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Customer Publications (A total of 1249 papers published)

01
The Role of Lysophosphatidic Acid on Airway Epithelial Cell Denudation in a Murine Heterotopic Tracheal Transplant Model

Yukiko Tando, Chiharu Ota, Mitsuhiro Yamada, Satoshi Kamata, Mutsuo Yamaya, Kuniyuki Kano, Shinichi Okudaira, Junken Aoki, and Hiroshi Kubo,

Transplantation (NCBI) Japan, 19 October 2019

Transplantation Medicine

Key words:Lysophosphatidic Acid, Airway Epithelial Cells, Denudation, Murine Heterotopic Tracheal Transplant Model

Organism: Mouse

Cell Line: BEAS-2B cells

02
Au Nanoparticles with Enzyme-Mimicking Activities Ornamented ZIF-8 for Highly Efficient Photodynamic Therapy

Y Ma, Y Zhu, XF Tang, L Hang, W Jiang, M Li, M Khan, YZ You, YC Wang

Biomaterials Science (Royal Society of Chemistry) China, 04 April 2019

Nanomedicine

Key words:AuNPs nanozyme, nano metal-organic frameworks, tumor hypoxia, photodynamic therapy

Organism: Mouse

Tissue: Breast

Pathological State: Cancer

03
The sodium–glucose co-transporter 2 inhibitor empagliflozin attenuates cardiac fibrosis and improves ventricular hemodynamics in hypertensive heart failure …

Hsiang-Chun Lee, Yi-Lin Shiou, Shih-Jie Jhuo, Chia-Yuan Chang, Po-Len Liu, Wun-Jyun Jhuang, Zen-Kong Dai, Wei-Yu Chen, Yun-Fang Chen and An-Sheng Lee

Cardiovascular Diabetology (BMC) Taiwan, 01 April 2019

Cardiology

Key words:SGLT2 inhibitor Empagliflozin Hypertensive Heart failure Cardiac fibrosis Hemodynamics High-fat PPARα ACADM

Organism: Rat

Tissue: Heart

Pathological State: Fibrosis

04
Antrodia cinnamomea induces anti-tumor activity by inhibiting the STAT3 signaling pathway in lung cancer cells

TT Huang, YW Lan, CM Chen, YF Ko, DM Ojcius, J Martel, JD Young, KY Chong

Scientific reports (Nature) Taiwan, USA, Malaysia, 26 March 2019

Oncology

Key words:Drug development, Lung cancer

Organism: Mouse

Tissue: Lung

05
Designing pH-Triggered Drug Release Iron Oxide Nanocomposites for MRI Guided Photothermal-Chemoembolization Therapy of Liver Orthotopic Cancer

F Liu, X Li, Y Li, Y Qi, H Yuan, J He, W Li, M Zhou

Biomaterials Science (Royal Society of Chemistry) China, 19 March 2019

Nanomedicine

Key words:pH-Triggered Drug Release, Iron Oxide Nanocomposites, MRI, Photothermal-Chemoembolization Therapy, Liver Orthotopic Cancer

Organism: Rat

Tissue: Liver

Pathological State: Cancer

06
γδT cells suppress liver fibrosis via strong cytolysis and enhanced NK cell-mediated cytotoxicity against hepatic stellate cells

M Liu, Y Hu, Y Yuan, Z Tian, C Zhang

Frontiers in Immunology (Frontiers Media S.A.) China, Germany, Belgium, USA, 15 March 2019

Immunology

Key words:fibrosis, γδT cell, NKp46, cytotoxicity, γδT1, γδT17, CD137, cell crosstalk

Organism: Mouse

Tissue: Liver

Pathological State: Fibrosis

07
Traffic-related particulate matter exposure induces nephrotoxicity in vitro and in vivo

YH Hsu, HC Chuang, YH Lee, YF Lin, YJ Chen, TC Hsiao, MY Wu, HW Chiu

Free Radical Biology and Medicine (Elsevier) Taiwan, 14 March 2019

Toxicology

Key words:Nephrotoxicity, Autophagy, Apoptosis, Endoplasmic reticulum stress

Organism: Rat

Tissue: Kidney

08
ErbB3 Ligand Heregulin1 Is a Major Mitogenic Factor for Uncontrolled Lung Cancer Cell Proliferation

S Ma, S Jia, Y Ren, B Cao, X Zha, J He, C Chen

Neoplasia (Elsevier) China, 02 March 2019

Oncology

Key words:ErbB3 , Heregulin1, Lung Cancer

Organism: Human

Tissue: Lung

Pathological State: Cancer

09
High-risk human papillomavirus oncogenes disrupt the Fanconi anemia DNA repair pathway by impairing localization and de-ubiquitination of FancD2

S Khanal, DA Galloway

PLoS Pathogens (PLOS) USA, 28 February 2019

Virology

Key words:Immunoblotting, Oncogenes, DNA repair, Phosphorylation, Human papillomavirus, HPV-16, Cell signaling, Small interfering RNAs

Organism: Human

Pathological State: Virus Infection

Cell Line: Primary human foreskin keratinocytes (HFKs)

10
Expression of the neonatal Fc-receptor in placental-fetal endothelium and in cells of the placental immune system

T Kiskova, Y Mytsko, M Schepelmann, H Helmer, R Fuchs, M Heidi, C Wadsack, I Ellinger

Placenta (Elsevier) Austria, 28 February 2019

Reproductive Medicine

Key words:Human placenta, FcRn, syncytiotrophoblast, placental-fetal endothelial cells, placental macrophages, IgG transport

Organism: Human

Tissue: Placenta

11
Metabolic cross-talk between human bronchial epithelial cells and internalized Staphylococcus aureus as a driver for infection

Laura M. Palma Medina, Ann-Kristin Becker, Stephan Michalik, Harita Yedavally, Elisa J.M. Raineri, Petra Hildebrandt, Manuela Gesell Salazar, Kristin Surmann, Henrike Pförtner, Solomon A. Mekonnen, Anna Salvati, Lars Kaderali, Jan Maarten van Dijl and U

Molecular & Cellular Proteomics (ASBMB) Germany, The Netherlands,, 26 February 2019

Immunology

Key words:Staphylococcus aureus, in vivo proteomics, population heterogeneity, persister, bronchial epithelial cells, Apoptosis*, Autophagy Bacteria, Energy metabolism, Host-Pathogen Interaction, Infectious disease

Organism: Human

Pathological State: Bacterial Infection

Cell Line: Bronchial epithelial cells

12
Ligase 3–mediated end-joining maintains genome stability of human embryonic stem cells

Aneta Kohutova, Jan Raška, Miriama Kruta, Monika Seneklova, Tomas Barta, Petr Fojtik, Tereza Jurakova, Christi A. Walter, Ales Hampl, Petr Dvorak, and Vladimir Rotrekl

FASEB Journal (FASEB) Czech Republic, USA, 26 February 2019

Stem Cell Research

Key words:base excision repair, PARP1, 53BP1, pluripotent stem cells, alternative DNA end-joining

Organism: Human

Cell Line: human embryonic stem cells

13
Higher CXCL16 exodomain is associated with aggressive ovarian cancer and promotes the disease by CXCR6 activation and MMP modulation

H Mir, G Kaur, N Kapur, S Bae, JW Lillard, S Singh

Scientific reports (Nature) USA, 21 February 2019

Oncology

Key words:Cancer, Ovarian cancer

Organism: Human

Tissue: Ovaries

Pathological State: Cancer

14
State-of-the-Art of Profiling Immune Contexture in the Era of Multiplexed Staining and Digital Analysis to Study Paraffin Tumor Tissues

ER Parra, A Francisco-Cruz, II Wistuba

Cancers (MDPI) USA, 20 February 2019

Medical Image Analysis

Key words:immune profiling; cancer tissues; multiplexed methodologies; image analysis; spatial analysis

15
Long noncoding RNA AOC4P regulates tumor cell proliferation and invasion by epithelial–mesenchymal transition in gastric cancer

K Zhang, C Lu, X Huang, J Cui, J Li, Y Gao, W Liang, Y Liu, Y Sun, H Liu, B Wei, L Chen

Therapeutic Advances In Gastroenterology (SAGE Journals) China, 19 February 2019

Oncology

Key words:AOC4P, long noncoding RNAs, metastasis, prognosis, stomach neoplasm

Organism: Human

Tissue: Stomach

Pathological State: Cancer

16
B-type natriuretic peptide enhances fibrotic effects via matrix metalloproteinase-2 expression in the mouse atrium in vivo and in human atrial myofibroblasts in vitro

YT Tsai, FY Lin, CS Lin, SH Loh, CY Li, CY Lin, YW Lin, CS Tsai

Translational Research (Elsevier) Taiwan, 19 February 2019

Cardiology

Key words:B-type natriuretic peptide; atrial fibrillation; matrix metalloproteinase

Organism: Mouse

Tissue: Heart

17
Ultralong circulating choline phosphate liposomal nanomedicines for cascaded chemo-radiotherapy

X Li, Y Zhao, W Jiang, S Li, M Zhan, H Liu, C Zhang, H Liang, H Liu, L Lu, Y Wang

Biomaterials Science (Royal Society of Chemistry) China, 14 February 2019

Nanomedicine

Key words:Cascaded chemo-radiotherapy, hypoxia-activated therapy, tumor hypoxia, ultralong circulating liposome

Organism: Mouse

Tissue: Allograft Tumor

Pathological State: Cancer

18
The Accumulation and Effects of Liposomal Doxorubicin in Tissues Treated by Radiofrequency Ablation and Irreversible Electroporation in Liver: In Vivo Experimental …

T Andrašina, J Jaroš, T Jůza, T Rohan, D Červinka, M Crha, V Válek, NS Goldberg

Cardiovascular and Interventional Radiology (Springer) Czech Republic, Israel, 13 February 2019

Hepathology

Key words:Liposomal doxorubicin, Radiofrequency ablation, Irreversible electroporation

Organism: Pig

Tissue: Liver

19
Tumoral EHF predicts the efficacy of anti-PD1 therapy in pancreatic ductal adenocarcinoma

Jing Liu, Wenna Jiang, Kaili Zhao, Hongwei Wang, Tianxing Zhou, Weiwei Bai, Xiuchao Wang, Tiansuo Zhao, Chongbiao Huang, Song Gao, Tai Qin, Wenwen Yu, Bo Yang, Xin Li, Danqi Fu, Wei Tan, Shengyu Yang, He Ren, Jihui Hao

Journal of Experimental Medicine (Rockefeller University Press) China, USA, 07 February 2019

Oncology

Key words:EHF, anti-PD1 therapy, adenocarcinoma, pancreas

Organism: Human

Tissue: Pancreas

Pathological State: Cancer

20
Generation of human iPSCs from fetal prostate fibroblasts HPrF

Zuzana Kahounová, Eva Slabáková, Lucia Binó, Ján Remšík, Radek Fedr, Jan Bouchal, Radek Vrtěl, Lucie Jurečková, Volodymyr Porokh, Darja Páralová, Aleš Hampl, Karel Souček

Stem Cell Research (Elsevier) Czech Republic, 07 February 2019

Stem Cell Research

Key words:induced stem cells, iPSCs, prostate fibroblasts, HPrF

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

21
Fluorine-Modified Rutaecarpine Exerts Cyclooxygenase-2 Inhibition and Anti-inflammatory Effects in Lungs

CM Lee, JH Liao, SH Chen, CH Yen, YC Lee, S Huang, S Huang, C Lin, VH Chang

Frontiers in Pharmacology (Frontiers Media S.A.) Taiwan, 07 February 2019

Pulmonology

Key words:Fluorine, Rutaecarpine, Cyclooxygenase-2 , Anti-inflammatory Effects

Organism: Mouse

Tissue: Whole Organism

22
Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade

CCS Pai, JT Huang, X Lu, DM Simons, C Park…

Immunity (Cell Press) USA, 05 February 2019

Oncology

Key words:cancer immunotherapy IFN-γ activation-induced cell death anti-CTLA-4 anti-PD-1

Organism: Mouse

Tissue: Allograft Tumor

Pathological State: Cancer

23
EphB2-dependent signaling promotes neuronal excitotoxicity and inflammation in the acute phase of ischemic stroke

Anne-Sophie Ernst, Laura-Inés Böhler, Anna M. Hagenston, Angelika Hoffmann, Sabine Heiland, Carsten Sticht, Martin Bendszus, Markus Hecker, Hilmar Bading, Hugo H. Marti1, Thomas Korff and Reiner Kunze

Acta Neuropathologica (BMC) Germany, 05 February 2019

Neuroscience

Key words:EphB2, Ephrin-B2, Excitotoxicity, Inflammation, Ischemic stroke, NMDA

Organism: Mouse

Tissue: Brain

Pathological State: Cerebral Ischemia

24
Hypoxic changes to the urothelium as a bystander of end-stage bladder disease

Anna Radford, Dr Jenny Hinley, Dr Alice Pilborough, Jennifer Southgate, Ramnath Subramaniam

Journal of Pediatric Urology (Elsevier) UK, 05 February 2019

Urology

Key words:Neuropathic bladder, Hypoxia, Hypoxia-inducible factor1 alpha, Obstruction, Regenerative medicine

Organism: Human

Tissue: Bladder

Pathological State: Neuropathy

25
Spatiotemporal Differences in Presentation of CD8 T Cell Epitopes during Hepatitis B Virus Infection

Atefeh Khakpoor, Yi Ni, Antony Chen, Zi Zong Ho, Vincent Oei, Ninghan Yang, Reshmi Giri, Jia Xin Chow, Anthony T. Tan, Patrick T. Kennedy, Mala Maini, Stephan Urban, Antonio Bertoletti

Journal of Virology (American Society for Microbiology) Singapore, Germany, Belgium, UK, 05 February 2019

Virology

Key words:antigen presentation, CD8 T cells, chronic hepatitis B patient, HBV DNA integration, HLA class I, liver, hepatitis B virus

Organism: Human

Tissue: Liver

Pathological State: Virus Infection

26
HIV-1 and SIV Infection Are Associated with Early Loss of Lung Interstitial CD4+ T Cells and Dissemination of Pulmonary Tuberculosis

Björn Corleis, Allison N. Bucsan, Maud Deruaz, Vladimir D. Vrbanac, Antonella C. Lisanti-Park, Samantha J. Gates, Alice H. Linder, Jeffrey M. Paer, Gregory S. Olson, Brittany A. Bowman, Abigail E.S chiff, Benjamin D. Medoff, Andrew M.Tager, Andrew D. Lust

Cell Reports (Cell Press) USA, 05 February 2019

Pulmonology

Key words:HIV-1, CD4+ T cells, cell death, tuberculosis, HIV/TB co-infection, lung, BAL

Organism: Mouse

Tissue: Lung, Spleen

Pathological State: Virus Infection

27
Pathology of spontaneous and immunotherapy‐induced tumor regression in a murine model of melanoma

Kim R M Blenman, Jake Wang, Shawn Cowper, Marcus Bosenberg

Pigment Cell & Melanoma Research (Wiley) USA, 31 January 2019

Oncology

Key words:melanoma, mouse models, B cells, neutrophils, Ly6B.2, histology, tumor regression, NETs

Organism: Mouse

Tissue: Allograft Tumor

Pathological State: Cancer

28
COPD and asthma therapeutics for supportive treatment in organophosphate poisoning

J Herbert, H Thiermann, F Worek, T Wille

Clinical Toxicology (Taylor & Francis) Germany, 30 January 2019

Toxicology

Key words:Organophosphate poisoning, nerve agents, PCLS, COPD, asthma

Organism: Rat

Tissue: Lung

29
Sensory Neuropeptides and their Receptors Participate in Mechano-Regulation of Murine Macrophages

Dominique Muschter , Anna-Sophie Beiderbeck , Tanja Späth, Christian Kirschneck, Agnes Schröder, Susanne Grässel

International journal of Molecular Sciences (MDPI) Germany, 24 January 2019

Immunology

Key words:cyclic stretch; mechan-oregulation; murine macrophages; substance P; alpha-calcitonin gene-related peptide; neurokinin receptor; CGRP receptor; destabilized medial meniscus

Organism: Mouse

Pathological State: Osteoarthritis

Cell Line: Bone Marrow-derived Macrophages

30
Multiple defects sensitize p53-deficient head and neck cancer cells to the WEE1 kinase inhibition

Ahmed Diab, Micheal Kao, Keffy Kehrli, Hee Yeon Kim, Julia Sidorova and Eduardo Méndez

Molecular Cancer Research (AACR) USA, 24 January 2019

Oncology

Key words:Head and neck cancer, WEE1, TP53, cell cycle, mitosis, replication stress, DNA damage

Organism: Human

Cell Line: Primary fibroblast cells (HFF4), Head and neck cancer cell lines UM-SCC-74a

31
Safe Nanocomposite‐Mediated Efficient Delivery of MicroRNA Plasmids for Autosomal Dominant Polycystic Kidney Disease (ADPKD) Therapy

Yen‐Chang Tsai I‐Ling Teng Si‐Tse Jiang Yi‐Che Lee Yuan‐Yow Chiou Fong‐Yu Cheng

Advanced Healthcare Materials (Wiley) Taiwan, 23 January 2019

Nanomedicine

Key words:ADPKD, microRNA, MR,I nanoparticles, plasmid DNA

Organism: Mouse

Tissue: Kidney

Pathological State: Polycystic Kidney Disease

32
Dynamic changes in intramedullary pressure 72 hours after spinal cord injury

Xin Zhang, Chang-Bin Liu, De-Gang Yang, Chuan Qin, Xue-Chao Dong, Da-Peng Li, Chao Zhang, Yun Guo, Liang-Jie Du, Feng Gao, Ming-Liang Yang PhD , Jian-Jun Li

Neural Regeneration research (Publishing House of Neural Regeneration Research) China, 23 January 2019

Neuroscience

Key words:anesthetized; blood-spinal barrier; conscious; edema; hemorrhage; nerve regeneration; neural regeneration; pathological mechanism; pressure measurement; rabbit; secondary spinal cord injury; telemetry

Organism: Rabbit

Tissue: Spinal Cord

Pathological State: Spinal Cord Injury

33
Chronic thromboembolic pulmonary hypertension in Austria and Japan

Stella Chausheva, Akira Naito, Aiko Ogawa, Veronika Seidl, Max-Paul Winter, Smriti Sharma, Roela Sadushi-Kolici, Ioana-Alexandra Campean, Shahroukh Taghavi, Bernhard Moser, Walter Klepetko, Keiichi Ishida, Hiromi Matsubara, Seiichiro Sakao, Irene M.Lang

The Journal of thoracic and cardiovascular surgery (Elsevier) Austria, Japan, 21 January 2019

Cardiology

Key words:Chronic thromboembolic pulmonary hypertension, pulmonary endarterectomy, balloon pulmonary angioplasty,

34
Transplantation of neural precursors generated from spinal progenitor cells reduces inflammation in spinal cord injury via NF-κB pathway inhibition

Kristyna Karova, John V. Wainwright, Lucia Machova-Urdzikova, Rishikaysh V. Pisal, Meic Schmidt, Pavla JendelovaEmail author and Meena Jhanwar-UniyalEmail author

Journal of Neuroinflammation (BMC) Czech Republic, USA, 17 January 2019

Stem Cell Research

Key words:NF-κB, p65, Spinal cord injury, Stem cells transplantation, Inflammation, TNF-α,

Organism: Rat

Tissue: Spinal Cord

Pathological State: Spinal Cord Injury

35
Probiotic Lactobacillus spp. Act Against Helicobacter pylori-induced Inflammation

Yi-Hsing Chen, Wan-Hua Tsai, Hui-Yu Wu, Chun-Ya Chen, Wen-Ling Yeh, Ya-Hui Chen, Hui-Ying Hsu, Wei-Wei Chen, Yu-Wen Chen, Wen-Wei Chang, Tzu-Lung Lin, Hsin-Chih Lai, Yu-Hsin Lin and Chih-Ho Lai

Journal of Clinical Medicine (MDPI) Taiwan, 14 January 2019

Microbiology

Key words:Helicobacter pylori; Lactobacillus; probiotic; inflammation

Organism: Mouse

Tissue: Stomach

Pathological State: Bacterial Infection

36
The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease

Lindsay Kosack, Bettina Wingelhofer, Alexandra Popa, Bojan Vilagos, Anna Orlova, Peter Majek, Katja Parapatics, Alexander Lercher, Benedikt Agerer, Anna Ringler, Johanna Klughammer, Mark Smyth, Kseniya Khamina, Hatoon Baazim, David A. Rosa, Jisung Park, P

Cancer cell (Cell Press) Austria, Canada, UK, Australia, 14 January 2019

Oncology

Key words:ERBB, horizontal transmission, MHC class I, receptor tyrosine kinases, STAT3, Tasmanian devil, transmissible cancer, tumor vulnerability, systems biology xenograft

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

37
Brain-Derived Neurotrophin and TrkB in Head and Neck Squamous Cell Carcinoma

Dudás J, Riml A, Tuertscher R, Pritz C, Steinbichler TB, Schartinger VH, Sprung S, Glueckert R, Schrott-Fischer A, Johnson Chacko L, Riechelmann H

International Journal of Molecular Sciences (MDPI) Austria, 11 January 2019

Oncology

Key words:epithelial–mesenchymal transition; vimentin; cytokeratin; p53 mutation; paraffin embedding; riboprobe

Organism: Human

Tissue: Head, Neck

Pathological State: Cancer

38
An integrated characterization of contractile, electrophysiological, and structural cardiotoxicity of Sophora tonkinensis Gapnep. in human pluripotent stem cell …

Ruiying Wang, Min Wang, Shan Wang, Ke Yang, Ping Zhou, Xueheng Xie, Qi Cheng, Jingxue Ye, Guibo Sun and Xiaobo Sun

Stem Cell Research & Therapy (BMC) China, 11 January 2019

Stem Cell Research

Key words:Cardiotoxicity, Sophora tonkinensis, hiPSC-CMs, Cardio-NLCS

Organism: Human

Cell Line: human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)

39
Clinical significance of c-Met and phospho-c-Met (Tyr1234/1235) in ovarian cancer

L Lim, CC Wu, YT Hsu, FJ Sun, CL Chang

Taiwanese Journal of Obstetrics and Gynecology (Elsevier) Taiwan, 09 January 2019

Oncology

Key words:c-Met, phospho-c-Met, Ovarian cancer

Organism: Human

Tissue: Breast

Pathological State: Cancer

40
High-Throughput Synapse-Resolving Two-Photon Fluorescence Microendoscopy for Deep-Brain Volumetric Imaging In Vivo

Guanghan Meng, Yajie Liang, Sarah Sarsfield, Wan-chen Jiang, Rongwen Lu, Joshua Tate Dudman, Yeka Aponte, Na Ji

eLife (eLife Sciences Publications) USA, 03 January 2019

Neuroscience

Key words:two-photon fluorescence microendoscopy, volumetric imaging, Bessel beam, hippocampus, lateral hypothalamus

Organism: Mouse

Tissue: Brain

41
Genetic labeling reveals temporal and spatial expression pattern of D2 dopamine receptor in rat forebrain

Qing Yu, Ying-Zi Liu, Yan-Bing Zhu, Yao-Yi Wang, Qian Li, Dong-Min Yin

Brain Structure and Function (Springer) China, 02 January 2019

Neuroscience

Key words:Drd2, Knockin rats, Olfactory bulb, Cerebral cortex, Hippocampus 

Organism: Mouse, Rat

Tissue: Brain

43
Loss of the dystonia gene Thap1 leads to transcriptional deficits that converge on common pathogenic pathways in dystonic syndromes

Natalie M Frederick, Parth V Shah, Alessandro Didonna ,Monica R Langley, Anumantha G Kanthasamy, Puneet Opal

Human Molecular Genetics (Oxford Academia) USA, 26 December 2018

Neuroscience

Key words:alleles, phenotype, dopamine, signal transduction, transcription, genetic basal ganglia dystonia homeostasis cytoskeleton embryo genes gliosis mice, knockout movement disorders rna, messenger synaptic transmission up-regulation (physiology) zinc fingers c

Organism: Mouse

Tissue: Brain

44
Effects of cylindrospermopsin on cultured immortalized human airway epithelial cells

Barbara Kubickova, Petra Laboha, Jan-Peter Hildebrandt, Klara Hilscherová, Pavel Babica

Chemosphere (Elsevier) Czech Republic, Germany, 22 December 2018

Toxicology

Key words:Cyanobacteria, Cyanotoxin, HBE, Inhalation toxicity, MAPK

Organism: Human

Cell Line: Human bronchial epithelial cell line (HBE), 16HBE14o- cells

46
Spatial mapping of myeloid cells and macrophages by multiplexed tissue staining

Joshua Saylor, Zhaoxuan Ma, Helen S. Goodridge, Fangjin Huang, Anne E. Cress, Stephen J. Pandol, Stephen L. Shiao, Adriana C. Vidal, Lily Wu, Nicholas G. Nickols, Arkadiusz Gertych and Beatrice S. Knudsen

Frontiers in Immunology (Frontiers Media S.A.) USA, 14 December 2018

Immunology

Key words:FFPE; immunofluorescence; immunohistochemistry; macrophage; multiplex; myeloid; spatial profiling

Organism: Human

Tissue: Colon, Tonsil

Pathological State: Cancer

47
Predominant Striatal Input to the Lateral Habenula in Macaques Comes from Striosomes

Simon Hong, Satoko Amemori, Emily Chung, Daniel J. Gibson, Ken-ich iAmemori , Ann M.Graybiel

Current Biology (Cell Press) USA, Japan, 13 December 2018

Neuroscience

Key words:basal ganglia, dopamine, motivation, non-human primate, mood, learning, microstimulation

Organism: Monkey

Tissue: Brain

48
Melanocyte-specific gene 1 promotes melanoma progression by enhancing the expression of Bcl-2

Hui Zhao, Guosheng Wu, Ji Zhu, Mengyan Sun, Yuchong Wang, Yongjie Fan, Kai Wu, Hongda Bi, Haiying Dai, Chuan Lv, Chunyu Xue

Oncology Letters (Spandidos Publications) China, 12 December 2018

Oncology

Key words:melanocyte-specific gene 1, melanoma, cell viability, apoptosis, Bcl-2

Organism: Human

Tissue: Skin

Pathological State: Cancer

49
The natural polyphenol curcumin induces apoptosis by suppressing STAT3 signaling in esophageal squamous cell carcinoma

Ying Liu, Xinhua Wang, Shuang Zeng, Xiane Zhang, Jimin Zhao, Xiaoyan Zhang, Xinhuan Chen, Wanjing Yang, Yili Yang, Ziming Dong, Jingyu Zhu Xin Xu, Fang Tian

Journal of Experimental & Clinical Cancer Research (Springer) China, 05 December 2018

Oncology

Key words:Curcumin, STAT3, Esophageal squamous cell carcinoma, Apoptosis, PDX model

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

50
Anti-inflammatory compound curcumin and mesenchymal stem cells in the treatment of spinal cord injury in rats.

J Ruzicka, LM Urdzikova, A Kloudova, AG Amin…

Acta Neurobiologiae Experimentalis ( Nencki Institute of Experimental Biology) Czech Republic, USA, 05 December 2018

Regenerative Medicine

Key words:Spinal cord injury, human mesenchymal stem cells, curcumin, combined therapy, inflammatory response

Organism: Rat

Tissue: Spinal Cord

Pathological State: Spinal Cord Injury

Cell Line: Human MSCs

51
Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression

Bing Song, Su-Hong Park, Jonathan C. Zhao, Ka-wing Fong, Shangze Li, Yongik Lee, Yeqing A. Yang, Subhasree Sridhar, Xiaodong Lu, Sarki A. Abdulkadir, Robert L. Vessella, Colm Morrissey, Timothy M. Kuzel, William J. Catalona, Ximing J. Yang, and Jindan Yu

Journal of Clinical Investigation (American Society for Clinical Investigation) USA, China, 04 December 2018

Oncology

Key words:Genetics; Oncology; Prostate cancer

Organism: Human

Tissue: Prostate

Pathological State: Cancer

52
Extracellular vesicles from mature dendritic cells (DC) differentiate monocytes into immature DC

Stefan Schierer, Christian Ostalecki, Elisabeth Zinser, Ricarda Lamprecht, Bianca Plosnita, Lena Stich, Jan Dörrie, ProfileManfred B Lutz, ProfileGerold Schuler, ProfileAndreas S Baur

Life Science Alliance () Germany, Austria, 03 December 2018

Immunology

Key words:Medical Research, Immunology

Organism: Human, Mouse

Cell Line: Monocyte-derived DC

53
Elevated Serum Interleukin-8 Level Correlates with Cancer-Related Cachexia and Sarcopenia: An Indicator for Pancreatic Cancer Outcomes

Ya-Chin Hou , Chih-Jung Wang , Ying-Jui Chao , Hao-Yun Chen , Hao-Chen Wang, Hui-Ling Tung , Jung-Ting Lin and Yan-Shen Shan

Journal of Clinical Medicine (MDPI) Taiwan, 01 December 2018

Oncology

Key words:pancreatic cancer; cancer cachexia; sarcopenia; interleukin (IL)-1β; IL-6; IL-8; tumor necrosis factor (TNF)-α

Organism: Human

Tissue: Pancreas

Pathological State: Cancer

54
Freshwater cyanotoxin cylindrospermopsin has detrimental stage-specific effects on hepatic differentiation from human embryonic stem cells

Tereza Vanova, Jan Raska, Pavel Babica, Iva Sovadinova, Michaela Kunova Bosakova, Petr Dvorak Ludek Blaha, Vladimir Rotrekl

Toxicological Sciences (Oxford University Press) Czech Republic, 30 November 2018

Stem Cell Research

Key words:cylindrospermopsin, hepatic differentiation, human embryonic stem cells, liver, cyanotoxin

Organism: Human

Cell Line: Human embryonic stem cell (hESCs)

55
Pterostilbene Attenuates Hexavalent Chromium-Induced Allergic Contact Dermatitis by Preventing Cell Apoptosis and Inhibiting IL-1β-Related NLRP3 Inflammasome Activation

Bour-Jr Wang , Hui-Wen Chiu, Yong-Lin Lee, Chia-Yi Li, Ying-Jan Wang, and Yu-Hsuan Lee

Journal of Clinical Medicine (MDPI) Taiwan, 27 November 2018

Allergy

Key words:Hexavalent chromium; pterostilbene; endoplasmic reticulum stress; inflammatory cytokines; NLRP3 inflammasome; allergic contact dermatitis

Organism: Mouse

Tissue: Skin

Pathological State: Dermatitis

56
ONECUT2 Is a Targetable Master Regulator of Lethal Prostate Cancer That Suppresses the Androgen Axis

M Rotinen, S You, J Yang, S Coetzee, WC Huang…

Nature Medicine (Nature) USA, Taiwan, 26 November 2018

Oncology

57
Immune Cell and Cell Cluster Phenotyping, Quantitation, and Visualization Using In Silico Multiplexed Images and Tissue Cytometry

Kim R.M. Blenman, Marcus W. Bosenberg

Cytometry Part A (Wiley) USA, 23 November 2018

Cytometry

Key words:immune cells, cell clusters, quantitative imaging, multiplexed histology, tissue cytometry, TissueFAXS in silico analysis, FFPE

Organism: Mouse

Tissue: Spleen

Pathological State: Cancer

58
PD-L1 expression and the prognostic significance in gastric cancer: a retrospective comparison of three PD-L1 antibody clones (SP142, 28–8 and E1L3N)

Jing Ma, Jianhui Li, Meirui Qian, Weili Han, Miaomiao Tian, Zengshan Li, Zhe Wang, Shuixiang He and Kaichun Wu

Diagnostic Pathology (Springer) China, 21 November 2018

Oncology

Key words:Programmed cell death ligand 1, Immunohistochemistry, H-score, Multiplexed immunofluorescence

Organism: Human

Tissue: Stomach

Pathological State: Cancer

59
MicroRNA-451a overexpression induces accelerated neuronal differentiation of Ntera2/D1 cells and ablation affects neurogenesis in microRNA-451a-/- mice

Christa Trattnig , Muammer Üçal , Carmen Tam-Amersdorfer, Angela Bucko, Ulrike Zefferer, Gerda Grünbacher, Markus Absenger-Novak, Kristin Anna Öhlinger, Klaus Kraitsy, Daniel Hamberger, Ute Schaefer , Silke Patz

PLOS ONE (PLOS) Austria, 21 November 2018

Neuroscience

Key words:Neuronal differentiation, Neurites, Cell differentiation, Neurospheres, MicroRNAs , Neural networks, Fluorescence microscopy, Nestin

Organism: Mouse

Tissue: Brain

60
Oxidative muscles have better mitochondrial homeostasis than glycolytic muscles throughout life and maintain mitochondrial function during aging

Annunziata N. Crupi , Jordan S. Nunnelee , David J. Taylor , Amandine Thomas , Jean-Philippe Vit , Celine E. Riera 5 , Roberta A. Gottlieb , Helen S. Goodridge

Aging (Impact Journals) USA, 18 November 2018

Physiology

Key words:Aging; glycolytic; mitochondria; oxidative; sarcopenia; skeletal muscle

Organism: Mouse

Tissue: Muscle

61
Hepatocellular carcinoma-targeted nanoparticles for cancer therapy

Chien-Hsun Wu, Chun-Hsin Lan, Kuan-Lin Wu, Yao‑Ming Wu, Wann-Neng Jane , Michael Hsiao, Han-Chung Wu

International Journal of Oncology (Spandidos Publications) Taiwan, 16 November 2018

Oncology

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

62
Generation of human iPSCs from human prostate cancer-associated fibroblasts IBPi002-A

Zuzana Kahounová, Eva Slabáková, Lucia Binó, Ján Remšík, Radek Fedr, Jan Bouchal, Daniela Kurfűrstová, Radek Vrtěl, Vladimír Študent, Lucie Jurečková, Volodymyr Porokh, Aleš Hampl, Karel Souček

Stem Cell Research (Elsevier) Czech Republic, 16 November 2018

Stem Cell Research

Key words:induced stem cells, iPSCs, prostate fibroblasts, IBPi00-2

Organism: Human

Cell Line: iPSCs (induced pluripotent cells)

63
Effect of dentin matrix components on the mineralization of human mesenchymal stromal cells

Dr. Xenos Petridis, Mr. Bas Pieter Beems, Dr. Phillip Tomson, Dr. Ben Scheven, Dr. Ben Giepmans, Dr. Jeroen Kuipers, Dr. Luc van der Sluis, Dr. Martin C Harmsen

Tissue Engineering - Part A (Mary Ann Liebert Inc.) The Netherlands, UK, 16 November 2018

Tissue Engineering

Key words:dental pulp, dentin matrix, mesenchymal stromal cells, mineralization, tissue engineering, umbilical cord

Organism: Human

Cell Line: DPSCs, ASCs(dental pulp stem cells, Adipose tissue derived stem cells)

64
Semi-Automated and Manual Methods for Counting Cells Expressing P75 Receptor in Endometriotic Lesions

Dewanto Agung, Sun Xiaoyan, Dudas Jozsef, Gluekert Rudolf, Schrott-Fischer Anneliese, W. D. Ludwig, Seeber Beata

() Indonesia, Austria, 12 November 2018

Cytometry

Key words:Observers,Immune system,Software,Lesions,Manuals,Biomedical imaging,Tools

65
Increased frequency of systemic pro-inflammatory Vδ1+ γδ T cells in HIV elite controllers correlates with gut viral load

Gregory S. Olson, Sarah W. Moore, James M. Richter, John J. Garber, Brittany A. Bowman, Crystal A. Rawlings, Meaghan Flagg, Björn Corleis & Douglas S. Kwon

Scientific Reports (Nature) USA, 07 November 2018

Immunology, Virology

Key words:Chronic inflammation, Gammadelta T cells, HIV infections, Infection, Mucosal immunology

Organism: Human

Tissue: Small Intestine

Pathological State: Virus Infection

66
Novel Protective Effects of Cistanche Tubulosa Extract Against Low-Luminance Blue Light-Induced Degenerative Retinopathy

Man-Ru Wua, Cheng-Hui Lina, Jau-Der Hob, George Hsiaoc, Yu-Wen Cheng

Cellular Physiology and Biochemistry (Karger) Taiwan, 07 November 2018

Ophthalmology

Key words:Cistanche tubulosa extract • Blue light • Apoptosis • Retinal pigment epithelial cells

Organism: Human

Cell Line: RPE cells (Retinal pigment epithelium)

67
Loss of BAP1 expression is associated with genetic mutation and can predict outcomes in gallbladder cancer

Takashi Hirosawa, Masaharu Ishida , Kentaro Ishii, Keigo Kanehara, Katsuyoshi Kudo, Shinobu Ohnuma, Takashi Kamei, Fuyuhiko Motoi, Takeshi Naitoh, Florin M. Selaru, Michiaki Unno

PLOS ONE (PLOS) Japan, USA, 05 November 2018

Oncology

Key words:DNA methylation ,Small interfering RNAs ,Polymerase chain reaction ,Methylation ,Mutation detection ,Prognosis ,DNA sequence analysis ,Nonsense mutation

Organism: Human

Tissue: Gallbladder

Pathological State: Cancer

68
Genetic ablation of NFAT5/TonEBP in smooth muscle cells impairs flow- and pressure-induced arterial remodeling in mice

Caroline Arnold, Anja Feldner, Maren Zappe, Dorde Komljenovic, Carolina De La Torre, Philipp Ruzicka, Markus Hecker, Wolfgang Neuhofer, and Thomas Korff

The FASEB Journal (Federation of American Societies for Experimental Biology) Germany, 01 November 2018

Regenerative Medicine

Key words:hypertension, wall stress, transcriptome

Organism: Mouse

Cell Line: Primary aterial SMCs (smooth muscle cells) and VSMCs (vascular smooth muscle cells )

69
Tissue and host species-specific transcriptional changes in models of experimental visceral leishmaniasis

Helen Ashwin , Karin Seifert , Sarah Forrester , Najmeeyah Brown , Sandy MacDonald , Sally James , Dimitris Lagos , Jon Timmis , Jeremy C Mottram , Simon L. Croft , Paul M. Kaye

Wellcome Open Research (Wellcome Open Research) UK, 29 October 2018

Parasitology

Key words:Leishmania, infection, host response, transcriptomics, immunopathology

Organism: Mouse

Tissue: Spleen, Liver

Pathological State: Parasitic Infection

70
Azo-based small molecular hypoxia responsive theranostic for tumor-specific imaging and therapy

Ying Zhoua, Mrinmoy Maitib, Amit Sharmac, Miae Won, Le Yu, Lan Xi, Miao, Jinwoo Shin, Arup Podder, Kondapa Naidu Bobba, Jiyou Han, Sankarprasad Bhuniya, Jong Seung Kim

Journal of Controlled Release (Elsevier) China, India, South Korea, 28 October 2018

Oncology

Key words:molecular hypoxia, theranostic, tumor-specific imaging,

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

71
PI3K: A master regulator of brain metastasis‐promoting macrophages/microglia

Raquel Blazquez Darius Wlochowitz Alexander Wolff Stefanie Seitz Astrid Wachter Julia Perera‐Bel Annalen Bleckmann Tim Beißbarth Gabriela Salinas Markus J. Riemenschneider Martin Proescholdt Matthias Evert Kirsten Utpatel Laila Siam Bawarjan Sc

Glia (Wiley) Germany, 25 October 2018

Oncology

Key words:Astrocytes; BKM120; brain metastasis; macrophages; microglia; PI3K; RPPA

Organism: Mouse

Pathological State: Cancer

Cell Line: MDMs (Monocyte‐derived macrophages)

72
Alteration of mesenchymal stem cells polarity by laminar shear stimulation promoting β-catenin nuclear localization

Wei-TaChen, Wei-Tse Hsu, Meng-Hua Yen, Chun A. Changou, Chia-Li Han, Yu-Ju Chen, Ji-Yen Cheng, Tzu-Hao Chang, Oscar Kuang-Sheng Lee, Jennifer Hui-Chun Ho

Biomaterials (Elsevier) Taiwan, 23 October 2018

Stem Cell Research

Key words:β-catenin, Cardiovascular, Laminar shear, Mesenchymal stem cells, Wnt

Organism: Human

Cell Line: MSCs (mesenchymal stem cells)

73
Gene expression profiling in a mouse model of Dravet syndrom

Nicole A.Hawkins, Jeffrey D.Calhoun, Alexandra M.Huffman, Jennifer A.Kearney

Experimental Neurology (Elsevier) USA, 19 October 2018

Neuroscience

Key words:Epilepsy; Epileptic encephalopathy; Gene expression; RNA-seq; Seizure; Voltage-gated sodium channel

Organism: Mouse

Tissue: Brain

Pathological State: Dravet Syndrome

74
Kinin-B2 Receptor Activity in Skeletal Muscle Regeneration and Myoblast Differentiation

Janaina M. Alves, Antonio H. Martins, Claudiana Lameu, Talita Glaser, Nawal M. Boukli, Vinicius Bassaneze, Rafael Dariolli, Isis C. Nascimento, Poliana C. M. Martins, Héllio D. N. de Souza, José Eduardo Krieger, Dulce E. Casarini, Vicencia M. Sales, João

Stem cell reviews and reports (Springer) USA, Brazil, 18 October 2018

Stem Cell Research

Key words:Mouse myoblast differentiation, Muscle repair, Kinin-B2 receptor, HOE-140

Organism: Mouse

Cell Line: C2C12 Cells (myoblast cell line)

75
Early Immunologic Response of Irreversible Electroporation versus Cryoablation in a Rodent Model of Pancreatic Cancer

Sarah B. White, MD, MS, FSIR, Zhouli Zhang, MD, PhD, Jeane Chen, PhD, Venkateswara R. Gogineni, PhD, and Andrew C. Larson, PhD

Journal of Vascular and Interventional Radiology (Elsevier) USA, 11 October 2018

Immunology

Key words:irreversible electroporation, Cryoablation, Pancreatic Cancer

Organism: Mouse

Pathological State: Cancer

Cell Line: PANC-2 (Pancreatic cancer cell line)

76
Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting

Mera vCohen, Amir Giladi, Anna-Dorothea Gorki, Dikla Gelbard Solodkin, Mor Zada, Anastasiya Hladik, Andras Miklosi, Tomer-Meir Salame, Keren Bahar Halpern, Eyal David, Shalev Itzkovitz, Tibor Harkany, Sylvia Knapp, Ido Amit

Cell (Cell Press) Israel, Austria, Sweden, 11 October 2018

Cell Biology

Key words:immune systemsingle-cell RNA sequencinglungbasophilsalveolar macrophagescellular interactiondevelopmentsignaling

Organism: Mouse

Tissue: Lung

77
Transforming growth factor beta 1 mediates the low-frequency vertical vibration enhanced production of tenomodulin and type I collagen in rat Achilles tendon

Chia-Hsin Chen, Yi-Hsiung Lin, Chung-Hwan Chen, Yan-Hsiung Wang, Ming-Long Yeh, Tsung-Lin Cheng, Chau-Zen Wang

PLOS ONE (PLOS) Taiwan, 11 October 2018

Cell Biology

Key words:Tendons ,Collagens ,Gene expression ,Stiffness ,Vibration ,Mechanical properties ,Enzyme-linked immunoassays ,Polymerase chain reaction

Organism: Rat

Tissue: Tendon

78
Inhibition of AKT suppresses the initiation and progression of BRCA1-associated mammary tumors

Hye Jung Baek, Sun Eui Kim, Jong Kwang Kim, Dong Hoon Shin, Tae Hyun Kim, Kwang Gi Kim, Chu-Xia Deng, Sang Soo Kim

International Journal of Biological Sciences (Ivyspring International Publisher) South Korea, China, 10 October 2018

Oncology

Key words:BRCA1, AKT, MK-2206, precision medicine

Organism: Mouse

Tissue: Breast

Pathological State: Cancer

79
Accelerated Aging and Clearance of Host Anti-inflammatory Enzymes by Discrete Pathogens Fuels Sepsis

Yang WH, Heithoff DM, Aziz PV, Haslund-Gourley B, Westman JS, Narisawa S, Pinkerton AB, Millán JL, Nizet V, Mahan MJ, Marth JD

Cell Host and Microbe (Cell Press) USA, 10 October 2018

Immunology, Microbiology

Key words:glycosylation, sepsis, neuraminidase, Toll-like receptor 4, alkaline phosphatase, Ashwell-Morell receptor, lipopolysaccharide, inflammation

Organism: Mouse

Tissue: Liver

Pathological State: Sepsis

80
Extracellular domain of EpCAM enhances tumor progression through EGFR signaling in colon cancer cells

Kang-Hao Liang, Hsien-Cheng Tso, Shao-Hsi Hung, I.-I. Kuan, Jun-Kai Lai, Feng-Yi Ke, Yi-Ting Chuang, I-Ju Liu, Yi-Ping Wang, Ruey-Hwa Chen, Han-Chung Wu

Cancer Letters (Elsevier) Taiwan, 01 October 2018

Oncology

Key words:Epithelial cell adhesion molecule, Regulated intramembrane proteolysis, β-catenin, HIF1α

Organism: Human

Tissue: Colon

Pathological State: Cancer

81
Age, but not short-term intensive swimming, affects chondrocyte turnover in zebrafish vertebral cartilage

Quan-Liang Jian​, Wei-Chun HuangFu​, Yen-Hua Lee, I-Hsuan Liu​

PeerJ - The Journal of Life and Environmental Sciences (PeerJ) Taiwan, 01 October 2018

Osteology

Key words:Aging, Cartilage, Osteoarthritis, Tissue homeostasis, Chondrocyte

Organism: Fish

Tissue: Spinal Cord

82
Gd-EOB-DTPA DCE-MRI biomarkers in a rabbit model of liver fibrosis

Yang Ji, Chuanshan Zhang, Zhe Huang, Xia Wang, Lina Yue, Meimei Gao, Huiling Hu, Qinjun Su, Yuedong Han, Bin Liu, Ding Yang, Zhanliang Su, Zhuoli Zhang

American Journal of Translational Research (e-Century Publishing Corporation) China, USA, 30 September 2018

Hepathology

Key words:Liver fibrosis, animal, magnetic resonance imaging, pathology

Organism: Rabbit

Tissue: Liver

Pathological State: Fibrosis, Liver Cirrhosis

83
Modified Ginseng Extract Induces Apoptosis in HepG2 Cancer Cells by Blocking the CXCL8-Mediated Akt/Nuclear Factor-κB Signaling Pathway

Zhen Yang Cui, Eunbi Jo, Hyun Jin Jang, In-Hu Hwang, Kyung-Bok Lee, Hwa-Seung Yoo, Soo Jung Park, Mi-Kyung Jung, Yeon Wol Lee and Ik-Soon Jang

The American Journal of Chinese Medicine (World Scientific) South Korea, 27 September 2018

Oncology

Key words:Modified Regular Ginseng Extract; MRGX; C-X-C Motif Chemokine Ligand 8; Liver Cancer; Akt; Nuclear Factor-κB; Apoptosis

Organism: Human

Pathological State: Cancer

Cell Line: HepG2 (Liver carcinoma cell line)

84
Development of Decellularized Cornea by Organic acid Treatment for Corneal Regeneration

Mr. HungJun Lin, Dr. TsungJen Wang, Miss TingWei Li, Dr. YaoYuan Chang, Prof. Ming Thau Sheu, Prof. Yi-You Huang, Dr. Der-Zen Liu

Tissue Engineering - Part A (Mary Ann Liebert Inc.) Taiwan, 22 September 2018

Tissue Engineering

Key words:cornea; decellularized scaffold; extracellular matrix; xenograft; corneal transplantation.

Organism: Rabbit

Tissue: Eye

85
The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases

Bohumil Fafilek, Lukas Balek, Michaela Kunova Bosakova, Miroslav Varecha, Alexandru Nita, Tomas Gregor, Iva Gudernova, Jitka Krenova, Somadri Ghosh, Martin Piskacek, Lucie Jonatova, Nicole H. Cernohorsky, Jennifer T. Zieba, Michal Kostas, Ellen Margrethe

Science Signaling (American Association for the Advancement of Science) Czech Republic, Belgium, USA, Norway, 18 September 2018

Cell Biology

Key words:SHIP2, ERK activation, FGF receptors, Src kinases

Organism: Rat, Human

Pathological State: Cancer

Cell Line: U2OS (Osteosarcoma cell line), RCS cells (Cultured rat chondrosarcoma cell line)

86
ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific manner

Jacqueline A. Brosnan-Cashman, Ming Yuan, Mindy K. Graham, Anthony J. Rizzo, Kaylar M. Myers, Christine Davis, Rebecca Zhang, David M. Esopi, Eric H. Raabe, Charles G. Eberhart, Christopher M. Heaphy, Alan K. Meeker

PLOS ONE (PLOS) USA, 18 September 2018

Oncology

Key words:Telomeres, Cloning, Glioma cells ,Glioma ,DNA cloning ,Immunoblotting ,Vector cloning ,Polymerase chain reaction

Organism: Human

Pathological State: Cancer

Cell Line: Glioma cell lines (MOG-G-UVW, SF188, U-251 and UW479)

87
Activation of estrogen receptor alpha induces beiging of adipocytes

Roberta S.Santos, Aaron P.Frank, Luciana A.Fátima, Biff F.Palmer, Deborah J.Clegg

Molecular Metabolism (Elsevier) USA, 15 September 2018

Cell Biology

Key words:Beige adipocytes, Lipolysis, Estrogen receptor alpha (ERα), Obesity, Type II diabetes mellitus (T2DM)

Organism: Mouse

Tissue: Adipose Tissue

88
Cellular-scale probes enable stable chronic subsecond monitoring of dopamine neurochemicals in a rodent model

Helen N. Schwerdt, Elizabeth Zhang, Min Jung Kim, Tomoko Yoshida, Lauren Stanwicks, Satoko Amemori, Huseyin E. Dagdeviren, Robert Langer, Michael J. Cima & Ann M. Graybiel

Communications Biology (Nature) USA,, 12 September 2018

Neuroscience

Key words:Diagnostic markers, Neurochemistry, Parkinson's disease, Sensors and probes

Organism: Rat

Tissue: Brain

89
Synthetic α5β1 integrin ligand PHSRN is proangiogenic and neuroprotective in cerebral ischemic stroke

Cheng-Chun Wu, Liang-Chao Wang, Yu-Tin Su, Wei-Yen Wie, Kuen-Jer Tsai

Biomaterials (Elsevier) Taiwan, 11 September 2018

Biological Materials

Key words:Stroke, Fibronectin, PHSRN, α5β1, Angiogensis, Neurogenesis, VEGF

Organism: Rat

Tissue: Brain

90
Phenethyl Isothiocyanate Inhibits In Vivo Growth of Xenograft Tumors of Human Glioblastoma Cells

Yu-Cheng Chou, Meng-Ya Chang, Hsu-Tung Lee, Chiung-Chyi Shen, Tomor Harnod, Yea-Jiuan Liang, Rick Sai-Chuen Wu, Kuang-Chi Lai, Fei-Ting Hsu, Jing-Gung Chung

Molecules (MDPI) Taiwan, 10 September 2018

Oncology

Key words:phenethyl isothiocyanate; apoptosis; xenograft; caspase; glioblastoma

Organism: Mouse

Tissue: Liver, Xenograft Tumor

Pathological State: Cancer

91
Factor Xa inhibition by rivaroxaban regulates fibrogenesis in human atrialfibroblasts with modulation of nitric oxide synthesis and calciumhomeostasis

Cheng-Chih Chung, Yung-Kuo Lin, Yao-Chang Chen, Yu-Hsun Kao, Yung-Hsin Yeh, Yi-Jen Chen

Journal of Molecular and Cellular Cardiology (Elsevier) Taiwan, 10 September 2018

Physiology

Key words:Fibroblasts, Fibrosis, Rivaroxaban, Protease-activated receptor, Atrial fibrillation, Stroke

Organism: Rat

Tissue: Heart

Pathological State: Fibrosis

92
Androgen receptor expression inversely correlates with immune cell infiltration in human epidermal growth factor receptor 2–positive breast cancer

Johan M. van Rooijen, Si-Qi Qiu, Hetty Timmer-Bosscha, Bert van der Vegt, James E. Boers, Carolien P. Schröder, Elisabeth G.E. de Vries

European Journal of Cancer (Elsevier) The Netherlands, China, 09 September 2018

Oncology

Key words:Androgen receptor expression, HER2-positive metastatic breast cancer, Immune cell infiltration, Trastuzumab resistance

Organism: Human

Tissue: Breast

Pathological State: Cancer

93
TLR7 agonist attenuates acetylcholine‐induced, Ca2+‐dependent ionic currents in swine tracheal submucosal gland cells

Shunichi Gamo, Tsutomu Tamada, Koji Murakami, Soshi Muramatsu, Hidemi Aritake, Masayuki Nara, Itsuro Kazama, Tatsuma Okazaki, Hisatoshi Sugiura, Masakazu Ichinose

Experimental Physiology (Wiley) Japan, 08 September 2018

Physiology

Key words:CaCC, COPD, hypersecretion, R837, submucosal glands

Organism: Pig, Human

Tissue: Lung, Spleen

94
Inhibitory control of prefrontal cortex by the claustrum

Jesse Jackson, Mahesh M. Karnani, Boris V. Zemelman, Denis Burdakov, Albert K. Lee

Neuron (Cell Press) USA, UK, Canada, 05 September 2018

Neuroscience

Key words:claustrum prefrontal NPY PV neocortex feed-forward inhibition microcircuit neurogliaform cell somatostatin interneuron VIP

Organism: Mouse

Tissue: Brain

95
Oxidized Low-Density Lipoprotein-Deteriorated Psoriasis Is Associated with the Upregulation of Lox-1 Receptor and Il-23 Expression In Vivo and In Vitro

Chun-Ming Shih, Chien-Yu Huang, Kuo-Hsien Wang, Chun-Yao Huang, Po-Li Wei, Yu-Jia Chang, Chi-Kun Hsieh, Kuan-Ting Liu, Ai-Wei Lee

International Journal of Molecular Sciences (MDPI) Taiwan, 03 September 2018

Dermatology

Key words:oxLDL; LOX-1; psoriasis

Organism: Mouse

Tissue: Skin

Pathological State: Psoriasis

96
Amentoflavone Inhibits Hepatocellular Carcinoma Progression Through Blockage of ERK/NF-ĸB Activation

Kun-Ching Lee, Wei-Ting Chen, Yu-Chang Liu, Song-Shei Lin, Fei-Ting Hsu

in vivo: international journal of experimental and clinical pathophysiology and drug research (International Institute of Anticancer Research) Taiwan, 01 September 2018

Oncology

Key words:Amentoflavone, hepatocellular carcinoma, extracellular signal-regulated kinase, nuclear factor-kappaB, bioluminescence imaging.

Organism: Mouse

Tissue: Xenograft Tumor

Pathological State: Cancer

97
Enhanced Sternal Healing via Platelet-Rich Plasma and Biodegradable Gelatin Hydrogel

Masafumi Shibata, Gen Takagi, Mitsuhiro Kudo, Jiro Kurita, Yoko Kawamoto, Yasuo Miyagi, Mikimoto Kanazashi, Takashi Sakatani, Zenya Naito, Yasuhiko Tabata, Masaaki Miyamoto, and Takashi Nitta

Tissue Engineering Part A (Mary Ann Liebert) Japan, 01 September 2018

Tissue Engineering

Organism: Rabbit

Tissue: Bone

98
The tree shrew cerebellum atlas: Systematic nomenclature, neurochemical characterization and afferent projections

Rong‐Jun Ni Zhao‐Huan Huang Peng‐Hao Luo Xiao‐Hong Ma Tao Li Jiang‐Ning Zhou

Journal of Comparative Neurology (Wiley) China, 29 August 2018

Neuroscience

Key words:cerebellar nuclei, lobule fissure, inferior olive, Purkinje cell, calbindin, RRID: AB_476894

Organism: Treeshrew

Tissue: Brain

99
Focused Ultrasound-Induced Blood-Brain Barrier Opening Enhances GSK-3 Inhibitor Delivery for Amyloid-Beta Plaque Reduction

Po-Hung Hsu, Ya-Tin Lin, Yi-Hsiu Chung, Kun-Ju Lin, Liang-Yo Yang, Tzu-Chen Yen & Hao-Li Liu

Scientific Reports (Nature) Taiwan, 27 August 2018

Neuroscience

Key words:Alzheimer's diseas, eBiomedical engineering ,Blood–brain barrier, Drug delivery, Translational research, GSK-3, Amyloid-Beta Plaque

Organism: Mouse

Tissue: Brain

Pathological State: Alzheimer’s Disease

100
Role of the orexin 2 receptor in palatable-food consumption-associated cardiovascular reactivity in spontaneously hypertensive rats

Shang-Cheng Huang, Tzu-Ling Li, Yen-Hsien Lee, Yu-Wen E. Dai, Yu-Chun Chen Ling-Ling Hwang

Scientific Reports (Nature) Taiwan, 23 August 2018

Cardiology

Key words:Hypertension, Hypothalamus

Organism: Rat

Tissue: Brain

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