung Wang, Ming-Long Yeh, Tsung-Lin Cheng, Chau-Zen Wang

PLOS ONE (PLOS) Taiwan, 11 October 2018

Cell Biology

Key words:Tendons ,Collagens ,Gene expression ,Stiffness ,Vibration ,Mechanical properties ,Enzyme-linked immunoassays ,Polymerase chain reaction

Organism: Rat

Tissue: Tendon

142
Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting

Mera vCohen, Amir Giladi, Anna-Dorothea Gorki, Dikla Gelbard Solodkin, Mor Zada, Anastasiya Hladik, Andras Miklosi, Tomer-Meir Salame, Keren Bahar Halpern, Eyal David, Shalev Itzkovitz, Tibor Harkany, Sylvia Knapp, Ido Amit

CELL (Cell Press) Israel, Austria, Sweden, 11 October 2018

Cell Biology

Key words:immune systemsingle-cell RNA sequencinglungbasophilsalveolar macrophagescellular interactiondevelopmentsignaling

Organism: Mouse

Tissue: Lung

143
Early Immunologic Response of Irreversible Electroporation versus Cryoablation in a Rodent Model of Pancreatic Cancer

Sarah B. White, MD, MS, FSIR, Zhouli Zhang, MD, PhD, Jeane Chen, PhD, Venkateswara R. Gogineni, PhD, and Andrew C. Larson, PhD

Journal of Vascular and Interventional Radiology (Elsevier) USA, 11 October 2018

Immunology

Key words:irreversible electroporation, Cryoablation, Pancreatic Cancer

Organism: Mouse

Pathological State: Cancer

Cell Line: PANC-2 (Pancreatic cancer cell line)

144
Inhibition of AKT suppresses the initiation and progression of BRCA1-associated mammary tumors

Hye Jung Baek, Sun Eui Kim, Jong Kwang Kim, Dong Hoon Shin, Tae Hyun Kim, Kwang Gi Kim, Chu-Xia Deng, Sang Soo Kim

International Journal of Biological Sciences (Ivyspring International Publisher) South Korea, China, 10 October 2018

Oncology

Key words:BRCA1, AKT, MK-2206, precision medicine

Organism: Mouse

Tissue: Breast

Pathological State: Cancer

145
Accelerated Aging and Clearance of Host Anti-inflammatory Enzymes by Discrete Pathogens Fuels Sepsis

Yang WH, Heithoff DM, Aziz PV, Haslund-Gourley B, Westman JS, Narisawa S, Pinkerton AB, Millán JL, Nizet V, Mahan MJ, Marth JD

Cell Host and Microbe (Cell Press) USA, 10 October 2018

Immunology, Microbiology

Key words:glycosylation, sepsis, neuraminidase, Toll-like receptor 4, alkaline phosphatase, Ashwell-Morell receptor, lipopolysaccharide, inflammation

Organism: Mouse

Tissue: Liver

Pathological State: Sepsis

146
Age, but not short-term intensive swimming, affects chondrocyte turnover in zebrafish vertebral cartilage

Quan-Liang Jian​, Wei-Chun HuangFu​, Yen-Hua Lee, I-Hsuan Liu​

The Journal of Life and Environmental Sciences (PeerJ) Taiwan, 01 October 2018

Osteology

Key words:Aging, Cartilage, Osteoarthritis, Tissue homeostasis, Chondrocyte

Organism: Fish

Tissue: Spinal Cord

147
Extracellular domain of EpCAM enhances tumor progression through EGFR signaling in colon cancer cells

Kang-Hao Liang, Hsien-Cheng Tso, Shao-Hsi Hung, I.-I. Kuan, Jun-Kai Lai, Feng-Yi Ke, Yi-Ting Chuang, I-Ju Liu, Yi-Ping Wang, Ruey-Hwa Chen, Han-Chung Wu

Cancer Letters (Elsevier) Taiwan, 01 October 2018

Oncology

Key words:Epithelial cell adhesion molecule, Regulated intramembrane proteolysis, β-catenin, HIF1α

Organism: Human

Tissue: Colon

Pathological State: Cancer

148
Gd-EOB-DTPA DCE-MRI biomarkers in a rabbit model of liver fibrosis

Yang Ji, Chuanshan Zhang, Zhe Huang, Xia Wang, Lina Yue, Meimei Gao, Huiling Hu, Qinjun Su, Yuedong Han, Bin Liu, Ding Yang, Zhanliang Su, Zhuoli Zhang

American Journal of Translational Research (e-Century Publishing Corporation) China, USA, 30 September 2018

Hepathology

Key words:Liver fibrosis, animal, magnetic resonance imaging, pathology

Organism: Rabbit

Tissue: Liver

Pathological State: Fibrosis, Liver Cirrhosis

149
Modified Ginseng Extract Induces Apoptosis in HepG2 Cancer Cells by Blocking the CXCL8-Mediated Akt/Nuclear Factor-κB Signaling Pathway

Zhen Yang Cui, Eunbi Jo, Hyun Jin Jang, In-Hu Hwang, Kyung-Bok Lee, Hwa-Seung Yoo, Soo Jung Park, Mi-Kyung Jung, Yeon Wol Lee and Ik-Soon Jang

The American Journal of Chinese Medicine (World Scientific) South Korea, 27 September 2018

Oncology

Key words:Modified Regular Ginseng Extract; MRGX; C-X-C Motif Chemokine Ligand 8; Liver Cancer; Akt; Nuclear Factor-κB; Apoptosis

Organism: Human

Pathological State: Cancer

Cell Line: HepG2 (Liver carcinoma cell line)

150
Development of Decellularized Cornea by Organic acid Treatment for Corneal Regeneration

Mr. HungJun Lin, Dr. TsungJen Wang, Miss TingWei Li, Dr. YaoYuan Chang, Prof. Ming Thau Sheu, Prof. Yi-You Huang, Dr. Der-Zen Liu

Tissue Engineering Part A (Mary Ann Liebert Inc.) Taiwan, 22 September 2018

Tissue Engineering

Key words:cornea; decellularized scaffold; extracellular matrix; xenograft; corneal transplantation.

Organism: Rabbit

Tissue: Eye

151
The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases

Bohumil Fafilek, Lukas Balek, Michaela Kunova Bosakova, Miroslav Varecha, Alexandru Nita, Tomas Gregor, Iva Gudernova, Jitka Krenova, Somadri Ghosh, Martin Piskacek, Lucie Jonatova, Nicole H. Cernohorsky, Jennifer T. Zieba, Michal Kostas, Ellen Margrethe Haugsten, Jørgen Wesche, Christophe Erneux, Lukas Trantirek, Deborah Krakow, and Pavel Krejc

Science Signaling (American Association for the Advancement of Science) Czech Republic, Belgium, USA, Norway, 18 September 2018

Cell Biology

Key words:SHIP2, ERK activation, FGF receptors, Src kinases

Organism: Rat, Human

Pathological State: Cancer

Cell Line: U2OS (Osteosarcoma cell line), RCS cells (Cultured rat chondrosarcoma cell line)

152
ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific manner

Jacqueline A. Brosnan-Cashman, Ming Yuan, Mindy K. Graham, Anthony J. Rizzo, Kaylar M. Myers, Christine Davis, Rebecca Zhang, David M. Esopi, Eric H. Raabe, Charles G. Eberhart, Christopher M. Heaphy, Alan K. Meeker

PLOS ONE (PLOS) USA, 18 September 2018

Oncology

Key words:Telomeres, Cloning, Glioma cells ,Glioma ,DNA cloning ,Immunoblotting ,Vector cloning ,Polymerase chain reaction

Organism: Human

Pathological State: Cancer

Cell Line: Glioma cell lines (MOG-G-UVW, SF188, U-251 and UW479)

153
Activation of estrogen receptor alpha induces beiging of adipocytes

Roberta S.Santos, Aaron P.Frank, Luciana A.Fátima, Biff F.Palmer, Deborah J.Clegg

Molecular Metabolism (Elsevier) USA, 15 September 2018

Cell Biology

Key words:Beige adipocytes, Lipolysis, Estrogen receptor alpha (ERα), Obesity, Type II diabetes mellitus (T2DM)

Organism: Mouse

Tissue: Adipose Tissue

154
Cellular-scale probes enable stable chronic subsecond monitoring of dopamine neurochemicals in a rodent model

Helen N. Schwerdt, Elizabeth Zhang, Min Jung Kim, Tomoko Yoshida, Lauren Stanwicks, Satoko Amemori, Huseyin E. Dagdeviren, Robert Langer, Michael J. Cima and Ann M. Graybiel

Communications Biology (Nature) USA,, 12 September 2018

Neuroscience

Key words:Diagnostic markers, Neurochemistry, Parkinson's disease, Sensors and probes

Organism: Rat

Tissue: Brain

155
Synthetic α5β1 integrin ligand PHSRN is proangiogenic and neuroprotective in cerebral ischemic stroke

Cheng-Chun Wu, Liang-Chao Wang, Yu-Tin Su, Wei-Yen Wie, Kuen-Jer Tsai

Biomaterials (Elsevier) Taiwan, 11 September 2018

Biological Materials

Key words:Stroke, Fibronectin, PHSRN, α5β1, Angiogensis, Neurogenesis, VEGF

Organism: Rat

Tissue: Brain

156
Phenethyl Isothiocyanate Inhibits In Vivo Growth of Xenograft Tumors of Human Glioblastoma Cells

Yu-Cheng Chou, Meng-Ya Chang, Hsu-Tung Lee, Chiung-Chyi Shen, Tomor Harnod, Yea-Jiuan Liang, Rick Sai-Chuen Wu, Kuang-Chi Lai, Fei-Ting Hsu, Jing-Gung Chung

Molecules (MDPI) Taiwan, 10 September 2018

Oncology

Key words:phenethyl isothiocyanate; apoptosis; xenograft; caspase; glioblastoma

Organism: Mouse

Tissue: Liver, Xenograft Tumor

Pathological State: Cancer

157
Factor Xa inhibition by rivaroxaban regulates fibrogenesis in human atrialfibroblasts with modulation of nitric oxide synthesis and calciumhomeostasis

Cheng-Chih Chung, Yung-Kuo Lin, Yao-Chang Chen, Yu-Hsun Kao, Yung-Hsin Yeh, Yi-Jen Chen

Journal of Molecular and Cellular Cardiology (Elsevier) Taiwan, 10 September 2018

Physiology

Key words:Fibroblasts, Fibrosis, Rivaroxaban, Protease-activated receptor, Atrial fibrillation, Stroke

Organism: Rat

Tissue: Heart

Pathological State: Fibrosis

158
Androgen receptor expression inversely correlates with immune cell infiltration in human epidermal growth factor receptor 2–positive breast cancer

Johan M. van Rooijen, Si-Qi Qiu, Hetty Timmer-Bosscha, Bert van der Vegt, James E. Boers, Carolien P. Schröder, Elisabeth G.E. de Vries

European Journal of Cancer (Elsevier) The Netherlands, China, 09 September 2018

Oncology

Key words:Androgen receptor expression, HER2-positive metastatic breast cancer, Immune cell infiltration, Trastuzumab resistance

Organism: Human

Tissue: Breast

Pathological State: Cancer

159
TLR7 agonist attenuates acetylcholine‐induced, Ca2+‐dependent ionic currents in swine tracheal submucosal gland cells

Shunichi Gamo, Tsutomu Tamada, Koji Murakami, Soshi Muramatsu, Hidemi Aritake, Masayuki Nara, Itsuro Kazama, Tatsuma Okazaki, Hisatoshi Sugiura, Masakazu Ichinose

Experimental Physiology (Wiley) Japan, 08 September 2018

Physiology

Key words:CaCC, COPD, hypersecretion, R837, submucosal glands

Organism: Pig, Human

Tissue: Lung, Spleen

160
Inhibitory control of prefrontal cortex by the claustrum

Jesse Jackson, Mahesh M. Karnani, Boris V. Zemelman, Denis Burdakov, Albert K. Lee

Neuron (Cell Press) USA, UK, Canada, 05 September 2018

Neuroscience

Key words:claustrum prefrontal NPY PV neocortex feed-forward inhibition microcircuit neurogliaform cell somatostatin interneuron VIP

Organism: Mouse

Tissue: Brain

161
Oxidized Low-Density Lipoprotein-Deteriorated Psoriasis Is Associated with the Upregulation of Lox-1 Receptor and Il-23 Expression In Vivo and In Vitro

Chun-Ming Shih, Chien-Yu Huang, Kuo-Hsien Wang, Chun-Yao Huang, Po-Li Wei, Yu-Jia Chang, Chi-Kun Hsieh, Kuan-Ting Liu, Ai-Wei Lee

International Journal of Molecular Sciences (MDPI) Taiwan, 03 September 2018

Dermatology

Key words:oxLDL; LOX-1; psoriasis

Organism: Mouse

Tissue: Skin

Pathological State: Psoriasis

162
Amentoflavone Inhibits Hepatocellular Carcinoma Progression Through Blockage of ERK/NF-ĸB Activation

Kun-Ching Lee, Wei-Ting Chen, Yu-Chang Liu, Song-Shei Lin, Fei-Ting Hsu

in vivo: international journal of experimental and clinical pathophysiology and drug research (International Institute of Anticancer Research) Taiwan, 01 September 2018

Oncology

Key words:Amentoflavone, hepatocellular carcinoma, extracellular signal-regulated kinase, nuclear factor-kappaB, bioluminescence imaging.

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

163
Enhanced Sternal Healing via Platelet-Rich Plasma and Biodegradable Gelatin Hydrogel

Masafumi Shibata, Gen Takagi, Mitsuhiro Kudo, Jiro Kurita, Yoko Kawamoto, Yasuo Miyagi, Mikimoto Kanazashi, Takashi Sakatani, Zenya Naito, Yasuhiko Tabata, Masaaki Miyamoto, and Takashi Nitta

Tissue Engineering Part A (Mary Ann Liebert Inc.) Japan, 01 September 2018

Tissue Engineering

Organism: Rabbit

Tissue: Bone

164
The tree shrew cerebellum atlas: Systematic nomenclature, neurochemical characterization and afferent projections

Rong‐Jun Ni Zhao‐Huan Huang Peng‐Hao Luo Xiao‐Hong Ma Tao Li Jiang‐Ning Zhou

Journal of Comparative Neurology (Wiley) China, 29 August 2018

Neuroscience

Key words:cerebellar nuclei, lobule fissure, inferior olive, Purkinje cell, calbindin, RRID: AB_476894

Organism: Treeshrew

Tissue: Brain

165
Focused Ultrasound-Induced Blood-Brain Barrier Opening Enhances GSK-3 Inhibitor Delivery for Amyloid-Beta Plaque Reduction

Po-Hung Hsu, Ya-Tin Lin, Yi-Hsiu Chung, Kun-Ju Lin, Liang-Yo Yang, Tzu-Chen Yen and Hao-Li Liu

Scientific Reports (Nature) Taiwan, 27 August 2018

Neuroscience

Key words:Alzheimer's diseas, eBiomedical engineering ,Blood–brain barrier, Drug delivery, Translational research, GSK-3, Amyloid-Beta Plaque

Organism: Mouse

Tissue: Brain

Pathological State: Alzheimer’s Disease

166
NFAT5 isoform C controls biomechanical stress responses of vascular smooth muscle cells

Maren Zappe, Anja Feldner, Caroline Arnold, Carsten Sticht, Markus Hecker and Thomas Korff

Frontiers in Physiology (Frontiers Media S.A.) Germany, 23 August 2018

Cardiology

Key words:NFAT5; TonEBP; hypertension; transcriptional regulation; vascular smooth muscle cells; wall stress

Organism: Human

Cell Line: Human arterial smooth muscle cells (HUASMCs)

167
Role of the orexin 2 receptor in palatable-food consumption-associated cardiovascular reactivity in spontaneously hypertensive rats

Shang-Cheng Huang, Tzu-Ling Li, Yen-Hsien Lee, Yu-Wen E. Dai, Yu-Chun Chen Ling-Ling Hwang

Scientific Reports (Nature) Taiwan, 23 August 2018

Cardiology

Key words:Hypertension, Hypothalamus

Organism: Rat

Tissue: Brain

168
Lack of DNA damage response at low radiation doses in adult stem cells contributes to organ dysfunction

Peter W Nagle, Nynke A Hosper, Lara Barazzuol, Anne L Jellema, Mirjam Baanstra, Marc-Jan van Goethem, Sytze Brandenburg, Ulrich Giesen, Johannes A. Langendijk, Peter van Luijk and Rob P Coppes

Clinical Cancer Research (AACR Publications) The Netherlands, 22 August 2018

Oncology

Key words:DNA Damage, Radiation, Stem Cells, Organ Dysfunction, Radiotherapy

Organism: Mouse

Tissue: Thyroid, Salivary Gland

169
Modified Methacrylate Hydrogels Improve Tissue Repair after Spinal Cord Injury

Aleš Hejčl OrcID, Jiří Růžička, Kristýna Kekulová 1OrcID, Barbora Svobodová, Vladimír Proks OrcID, Hana Macková , Kateřina Jiránková , Kristýna Kárová , Lucia Machová Urdziková, Šárka Kubinová, Jiří Cihlář , Daniel Horák and Pavla Jendelová

International Journal of Molecular Sciences (MDPI) Czech Republic, 22 August 2018

Regenerative Medicine

Key words:spinal cord injury; hydrogel; connective tissue; neurofilaments; locomotor test; plantar test

Organism: Rat

Tissue: Spinal Cord

Pathological State: Spinal Cord Injury

170
Optimization of an Anti-NMDA Receptor Autoantibody Diagnostic Bioassay

NC Chiu, YJ Lin, RF Tzang, YS Li, HJ Lin, S Das, CG Chen, CC Chen, K Hsu

Circulation (NCBI) Taiwan, Denmark, Sweden, 22 August 2018

Neuroscience

Key words:Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis, autoantibody (autoAb), autoimmune encephalitis, schizophrenia, diagnostic test, fluorescein isothiocyanate (FITC), Alexa Fluor 488, antigen (Ag)

Organism: Human

Tissue: Blood

Pathological State: Encephalitis

171
Photoperiodic Flower Mimicking Metallic Nanoparticles for Image-Guided Medicine Applications

S Cho, B Lee, W Park, X Huang, DH Kim

Applied Materials and Interfaces (ACS Publications) USA, 22 August 2018

Radiotherapy

Key words:metallic nanoparticles; radiosensitizers; image-guided radiotherapy; radiation; cancer therapy

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

172
Striatal Microstimulation Induces Persistent and Repetitive Negative Decision-Making Predicted by Striatal Beta-Band Oscillation

Ken-ichi Amemori, Satoko Amemori,Daniel J. Gibson and Ann M. Graybie

Neuron (Cell Press) USA, 22 August 2018

Neuroscience

Key words:approach-avoidance conflict; basal ganglia; beta oscillation; caudate nucleus; cost-benefit decisions; emotion; macaque; motivation; primate; value judgment

Organism: Pig, Human

Tissue: Brain

173
Secreted products of oral bacteria and biofilms impede mineralization of apical papilla stem cells in TLR-, species-, and culture-dependent fashion

Xenos Petridis,Luc W. M. van der Sluis,1 René J. B. Dijkstra,1 Marja G. L. Brinker, Henny C. van der Mei,and Martin C. Harmsen

Scientific Reports (Nature) The Netherlands, 21 August 2018

Immunology, Microbiology

Key words:Mesenchymal stem cells, Oral diseases, biofilms

Organism: Human

Cell Line: SCAP (Stem cells from apical papilla)

174
Cbl-b deficiency provides protection against UVB-induced skin damage by modulating inflammatory gene signature

Tej Pratap Singh,Pablo A. Vieyra-Garcia,Karin Wagner,Josef Penninger,Peter Wolf

Cell Death and Disease (Nature) Austria, 06 August 2018

Oncology

Key words:Cbl-b deficiency, UVB, skin damage, inflammation, gene signature

Organism: Mouse, Human

Tissue: Skin

175
Expression and modulation of S100A4 protein by human mast cells

Rossana Domenis, David Pilutti, Maria Orsaria, Stefania Marzinotto, Veronica Candotti, Giulia Bosisio, Michela Bulfoni, Maria Elisabetta Ruaro, Carla Di Loreto, Vincenzo Della Mea, Eleonora Toffoletti, Ambrogio P.Londero, Laura Mariuzzi, Giorgia Gri

Cellular Immunology (Elsevier) Italy, 04 August 2018

Immunology

Key words:Immunofluorescence Tryptase Metalloproteinase Mast cells biology siRNA

Organism: Human

Tissue: Bladder, Skin

Pathological State: Bladder Cyst, Crohn's Disease, Cancer

176
Degeneration of white matter and gray matter revealed by diffusion tensor imaging and pathological mechanism after spinal cord injury in canine

Chang‐Bin Liu De‐Gang Yang Xin Zhang Wen‐Hao Zhang Da‐Peng Li Chao Zhang Chuan Qin Liang‐Jie Du Jun Li Feng Gao Jie Zhang Zhen‐Tao Zuo Ming‐Liang Yang Jian‐Jun Li

CNS Neuroscience and Therapeutics (Wiley) China, 03 August 2018

Neuroscience

Key words:canine model; diffusion tensor imaging; gray matter; pathological degeneration; spinal cord injury; white matter

Organism: Dog

Tissue: Spinal Cord

Pathological State: Spinal Cord Injury

177
Crumpled Aluminum Hydroxide Nanostructures as a Microenvironment Dysregulation Agent for Cancer Treatment

MI Lerner, G Mikhaylov, AA Tsukanov, Aleksandr S. Lozhkomoev, Elazar Gutmanas, Irena Gotman, Andreja Bratovs, Vito Turk‡ Boris Turk, Sergey G. Psakhye, and Olga Vasiljeva

Nano Letters (ACS Publications) Russia, Israel, Slovenia, 02 August 2018

Nanomedicine

Key words:aluminum hydroxide; cancer treatment; Crumpled nanosheets; ion balance; molecular dynamics simulation; tumor microenvironment

Organism: Mouse

Tissue: Allograft Tumor

Pathological State: Cancer

178
Plk1 overexpression induces chromosomal instability and suppresses tumor development

Guillermo de Cárcer,corresponding author Sharavan Vishaan Venkateswaran,Lorena Salgueiro,Aicha El Bakkali, Kalman Somogyi,Konstantina Rowald,Pablo Montañés,Manuel Sanclemente,Beatriz Escobar,Alba de Martino,4 Nicholas McGranahan,5 Marcos Malumbres,corresponding author1 and Rocío Sotillo

Nature Communications (Nature) Spain, 01 August 2018

Oncology

Key words:Cancer, Cell biology, Plk1, chromosomal instability

Organism: Mouse

Tissue: Liver, Pancreas, Kidney, Small Intestine, Lung

179
Plk1 overexpression suppresses tumor development by inducing chromosomal instability

Guillermo de Cárcer, Sharavan Vishaan Venkateswaran, Lorena Salgueiro, Aicha El Bakkali, Kalman Somogyi, Konstantina Rowald, Pablo Montañés, Manuel Sanclemente, Beatriz Escobar, Alba de Martino, Nicholas McGranahan, Marcos Malumbres and Rocío Sotillo

Nature Communications (Nature) Spain, Germany, UK, 01 August 2018

Oncology

Key words:Cancer, Cell biology

Organism: Mouse

Tissue: Breast

Pathological State: Cancer

180
SCID/NOD mice model for 5-FU induced intestinal mucositis: Safety and effects of probiotics as therapy

LawrenceHuangabJen-ShiuChiang ChiaucMei-LienChengcWai-TaoChanaChuen-BinJiangadSzu-WenChangaChun-YanYeungaeHung-ChangLee

Pediatrics and Neonatology (Elsevier) Taiwan, 26 July 2018

Gastroenterology

Key words:SCID; cytokines; fluorouracil; mucositis; probiotics

Organism: Mouse

Tissue: Small Intestine

Pathological State: Diarrhea

181
CRISPR-Cas9 Screens Reveal Genes Regulating a G0-like State in Human Neural Progenitors

Heather M Feldman, Chad M Toledo, Sonali Arora, Pia Hoellerbauer, Philip Corrin, Lucas Carter, Megan Kufeld, Hamid Bolouri, Ryan Basom, Jeffrey Delrow, Joshua Meier, Feng Zhang, José L. McFaline-Figueroa, Cole Trapnell, Steven M Pollard, Christopher L Plaisier, Patrick J Paddison

The Journal of thoracic and cardiovascular surgery (Elsevier) , 25 July 2018

182
Trehalose to cryopreserve human pluripotent stem cells

Aikaterini Ntaia , Alberto La Spadab , Pasquale De Blasioa , Ida Biunno

Stem Cell Research (Elsevier) Italy, 25 July 2018

Stem Cell Research

Key words:Cryopreservation, Trehalose, Pluripotent stem cells

Organism: Human

Cell Line: hESCs, lt-NES, hiPSCs

183
Depletion of Sirt3 leads to the impairment of adipogenic differentiation and insulin resistance via interfering mitochondrial function of adipose-derived human …

YT Wu, KT Chi, YW Lan, JC Chan, YS Ma, YH Wie

Free Radical Research (Taylor and Francis) Taiwan, 23 July 2018

Stem Cell Research

Key words:Adipogenesis, antioxidant defence, human mesenchymal stem cells, insulin resistance, mitochondrial bioenergetics, Sirt3

Organism: Human

Cell Line: adiposederived human mesenchymal stem cells

184
Succinate Accumulation Is Associated with a Shift of Mitochondrial Respiratory Control and HIF-1α Upregulation in PTEN Negative Prostate Cancer Cells

Anja Weber,Helmut Klocker,Herbert Oberacher,Erich Gnaiger,Hannes Neuwirt,Natalie Sampson and Iris E. Eder

International Journal of Molecular Sciences (MDPI) Austria, 21 July 2018

Oncology

Key words:Na+-dicarboxylate transporter; acidic tumor microenvironment; mitochondria; oxidative phosphorylation; prostate cancer; succinate

Organism: Human

Pathological State: Cancer

Cell Line: LNCaP, PC-3 (prostate cancer cell lines)

185
Prognostic and predictive values of immune infiltrate in patients with head and neck squamous cell carcinoma

Xue-MeiZhang Ling-JunSong JuanShenHao YueYa-QinHanChen LingYangShi YunLiuJia WenDengYue JiangGuo HuiFu

Human Pathology (Elsevier) China, 20 July 2018

Oncology

Key words:Head and Neck Squamous Cell Carcinoma; Immunoscore; Prognosis and Predictive; Tumor Infiltrating Lymphocytes

Organism: Human

Tissue: Head, Neck

Pathological State: Cancer

186
Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion

Mario Mauthe, Idil Orhon, Cecilia Rocchi, Xingdong Zhou, Morten Luhr, Kerst-Jan Hijlkema, Robert P. Coppes, Nikolai Engedal, Muriel Mari and Fulvio Reggiori

Autophagy (Taylor and Francis) The Netherlands, 20 July 2018

Cell Biology

Key words:Autophagy; Golgi; bafilomycin A1; degradative compartments; fusion; lysosomal degradation; lysosomal inhibitors

Organism: Human

Pathological State: Cancer

Cell Line: U2OS (Osteosarcoma cell line), HeLa cells

187
Significant therapeutic effects of adult human multipotent neural cells on spinal cord injury

KH Lee, HJ Pyeon, H Nam, JS Won, JY Hwang, KA Lee, JY Yeon, SC Hong, DH Nam, K Lee, SH Lee, KM Joo

Stem Cell Research (Elsevier) South Korea, 19 July 2018

Stem Cell Research

Key words:Spinal cord injuries, Adult stem cells, Neural stem cells, Microvasculature, Chemokine1

Organism: Rat

Tissue: Spinal Cord

Pathological State: Spinal Cord Injury

188
Trop-2 plasticity is controlled by epithelial-to-mesenchymal transition

Ján Remšík Lucia Binó Zuzana Kahounová Gvantsa Kharaishvili Šárka Šimečková Radek Fedr Tereza Kučírková Sára Lenárt Ximena Maria Muresan Eva Slabáková

Carcinogenesis (Oxford University Press) Czech Republic, 16 July 2018

Oncology

Key words:phenotype, cancer, carcinoma, epithelium, heterogeneity, antigens, cell lines, membrane glycoproteins, breast, neoplasms, prostate, transcription factor, prostate cancer, carcinogenesis, e-cadherin, tumor progression, epithelial to mesenchymal transition, molecular targeted therapy, tumor cells, malignant

Organism: Human

Tissue: Prostate, Breast

Pathological State: Cancer

189
Enhancement of chondrogenesis of adipose-derived stem cells in HA-PNIPAAm-CL hydrogel for cartilage regeneration in rabbits

Chau-Zen Wang,Rajalakshmanan Eswaramoorthy,Tzu-Hsiang Lin,Chung-Hwan Chen,Yin-Chih Fu,Chih-Kuang Wang,Shun-Cheng Wu,Gwo-Jaw Wang, Je-Ken Chang,corresponding author Mei-Ling Ho

Scientific Reports (Nature) Taiwan, 12 July 2018

Tissue Engineering

Key words:Biomaterials, Regeneration, hydrogel, cartilage

Organism: Rabbit

Cell Line: rADSCs (rabbit adipose-derived stem cells )

190
Expression of serine peptidase inhibitor Kunitz type 1 in differentiated thyroid cancer

Chien-Liang LiuPo-Sheng YangMing-Nan ChienYuan-Ching ChangChi-Hsin LinShih-Ping Cheng

Histochemistry and Cell Biology (Springer) Taiwan, 10 July 2018

Oncology

Key words:Serine protease inhibitor , Hepatocyte growth factor , Thyroid cancer Invasion

Organism: Human

Tissue: Thyroid

Pathological State: Cancer

191
Synergistic Cross‐Talk of Hedgehog and Interleukin‐6 Signaling Drives Growth of Basal Cell Carcinoma

Christina Sternberg Wolfgang Gruber Markus Eberl Suzana Tesanovic Manuela Stadler Dominik P. Elmer Michaela Schlederer Sandra Grund Simone Roos

International Journal of Cancer (Wiley) Austria, 10 July 2018

Oncology

Key words:GLI signaling ; GLI transcription factors ; STAT transcription factors; basal cell carcinoma ; hedgehog; interleukin-6 signaling

Organism: Mouse

Tissue: Allograft Tumor

Pathological State: Cancer

192
TERT Promoter Mutations in Solitary Fibrous Tumor

Elizabeth G Demicco Khalida Wani Davis Ingram Michael Wagner Robert G. Maki Anthony Rizzo Alan Meeker Alexander J Lazar Wei‐Lien Wang

HistoPathology (Wiley) USA, 09 July 2018

Oncology

Key words:ATRX ; DAXX ; metastasis; outcome; prognosis; risk assessment; solitary fibrous tumour; telomerase reverse transcriptase

Organism: Human

Pathological State: Cancer

193
Development of a Novel Orthogonal Double Gradient for High‐Throughput Screening of Mesenchymal Stem Cells–Materials Interaction

Qihui Zhou Lu Ge Carlos F. Guimarães Philipp T. Kühn Liangliang Yang Patrick van Rijn

Advanced Materials Interfaces (Wiley) The Netherlands, 04 July 2018

Biological Materials

Key words:high‐throughput screening, orthogonal double gradient, stem cell, stiffness, wettability

Organism: Human

Cell Line: Mesenchymal stem cells from human bone marrow (hBM-MSCs)

194
Benzyl isothiocyanate inhibits human brain glioblastoma multiforme GBM 8401 cell xenograft tumor in nude mice in vivo

Yi‐Shih Ma Jen‐Jyh Lin Chin‐Chung Lin Jin‐Cherng Lien Shu‐Fen Peng Ming‐Jen Fan Fei‐Ting Hsu Jing‐Gung Chung

Environmental Toxicology (Wiley) Taiwan, 04 July 2018

Oncology

Key words:benzyl isothiocyanate; human brain glioblastoma multiforme GBM 8401 cell; in vivo; nude mice; xenograft tumor

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

195
Antrodia cinnamomea produces anti-angiogenic effects by inhibiting the VEGFR2 signaling pathway

Tsung-TengHuang Ying-WeiLan Yun-FeiKo Chuan-MuChen Hsin-ChihLaijkDavid M.Ojcius JanMartel John D.Young Kowit-YuChong

Journal of Ethnopharmacology (Elsevier) Taiwan, 28 June 2018

Cell Biology

Key words:Antrodia cinnamomea, Anti-angiogenic activity, Endothelial cells, VEGFR2, STAT3

Organism: Mouse

Tissue: Lung

Pathological State: Cancer

196
Dynamics of tissue ingrowth in SIKVAV-modified highly superporous PHEMA scaffolds with oriented pores after bridging a spinal cord transection

Aleš Hejčl, Jiří Růžička Vladimír Proks, Hana Macková, Šárka Kubinová Dmitry Tukmachev,Jiří Cihlář Daniel Horák Pavla Jendelová

Journal of Materials Science: Materials in Medicine (Springer) Czech Republic, 25 June 2018

Regenerative Medicine

Key words:tissue ingrowth, SIKVAV, superporous, PHEMA scaffolds, oriented pores, spinal cord injury, mesenchymal stem cells (MSCs)

Organism: Rat

Tissue: Spinal Cord

Pathological State: Spinal Cord Injury

197
Neuroplastic change of cytoskeleton in inferior colliculus after auditory deafferentation

Jae JoonHanaHo SunLeebcMin-HyunPark

Hearing Research (Elsevier) South Korea, 23 June 2018

Neuroscience

Key words:Auditory deafferentation, Deafness, SMI-32, Neurofilament heavy chain, Inferior colliculus

Organism: Rat

Tissue: Brain

Pathological State: Deafness

198
Androgen excess in pancreatic β cells and neurons predisposes female mice to type 2 diabetes

Guadalupe Navarro, Camille Allard, Jamie J. Morford, Weiwei Xu, Suhuan Liu, Adrien J.R. Molinas, Sierra M. Butcher, Nicholas H.F. Fine, Manuel Blandino-Rosano, Venkata N. Sure, Sangho Yu, Rui Zhang, Heike Münzberg, David A. Jacobson, Prasad V. Katakam,David J. Hodson, Ernesto Bernal-Mizrachi, Andrea Zsombok,and Franck Mauvais-Jarvis

The Journal of Clinical Investigation (American Society for Clinical Investigation) USA, 21 June 2018

Oncology

Key words:Beta cells; Diabetes; Endocrinology; Metabolism; Sex hormones

Organism: Mouse

Tissue: Pancreas

Pathological State: Diabetes

199
Afatinib restrains K-RAS–driven lung tumorigenesis

Herwig P. Moll, Klemens Pranz, Monica Musteanu, Beatrice Grabner, Natascha Hruschka, Julian Mohrherr

Science Translational Medicine (American Association for the Advancement of Science) Austria, 20 June 2018

Oncology

Key words:Afatinib, K-RAS, lung cancer, pan-ERBB, tyrosine kinase inhibitors

Organism: Mouse

Tissue: Lung

Pathological State: Cancer

200
Competition between TIAM1 and Membranes Balances Endophilin A3 Activity in Cancer Metastasis

Kumud R.Poudel MinnaRoh-Johnson AllenSu ThuongHo HarithaMathsyaraja SarahAnderson William M.Grady Cecilia B.Moens MaraliceConacci-Sorrell Robert N.Eisenman

Developmental Cell (Cell Press) USA, 18 June 2018

Oncology

Key words:BAR domain; PTEN; Rac1; TIAM1; cell migration; endocytosis; endophilin; membrane remodeling; metastasis

Organism: Mouse

Tissue: Whole Organism

Pathological State: Cancer

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