The IF Pyknotic Nuclei APP provides tissue detection and cell segmentation in combination with the detection of pyknotic nuclei (defined as completely condensed, round, high intensity nuclei) based on nuclei staining. Additionally, the APP allows to determine the cellular phenotype of specific IF stained cell populations as well as dot detection. It segments the detected cells into nucleus, and/or perinuclear area and/or cytoplasm. As outcome the APP provides parameters such as number, mean intensity and percentage of specific cell populations (including cells containing pyknotic nuclei), as well as dot parameters per segmented cell including count, mean intensity, total dot area, and sum of intensity as well as area and intensity list for all single dots.
App Category 3