StrataQuest APP analysis examples

In the following some examples for analyses done with StrataQuest APPs are shown.

 

IF Immune Status in situ APP: Distance of tumor cells from blood vessels

IF Immune Status in situ APP: Distance of tumor cells from blood vessels

The following example was analysed using a combination of the IF Immune Status in siu APP and the FL version of the Angio APP. It was done for the Johns Hopkins Hospital in New York.

The aim was to evaluate the distance of tumor cells from blood vessels within the tumor cell clusters.

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Adipocyte APP: Measurement of cell size

IHC Adipocyte APP: Measurement of cell size

The Adipocyte APP was designed from the ground up to be run in routine by staff untrained in image analysis and image processing.

The picture set is loaded into StrataQuest and the results are calculated.

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Analysis of cyclic stain and bleach samples

Analysis of cyclic stain and bleach samples

Multi-epitope ligand cartography (MELC) is a technology using samples subjected to cycles of fluorescent staining, imaging and photobleaching. Each cycle can use an antibody for a different protein. The result is a set of images of the distributions of many proteins for the same samples.

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IHC Meta.Cells APP: Stroma and tumor detection on morphological stains

IHC Meta.Cells APP: Stroma and tumor detection on morphological stains

One of the main strenghts of StrataQuest is the capability to segment morphological structures based on a morphological stain alone (i.e. without a specific staining of the structure to be detected).

In this case, the task was made more difficult due to many very thin areas of stroma.

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